Gene Symbol | asp1 |
Entrez Gene ID | 2539244 |
Full Name | inositol hexakisphosphate kinase/inositol pyrophosphate synthase (predicted) |
Gene Type | protein-coding |
Organism | Schizosaccharomyces pombe(fission yeast) |
ORF » Species Summary » Schizosaccharomyces pombe » asp1 cDNA ORF clone
Gene Symbol | asp1 |
Entrez Gene ID | 2539244 |
Full Name | inositol hexakisphosphate kinase/inositol pyrophosphate synthase (predicted) |
Gene Type | protein-coding |
Organism | Schizosaccharomyces pombe(fission yeast) |
mRNA | Protein | Name |
---|---|---|
NM_001022869.2 | NP_587877.1 | putative inositol hexakisphosphate kinase/inositol pyrophosphate synthase |
Kluyveromyces lactis | KLLA0B02805g | XP_451657.1 |
Schizosaccharomyces pombe (fission yeast) | asp1 | NP_587877.1 |
Saccharomyces cerevisiae (baker's yeast) | VIP1 | NP_013514.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_06039 | XP_003711888.1 |
Eremothecium gossypii | AGOS_AER082W | NP_984942.1 |
Neurospora crassa | NCU07010 | XP_961831.2 |
The genome sequence of Schizosaccharomyces pombe.
Wood V, Gwilliam R, Rajandream MA, Lyne M, Lyne R, Stewart A, Sgouros J, Peat N, Hayles J, Baker S, Basham D, Bowman S, Brooks K, Brown D, Brown S, Chillingworth T, Churcher C, Collins M, Connor R, Cronin A, Davis P, Feltwell T, Fraser A, Gentles S, Goble A, Hamlin N, Harris D, Hidalgo J, Hodgson G, Holroyd S, Hornsby T, Howarth S, Huckle EJ, Hunt S, Jagels K, James K, Jones L, Jones M, Leather S, McDonald S, McLean J, Mooney P, Moule S, Mungall K, Murphy L, Niblett D, Odell C, Oliver K, O'Neil S, Pearson D, Quail MA, Rabbinowitsch E, Rutherford K, Rutter S, Saunders D, Seeger K, Sharp S, Skelton J, Simmonds M, Squares R, Squares S, Stevens K, Taylor K, Taylor RG, Tivey A, Walsh S, Warren T, Whitehead S, Woodward J, Volckaert G, Aert R, Robben J, Grymonprez B, Weltjens I, Vanstreels E, Rieger M, Sch?fer M, M?ller-Auer S, Gabel C, Fuchs M, D?sterh?ft A, Fritzc C, Holzer E, Moestl D, Hilbert H, Borzym K, Langer I, Beck A, Lehrach H, Reinhardt R, Pohl TM, Eger P, Zimmermann W, Wedler H, Wambutt R, Purnelle B, Goffeau A, Cadieu E, Dr?ano S, Gloux S, Lelaure V, Mottier S, Galibert F, Aves SJ, Xiang Z, Hunt C, Moore K, Hurst SM, Lucas M, Rochet M, Gaillardin C, Tallada VA, Garzon A, Thode G, Daga RR, Cruzado L, Jimenez J, S?nchez M, del Rey F, Benito J, Dom?nguez A, Revuelta JL, Moreno S, Armstrong J, Forsburg SL, Cerutti L, Lowe T, McCombie WR, Paulsen I, Potashkin J, Shpakovski GV, Ussery D, Barrell BG, Nurse P, Cerrutti L
Nature415(6874)871-80(2002 Feb)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Study provides evidence that Asp1 kinase function is needed for the execution of all three stages of mitosis and controls bipolar spindle stability, chromosome biorientation, and the fidelity of chromosome transmission in Schizosaccharomyces pombe.
Title: Inositol Pyrophosphate Kinase Asp1 Modulates Chromosome Segregation Fidelity and Spindle Function in Schizosaccharomyces pombe.
Biochemical and mutagenic studies demonstrated that the [2Fe-2S](2+) cluster substantially inhibits the phosphatase activity of Asp1, thereby increasing its net kinase activity.
Title: Asp1 from Schizosaccharomyces pombe binds a [2Fe-2S](2+) cluster which inhibits inositol pyrophosphate 1-phosphatase activity.
Translin binds the pre-mRNA-splicing factor srp1 and vip1, a protein conserved in fungi.
Title: Identification of proteins that form specific complexes with the highly conserved protein Translin in Schizosaccharomyces pombe.
Data show that the S. pombe Asp1 protein, a member of the conserved Vip1 1/3 inositol polyphosphate kinase family, is a key regulator of the morphological switch via the cAMP protein kinase A (PKA) pathway.
Title: Asp1, a conserved 1/3 inositol polyphosphate kinase, regulates the dimorphic switch in Schizosaccharomyces pombe.
Vip1 and Asp1 acted as enzymes that encode inositol hexakisphosphate (IP6) and inositol heptakisphosphate (IP7) kinase activities; the functionality of Asp1 and Vip1 may provide cells with increased signaling capacity through metabolism of IP6
Title: A conserved family of enzymes that phosphorylate inositol hexakisphosphate.
The following asp1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the asp1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSc99319 | |
Clone ID Related Accession (Same CDS sequence) | NM_001022869.2 | |
Accession Version | NM_001022869.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2763bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-04-02 | |
Organism | Schizosaccharomyces pombe(fission yeast) | |
Product | putative inositol hexakisphosphate kinase/inositol pyrophosphate synthase | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. This record is derived from an annotated genomic sequence (NC_003421). On Dec 10, 2012 this sequence version replaced NM_001022869.1. |
1 | ATGATTCAAA ATGCAAGTCA TCTTACATCT ATCGACACAG AGTCATCTAC CAGAACGGCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_587877.1 |
CDS | 91..2853 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001022869.2 |
1 | ATGATTCAAA ATGCAAGTCA TCTTACATCT ATCGACACAG AGTCATCTAC CAGAACGGCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The genome sequence of Schizosaccharomyces pombe. |