Gene Symbol | csr-1 |
Entrez Gene ID | 177591 |
Full Name | Chromosome-Segregation and RNAi deficient |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » csr-1 cDNA ORF clone
Gene Symbol | csr-1 |
Entrez Gene ID | 177591 |
Full Name | Chromosome-Segregation and RNAi deficient |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
mRNA | Protein | Name |
---|---|---|
NM_001047473.4 | NP_001040938.1 | Piwi domain-containing protein |
NM_001047473.3 | NP_001040938.1 | Chromosome-Segregation and RNAi deficient |
NM_001047474.1 | NP_001040939.1 | Chromosome-Segregation and RNAi deficient |
NM_001047474.2 | NP_001040939.1 | Piwi domain-containing protein |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Disruption of CSR-1 results in differential dauer-deficient phenotypes that are dependent upon the experienced environmental stress. CSR-1 is required for expression of a subset of G proteins with functions in the detection of pheromone components.
Title: Endogenous RNAi Pathways Are Required in Neurons for Dauer Formation in
The CSR-1 pathway helps maintain the directionality of active transcription, thereby propagating the distinction between transcriptionally active and silent genomic regions.
Title: Global effects of the CSR-1 RNA interference pathway on the transcriptional landscape.
Study shows that the CSR-1 Argonaute functions with ALG-3/4 to positively regulate target genes required for spermiogenesis; these findings are consistent with a model in which ALG-3/4 and CSR-1 and their associated small RNAs provide an epigenetic memory of paternal gene expression, thereby ensuring the transgenerational continuity of a robust spermiogenic program.
Title: Argonautes promote male fertility and provide a paternal memory of germline gene expression in C. elegans.
It was shown that CSR-1 directly binds to histone mRNA in an ego-1-dependent manner. Increasing the dosage of histone genes rescued the lethality associated with depletion of CSR-1 and EGO-1.
Title: CSR-1 RNAi pathway positively regulates histone expression in C. elegans.
The cde-1 gene, K10D2.3, encodes the TRF-like nucleotidyltransferases CDE-1, study found that CDE-1 is required for the uridylation of CSR-1 bound siRNAs and chromosome segregation.
Title: CDE-1 affects chromosome segregation through uridylation of CSR-1-bound siRNAs.
The following csr-1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the csr-1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCa343754 | |
Clone ID Related Accession (Same CDS sequence) | NM_001047474.1 , NM_001047474.2 | |
Accession Version | NM_001047474.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2604bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Chromosome-Segregation and RNAi deficient | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003282). COMPLETENESS: incomplete on both ends. |
1 | ATGAATCAGA AGCAAAATCC AAGACTTGCC CTGAACATCT TCGGGCTTGA GCTCTCTGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001040939.1 |
CDS | 1..2604 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001047474.1 |
1 | ATGAATCAGA AGCAAAATCC AAGACTTGCC CTGAACATCT TCGGGCTTGA GCTCTCTGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa343754 | |
Clone ID Related Accession (Same CDS sequence) | NM_001047474.1 , NM_001047474.2 | |
Accession Version | NM_001047474.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2604bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Piwi domain-containing protein | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003282). On Sep 4, 2019 this sequence version replaced NM_001047474.1. |
1 | ATGAATCAGA AGCAAAATCC AAGACTTGCC CTGAACATCT TCGGGCTTGA GCTCTCTGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001040939.1 |
CDS | 5..2608 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001047474.2 |
1 | ATGAATCAGA AGCAAAATCC AAGACTTGCC CTGAACATCT TCGGGCTTGA GCTCTCTGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa343753 | |
Clone ID Related Accession (Same CDS sequence) | NM_001047473.4 , NM_001047473.3 | |
Accession Version | NM_001047473.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3093bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Piwi domain-containing protein | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003282). On Sep 4, 2019 this sequence version replaced NM_001047473.3. |
1 | ATGCAGTCGG ATAATGTCGG TCGTGGCCGT GGAAGCCGTG GTGGTTCTCG TGGAGGTAGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001040938.1 |
CDS | 76..3168 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001047473.4 |
1 | ATGCAGTCGG ATAATGTCGG TCGTGGCCGT GGAAGCCGTG GTGGTTCTCG TGGAGGTAGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa343753 | |
Clone ID Related Accession (Same CDS sequence) | NM_001047473.4 , NM_001047473.3 | |
Accession Version | NM_001047473.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3093bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Chromosome-Segregation and RNAi deficient | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003282). On Jun 26, 2012 this sequence version replaced NM_001047473.2. COMPLETENESS: incomplete on both ends. |
1 | ATGCAGTCGG ATAATGTCGG TCGTGGCCGT GGAAGCCGTG GTGGTTCTCG TGGAGGTAGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001040938.1 |
CDS | 1..3093 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001047473.3 |
1 | ATGCAGTCGG ATAATGTCGG TCGTGGCCGT GGAAGCCGTG GTGGTTCTCG TGGAGGTAGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |