Tgm3 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Tgm3
Entrez Gene ID	366189
Full Name	transglutaminase 3
Synonyms	RGD1561831,TG(E),TGE
General protein information	Preferred Names transglutaminase 3 Names protein-glutamine gamma-glutamyltransferase E TGase E TGase-3 glutamine gamma-glutamyltransferase E transglutaminase 3, E polypeptide transglutaminase E
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 3 Map Location: 3q36

mRNA and Protein(s)

mRNA	Protein	Name
NM_001108959.1	NP_001102429.1	protein-glutamine gamma-glutamyltransferase E

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	TGM3	XP_005634933.1
Mus musculus (house mouse)	Tgm3	NP_033400.2
Gallus gallus (chicken)	TGM3	XP_417392.3
	TGM3	XP_001113845.1
Rattus norvegicus (Norway rat)	Tgm3	NP_001102429.1
Xenopus tropicalis (tropical clawed frog)	tgm6	NP_001120399.1
Homo sapiens (human)	TGM3	NP_003236.3
Pan troglodytes (chimpanzee)	TGM3	XP_514468.2
Bos taurus (cattle)	TGM3	NP_001095318.1

Gene Ontology
Bibliography

Related articles in PubMed

Mutations in Three Genes Encoding Proteins Involved in Hair Shaft Formation Cause Uncombable Hair Syndrome.
? Basmanav FB, Cau L, Tafazzoli A, M?chin MC, Wolf S, Romano MT, Valentin F, Wiegmann H, Huchenq A, Kandil R, Garcia Bartels N, Kilic A, George S, Ralser DJ, Bergner S, Ferguson DJP, Oprisoreanu AM, Wehner M, Thiele H, Altm?ller J, N?rnberg P, Swan D, Houniet D, B?chner A, Weibel L, Wagner N, Grimalt R, Bygum A, Serre G, Blume-Peytavi U, Sprecher E, Schoch S, Oji V, Hamm H, Farrant P, Simon M, Betz RC
American journal of human genetics99(6)1292-1304(2016 Dec)

Hornerin is a component of the epidermal cornified cell envelopes.
Henry J, Hsu CY, Haftek M, Nachat R, de Koning HD, Gardinal-Galera I, Hitomi K, Balica S, Jean-Decoster C, Schmitt AM, Paul C, Serre G, Simon M
FASEB journal : official publication of the Federation of American Societies for Experimental Biology25(5)1567-76(2011 May)

Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).
Gonzalez-Begne M, Lu B, Han X, Hagen FK, Hand AR, Melvin JE, Yates JR
Journal of proteome research8(3)1304-14(2009 Mar)

Analysis of epidermal-type transglutaminase (transglutaminase 3) in human stratified epithelia and cultured keratinocytes using monoclonal antibodies.
Hitomi K, Presland RB, Nakayama T, Fleckman P, Dale BA, Maki M
Journal of dermatological science32(2)95-103(2003 Aug)

Roles of calcium ions in the activation and activity of the transglutaminase 3 enzyme.
Ahvazi B, Boeshans KM, Idler W, Baxa U, Steinert PM
The Journal of biological chemistry278(26)23834-41(2003 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Tgm3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Tgm3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa13760	NM_001108959.1 Latest version!	Rattus norvegicus transglutaminase 3 (Tgm3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Tgm3 ( NM_001108959.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001102429.1 Rattus norvegicus transglutaminase 3 (Tgm3), mRNA.

Price & Availability↑

CloneID	ORa13760
Clone ID Related Accession (Same CDS sequence)	NM_001108959.1
Accession Version	NM_001108959.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2082bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-19
Organism	Rattus norvegicus(Norway rat)
Product	protein-glutamine gamma-glutamyltransferase E
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473949.1. On or before Oct 4, 2007 this sequence version replaced XM_345432.3, XM_001079010.1. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA2689602, SAMN02642779 [ECO:0000348] ##Evidence-Data-END##

ATGAGTGCTT TAGAGGTCCA AAACATCAAC TGGCAGATGC CAATGAATCG AAGGGCACAT 
CACACAGACA AGTTCTCCAG CCAAGATTTC ATTGTACGGA GAGGACAGCC CTGGGAGGTA 
ATACTGCTCT GCAACCGAAG TCTTGAGTCT GGAGACAATC TGAACTTCAT CGTTTCCACA 
GGTCCCCAGC CCTCTGAGTC AGCCAGGACA AAGGCTGTAT TTTCCATCTC TGGGAGAAAT 
ACAAGTGGCT GGAGTGCAGC GCTCAAAGCC AGCAATGGCA ATAATCTGTT CATTGCTATT 
GCCAGTCCTG TCAGCGCTCC CATCGGATTG TACACACTGA ATGTTGAGGT CTCCTCCAAG 
GGCAGGGTCT CCTCTGTGAA ACTTGGCACA TTCACAGTGC TCTTCAACCC ATGGCAACAA 
GGGGATGATG TCTTTATGAG TAACCATGCT GAAAGACAAG AGTATGTTGA GGAAGATTCT 
GGCATCATCT ACGTGGGCAG CACAAATCGA ATTGGCATGG TTGGCTGGAA CTTTGGACAG 
TTTGAAGAAG ATATTCTGAG CATCAGCCTC TCCATTTTGG ATAGAAGTCT GAATTTCCGT 
CGTGACCCGG CGACTGATGT GGCCCGCAGA AATGATCCCA AATATGTTTG CCGGGTGCTG 
AGTGCCATGA TTAATGCCAA TGACGACAGC GGCGTTCTTT CTGGGAATTG GAGCGGTAAC 
TACAGCGGTG GTGTAGACCC AAGAACCTGG AACGGTAGTG TGGAGATCCT CAAGAACTGG 
AAAAAATCTG GCTTCAGACC AGTCCAATTT GGCCAGTGCT GGGTCTTTGC TGGGACCCTC 
AACACAGTGC TGCGGTGCTT GGGGGTTCCC TCTCGGGTGA TCACCAACTT CAACTCAGCT 
CACGACACAG ATCGCAACCT CAGTGTGGAT GTGTACTATG ACGCCATGGG AAATCCCTTG 
GAGAAAGGCA GTGATAGCGT GTGGAATTTT CATGTCTGGA ATGAAGGATG GTTCGTGCGG 
ACTGACCTAG GTCCCTCATA CAACGGATGG CAGGTGCTGG ATGCCACCCC TCAGGAGAGA 
AGTCAAGGTG TGTTCCAGTG TGGTCCTGCT TCCGTTAATG CAATCAAAGA TGGTGAGGTG 
GACCAGAACT TCGACATGAT CTTCATCTTC GCGGAGGTTA ACGCTGATCG CATCACTTGG 
ATCTACAATA ATAGGGATGG CAGCCAGAAG CAGAATTCTG TGGATACTTA CTCCATTGGC 
AAATACATCA GCACCAAGGC AGTAGGCAGC AACTCTCGCA TGGATGTCAC GATCAAGTAC 
AAGCACCCAG AAGGTTCCAA GGAGGAAAGA CAAGTGCAGC AAAAGGCTAT GAACAAACTC 
AAACCTAATG CATCTTTTGG CGCAACGTCT TCGAGGGGTC CCCAGGGGGA AGAAAAGGAG 
CCCAGCATTT CTGGGAAGTT CAAGGTCACT GGGGTACTGG CAGTAGGCAA AGAAGTCAGT 
CTGGCCCTGA TACTCAAAAA CACGACTAGT GATAGGAAGA CAGTGACAAC AAATATGACA 
GCCTGGACCA TCGTCTACAA TGGTACCCTT GTCCACGAAG TGTGGAAGGA CTCTGCCACA 
ATATCCTTGG ATCCTGAAGA AGAAATACAG TATCCAGTGA AGATTGCATA CTCTCAGTAT 
GATAGATACC TAAAGGCAGA CAACATGATC CGGATCACAG CCGTATGCAA GGTGCCTGAT 
GAGGCTGAGG TGGTCGTGGA GCGGGATGTC ATCCTGGACA ACCCCACTTT GACCCTGGAG 
GTGCTGGACC AGGCTCAGTT ACGAAAGCCG GTGGTCGTGC AGATGCTTTT CTCCAACCCC 
CTGGATGAAC CAGTGAAGAA CTGTGTGCTG ATGGTGGAAG GCAGTGGCCT GCTGCGTGGC 
AGCCTCAAAA TCGATGTGCC GGCCCTGCGC CCCAAGGAGA AGTCCCGGGT CCGATTTGAG 
ATTTTCCCCA CTCGGATTGG CATCAAGCAA CTGCTGGCCG ACTTTTCCTG CAATAAATTC 
CCTGCAATCA AGGCCATGCT GGTCATTGAG GTGTCCGAGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001102429.1
CDS	55..2136
Translation	MSALEVQNINWQMPMNRRAHHTDKFSSQDFIVRRGQPWEVILLCNRSLESGDNLNFIVSTGPQPSESARTKAVFSISGRNTSGWSAALKASNGNNLFIAIASPVSAPIGLYTLNVEVSSKGRVSSVKLGTFTVLFNPWQQGDDVFMSNHAERQEYVEEDSGIIYVGSTNRIGMVGWNFGQFEEDILSISLSILDRSLNFRRDPATDVARRNDPKYVCRVLSAMINANDDSGVLSGNWSGNYSGGVDPRTWNGSVEILKNWKKSGFRPVQFGQCWVFAGTLNTVLRCLGVPSRVITNFNSAHDTDRNLSVDVYYDAMGNPLEKGSDSVWNFHVWNEGWFVRTDLGPSYNGWQVLDATPQERSQGVFQCGPASVNAIKDGEVDQNFDMIFIFAEVNADRITWIYNNRDGSQKQNSVDTYSIGKYISTKAVGSNSRMDVTIKYKHPEGSKEERQVQQKAMNKLKPNASFGATSSRGPQGEEKEPSISGKFKVTGVLAVGKEVSLALILKNTTSDRKTVTTNMTAWTIVYNGTLVHEVWKDSATISLDPEEEIQYPVKIAYSQYDRYLKADNMIRITAVCKVPDEAEVVVERDVILDNPTLTLEVLDQAQLRKPVVVQMLFSNPLDEPVKNCVLMVEGSGLLRGSLKIDVPALRPKEKSRVRFEIFPTRIGIKQLLADFSCNKFPAIKAMLVIEVSE

Target ORF information:

RefSeq Version	NM_001108959.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus transglutaminase 3 (Tgm3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001108959.1

ORF Insert Sequence:

ATGAGTGCTT TAGAGGTCCA AAACATCAAC TGGCAGATGC CAATGAATCG AAGGGCACAT 
CACACAGACA AGTTCTCCAG CCAAGATTTC ATTGTACGGA GAGGACAGCC CTGGGAGGTA 
ATACTGCTCT GCAACCGAAG TCTTGAGTCT GGAGACAATC TGAACTTCAT CGTTTCCACA 
GGTCCCCAGC CCTCTGAGTC AGCCAGGACA AAGGCTGTAT TTTCCATCTC TGGGAGAAAT 
ACAAGTGGCT GGAGTGCAGC GCTCAAAGCC AGCAATGGCA ATAATCTGTT CATTGCTATT 
GCCAGTCCTG TCAGCGCTCC CATCGGATTG TACACACTGA ATGTTGAGGT CTCCTCCAAG 
GGCAGGGTCT CCTCTGTGAA ACTTGGCACA TTCACAGTGC TCTTCAACCC ATGGCAACAA 
GGGGATGATG TCTTTATGAG TAACCATGCT GAAAGACAAG AGTATGTTGA GGAAGATTCT 
GGCATCATCT ACGTGGGCAG CACAAATCGA ATTGGCATGG TTGGCTGGAA CTTTGGACAG 
TTTGAAGAAG ATATTCTGAG CATCAGCCTC TCCATTTTGG ATAGAAGTCT GAATTTCCGT 
CGTGACCCGG CGACTGATGT GGCCCGCAGA AATGATCCCA AATATGTTTG CCGGGTGCTG 
AGTGCCATGA TTAATGCCAA TGACGACAGC GGCGTTCTTT CTGGGAATTG GAGCGGTAAC 
TACAGCGGTG GTGTAGACCC AAGAACCTGG AACGGTAGTG TGGAGATCCT CAAGAACTGG 
AAAAAATCTG GCTTCAGACC AGTCCAATTT GGCCAGTGCT GGGTCTTTGC TGGGACCCTC 
AACACAGTGC TGCGGTGCTT GGGGGTTCCC TCTCGGGTGA TCACCAACTT CAACTCAGCT 
CACGACACAG ATCGCAACCT CAGTGTGGAT GTGTACTATG ACGCCATGGG AAATCCCTTG 
GAGAAAGGCA GTGATAGCGT GTGGAATTTT CATGTCTGGA ATGAAGGATG GTTCGTGCGG 
ACTGACCTAG GTCCCTCATA CAACGGATGG CAGGTGCTGG ATGCCACCCC TCAGGAGAGA 
AGTCAAGGTG TGTTCCAGTG TGGTCCTGCT TCCGTTAATG CAATCAAAGA TGGTGAGGTG 
GACCAGAACT TCGACATGAT CTTCATCTTC GCGGAGGTTA ACGCTGATCG CATCACTTGG 
ATCTACAATA ATAGGGATGG CAGCCAGAAG CAGAATTCTG TGGATACTTA CTCCATTGGC 
AAATACATCA GCACCAAGGC AGTAGGCAGC AACTCTCGCA TGGATGTCAC GATCAAGTAC 
AAGCACCCAG AAGGTTCCAA GGAGGAAAGA CAAGTGCAGC AAAAGGCTAT GAACAAACTC 
AAACCTAATG CATCTTTTGG CGCAACGTCT TCGAGGGGTC CCCAGGGGGA AGAAAAGGAG 
CCCAGCATTT CTGGGAAGTT CAAGGTCACT GGGGTACTGG CAGTAGGCAA AGAAGTCAGT 
CTGGCCCTGA TACTCAAAAA CACGACTAGT GATAGGAAGA CAGTGACAAC AAATATGACA 
GCCTGGACCA TCGTCTACAA TGGTACCCTT GTCCACGAAG TGTGGAAGGA CTCTGCCACA 
ATATCCTTGG ATCCTGAAGA AGAAATACAG TATCCAGTGA AGATTGCATA CTCTCAGTAT 
GATAGATACC TAAAGGCAGA CAACATGATC CGGATCACAG CCGTATGCAA GGTGCCTGAT 
GAGGCTGAGG TGGTCGTGGA GCGGGATGTC ATCCTGGACA ACCCCACTTT GACCCTGGAG 
GTGCTGGACC AGGCTCAGTT ACGAAAGCCG GTGGTCGTGC AGATGCTTTT CTCCAACCCC 
CTGGATGAAC CAGTGAAGAA CTGTGTGCTG ATGGTGGAAG GCAGTGGCCT GCTGCGTGGC 
AGCCTCAAAA TCGATGTGCC GGCCCTGCGC CCCAAGGAGA AGTCCCGGGT CCGATTTGAG 
ATTTTCCCCA CTCGGATTGG CATCAAGCAA CTGCTGGCCG ACTTTTCCTG CAATAAATTC 
CCTGCAATCA AGGCCATGCT GGTCATTGAG GTGTCCGAGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Mutations in Three Genes Encoding Proteins Involved in Hair Shaft Formation Cause Uncombable Hair Syndrome.
American journal of human genetics99(6)1292-1304(2016 Dec)
? Basmanav FB,Cau L,Tafazzoli A,M?chin MC,Wolf S,Romano MT,Valentin F,Wiegmann H,Huchenq A,Kandil R,Garcia Bartels N,Kilic A,George S,Ralser DJ,Bergner S,Ferguson DJP,Oprisoreanu AM,Wehner M,Thiele H,Altm?ller J,N?rnberg P,Swan D,Houniet D,B?chner A,Weibel L,Wagner N,Grimalt R,Bygum A,Serre G,Blume-Peytavi U,Sprecher E,Schoch S,Oji V,Hamm H,Farrant P,Simon M,Betz RC

Hornerin is a component of the epidermal cornified cell envelopes.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology25(5)1567-76(2011 May)
Henry J,Hsu CY,Haftek M,Nachat R,de Koning HD,Gardinal-Galera I,Hitomi K,Balica S,Jean-Decoster C,Schmitt AM,Paul C,Serre G,Simon M

Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).
Journal of proteome research8(3)1304-14(2009 Mar)
Gonzalez-Begne M,Lu B,Han X,Hagen FK,Hand AR,Melvin JE,Yates JR

Analysis of epidermal-type transglutaminase (transglutaminase 3) in human stratified epithelia and cultured keratinocytes using monoclonal antibodies.
Journal of dermatological science32(2)95-103(2003 Aug)
Hitomi K,Presland RB,Nakayama T,Fleckman P,Dale BA,Maki M

Roles of calcium ions in the activation and activity of the transglutaminase 3 enzyme.
The Journal of biological chemistry278(26)23834-41(2003 Jun)
Ahvazi B,Boeshans KM,Idler W,Baxa U,Steinert PM