Taz cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Taz
Entrez Gene ID	363521
Full Name	tafazzin
General protein information	Preferred Names tafazzin Names tafazzin Barth syndrome) cardiomyopathy, dilated 3A (X-linked) endocardial fibroelastosis 2 tafazzin (cardiomyopathy, dilated 3A (X-linked) tafazzin (cardiomyopathy, dilated 3A (X-linked); endocardial fibroelastosis 2; Barth syndrome)
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: X Map Location: Xq37
Summary	human homolog may play a role in cardiolipin metabolism [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_001025748.1	NP_001020919.1	tafazzin
XM_006229600.3	XP_006229662.1	tafazzin isoform X1
XM_006229599.3	XP_006229661.1	tafazzin isoform X1
XM_017602118.1	XP_017457607.1	tafazzin isoform X2

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Taz	NP_001020919.1
Kluyveromyces lactis	KLLA0B10978g	XP_452017.1
Drosophila melanogaster (fruit fly)	Taz	NP_001188916.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP007599	XP_308273.4
Danio rerio (zebrafish)	taz	NP_001001814.1
Saccharomyces cerevisiae (baker's yeast)	TAZ1	NP_015466.1
Neurospora crassa	NCU07576	XP_958270.1
Mus musculus (house mouse)	Taz	NP_001167018.1
Caenorhabditis elegans (roundworm)	acl-3	NP_502202.2
Eremothecium gossypii	AGOS_AGR254C	NP_986920.1
Magnaporthe oryzae (rice blast fungus)	MGG_04664	XP_003713659.1
Homo sapiens (human)	TAZ	NP_000107.1
	TAZ	NP_001028086.1
Canis lupus familiaris (dog)	TAZ	XP_005642085.1
Bos taurus (cattle)	TAZ	XP_002699760.1
Arabidopsis thaliana (thale cress)	AT3G05510	NP_566254.1
Oryza sativa (rice)	Os01g0931300	NP_001045296.2
Xenopus tropicalis (tropical clawed frog)	taz	NP_001016466.1

Gene Ontology
Bibliography

Related articles in PubMed

Effects of siRNA-dependent knock-down of cardiolipin synthase and tafazzin on mitochondria and proliferation of glioma cells.
Ohlig T, Le DV, Gardemann A, Wolke C, G?rtler S, Peter D, Schild L, Lendeckel U
Biochimica et biophysica acta(2018 Jan)

Metabolism and function of mitochondrial cardiolipin.
Ren M, Phoon CK, Schlame M
Progress in lipid research551-16(2014 Jul)

Tafazzin knockdown interrupts cell cycle progression in cultured neonatal ventricular fibroblasts.
He Q, Wang M, Harris N, Han X
American journal of physiology. Heart and circulatory physiology305(9)H1332-43(2013 Nov)

Nek1 and TAZ interact to maintain normal levels of polycystin 2.
Yim H, Sung CK, You J, Tian Y, Benjamin T
Journal of the American Society of Nephrology : JASN22(5)832-7(2011 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Overexpression of CHTRC1 increased osteogenic differentiation of periodontal ligament stem cells, which could be abolished by TAZ siRNA.
Title: CTHRC1 promotes osteogenic differentiation of periodontal ligament stem cells by regulating TAZ.

Mechanisms that underlie neuropathic pain remain elusive. We have demonstrated recently that nerve injury can activate Wnt signaling, which becomes a trigger for the development of neuropathic pain. We report that transcriptional regulators YAP and TAZ, which orchestrate Wnt response via incorporation in the beta-catenin destruction complex, are key in the pathogenesis of neuropathic pain and may serve as an "ON-OFF" s...
Title: Inhibition of YAP/TAZ Activity in Spinal Cord Suppresses Neuropathic Pain.

Tafazzin knockdown interrupts the neonatal ventricular fibroblast cell cycle and this in turn may contribute to fibrosis and dilated cardiomyopathy in Barth syndrome.
Title: Tafazzin knockdown interrupts cell cycle progression in cultured neonatal ventricular fibroblasts.

Data support the concept that a decreased tafazzin expression causes cardiomyocyte hypertrophy in vitro.
Title: Tafazzin knockdown causes hypertrophy of neonatal ventricular myocytes.

The following Taz gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Taz cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa13677	NM_001025748.1 Latest version!	Rattus norvegicus tafazzin (Taz), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
ORa13677	XM_006229600.3 Latest version!	Rattus norvegicus tafazzin (Taz), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
ORa13677	XM_006229599.3 Latest version!	Rattus norvegicus tafazzin (Taz), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
ORa63086	XM_017602118.1 Latest version!	Rattus norvegicus tafazzin (Taz), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
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*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Taz ( NM_001025748.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001020919.1 Rattus norvegicus tafazzin (Taz), mRNA.

Price & Availability↑

CloneID	ORa13677
Clone ID Related Accession (Same CDS sequence)	NM_001025748.1 , XM_006229600.3 , XM_006229599.3
Accession Version	NM_001025748.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 789bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-20
Organism	Rattus norvegicus(Norway rat)
Product	tafazzin
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC099221.1. On Jul 22, 2005 this sequence version replaced XM_343845.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC099221.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01906348 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END##

ATGCCCCTCC ACGTGAAGTG GCCATTCCCC GCGGTGCCCC GACTCACCTG GACCCTAGCC 
AGCAGTGTCG TCATGGGTCT AGTTGGCACC TACAGCTGCT TCTGGACCAA GTATATGAAC 
CACCTTACCG TGTACAACAA GGAAGTGCTG TATGAGCTCA TTGAGAACCG AGGTCCTGCG 
ACCCCTCTTA TCACCGTCTC TAACCACCAG TCTTGCATGG ATGACCCTCA TCTCTGGGGG 
ATCCTGAAAC TCCGCCACAT CTGGAACCTG AAGTTGATGC GTTGGACCCC AGCAGCTGCA 
GACATCTGCT TCACCAAGGA GCTGCATTCC CATTTCTTCA GCTTGGGCAA ATGTGTGCCT 
GTATGTCGAG GAGATGGTGT CTATCAGAAA GGGATGGACT TCATTTTGGA GAAGCTTAAC 
CATGGGGACT GGGTACACAT CTTTCCAGAA GGAAAAGTAA ACATGAGTTC TGAGTTCCTG 
CGCTTCAAAT GGGGAATTGG ACGGCTGATT GCTGAGTGTC ATCTAAACCC CATCATCCTG 
CCACTATGGC ATGTTGGAAT GAATGATGTC CTCCCTAACA GTCCACCCTA CTTCCCCCGC 
TTTGGACAGA AAATCACCGT GCTGATTGGG AAGCCCTTCA GTACACTCCC TGTGCTTGAG 
CGGCTCCGGG CAGAAAACAA GTCAGCTGTG GAGATGCGGA AAGCCCTCAC AGACTTCATT 
CAAGAGGAAT TCCAGCGGCT GAAGATGCAG GCAGAACAGC TCCACAATCA TTTCCAGCCT 
GGAAGATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001020919.1
CDS	248..1036
Translation	MPLHVKWPFPAVPRLTWTLASSVVMGLVGTYSCFWTKYMNHLTVYNKEVLYELIENRGPATPLITVSNHQSCMDDPHLWGILKLRHIWNLKLMRWTPAAADICFTKELHSHFFSLGKCVPVCRGDGVYQKGMDFILEKLNHGDWVHIFPEGKVNMSSEFLRFKWGIGRLIAECHLNPIILPLWHVGMNDVLPNSPPYFPRFGQKITVLIGKPFSTLPVLERLRAENKSAVEMRKALTDFIQEEFQRLKMQAEQLHNHFQPGR

Target ORF information:

RefSeq Version	NM_001025748.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus tafazzin (Taz), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001025748.1

ORF Insert Sequence:

ATGCCCCTCC ACGTGAAGTG GCCATTCCCC GCGGTGCCCC GACTCACCTG GACCCTAGCC 
AGCAGTGTCG TCATGGGTCT AGTTGGCACC TACAGCTGCT TCTGGACCAA GTATATGAAC 
CACCTTACCG TGTACAACAA GGAAGTGCTG TATGAGCTCA TTGAGAACCG AGGTCCTGCG 
ACCCCTCTTA TCACCGTCTC TAACCACCAG TCTTGCATGG ATGACCCTCA TCTCTGGGGG 
ATCCTGAAAC TCCGCCACAT CTGGAACCTG AAGTTGATGC GTTGGACCCC AGCAGCTGCA 
GACATCTGCT TCACCAAGGA GCTGCATTCC CATTTCTTCA GCTTGGGCAA ATGTGTGCCT 
GTATGTCGAG GAGATGGTGT CTATCAGAAA GGGATGGACT TCATTTTGGA GAAGCTTAAC 
CATGGGGACT GGGTACACAT CTTTCCAGAA GGAAAAGTAA ACATGAGTTC TGAGTTCCTG 
CGCTTCAAAT GGGGAATTGG ACGGCTGATT GCTGAGTGTC ATCTAAACCC CATCATCCTG 
CCACTATGGC ATGTTGGAAT GAATGATGTC CTCCCTAACA GTCCACCCTA CTTCCCCCGC 
TTTGGACAGA AAATCACCGT GCTGATTGGG AAGCCCTTCA GTACACTCCC TGTGCTTGAG 
CGGCTCCGGG CAGAAAACAA GTCAGCTGTG GAGATGCGGA AAGCCCTCAC AGACTTCATT 
CAAGAGGAAT TCCAGCGGCT GAAGATGCAG GCAGAACAGC TCCACAATCA TTTCCAGCCT 
GGAAGATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Taz ( XM_006229600.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006229662.1 Rattus norvegicus tafazzin (Taz), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa13677
Clone ID Related Accession (Same CDS sequence)	NM_001025748.1 , XM_006229600.3 , XM_006229599.3
Accession Version	XM_006229600.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 789bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	tafazzin isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005120.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006229600.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCCCTCC ACGTGAAGTG GCCATTCCCC GCGGTGCCCC GACTCACCTG GACCCTAGCC 
AGCAGTGTCG TCATGGGTCT AGTTGGCACC TACAGCTGCT TCTGGACCAA GTATATGAAC 
CACCTTACCG TGTACAACAA GGAAGTGCTG TATGAGCTCA TTGAGAACCG AGGTCCTGCG 
ACCCCTCTTA TCACCGTCTC TAACCACCAG TCTTGCATGG ATGACCCTCA TCTCTGGGGG 
ATCCTGAAAC TCCGCCACAT CTGGAACCTG AAGTTGATGC GTTGGACCCC AGCAGCTGCA 
GACATCTGCT TCACCAAGGA GCTGCATTCC CATTTCTTCA GCTTGGGCAA ATGTGTGCCT 
GTATGTCGAG GAGATGGTGT CTATCAGAAA GGGATGGACT TCATTTTGGA GAAGCTTAAC 
CATGGGGACT GGGTACACAT CTTTCCAGAA GGAAAAGTAA ACATGAGTTC TGAGTTCCTG 
CGCTTCAAAT GGGGAATTGG ACGGCTGATT GCTGAGTGTC ATCTAAACCC CATCATCCTG 
CCACTATGGC ATGTTGGAAT GAATGATGTC CTCCCTAACA GTCCACCCTA CTTCCCCCGC 
TTTGGACAGA AAATCACCGT GCTGATTGGG AAGCCCTTCA GTACACTCCC TGTGCTTGAG 
CGGCTCCGGG CAGAAAACAA GTCAGCTGTG GAGATGCGGA AAGCCCTCAC AGACTTCATT 
CAAGAGGAAT TCCAGCGGCT GAAGATGCAG GCAGAACAGC TCCACAATCA TTTCCAGCCT 
GGAAGATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006229662.1
CDS	433..1221
Translation	MPLHVKWPFPAVPRLTWTLASSVVMGLVGTYSCFWTKYMNHLTVYNKEVLYELIENRGPATPLITVSNHQSCMDDPHLWGILKLRHIWNLKLMRWTPAAADICFTKELHSHFFSLGKCVPVCRGDGVYQKGMDFILEKLNHGDWVHIFPEGKVNMSSEFLRFKWGIGRLIAECHLNPIILPLWHVGMNDVLPNSPPYFPRFGQKITVLIGKPFSTLPVLERLRAENKSAVEMRKALTDFIQEEFQRLKMQAEQLHNHFQPGR

Target ORF information:

RefSeq Version	XM_006229600.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus tafazzin (Taz), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006229600.3

ORF Insert Sequence:

ATGCCCCTCC ACGTGAAGTG GCCATTCCCC GCGGTGCCCC GACTCACCTG GACCCTAGCC 
AGCAGTGTCG TCATGGGTCT AGTTGGCACC TACAGCTGCT TCTGGACCAA GTATATGAAC 
CACCTTACCG TGTACAACAA GGAAGTGCTG TATGAGCTCA TTGAGAACCG AGGTCCTGCG 
ACCCCTCTTA TCACCGTCTC TAACCACCAG TCTTGCATGG ATGACCCTCA TCTCTGGGGG 
ATCCTGAAAC TCCGCCACAT CTGGAACCTG AAGTTGATGC GTTGGACCCC AGCAGCTGCA 
GACATCTGCT TCACCAAGGA GCTGCATTCC CATTTCTTCA GCTTGGGCAA ATGTGTGCCT 
GTATGTCGAG GAGATGGTGT CTATCAGAAA GGGATGGACT TCATTTTGGA GAAGCTTAAC 
CATGGGGACT GGGTACACAT CTTTCCAGAA GGAAAAGTAA ACATGAGTTC TGAGTTCCTG 
CGCTTCAAAT GGGGAATTGG ACGGCTGATT GCTGAGTGTC ATCTAAACCC CATCATCCTG 
CCACTATGGC ATGTTGGAAT GAATGATGTC CTCCCTAACA GTCCACCCTA CTTCCCCCGC 
TTTGGACAGA AAATCACCGT GCTGATTGGG AAGCCCTTCA GTACACTCCC TGTGCTTGAG 
CGGCTCCGGG CAGAAAACAA GTCAGCTGTG GAGATGCGGA AAGCCCTCAC AGACTTCATT 
CAAGAGGAAT TCCAGCGGCT GAAGATGCAG GCAGAACAGC TCCACAATCA TTTCCAGCCT 
GGAAGATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Taz ( XM_006229599.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006229661.1 Rattus norvegicus tafazzin (Taz), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa13677
Clone ID Related Accession (Same CDS sequence)	NM_001025748.1 , XM_006229600.3 , XM_006229599.3
Accession Version	XM_006229599.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 789bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	tafazzin isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005120.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006229599.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCCCTCC ACGTGAAGTG GCCATTCCCC GCGGTGCCCC GACTCACCTG GACCCTAGCC 
AGCAGTGTCG TCATGGGTCT AGTTGGCACC TACAGCTGCT TCTGGACCAA GTATATGAAC 
CACCTTACCG TGTACAACAA GGAAGTGCTG TATGAGCTCA TTGAGAACCG AGGTCCTGCG 
ACCCCTCTTA TCACCGTCTC TAACCACCAG TCTTGCATGG ATGACCCTCA TCTCTGGGGG 
ATCCTGAAAC TCCGCCACAT CTGGAACCTG AAGTTGATGC GTTGGACCCC AGCAGCTGCA 
GACATCTGCT TCACCAAGGA GCTGCATTCC CATTTCTTCA GCTTGGGCAA ATGTGTGCCT 
GTATGTCGAG GAGATGGTGT CTATCAGAAA GGGATGGACT TCATTTTGGA GAAGCTTAAC 
CATGGGGACT GGGTACACAT CTTTCCAGAA GGAAAAGTAA ACATGAGTTC TGAGTTCCTG 
CGCTTCAAAT GGGGAATTGG ACGGCTGATT GCTGAGTGTC ATCTAAACCC CATCATCCTG 
CCACTATGGC ATGTTGGAAT GAATGATGTC CTCCCTAACA GTCCACCCTA CTTCCCCCGC 
TTTGGACAGA AAATCACCGT GCTGATTGGG AAGCCCTTCA GTACACTCCC TGTGCTTGAG 
CGGCTCCGGG CAGAAAACAA GTCAGCTGTG GAGATGCGGA AAGCCCTCAC AGACTTCATT 
CAAGAGGAAT TCCAGCGGCT GAAGATGCAG GCAGAACAGC TCCACAATCA TTTCCAGCCT 
GGAAGATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006229661.1
CDS	642..1430
Translation	MPLHVKWPFPAVPRLTWTLASSVVMGLVGTYSCFWTKYMNHLTVYNKEVLYELIENRGPATPLITVSNHQSCMDDPHLWGILKLRHIWNLKLMRWTPAAADICFTKELHSHFFSLGKCVPVCRGDGVYQKGMDFILEKLNHGDWVHIFPEGKVNMSSEFLRFKWGIGRLIAECHLNPIILPLWHVGMNDVLPNSPPYFPRFGQKITVLIGKPFSTLPVLERLRAENKSAVEMRKALTDFIQEEFQRLKMQAEQLHNHFQPGR

Target ORF information:

RefSeq Version	XM_006229599.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus tafazzin (Taz), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006229599.3

ORF Insert Sequence:

ATGCCCCTCC ACGTGAAGTG GCCATTCCCC GCGGTGCCCC GACTCACCTG GACCCTAGCC 
AGCAGTGTCG TCATGGGTCT AGTTGGCACC TACAGCTGCT TCTGGACCAA GTATATGAAC 
CACCTTACCG TGTACAACAA GGAAGTGCTG TATGAGCTCA TTGAGAACCG AGGTCCTGCG 
ACCCCTCTTA TCACCGTCTC TAACCACCAG TCTTGCATGG ATGACCCTCA TCTCTGGGGG 
ATCCTGAAAC TCCGCCACAT CTGGAACCTG AAGTTGATGC GTTGGACCCC AGCAGCTGCA 
GACATCTGCT TCACCAAGGA GCTGCATTCC CATTTCTTCA GCTTGGGCAA ATGTGTGCCT 
GTATGTCGAG GAGATGGTGT CTATCAGAAA GGGATGGACT TCATTTTGGA GAAGCTTAAC 
CATGGGGACT GGGTACACAT CTTTCCAGAA GGAAAAGTAA ACATGAGTTC TGAGTTCCTG 
CGCTTCAAAT GGGGAATTGG ACGGCTGATT GCTGAGTGTC ATCTAAACCC CATCATCCTG 
CCACTATGGC ATGTTGGAAT GAATGATGTC CTCCCTAACA GTCCACCCTA CTTCCCCCGC 
TTTGGACAGA AAATCACCGT GCTGATTGGG AAGCCCTTCA GTACACTCCC TGTGCTTGAG 
CGGCTCCGGG CAGAAAACAA GTCAGCTGTG GAGATGCGGA AAGCCCTCAC AGACTTCATT 
CAAGAGGAAT TCCAGCGGCT GAAGATGCAG GCAGAACAGC TCCACAATCA TTTCCAGCCT 
GGAAGATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Taz ( XM_017602118.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017457607.1 Rattus norvegicus tafazzin (Taz), transcript variant X3, mRNA.

Price & Availability↑

CloneID	ORa63086
Clone ID Related Accession (Same CDS sequence)	XM_017602118.1
Accession Version	XM_017602118.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 675bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	tafazzin isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005120.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAACCACC TTACCGTGTA CAACAAGGAA GTGCTGTATG AGCTCATTGA GAACCGAGGT 
CCTGCGACCC CTCTTATCAC CGTCTCTAAC CACCAGTCTT GCATGGATGA CCCTCATCTC 
TGGGGGATCC TGAAACTCCG CCACATCTGG AACCTGAAGT TGATGCGTTG GACCCCAGCA 
GCTGCAGACA TCTGCTTCAC CAAGGAGCTG CATTCCCATT TCTTCAGCTT GGGCAAATGT 
GTGCCTGTAT GTCGAGGAGA TGGTGTCTAT CAGAAAGGGA TGGACTTCAT TTTGGAGAAG 
CTTAACCATG GGGACTGGGT ACACATCTTT CCAGAAGGAA AAGTAAACAT GAGTTCTGAG 
TTCCTGCGCT TCAAATGGGG AATTGGACGG CTGATTGCTG AGTGTCATCT AAACCCCATC 
ATCCTGCCAC TATGGCATGT TGGAATGAAT GATGTCCTCC CTAACAGTCC ACCCTACTTC 
CCCCGCTTTG GACAGAAAAT CACCGTGCTG ATTGGGAAGC CCTTCAGTAC ACTCCCTGTG 
CTTGAGCGGC TCCGGGCAGA AAACAAGTCA GCTGTGGAGA TGCGGAAAGC CCTCACAGAC 
TTCATTCAAG AGGAATTCCA GCGGCTGAAG ATGCAGGCAG AACAGCTCCA CAATCATTTC 
CAGCCTGGAA GATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017457607.1
CDS	136..810
Translation	MNHLTVYNKEVLYELIENRGPATPLITVSNHQSCMDDPHLWGILKLRHIWNLKLMRWTPAAADICFTKELHSHFFSLGKCVPVCRGDGVYQKGMDFILEKLNHGDWVHIFPEGKVNMSSEFLRFKWGIGRLIAECHLNPIILPLWHVGMNDVLPNSPPYFPRFGQKITVLIGKPFSTLPVLERLRAENKSAVEMRKALTDFIQEEFQRLKMQAEQLHNHFQPGR

Target ORF information:

RefSeq Version	XM_017602118.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus tafazzin (Taz), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017602118.1

ORF Insert Sequence:

ATGAACCACC TTACCGTGTA CAACAAGGAA GTGCTGTATG AGCTCATTGA GAACCGAGGT 
CCTGCGACCC CTCTTATCAC CGTCTCTAAC CACCAGTCTT GCATGGATGA CCCTCATCTC 
TGGGGGATCC TGAAACTCCG CCACATCTGG AACCTGAAGT TGATGCGTTG GACCCCAGCA 
GCTGCAGACA TCTGCTTCAC CAAGGAGCTG CATTCCCATT TCTTCAGCTT GGGCAAATGT 
GTGCCTGTAT GTCGAGGAGA TGGTGTCTAT CAGAAAGGGA TGGACTTCAT TTTGGAGAAG 
CTTAACCATG GGGACTGGGT ACACATCTTT CCAGAAGGAA AAGTAAACAT GAGTTCTGAG 
TTCCTGCGCT TCAAATGGGG AATTGGACGG CTGATTGCTG AGTGTCATCT AAACCCCATC 
ATCCTGCCAC TATGGCATGT TGGAATGAAT GATGTCCTCC CTAACAGTCC ACCCTACTTC 
CCCCGCTTTG GACAGAAAAT CACCGTGCTG ATTGGGAAGC CCTTCAGTAC ACTCCCTGTG 
CTTGAGCGGC TCCGGGCAGA AAACAAGTCA GCTGTGGAGA TGCGGAAAGC CCTCACAGAC 
TTCATTCAAG AGGAATTCCA GCGGCTGAAG ATGCAGGCAG AACAGCTCCA CAATCATTTC 
CAGCCTGGAA GATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Effects of siRNA-dependent knock-down of cardiolipin synthase and tafazzin on mitochondria and proliferation of glioma cells.
Biochimica et biophysica acta(2018 Jan)
Ohlig T,Le DV,Gardemann A,Wolke C,G?rtler S,Peter D,Schild L,Lendeckel U

Metabolism and function of mitochondrial cardiolipin.
Progress in lipid research551-16(2014 Jul)
Ren M,Phoon CK,Schlame M

Tafazzin knockdown interrupts cell cycle progression in cultured neonatal ventricular fibroblasts.
American journal of physiology. Heart and circulatory physiology305(9)H1332-43(2013 Nov)
He Q,Wang M,Harris N,Han X

Nek1 and TAZ interact to maintain normal levels of polycystin 2.
Journal of the American Society of Nephrology : JASN22(5)832-7(2011 May)
Yim H,Sung CK,You J,Tian Y,Benjamin T

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Taz cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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