Gene Symbol | MRS4 |
Entrez Gene ID | 853926 |
Full Name | Fe(2+) transporter |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » MRS4 cDNA ORF clone
Gene Symbol | MRS4 |
Entrez Gene ID | 853926 |
Full Name | Fe(2+) transporter |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001179842.1 | NP_012978.1 | Fe(2+) transporter |
Pan troglodytes (chimpanzee) | SLC25A37 | XP_001159098.1 |
Eremothecium gossypii | AGOS_ACR260W | NP_983662.1 |
Homo sapiens (human) | SLC25A37 | NP_057696.2 |
Gallus gallus (chicken) | SLC25A37 | XP_417682.2 |
Caenorhabditis elegans (roundworm) | mfn-1 | NP_496447.1 |
Kluyveromyces lactis | KLLA0E15445g | XP_454647.1 |
Arabidopsis thaliana (thale cress) | AT2G30160 | NP_180577.1 |
Oryza sativa (rice) | Os03g0296800 | NP_001049833.1 |
SLC25A37 | XP_001106001.1 | |
Drosophila melanogaster (fruit fly) | mfrn | NP_651600.1 |
Schizosaccharomyces pombe (fission yeast) | SPAC8C9.12c | NP_594283.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_03564 | XP_003716352.1 |
Xenopus tropicalis (tropical clawed frog) | slc25a37 | XP_002932597.1 |
Canis lupus familiaris (dog) | SLC25A37 | XP_849447.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP006030 | XP_001237747.2 |
Saccharomyces cerevisiae (baker's yeast) | MRS3 | NP_012402.1 |
Saccharomyces cerevisiae (baker's yeast) | MRS4 | NP_012978.1 |
Neurospora crassa | NCU02423 | XP_959605.1 |
Mus musculus (house mouse) | Slc25a37 | NP_080607.2 |
Rattus norvegicus (Norway rat) | Slc25a37 | NP_001014018.1 |
Danio rerio (zebrafish) | slc25a37 | NP_001035060.1 |
Arabidopsis thaliana (thale cress) | AT1G07030 | NP_172184.1 |
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
Complete DNA sequence of yeast chromosome XI.
Dujon B, Alexandraki D, Andr? B, Ansorge W, Baladron V, Ballesta JP, Banrevi A, Bolle PA, Bolotin-Fukuhara M, Bossier P, Bou G, Boyer J, Bultrago MJ, Cheret G, Colleaux L, Dalgnan-Fornler B, del Rey F, Dlon C, Domdey H, D?sterhoft A, D?sterhus S, Entlan KD, Erfle H, Esteban PF, Feldmann H, Fernandes L, Robo GM, Fritz C, Fukuhara H, Gabel C, Gaillon L, Carcia-Cantalejo JM, Garcia-Ramirez JJ, Gent NE, Ghazvini M, Goffeau A, Gonzal?z A, Grothues D, Guerreiro P, Hegemann J, Hewitt N, Hilger F, Hollenberg CP, Horaitis O, Indge KJ, Jacquier A, James CM, Jauniaux C, Jimenez A, Keuchel H, Kirchrath L, Kleine K, K?tter P, Legrain P, Liebl S, Louis EJ, Maia e Silva A, Marck C, Monnier AL, M?stl D, M?ller S, Obermaier B, Oliver SG, Pallier C, Pascolo S, Pfeiffer F, Philippsen P, Planta RJ, Pohl FM, Pohl TM, P?hlmann R, Portetelle D, Purnelle B, Puzos V, Ramezani Rad M, Rasmussen SW, Remacha M, Revuelta JL, Richard GF, Rieger M, Rodrigues-Pousada C, Rose M, Rupp T, Santos MA, Schwager C, Sensen C, Skala J, Soares H, Sor F, Stegemann J, Tettelin H, Thierry A, Tzermia M, Urrestarazu LA, van Dyck L, Van Vliet-Reedijk JC, Valens M, Vandenbo M, Vilela C, Vissers S, von Wettstein D, Voss H, Wiemann S, Xu G, Zimmermann J, Haasemann M, Becker I, Mewes HW
Nature369(6479)371-8(1994 Jun)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Three highly conserved histidine residues are important for Mrs3p function and mitochondrial iron transport when Mrs (mitochondrial RNA splicing)3p and Mrs4p are inserted into liposomes.
Title: Three conserved histidine residues contribute to mitochondrial iron transport through mitoferrins.
Inner mitochondrial membrane vesicles (SMPs) from the double deletion strain mrs3/4Delta failed to show a rapid Fe(2+) uptake, while SMPs from cells overproducing Mrs3/4p exhibited increased Fe(2+) uptake rates.
Title: The yeast mitochondrial carrier proteins Mrs3p/Mrs4p mediate iron transport across the inner mitochondrial membrane.
defective heme formation in mutants, with a markedly more severe defect in the DeltaDeltaDelta than in the individual Deltamrs3/4 or Deltayfh1 mutants
Title: Frataxin and mitochondrial carrier proteins, Mrs3p and Mrs4p, cooperate in providing iron for heme synthesis.
The following MRS4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MRS4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi03105 | |
Clone ID Related Accession (Same CDS sequence) | NM_001179842.1 | |
Accession Version | NM_001179842.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 915bp) Protein sequence SNP |
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Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | Fe(2+) transporter | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001143). ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGAATACTT CAGAACTGTC AATAGCTGAG GAAATCGACT ACGAAGCTCT TCCATCACAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_012978.1 |
CDS | 1..915 |
Translation |
Target ORF information:
Target ORF information:
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1 | ATGAATACTT CAGAACTGTC AATAGCTGAG GAAATCGACT ACGAAGCTCT TCCATCACAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Life with 6000 genes. |
Complete DNA sequence of yeast chromosome XI. |