Gene Symbol | dhp1 |
Entrez Gene ID | 2542674 |
Full Name | 5'-3' exoribonuclease Dhp1 |
Gene Type | protein-coding |
Organism | Schizosaccharomyces pombe(fission yeast) |
ORF » Species Summary » Schizosaccharomyces pombe » dhp1 cDNA ORF clone
Gene Symbol | dhp1 |
Entrez Gene ID | 2542674 |
Full Name | 5'-3' exoribonuclease Dhp1 |
Gene Type | protein-coding |
Organism | Schizosaccharomyces pombe(fission yeast) |
mRNA | Protein | Name |
---|---|---|
NM_001019579.2 | NP_594155.1 | 5'-3' exoribonuclease Dhp1 |
Eremothecium gossypii | AGOS_AGR303W | NP_986969.2 |
Pan troglodytes (chimpanzee) | XRN2 | XP_514546.2 |
Canis lupus familiaris (dog) | XRN2 | XP_534324.2 |
Rattus norvegicus (Norway rat) | Xrn2 | NP_001102066.1 |
Drosophila melanogaster (fruit fly) | Rat1 | NP_001260166.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP004090 | XP_309641.5 |
Caenorhabditis elegans (roundworm) | xrn-2 | NP_496958.2 |
Saccharomyces cerevisiae (baker's yeast) | RAT1 | NP_014691.1 |
Xenopus tropicalis (tropical clawed frog) | xrn2 | XP_002939479.1 |
Homo sapiens (human) | XRN2 | NP_036387.2 |
Bos taurus (cattle) | XRN2 | NP_001179401.1 |
Mus musculus (house mouse) | Xrn2 | NP_036047.2 |
Schizosaccharomyces pombe (fission yeast) | dhp1 | NP_594155.1 |
Neurospora crassa | NCU01643 | XP_956265.1 |
XRN2 | XP_001094734.2 | |
Gallus gallus (chicken) | XRN2 | NP_001026204.1 |
Danio rerio (zebrafish) | xrn2 | NP_001001944.2 |
Magnaporthe oryzae (rice blast fungus) | MGG_11426 | XP_003717803.1 |
Kluyveromyces lactis | KLLA0F07469g | XP_455419.1 |
Arabidopsis thaliana (thale cress) | XRN3 | NP_565114.1 |
Oryza sativa (rice) | Os01g0872700 | NP_001044947.1 |
The genome sequence of Schizosaccharomyces pombe.
Wood V, Gwilliam R, Rajandream MA, Lyne M, Lyne R, Stewart A, Sgouros J, Peat N, Hayles J, Baker S, Basham D, Bowman S, Brooks K, Brown D, Brown S, Chillingworth T, Churcher C, Collins M, Connor R, Cronin A, Davis P, Feltwell T, Fraser A, Gentles S, Goble A, Hamlin N, Harris D, Hidalgo J, Hodgson G, Holroyd S, Hornsby T, Howarth S, Huckle EJ, Hunt S, Jagels K, James K, Jones L, Jones M, Leather S, McDonald S, McLean J, Mooney P, Moule S, Mungall K, Murphy L, Niblett D, Odell C, Oliver K, O'Neil S, Pearson D, Quail MA, Rabbinowitsch E, Rutherford K, Rutter S, Saunders D, Seeger K, Sharp S, Skelton J, Simmonds M, Squares R, Squares S, Stevens K, Taylor K, Taylor RG, Tivey A, Walsh S, Warren T, Whitehead S, Woodward J, Volckaert G, Aert R, Robben J, Grymonprez B, Weltjens I, Vanstreels E, Rieger M, Sch?fer M, M?ller-Auer S, Gabel C, Fuchs M, D?sterh?ft A, Fritzc C, Holzer E, Moestl D, Hilbert H, Borzym K, Langer I, Beck A, Lehrach H, Reinhardt R, Pohl TM, Eger P, Zimmermann W, Wedler H, Wambutt R, Purnelle B, Goffeau A, Cadieu E, Dr?ano S, Gloux S, Lelaure V, Mottier S, Galibert F, Aves SJ, Xiang Z, Hunt C, Moore K, Hurst SM, Lucas M, Rochet M, Gaillardin C, Tallada VA, Garzon A, Thode G, Daga RR, Cruzado L, Jimenez J, S?nchez M, del Rey F, Benito J, Dom?nguez A, Revuelta JL, Moreno S, Armstrong J, Forsburg SL, Cerutti L, Lowe T, McCombie WR, Paulsen I, Potashkin J, Shpakovski GV, Ussery D, Barrell BG, Nurse P, Cerrutti L
Nature415(6874)871-80(2002 Feb)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
A function of Pdc2-Lsm1, in concert with Dhp1, regulating RNA by promoting its decapping/destruction in the nucleus of Schizosaccharomyces pombe was suggested.
Title: Involvement of fission yeast Pdc2 in RNA degradation and P-body function.
Dhp1 interacts with the Clr4/Suv39h methyltransferase complex and acts directly to nucleate heterochromatin. Our work uncovers a previously unidentified role for 3'-end processing and transcription termination machinery in gene silencing.
Title: Conserved factor Dhp1/Rat1/Xrn2 triggers premature transcription termination and nucleates heterochromatin to promote gene silencing.
Pac1 and Dhp1p are essential for RNA production and transcript termination.
Title: Pac1 endonuclease and Dhp1p 5'-->3' exonuclease are required for U3 snoRNA termination in Schizosaccharomyces pombe.
The following dhp1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the dhp1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSc103782 | |
Clone ID Related Accession (Same CDS sequence) | NM_001019579.2 | |
Accession Version | NM_001019579.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2976bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-04-02 | |
Organism | Schizosaccharomyces pombe(fission yeast) | |
Product | 5'-3' exoribonuclease Dhp1 | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. This record is derived from an annotated genomic sequence (NC_003424). On Dec 10, 2012 this sequence version replaced NM_001019579.1. |
1 | ATGGGTGTTC CAGCACTTTT CCGCCTTTTG TCGAGGAAAT TCGCAAAGGT CATTACACCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_594155.1 |
CDS | 192..3167 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001019579.2 |
1 | ATGGGTGTTC CAGCACTTTT CCGCCTTTTG TCGAGGAAAT TCGCAAAGGT CATTACACCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The genome sequence of Schizosaccharomyces pombe. |