Gene Symbol | SMC6 |
Entrez Gene ID | 851099 |
Full Name | DNA repair protein SMC6 |
Synonyms | RHC18 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » SMC6 cDNA ORF clone
Gene Symbol | SMC6 |
Entrez Gene ID | 851099 |
Full Name | DNA repair protein SMC6 |
Synonyms | RHC18 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001182272.1 | NP_013487.1 | DNA repair protein SMC6 |
Eremothecium gossypii | AGOS_AER044W | NP_984904.1 |
LOC699570 | XP_002799197.1 | |
Kluyveromyces lactis | KLLA0E05303g | XP_454184.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_15281 | XP_003716337.1 |
Schizosaccharomyces pombe (fission yeast) | smc6 | NP_587906.1 |
Neurospora crassa | NCU02402 | XP_959722.1 |
Danio rerio (zebrafish) | smc6 | XP_005158646.1 |
Saccharomyces cerevisiae (baker's yeast) | SMC6 | NP_013487.1 |
The nucleotide sequence of Saccharomyces cerevisiae chromosome XII.
Johnston M, Hillier L, Riles L, Albermann K, Andr? B, Ansorge W, Benes V, Br?ckner M, Delius H, Dubois E, D?sterh?ft A, Entian KD, Floeth M, Goffeau A, Hebling U, Heumann K, Heuss-Neitzel D, Hilbert H, Hilger F, Kleine K, K?tter P, Louis EJ, Messenguy F, Mewes HW, Hoheisel JD
Nature387(6632 Suppl)87-90(1997 May)
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
nse3-1/ sir4 Delta double mutants show additive defects for telomere shortening and TPE indicating the contribution of Smc5/6 to telomere homeostasis is only in partial overlap with SIR factor silencing. These findings support a role for Smc5/6 in telomere maintenance that is separate from its canonical role(s) in HR-mediated events during replication and telomere elongation.
Title: Smc5/6 Is a Telomere-Associated Complex that Regulates Sir4 Binding and TPE.
Results show Smc5/6 essential roles and reveal that combined defects in DNA damage tolerance and pausing site-replication cause recombination-mediated DNA lesions.
Title: Essential Roles of the Smc5/6 Complex in Replication through Natural Pausing Sites and Endogenous DNA Damage Tolerance.
The Smc5/6-Mms21 complex operates as a large SUMO ligase in vivo during DNA repair.
Title: ATPase-dependent control of the Mms21 SUMO ligase during DNA repair.
Smc5-Smc6 binds to a Mph1 region required for efficient fork regression, preventing assembly of Mph1 oligomers at the junction of DNA forks.
Title: Restriction of replication fork regression activities by a conserved SMC complex.
The chromosomal association of the Smc5 and Smc6 complex depends on cohesion and predicts the level of sister chromatid entanglement.
Title: The chromosomal association of the Smc5/6 complex depends on cohesion and predicts the level of sister chromatid entanglement.
The following SMC6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SMC6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi00698 | |
Clone ID Related Accession (Same CDS sequence) | NM_001182272.1 | |
Accession Version | NM_001182272.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3345bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | DNA repair protein SMC6 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001144). ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGATTTCGA CTACGATTAG TGGTAAAAGA CCTATAGAGC AGGTTGATGA TGAGCTACTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_013487.1 |
CDS | 1..3345 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001182272.1 |
1 | ATGATTTCGA CTACGATTAG TGGTAAAAGA CCTATAGAGC AGGTTGATGA TGAGCTACTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The nucleotide sequence of Saccharomyces cerevisiae chromosome XII. |
Life with 6000 genes. |