Atl1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Atl1
Entrez Gene ID	362750
Full Name	atlastin GTPase 1
Synonyms	Spg3a
General protein information	Preferred Names atlastin GTPase 1 Names atlastin-1 spastic paraplegia 3A homolog
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 6 Map Location: 6q24

mRNA and Protein(s)

mRNA	Protein	Name
NM_001009831.2	NP_001009831.1	atlastin-1
XM_017594227.1	XP_017449716.1	atlastin-1 isoform X1

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	ATL1	XP_005623439.1
	ATL1	XP_001101240.1
Gallus gallus (chicken)	ATL1	XP_421466.4
Pan troglodytes (chimpanzee)	ATL1	XP_001156076.1
Mus musculus (house mouse)	Atl1	NP_848743.1
Danio rerio (zebrafish)	atl1	NP_001139172.1
Xenopus tropicalis (tropical clawed frog)	atl1	NP_001072222.1
Homo sapiens (human)	ATL1	NP_056999.2
Bos taurus (cattle)	ATL1	NP_001029803.1
Rattus norvegicus (Norway rat)	Atl1	NP_001009831.1

Gene Ontology
Bibliography

Related articles in PubMed

Cooperation of the ER-shaping proteins atlastin, lunapark, and reticulons to generate a tubular membrane network.
Wang S, Tukachinsky H, Romano FB, Rapoport TA
eLife5(2016 09)

Protrudin regulates endoplasmic reticulum morphology and function associated with the pathogenesis of hereditary spastic paraplegia.
Hashimoto Y, Shirane M, Matsuzaki F, Saita S, Ohnishi T, Nakayama KI
The Journal of biological chemistry289(19)12946-61(2014 May)

Arl6IP1 has the ability to shape the mammalian ER membrane in a reticulon-like fashion.
Yamamoto Y, Yoshida A, Miyazaki N, Iwasaki K, Sakisaka T
The Biochemical journal458(1)69-79(2014 Feb)

Structural basis for conformational switching and GTP loading of the large G protein atlastin.
Byrnes LJ, Singh A, Szeto K, Benvin NM, O'Donnell JP, Zipfel WR, Sondermann H
The EMBO journal32(3)369-84(2013 Feb)

Hereditary spastic paraplegia-causing mutations in atlastin-1 interfere with BMPRII trafficking.
Zhao J, Hedera P
Molecular and cellular neurosciences5287-96(2013 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

these results further supports the role of the atlastin-1 of BMP signaling cascade in axonal maintenance and axonal degeneration, which is seen in various types of hereditary spastic paraplegia.
Title: Hereditary spastic paraplegia-causing mutations in atlastin-1 interfere with BMPRII trafficking.

Data suggest that NIPA1 and atlastin-1 are members of a common biochemical pathway that supports axonal maintenance, which may explain in part the characteristic degeneration of long spinal pathways observed in patients with HSP.
Title: The effect of HSP-causing mutations in SPG3A and NIPA1 on the assembly, trafficking, and interaction between atlastin-1 and NIPA1.

SPG3A protein atlastin-1 is enriched in growth cones and promotes axon elongation during neuronal development
Title: SPG3A protein atlastin-1 is enriched in growth cones and promotes axon elongation during neuronal development.

The following Atl1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Atl1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa01280	NM_001009831.2 Latest version!	Rattus norvegicus atlastin GTPase 1 (Atl1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$307.30 $439.00
ORa29381	XM_017594227.1 Latest version!	Rattus norvegicus atlastin GTPase 1 (Atl1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00

ORF Online Only Promotion

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2-4 Clone	40% OFF
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Atl1 ( NM_001009831.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001009831.1 Rattus norvegicus atlastin GTPase 1 (Atl1), mRNA.

Price & Availability↑

CloneID	ORa01280
Clone ID Related Accession (Same CDS sequence)	NM_001009831.2
Accession Version	NM_001009831.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1677bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-16
Organism	Rattus norvegicus(Norway rat)
Product	atlastin-1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AY581896.2. On Feb 8, 2005 this sequence version replaced NM_001009831.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY581896.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGGCTAAGA GCCGCAGGGA CAGAAACAGT TGGGGTGGGT TTTCAGAGAA GTCAAGTGAT 
TGGAGCTCAG AAGAGGAGGA GCCGGTGAGA AAGGCAGGAC CCGTCCAAGT CCTCATCGTC 
AAAGACGACC ATTCCTTTGA GTTAGATGAG GCTGCACTGA ACCGGATCCT TCTGTCTGAG 
GCCGTCAGAG ACAAGGAAGT GGTTGCCGTG TCTGTTGCTG GAGCCTTTAG AAAAGGAAAA 
TCCTTCCTGA TGGACTTCAT GTTACGGTAC ATGTACAACC AGGAATCTGT TGATTGGGTT 
GGAGATTACA ATGAACCATT GACTGGATTT TCATGGAGAG GTGGATCTGA ACGAGAAACC 
ACAGGAATCC AGATCTGGAG CGAAGTTTTC CTCATCAATA AGCTTGATGG TAAAAAGGTT 
GCAGTGTTAC TGATGGATAC TCAGGGAACC TTTGACAGTC AGTCAACTTT GAGAGATTCG 
GCCACAGTAT TTGCCCTTAG CACAATGATA AGCTCAATAC AGGTCTACAA CTTATCCCAA 
AATGTCCAGG AGGACGACCT TCAGCATCTC CAGCTTTTCA CTGAGTATGG CAGGTTGGCA 
ATGGAAGAAA CATTCCTGAA GCCTTTTCAG AGTCTGATAT TTCTTGTTCG AGACTGGAGT 
TTCCCATACG AATTCTCATA CGGAGCTGAT GGTGGCGCCA AGTTTTTGGA AAAACGCCTC 
AAGGTCTCAG GGAACCAGCA CGAAGAACTA CAGAATGTCA GAAAGCACAT CCATTCCTGT 
TTTACCAACA TTTCCTGTTT TCTCCTACCT CATCCTGGCT TAAAAGTAGC TACGAACCCA 
AACTTTGATG GAAAACTAAA AGAAATAGAT GACGAATTCA TCAAAAACTT GAAAATACTG 
ATTCCGTGGC TCCTTAGTCC CGAGAGCCTA GATATTAAAG AGATCAATGG GAATAAAATC 
ACCTGCCGAG GTCTGCTGGA GTACTTCAAG GCGTACATAA AGATCTACCA AGGGGAAGAA 
TTGCCACATC CCAAGTCCAT GTTACAGGCC ACAGCAGAAG CCAACAACCT AGCAGCTGTT 
GCAACCGCCA AGGACACATA CAACAAGAAG ATGGAGGAGA TTTGTGGTGG TGACAAACCA 
TTCTTGGCCC CCAATGACCT GCAAACCAAG CACCTGCAGC TAAAAGAAGA CTCTGTGAAG 
CTGTTCCGAG GTGTGAAGAA GATGGGTGGG GAAGAATTCA GCCGGCGCTA CCTACAGCAG 
CTGGAGAGTG AAATAGACGA ACTCTACATC CAGTACATCA AGCACAATGA CAGCAAAAAT 
ATCTTCCATG CCGCTCGCAC CCCAGCCACA CTGTTTGTTG TCATCTTTAT CACGTATGTC 
ATCGCTGGTG TGACTGGATT CATTGGTTTG GACATCATAG CTAGCCTGTG CAACATGATC 
ATGGGACTGA CACTCATCAC GCTGTGCACC TGGGCATACA TCCGCTACTC TGGGGAGTAT 
CGAGAGCTGG GCGCTGTAAT CGACCAGGTA GCTGCAGCTT TGTGGGACCA GGGAAGCACA 
AATGAGGCTT TATACAAGCT GTACAGTGCA GCAGCAACCC ACAGACACCT GTATCAGCAA 
GCCTTTCCTG CACCCAAGTC AGAACCTACT GAGCAACCGG AAAAGAAGAA AATTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001009831.1
CDS	219..1895
Translation	MAKSRRDRNSWGGFSEKSSDWSSEEEEPVRKAGPVQVLIVKDDHSFELDEAALNRILLSEAVRDKEVVAVSVAGAFRKGKSFLMDFMLRYMYNQESVDWVGDYNEPLTGFSWRGGSERETTGIQIWSEVFLINKLDGKKVAVLLMDTQGTFDSQSTLRDSATVFALSTMISSIQVYNLSQNVQEDDLQHLQLFTEYGRLAMEETFLKPFQSLIFLVRDWSFPYEFSYGADGGAKFLEKRLKVSGNQHEELQNVRKHIHSCFTNISCFLLPHPGLKVATNPNFDGKLKEIDDEFIKNLKILIPWLLSPESLDIKEINGNKITCRGLLEYFKAYIKIYQGEELPHPKSMLQATAEANNLAAVATAKDTYNKKMEEICGGDKPFLAPNDLQTKHLQLKEDSVKLFRGVKKMGGEEFSRRYLQQLESEIDELYIQYIKHNDSKNIFHAARTPATLFVVIFITYVIAGVTGFIGLDIIASLCNMIMGLTLITLCTWAYIRYSGEYRELGAVIDQVAAALWDQGSTNEALYKLYSAAATHRHLYQQAFPAPKSEPTEQPEKKKI

Target ORF information:

RefSeq Version	NM_001009831.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus atlastin GTPase 1 (Atl1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001009831.2

ORF Insert Sequence:

ATGGCTAAGA GCCGCAGGGA CAGAAACAGT TGGGGTGGGT TTTCAGAGAA GTCAAGTGAT 
TGGAGCTCAG AAGAGGAGGA GCCGGTGAGA AAGGCAGGAC CCGTCCAAGT CCTCATCGTC 
AAAGACGACC ATTCCTTTGA GTTAGATGAG GCTGCACTGA ACCGGATCCT TCTGTCTGAG 
GCCGTCAGAG ACAAGGAAGT GGTTGCCGTG TCTGTTGCTG GAGCCTTTAG AAAAGGAAAA 
TCCTTCCTGA TGGACTTCAT GTTACGGTAC ATGTACAACC AGGAATCTGT TGATTGGGTT 
GGAGATTACA ATGAACCATT GACTGGATTT TCATGGAGAG GTGGATCTGA ACGAGAAACC 
ACAGGAATCC AGATCTGGAG CGAAGTTTTC CTCATCAATA AGCTTGATGG TAAAAAGGTT 
GCAGTGTTAC TGATGGATAC TCAGGGAACC TTTGACAGTC AGTCAACTTT GAGAGATTCG 
GCCACAGTAT TTGCCCTTAG CACAATGATA AGCTCAATAC AGGTCTACAA CTTATCCCAA 
AATGTCCAGG AGGACGACCT TCAGCATCTC CAGCTTTTCA CTGAGTATGG CAGGTTGGCA 
ATGGAAGAAA CATTCCTGAA GCCTTTTCAG AGTCTGATAT TTCTTGTTCG AGACTGGAGT 
TTCCCATACG AATTCTCATA CGGAGCTGAT GGTGGCGCCA AGTTTTTGGA AAAACGCCTC 
AAGGTCTCAG GGAACCAGCA CGAAGAACTA CAGAATGTCA GAAAGCACAT CCATTCCTGT 
TTTACCAACA TTTCCTGTTT TCTCCTACCT CATCCTGGCT TAAAAGTAGC TACGAACCCA 
AACTTTGATG GAAAACTAAA AGAAATAGAT GACGAATTCA TCAAAAACTT GAAAATACTG 
ATTCCGTGGC TCCTTAGTCC CGAGAGCCTA GATATTAAAG AGATCAATGG GAATAAAATC 
ACCTGCCGAG GTCTGCTGGA GTACTTCAAG GCGTACATAA AGATCTACCA AGGGGAAGAA 
TTGCCACATC CCAAGTCCAT GTTACAGGCC ACAGCAGAAG CCAACAACCT AGCAGCTGTT 
GCAACCGCCA AGGACACATA CAACAAGAAG ATGGAGGAGA TTTGTGGTGG TGACAAACCA 
TTCTTGGCCC CCAATGACCT GCAAACCAAG CACCTGCAGC TAAAAGAAGA CTCTGTGAAG 
CTGTTCCGAG GTGTGAAGAA GATGGGTGGG GAAGAATTCA GCCGGCGCTA CCTACAGCAG 
CTGGAGAGTG AAATAGACGA ACTCTACATC CAGTACATCA AGCACAATGA CAGCAAAAAT 
ATCTTCCATG CCGCTCGCAC CCCAGCCACA CTGTTTGTTG TCATCTTTAT CACGTATGTC 
ATCGCTGGTG TGACTGGATT CATTGGTTTG GACATCATAG CTAGCCTGTG CAACATGATC 
ATGGGACTGA CACTCATCAC GCTGTGCACC TGGGCATACA TCCGCTACTC TGGGGAGTAT 
CGAGAGCTGG GCGCTGTAAT CGACCAGGTA GCTGCAGCTT TGTGGGACCA GGGAAGCACA 
AATGAGGCTT TATACAAGCT GTACAGTGCA GCAGCAACCC ACAGACACCT GTATCAGCAA 
GCCTTTCCTG CACCCAAGTC AGAACCTACT GAGCAACCGG AAAAGAAGAA AATTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Atl1 ( XM_017594227.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017449716.1 Rattus norvegicus atlastin GTPase 1 (Atl1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa29381
Clone ID Related Accession (Same CDS sequence)	XM_017594227.1
Accession Version	XM_017594227.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1662bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	atlastin-1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005105.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTAAGA GCCGCAGGGA CAGAAACAGT TGGGGTGGGT TTTCAGAGAA GTCAAGTGAT 
TGGAGCTCAG AAGAGGAGGA GCCGGTGAGA AAGGCAGGAC CCGTCCAAGT CCTCATCGTC 
AAAGACGACC ATTCCTTTGA GTTAGATGAG GCTGCACTGA ACCGGATCCT TCTGTCTGAG 
GCCGTCAGAG ACAAGGAAGT GGTTGCCGTG TCTGTTGCTG GAGCCTTTAG AAAAGGAAAA 
TCCTTCCTGA TGGACTTCAT GTTACGGTAC ATGTACAACC AGGAATCTGT TGATTGGGTT 
GGAGATTACA ATGAACCATT GACTGGATTT TCATGGAGAG GTGGATCTGA ACGAGAAACC 
ACAGGAATCC AGATCTGGAG CGAAGTTTTC CTCATCAATA AGCTTGATGG TAAAAAGGTT 
GCAGTGTTAC TGATGGATAC TCAGGGAACC TTTGACAGTC AGTCAACTTT GAGAGATTCG 
GCCACAGTAT TTGCCCTTAG CACAATGATA AGCTCAATAC AGGTCTACAA CTTATCCCAA 
AATGTCCAGG AGGACGACCT TCAGCATCTC CAGCTTTTCA CTGAGTATGG CAGGTTGGCA 
ATGGAAGAAA CATTCCTGAA GCCTTTTCAG AGTCTGATAT TTCTTGTTCG AGACTGGAGT 
TTCCCATACG AATTCTCATA CGGAGCTGAT GGTGGCGCCA AGTTTTTGGA AAAACGCCTC 
AAGGTCTCAG GGAACCAGCA CGAAGAACTA CAGAATGTCA GAAAGCACAT CCATTCCTGT 
TTTACCAACA TTTCCTGTTT TCTCCTACCT CATCCTGGCT TAAAAGTAGC TACGAACCCA 
AACTTTGATG GAAAACTAAA AGAAATAGAT GACGAATTCA TCAAAAACTT GAAAATACTG 
ATTCCGTGGC TCCTTAGTCC CGAGAGCCTA GATATTAAAG AGATCAATGG GAATAAAATC 
ACCTGCCGAG GTCTGCTGGA GTACTTCAAG GCGTACATAA AGATCTACCA AGGGGAAGAA 
TTGCCACATC CCAAGTCCAT GTTACAGGCC ACAGCAGAAG CCAACAACCT AGCAGCTGTT 
GCAACCGCCA AGGACACATA CAACAAGAAG ATGGAGGAGA TTTGTGGTGG TGACAAACCA 
TTCTTGGCCC CCAATGACCT GCAAACCAAG CACCTGCAGC TAAAAGAAGA CTCTGTGAAG 
CTGTTCCGAG GTGTGAAGAA GATGGGTGGG GAAGAATTCA GCCGGCGCTA CCTACAGCAG 
CTGGAGAGTG AAATAGACGA ACTCTACATC CAGTACATCA AGCACAATGA CAGCAAAAAT 
ATCTTCCATG CCGCTCGCAC CCCAGCCACA CTGTTTGTTG TCATCTTTAT CACGTATGTC 
ATCGCTGGTG TGACTGGATT CATTGGTTTG GACATCATAG CTAGCCTGTG CAACATGATC 
ATGGGACTGA CACTCATCAC GCTGTGCACC TGGGCATACA TCCGCTACTC TGGGGAGTAT 
CGAGAGCTGG GCGCTGTAAT CGACCAGGTA GCTGCAGCTT TGTGGGACCA GGCTTTATAC 
AAGCTGTACA GTGCAGCAGC AACCCACAGA CACCTGTATC AGCAAGCCTT TCCTGCACCC 
AAGTCAGAAC CTACTGAGCA ACCGGAAAAG AAGAAAATTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017449716.1
CDS	240..1901
Translation	MAKSRRDRNSWGGFSEKSSDWSSEEEEPVRKAGPVQVLIVKDDHSFELDEAALNRILLSEAVRDKEVVAVSVAGAFRKGKSFLMDFMLRYMYNQESVDWVGDYNEPLTGFSWRGGSERETTGIQIWSEVFLINKLDGKKVAVLLMDTQGTFDSQSTLRDSATVFALSTMISSIQVYNLSQNVQEDDLQHLQLFTEYGRLAMEETFLKPFQSLIFLVRDWSFPYEFSYGADGGAKFLEKRLKVSGNQHEELQNVRKHIHSCFTNISCFLLPHPGLKVATNPNFDGKLKEIDDEFIKNLKILIPWLLSPESLDIKEINGNKITCRGLLEYFKAYIKIYQGEELPHPKSMLQATAEANNLAAVATAKDTYNKKMEEICGGDKPFLAPNDLQTKHLQLKEDSVKLFRGVKKMGGEEFSRRYLQQLESEIDELYIQYIKHNDSKNIFHAARTPATLFVVIFITYVIAGVTGFIGLDIIASLCNMIMGLTLITLCTWAYIRYSGEYRELGAVIDQVAAALWDQALYKLYSAAATHRHLYQQAFPAPKSEPTEQPEKKKI

Target ORF information:

RefSeq Version	XM_017594227.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus atlastin GTPase 1 (Atl1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017594227.1

ORF Insert Sequence:

ATGGCTAAGA GCCGCAGGGA CAGAAACAGT TGGGGTGGGT TTTCAGAGAA GTCAAGTGAT 
TGGAGCTCAG AAGAGGAGGA GCCGGTGAGA AAGGCAGGAC CCGTCCAAGT CCTCATCGTC 
AAAGACGACC ATTCCTTTGA GTTAGATGAG GCTGCACTGA ACCGGATCCT TCTGTCTGAG 
GCCGTCAGAG ACAAGGAAGT GGTTGCCGTG TCTGTTGCTG GAGCCTTTAG AAAAGGAAAA 
TCCTTCCTGA TGGACTTCAT GTTACGGTAC ATGTACAACC AGGAATCTGT TGATTGGGTT 
GGAGATTACA ATGAACCATT GACTGGATTT TCATGGAGAG GTGGATCTGA ACGAGAAACC 
ACAGGAATCC AGATCTGGAG CGAAGTTTTC CTCATCAATA AGCTTGATGG TAAAAAGGTT 
GCAGTGTTAC TGATGGATAC TCAGGGAACC TTTGACAGTC AGTCAACTTT GAGAGATTCG 
GCCACAGTAT TTGCCCTTAG CACAATGATA AGCTCAATAC AGGTCTACAA CTTATCCCAA 
AATGTCCAGG AGGACGACCT TCAGCATCTC CAGCTTTTCA CTGAGTATGG CAGGTTGGCA 
ATGGAAGAAA CATTCCTGAA GCCTTTTCAG AGTCTGATAT TTCTTGTTCG AGACTGGAGT 
TTCCCATACG AATTCTCATA CGGAGCTGAT GGTGGCGCCA AGTTTTTGGA AAAACGCCTC 
AAGGTCTCAG GGAACCAGCA CGAAGAACTA CAGAATGTCA GAAAGCACAT CCATTCCTGT 
TTTACCAACA TTTCCTGTTT TCTCCTACCT CATCCTGGCT TAAAAGTAGC TACGAACCCA 
AACTTTGATG GAAAACTAAA AGAAATAGAT GACGAATTCA TCAAAAACTT GAAAATACTG 
ATTCCGTGGC TCCTTAGTCC CGAGAGCCTA GATATTAAAG AGATCAATGG GAATAAAATC 
ACCTGCCGAG GTCTGCTGGA GTACTTCAAG GCGTACATAA AGATCTACCA AGGGGAAGAA 
TTGCCACATC CCAAGTCCAT GTTACAGGCC ACAGCAGAAG CCAACAACCT AGCAGCTGTT 
GCAACCGCCA AGGACACATA CAACAAGAAG ATGGAGGAGA TTTGTGGTGG TGACAAACCA 
TTCTTGGCCC CCAATGACCT GCAAACCAAG CACCTGCAGC TAAAAGAAGA CTCTGTGAAG 
CTGTTCCGAG GTGTGAAGAA GATGGGTGGG GAAGAATTCA GCCGGCGCTA CCTACAGCAG 
CTGGAGAGTG AAATAGACGA ACTCTACATC CAGTACATCA AGCACAATGA CAGCAAAAAT 
ATCTTCCATG CCGCTCGCAC CCCAGCCACA CTGTTTGTTG TCATCTTTAT CACGTATGTC 
ATCGCTGGTG TGACTGGATT CATTGGTTTG GACATCATAG CTAGCCTGTG CAACATGATC 
ATGGGACTGA CACTCATCAC GCTGTGCACC TGGGCATACA TCCGCTACTC TGGGGAGTAT 
CGAGAGCTGG GCGCTGTAAT CGACCAGGTA GCTGCAGCTT TGTGGGACCA GGCTTTATAC 
AAGCTGTACA GTGCAGCAGC AACCCACAGA CACCTGTATC AGCAAGCCTT TCCTGCACCC 
AAGTCAGAAC CTACTGAGCA ACCGGAAAAG AAGAAAATTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Cooperation of the ER-shaping proteins atlastin, lunapark, and reticulons to generate a tubular membrane network.
eLife5(2016 09)
Wang S,Tukachinsky H,Romano FB,Rapoport TA

Protrudin regulates endoplasmic reticulum morphology and function associated with the pathogenesis of hereditary spastic paraplegia.
The Journal of biological chemistry289(19)12946-61(2014 May)
Hashimoto Y,Shirane M,Matsuzaki F,Saita S,Ohnishi T,Nakayama KI

Arl6IP1 has the ability to shape the mammalian ER membrane in a reticulon-like fashion.
The Biochemical journal458(1)69-79(2014 Feb)
Yamamoto Y,Yoshida A,Miyazaki N,Iwasaki K,Sakisaka T

Structural basis for conformational switching and GTP loading of the large G protein atlastin.
The EMBO journal32(3)369-84(2013 Feb)
Byrnes LJ,Singh A,Szeto K,Benvin NM,O'Donnell JP,Zipfel WR,Sondermann H

Hereditary spastic paraplegia-causing mutations in atlastin-1 interfere with BMPRII trafficking.
Molecular and cellular neurosciences5287-96(2013 Jan)
Zhao J,Hedera P

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Atl1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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