Gene Symbol | TLG2 |
Entrez Gene ID | 854142 |
Full Name | Tlg2p |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » TLG2 cDNA ORF clone
Gene Symbol | TLG2 |
Entrez Gene ID | 854142 |
Full Name | Tlg2p |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001183272.1 | NP_014624.1 | Tlg2p |
STX16 | XP_002798124.1 | |
Bos taurus (cattle) | STX16 | XP_002692463.1 |
Danio rerio (zebrafish) | stx16 | XP_691316.2 |
Caenorhabditis elegans (roundworm) | syn-16 | NP_498105.1 |
Saccharomyces cerevisiae (baker's yeast) | TLG2 | NP_014624.1 |
Homo sapiens (human) | STX16 | NP_001001433.1 |
Canis lupus familiaris (dog) | STX16 | XP_005635285.1 |
Mus musculus (house mouse) | Stx16 | NP_766263.2 |
Arabidopsis thaliana (thale cress) | SYP42 | NP_567223.1 |
Drosophila melanogaster (fruit fly) | Syx16 | NP_523420.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_06883 | XP_003709612.1 |
Pan troglodytes (chimpanzee) | STX16 | XP_514749.2 |
Rattus norvegicus (Norway rat) | Stx16 | NP_001102080.1 |
Gallus gallus (chicken) | STX16 | NP_001006295.1 |
Eremothecium gossypii | AGOS_AEL026C | NP_984835.2 |
Arabidopsis thaliana (thale cress) | SYP41 | NP_001031950.1 |
Xenopus tropicalis (tropical clawed frog) | LOC100493473 | XP_002943756.2 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP000850 | XP_316820.5 |
Kluyveromyces lactis | KLLA0A10681g | XP_451467.1 |
Schizosaccharomyces pombe (fission yeast) | tlg2 | NP_593832.1 |
Neurospora crassa | NCU04119 | XP_961275.2 |
Arabidopsis thaliana (thale cress) | SYP43 | NP_566256.1 |
The nucleotide sequence of Saccharomyces cerevisiae chromosome XV.
Dujon B, Albermann K, Aldea M, Alexandraki D, Ansorge W, Arino J, Benes V, Bohn C, Bolotin-Fukuhara M, Bordonn? R, Boyer J, Camasses A, Casamayor A, Casas C, Ch?ret G, Cziepluch C, Daignan-Fornier B, Dang DV, de Haan M, Delius H, Durand P, Fairhead C, Feldmann H, Gaillon L, Kleine K
Nature387(6632 Suppl)98-102(1997 May)
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
secretion of enolase ENO2 is inhibited in a TLG2 knockout mutant.
Title: Tracing putative trafficking of the glycolytic enzyme enolase via SNARE-driven unconventional secretion.
Data show that the SM protein Vps45p, which regulates endosomal trafficking in yeast, binds the conserved N-terminal peptide of the syntaxin Tlg2p.
Title: The N-terminal peptide of the syntaxin Tlg2p modulates binding of its closed conformation to Vps45p.
Data support a model in which the Sec1p/Munc18 protein is required to facilitate a switch of Tlg2p and Sx16 from a closed to an open conformation, thus allowing SNARE-complex assembly and membrane fusion to proceed.
Title: Functional homology of mammalian syntaxin 16 and yeast Tlg2p reveals a conserved regulatory mechanism.
Disruption of this high-affinity binding between Vps45p and Tlg2p leads to downregulation of Tlg2p.
Title: Cellular levels of the syntaxin Tlg2p are regulated by a single mode of binding to Vps45p.
The following TLG2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TLG2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi03298 | |
Clone ID Related Accession (Same CDS sequence) | NM_001183272.1 | |
Accession Version | NM_001183272.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1194bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | Tlg2p | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001147). ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGTTTAGAG ATAGAACTAA TTTATTTTTA TCATACCGTA GGACTTTCCC TCATAACATA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_014624.1 |
CDS | 1..1194 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001183272.1 |
1 | ATGTTTAGAG ATAGAACTAA TTTATTTTTA TCATACCGTA GGACTTTCCC TCATAACATA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The nucleotide sequence of Saccharomyces cerevisiae chromosome XV. |
Life with 6000 genes. |