Selenov cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Selenov
Entrez Gene ID	499113
Full Name	selenoprotein V
Synonyms	RGD1562943,Selv
General protein information	Preferred Names selenoprotein V Names selenoprotein V
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 1 Map Location: 1q21
Summary	This gene encodes a selenoprotein containing a selenocysteine (Sec) residue, which is encoded by the UGA codon that normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, the Sec insertion sequence (SECIS) element, which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. This protein is specifically expressed in the testis. It belongs to the SelWTH family, which possesses a thioredoxin-like fold and a conserved CxxU (C is cysteine, U is Sec) motif, suggesting a redox function for this gene. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Apr 2017].

mRNA and Protein(s)

mRNA	Protein	Name
NM_001166396.1	NP_001159868.1	selenoprotein V

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	LOC102151122	XP_005616643.1
Mus musculus (house mouse)	BC089491	NP_778198.2
Homo sapiens (human)	SELV	NP_874363.1
Pan troglodytes (chimpanzee)	SELV	NP_001140181.1
Rattus norvegicus (Norway rat)	Selv	NP_001159868.1
	SELV	XP_002801522.1

Gene Ontology
Bibliography

Related articles in PubMed

Selenoprotein Gene Nomenclature.
Gladyshev VN, Arn?r ES, Berry MJ, Brigelius-Floh? R, Bruford EA, Burk RF, Carlson BA, Castellano S, Chavatte L, Conrad M, Copeland PR, Diamond AM, Driscoll DM, Ferreiro A, Floh? L, Green FR, Guig? R, Handy DE, Hatfield DL, Hesketh J, Hoffmann PR, Holmgren A, Hondal RJ, Howard MT, Huang K, Kim HY, Kim IY, K?hrle J, Krol A, Kryukov GV, Lee BJ, Lee BC, Lei XG, Liu Q, Lescure A, Lobanov AV, Loscalzo J, Maiorino M, Mariotti M, Sandeep Prabhu K, Rayman MP, Rozovsky S, Salinas G, Schmidt EE, Schomburg L, Schweizer U, Simonovi? M, Sunde RA, Tsuji PA, Tweedie S, Ursini F, Whanger PD, Zhang Y
The Journal of biological chemistry291(46)24036-24040(2016 Nov)

[The search of partners of a new mammalian selenium-containing protein V (SelV) and expression it's mRNA during ontogenesis and spermatogenesis].
Varlamova EG, Novoselov VI
Molekuliarnaia biologiia46(2)276-84(2012 Mar-Apr)

Composition and evolution of the vertebrate and mammalian selenoproteomes.
Mariotti M, Ridge PG, Zhang Y, Lobanov AV, Pringle TH, Guigo R, Hatfield DL, Gladyshev VN
PloS one7(3)e33066(2012)

Characterization of mammalian selenoproteomes.
Kryukov GV, Castellano S, Novoselov SV, Lobanov AV, Zehtab O, Guig? R, Gladyshev VN
Science (New York, N.Y.)300(5624)1439-43(2003 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

expression of SelV mRNA in the later stages spermatogenesis, as well as in puberty and reproductive periods of rats is shown.
Title: [The search of partners of a new mammalian selenium-containing protein V (SelV) and expression it's mRNA during ontogenesis and spermatogenesis].

The following Selenov gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Selenov cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa04932	NM_001166396.1 Latest version!	Rattus norvegicus selenoprotein V (Selenov), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Selenov ( NM_001166396.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001159868.1 Rattus norvegicus selenoprotein V (Selenov), transcript variant 1, mRNA.

Price & Availability↑

CloneID	ORa04932
Clone ID Related Accession (Same CDS sequence)	NM_001166396.1
Accession Version	NM_001166396.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 981bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-27
Organism	Rattus norvegicus(Norway rat)
Product	selenoprotein V
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AABR07002795.1 and BC158767.1. On Oct 23, 2009 this sequence version replaced XR_009209.1. Transcript Variant: This variant (1) represents the predominant transcript, and encodes a selenoprotein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript and the encoded protein are supported by orthologous mouse data. ##RefSeq-Attributes-START## NMD candidate :: translation inferred from conservation protein contains selenocysteine :: inferred from conservation ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGAATAACA AGGCGCGGAA CCCCGCTCCC TCTTCAGTCC GGGCAAACAC CCCGTCCCGG 
ACACCCACTC CCGTCCGAAC CGCGACCCCA GTCAGGGCCT CGACCCCGGC GCACAACCGG 
TCTCCGGTCC GAACATCCAT CCGGGTCCGG ACTCCTGCTA ACCCTGTTCC AATTCGGTTC 
CCTACTCCAG CCCCAGCCCC TGCCCCAACT CCAACCCCAG CCCCAACTCC AGCCCCAGTC 
CCGGCCGCAG CACCGGTGCG GACTCCAGCA CCAGTCCGGG CCTCCATTCA AGGTCGGAGC 
TTTCCCACGA TCTCTCCAGT GAGATTCTTA CGGAACTTGG CCTTGCCCGC GGCACAGCCC 
CTTTCTTCCG GGGGTGCTGG CTCTCTCTCA AAGGATCTCA CGCTCGCTCA AAAGCAGAAG 
CCCTCGATCC ACAGCCTAGC GGAGGCCATC CAGGGGCCCT TTCCAGTGCT CACTCCCTCG 
GCCTCCTCGG AGACCCACGG CTCCATACCG GACCCCGCCC CTCCCACTGA CTCCTTGGCT 
TCCACTGCCA TGGCCTCCAG TACCTTGGAC CCCATTCCGG GCCCCAAACC TACACTAGAG 
TTCTTGGCCT CCCCGCTGAA GGAAACCCCT GATTTGGGTA AGCTCTCCAC AATTTCCCCA 
GCACAGAACT TCGTTTCCAC TAAGGAGGTC CCCTCCACCA GCGAGGACGT CCCAACGGCC 
AACAGAATCT TGATCCGTGT GATGTACTGT GGCCTCTGAA GCTATGGCCT TCGGTACATT 
CTACTGAAAA AGACCCTGGA GCATCAATTT CCAAACCTTC TGGAGTTTGA GGAGGAAAGA 
GCTACCCAGG TTACAGGGGA GTTTGAAGTG TTTGTGGATG GGAAATTGAT CCATTCCAAG 
AAGAAAGGCG ATGGCTTTGT GGATGAGACT AGTCTGAAGA AACTTGTGGG TGCTATTGAT 
GAAGAGATCA AGAAAAGGTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001159868.1
CDS	53..1033
Translation	MNNKARNPAPSSVRANTPSRTPTPVRTATPVRASTPAHNRSPVRTSIRVRTPANPVPIRFPTPAPAPAPTPTPAPTPAPVPAAAPVRTPAPVRASIQGRSFPTISPVRFLRNLALPAAQPLSSGGAGSLSKDLTLAQKQKPSIHSLAEAIQGPFPVLTPSASSETHGSIPDPAPPTDSLASTAMASSTLDPIPGPKPTLEFLASPLKETPDLGKLSTISPAQNFVSTKEVPSTSEDVPTANRILIRVMYCGL*SYGLRYILLKKTLEHQFPNLLEFEEERATQVTGEFEVFVDGKLIHSKKKGDGFVDETSLKKLVGAIDEEIKKR

Target ORF information:

RefSeq Version	NM_001166396.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus selenoprotein V (Selenov), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001166396.1

ORF Insert Sequence:

ATGAATAACA AGGCGCGGAA CCCCGCTCCC TCTTCAGTCC GGGCAAACAC CCCGTCCCGG 
ACACCCACTC CCGTCCGAAC CGCGACCCCA GTCAGGGCCT CGACCCCGGC GCACAACCGG 
TCTCCGGTCC GAACATCCAT CCGGGTCCGG ACTCCTGCTA ACCCTGTTCC AATTCGGTTC 
CCTACTCCAG CCCCAGCCCC TGCCCCAACT CCAACCCCAG CCCCAACTCC AGCCCCAGTC 
CCGGCCGCAG CACCGGTGCG GACTCCAGCA CCAGTCCGGG CCTCCATTCA AGGTCGGAGC 
TTTCCCACGA TCTCTCCAGT GAGATTCTTA CGGAACTTGG CCTTGCCCGC GGCACAGCCC 
CTTTCTTCCG GGGGTGCTGG CTCTCTCTCA AAGGATCTCA CGCTCGCTCA AAAGCAGAAG 
CCCTCGATCC ACAGCCTAGC GGAGGCCATC CAGGGGCCCT TTCCAGTGCT CACTCCCTCG 
GCCTCCTCGG AGACCCACGG CTCCATACCG GACCCCGCCC CTCCCACTGA CTCCTTGGCT 
TCCACTGCCA TGGCCTCCAG TACCTTGGAC CCCATTCCGG GCCCCAAACC TACACTAGAG 
TTCTTGGCCT CCCCGCTGAA GGAAACCCCT GATTTGGGTA AGCTCTCCAC AATTTCCCCA 
GCACAGAACT TCGTTTCCAC TAAGGAGGTC CCCTCCACCA GCGAGGACGT CCCAACGGCC 
AACAGAATCT TGATCCGTGT GATGTACTGT GGCCTCTGAA GCTATGGCCT TCGGTACATT 
CTACTGAAAA AGACCCTGGA GCATCAATTT CCAAACCTTC TGGAGTTTGA GGAGGAAAGA 
GCTACCCAGG TTACAGGGGA GTTTGAAGTG TTTGTGGATG GGAAATTGAT CCATTCCAAG 
AAGAAAGGCG ATGGCTTTGT GGATGAGACT AGTCTGAAGA AACTTGTGGG TGCTATTGAT 
GAAGAGATCA AGAAAAGGTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Selenoprotein Gene Nomenclature.
The Journal of biological chemistry291(46)24036-24040(2016 Nov)
Gladyshev VN,Arn?r ES,Berry MJ,Brigelius-Floh? R,Bruford EA,Burk RF,Carlson BA,Castellano S,Chavatte L,Conrad M,Copeland PR,Diamond AM,Driscoll DM,Ferreiro A,Floh? L,Green FR,Guig? R,Handy DE,Hatfield DL,Hesketh J,Hoffmann PR,Holmgren A,Hondal RJ,Howard MT,Huang K,Kim HY,Kim IY,K?hrle J,Krol A,Kryukov GV,Lee BJ,Lee BC,Lei XG,Liu Q,Lescure A,Lobanov AV,Loscalzo J,Maiorino M,Mariotti M,Sandeep Prabhu K,Rayman MP,Rozovsky S,Salinas G,Schmidt EE,Schomburg L,Schweizer U,Simonovi? M,Sunde RA,Tsuji PA,Tweedie S,Ursini F,Whanger PD,Zhang Y

[The search of partners of a new mammalian selenium-containing protein V (SelV) and expression it's mRNA during ontogenesis and spermatogenesis].
Molekuliarnaia biologiia46(2)276-84(2012 Mar-Apr)
Varlamova EG,Novoselov VI

Composition and evolution of the vertebrate and mammalian selenoproteomes.
PloS one7(3)e33066(2012)
Mariotti M,Ridge PG,Zhang Y,Lobanov AV,Pringle TH,Guigo R,Hatfield DL,Gladyshev VN

Characterization of mammalian selenoproteomes.
Science (New York, N.Y.)300(5624)1439-43(2003 May)
Kryukov GV,Castellano S,Novoselov SV,Lobanov AV,Zehtab O,Guig? R,Gladyshev VN

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Selenov cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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