FASLG cDNA ORF clone, Sus scrofa(pig)

Gene
Clones
gRNAs

Summary

Gene Symbol	FASLG
Entrez Gene ID	396726
Full Name	Fas ligand (TNF superfamily, member 6)
Synonyms	CD95-L,FASL,TNFSF6
Gene Type	protein-coding
Organism	Sus scrofa(pig)

mRNA and Protein(s)

mRNA	Protein	Name
NM_213806.1	NP_998971.1	tumor necrosis factor ligand superfamily member 6

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Changes in the expression of Fox O1 and death ligand genes during follicular atresia in porcine ovary.
Lin F, Fu YH, Han J, Shen M, Du CW, Li R, Ma XS, Liu HL
Genetics and molecular research : GMR13(3)6638-45(2014 Aug)

Fas Ligand gene transfer enhances the survival of tissue-engineered chondrocyte allografts in mini-pigs.
Xie GH, Wang SJ, Wang Y, Zhang Y, Zhang HZ, Jin S, Wang QF, Liu ZC, Ge HL
Transplant immunology19(2)145-51(2008 May)

The involvement of Fas/FasL interaction in porcine circovirus type 2 and porcine reproductive and respiratory syndrome virus co-inoculation-associated lymphocyte apoptosis in vitro.
Chang HW, Jeng CR, Lin CM, Liu JJ, Chang CC, Tsai YC, Chia MY, Pang VF
Veterinary microbiology122(1-2)72-82(2007 May)

Differential gene expression in endometrium, endometrial lymphocytes, and trophoblasts during successful and abortive embryo implantation.
Tayade C, Black GP, Fang Y, Croy BA
Journal of immunology (Baltimore, Md. : 1950)176(1)148-56(2006 Jan)

Expression of Fas but not Fas ligand on fetal pig beta cells.
Bai L, Maedler K, Donath M, Tuch BE
Xenotransplantation11(5)426-35(2004 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Data suggest forkhead box protein O1 (FoxO1) involvement in the regulation of TNF-related apoptosis-inducing ligand TRAIL and Fas ligand FasL expression during follicular atresia.
Title: Changes in the expression of Fox O1 and death ligand genes during follicular atresia in porcine ovary.

the result indicates that the expression of FasL by chondrocytes is capable of inducing apoptosis of activated T cells
Title: Fas Ligand gene transfer enhances the survival of tissue-engineered chondrocyte allografts in mini-pigs.

The expression of FAS and FAS ligand in splenic macrophages co-infected with porcine circovirus 2 and porcine reproductive and respiratory syndrome virus is reported
Title: The involvement of Fas/FasL interaction in porcine circovirus type 2 and porcine reproductive and respiratory syndrome virus co-inoculation-associated lymphocyte apoptosis in vitro.

FasL was not detected on fetal pig pancreatic cells but could be induced on both beta and non-beta cells when the cells were treated with IL1beta.
Title: Expression of Fas but not Fas ligand on fetal pig beta cells.

The following FASLG gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the FASLG cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OSe00223	NM_213806.1 Latest version!	Sus scrofa Fas ligand (TNF superfamily, member 6) (FASLG), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

FASLG ( NM_213806.1 ) cDNA ORF clone, Sus scrofa(pig) -> NP_998971.1 Sus scrofa Fas ligand (TNF superfamily, member 6) (FASLG), mRNA.

Price & Availability↑

CloneID	OSe00223
Clone ID Related Accession (Same CDS sequence)	NM_213806.1
Accession Version	NM_213806.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 849bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-23
Organism	Sus scrofa(pig)
Product	tumor necrosis factor ligand superfamily member 6
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AB027297.1. ##Evidence-Data-START## Transcript exon combination :: AB027297.1, AF397407.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01893940, SAMN01915393 [ECO:0000348] ##Evidence-Data-END##

ATGCAGCAGC CCTTCAATTA CCCATACCCC CAAATCTTCT GGGTGGACAG CAGTGCTACC 
TCTCCCTGGG CCTCCCCAGG CTCAGTCTTC CCCTGTCCAG CTTCTGTGCC AGGAAGGCCA 
GGGCAAAGGA GGCCACCACC ACCACCGCCG CCACCGCCAC CACCACCAAC ACTCCTGCCA 
TCAAGACCGC TGCCTCCACT GCCACCGCCA TCTCTGAAGA AGAAGAGGGA CCACAATGCA 
GGCCTGTGTC TCCTTGTGAT GTTCTTCATG GTTCTGGTGG CCCTGGTTGG ATTGGGGCTG 
GGGATGTTTC AGCTCTTCCA CCTACAGAAG GAGCTGACTG AACTCAGAGA GTCTGCCAGC 
CAAAGGCATA CAGAATCATC TTTGGAGAAG CAAATAGGTC ACCCCAATCT ACCCTCTGAG 
AAAAAGGAGC TGAGAAAAGT GGCCCACTTA ACAGGCAAGC CTAACTCAAG ATCCATCCCT 
CTGGAATGGG AAGACACCTA TGGAATTGCC TTGGTCTCTG GGGTGAAGTA TATGAAGGGC 
AGCCTTGTGA TCAATGACAC TGGGCTGTAT TTTGTGTATT CCAAAGTGTA CTTCCGGGGT 
CAGTACTGCA ACAACCAGCC CCTGAGTCAC AAGGTATACA CAAGGAACTC TAGGTATCCC 
CAGGACCTGG TGCTGATGGA GGGAAAGATG ATGAACTATT GCACTACTGG CCAAATGTGG 
GCCCGCAGCA GCTACCTGGG GGCTGTGTTC AATCTCACCA GCGCTGACCA TTTATATGTC 
AACGTATCTG AGCTCTCTCT GGTCAATTTT GAGGAATCTA AGACATTTTT TGGCTTATAT 
AAGCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_998971.1
CDS	1..849
Translation	MQQPFNYPYPQIFWVDSSATSPWASPGSVFPCPASVPGRPGQRRPPPPPPPPPPPPTLLPSRPLPPLPPPSLKKKRDHNAGLCLLVMFFMVLVALVGLGLGMFQLFHLQKELTELRESASQRHTESSLEKQIGHPNLPSEKKELRKVAHLTGKPNSRSIPLEWEDTYGIALVSGVKYMKGSLVINDTGLYFVYSKVYFRGQYCNNQPLSHKVYTRNSRYPQDLVLMEGKMMNYCTTGQMWARSSYLGAVFNLTSADHLYVNVSELSLVNFEESKTFFGLYKL

Target ORF information:

RefSeq Version	NM_213806.1
Organism	Sus scrofa(pig)
Definition	Sus scrofa Fas ligand (TNF superfamily, member 6) (FASLG), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_213806.1

ORF Insert Sequence:

ATGCAGCAGC CCTTCAATTA CCCATACCCC CAAATCTTCT GGGTGGACAG CAGTGCTACC 
TCTCCCTGGG CCTCCCCAGG CTCAGTCTTC CCCTGTCCAG CTTCTGTGCC AGGAAGGCCA 
GGGCAAAGGA GGCCACCACC ACCACCGCCG CCACCGCCAC CACCACCAAC ACTCCTGCCA 
TCAAGACCGC TGCCTCCACT GCCACCGCCA TCTCTGAAGA AGAAGAGGGA CCACAATGCA 
GGCCTGTGTC TCCTTGTGAT GTTCTTCATG GTTCTGGTGG CCCTGGTTGG ATTGGGGCTG 
GGGATGTTTC AGCTCTTCCA CCTACAGAAG GAGCTGACTG AACTCAGAGA GTCTGCCAGC 
CAAAGGCATA CAGAATCATC TTTGGAGAAG CAAATAGGTC ACCCCAATCT ACCCTCTGAG 
AAAAAGGAGC TGAGAAAAGT GGCCCACTTA ACAGGCAAGC CTAACTCAAG ATCCATCCCT 
CTGGAATGGG AAGACACCTA TGGAATTGCC TTGGTCTCTG GGGTGAAGTA TATGAAGGGC 
AGCCTTGTGA TCAATGACAC TGGGCTGTAT TTTGTGTATT CCAAAGTGTA CTTCCGGGGT 
CAGTACTGCA ACAACCAGCC CCTGAGTCAC AAGGTATACA CAAGGAACTC TAGGTATCCC 
CAGGACCTGG TGCTGATGGA GGGAAAGATG ATGAACTATT GCACTACTGG CCAAATGTGG 
GCCCGCAGCA GCTACCTGGG GGCTGTGTTC AATCTCACCA GCGCTGACCA TTTATATGTC 
AACGTATCTG AGCTCTCTCT GGTCAATTTT GAGGAATCTA AGACATTTTT TGGCTTATAT 
AAGCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Changes in the expression of Fox O1 and death ligand genes during follicular atresia in porcine ovary.
Genetics and molecular research : GMR13(3)6638-45(2014 Aug)
Lin F,Fu YH,Han J,Shen M,Du CW,Li R,Ma XS,Liu HL

Fas Ligand gene transfer enhances the survival of tissue-engineered chondrocyte allografts in mini-pigs.
Transplant immunology19(2)145-51(2008 May)
Xie GH,Wang SJ,Wang Y,Zhang Y,Zhang HZ,Jin S,Wang QF,Liu ZC,Ge HL

The involvement of Fas/FasL interaction in porcine circovirus type 2 and porcine reproductive and respiratory syndrome virus co-inoculation-associated lymphocyte apoptosis in vitro.
Veterinary microbiology122(1-2)72-82(2007 May)
Chang HW,Jeng CR,Lin CM,Liu JJ,Chang CC,Tsai YC,Chia MY,Pang VF

Differential gene expression in endometrium, endometrial lymphocytes, and trophoblasts during successful and abortive embryo implantation.
Journal of immunology (Baltimore, Md. : 1950)176(1)148-56(2006 Jan)
Tayade C,Black GP,Fang Y,Croy BA

Expression of Fas but not Fas ligand on fetal pig beta cells.
Xenotransplantation11(5)426-35(2004 Sep)
Bai L,Maedler K,Donath M,Tuch BE