| Gene Symbol | F2 |
| Entrez Gene ID | 100144442 |
| Full Name | coagulation factor II, thrombin |
| Gene Type | protein-coding |
| Organism | Sus scrofa(pig) |
| Genome |
The following F2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the F2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OSe00813 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001122985.1 | |
| Accession Version | NM_001122985.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1872bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-02-17 | |
| Organism | Sus scrofa(pig) | |
| Product | prothrombin precursor | |
| Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from DQ530370.1. ##Evidence-Data-START## Transcript exon combination :: DQ530370.1, EF692642.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN02584787 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGGCGCACG TCGGAGGCCT GTGGCTTCAT GGCTGCTTGG CCCTGGCTGT CCTCGTTAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001116457.1 |
| CDS | 17..1888 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_001122985.1 |
1 | ATGGCGCACG TCGGAGGCCT GTGGCTTCAT GGCTGCTTGG CCCTGGCTGT CCTCGTTAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OSe242386 | |
| Clone ID Related Accession (Same CDS sequence) | XM_021076838.1 | |
| Accession Version | XM_021076838.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1755bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2017-05-12 | |
| Organism | Sus scrofa(pig) | |
| Product | prothrombin isoform X1 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_010444.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Sus scrofa Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGGCGCACG TCGGAGGCCT GTGGCTTCCT GGCTGCTTGG CCCTGGCTGT CCTCGTTAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_020932497.1 |
| CDS | 37..1791 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_021076838.1 |
1 | ATGGCGCACG TCGGAGGCCT GTGGCTTCCT GGCTGCTTGG CCCTGGCTGT CCTCGTTAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Thrombin stimulates smooth muscle cell differentiation from peripheral blood mononuclear cells via protease-activated receptor-1, RhoA, and myocardin. |
Thrombin stimulates mitogenesis in pig cerebrovascular smooth muscle cells involving activation of pro-matrix metalloproteinase-2. |
Pig thrombomodulin binds human thrombin but is a poor cofactor for activation of human protein C and TAFI. |
cDNA cloning, protein structure modeling of rhesus monkey (Macaca mulatta) prothrombin. |
Regulation of transglutaminase activity in articular chondrocytes through thrombin receptor-mediated factor XIII synthesis. |
