Aplp1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Aplp1
Entrez Gene ID	502317
Full Name	amyloid beta precursor like protein 1
Synonyms	Aplp1_retired,RGD1561211
General protein information	Preferred Names amyloid beta precursor like protein 1 Names amyloid-like protein 1 amyloid beta (A4) precursor-like protein 1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 1 Map Location: 1q21
Summary	interacts with Fe65 and Fe65L2, members of a family of proteins that bind beta-amyloid precursor protein [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_001100802.1	NP_001094272.1	amyloid-like protein 1 precursor
XM_008759179.1	XP_008757401.1	amyloid-like protein 1 isoform X1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	APLP1	XP_003316371.1
Xenopus tropicalis (tropical clawed frog)	aplp1	NP_001120906.1
Canis lupus familiaris (dog)	APLP1	XP_533688.4
Danio rerio (zebrafish)	aplp1	XP_001342921.4
Homo sapiens (human)	APLP1	NP_005157.1
Bos taurus (cattle)	APLP1	NP_001033184.1
Mus musculus (house mouse)	Aplp1	NP_031493.2
	APLP1	XP_001099423.1
Rattus norvegicus (Norway rat)	Aplp1	NP_001094272.1

Gene Ontology
Bibliography

Related articles in PubMed

Crystal structure of amyloid precursor-like protein 1 and heparin complex suggests a dual role of heparin in E2 dimerization.
Xue Y, Lee S, Ha Y
Proceedings of the National Academy of Sciences of the United States of America108(39)16229-34(2011 Sep)

Interaction of the amyloid precursor like protein 1 with the alpha2A-adrenergic receptor increases agonist-mediated inhibition of adenylate cyclase.
Weber B, Schaper C, Scholz J, Bein B, Rodde C, H Tonner P
Cellular signalling18(10)1748-57(2006 Oct)

Amyloid precursor proteins anchor CPEB to membranes and promote polyadenylation-induced translation.
Cao Q, Huang YS, Kan MC, Richter JD
Molecular and cellular biology25(24)10930-9(2005 Dec)

Homo- and heterodimerization of APP family members promotes intercellular adhesion.
Soba P, Eggert S, Wagner K, Zentgraf H, Siehl K, Kreger S, L?wer A, Langer A, Merdes G, Paro R, Masters CL, M?ller U, Kins S, Beyreuther K
The EMBO journal24(20)3624-34(2005 Oct)

Cortical dysplasia resembling human type 2 lissencephaly in mice lacking all three APP family members.
Herms J, Anliker B, Heber S, Ring S, Fuhrmann M, Kretzschmar H, Sisodia S, M?ller U
The EMBO journal23(20)4106-15(2004 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Aplp1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Aplp1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa09644	NM_001100802.1 Latest version!	Rattus norvegicus amyloid beta precursor like protein 1 (Aplp1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$307.30 $439.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Aplp1 ( NM_001100802.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001094272.1 Rattus norvegicus amyloid beta precursor like protein 1 (Aplp1), mRNA.

Price & Availability↑

CloneID	ORa09644
Clone ID Related Accession (Same CDS sequence)	NM_001100802.1
Accession Version	NM_001100802.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1935bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-07
Organism	Rattus norvegicus(Norway rat)
Product	amyloid-like protein 1 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC161904.1. On or before Sep 6, 2008 this sequence version replaced XM_577781.2, XM_001076030.1, XM_001075993.1, XM_001076010.1. ##Evidence-Data-START## Transcript exon combination :: BC161904.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296 [ECO:0000348] ##Evidence-Data-END##

ATGGGGCCCT CCAGCCCCAC CACTCGCGGT CAGGGTCGCC GCCGGGGCCC GCCGCCGCTG 
CCGCTGTTGC TACCACTGTC GCTGCTGCTT CTGCGCGCGC AGCTCGCCGT CGGGAACCTG 
GCTGGTGGGA GCCCCAGCGC GGCCGAGGCT CCGGGGTCGG CTCAAGTGGC TGGACTATGT 
GGGCGTCTCA CCCTTCACCG AGACCTGCGC ACCGGCCGCT GGGAACCAGA CCCACAGCGA 
TCACGACGCT GTCTTCTGGA CCCGCAGCGC GTGCTGGAGT ACTGCAGACA GATGTACCCA 
GAGCTGCACA TAGCTCGTGT GGAGCAGGCT GCACAGGCCA TCCCGATGGA GCGCTGGTGT 
GGGGGTACCC GAAGTGGCAG ATGTGCCCAC CCCCACCATG AGGTTGTGCC CTTCCATTGC 
CTGCCTGGCG AATTCGTGAG TGAAGCCCTG CTGGTGCCCG AAGGCTGTAG GTTCTTGCAC 
CAGGAGCGAA TGGACCAATG TGAGAGTTCA ACCAGGAGGC ACCAGGAGGC TCAAGAGGCC 
TGCAGCTCCC AGGGCCTCAT CCTGCACGGT TCTGGTATGC TTTTGCCCTG TGGCTCTGAT 
CGGTTCCGAG GTGTGGAGTA TGTATGCTGT CCACCTCCCG CAACTCCCAA CCCATCTGGG 
ATGGCAGTTG GTGACCCCTC TACCCGGTCC TGGCCCCTGG GGGGCAGAGC AGAGGGAGGT 
GAGGATGAAG AGGAGGTGGA ATCCTTCCCT CAGCCAGTAG ACGATTACTT CGTAGAGCCC 
CCTCAGGCCG AAGAAGAAGA GGAAGAAGAG GAGGAAAGGG CCCCACCTCC CAGCTCCCAC 
ACCCCTGTCA TGGTCAGCAG AGTCACTCCC ACCCCGAGAC CCACTGATGG TGTGGATGTT 
TACTTTGGCA TGCCTGGGGA GATCAGCGAG CACGAGGGTT TCCTGAGGGC CAAGATGGAC 
CTGGAGGAAC GTAGGATGCG TCAGATTAAT GAGGTGATGC GTGAGTGGGC CATGGCTGAC 
AGCCAATCTA AGAACCTGCC AAAAGCCGAC AGGCAGGCCC TGAATGAGCA CTTCCAGTCC 
ATTCTGCAGA CCCTGGAAGA ACAAGTGTCT GGTGAGCGAC AGCGCCTGGT GGAGACCCAC 
GCCACCAGAG TCATCGCTCT GATCAACGAC CAGCGCCGAG CTGCCCTGGA AGGTTTCCTG 
GCAGCATTAC AGGGCGATCC GCCTCAGGCT GAGAGAGTTC TGATGGCCCT GAGGCGCTAC 
CTGCGAGCGG AGCAGAAGGA GCAGAGGCAC ACCCTGAGGC ACTACCAGCA CGTGGCCGCC 
GTGGACCCTG AGAAGGCCCA GCAGATGCGC TTTCAGGTCC AGACCCACCT TCAGGTGGTT 
CAAGAACGAA TGAATCAGAG CCTGGGGCTG CTCGACCAGA ACCCTCACCT GGCTCAGGAG 
CTGCGGCCAC AGATCCAGGA GCTTCTCCAT GCGGAACACT TGGGACCTAG TGAACTGGAA 
GCCTCTGTGC CCGGGAGCAG CAGTGAGGAC AAAGATGCCC CAGTGACCCT TCCAAAAGGG 
TCCACAGATC AAGAGTCTTC CTCCTCTGGG AGAGAGAAGC TAACCCCACT GGAGCAATAT 
GAGCAAAAGG TGAATGCATC TGCCCCAAGG GGGTTTCCCT TCCACTCATC AGATATTCAG 
CGGGATGAAC TGGCACCAGC TGGGACTGGA GTGTCCCGAG AGGCCTTGTC AGGTCTGCTG 
ATCATGGGAG CTGGAGGAGG CTCCCTCATT GTCCTATCCT TGCTGCTTCT GCGCAAGAAG 
AAACCCTATG GCACTATCAG CCATGGAGTG GTGGAGGTGG ACCCCATGCT GACCCTGGAG 
GAGCAGCAGC TCCGGGAACT TCAGAGGCAT GGCTATGAGA ACCCCACCTA CCGCTTCCTG 
GAAGAACGAC CTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001094272.1
CDS	51..1985
Translation	MGPSSPTTRGQGRRRGPPPLPLLLPLSLLLLRAQLAVGNLAGGSPSAAEAPGSAQVAGLCGRLTLHRDLRTGRWEPDPQRSRRCLLDPQRVLEYCRQMYPELHIARVEQAAQAIPMERWCGGTRSGRCAHPHHEVVPFHCLPGEFVSEALLVPEGCRFLHQERMDQCESSTRRHQEAQEACSSQGLILHGSGMLLPCGSDRFRGVEYVCCPPPATPNPSGMAVGDPSTRSWPLGGRAEGGEDEEEVESFPQPVDDYFVEPPQAEEEEEEEEERAPPPSSHTPVMVSRVTPTPRPTDGVDVYFGMPGEISEHEGFLRAKMDLEERRMRQINEVMREWAMADSQSKNLPKADRQALNEHFQSILQTLEEQVSGERQRLVETHATRVIALINDQRRAALEGFLAALQGDPPQAERVLMALRRYLRAEQKEQRHTLRHYQHVAAVDPEKAQQMRFQVQTHLQVVQERMNQSLGLLDQNPHLAQELRPQIQELLHAEHLGPSELEASVPGSSSEDKDAPVTLPKGSTDQESSSSGREKLTPLEQYEQKVNASAPRGFPFHSSDIQRDELAPAGTGVSREALSGLLIMGAGGGSLIVLSLLLLRKKKPYGTISHGVVEVDPMLTLEEQQLRELQRHGYENPTYRFLEERP

Target ORF information:

RefSeq Version	NM_001100802.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus amyloid beta precursor like protein 1 (Aplp1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001100802.1

ORF Insert Sequence:

ATGGGGCCCT CCAGCCCCAC CACTCGCGGT CAGGGTCGCC GCCGGGGCCC GCCGCCGCTG 
CCGCTGTTGC TACCACTGTC GCTGCTGCTT CTGCGCGCGC AGCTCGCCGT CGGGAACCTG 
GCTGGTGGGA GCCCCAGCGC GGCCGAGGCT CCGGGGTCGG CTCAAGTGGC TGGACTATGT 
GGGCGTCTCA CCCTTCACCG AGACCTGCGC ACCGGCCGCT GGGAACCAGA CCCACAGCGA 
TCACGACGCT GTCTTCTGGA CCCGCAGCGC GTGCTGGAGT ACTGCAGACA GATGTACCCA 
GAGCTGCACA TAGCTCGTGT GGAGCAGGCT GCACAGGCCA TCCCGATGGA GCGCTGGTGT 
GGGGGTACCC GAAGTGGCAG ATGTGCCCAC CCCCACCATG AGGTTGTGCC CTTCCATTGC 
CTGCCTGGCG AATTCGTGAG TGAAGCCCTG CTGGTGCCCG AAGGCTGTAG GTTCTTGCAC 
CAGGAGCGAA TGGACCAATG TGAGAGTTCA ACCAGGAGGC ACCAGGAGGC TCAAGAGGCC 
TGCAGCTCCC AGGGCCTCAT CCTGCACGGT TCTGGTATGC TTTTGCCCTG TGGCTCTGAT 
CGGTTCCGAG GTGTGGAGTA TGTATGCTGT CCACCTCCCG CAACTCCCAA CCCATCTGGG 
ATGGCAGTTG GTGACCCCTC TACCCGGTCC TGGCCCCTGG GGGGCAGAGC AGAGGGAGGT 
GAGGATGAAG AGGAGGTGGA ATCCTTCCCT CAGCCAGTAG ACGATTACTT CGTAGAGCCC 
CCTCAGGCCG AAGAAGAAGA GGAAGAAGAG GAGGAAAGGG CCCCACCTCC CAGCTCCCAC 
ACCCCTGTCA TGGTCAGCAG AGTCACTCCC ACCCCGAGAC CCACTGATGG TGTGGATGTT 
TACTTTGGCA TGCCTGGGGA GATCAGCGAG CACGAGGGTT TCCTGAGGGC CAAGATGGAC 
CTGGAGGAAC GTAGGATGCG TCAGATTAAT GAGGTGATGC GTGAGTGGGC CATGGCTGAC 
AGCCAATCTA AGAACCTGCC AAAAGCCGAC AGGCAGGCCC TGAATGAGCA CTTCCAGTCC 
ATTCTGCAGA CCCTGGAAGA ACAAGTGTCT GGTGAGCGAC AGCGCCTGGT GGAGACCCAC 
GCCACCAGAG TCATCGCTCT GATCAACGAC CAGCGCCGAG CTGCCCTGGA AGGTTTCCTG 
GCAGCATTAC AGGGCGATCC GCCTCAGGCT GAGAGAGTTC TGATGGCCCT GAGGCGCTAC 
CTGCGAGCGG AGCAGAAGGA GCAGAGGCAC ACCCTGAGGC ACTACCAGCA CGTGGCCGCC 
GTGGACCCTG AGAAGGCCCA GCAGATGCGC TTTCAGGTCC AGACCCACCT TCAGGTGGTT 
CAAGAACGAA TGAATCAGAG CCTGGGGCTG CTCGACCAGA ACCCTCACCT GGCTCAGGAG 
CTGCGGCCAC AGATCCAGGA GCTTCTCCAT GCGGAACACT TGGGACCTAG TGAACTGGAA 
GCCTCTGTGC CCGGGAGCAG CAGTGAGGAC AAAGATGCCC CAGTGACCCT TCCAAAAGGG 
TCCACAGATC AAGAGTCTTC CTCCTCTGGG AGAGAGAAGC TAACCCCACT GGAGCAATAT 
GAGCAAAAGG TGAATGCATC TGCCCCAAGG GGGTTTCCCT TCCACTCATC AGATATTCAG 
CGGGATGAAC TGGCACCAGC TGGGACTGGA GTGTCCCGAG AGGCCTTGTC AGGTCTGCTG 
ATCATGGGAG CTGGAGGAGG CTCCCTCATT GTCCTATCCT TGCTGCTTCT GCGCAAGAAG 
AAACCCTATG GCACTATCAG CCATGGAGTG GTGGAGGTGG ACCCCATGCT GACCCTGGAG 
GAGCAGCAGC TCCGGGAACT TCAGAGGCAT GGCTATGAGA ACCCCACCTA CCGCTTCCTG 
GAAGAACGAC CTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Crystal structure of amyloid precursor-like protein 1 and heparin complex suggests a dual role of heparin in E2 dimerization.
Proceedings of the National Academy of Sciences of the United States of America108(39)16229-34(2011 Sep)
Xue Y,Lee S,Ha Y

Interaction of the amyloid precursor like protein 1 with the alpha2A-adrenergic receptor increases agonist-mediated inhibition of adenylate cyclase.
Cellular signalling18(10)1748-57(2006 Oct)
Weber B,Schaper C,Scholz J,Bein B,Rodde C,H Tonner P

Amyloid precursor proteins anchor CPEB to membranes and promote polyadenylation-induced translation.
Molecular and cellular biology25(24)10930-9(2005 Dec)
Cao Q,Huang YS,Kan MC,Richter JD

Homo- and heterodimerization of APP family members promotes intercellular adhesion.
The EMBO journal24(20)3624-34(2005 Oct)
Soba P,Eggert S,Wagner K,Zentgraf H,Siehl K,Kreger S,L?wer A,Langer A,Merdes G,Paro R,Masters CL,M?ller U,Kins S,Beyreuther K

Cortical dysplasia resembling human type 2 lissencephaly in mice lacking all three APP family members.
The EMBO journal23(20)4106-15(2004 Oct)
Herms J,Anliker B,Heber S,Ring S,Fuhrmann M,Kretzschmar H,Sisodia S,M?ller U

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Aplp1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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