Col3a1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Col3a1
Entrez Gene ID	84032
Full Name	collagen type III alpha 1 chain
General protein information	Preferred Names collagen type III alpha 1 chain Names collagen alpha-1(III) chain collagen, type III, alpha 1 procollagen, type III, alpha 1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 9 Map Location: 9q22
Summary	may be involved in craniofacial development [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_032085.1	NP_114474.1	collagen alpha-1(III) chain precursor

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Col3a1	NP_114474.1
	COL3A1	XP_001105968.2
Mus musculus (house mouse)	Col3a1	NP_034060.2
Homo sapiens (human)	COL3A1	NP_000081.1
Pan troglodytes (chimpanzee)	COL3A1	XP_001163809.1
Gallus gallus (chicken)	COL3A1	NP_990711.2
Xenopus tropicalis (tropical clawed frog)	col3a1	NP_001136379.1

Gene Ontology
Bibliography

Related articles in PubMed

Pin1 facilitates isoproterenol?induced cardiac fibrosis and collagen deposition by promoting oxidative stress and activating the MEK1/2?ERK1/2 signal transduction pathway in rats.
Wu X, Li M, Chen SQ, Li S, Guo F
International journal of molecular medicine41(3)1573-1583(2018 Mar)

Dexmedetomidine Protects PC12 Cells from Lidocaine-Induced Cytotoxicity Through Downregulation of COL3A1 Mediated by miR-let-7b.
Wang Q, She Y, Bi X, Zhao B, Ruan X, Tan Y
DNA and cell biology36(7)518-528(2017 Jul)

Urinary collagen degradation products as early markers of progressive renal fibrosis.
Hijmans RS, Rasmussen DG, Yazdani S, Navis G, van Goor H, Karsdal MA, Genovese F, van den Born J
Journal of translational medicine15(1)63(2017 Mar)

Glycoproteomics Reveals Decorin Peptides With Anti-Myostatin Activity in Human Atrial Fibrillation.
Barallobre-Barreiro J, Gupta SK, Zoccarato A, Kitazume-Taneike R, Fava M, Yin X, Werner T, Hirt MN, Zampetaki A, Viviano A, Chong M, Bern M, Kourliouros A, Domenech N, Willeit P, Shah AM, Jahangiri M, Schaefer L, Fischer JW, Iozzo RV, Viner R, Thum T, Heineke J, Kichler A, Otsu K, Mayr M
Circulation134(11)817-32(2016 Sep)

[Down-regulation of p38 MAPK and collagen by 1, 25-(OH)2-VD3 in rat models of diabetic nephropathy].
Xie X, Li Z, Pi M, Wu J, Zeng W, Zuo L, Zha Y
Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology32(7)931-5(2016 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

miR-let-7b and COL3A1 might play critical roles in neuronal injury, they are potential therapeutic targets.
Title: Dexmedetomidine Protects PC12 Cells from Lidocaine-Induced Cytotoxicity Through Downregulation of COL3A1 Mediated by miR-let-7b.

the diagnostic value of urinary collagen degradation products in a proteinuria-driven fibrosis rat model, was investigated.
Title: Urinary collagen degradation products as early markers of progressive renal fibrosis.

Data show that collagen type III (Col3), collagen type IV (Col4) and p38 mitogen-activated protein kinase (p38 MAPK) are up-regulated in models of diabetic nephropathy.
Title: [Down-regulation of p38 MAPK and collagen by 1, 25-(OH)2-VD3 in rat models of diabetic nephropathy].

High Collagen Type III expression is associated with renal fibrosis in experimental kidney diseases.
Title: Serum and urine markers of collagen degradation reflect renal fibrosis in experimental kidney diseases.

The mRNA and protein content of collagen I, collagen III and elastin in the abdominal aorta (AA) and femoral artery (FA) was investigated in Wistar-Kyoto rats.
Title: Physiological regulation of extracellular matrix collagen and elastin in the arterial wall of rats by noradrenergic tone and angiotensin II.

The following Col3a1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Col3a1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa09022	NM_032085.1 Latest version!	Rattus norvegicus collagen type III alpha 1 chain (Col3a1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$727.30 $1039.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Col3a1 ( NM_032085.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_114474.1 Rattus norvegicus collagen type III alpha 1 chain (Col3a1), mRNA.

Price & Availability↑

CloneID	ORa09022
Clone ID Related Accession (Same CDS sequence)	NM_032085.1
Accession Version	NM_032085.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4392bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-25
Organism	Rattus norvegicus(Norway rat)
Product	collagen alpha-1(III) chain precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC087039.1. On Dec 20, 2004 this sequence version replaced XM_343563.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC087039.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2689595, SAMEA2689596 [ECO:0000348] ##Evidence-Data-END##

ATGATGAGCT TTGTGCAATG TGGGACCTGG TTTCTTCTCA CCCTGCTTCA CCCCTCTCTT 
ATTTTGGCAC AGCAGTCCAA TGTAGATGAA TTGGGATGCA ACTACCTTGG TCAGTCCTAT 
GAGTCTAGAG ATGTCTGGAA GCCAGAACCA TGTCAAATAT GTGTCTGCGA CTCGGGATCT 
GTCCTCTGTG ATGACATAAT GTGTGATGAT GAGCCACTAG ACTGCCCCAA CCCAGAGATC 
CCATTTGGAG AATGTTGTGC AATATGTCCA CAGCCTTCTA CACCTGCTCC TGTCATTCCT 
GATGGTAATA GACCTCAAGG CCCCAAGGGA GATCCAGGCC CTCCTGGCAT TCCTGGGAGA 
AATGGCGACC CTGGTCTTCC AGGACAACCA GGGCTCCCTG GTCCTCCTGG CTCCCCTGGA 
ATCTGTGAAT CATGTCCAAC TGGTGGCCAG AATTATTCTC CCCAATTCGA CTCATATGAT 
GTCAAGTCTG GAGTCGGAGG AATGGGTGGC TATCCTGGAC CAGCTGGTCC ACCAGGCCCT 
CCAGGACCCC CTGGTTCCTC TGGACATCCT GGATCTCCTG GTTCTCCTGG ATACCAAGGT 
CCTCCTGGTG AACCGGGTCA AGCTGGTCCT GCAGGCCCTC CAGGACCTCC TGGTGCTATT 
GGTCCATCTG GCCCTGCAGG AAAGGATGGA GAGTCAGGAA GACCCGGACG ACCTGGAGAG 
CGTGGACTGC CTGGACCTCC AGGTATCAAA GGCCCAGCTG GTATCCCTGG ATTCCCGGGT 
ATGAAAGGAC ACAGAGGCTT TGATGGACGC AATGGAGAGA AGGGTGAAAC CGGTGCTCCT 
GGATTGAAGG GTGAAAACGG TCTTCCGGGA GACAACGGAG CTCCTGGCCC CATGGGTCCC 
AGAGGGGCTC CTGGTGAGCG AGGACGACCA GGTCTTCCTG GAGCCGCAGG TGCTCGAGGC 
AATGATGGTG CTCGGGGCAG TGACGGGCAA CCAGGTCCCC CTGGTCCTCC TGGAACTGCA 
GGATTCCCTG GATCTCCTGG TGCTAAGGGT GAGGTTGGAC CTGCAGGATC CCCTGGCTCA 
AATGGCTCTC CAGGACAAAG AGGGGAACCT GGACCACAAG GACACGCTGG TGCTCAAGGA 
CCTCCTGGCC CTCCTGGCAA TAATGGCAGT CCTGGTGGGA AAGGTGAAAT GGGTCCAGCT 
GGCATTCCTG GAGCTCCTGG ACTCCTAGGA GCTAGGGGTC CCCCTGGACC AGCAGGAGCT 
AATGGTGCAC CGGGACAACG AGGTCCTTCA GGCGAACCGG GCAAGAATGG AGCAAAGGGA 
GAGCCAGGAG CTCGCGGTGA ACGGGGCGAA GCTGGTTCCC CAGGGATTCC AGGACCTAAG 
GGCGAAGACG GCAAAGATGG GTCACCAGGA GAACCTGGTG CAAATGGAGT TCCAGGAAAC 
CCAGGAGAAA GGGGTGCCCC TGGCTTCCGA GGACCTGCAG GGCCAAATGG CGCCCCAGGA 
GAAAAGGGTC CTGCTGGAGA GCGTGGTGGC CCAGGTCCTG CAGGACCTAG AGGAGTAGCT 
GGAGAACCTG GCCGAGATGG AACCCCTGGA GGTCCAGGGA TACGGGGTAT GCCCGGAAGT 
CCAGGTGGAC CAGGCAATGA TGGGAAACCA GGACCTCCTG GAAGTCAAGG AGAAAGTGGT 
CGCCCTGGTC CTCCTGGCCC ATCTGGCCCC AGAGGTCAGC CTGGTGTCAT GGGTTTCCCT 
GGTCCTAAAG GAAATGATGG TGCACCTGGC AAAAACGGAG AACGGGGTGG CCCTGGGGGT 
CCTGGCCTTC CAGGTCCTGC TGGAAAGAAT GGGGAGACTG GACCTCAGGG TCCCCCAGGA 
CCTACTGGCG CACCTGGTGA CAAGGGAGAC GCTGGACCCC CTGGTCCACA AGGATTACAA 
GGCATACCTG GTACCAGTGG TCCTCCAGGA GAAAATGGAA AACCAGGAGA ACCAGGTCCA 
AAGGGTGAAG CTGGAGCACC TGGAGTTCCT GGAGGCAAGG GTGATTCTGG TGCCCCTGGA 
GAACGTGGAC CCCCTGGAAC CGCAGGAACC CCTGGGCTTA GAGGTGGAGC TGGACCCCCT 
GGGCCTGAGG GAGGAAAGGG CCCTGCTGGT CCCCCTGGTC CCCCTGGTAC TTCTGGTCCT 
CCTGGTCTGC AAGGGATGCC AGGAGAGAGA GGAGGTCCTG GGAGTCCTGG CCCAAAGGGT 
GAAAAGGGTG AGCCAGGCGG TGCGGGTGCT GATGGAGTTC CAGGAAAGGA TGGGCCGAGA 
GGTCCTGCTG GTCCTATTGG TCCCCCTGGC CCAGCTGGTC AGCCTGGAGA TAAGGGTGAA 
GGTGGTGCCC CTGGACTTCC AGGTATAGCT GGACCTCGAG GTGGCCCTGG TGAGAGAGGT 
GAACATGGCC CTCCAGGACC TGCTGGCTTC CCGGGTGCTC CTGGGCAGAA TGGTGAACCA 
GGTGCTAAAG GAGAAAGAGG TGCCCCCGGA GAGAAAGGTG AAGGAGGCCC TCCTGGTGCC 
GCAGGACCCC CTGGTGGTTC TGGACCTGCT GGTCCTCCTG GGCCTCAAGG TGTAAAGGGT 
GAACGGGGCA GTCCTGGCGG TCCTGGTGCT GCTGGCTTTC CCGGTGGCCG TGGTCTTCCT 
GGTCCTCCCG GCAACAATGG TAATCCAGGG CCCCCAGGAC CCAGTGGTGC TCCTGGCAAG 
GATGGCCCTC CAGGTCCTGC AGGTAACAGT GGTTCTCCTG GAAACCCTGG AGTAGCTGGA 
CCAAAAGGTG ATGCTGGCCA ACCAGGAGAG AAGGGGCCAC CTGGTGCTCA GGGTCCTCCA 
GGATCTCCAG GTCCACTTGG AATTGCAGGG CTAACTGGAG CACGAGGTCT TGCTGGACCA 
CCAGGCATGC CAGGTCCACG GGGTAGCCCT GGACCTCAGG GTATCAAGGG TGAAAGTGGA 
AAGCCAGGAG CCAGTGGCCA TAATGGGGAA CGTGGTCCTC CTGGACCCCA AGGTCTTCCT 
GGTCAGCCTG GTACAGCTGG TGAGCCCGGA AGGGATGGAA ACCCTGGATC AGATGGTCAG 
CCAGGTCGAG ACGGATCTCC TGGTGGCAAG GGTGATCGTG GTGAAAATGG TTCTCCTGGT 
GCCCCAGGCG CTCCTGGTCA TCCAGGACCA CCTGGTCCTG TTGGTCCATC TGGAAAAAAT 
GGTGACAGAG GAGAAACGGG TCCTGCTGGT CCTTCTGGTG CTCCAGGTCC TGCTGGAGCT 
CGGGGTGCTC CTGGTCCCCA AGGTCCACGA GGTGACAAAG GTGAAACTGG TGAACGTGGC 
TCTAATGGCA TCAAAGGACA TCGAGGATTC CCTGGCAATC CAGGTCCCCC AGGTTCTCCC 
GGTGCTGCTG GACACCAGGG TGCAGTTGGT AGTCCAGGCC CTGCAGGTCC CAGAGGCCCA 
GTTGGTCCAC ATGGACCTCC TGGAAAAGAT GGATCAAGTG GACATCCAGG TCCCATTGGA 
CCACCAGGGC CTCGAGGTAA CAGAGGTGAA AGAGGATCTG AGGGCTCGCC CGGTCACCCT 
GGACAGCCAG GACCCCCTGG ACCCCCTGGT GCCCCTGGTC CCTGCTGTGG TGGCGGTGCT 
GCCATTGCTG GAGTTGGAGG TGAAAAGTCT GGCGGCTTTT CACCATATTA CGGGGATGAT 
CCAATGGATT TCAAGATCAA CACTGAGGAG ATCATGTCTT CACTCAAGTC TGTTAACGGA 
CAAATAGAGA GTCTTATCAG CCCTGATGGT TCTAGAAAAA ACCCTGCTCG GAATTGCAGA 
GACCTGAAAT TCTGCCACCC TGAACTCAAG AGCGGAGAAT ACTGGGTTGA TCCTAACCAA 
GGCTGCAAGA TGGATGCTAT AAAAGTGTTC TGTAATATGG AAACCGGAGA AACATGCATA 
AATGCCAGTC CCATGACTGT CCCGCGGAAG CACTGGTGGA CAGATGCTGG TGCTGAGAAG 
AAACATGTTT GGTTTGGAGA ATCTATGAAT GGTGGCTTTC AGTTCAGCTA TGGCAATCCT 
GATCTTCCTG AAGATGTCCT TGATGTACAG CTGGCCTTCC TCAGACTTCT TTCCAGCCGG 
GCCTCCCAGA ACATTACATA CCACTGCAAA AACAGCATTG CCTACATGGA TCAGGCCAAT 
GGCAATGTAA AGAAGTCTCT GAAGCTGATG GGATCCAATG AGGGAGAATT CAAGGCTGAA 
GGAAATAGCA AATTCACTTA CACAGTTCTA GAGGATGGCT GCACTAAACA CACTGGTGAA 
TGGAGCAAGA CAGTCTTTGA ATATCAAACA CGCAAGGCCA TGAGACTCCC CATCATAGAT 
ATCGCACCCT ATGACATTGG TGGTCCTGAT CAAGAATTTG GTGTGGACAT TGGCCCTGTT 
TGCTTTTTAT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_114474.1
CDS	105..4496
Translation	MMSFVQCGTWFLLTLLHPSLILAQQSNVDELGCNYLGQSYESRDVWKPEPCQICVCDSGSVLCDDIMCDDEPLDCPNPEIPFGECCAICPQPSTPAPVIPDGNRPQGPKGDPGPPGIPGRNGDPGLPGQPGLPGPPGSPGICESCPTGGQNYSPQFDSYDVKSGVGGMGGYPGPAGPPGPPGPPGSSGHPGSPGSPGYQGPPGEPGQAGPAGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGDNGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGSPGQRGEPGPQGHAGAQGPPGPPGNNGSPGGKGEMGPAGIPGAPGLLGARGPPGPAGANGAPGQRGPSGEPGKNGAKGEPGARGERGEAGSPGIPGPKGEDGKDGSPGEPGANGVPGNPGERGAPGFRGPAGPNGAPGEKGPAGERGGPGPAGPRGVAGEPGRDGTPGGPGIRGMPGSPGGPGNDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGLPGPAGKNGETGPQGPPGPTGAPGDKGDAGPPGPQGLQGIPGTSGPPGENGKPGEPGPKGEAGAPGVPGGKGDSGAPGERGPPGTAGTPGLRGGAGPPGPEGGKGPAGPPGPPGTSGPPGLQGMPGERGGPGSPGPKGEKGEPGGAGADGVPGKDGPRGPAGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGGPGERGEHGPPGPAGFPGAPGQNGEPGAKGERGAPGEKGEGGPPGAAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGGRGLPGPPGNNGNPGPPGPSGAPGKDGPPGPAGNSGSPGNPGVAGPKGDAGQPGEKGPPGAQGPPGSPGPLGIAGLTGARGLAGPPGMPGPRGSPGPQGIKGESGKPGASGHNGERGPPGPQGLPGQPGTAGEPGRDGNPGSDGQPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPSGKNGDRGETGPAGPSGAPGPAGARGAPGPQGPRGDKGETGERGSNGIKGHRGFPGNPGPPGSPGAAGHQGAVGSPGPAGPRGPVGPHGPPGKDGSSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPGAPGPCCGGGAAIAGVGGEKSGGFSPYYGDDPMDFKINTEEIMSSLKSVNGQIESLISPDGSRKNPARNCRDLKFCHPELKSGEYWVDPNQGCKMDAIKVFCNMETGETCINASPMTVPRKHWWTDAGAEKKHVWFGESMNGGFQFSYGNPDLPEDVLDVQLAFLRLLSSRASQNITYHCKNSIAYMDQANGNVKKSLKLMGSNEGEFKAEGNSKFTYTVLEDGCTKHTGEWSKTVFEYQTRKAMRLPIIDIAPYDIGGPDQEFGVDIGPVCFL

Target ORF information:

RefSeq Version	NM_032085.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus collagen type III alpha 1 chain (Col3a1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_032085.1

ORF Insert Sequence:

ATGATGAGCT TTGTGCAATG TGGGACCTGG TTTCTTCTCA CCCTGCTTCA CCCCTCTCTT 
ATTTTGGCAC AGCAGTCCAA TGTAGATGAA TTGGGATGCA ACTACCTTGG TCAGTCCTAT 
GAGTCTAGAG ATGTCTGGAA GCCAGAACCA TGTCAAATAT GTGTCTGCGA CTCGGGATCT 
GTCCTCTGTG ATGACATAAT GTGTGATGAT GAGCCACTAG ACTGCCCCAA CCCAGAGATC 
CCATTTGGAG AATGTTGTGC AATATGTCCA CAGCCTTCTA CACCTGCTCC TGTCATTCCT 
GATGGTAATA GACCTCAAGG CCCCAAGGGA GATCCAGGCC CTCCTGGCAT TCCTGGGAGA 
AATGGCGACC CTGGTCTTCC AGGACAACCA GGGCTCCCTG GTCCTCCTGG CTCCCCTGGA 
ATCTGTGAAT CATGTCCAAC TGGTGGCCAG AATTATTCTC CCCAATTCGA CTCATATGAT 
GTCAAGTCTG GAGTCGGAGG AATGGGTGGC TATCCTGGAC CAGCTGGTCC ACCAGGCCCT 
CCAGGACCCC CTGGTTCCTC TGGACATCCT GGATCTCCTG GTTCTCCTGG ATACCAAGGT 
CCTCCTGGTG AACCGGGTCA AGCTGGTCCT GCAGGCCCTC CAGGACCTCC TGGTGCTATT 
GGTCCATCTG GCCCTGCAGG AAAGGATGGA GAGTCAGGAA GACCCGGACG ACCTGGAGAG 
CGTGGACTGC CTGGACCTCC AGGTATCAAA GGCCCAGCTG GTATCCCTGG ATTCCCGGGT 
ATGAAAGGAC ACAGAGGCTT TGATGGACGC AATGGAGAGA AGGGTGAAAC CGGTGCTCCT 
GGATTGAAGG GTGAAAACGG TCTTCCGGGA GACAACGGAG CTCCTGGCCC CATGGGTCCC 
AGAGGGGCTC CTGGTGAGCG AGGACGACCA GGTCTTCCTG GAGCCGCAGG TGCTCGAGGC 
AATGATGGTG CTCGGGGCAG TGACGGGCAA CCAGGTCCCC CTGGTCCTCC TGGAACTGCA 
GGATTCCCTG GATCTCCTGG TGCTAAGGGT GAGGTTGGAC CTGCAGGATC CCCTGGCTCA 
AATGGCTCTC CAGGACAAAG AGGGGAACCT GGACCACAAG GACACGCTGG TGCTCAAGGA 
CCTCCTGGCC CTCCTGGCAA TAATGGCAGT CCTGGTGGGA AAGGTGAAAT GGGTCCAGCT 
GGCATTCCTG GAGCTCCTGG ACTCCTAGGA GCTAGGGGTC CCCCTGGACC AGCAGGAGCT 
AATGGTGCAC CGGGACAACG AGGTCCTTCA GGCGAACCGG GCAAGAATGG AGCAAAGGGA 
GAGCCAGGAG CTCGCGGTGA ACGGGGCGAA GCTGGTTCCC CAGGGATTCC AGGACCTAAG 
GGCGAAGACG GCAAAGATGG GTCACCAGGA GAACCTGGTG CAAATGGAGT TCCAGGAAAC 
CCAGGAGAAA GGGGTGCCCC TGGCTTCCGA GGACCTGCAG GGCCAAATGG CGCCCCAGGA 
GAAAAGGGTC CTGCTGGAGA GCGTGGTGGC CCAGGTCCTG CAGGACCTAG AGGAGTAGCT 
GGAGAACCTG GCCGAGATGG AACCCCTGGA GGTCCAGGGA TACGGGGTAT GCCCGGAAGT 
CCAGGTGGAC CAGGCAATGA TGGGAAACCA GGACCTCCTG GAAGTCAAGG AGAAAGTGGT 
CGCCCTGGTC CTCCTGGCCC ATCTGGCCCC AGAGGTCAGC CTGGTGTCAT GGGTTTCCCT 
GGTCCTAAAG GAAATGATGG TGCACCTGGC AAAAACGGAG AACGGGGTGG CCCTGGGGGT 
CCTGGCCTTC CAGGTCCTGC TGGAAAGAAT GGGGAGACTG GACCTCAGGG TCCCCCAGGA 
CCTACTGGCG CACCTGGTGA CAAGGGAGAC GCTGGACCCC CTGGTCCACA AGGATTACAA 
GGCATACCTG GTACCAGTGG TCCTCCAGGA GAAAATGGAA AACCAGGAGA ACCAGGTCCA 
AAGGGTGAAG CTGGAGCACC TGGAGTTCCT GGAGGCAAGG GTGATTCTGG TGCCCCTGGA 
GAACGTGGAC CCCCTGGAAC CGCAGGAACC CCTGGGCTTA GAGGTGGAGC TGGACCCCCT 
GGGCCTGAGG GAGGAAAGGG CCCTGCTGGT CCCCCTGGTC CCCCTGGTAC TTCTGGTCCT 
CCTGGTCTGC AAGGGATGCC AGGAGAGAGA GGAGGTCCTG GGAGTCCTGG CCCAAAGGGT 
GAAAAGGGTG AGCCAGGCGG TGCGGGTGCT GATGGAGTTC CAGGAAAGGA TGGGCCGAGA 
GGTCCTGCTG GTCCTATTGG TCCCCCTGGC CCAGCTGGTC AGCCTGGAGA TAAGGGTGAA 
GGTGGTGCCC CTGGACTTCC AGGTATAGCT GGACCTCGAG GTGGCCCTGG TGAGAGAGGT 
GAACATGGCC CTCCAGGACC TGCTGGCTTC CCGGGTGCTC CTGGGCAGAA TGGTGAACCA 
GGTGCTAAAG GAGAAAGAGG TGCCCCCGGA GAGAAAGGTG AAGGAGGCCC TCCTGGTGCC 
GCAGGACCCC CTGGTGGTTC TGGACCTGCT GGTCCTCCTG GGCCTCAAGG TGTAAAGGGT 
GAACGGGGCA GTCCTGGCGG TCCTGGTGCT GCTGGCTTTC CCGGTGGCCG TGGTCTTCCT 
GGTCCTCCCG GCAACAATGG TAATCCAGGG CCCCCAGGAC CCAGTGGTGC TCCTGGCAAG 
GATGGCCCTC CAGGTCCTGC AGGTAACAGT GGTTCTCCTG GAAACCCTGG AGTAGCTGGA 
CCAAAAGGTG ATGCTGGCCA ACCAGGAGAG AAGGGGCCAC CTGGTGCTCA GGGTCCTCCA 
GGATCTCCAG GTCCACTTGG AATTGCAGGG CTAACTGGAG CACGAGGTCT TGCTGGACCA 
CCAGGCATGC CAGGTCCACG GGGTAGCCCT GGACCTCAGG GTATCAAGGG TGAAAGTGGA 
AAGCCAGGAG CCAGTGGCCA TAATGGGGAA CGTGGTCCTC CTGGACCCCA AGGTCTTCCT 
GGTCAGCCTG GTACAGCTGG TGAGCCCGGA AGGGATGGAA ACCCTGGATC AGATGGTCAG 
CCAGGTCGAG ACGGATCTCC TGGTGGCAAG GGTGATCGTG GTGAAAATGG TTCTCCTGGT 
GCCCCAGGCG CTCCTGGTCA TCCAGGACCA CCTGGTCCTG TTGGTCCATC TGGAAAAAAT 
GGTGACAGAG GAGAAACGGG TCCTGCTGGT CCTTCTGGTG CTCCAGGTCC TGCTGGAGCT 
CGGGGTGCTC CTGGTCCCCA AGGTCCACGA GGTGACAAAG GTGAAACTGG TGAACGTGGC 
TCTAATGGCA TCAAAGGACA TCGAGGATTC CCTGGCAATC CAGGTCCCCC AGGTTCTCCC 
GGTGCTGCTG GACACCAGGG TGCAGTTGGT AGTCCAGGCC CTGCAGGTCC CAGAGGCCCA 
GTTGGTCCAC ATGGACCTCC TGGAAAAGAT GGATCAAGTG GACATCCAGG TCCCATTGGA 
CCACCAGGGC CTCGAGGTAA CAGAGGTGAA AGAGGATCTG AGGGCTCGCC CGGTCACCCT 
GGACAGCCAG GACCCCCTGG ACCCCCTGGT GCCCCTGGTC CCTGCTGTGG TGGCGGTGCT 
GCCATTGCTG GAGTTGGAGG TGAAAAGTCT GGCGGCTTTT CACCATATTA CGGGGATGAT 
CCAATGGATT TCAAGATCAA CACTGAGGAG ATCATGTCTT CACTCAAGTC TGTTAACGGA 
CAAATAGAGA GTCTTATCAG CCCTGATGGT TCTAGAAAAA ACCCTGCTCG GAATTGCAGA 
GACCTGAAAT TCTGCCACCC TGAACTCAAG AGCGGAGAAT ACTGGGTTGA TCCTAACCAA 
GGCTGCAAGA TGGATGCTAT AAAAGTGTTC TGTAATATGG AAACCGGAGA AACATGCATA 
AATGCCAGTC CCATGACTGT CCCGCGGAAG CACTGGTGGA CAGATGCTGG TGCTGAGAAG 
AAACATGTTT GGTTTGGAGA ATCTATGAAT GGTGGCTTTC AGTTCAGCTA TGGCAATCCT 
GATCTTCCTG AAGATGTCCT TGATGTACAG CTGGCCTTCC TCAGACTTCT TTCCAGCCGG 
GCCTCCCAGA ACATTACATA CCACTGCAAA AACAGCATTG CCTACATGGA TCAGGCCAAT 
GGCAATGTAA AGAAGTCTCT GAAGCTGATG GGATCCAATG AGGGAGAATT CAAGGCTGAA 
GGAAATAGCA AATTCACTTA CACAGTTCTA GAGGATGGCT GCACTAAACA CACTGGTGAA 
TGGAGCAAGA CAGTCTTTGA ATATCAAACA CGCAAGGCCA TGAGACTCCC CATCATAGAT 
ATCGCACCCT ATGACATTGG TGGTCCTGAT CAAGAATTTG GTGTGGACAT TGGCCCTGTT 
TGCTTTTTAT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Pin1 facilitates isoproterenol?induced cardiac fibrosis and collagen deposition by promoting oxidative stress and activating the MEK1/2?ERK1/2 signal transduction pathway in rats.
International journal of molecular medicine41(3)1573-1583(2018 Mar)
Wu X,Li M,Chen SQ,Li S,Guo F

Dexmedetomidine Protects PC12 Cells from Lidocaine-Induced Cytotoxicity Through Downregulation of COL3A1 Mediated by miR-let-7b.
DNA and cell biology36(7)518-528(2017 Jul)
Wang Q,She Y,Bi X,Zhao B,Ruan X,Tan Y

Urinary collagen degradation products as early markers of progressive renal fibrosis.
Journal of translational medicine15(1)63(2017 Mar)
Hijmans RS,Rasmussen DG,Yazdani S,Navis G,van Goor H,Karsdal MA,Genovese F,van den Born J

Glycoproteomics Reveals Decorin Peptides With Anti-Myostatin Activity in Human Atrial Fibrillation.
Circulation134(11)817-32(2016 Sep)
Barallobre-Barreiro J,Gupta SK,Zoccarato A,Kitazume-Taneike R,Fava M,Yin X,Werner T,Hirt MN,Zampetaki A,Viviano A,Chong M,Bern M,Kourliouros A,Domenech N,Willeit P,Shah AM,Jahangiri M,Schaefer L,Fischer JW,Iozzo RV,Viner R,Thum T,Heineke J,Kichler A,Otsu K,Mayr M

[Down-regulation of p38 MAPK and collagen by 1, 25-(OH)2-VD3 in rat models of diabetic nephropathy].
Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology32(7)931-5(2016 Jul)
Xie X,Li Z,Pi M,Wu J,Zeng W,Zuo L,Zha Y

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Col3a1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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