Gene Symbol | CLP1 |
Entrez Gene ID | 854424 |
Full Name | cleavage polyadenylation factor subunit CLP1 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » CLP1 cDNA ORF clone
Gene Symbol | CLP1 |
Entrez Gene ID | 854424 |
Full Name | cleavage polyadenylation factor subunit CLP1 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001183669.1 | NP_014893.1 | cleavage polyadenylation factor subunit CLP1 |
Saccharomyces cerevisiae (baker's yeast) | CLP1 | NP_014893.1 |
Neurospora crassa | NCU06314 | XP_962576.1 |
Eremothecium gossypii | AGOS_AAL095W | NP_982447.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_08804 | XP_003719167.1 |
Kluyveromyces lactis | KLLA0C09988g | XP_452644.1 |
Schizosaccharomyces pombe (fission yeast) | SPAC22H10.05c | NP_593741.1 |
The nucleotide sequence of Saccharomyces cerevisiae chromosome XV.
Dujon B, Albermann K, Aldea M, Alexandraki D, Ansorge W, Arino J, Benes V, Bohn C, Bolotin-Fukuhara M, Bordonn? R, Boyer J, Camasses A, Casamayor A, Casas C, Ch?ret G, Cziepluch C, Daignan-Fornier B, Dang DV, de Haan M, Delius H, Durand P, Fairhead C, Feldmann H, Gaillon L, Kleine K
Nature387(6632 Suppl)98-102(1997 May)
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
X-ray crystallographic evidence of an extended binding interface of Pcf11p with Clp1p which is likely to be S. cerevisiae specific.
Title: Structural basis for ATP loss by Clp1p in a G135R mutant protein.
The results define Clp1 as a bridge between CF IA and Cleavage-Polyadenylation Factor and indicate that the Clp1-Pcf11 interaction is modulated by amino acids in the conserved ATP-binding site of Clp1.
Title: The interaction of Pcf11 and Clp1 is needed for mRNA 3'-end formation and is modulated by amino acids in the ATP-binding site.
CF IA is reconstituted from Rna14, Rna15, Pcf11, and Clp1 proteins in 2:2:1:1 stoichiometry.
Title: Reconstitution of CF IA from overexpressed subunits reveals stoichiometry and provides insights into molecular topology.
results support a structural role for the Clp1 P-loop motif. ATP binding by Clp1 likely contributes to CF IA formation and cross-factor interactions during the dynamic process of 3' end formation
Title: The P-loop domain of yeast Clp1 mediates interactions between CF IA and CPF factors in pre-mRNA 3' end formation.
Molecular model of a ternary complex of Clp1-ATP and the Clp1-binding region of Pcf11.
Title: Structure of a nucleotide-bound Clp1-Pcf11 polyadenylation factor.
The following CLP1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CLP1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi03542 | |
Clone ID Related Accession (Same CDS sequence) | NM_001183669.1 | |
Accession Version | NM_001183669.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1338bp) Protein sequence SNP |
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Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | cleavage polyadenylation factor subunit CLP1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001147). ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGGCAAGTC TACCTGGTAT TGATGAGCAT ACTACCTCTG AAGAATTGAT AACTGGTGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_014893.1 |
CDS | 1..1338 |
Translation |
Target ORF information:
Target ORF information:
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1 | ATGGCAAGTC TACCTGGTAT TGATGAGCAT ACTACCTCTG AAGAATTGAT AACTGGTGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The nucleotide sequence of Saccharomyces cerevisiae chromosome XV. |
Life with 6000 genes. |