Casp6 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Casp6
Entrez Gene ID	83584
Full Name	caspase 6
Synonyms	Mch2
General protein information	Preferred Names caspase 6 Names caspase-6 CASP-6 apoptotic protease Mch-2
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 2 Map Location: 2q43
Summary	member of the cysteine-aspartic acid protease (caspase) family that plays a terminal role in apoptosis [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_001271984.1	NP_001258913.1	caspase-6
XM_017591135.1	XP_017446624.1	caspase-6 isoform X1
XM_008761528.2	XP_008759750.1	caspase-6 isoform X1
NM_031775.3	NP_113963.2	caspase-6

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Casp6	NP_033941.3
Bos taurus (cattle)	CASP6	NP_001030496.1
Gallus gallus (chicken)	CASP6	NP_990057.1
Xenopus tropicalis (tropical clawed frog)	casp6	NP_001011068.1
Homo sapiens (human)	CASP6	NP_001217.2
Pan troglodytes (chimpanzee)	CASP6	XP_001136602.2
	LOC698788	XP_002804209.1
Danio rerio (zebrafish)	casp6	NP_001018333.1
Canis lupus familiaris (dog)	CASP6	XP_545022.3
Rattus norvegicus (Norway rat)	Casp6	NP_001258913.1

Gene Ontology
Bibliography

Related articles in PubMed

Caspase-6 is a Dispensable Enabler of Adult Mammalian Axonal Degeneration.
Woo V, Cheng C, Duraikannu A, Chandrasekhar A, Purdy K, Martinez JA, Zochodne DW
Neuroscience371242-253(2017 Dec)

Selenium Plays a Protective Role in Staphylococcus aureus-Induced Endometritis in the Uterine Tissue of Rats.
Liu Y, Qiu C, Li W, Mu W, Li C, Guo M
Biological trace element research173(2)345-53(2016 Oct)

4'-O-?-D-Glucosyl-5-O-Methylvisamminol, A Natural Histone H3 Phosphorylation Epigenetic Suppressor, Exerts a Neuroprotective Effect Through PI3K/Akt Signaling Pathway on Focal Cerebral Ischemia in Rats.
Chang CZ, Wu SC
World neurosurgery89474-88(2016 May)

Death Receptor 6 and Caspase-6 Regulate Prion Peptide-Induced Axonal Degeneration in Rat Spinal Neurons.
Wang Y, Zhao D, Pan B, Song Z, Shah SZA, Yin X, Zhou X, Yang L
Journal of molecular neuroscience : MN56(4)966-976(2015 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Caspase-6 shows a time-dependent expression in PMNs, MNCs and FBCs during skin injury repair in rat.
Title: [A study on the time-dependent expression of caspase-6 during repair of skin contusion in rats].

Testosterone inhibits apoptosis in the ventral prostate by potentially targeting the transcriptional activity of effector caspase-6 genes (but not of casapase-8 gene) as well as the cleavage of procaspase-6 into active enzymes.
Title: Caspase-3 and -6 expression and activation are targeted by hormone action in the rat ventral prostate during the apoptotic cell death process.

nuclear fragmentation in rat blastocysts is apparently mediated by the activation of caspase-6
Title: Identification of caspase-6 in rat blastocysts and its implication in the induction of apoptosis by high glucose.

Neuronal caspase-6 immunoreactivity was markedly upregulated within cortex and hippocampus in relation to bursts of polyspike paroxysmal discharges.
Title: Expression and differential processing of caspases 6 and 7 in relation to specific epileptiform EEG patterns following limbic seizures.

Cyclophilin-A is involved in excitotoxin-induced caspase activation in rat neuronal B50 cells
Title: Cyclophilin-A is involved in excitotoxin-induced caspase activation in rat neuronal B50 cells.

The following Casp6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Casp6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa08703	NM_031775.3 Latest version!	Rattus norvegicus caspase 6 (Casp6), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
ORa08703	NM_001271984.1 Latest version!	Rattus norvegicus caspase 6 (Casp6), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
ORa25243	XM_017591135.1 Latest version!	Rattus norvegicus caspase 6 (Casp6), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
ORa25243	XM_008761528.2 Latest version!	Rattus norvegicus caspase 6 (Casp6), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Casp6 ( NM_001271984.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001258913.1 Rattus norvegicus caspase 6 (Casp6), transcript variant 2, mRNA.

Price & Availability↑

CloneID	ORa08703
Clone ID Related Accession (Same CDS sequence)	NM_001271984.1 , NM_031775.3
Accession Version	NM_001271984.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 834bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-15
Organism	Rattus norvegicus(Norway rat)
Product	caspase-6
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from FM068086.1, DY310578.1 and BC078785.1. Transcript Variant: This variant (2) lacks an exon in the 5' UTR, compared to variant 1. Variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: DY310578.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMEA2689594 [ECO:0000348] ##Evidence-Data-END##

ATGACGGAGA CAGATGGCTT CTACAGAAGT AGGGAAGTGT TGGATCCAGC CGAGCAGTAC 
AAGATGGACC ACAAGAGGAG AGGAACTGCC CTAATCTTCA ATCACGAGAG GTTCTTCTGG 
CACCTAGCAC TCCCAGAGAG GCGGGGCACC AACGCAGACA GGGACAACCT GACTCGAAGG 
TTCTCAGAGC TAGGATTTGA AGTGAAATGC TTTAACGACC TCCGGGCAGA AGAACTACTG 
CTCAAGATTC ACGAGGTGTC GACTTCCAGC CACGTAGATG CCGATTGCTT CCTGTGTGTC 
TTCCTGAGCC ACGGGGAAGG CAACCACATT TACGCATACG ATGCCAAAAT TGAAATTCAG 
ACCTTGACTG GCTTGTTCAA AGGAGACAAG TGTCAGAGCC TGGTTGGAAA ACCCAAGATA 
TTCATCATCC AGGCCTGTCG GGGCAGCCAG CATGACGTGC CCGTGGTTCC TCTGGACGTG 
GTGGATCATC AGACAGACAA GCTGGACGAC AACGTGACCC AGGTGGATGC TGCCTCGGTG 
TACACTCTGC CTGCGGGGGC GGACTTCCTC ATGTGTTACT CTGTTGCAGA AGGGTATTAC 
TCTCACCGAG AGACTGTGAA CGGCTCCTGG TACATTCAGG ATTTGTGCGA GATGCTGGCC 
AGGCACGGTA GTTCCCTGGA GTTCACCGAG CTGCTCACGC TGGTGAACAG GAAGGTCTCT 
CAGCGCCGTG TGGATTTCTG CAAAGACCCA GGTGCAATTG GCAAGAAGCA GGTTCCCTGC 
TTTGCCTCAA TGCTGACCAA AAAGCTGCAT TTCTGTCCCA AACCTAGTAA GTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001258913.1
CDS	67..900
Translation	MTETDGFYRSREVLDPAEQYKMDHKRRGTALIFNHERFFWHLALPERRGTNADRDNLTRRFSELGFEVKCFNDLRAEELLLKIHEVSTSSHVDADCFLCVFLSHGEGNHIYAYDAKIEIQTLTGLFKGDKCQSLVGKPKIFIIQACRGSQHDVPVVPLDVVDHQTDKLDDNVTQVDAASVYTLPAGADFLMCYSVAEGYYSHRETVNGSWYIQDLCEMLARHGSSLEFTELLTLVNRKVSQRRVDFCKDPGAIGKKQVPCFASMLTKKLHFCPKPSK

Target ORF information:

RefSeq Version	NM_001271984.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus caspase 6 (Casp6), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001271984.1

ORF Insert Sequence:

ATGACGGAGA CAGATGGCTT CTACAGAAGT AGGGAAGTGT TGGATCCAGC CGAGCAGTAC 
AAGATGGACC ACAAGAGGAG AGGAACTGCC CTAATCTTCA ATCACGAGAG GTTCTTCTGG 
CACCTAGCAC TCCCAGAGAG GCGGGGCACC AACGCAGACA GGGACAACCT GACTCGAAGG 
TTCTCAGAGC TAGGATTTGA AGTGAAATGC TTTAACGACC TCCGGGCAGA AGAACTACTG 
CTCAAGATTC ACGAGGTGTC GACTTCCAGC CACGTAGATG CCGATTGCTT CCTGTGTGTC 
TTCCTGAGCC ACGGGGAAGG CAACCACATT TACGCATACG ATGCCAAAAT TGAAATTCAG 
ACCTTGACTG GCTTGTTCAA AGGAGACAAG TGTCAGAGCC TGGTTGGAAA ACCCAAGATA 
TTCATCATCC AGGCCTGTCG GGGCAGCCAG CATGACGTGC CCGTGGTTCC TCTGGACGTG 
GTGGATCATC AGACAGACAA GCTGGACGAC AACGTGACCC AGGTGGATGC TGCCTCGGTG 
TACACTCTGC CTGCGGGGGC GGACTTCCTC ATGTGTTACT CTGTTGCAGA AGGGTATTAC 
TCTCACCGAG AGACTGTGAA CGGCTCCTGG TACATTCAGG ATTTGTGCGA GATGCTGGCC 
AGGCACGGTA GTTCCCTGGA GTTCACCGAG CTGCTCACGC TGGTGAACAG GAAGGTCTCT 
CAGCGCCGTG TGGATTTCTG CAAAGACCCA GGTGCAATTG GCAAGAAGCA GGTTCCCTGC 
TTTGCCTCAA TGCTGACCAA AAAGCTGCAT TTCTGTCCCA AACCTAGTAA GTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Casp6 ( NM_031775.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_113963.2 Rattus norvegicus caspase 6 (Casp6), transcript variant 1, mRNA.

Price & Availability↑

CloneID	ORa08703
Clone ID Related Accession (Same CDS sequence)	NM_001271984.1 , NM_031775.3
Accession Version	NM_031775.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 834bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-16
Organism	Rattus norvegicus(Norway rat)
Product	caspase-6
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from FM068086.1 and BC078785.1. On Dec 19, 2012 this sequence version replaced NM_031775.2. Transcript Variant: This variant (1) is the longer transcript. Variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC078785.1, AF025670.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2689594, SAMEA2689597 [ECO:0000348] ##Evidence-Data-END##

ATGACGGAGA CAGATGGCTT CTACAGAAGT AGGGAAGTGT TGGATCCAGC CGAGCAGTAC 
AAGATGGACC ACAAGAGGAG AGGAACTGCC CTAATCTTCA ATCACGAGAG GTTCTTCTGG 
CACCTAGCAC TCCCAGAGAG GCGGGGCACC AACGCAGACA GGGACAACCT GACTCGAAGG 
TTCTCAGAGC TAGGATTTGA AGTGAAATGC TTTAACGACC TCCGGGCAGA AGAACTACTG 
CTCAAGATTC ACGAGGTGTC GACTTCCAGC CACGTAGATG CCGATTGCTT CCTGTGTGTC 
TTCCTGAGCC ACGGGGAAGG CAACCACATT TACGCATACG ATGCCAAAAT TGAAATTCAG 
ACCTTGACTG GCTTGTTCAA AGGAGACAAG TGTCAGAGCC TGGTTGGAAA ACCCAAGATA 
TTCATCATCC AGGCCTGTCG GGGCAGCCAG CATGACGTGC CCGTGGTTCC TCTGGACGTG 
GTGGATCATC AGACAGACAA GCTGGACGAC AACGTGACCC AGGTGGATGC TGCCTCGGTG 
TACACTCTGC CTGCGGGGGC GGACTTCCTC ATGTGTTACT CTGTTGCAGA AGGGTATTAC 
TCTCACCGAG AGACTGTGAA CGGCTCCTGG TACATTCAGG ATTTGTGCGA GATGCTGGCC 
AGGCACGGTA GTTCCCTGGA GTTCACCGAG CTGCTCACGC TGGTGAACAG GAAGGTCTCT 
CAGCGCCGTG TGGATTTCTG CAAAGACCCA GGTGCAATTG GCAAGAAGCA GGTTCCCTGC 
TTTGCCTCAA TGCTGACCAA AAAGCTGCAT TTCTGTCCCA AACCTAGTAA GTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_113963.2
CDS	222..1055
Translation	MTETDGFYRSREVLDPAEQYKMDHKRRGTALIFNHERFFWHLALPERRGTNADRDNLTRRFSELGFEVKCFNDLRAEELLLKIHEVSTSSHVDADCFLCVFLSHGEGNHIYAYDAKIEIQTLTGLFKGDKCQSLVGKPKIFIIQACRGSQHDVPVVPLDVVDHQTDKLDDNVTQVDAASVYTLPAGADFLMCYSVAEGYYSHRETVNGSWYIQDLCEMLARHGSSLEFTELLTLVNRKVSQRRVDFCKDPGAIGKKQVPCFASMLTKKLHFCPKPSK

Target ORF information:

RefSeq Version	NM_031775.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus caspase 6 (Casp6), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_031775.3

ORF Insert Sequence:

ATGACGGAGA CAGATGGCTT CTACAGAAGT AGGGAAGTGT TGGATCCAGC CGAGCAGTAC 
AAGATGGACC ACAAGAGGAG AGGAACTGCC CTAATCTTCA ATCACGAGAG GTTCTTCTGG 
CACCTAGCAC TCCCAGAGAG GCGGGGCACC AACGCAGACA GGGACAACCT GACTCGAAGG 
TTCTCAGAGC TAGGATTTGA AGTGAAATGC TTTAACGACC TCCGGGCAGA AGAACTACTG 
CTCAAGATTC ACGAGGTGTC GACTTCCAGC CACGTAGATG CCGATTGCTT CCTGTGTGTC 
TTCCTGAGCC ACGGGGAAGG CAACCACATT TACGCATACG ATGCCAAAAT TGAAATTCAG 
ACCTTGACTG GCTTGTTCAA AGGAGACAAG TGTCAGAGCC TGGTTGGAAA ACCCAAGATA 
TTCATCATCC AGGCCTGTCG GGGCAGCCAG CATGACGTGC CCGTGGTTCC TCTGGACGTG 
GTGGATCATC AGACAGACAA GCTGGACGAC AACGTGACCC AGGTGGATGC TGCCTCGGTG 
TACACTCTGC CTGCGGGGGC GGACTTCCTC ATGTGTTACT CTGTTGCAGA AGGGTATTAC 
TCTCACCGAG AGACTGTGAA CGGCTCCTGG TACATTCAGG ATTTGTGCGA GATGCTGGCC 
AGGCACGGTA GTTCCCTGGA GTTCACCGAG CTGCTCACGC TGGTGAACAG GAAGGTCTCT 
CAGCGCCGTG TGGATTTCTG CAAAGACCCA GGTGCAATTG GCAAGAAGCA GGTTCCCTGC 
TTTGCCTCAA TGCTGACCAA AAAGCTGCAT TTCTGTCCCA AACCTAGTAA GTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Casp6 ( XM_017591135.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017446624.1 Rattus norvegicus caspase 6 (Casp6), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa25243
Clone ID Related Accession (Same CDS sequence)	XM_017591135.1 , XM_008761528.2
Accession Version	XM_017591135.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 831bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	caspase-6 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005101.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACGGAGA CAGATGGCTT CTACAGAAGG GAAGTGTTGG ATCCAGCCGA GCAGTACAAG 
ATGGACCACA AGAGGAGAGG AACTGCCCTA ATCTTCAATC ACGAGAGGTT CTTCTGGCAC 
CTAGCACTCC CAGAGAGGCG GGGCACCAAC GCAGACAGGG ACAACCTGAC TCGAAGGTTC 
TCAGAGCTAG GATTTGAAGT GAAATGCTTT AACGACCTCC GGGCAGAAGA ACTACTGCTC 
AAGATTCACG AGGTGTCGAC TTCCAGCCAC GTAGATGCCG ATTGCTTCCT GTGTGTCTTC 
CTGAGCCACG GGGAAGGCAA CCACATTTAC GCATACGATG CCAAAATTGA AATTCAGACC 
TTGACTGGCT TGTTCAAAGG AGACAAGTGT CAGAGCCTGG TTGGAAAACC CAAGATATTC 
ATCATCCAGG CCTGTCGGGG CAGCCAGCAT GACGTGCCCG TGGTTCCTCT GGACGTGGTG 
GATCATCAGA CAGACAAGCT GGACGACAAC GTGACCCAGG TGGATGCTGC CTCGGTGTAC 
ACTCTGCCTG CGGGGGCGGA CTTCCTCATG TGTTACTCTG TTGCAGAAGG GTATTACTCT 
CACCGAGAGA CTGTGAACGG CTCCTGGTAC ATTCAGGATT TGTGCGAGAT GCTGGCCAGG 
CACGGTAGTT CCCTGGAGTT CACCGAGCTG CTCACGCTGG TGAACAGGAA GGTCTCTCAG 
CGCCGTGTGG ATTTCTGCAA AGACCCAGGT GCAATTGGCA AGAAGCAGGT TCCCTGCTTT 
GCCTCAATGC TGACCAAAAA GCTGCATTTC TGTCCCAAAC CTAGTAAGTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017446624.1
CDS	266..1096
Translation	MTETDGFYRREVLDPAEQYKMDHKRRGTALIFNHERFFWHLALPERRGTNADRDNLTRRFSELGFEVKCFNDLRAEELLLKIHEVSTSSHVDADCFLCVFLSHGEGNHIYAYDAKIEIQTLTGLFKGDKCQSLVGKPKIFIIQACRGSQHDVPVVPLDVVDHQTDKLDDNVTQVDAASVYTLPAGADFLMCYSVAEGYYSHRETVNGSWYIQDLCEMLARHGSSLEFTELLTLVNRKVSQRRVDFCKDPGAIGKKQVPCFASMLTKKLHFCPKPSK

Target ORF information:

RefSeq Version	XM_017591135.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus caspase 6 (Casp6), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017591135.1

ORF Insert Sequence:

ATGACGGAGA CAGATGGCTT CTACAGAAGG GAAGTGTTGG ATCCAGCCGA GCAGTACAAG 
ATGGACCACA AGAGGAGAGG AACTGCCCTA ATCTTCAATC ACGAGAGGTT CTTCTGGCAC 
CTAGCACTCC CAGAGAGGCG GGGCACCAAC GCAGACAGGG ACAACCTGAC TCGAAGGTTC 
TCAGAGCTAG GATTTGAAGT GAAATGCTTT AACGACCTCC GGGCAGAAGA ACTACTGCTC 
AAGATTCACG AGGTGTCGAC TTCCAGCCAC GTAGATGCCG ATTGCTTCCT GTGTGTCTTC 
CTGAGCCACG GGGAAGGCAA CCACATTTAC GCATACGATG CCAAAATTGA AATTCAGACC 
TTGACTGGCT TGTTCAAAGG AGACAAGTGT CAGAGCCTGG TTGGAAAACC CAAGATATTC 
ATCATCCAGG CCTGTCGGGG CAGCCAGCAT GACGTGCCCG TGGTTCCTCT GGACGTGGTG 
GATCATCAGA CAGACAAGCT GGACGACAAC GTGACCCAGG TGGATGCTGC CTCGGTGTAC 
ACTCTGCCTG CGGGGGCGGA CTTCCTCATG TGTTACTCTG TTGCAGAAGG GTATTACTCT 
CACCGAGAGA CTGTGAACGG CTCCTGGTAC ATTCAGGATT TGTGCGAGAT GCTGGCCAGG 
CACGGTAGTT CCCTGGAGTT CACCGAGCTG CTCACGCTGG TGAACAGGAA GGTCTCTCAG 
CGCCGTGTGG ATTTCTGCAA AGACCCAGGT GCAATTGGCA AGAAGCAGGT TCCCTGCTTT 
GCCTCAATGC TGACCAAAAA GCTGCATTTC TGTCCCAAAC CTAGTAAGTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Casp6 ( XM_008761528.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008759750.1 Rattus norvegicus caspase 6 (Casp6), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa25243
Clone ID Related Accession (Same CDS sequence)	XM_017591135.1 , XM_008761528.2
Accession Version	XM_008761528.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 831bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	caspase-6 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005101.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008761528.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACGGAGA CAGATGGCTT CTACAGAAGG GAAGTGTTGG ATCCAGCCGA GCAGTACAAG 
ATGGACCACA AGAGGAGAGG AACTGCCCTA ATCTTCAATC ACGAGAGGTT CTTCTGGCAC 
CTAGCACTCC CAGAGAGGCG GGGCACCAAC GCAGACAGGG ACAACCTGAC TCGAAGGTTC 
TCAGAGCTAG GATTTGAAGT GAAATGCTTT AACGACCTCC GGGCAGAAGA ACTACTGCTC 
AAGATTCACG AGGTGTCGAC TTCCAGCCAC GTAGATGCCG ATTGCTTCCT GTGTGTCTTC 
CTGAGCCACG GGGAAGGCAA CCACATTTAC GCATACGATG CCAAAATTGA AATTCAGACC 
TTGACTGGCT TGTTCAAAGG AGACAAGTGT CAGAGCCTGG TTGGAAAACC CAAGATATTC 
ATCATCCAGG CCTGTCGGGG CAGCCAGCAT GACGTGCCCG TGGTTCCTCT GGACGTGGTG 
GATCATCAGA CAGACAAGCT GGACGACAAC GTGACCCAGG TGGATGCTGC CTCGGTGTAC 
ACTCTGCCTG CGGGGGCGGA CTTCCTCATG TGTTACTCTG TTGCAGAAGG GTATTACTCT 
CACCGAGAGA CTGTGAACGG CTCCTGGTAC ATTCAGGATT TGTGCGAGAT GCTGGCCAGG 
CACGGTAGTT CCCTGGAGTT CACCGAGCTG CTCACGCTGG TGAACAGGAA GGTCTCTCAG 
CGCCGTGTGG ATTTCTGCAA AGACCCAGGT GCAATTGGCA AGAAGCAGGT TCCCTGCTTT 
GCCTCAATGC TGACCAAAAA GCTGCATTTC TGTCCCAAAC CTAGTAAGTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008759750.1
CDS	115..945
Translation	MTETDGFYRREVLDPAEQYKMDHKRRGTALIFNHERFFWHLALPERRGTNADRDNLTRRFSELGFEVKCFNDLRAEELLLKIHEVSTSSHVDADCFLCVFLSHGEGNHIYAYDAKIEIQTLTGLFKGDKCQSLVGKPKIFIIQACRGSQHDVPVVPLDVVDHQTDKLDDNVTQVDAASVYTLPAGADFLMCYSVAEGYYSHRETVNGSWYIQDLCEMLARHGSSLEFTELLTLVNRKVSQRRVDFCKDPGAIGKKQVPCFASMLTKKLHFCPKPSK

Target ORF information:

RefSeq Version	XM_008761528.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus caspase 6 (Casp6), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008761528.2

ORF Insert Sequence:

ATGACGGAGA CAGATGGCTT CTACAGAAGG GAAGTGTTGG ATCCAGCCGA GCAGTACAAG 
ATGGACCACA AGAGGAGAGG AACTGCCCTA ATCTTCAATC ACGAGAGGTT CTTCTGGCAC 
CTAGCACTCC CAGAGAGGCG GGGCACCAAC GCAGACAGGG ACAACCTGAC TCGAAGGTTC 
TCAGAGCTAG GATTTGAAGT GAAATGCTTT AACGACCTCC GGGCAGAAGA ACTACTGCTC 
AAGATTCACG AGGTGTCGAC TTCCAGCCAC GTAGATGCCG ATTGCTTCCT GTGTGTCTTC 
CTGAGCCACG GGGAAGGCAA CCACATTTAC GCATACGATG CCAAAATTGA AATTCAGACC 
TTGACTGGCT TGTTCAAAGG AGACAAGTGT CAGAGCCTGG TTGGAAAACC CAAGATATTC 
ATCATCCAGG CCTGTCGGGG CAGCCAGCAT GACGTGCCCG TGGTTCCTCT GGACGTGGTG 
GATCATCAGA CAGACAAGCT GGACGACAAC GTGACCCAGG TGGATGCTGC CTCGGTGTAC 
ACTCTGCCTG CGGGGGCGGA CTTCCTCATG TGTTACTCTG TTGCAGAAGG GTATTACTCT 
CACCGAGAGA CTGTGAACGG CTCCTGGTAC ATTCAGGATT TGTGCGAGAT GCTGGCCAGG 
CACGGTAGTT CCCTGGAGTT CACCGAGCTG CTCACGCTGG TGAACAGGAA GGTCTCTCAG 
CGCCGTGTGG ATTTCTGCAA AGACCCAGGT GCAATTGGCA AGAAGCAGGT TCCCTGCTTT 
GCCTCAATGC TGACCAAAAA GCTGCATTTC TGTCCCAAAC CTAGTAAGTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Caspase-6 is a Dispensable Enabler of Adult Mammalian Axonal Degeneration.
Neuroscience371242-253(2017 Dec)
Woo V,Cheng C,Duraikannu A,Chandrasekhar A,Purdy K,Martinez JA,Zochodne DW

Selenium Plays a Protective Role in Staphylococcus aureus-Induced Endometritis in the Uterine Tissue of Rats.
Biological trace element research173(2)345-53(2016 Oct)
Liu Y,Qiu C,Li W,Mu W,Li C,Guo M

4'-O-?-D-Glucosyl-5-O-Methylvisamminol, A Natural Histone H3 Phosphorylation Epigenetic Suppressor, Exerts a Neuroprotective Effect Through PI3K/Akt Signaling Pathway on Focal Cerebral Ischemia in Rats.
World neurosurgery89474-88(2016 May)
Chang CZ,Wu SC

Death Receptor 6 and Caspase-6 Regulate Prion Peptide-Induced Axonal Degeneration in Rat Spinal Neurons.
Journal of molecular neuroscience : MN56(4)966-976(2015 Aug)
Wang Y,Zhao D,Pan B,Song Z,Shah SZA,Yin X,Zhou X,Yang L

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Casp6 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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