Gene Symbol | VPS4 |
Entrez Gene ID | 856303 |
Full Name | AAA family ATPase VPS4 |
Synonyms | CSC1,DID6,END13,GRD13,VPL4,VPT10 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » VPS4 cDNA ORF clone
Gene Symbol | VPS4 |
Entrez Gene ID | 856303 |
Full Name | AAA family ATPase VPS4 |
Synonyms | CSC1,DID6,END13,GRD13,VPL4,VPT10 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001184270.1 | NP_015499.1 | AAA family ATPase VPS4 |
Oryza sativa (rice) | Os01g0141100 | NP_001041983.1 |
Homo sapiens (human) | VPS4B | NP_004860.2 |
Canis lupus familiaris (dog) | VPS4B | XP_005615402.1 |
Eremothecium gossypii | AGOS_AEL265W | NP_984595.1 |
Xenopus tropicalis (tropical clawed frog) | vps4b | NP_001011154.1 |
Rattus norvegicus (Norway rat) | Vps4b | NP_001020887.1 |
Gallus gallus (chicken) | VPS4B | NP_001006378.2 |
Caenorhabditis elegans (roundworm) | vps-4 | NP_490816.4 |
Schizosaccharomyces pombe (fission yeast) | vps4 | NP_593086.1 |
Pan troglodytes (chimpanzee) | VPS4B | XP_523954.2 |
VPS4B | XP_002801004.1 | |
Bos taurus (cattle) | VPS4B | NP_001069624.1 |
Neurospora crassa | NCU06942 | XP_958048.1 |
Arabidopsis thaliana (thale cress) | SKD1 | NP_180328.1 |
Mus musculus (house mouse) | Vps4b | NP_033216.2 |
Danio rerio (zebrafish) | vps4b | NP_957200.1 |
Saccharomyces cerevisiae (baker's yeast) | VPS4 | NP_015499.1 |
Kluyveromyces lactis | KLLA0B10846g | XP_452011.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_07916 | XP_003713158.1 |
The nucleotide sequence of Saccharomyces cerevisiae chromosome XVI.
Bussey H, Storms RK, Ahmed A, Albermann K, Allen E, Ansorge W, Araujo R, Aparicio A, Barrell B, Badcock K, Benes V, Botstein D, Bowman S, Br?ckner M, Carpenter J, Cherry JM, Chung E, Churcher C, Coster F, Davis K, Davis RW, Dietrich FS, Delius H, DiPaolo T, Hani J
Nature387(6632 Suppl)103-5(1997 May)
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The major ESCRT-III subunit Snf7 localizes transiently to vesicles and tubules surrounded by a cup-shaped membrane and this was accelerated in vps4Delta cells, correlating with increased Acb1 secretion.
Title: ESCRT-III drives the final stages of CUPS maturation for unconventional protein secretion.
data support a model in which Ist1-Did2 interactions during ESCRT-III polymerization coordinate Vps4 activity with the timing of ESCRT-III disassembly
Title: Conformational Changes in the Endosomal Sorting Complex Required for the Transport III Subunit Ist1 Lead to Distinct Modes of ATPase Vps4 Regulation.
These data support a mechanism in which Vps4 disassembles its substrates by completely unfolding them and threading them through the central pore.
Title: Vps4 disassembles an ESCRT-III filament by global unfolding and processive translocation.
Data implicate the ESCRT machinery in preventing the formation of nonfunctional nuclear pore complexes (NPCs); authors propose a model in which ESCRT-III/Vps4 helps recognize and clear defective NPC assembly intermediates before a step in which they are committed to maturing into a malformed NPC destined for the storage of improperly assembled nuclear pore complexes compar
Title: Surveillance of nuclear pore complex assembly by ESCRT-III/Vps4.
Binding of Vps4 to ESCRT-III, coordinated by interactions with Vps2 and Snf7, is coupled to membrane neck constriction during intraluminal vesicle formation.
Title: Coordinated binding of Vps4 to ESCRT-III drives membrane neck constriction during MVB vesicle formation.
The following VPS4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the VPS4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi05119 | |
Clone ID Related Accession (Same CDS sequence) | NM_001184270.1 | |
Accession Version | NM_001184270.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1314bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | AAA family ATPase VPS4 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001148). ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGAGCACGG GAGATTTTTT AACTAAGGGA ATAGAACTGG TTCAAAAGGC CATTGACCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_015499.1 |
CDS | 1..1314 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001184270.1 |
1 | ATGAGCACGG GAGATTTTTT AACTAAGGGA ATAGAACTGG TTCAAAAGGC CATTGACCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The nucleotide sequence of Saccharomyces cerevisiae chromosome XVI. |
Life with 6000 genes. |