Gene Symbol | GPB2 |
Entrez Gene ID | 851243 |
Full Name | Gpb2p |
Synonyms | KRH1 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » GPB2 cDNA ORF clone
Gene Symbol | GPB2 |
Entrez Gene ID | 851243 |
Full Name | Gpb2p |
Synonyms | KRH1 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001178199.2 | NP_009345.3 | Gpb2p |
Kluyveromyces lactis | KLLA0F00374g | XP_455096.1 |
Saccharomyces cerevisiae (baker's yeast) | GPB2 | NP_009345.3 |
Saccharomyces cerevisiae (baker's yeast) | GPB1 | NP_015016.3 |
Eremothecium gossypii | AGOS_ADR414C | NP_984509.1 |
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
The nucleotide sequence of chromosome I from Saccharomyces cerevisiae.
Bussey H, Kaback DB, Zhong W, Vo DT, Clark MW, Fortin N, Hall J, Ouellette BF, Keng T, Barton AB
Proceedings of the National Academy of Sciences of the United States of America92(9)3809-13(1995 Apr)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Gpb1 and Gpb2 oppose PKA activity by blocking the ability of PKA to inhibit Bcy1 phosphorylation
Title: Nutrient control of yeast PKA activity involves opposing effects on phosphorylation of the Bcy1 regulatory subunit.
Gpa2 relieves the inhibition imposed by the kelch-repeat proteins on Protein Kinase A (PKA), thereby bypassing adenylate cyclase for direct regulation of PKA.
Title: Kelch-repeat proteins interacting with the Galpha protein Gpa2 bypass adenylate cyclase for direct regulation of protein kinase A in yeast.
Gpb1/2 bind to a conserved C-terminal domain of Ira1/2, and loss of Gpb1/2 results in a destabilization of Ira1 and Ira2, leading to elevated levels of Ras2-GTP and unbridled cAMP-PKA signaling.
Title: The kelch proteins Gpb1 and Gpb2 inhibit Ras activity via association with the yeast RasGAP neurofibromin homologs Ira1 and Ira2.
The following GPB2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the GPB2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi00825 | |
Clone ID Related Accession (Same CDS sequence) | NM_001178199.2 | |
Accession Version | NM_001178199.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2643bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | Gpb2p | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001133). On Apr 26, 2011 this sequence version replaced NM_001178199.1. ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGGAAATTT CCAGTTCACC ATGGAACGAC GGTGGATACA GCCCCTATGA GAGAAACAGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_009345.3 |
CDS | 1..2643 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001178199.2 |
1 | ATGGAAATTT CCAGTTCACC ATGGAACGAC GGTGGATACA GCCCCTATGA GAGAAACAGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Life with 6000 genes. |
The nucleotide sequence of chromosome I from Saccharomyces cerevisiae. |