Gene Symbol | GET3 |
Entrez Gene ID | 851458 |
Full Name | guanine nucleotide exchange factor GET3 |
Synonyms | ARR4 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » GET3 cDNA ORF clone
Gene Symbol | GET3 |
Entrez Gene ID | 851458 |
Full Name | guanine nucleotide exchange factor GET3 |
Synonyms | ARR4 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001180159.1 | NP_010183.1 | guanine nucleotide exchange factor GET3 |
Kluyveromyces lactis | KLLA0E01497g | XP_454016.1 |
Canis lupus familiaris (dog) | ASNA1 | XP_533904.2 |
Drosophila melanogaster (fruit fly) | CG1598 | NP_610296.2 |
Anopheles gambiae (African malaria mosquito) | ASNA_ANOGA | XP_556439.3 |
Saccharomyces cerevisiae (baker's yeast) | GET3 | NP_010183.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_09535 | XP_003712205.1 |
Arabidopsis thaliana (thale cress) | AT1G01910 | NP_849575.1 |
Pan troglodytes (chimpanzee) | ASNA1 | XP_512413.3 |
Mus musculus (house mouse) | Asna1 | NP_062626.1 |
Caenorhabditis elegans (roundworm) | asna-1 | NP_498965.1 |
Neurospora crassa | NCU06717 | XP_960897.1 |
Bos taurus (cattle) | ASNA1 | NP_001092334.1 |
Rattus norvegicus (Norway rat) | Asna1 | NP_001093975.1 |
Eremothecium gossypii | AGOS_ADR285W | NP_984381.2 |
Oryza sativa (rice) | Os09g0521500 | NP_001063707.1 |
Homo sapiens (human) | ASNA1 | NP_004308.2 |
Danio rerio (zebrafish) | asna1 | NP_001002298.1 |
Schizosaccharomyces pombe (fission yeast) | get3 | NP_594270.1 |
Xenopus tropicalis (tropical clawed frog) | asna1 | XP_004915513.1 |
The nucleotide sequence of Saccharomyces cerevisiae chromosome IV.
Jacq C, Alt-M?rbe J, Andre B, Arnold W, Bahr A, Ballesta JP, Bargues M, Baron L, Becker A, Biteau N, Bl?cker H, Blugeon C, Boskovic J, Brandt P, Br?ckner M, Buitrago MJ, Coster F, Delaveau T, del Rey F, Dujon B, Eide LG, Garcia-Cantalejo JM, Goffeau A, Gomez-Peris A, Zaccaria P
Nature387(6632 Suppl)75-8(1997 May)
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Get3 functions as a redox-regulated chaperone, effectively protecting eukaryotic cells against oxidative protein damage.
Title: The protein targeting factor Get3 functions as ATP-independent chaperone under oxidative stress conditions.
The crystal structure of the Get3-Get4-Get5 complex in an ATP-bound state is presented.
Title: Crystal structure of ATP-bound Get3-Get4-Get5 complex reveals regulation of Get3 by Get4.
ATP specifically induces multiple conformational changes in Get3 that culminate in its ATPase activation through tetramerization
Title: Precise timing of ATPase activation drives targeting of tail-anchored proteins.
Get3 moves reversibly to deposition sites for protein aggregates, hence supporting the sequestration of tail-anchored proteins under conditions that prevent tail-anchored protein insertion.
Title: Get3 is a holdase chaperone and moves to deposition sites for aggregated proteins when membrane targeting is blocked.
Get1 uses two interfaces to stabilize the open dimer conformation of Get3.
Title: Get1 stabilizes an open dimer conformation of get3 ATPase by binding two distinct interfaces.
The following GET3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the GET3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi01006 | |
Clone ID Related Accession (Same CDS sequence) | NM_001180159.1 | |
Accession Version | NM_001180159.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1065bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | guanine nucleotide exchange factor GET3 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001136). ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGGATTTAA CCGTGGAACC TAATTTGCAC TCTTTAATTA CCTCTACCAC TCATAAGTGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_010183.1 |
CDS | 1..1065 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001180159.1 |
1 | ATGGATTTAA CCGTGGAACC TAATTTGCAC TCTTTAATTA CCTCTACCAC TCATAAGTGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The nucleotide sequence of Saccharomyces cerevisiae chromosome IV. |
Life with 6000 genes. |