Gene Symbol | tor1 |
Entrez Gene ID | 2540473 |
Full Name | phosphatidylinositol kinase Tor1 |
Gene Type | protein-coding |
Organism | Schizosaccharomyces pombe(fission yeast) |
ORF » Species Summary » Schizosaccharomyces pombe » tor1 cDNA ORF clone
Gene Symbol | tor1 |
Entrez Gene ID | 2540473 |
Full Name | phosphatidylinositol kinase Tor1 |
Gene Type | protein-coding |
Organism | Schizosaccharomyces pombe(fission yeast) |
mRNA | Protein | Name |
---|---|---|
NM_001022196.2 | NP_596275.1 | phosphatidylinositol kinase Tor1 |
The genome sequence of Schizosaccharomyces pombe.
Wood V, Gwilliam R, Rajandream MA, Lyne M, Lyne R, Stewart A, Sgouros J, Peat N, Hayles J, Baker S, Basham D, Bowman S, Brooks K, Brown D, Brown S, Chillingworth T, Churcher C, Collins M, Connor R, Cronin A, Davis P, Feltwell T, Fraser A, Gentles S, Goble A, Hamlin N, Harris D, Hidalgo J, Hodgson G, Holroyd S, Hornsby T, Howarth S, Huckle EJ, Hunt S, Jagels K, James K, Jones L, Jones M, Leather S, McDonald S, McLean J, Mooney P, Moule S, Mungall K, Murphy L, Niblett D, Odell C, Oliver K, O'Neil S, Pearson D, Quail MA, Rabbinowitsch E, Rutherford K, Rutter S, Saunders D, Seeger K, Sharp S, Skelton J, Simmonds M, Squares R, Squares S, Stevens K, Taylor K, Taylor RG, Tivey A, Walsh S, Warren T, Whitehead S, Woodward J, Volckaert G, Aert R, Robben J, Grymonprez B, Weltjens I, Vanstreels E, Rieger M, Sch?fer M, M?ller-Auer S, Gabel C, Fuchs M, D?sterh?ft A, Fritzc C, Holzer E, Moestl D, Hilbert H, Borzym K, Langer I, Beck A, Lehrach H, Reinhardt R, Pohl TM, Eger P, Zimmermann W, Wedler H, Wambutt R, Purnelle B, Goffeau A, Cadieu E, Dr?ano S, Gloux S, Lelaure V, Mottier S, Galibert F, Aves SJ, Xiang Z, Hunt C, Moore K, Hurst SM, Lucas M, Rochet M, Gaillardin C, Tallada VA, Garzon A, Thode G, Daga RR, Cruzado L, Jimenez J, S?nchez M, del Rey F, Benito J, Dom?nguez A, Revuelta JL, Moreno S, Armstrong J, Forsburg SL, Cerutti L, Lowe T, McCombie WR, Paulsen I, Potashkin J, Shpakovski GV, Ussery D, Barrell BG, Nurse P, Cerrutti L
Nature415(6874)871-80(2002 Feb)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Since Gaf1 was also critical for transcription of per1+ and put4+, Tor-Gaf1 signaling may coordinate transcription of multiple amino acid permeases according to nutrient availability
Title: Tor Signaling Regulates Transcription of Amino Acid Permeases through a GATA Transcription Factor Gaf1 in Fission Yeast.
The Gad8 kinase (AKT homologue) phosphorylates fission yeast Tor1 at threonine (T1972) to reduce activity.
Title: Phosphorylation of the TOR ATP binding domain by AGC kinase constitutes a novel mode of TOR inhibition.
While mutated TORC1 and TORC2 displayed diminished kinase activity and FKBP12/Fkh1-dependent rapamycin sensitivity, their phenotypes were nearly opposite in mitosis.
Title: The reverse, but coordinated, roles of Tor2 (TORC1) and Tor1 (TORC2) kinases for growth, cell cycle and separase-mediated mitosis in Schizosaccharomyces pombe.
Data highlight critical roles for TORC2 and its component Tor1 in chromatin metabolism and in promoting mitotic entry, most notably after recovery from DNA-damaging conditions.
Title: TOR complex 2 controls gene silencing, telomere length maintenance, and survival under DNA-damaging conditions.
Results suggest that S. pombe Tor1 and Tor2 can both act in TORC1, but it is the inhibition of Tor1 as part of TORC1 that promotes mitosis following nutrient stress.
Title: Fission yeast Tor1 functions as part of TORC1 to control mitotic entry through the stress MAPK pathway following nutrient stress.
The following tor1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the tor1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSc100283 | |
Clone ID Related Accession (Same CDS sequence) | NM_001022196.2 | |
Accession Version | NM_001022196.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 7008bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-04-02 | |
Organism | Schizosaccharomyces pombe(fission yeast) | |
Product | phosphatidylinositol kinase Tor1 | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. This record is derived from an annotated genomic sequence (NC_003423). On Dec 10, 2012 this sequence version replaced NM_001022196.1. |
1 | ATGGAGTATT TTAGTGATCT AAAAAACAAA AATGAAAGCA TTCAACTAGC AGCCGCTGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_596275.1 |
CDS | 200..7207 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001022196.2 |
1 | ATGGAGTATT TTAGTGATCT AAAAAACAAA AATGAAAGCA TTCAACTAGC AGCCGCTGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The genome sequence of Schizosaccharomyces pombe. |