Gene Symbol | AMELX |
Entrez Gene ID | 396940 |
Full Name | amelogenin, X-linked |
Synonyms | AMEL,LRAP |
Gene Type | protein-coding |
Organism | Sus scrofa(pig) |
Genome |
ORF » Species Summary » Sus scrofa » AMELX cDNA ORF clone
Gene Symbol | AMELX |
Entrez Gene ID | 396940 |
Full Name | amelogenin, X-linked |
Synonyms | AMEL,LRAP |
Gene Type | protein-coding |
Organism | Sus scrofa(pig) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_213906.1 | NP_999071.1 | amelogenin precursor |
XM_021079493.1 | XP_020935152.1 | amelogenin isoform X1 |
Molecular dynamics simulations of the intrinsically disordered protein amelogenin.
Apicella A, Marascio M, Colangelo V, Soncini M, Gautieri A, Plummer CJG
Journal of biomolecular structure & dynamics35(8)1813-1823(2017 Jun)
Dynamic interactions of amelogenin with hydroxyapatite surfaces are dependent on protein phosphorylation and solution pH.
Connelly C, Cicuto T, Leavitt J, Petty A, Litman A, Margolis HC, Gerdon AE
Colloids and surfaces. B, Biointerfaces148377-384(2016 Dec)
Leucine-rich amelogenin peptides regulate mineralization in vitro.
Le Norcy E, Kwak SY, Wiedemann-Bidlack FB, Beniash E, Yamakoshi Y, Simmer JP, Margolis HC
Journal of dental research90(9)1091-7(2011 Sep)
The cooperation of enamelin and amelogenin in controlling octacalcium phosphate crystal morphology.
Fan D, Iijima M, Bromley KM, Yang X, Mathew S, Moradian-Oldak J
Cells, tissues, organs194(2-4)194-8(2011)
Potential role of the amelogenin N-terminus in the regulation of calcium phosphate formation in vitro.
Le Norcy E, Kwak SY, Wiedemann-Bidlack FB, Beniash E, Yamakoshi Y, Simmer JP, Margolis HC
Cells, tissues, organs194(2-4)188-93(2011)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Differences in the viscoelastic properties of phosphorylated amelogenin (P173) and recombinant non-phosphorylated amelogenin (rP172) in the adsorbed state were observed, consistent with noted differences in hydroxyapatite (HAP) binding.
Title: Dynamic interactions of amelogenin with hydroxyapatite surfaces are dependent on protein phosphorylation and solution pH.
Results confirm that the N- and C-termini of amelogenin are conformationally responsive and represent potential interactive sites for amelogenin-target interactions during enamel matrix mineralization.
Title: Probing the self-association, intermolecular contacts, and folding propensity of amelogenin.
The present study provides novel insights into the possible cooperation between enamelin and amelogenin in macromolecular coassembly and in controlling enamel mineral formation.
Title: The cooperation of enamelin and amelogenin in controlling octacalcium phosphate crystal morphology.
The N-terminal domain of amelogenin may play a direct role in early stages of enamel formation.
Title: Potential role of the amelogenin N-terminus in the regulation of calcium phosphate formation in vitro.
Monomeric recombinant porcine rP172 is globally unfolded. Local residual secondary structure [alpha-helix, extended beta-strand, turn/loop, and polyproline type II (PPII)] may serve several functional roles within the enamel matrix.
Title: The tooth enamel protein, porcine amelogenin, is an intrinsically disordered protein with an extended molecular configuration in the monomeric form.
The following AMELX gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the AMELX cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSe00544 | |
Clone ID Related Accession (Same CDS sequence) | NM_213906.1 | |
Accession Version | NM_213906.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 570bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-25 | |
Organism | Sus scrofa(pig) | |
Product | amelogenin precursor | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from U43405.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: U43405.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01048299, SAMN03031511 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGGGACCT GGATTTTGTT TGCTTGCCTC CTGGGAGCAG CCTTCTCTAT GCCTCTACCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_999071.1 |
CDS | 60..629 |
Translation |
Target ORF information:
Target ORF information:
|
NM_213906.1 |
1 | ATGGGGACCT GGATTTTGTT TGCTTGCCTC CTGGGAGCAG CCTTCTCTAT GCCTCTACCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OSe226849 | |
Clone ID Related Accession (Same CDS sequence) | XM_021079493.1 | |
Accession Version | XM_021079493.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 579bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2017-05-12 | |
Organism | Sus scrofa(pig) | |
Product | amelogenin isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_010461.5) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Sus scrofa Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGGGACCT GGATTTTGTT TGCTTGCCTC CTGGGAGCAG CCTTCTCTAT GCCTCTACCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_020935152.1 |
CDS | 596..1174 |
Translation |
Target ORF information:
Target ORF information:
|
XM_021079493.1 |
1 | ATGGGGACCT GGATTTTGTT TGCTTGCCTC CTGGGAGCAG CCTTCTCTAT GCCTCTACCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Molecular dynamics simulations of the intrinsically disordered protein amelogenin. |
Dynamic interactions of amelogenin with hydroxyapatite surfaces are dependent on protein phosphorylation and solution pH. |
Leucine-rich amelogenin peptides regulate mineralization in vitro. |
The cooperation of enamelin and amelogenin in controlling octacalcium phosphate crystal morphology. |
Potential role of the amelogenin N-terminus in the regulation of calcium phosphate formation in vitro. |