Gene Symbol | zyg-1 |
Entrez Gene ID | 173956 |
Full Name | Probable serine/threonine-protein kinase zyg-1 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » zyg-1 cDNA ORF clone
Gene Symbol | zyg-1 |
Entrez Gene ID | 173956 |
Full Name | Probable serine/threonine-protein kinase zyg-1 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
mRNA | Protein | Name |
---|---|---|
NM_062702.5 | NP_495103.1 | Probable serine/threonine-protein kinase zyg-1 |
NM_062702.6 | NP_495103.1 | Probable serine/threonine-protein kinase zyg-1 |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Structure of the C. elegans ZYG-1 cryptic polo box suggests a conserved mechanism for centriolar docking of Plk4 kinases.
Title: Structure of the C. elegans ZYG-1 cryptic polo box suggests a conserved mechanism for centriolar docking of Plk4 kinases.
Direct interactions of the SAS-6 coiled coil with ZYG-1 and SAS-5 are required to recruit SAS-6 to the mother centriole.
Title: Direct binding of SAS-6 to ZYG-1 recruits SAS-6 to the mother centriole for cartwheel assembly.
Data show that levels of the C. elegans Plk4 homolog ZYG-1 are elevated by impairing proteasome or SCF function, indicating that ZYG-1 is regulated by a conserved mechanism.
Title: The C. elegans F-box proteins LIN-23 and SEL-10 antagonize centrosome duplication by regulating ZYG-1 levels.
Data reveal differences in the regulation of mitotic and meiotic centrosome duplication, particularly with regard to ZYG-1 activity, and reveal an important role for centrosomes in spermatid formation.
Title: Control of mitotic and meiotic centriole duplication by the Plk4-related kinase ZYG-1.
Study demonstrates that the kinase ZYG-1 phosphorylates the coiled-coil protein SAS-6 at serine 123 in vitro; this phosphorylation event is crucial for centriole formation in vivo.
Title: Phosphorylation of SAS-6 by ZYG-1 is critical for centriole formation in C. elegans embryos.
The following zyg-1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the zyg-1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCa338699 | |
Clone ID Related Accession (Same CDS sequence) | NM_062702.5 , NM_062702.6 | |
Accession Version | NM_062702.5 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2121bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Probable serine/threonine-protein kinase zyg-1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003280). On Jun 26, 2012 this sequence version replaced NM_062702.4. COMPLETENESS: incomplete on both ends. |
1 | ATGAGCGGTG GGAAGAGTGG TTCAAGATTG AGTGCCTATT CACATTTAAA AGAAATCGGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_495103.1 |
CDS | 1..2121 |
Translation |
Target ORF information:
Target ORF information:
|
NM_062702.5 |
1 | ATGAGCGGTG GGAAGAGTGG TTCAAGATTG AGTGCCTATT CACATTTAAA AGAAATCGGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa338699 | |
Clone ID Related Accession (Same CDS sequence) | NM_062702.5 , NM_062702.6 | |
Accession Version | NM_062702.6 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2121bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Probable serine/threonine-protein kinase zyg-1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003280). On Sep 4, 2019 this sequence version replaced NM_062702.5. |
1 | ATGAGCGGTG GGAAGAGTGG TTCAAGATTG AGTGCCTATT CACATTTAAA AGAAATCGGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_495103.1 |
CDS | 27..2147 |
Translation |
Target ORF information:
Target ORF information:
|
NM_062702.6 |
1 | ATGAGCGGTG GGAAGAGTGG TTCAAGATTG AGTGCCTATT CACATTTAAA AGAAATCGGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |