Gene Symbol | CRM1 |
Entrez Gene ID | 853133 |
Full Name | exportin CRM1 |
Synonyms | KAP124,XPO1 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » CRM1 cDNA ORF clone
Gene Symbol | CRM1 |
Entrez Gene ID | 853133 |
Full Name | exportin CRM1 |
Synonyms | KAP124,XPO1 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001181347.3 | NP_011734.3 | exportin CRM1 |
XPO1 | XP_001115623.1 | |
Mus musculus (house mouse) | Xpo1 | NP_001030303.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP009929 | XP_319051.2 |
Saccharomyces cerevisiae (baker's yeast) | CRM1 | NP_011734.3 |
Eremothecium gossypii | AGOS_ADL128C | NP_983968.2 |
Neurospora crassa | NCU01820 | XP_955917.2 |
Arabidopsis thaliana (thale cress) | XPO1B | NP_566193.2 |
Arabidopsis thaliana (thale cress) | XPO1A | NP_197204.1 |
Oryza sativa (rice) | Os03g0858100 | NP_001051959.1 |
Bos taurus (cattle) | XPO1 | NP_001179190.1 |
Kluyveromyces lactis | KLLA0E16061g | XP_454672.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_02526 | XP_003709336.1 |
Rattus norvegicus (Norway rat) | Xpo1 | NP_445942.1 |
Drosophila melanogaster (fruit fly) | emb | NP_723391.2 |
Homo sapiens (human) | XPO1 | NP_003391.1 |
Danio rerio (zebrafish) | xpo1b | XP_001919797.3 |
Caenorhabditis elegans (roundworm) | xpo-1 | NP_741567.1 |
Xenopus tropicalis (tropical clawed frog) | xpo1 | XP_002939551.2 |
Pan troglodytes (chimpanzee) | XPO1 | XP_515727.2 |
Canis lupus familiaris (dog) | XPO1 | XP_005626195.1 |
Gallus gallus (chicken) | XPO1 | NP_001012887.2 |
Schizosaccharomyces pombe (fission yeast) | crm1 | XP_001713070.1 |
The nucleotide sequence of Saccharomyces cerevisiae chromosome VII.
Tettelin H, Agostoni Carbone ML, Albermann K, Albers M, Arroyo J, Backes U, Barreiros T, Bertani I, Bjourson AJ, Br?ckner M, Bruschi CV, Carignani G, Castagnoli L, Cerdan E, Clemente ML, Coblenz A, Coglievina M, Coissac E, Defoor E, Del Bino S, Delius H, Delneri D, de Wergifosse P, Dujon B, Kleine K
Nature387(6632 Suppl)81-4(1997 May)
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The exportin Crm1 is also required for the same pre-ribosome maturation events that involve Rrp12. Thus, in addition to their implication in nuclear export, Rrp12 and Crm1 participate in earlier biosynthetic steps that take place in the nucleolus.
Title: Rrp12 and the Exportin Crm1 participate in late assembly events in the nucleolus during 40S ribosomal subunit biogenesis.
The structure shows that on association of Ran-binding domain (RanBD) of RanBP1 with CRM1:NES-cargo:RanGTP complex, RanBD and the C-terminal acidic tail of Ran induce a large movement of the intra-HEAT9 loop of CRM1.
Title: An allosteric mechanism to displace nuclear export cargo from CRM1 and RanGTP by RanBP1.
Hxk2 phosphorylation at serine 14 promotes Hxk2 export by facilitating the association of Hxk2 with Xpo1.
Title: Nuclear export of the yeast hexokinase 2 protein requires the Xpo1 (Crm1)-dependent pathway.
A functional link between Xpo1 and the spindle pole body and a role for this exportin in spindle biogenesis in budding yeast, is proposed.
Title: Nuclear export receptor Xpo1/Crm1 is physically and functionally linked to the spindle pole body in budding yeast.
In the daughter cell nucleus Cbk1p phosphorylates the Ace2p nuclear export signal, and the phosphorylation blocks the export of Ace2p via Crm1p.
Title: Mutations in a small region of the exportin Crm1p disrupt the daughter cell-specific nuclear localization of the transcription factor Ace2p in Saccharomyces cerevisiae.
The following CRM1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CRM1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi02436 | |
Clone ID Related Accession (Same CDS sequence) | NM_001181347.3 | |
Accession Version | NM_001181347.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3255bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | exportin CRM1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001139). On Jul 30, 2012 this sequence version replaced NM_001181347.2. ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGGAAGGAA TTTTGGATTT TTCTAACGAC TTAGATATCG CTCTATTAGA TCAGGTGGTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_011734.3 |
CDS | 1..3255 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001181347.3 |
1 | ATGGAAGGAA TTTTGGATTT TTCTAACGAC TTAGATATCG CTCTATTAGA TCAGGTGGTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The nucleotide sequence of Saccharomyces cerevisiae chromosome VII. |
Life with 6000 genes. |