Trib1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Trib1
Entrez Gene ID	78969
Full Name	tribbles pseudokinase 1
Synonyms	Gig2
General protein information	Preferred Names tribbles pseudokinase 1 Names tribbles homolog 1 G-protein-coupled receptor induced protein GIG2
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 7 Map Location: 7q33
Summary	a nuclear factor; gene expression induced by m1-acetylcholine receptor [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_023985.1	NP_076475.1	tribbles homolog 1

Pathways from BioSystems

Homologies

	TRIB1	XP_001082540.1
Mus musculus (house mouse)	Trib1	NP_653132.1
Gallus gallus (chicken)	LOC428386	XP_425946.4
Homo sapiens (human)	TRIB1	NP_079471.1
Canis lupus familiaris (dog)	TRIB1	XP_539160.2
Xenopus tropicalis (tropical clawed frog)	trib1	XP_002938707.1
Pan troglodytes (chimpanzee)	TRIB1	XP_519955.2
Rattus norvegicus (Norway rat)	Trib1	NP_076475.1
Bos taurus (cattle)	TRIB1	NP_001094575.1

Gene Ontology
Bibliography

Related articles in PubMed

Critical role of Trib1 in differentiation of tissue-resident M2-like macrophages.
Satoh T, Kidoya H, Naito H, Yamamoto M, Takemura N, Nakagawa K, Yoshioka Y, Morii E, Takakura N, Takeuchi O, Akira S
Nature495(7442)524-8(2013 Mar)

Differential ability of Tribbles family members to promote degradation of C/EBPalpha and induce acute myelogenous leukemia.
Dedhia PH, Keeshan K, Uljon S, Xu L, Vega ME, Shestova O, Zaks-Zilberman M, Romany C, Blacklow SC, Pear WS
Blood116(8)1321-8(2010 Aug)

Enhanced TLR-mediated NF-IL6 dependent gene expression by Trib1 deficiency.
Yamamoto M, Uematsu S, Okamoto T, Matsuura Y, Sato S, Kumar H, Satoh T, Saitoh T, Takeda K, Ishii KJ, Takeuchi O, Kawai T, Akira S
The Journal of experimental medicine204(9)2233-9(2007 Sep)

Human tribbles-1 controls proliferation and chemotaxis of smooth muscle cells via MAPK signaling pathways.
Sung HY, Guan H, Czibula A, King AR, Eder K, Heath E, Suvarna SK, Dower SK, Wilson AG, Francis SE, Crossman DC, Kiss-Toth E
The Journal of biological chemistry282(25)18379-87(2007 Jun)

Human tribbles, a protein family controlling mitogen-activated protein kinase cascades.
Kiss-Toth E, Bagstaff SM, Sung HY, Jozsa V, Dempsey C, Caunt JC, Oxley KM, Wyllie DH, Polgar T, Harte M, O'neill LA, Qwarnstrom EE, Dower SK
The Journal of biological chemistry279(41)42703-8(2004 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Trib1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Trib1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa06719	NM_023985.1 Latest version!	Rattus norvegicus tribbles pseudokinase 1 (Trib1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Trib1 ( NM_023985.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_076475.1 Rattus norvegicus tribbles pseudokinase 1 (Trib1), mRNA.

Price & Availability↑

CloneID	ORa06719
Clone ID Related Accession (Same CDS sequence)	NM_023985.1
Accession Version	NM_023985.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1119bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-27
Organism	Rattus norvegicus(Norway rat)
Product	tribbles homolog 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AI601976.1, AW530250.1, BE096693.1, AF205438.1 and AA964141.1. On or before Jan 20, 2007 this sequence version replaced XM_343250.3, XM_001065461.1. ##Evidence-Data-START## Transcript exon combination :: AF205438.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGCGGGTCG GTCCCGTGCG TTTTGCCCTG AGCGGCGCCT CGCAGCCCCG CGGACCGGCT 
CTACTGTTCC CGGCTGCCCG GGGCACCCCG GCCAAACGCC TGCTGGACAC GGACGACGCG 
GCGGCCGTGG CGGCCAAGTG TCCGCGCCTC TCTGAGTGCT CGAATCCCCC TGACTACCTC 
AGTCCCCCCG GCTCGCCCTG CAGTCCTCAG CCTCCACCCT CGGCGCAGGG GACCGGCGGC 
AGCTGTGTGA GCGCACCCGG GCCCAGCCGA ATCGCCGACT ACCTGCTGCT ACCCCTAGCT 
GAGCGCGAGC ATGTGTCCCG GGCACTGTGC ATCCACACCG GCCGCGAGCT GCGCTGCAAG 
GTGTTTCCCA TTAAACACTA CCAAGACAAA ATCAGGCCTT ACACCCAGCT GCCGTCCCAT 
AGAAACATTA CTGGCATCGT GGAAGTGATC CTCGGGGAGA GCAAGGCCTA CGTTTTCTTT 
GAGAAGGACT TTGGAGACAT GCACTCCTAT GTACGAAGCC GGAAAAGGCT TCGGGAAGAG 
GAGGCCGCTC GGCTCTTCAA GCAAATTGTT TCCGCCGTTG CCCACTGCCA CCAGTCAGCC 
ATTGTGCTGG GGGACCTGAA GCTTAGGAAA TTCGTCTTCT CCACAGAGGA GAGGACCCAG 
CTTAGACTGG AAAGCCTAGA AGATACGCAC ATGATAAAGG GTGAAGATGA CGCATTGTCA 
GATAAACATG GCTGCCCGGC CTATGTGAGC CCTGAGATCC TCAACACTAC TGGGACCTAC 
TCCGGAAAGG CAGCGGATGT TTGGAGCCTT GGGGTGATGC TCTACACCCT TTTGGTCGGA 
CGATACCCCT TTCATGACTC AGACCCGAGC GCCCTTTTCT CCAAAATCCG TCGGGGACAG 
TTTTGCATTC CCGAGCATGT TTCCCCCAAA GCCAGGTGCC TCATCCGCAG CCTCCTGAGA 
CGAGAACCTT CTGAGAGACT CACAGCTCCT GAGATCTTAC TCCATCCCTG GTTTGAATAC 
GTCTTGGAAC CGGGGTATGT TGACTCAGAA GTAGGAACTT CTGACCAGAT TGTTCCCGAG 
TACCAGGACG ACAATGACGT TAGTTCCTTT TTCTGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_076475.1
CDS	605..1723
Translation	MRVGPVRFALSGASQPRGPALLFPAARGTPAKRLLDTDDAAAVAAKCPRLSECSNPPDYLSPPGSPCSPQPPPSAQGTGGSCVSAPGPSRIADYLLLPLAEREHVSRALCIHTGRELRCKVFPIKHYQDKIRPYTQLPSHRNITGIVEVILGESKAYVFFEKDFGDMHSYVRSRKRLREEEAARLFKQIVSAVAHCHQSAIVLGDLKLRKFVFSTEERTQLRLESLEDTHMIKGEDDALSDKHGCPAYVSPEILNTTGTYSGKAADVWSLGVMLYTLLVGRYPFHDSDPSALFSKIRRGQFCIPEHVSPKARCLIRSLLRREPSERLTAPEILLHPWFEYVLEPGYVDSEVGTSDQIVPEYQDDNDVSSFFC

Target ORF information:

RefSeq Version	NM_023985.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus tribbles pseudokinase 1 (Trib1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_023985.1

ORF Insert Sequence:

ATGCGGGTCG GTCCCGTGCG TTTTGCCCTG AGCGGCGCCT CGCAGCCCCG CGGACCGGCT 
CTACTGTTCC CGGCTGCCCG GGGCACCCCG GCCAAACGCC TGCTGGACAC GGACGACGCG 
GCGGCCGTGG CGGCCAAGTG TCCGCGCCTC TCTGAGTGCT CGAATCCCCC TGACTACCTC 
AGTCCCCCCG GCTCGCCCTG CAGTCCTCAG CCTCCACCCT CGGCGCAGGG GACCGGCGGC 
AGCTGTGTGA GCGCACCCGG GCCCAGCCGA ATCGCCGACT ACCTGCTGCT ACCCCTAGCT 
GAGCGCGAGC ATGTGTCCCG GGCACTGTGC ATCCACACCG GCCGCGAGCT GCGCTGCAAG 
GTGTTTCCCA TTAAACACTA CCAAGACAAA ATCAGGCCTT ACACCCAGCT GCCGTCCCAT 
AGAAACATTA CTGGCATCGT GGAAGTGATC CTCGGGGAGA GCAAGGCCTA CGTTTTCTTT 
GAGAAGGACT TTGGAGACAT GCACTCCTAT GTACGAAGCC GGAAAAGGCT TCGGGAAGAG 
GAGGCCGCTC GGCTCTTCAA GCAAATTGTT TCCGCCGTTG CCCACTGCCA CCAGTCAGCC 
ATTGTGCTGG GGGACCTGAA GCTTAGGAAA TTCGTCTTCT CCACAGAGGA GAGGACCCAG 
CTTAGACTGG AAAGCCTAGA AGATACGCAC ATGATAAAGG GTGAAGATGA CGCATTGTCA 
GATAAACATG GCTGCCCGGC CTATGTGAGC CCTGAGATCC TCAACACTAC TGGGACCTAC 
TCCGGAAAGG CAGCGGATGT TTGGAGCCTT GGGGTGATGC TCTACACCCT TTTGGTCGGA 
CGATACCCCT TTCATGACTC AGACCCGAGC GCCCTTTTCT CCAAAATCCG TCGGGGACAG 
TTTTGCATTC CCGAGCATGT TTCCCCCAAA GCCAGGTGCC TCATCCGCAG CCTCCTGAGA 
CGAGAACCTT CTGAGAGACT CACAGCTCCT GAGATCTTAC TCCATCCCTG GTTTGAATAC 
GTCTTGGAAC CGGGGTATGT TGACTCAGAA GTAGGAACTT CTGACCAGAT TGTTCCCGAG 
TACCAGGACG ACAATGACGT TAGTTCCTTT TTCTGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Critical role of Trib1 in differentiation of tissue-resident M2-like macrophages.
Nature495(7442)524-8(2013 Mar)
Satoh T,Kidoya H,Naito H,Yamamoto M,Takemura N,Nakagawa K,Yoshioka Y,Morii E,Takakura N,Takeuchi O,Akira S

Differential ability of Tribbles family members to promote degradation of C/EBPalpha and induce acute myelogenous leukemia.
Blood116(8)1321-8(2010 Aug)
Dedhia PH,Keeshan K,Uljon S,Xu L,Vega ME,Shestova O,Zaks-Zilberman M,Romany C,Blacklow SC,Pear WS

Enhanced TLR-mediated NF-IL6 dependent gene expression by Trib1 deficiency.
The Journal of experimental medicine204(9)2233-9(2007 Sep)
Yamamoto M,Uematsu S,Okamoto T,Matsuura Y,Sato S,Kumar H,Satoh T,Saitoh T,Takeda K,Ishii KJ,Takeuchi O,Kawai T,Akira S

Human tribbles-1 controls proliferation and chemotaxis of smooth muscle cells via MAPK signaling pathways.
The Journal of biological chemistry282(25)18379-87(2007 Jun)
Sung HY,Guan H,Czibula A,King AR,Eder K,Heath E,Suvarna SK,Dower SK,Wilson AG,Francis SE,Crossman DC,Kiss-Toth E

Human tribbles, a protein family controlling mitogen-activated protein kinase cascades.
The Journal of biological chemistry279(41)42703-8(2004 Oct)
Kiss-Toth E,Bagstaff SM,Sung HY,Jozsa V,Dempsey C,Caunt JC,Oxley KM,Wyllie DH,Polgar T,Harte M,O'neill LA,Qwarnstrom EE,Dower SK

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Trib1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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