Trib1 cDNA ORF clone, Mus musculus(house mouse)

IL-4 as a Repurposed Biological Drug for Myocardial Infarction through Augmentation of Reparative Cardiac Macrophages: Proof-of-Concept Data in Mice.
Shintani Y, Ito T, Fields L, Shiraishi M, Ichihara Y, Sato N, Podaru M, Kainuma S, Tanaka H, Suzuki K
Scientific reports7(1)6877(2017 Jul)

The Liver Clock Controls Cholesterol Homeostasis through Trib1 Protein-mediated Regulation of PCSK9/Low Density Lipoprotein Receptor (LDLR) Axis.
Title: The Liver Clock Controls Cholesterol Homeostasis through Trib1 Protein-mediated Regulation of PCSK9/Low Density Lipoprotein Receptor (LDLR) Axis.

Deletion of hepatic Trib1 leads to increased C/EBPalpha binding near upregulated lipogenic genes, as well as Trib1 itself.
Title: Tribbles-1 regulates hepatic lipogenesis through posttranscriptional regulation of C/EBP?.

These data suggested that the modulation of TRIB1 expression affects hepatic lipogenesis and glycogenesis through multiple molecular interactions.
Title: TRIB1 downregulates hepatic lipogenesis and glycogenesis via multiple molecular interactions.

TRIB1 and TRIB3 are more strongly expressed than TRIB2 in cumulus cells (CC) surrounding oocytes from preovulatory follicles than in CC of immature ones.
Title: Tribbles expression in cumulus cells is related to oocyte maturation and fatty acid metabolism.

These results indicate that COP1 and Trib1 act as an oncoprotein complex functioning upstream of C/EBPalpha, and its ligase activity is crucial for leukemogenesis.
Title: COP1 targets C/EBP? for degradation and induces acute myeloid leukemia via Trib1.