SOD1 cDNA ORF clone, Saccharomyces cerevisiae S288C

Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)

Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X.
Galibert F, Alexandraki D, Baur A, Boles E, Chalwatzis N, Chuat JC, Coster F, Cziepluch C, De Haan M, Domdey H, Durand P, Entian KD, Gatius M, Goffeau A, Grivell LA, Hennemann A, Herbert CJ, Heumann K, Hilger F, Hollenberg CP, Huang ME, Jacq C, Jauniaux JC, Katsoulou C, Karpfinger-Hartl L
The EMBO journal15(9)2031-49(1996 May)

propose a model in which Sod1p maximizes Pma1p activity in two ways: one involving signaling through CK1gamma casein kinases and an independent role for Sod1p in oxidative stress protection
Title: Cu/Zn superoxide dismutase and the proton ATPase Pma1p of?Saccharomyces cerevisiae.

analysis of the unusual disulfide bond in copper-zinc superoxide dismutase
Title: Insights into the role of the unusual disulfide bond in copper-zinc superoxide dismutase.

Data indicate that the role of Zn in Cu,Zn-superoxide dismutase SOD1 is structural and also a vital part of the catalytic machinery.
Title: Cu,Zn-superoxide dismutase without Zn is folded but catalytically inactive.

Data indicate that in response to elevated endogenous and exogenous reactive oxygen species (ROS), superoxide dismutase 1 (Sod1) rapidly relocates into the nucleus, which is important for maintaining genomic stability.
Title: Superoxide dismutase 1 acts as a nuclear transcription factor to regulate oxidative stress resistance.

Data show that the aging process increased the DNA damage rates 3-fold in the wild type and more than 5-fold in superoxide dismutases sod1Delta, sod2Delta, and molecular chaperone ccs1Delta mutant cells.
Title: Absence of superoxide dismutase activity causes nuclear DNA fragmentation during the aging process.