Hoxb7 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Hoxb7
Entrez Gene ID	497985
Full Name	homeo box B7
Synonyms	Hox2r1b,R1b
General protein information	Preferred Names homeo box B7 Names homeobox protein Hox-B7 homeobox gene B7 homeobox protein R1B
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 10 Map Location: 10q26
Summary	mouse homolog is a DNA-binding homeobox transcription factor; may play a role in development of the haemopoietic system [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_001017480.1	NP_001017480.1	homeobox protein Hox-B7

Pathways from BioSystems

Homologies

	HOXB7	XP_001088822.1
Rattus norvegicus (Norway rat)	Hoxb7	NP_001017480.1
Pan troglodytes (chimpanzee)	HOXB7	XP_511938.3
Mus musculus (house mouse)	Hoxb7	NP_034590.2
Homo sapiens (human)	HOXB7	NP_004493.3
Bos taurus (cattle)	HOXB7	NP_776767.1
Danio rerio (zebrafish)	hoxb7a	NP_001108563.1
Xenopus tropicalis (tropical clawed frog)	LOC100494663	XP_002938071.2
Canis lupus familiaris (dog)	HOXB7	XP_851221.1
Gallus gallus (chicken)	HOXB7	XP_003642838.2

Gene Ontology
Bibliography

Related articles in PubMed

Deregulated HOXB7 Expression Predicts Poor Prognosis of Patients with Esophageal Squamous Cell Carcinoma and Regulates Cancer Cell Proliferation In Vitro and In Vivo.
Li H, Shen LY, Yan WP, Dong B, Kang XZ, Dai L, Yang YB, Fu H, Yang HL, Zhou HT, Huang C, Liang Z, Xiong HC, Chen KN
PloS one10(6)e0130551(2015)

Role of HOXB7 in regulation of progression and metastasis of human lung adenocarcinoma.
Yuan W, Zhang X, Xu Y, Li S, Hu Y, Wu S
Molecular carcinogenesis53(1)49-57(2014 Jan)

Vesico-ureteric reflux and urinary tract development in the Pax2 1Neu+/- mouse.
Murawski IJ, Myburgh DB, Favor J, Gupta IR
American journal of physiology. Renal physiology293(5)F1736-45(2007 Nov)

HOXB7, a homeodomain protein, is overexpressed in breast cancer and confers epithelial-mesenchymal transition.
Wu X, Chen H, Parker B, Rubin E, Zhu T, Lee JS, Argani P, Sukumar S
Cancer research66(19)9527-34(2006 Oct)

A large targeted deletion of Hoxb1-Hoxb9 produces a series of single-segment anterior homeotic transformations.
Medina-Mart?nez O, Bradley A, Ram?rez-Solis R
Developmental biology222(1)71-83(2000 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Hoxb7 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Hoxb7 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa05953	NM_001017480.1 Latest version!	Rattus norvegicus homeo box B7 (Hoxb7), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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2-4 Clone	40% OFF
5 or more Clone	50% OFF
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*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Hoxb7 ( NM_001017480.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001017480.1 Rattus norvegicus homeo box B7 (Hoxb7), mRNA.

Price & Availability↑

CloneID	ORa05953
Clone ID Related Accession (Same CDS sequence)	NM_001017480.1
Accession Version	NM_001017480.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 660bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-19
Organism	Rattus norvegicus(Norway rat)
Product	homeobox protein Hox-B7
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC079340.1. On Apr 29, 2005 this sequence version replaced XM_573181.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC079340.1, CK480314.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2689597, SAMEA2689601 [ECO:0000348] ##Evidence-Data-END##

ATGAGTTCAT TGTATTATGC GAATGCTTTA TTTTCTAAAT ATCCAGCCGC AAGTTCGGTT 
TTCGCTCCAG GAGCCTTCCC CGAACAAACT TCTTGCGCCT TTGCCTCCAA CCCCCAGCGC 
CCGGGCTATG GAGCAGGTCC GGGCGCCCCC TTCTCCGCCT CGGTGCAGGG TCTGTACTCC 
GGCGGTGGGG GCATGGCGGG CCAGAGCGCG GCCGGCGTCT ATGAGGCCGG CTACGGGCTC 
GAACCGAGTT CCTTCAACAT GCACTGCGCG CCCTTTGAGC AGAACCTCTC CGGGGTGTGT 
CCGGGCGACC CCGCCAAGGC GGCTGGCGCC AAGGAGCAGA GGGACTCGGA CTTGGCGGCC 
GAGAGTAACT TCCGGATCTA CCCCTGGATG CGAAGCTCAG GGACTGAACG AAAGCGGGGC 
CGCCAGACCT ATACGCGCTA CCAGACCCTG GAGCTGGAGA AAGAATTTCA CTACAATCGC 
TACCTGACTC GGCGGCGGCG CATCGAGATC GCGCACGCGC TCTGCCTCAC CGAAAGACAG 
ATCAAGATCT GGTTTCAGAA CCGGCGCATG AAGTGGAAAA AGGAGAACAA AACTTCAGGC 
CCAGGAACCA CTGGCCAGGA CAAGGCGGAA GCGGACGAGG AGGAAGAGGA GGAAGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001017480.1
CDS	20..679
Translation	MSSLYYANALFSKYPAASSVFAPGAFPEQTSCAFASNPQRPGYGAGPGAPFSASVQGLYSGGGGMAGQSAAGVYEAGYGLEPSSFNMHCAPFEQNLSGVCPGDPAKAAGAKEQRDSDLAAESNFRIYPWMRSSGTERKRGRQTYTRYQTLELEKEFHYNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKENKTSGPGTTGQDKAEADEEEEEEE

Target ORF information:

RefSeq Version	NM_001017480.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus homeo box B7 (Hoxb7), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001017480.1

ORF Insert Sequence:

ATGAGTTCAT TGTATTATGC GAATGCTTTA TTTTCTAAAT ATCCAGCCGC AAGTTCGGTT 
TTCGCTCCAG GAGCCTTCCC CGAACAAACT TCTTGCGCCT TTGCCTCCAA CCCCCAGCGC 
CCGGGCTATG GAGCAGGTCC GGGCGCCCCC TTCTCCGCCT CGGTGCAGGG TCTGTACTCC 
GGCGGTGGGG GCATGGCGGG CCAGAGCGCG GCCGGCGTCT ATGAGGCCGG CTACGGGCTC 
GAACCGAGTT CCTTCAACAT GCACTGCGCG CCCTTTGAGC AGAACCTCTC CGGGGTGTGT 
CCGGGCGACC CCGCCAAGGC GGCTGGCGCC AAGGAGCAGA GGGACTCGGA CTTGGCGGCC 
GAGAGTAACT TCCGGATCTA CCCCTGGATG CGAAGCTCAG GGACTGAACG AAAGCGGGGC 
CGCCAGACCT ATACGCGCTA CCAGACCCTG GAGCTGGAGA AAGAATTTCA CTACAATCGC 
TACCTGACTC GGCGGCGGCG CATCGAGATC GCGCACGCGC TCTGCCTCAC CGAAAGACAG 
ATCAAGATCT GGTTTCAGAA CCGGCGCATG AAGTGGAAAA AGGAGAACAA AACTTCAGGC 
CCAGGAACCA CTGGCCAGGA CAAGGCGGAA GCGGACGAGG AGGAAGAGGA GGAAGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Deregulated HOXB7 Expression Predicts Poor Prognosis of Patients with Esophageal Squamous Cell Carcinoma and Regulates Cancer Cell Proliferation In Vitro and In Vivo.
PloS one10(6)e0130551(2015)
Li H,Shen LY,Yan WP,Dong B,Kang XZ,Dai L,Yang YB,Fu H,Yang HL,Zhou HT,Huang C,Liang Z,Xiong HC,Chen KN

Role of HOXB7 in regulation of progression and metastasis of human lung adenocarcinoma.
Molecular carcinogenesis53(1)49-57(2014 Jan)
Yuan W,Zhang X,Xu Y,Li S,Hu Y,Wu S

Vesico-ureteric reflux and urinary tract development in the Pax2 1Neu+/- mouse.
American journal of physiology. Renal physiology293(5)F1736-45(2007 Nov)
Murawski IJ,Myburgh DB,Favor J,Gupta IR

HOXB7, a homeodomain protein, is overexpressed in breast cancer and confers epithelial-mesenchymal transition.
Cancer research66(19)9527-34(2006 Oct)
Wu X,Chen H,Parker B,Rubin E,Zhu T,Lee JS,Argani P,Sukumar S

A large targeted deletion of Hoxb1-Hoxb9 produces a series of single-segment anterior homeotic transformations.
Developmental biology222(1)71-83(2000 Jun)
Medina-Mart?nez O,Bradley A,Ram?rez-Solis R