ATL1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	ATL1
Entrez Gene ID	51062
Full Name	atlastin GTPase 1
Synonyms	AD-FSP,FSP1,GBP3,HSN1D,SPG3,SPG3A,atlastin1
General protein information	Preferred Names atlastin GTPase 1 Names atlastin-1 GBP-3 GTP-binding protein 3 brain-specific GTP-binding protein guanine nucleotide-binding protein 3 guanylate-binding protein 3 hGBP3 spastic paraplegia 3 protein A
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 14 Map Location: 14q22.1
Summary	The protein encoded by this gene is a GTPase and a Golgi body transmembrane protein. The encoded protein can form a homotetramer and has been shown to interact with spastin and with mitogen-activated protein kinase kinase kinase kinase 4. This protein may be involved in axonal maintenance as evidenced by the fact that defects in this gene are a cause of spastic paraplegia type 3. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
Disorder MIM:	606439
Disorder Html:	Spastic paraplegia 3A, autosomal dominant, 182600 (3); Neuropathy, hereditary sensory, type ID, 613708 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_015915.5	NP_056999.2	atlastin-1 isoform a
NM_015915.4	NP_056999.2	atlastin-1 isoform a
NM_001127713.1	NP_001121185.1	atlastin-1 isoform b
NM_181598.3	NP_853629.2	atlastin-1 isoform b

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	ATL1	XP_005623439.1
	ATL1	XP_001101240.1
Gallus gallus (chicken)	ATL1	XP_421466.4
Pan troglodytes (chimpanzee)	ATL1	XP_001156076.1
Mus musculus (house mouse)	Atl1	NP_848743.1
Danio rerio (zebrafish)	atl1	NP_001139172.1
Xenopus tropicalis (tropical clawed frog)	atl1	NP_001072222.1
Homo sapiens (human)	ATL1	NP_056999.2
Bos taurus (cattle)	ATL1	NP_001029803.1
Rattus norvegicus (Norway rat)	Atl1	NP_001009831.1

Gene Ontology
Bibliography

Related articles in PubMed

Disease-Causing Variants in the ATL1 Gene Are a Rare Cause of Hereditary Spastic Paraplegia among Czech Patients.
M?sz?rosov? AU, Gre?malov? D, Br?zdilov? M, Dvo???kov? N, Kalina Z, ?erm?kov? M, V?vrov? D, Smetanov? I, Stan?k D, Seeman P
Annals of human genetics81(6)249-257(2017 Nov)

The crossover conformational shift of the GTPase atlastin provides the energy driving ER fusion.
Winsor J, Hackney DD, Lee TH
The Journal of cell biology216(5)1321-1335(2017 May)

Atlastin regulates store-operated calcium entry for nerve growth factor-induced neurite outgrowth.
Li J, Yan B, Si H, Peng X, Zhang SL, Hu J
Scientific reports743490(2017 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The results suggest that tethering and lipid mixing are catalyzed concurrently by atlastin GTPase hydrolysis but that the energy requirement for lipid mixing exceeds that for tethering, and the full energy released through crossover formation is necessary for fusion.
Title: The crossover conformational shift of the GTPase atlastin provides the energy driving ER fusion.

that Atlastin 1 mutations may cause autosomal recessively inherited paraplegia with an underlying loss-of-function mechanism. Hence, patients with recessive forms of HSP should also be tested for the Atlastin 1 gene.
Title: Homozygous mutation in Atlastin GTPase 1 causes recessive hereditary spastic paraplegia.

This study showed that the mutations of were detected in SPG11, ATL1, NIPA1, and ABCD1 in patient with hereditary spastic paraplegia.
Title: Genetic background of the hereditary spastic paraplegia phenotypes in Hungary - An analysis of 58 probands.

We identified two novel mutations and two previously reported mutations in SPAST and ATL1, respectively. The family with the ATL1 c.1204T>G mutation exhibited male-lethality, female infancy-onset, and pseudo- X-linked dominant transmission
Title: Mutation analysis of four Chinese families with pure hereditary spastic paraplegia: pseudo- X-linked dominant inheritance and male lethality due to a novel ATL1 mutation.

Novel splicing pathogenic variants were identified in ATL1 genes of Korean patients with hereditary spastic paraplegia.
Title: Mutational spectrum of the SPAST and ATL1 genes in Korean patients with hereditary spastic paraplegia.

The following ATL1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ATL1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu16393	NM_181598.3 Latest version!	Homo sapiens atlastin GTPase 1 (ATL1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$321.30 $459.00
OHu16393	NM_001127713.1 Latest version!	Homo sapiens atlastin GTPase 1 (ATL1), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$321.30 $459.00
OHu18832	NM_015915.5 Latest version!	Homo sapiens atlastin GTPase 1 (ATL1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
View Old Accession Versions >>
OHu18832	NM_015915.4	Homo sapiens atlastin GTPase 1 (ATL1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$265.30 $379.00
Hide Old Accession Versions >>

ORF Online Only Promotion

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ATL1 ( NM_001127713.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001121185.1 Homo sapiens atlastin GTPase 1 (ATL1), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu16393
Clone ID Related Accession (Same CDS sequence)	NM_001127713.1 , NM_181598.3
Accession Version	NM_001127713.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1662bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-30
Organism	Homo sapiens(human)
Product	atlastin-1 isoform b
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA397302.1, AL833591.1, AK290185.1, AK223436.1 and R61338.1. This sequence is a reference standard in the RefSeqGene project. Transcript Variant: This variant (3) lacks an alternate in-frame exon and differs in the 5' UTR compared to variant 1. The resulting isoform (b) has the same N- and C-termini but is shorter compared to isoform a. Variants 2 and 3 both encode isoform b. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660805.184614.1, AL833591.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCAAGA ACCGCAGGGA CAGAAACAGT TGGGGTGGAT TTTCGGAAAA GACATATGAA 
TGGAGCTCAG AAGAGGAGGA GCCAGTGAAA AAGGCAGGAC CAGTCCAAGT CCTCATTGTC 
AAAGATGACC ATTCCTTTGA GTTAGATGAA ACTGCATTAA ATCGGATCCT TCTCTCGGAG 
GCTGTCAGAG ACAAGGAGGT TGTTGCTGTA TCTGTTGCTG GAGCATTTAG AAAAGGAAAA 
TCATTCCTGA TGGACTTCAT GTTGAGATAC ATGTACAACC AGGAATCAGT TGATTGGGTT 
GGAGACTACA ATGAACCATT GACTGGTTTT TCATGGAGAG GTGGATCTGA GCGAGAGACC 
ACAGGAATTC AGATATGGAG TGAAATCTTC CTTATCAATA AACCTGATGG TAAAAAGGTT 
GCAGTGTTAT TGATGGATAC TCAGGGAACC TTTGATAGTC AGTCAACTTT GAGAGATTCA 
GCCACAGTAT TTGCCCTTAG CACAATGATC AGCTCAATAC AGGTATATAA CTTATCCCAA 
AATGTCCAGG AGGATGATCT TCAGCACCTC CAGCTTTTCA CTGAGTATGG CAGACTGGCA 
ATGGAGGAAA CATTCCTGAA GCCATTTCAG AGTCTGATAT TTCTTGTTCG AGACTGGAGT 
TTCCCATACG AATTTTCATA TGGAGCCGAT GGTGGTGCCA AATTCTTGGA AAAACGCCTC 
AAGGTCTCAG GGAACCAGCA TGAAGAACTA CAGAACGTCA GAAAACACAT CCATTCCTGT 
TTCACCAACA TTTCCTGTTT TCTGCTACCT CATCCTGGCT TAAAAGTAGC TACCAATCCA 
AACTTTGATG GAAAATTGAA AGAAATAGAT GATGAATTCA TCAAAAACTT GAAAATACTG 
ATTCCTTGGC TACTTAGTCC CGAGAGCCTA GATATTAAAG AGATCAATGG GAATAAAATC 
ACCTGCCGGG GTCTGGTGGA GTACTTCAAG GCTTATATAA AGATCTATCA AGGTGAAGAA 
TTACCACATC CCAAATCCAT GTTACAGGCC ACAGCAGAAG CTAACAATTT AGCAGCCGTG 
GCAACTGCCA AGGACACATA CAACAAAAAA ATGGAAGAGA TTTGTGGTGG TGACAAACCA 
TTTCTGGCCC CAAATGACTT GCAGACCAAA CACCTGCAAC TTAAGGAAGA ATCTGTGAAG 
CTATTCCGAG GGGTGAAGAA GATGGGTGGG GAAGAATTTA GCCGGCGTTA CCTGCAGCAG 
TTGGAGAGTG AAATAGATGA ACTTTACATC CAATATATCA AGCACAATGA TAGCAAAAAT 
ATCTTCCATG CAGCTCGTAC CCCAGCCACA CTGTTTGTAG TCATCTTTAT CACATATGTG 
ATTGCTGGTG TGACTGGATT CATTGGTTTG GACATCATAG CTAGCCTATG CAATATGATA 
ATGGGACTGA CCCTTATCAC CCTGTGCACT TGGGCATATA TCCGGTACTC TGGAGAATAC 
CGAGAGCTGG GAGCTGTAAT AGACCAGGTG GCTGCAGCTC TGTGGGACCA GGCTTTGTAC 
AAGCTTTACA GTGCAGCAGC AACCCACAGA CATCTGTATC ATCAAGCTTT CCCTACACCA 
AAGTCGGAAT CTACTGAACA ATCAGAAAAG AAAAAAATGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001121185.1
CDS	426..2087
Translation	MAKNRRDRNSWGGFSEKTYEWSSEEEEPVKKAGPVQVLIVKDDHSFELDETALNRILLSEAVRDKEVVAVSVAGAFRKGKSFLMDFMLRYMYNQESVDWVGDYNEPLTGFSWRGGSERETTGIQIWSEIFLINKPDGKKVAVLLMDTQGTFDSQSTLRDSATVFALSTMISSIQVYNLSQNVQEDDLQHLQLFTEYGRLAMEETFLKPFQSLIFLVRDWSFPYEFSYGADGGAKFLEKRLKVSGNQHEELQNVRKHIHSCFTNISCFLLPHPGLKVATNPNFDGKLKEIDDEFIKNLKILIPWLLSPESLDIKEINGNKITCRGLVEYFKAYIKIYQGEELPHPKSMLQATAEANNLAAVATAKDTYNKKMEEICGGDKPFLAPNDLQTKHLQLKEESVKLFRGVKKMGGEEFSRRYLQQLESEIDELYIQYIKHNDSKNIFHAARTPATLFVVIFITYVIAGVTGFIGLDIIASLCNMIMGLTLITLCTWAYIRYSGEYRELGAVIDQVAAALWDQALYKLYSAAATHRHLYHQAFPTPKSESTEQSEKKKM

Target ORF information:

RefSeq Version	NM_001127713.1
Organism	Homo sapiens(human)
Definition	Homo sapiens atlastin GTPase 1 (ATL1), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001127713.1

ORF Insert Sequence:

ATGGCCAAGA ACCGCAGGGA CAGAAACAGT TGGGGTGGAT TTTCGGAAAA GACATATGAA 
TGGAGCTCAG AAGAGGAGGA GCCAGTGAAA AAGGCAGGAC CAGTCCAAGT CCTCATTGTC 
AAAGATGACC ATTCCTTTGA GTTAGATGAA ACTGCATTAA ATCGGATCCT TCTCTCGGAG 
GCTGTCAGAG ACAAGGAGGT TGTTGCTGTA TCTGTTGCTG GAGCATTTAG AAAAGGAAAA 
TCATTCCTGA TGGACTTCAT GTTGAGATAC ATGTACAACC AGGAATCAGT TGATTGGGTT 
GGAGACTACA ATGAACCATT GACTGGTTTT TCATGGAGAG GTGGATCTGA GCGAGAGACC 
ACAGGAATTC AGATATGGAG TGAAATCTTC CTTATCAATA AACCTGATGG TAAAAAGGTT 
GCAGTGTTAT TGATGGATAC TCAGGGAACC TTTGATAGTC AGTCAACTTT GAGAGATTCA 
GCCACAGTAT TTGCCCTTAG CACAATGATC AGCTCAATAC AGGTATATAA CTTATCCCAA 
AATGTCCAGG AGGATGATCT TCAGCACCTC CAGCTTTTCA CTGAGTATGG CAGACTGGCA 
ATGGAGGAAA CATTCCTGAA GCCATTTCAG AGTCTGATAT TTCTTGTTCG AGACTGGAGT 
TTCCCATACG AATTTTCATA TGGAGCCGAT GGTGGTGCCA AATTCTTGGA AAAACGCCTC 
AAGGTCTCAG GGAACCAGCA TGAAGAACTA CAGAACGTCA GAAAACACAT CCATTCCTGT 
TTCACCAACA TTTCCTGTTT TCTGCTACCT CATCCTGGCT TAAAAGTAGC TACCAATCCA 
AACTTTGATG GAAAATTGAA AGAAATAGAT GATGAATTCA TCAAAAACTT GAAAATACTG 
ATTCCTTGGC TACTTAGTCC CGAGAGCCTA GATATTAAAG AGATCAATGG GAATAAAATC 
ACCTGCCGGG GTCTGGTGGA GTACTTCAAG GCTTATATAA AGATCTATCA AGGTGAAGAA 
TTACCACATC CCAAATCCAT GTTACAGGCC ACAGCAGAAG CTAACAATTT AGCAGCCGTG 
GCAACTGCCA AGGACACATA CAACAAAAAA ATGGAAGAGA TTTGTGGTGG TGACAAACCA 
TTTCTGGCCC CAAATGACTT GCAGACCAAA CACCTGCAAC TTAAGGAAGA ATCTGTGAAG 
CTATTCCGAG GGGTGAAGAA GATGGGTGGG GAAGAATTTA GCCGGCGTTA CCTGCAGCAG 
TTGGAGAGTG AAATAGATGA ACTTTACATC CAATATATCA AGCACAATGA TAGCAAAAAT 
ATCTTCCATG CAGCTCGTAC CCCAGCCACA CTGTTTGTAG TCATCTTTAT CACATATGTG 
ATTGCTGGTG TGACTGGATT CATTGGTTTG GACATCATAG CTAGCCTATG CAATATGATA 
ATGGGACTGA CCCTTATCAC CCTGTGCACT TGGGCATATA TCCGGTACTC TGGAGAATAC 
CGAGAGCTGG GAGCTGTAAT AGACCAGGTG GCTGCAGCTC TGTGGGACCA GGCTTTGTAC 
AAGCTTTACA GTGCAGCAGC AACCCACAGA CATCTGTATC ATCAAGCTTT CCCTACACCA 
AAGTCGGAAT CTACTGAACA ATCAGAAAAG AAAAAAATGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ATL1 ( NM_181598.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_853629.2 Homo sapiens atlastin GTPase 1 (ATL1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu16393
Clone ID Related Accession (Same CDS sequence)	NM_001127713.1 , NM_181598.3
Accession Version	NM_181598.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1662bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-30
Organism	Homo sapiens(human)
Product	atlastin-1 isoform b
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA088230.1, AL833591.1, AK290185.1, AK223436.1 and R61338.1. On May 30, 2008 this sequence version replaced NM_181598.2. Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (b) has the same N- and C-termini but is shorter compared to isoform a. Variants 2 and 3 both encode isoform b. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660807.165740.1, SRR1660805.3437.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCAAGA ACCGCAGGGA CAGAAACAGT TGGGGTGGAT TTTCGGAAAA GACATATGAA 
TGGAGCTCAG AAGAGGAGGA GCCAGTGAAA AAGGCAGGAC CAGTCCAAGT CCTCATTGTC 
AAAGATGACC ATTCCTTTGA GTTAGATGAA ACTGCATTAA ATCGGATCCT TCTCTCGGAG 
GCTGTCAGAG ACAAGGAGGT TGTTGCTGTA TCTGTTGCTG GAGCATTTAG AAAAGGAAAA 
TCATTCCTGA TGGACTTCAT GTTGAGATAC ATGTACAACC AGGAATCAGT TGATTGGGTT 
GGAGACTACA ATGAACCATT GACTGGTTTT TCATGGAGAG GTGGATCTGA GCGAGAGACC 
ACAGGAATTC AGATATGGAG TGAAATCTTC CTTATCAATA AACCTGATGG TAAAAAGGTT 
GCAGTGTTAT TGATGGATAC TCAGGGAACC TTTGATAGTC AGTCAACTTT GAGAGATTCA 
GCCACAGTAT TTGCCCTTAG CACAATGATC AGCTCAATAC AGGTATATAA CTTATCCCAA 
AATGTCCAGG AGGATGATCT TCAGCACCTC CAGCTTTTCA CTGAGTATGG CAGACTGGCA 
ATGGAGGAAA CATTCCTGAA GCCATTTCAG AGTCTGATAT TTCTTGTTCG AGACTGGAGT 
TTCCCATACG AATTTTCATA TGGAGCCGAT GGTGGTGCCA AATTCTTGGA AAAACGCCTC 
AAGGTCTCAG GGAACCAGCA TGAAGAACTA CAGAACGTCA GAAAACACAT CCATTCCTGT 
TTCACCAACA TTTCCTGTTT TCTGCTACCT CATCCTGGCT TAAAAGTAGC TACCAATCCA 
AACTTTGATG GAAAATTGAA AGAAATAGAT GATGAATTCA TCAAAAACTT GAAAATACTG 
ATTCCTTGGC TACTTAGTCC CGAGAGCCTA GATATTAAAG AGATCAATGG GAATAAAATC 
ACCTGCCGGG GTCTGGTGGA GTACTTCAAG GCTTATATAA AGATCTATCA AGGTGAAGAA 
TTACCACATC CCAAATCCAT GTTACAGGCC ACAGCAGAAG CTAACAATTT AGCAGCCGTG 
GCAACTGCCA AGGACACATA CAACAAAAAA ATGGAAGAGA TTTGTGGTGG TGACAAACCA 
TTTCTGGCCC CAAATGACTT GCAGACCAAA CACCTGCAAC TTAAGGAAGA ATCTGTGAAG 
CTATTCCGAG GGGTGAAGAA GATGGGTGGG GAAGAATTTA GCCGGCGTTA CCTGCAGCAG 
TTGGAGAGTG AAATAGATGA ACTTTACATC CAATATATCA AGCACAATGA TAGCAAAAAT 
ATCTTCCATG CAGCTCGTAC CCCAGCCACA CTGTTTGTAG TCATCTTTAT CACATATGTG 
ATTGCTGGTG TGACTGGATT CATTGGTTTG GACATCATAG CTAGCCTATG CAATATGATA 
ATGGGACTGA CCCTTATCAC CCTGTGCACT TGGGCATATA TCCGGTACTC TGGAGAATAC 
CGAGAGCTGG GAGCTGTAAT AGACCAGGTG GCTGCAGCTC TGTGGGACCA GGCTTTGTAC 
AAGCTTTACA GTGCAGCAGC AACCCACAGA CATCTGTATC ATCAAGCTTT CCCTACACCA 
AAGTCGGAAT CTACTGAACA ATCAGAAAAG AAAAAAATGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_853629.2
CDS	242..1903
Translation	MAKNRRDRNSWGGFSEKTYEWSSEEEEPVKKAGPVQVLIVKDDHSFELDETALNRILLSEAVRDKEVVAVSVAGAFRKGKSFLMDFMLRYMYNQESVDWVGDYNEPLTGFSWRGGSERETTGIQIWSEIFLINKPDGKKVAVLLMDTQGTFDSQSTLRDSATVFALSTMISSIQVYNLSQNVQEDDLQHLQLFTEYGRLAMEETFLKPFQSLIFLVRDWSFPYEFSYGADGGAKFLEKRLKVSGNQHEELQNVRKHIHSCFTNISCFLLPHPGLKVATNPNFDGKLKEIDDEFIKNLKILIPWLLSPESLDIKEINGNKITCRGLVEYFKAYIKIYQGEELPHPKSMLQATAEANNLAAVATAKDTYNKKMEEICGGDKPFLAPNDLQTKHLQLKEESVKLFRGVKKMGGEEFSRRYLQQLESEIDELYIQYIKHNDSKNIFHAARTPATLFVVIFITYVIAGVTGFIGLDIIASLCNMIMGLTLITLCTWAYIRYSGEYRELGAVIDQVAAALWDQALYKLYSAAATHRHLYHQAFPTPKSESTEQSEKKKM

Target ORF information:

RefSeq Version	NM_181598.3
Organism	Homo sapiens(human)
Definition	Homo sapiens atlastin GTPase 1 (ATL1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_181598.3

ORF Insert Sequence:

ATGGCCAAGA ACCGCAGGGA CAGAAACAGT TGGGGTGGAT TTTCGGAAAA GACATATGAA 
TGGAGCTCAG AAGAGGAGGA GCCAGTGAAA AAGGCAGGAC CAGTCCAAGT CCTCATTGTC 
AAAGATGACC ATTCCTTTGA GTTAGATGAA ACTGCATTAA ATCGGATCCT TCTCTCGGAG 
GCTGTCAGAG ACAAGGAGGT TGTTGCTGTA TCTGTTGCTG GAGCATTTAG AAAAGGAAAA 
TCATTCCTGA TGGACTTCAT GTTGAGATAC ATGTACAACC AGGAATCAGT TGATTGGGTT 
GGAGACTACA ATGAACCATT GACTGGTTTT TCATGGAGAG GTGGATCTGA GCGAGAGACC 
ACAGGAATTC AGATATGGAG TGAAATCTTC CTTATCAATA AACCTGATGG TAAAAAGGTT 
GCAGTGTTAT TGATGGATAC TCAGGGAACC TTTGATAGTC AGTCAACTTT GAGAGATTCA 
GCCACAGTAT TTGCCCTTAG CACAATGATC AGCTCAATAC AGGTATATAA CTTATCCCAA 
AATGTCCAGG AGGATGATCT TCAGCACCTC CAGCTTTTCA CTGAGTATGG CAGACTGGCA 
ATGGAGGAAA CATTCCTGAA GCCATTTCAG AGTCTGATAT TTCTTGTTCG AGACTGGAGT 
TTCCCATACG AATTTTCATA TGGAGCCGAT GGTGGTGCCA AATTCTTGGA AAAACGCCTC 
AAGGTCTCAG GGAACCAGCA TGAAGAACTA CAGAACGTCA GAAAACACAT CCATTCCTGT 
TTCACCAACA TTTCCTGTTT TCTGCTACCT CATCCTGGCT TAAAAGTAGC TACCAATCCA 
AACTTTGATG GAAAATTGAA AGAAATAGAT GATGAATTCA TCAAAAACTT GAAAATACTG 
ATTCCTTGGC TACTTAGTCC CGAGAGCCTA GATATTAAAG AGATCAATGG GAATAAAATC 
ACCTGCCGGG GTCTGGTGGA GTACTTCAAG GCTTATATAA AGATCTATCA AGGTGAAGAA 
TTACCACATC CCAAATCCAT GTTACAGGCC ACAGCAGAAG CTAACAATTT AGCAGCCGTG 
GCAACTGCCA AGGACACATA CAACAAAAAA ATGGAAGAGA TTTGTGGTGG TGACAAACCA 
TTTCTGGCCC CAAATGACTT GCAGACCAAA CACCTGCAAC TTAAGGAAGA ATCTGTGAAG 
CTATTCCGAG GGGTGAAGAA GATGGGTGGG GAAGAATTTA GCCGGCGTTA CCTGCAGCAG 
TTGGAGAGTG AAATAGATGA ACTTTACATC CAATATATCA AGCACAATGA TAGCAAAAAT 
ATCTTCCATG CAGCTCGTAC CCCAGCCACA CTGTTTGTAG TCATCTTTAT CACATATGTG 
ATTGCTGGTG TGACTGGATT CATTGGTTTG GACATCATAG CTAGCCTATG CAATATGATA 
ATGGGACTGA CCCTTATCAC CCTGTGCACT TGGGCATATA TCCGGTACTC TGGAGAATAC 
CGAGAGCTGG GAGCTGTAAT AGACCAGGTG GCTGCAGCTC TGTGGGACCA GGCTTTGTAC 
AAGCTTTACA GTGCAGCAGC AACCCACAGA CATCTGTATC ATCAAGCTTT CCCTACACCA 
AAGTCGGAAT CTACTGAACA ATCAGAAAAG AAAAAAATGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ATL1 ( NM_015915.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_056999.2 Homo sapiens atlastin GTPase 1 (ATL1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu18832
Clone ID Related Accession (Same CDS sequence)	NM_015915.5 , NM_015915.4
Accession Version	NM_015915.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1677bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-03
Organism	Homo sapiens(human)
Product	atlastin-1 isoform a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA088230.1, AK290185.1, AK223436.1 and R61338.1. This sequence is a reference standard in the RefSeqGene project. On May 30, 2008 this sequence version replaced NM_015915.3. Transcript Variant: This variant (1) encodes the longer isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803612.22493.1, SRR1660807.253341.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCCAAGA ACCGCAGGGA CAGAAACAGT TGGGGTGGAT TTTCGGAAAA GACATATGAA 
TGGAGCTCAG AAGAGGAGGA GCCAGTGAAA AAGGCAGGAC CAGTCCAAGT CCTCATTGTC 
AAAGATGACC ATTCCTTTGA GTTAGATGAA ACTGCATTAA ATCGGATCCT TCTCTCGGAG 
GCTGTCAGAG ACAAGGAGGT TGTTGCTGTA TCTGTTGCTG GAGCATTTAG AAAAGGAAAA 
TCATTCCTGA TGGACTTCAT GTTGAGATAC ATGTACAACC AGGAATCAGT TGATTGGGTT 
GGAGACTACA ATGAACCATT GACTGGTTTT TCATGGAGAG GTGGATCTGA GCGAGAGACC 
ACAGGAATTC AGATATGGAG TGAAATCTTC CTTATCAATA AACCTGATGG TAAAAAGGTT 
GCAGTGTTAT TGATGGATAC TCAGGGAACC TTTGATAGTC AGTCAACTTT GAGAGATTCA 
GCCACAGTAT TTGCCCTTAG CACAATGATC AGCTCAATAC AGGTATATAA CTTATCCCAA 
AATGTCCAGG AGGATGATCT TCAGCACCTC CAGCTTTTCA CTGAGTATGG CAGACTGGCA 
ATGGAGGAAA CATTCCTGAA GCCATTTCAG AGTCTGATAT TTCTTGTTCG AGACTGGAGT 
TTCCCATACG AATTTTCATA TGGAGCCGAT GGTGGTGCCA AATTCTTGGA AAAACGCCTC 
AAGGTCTCAG GGAACCAGCA TGAAGAACTA CAGAACGTCA GAAAACACAT CCATTCCTGT 
TTCACCAACA TTTCCTGTTT TCTGCTACCT CATCCTGGCT TAAAAGTAGC TACCAATCCA 
AACTTTGATG GAAAATTGAA AGAAATAGAT GATGAATTCA TCAAAAACTT GAAAATACTG 
ATTCCTTGGC TACTTAGTCC CGAGAGCCTA GATATTAAAG AGATCAATGG GAATAAAATC 
ACCTGCCGGG GTCTGGTGGA GTACTTCAAG GCTTATATAA AGATCTATCA AGGTGAAGAA 
TTACCACATC CCAAATCCAT GTTACAGGCC ACAGCAGAAG CTAACAATTT AGCAGCCGTG 
GCAACTGCCA AGGACACATA CAACAAAAAA ATGGAAGAGA TTTGTGGTGG TGACAAACCA 
TTTCTGGCCC CAAATGACTT GCAGACCAAA CACCTGCAAC TTAAGGAAGA ATCTGTGAAG 
CTATTCCGAG GGGTGAAGAA GATGGGTGGG GAAGAATTTA GCCGGCGTTA CCTGCAGCAG 
TTGGAGAGTG AAATAGATGA ACTTTACATC CAATATATCA AGCACAATGA TAGCAAAAAT 
ATCTTCCATG CAGCTCGTAC CCCAGCCACA CTGTTTGTAG TCATCTTTAT CACATATGTG 
ATTGCTGGTG TGACTGGATT CATTGGTTTG GACATCATAG CTAGCCTATG CAATATGATA 
ATGGGACTGA CCCTTATCAC CCTGTGCACT TGGGCATATA TCCGGTACTC TGGAGAATAC 
CGAGAGCTGG GAGCTGTAAT AGACCAGGTG GCTGCAGCTC TGTGGGACCA GGGAAGTACA 
AATGAGGCTT TGTACAAGCT TTACAGTGCA GCAGCAACCC ACAGACATCT GTATCATCAA 
GCTTTCCCTA CACCAAAGTC GGAATCTACT GAACAATCAG AAAAGAAAAA AATGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_056999.2
CDS	242..1918
Translation	MAKNRRDRNSWGGFSEKTYEWSSEEEEPVKKAGPVQVLIVKDDHSFELDETALNRILLSEAVRDKEVVAVSVAGAFRKGKSFLMDFMLRYMYNQESVDWVGDYNEPLTGFSWRGGSERETTGIQIWSEIFLINKPDGKKVAVLLMDTQGTFDSQSTLRDSATVFALSTMISSIQVYNLSQNVQEDDLQHLQLFTEYGRLAMEETFLKPFQSLIFLVRDWSFPYEFSYGADGGAKFLEKRLKVSGNQHEELQNVRKHIHSCFTNISCFLLPHPGLKVATNPNFDGKLKEIDDEFIKNLKILIPWLLSPESLDIKEINGNKITCRGLVEYFKAYIKIYQGEELPHPKSMLQATAEANNLAAVATAKDTYNKKMEEICGGDKPFLAPNDLQTKHLQLKEESVKLFRGVKKMGGEEFSRRYLQQLESEIDELYIQYIKHNDSKNIFHAARTPATLFVVIFITYVIAGVTGFIGLDIIASLCNMIMGLTLITLCTWAYIRYSGEYRELGAVIDQVAAALWDQGSTNEALYKLYSAAATHRHLYHQAFPTPKSESTEQSEKKKM

Target ORF information:

RefSeq Version	NM_015915.4
Organism	Homo sapiens(human)
Definition	Homo sapiens atlastin GTPase 1 (ATL1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_015915.4

ORF Insert Sequence:

ATGGCCAAGA ACCGCAGGGA CAGAAACAGT TGGGGTGGAT TTTCGGAAAA GACATATGAA 
TGGAGCTCAG AAGAGGAGGA GCCAGTGAAA AAGGCAGGAC CAGTCCAAGT CCTCATTGTC 
AAAGATGACC ATTCCTTTGA GTTAGATGAA ACTGCATTAA ATCGGATCCT TCTCTCGGAG 
GCTGTCAGAG ACAAGGAGGT TGTTGCTGTA TCTGTTGCTG GAGCATTTAG AAAAGGAAAA 
TCATTCCTGA TGGACTTCAT GTTGAGATAC ATGTACAACC AGGAATCAGT TGATTGGGTT 
GGAGACTACA ATGAACCATT GACTGGTTTT TCATGGAGAG GTGGATCTGA GCGAGAGACC 
ACAGGAATTC AGATATGGAG TGAAATCTTC CTTATCAATA AACCTGATGG TAAAAAGGTT 
GCAGTGTTAT TGATGGATAC TCAGGGAACC TTTGATAGTC AGTCAACTTT GAGAGATTCA 
GCCACAGTAT TTGCCCTTAG CACAATGATC AGCTCAATAC AGGTATATAA CTTATCCCAA 
AATGTCCAGG AGGATGATCT TCAGCACCTC CAGCTTTTCA CTGAGTATGG CAGACTGGCA 
ATGGAGGAAA CATTCCTGAA GCCATTTCAG AGTCTGATAT TTCTTGTTCG AGACTGGAGT 
TTCCCATACG AATTTTCATA TGGAGCCGAT GGTGGTGCCA AATTCTTGGA AAAACGCCTC 
AAGGTCTCAG GGAACCAGCA TGAAGAACTA CAGAACGTCA GAAAACACAT CCATTCCTGT 
TTCACCAACA TTTCCTGTTT TCTGCTACCT CATCCTGGCT TAAAAGTAGC TACCAATCCA 
AACTTTGATG GAAAATTGAA AGAAATAGAT GATGAATTCA TCAAAAACTT GAAAATACTG 
ATTCCTTGGC TACTTAGTCC CGAGAGCCTA GATATTAAAG AGATCAATGG GAATAAAATC 
ACCTGCCGGG GTCTGGTGGA GTACTTCAAG GCTTATATAA AGATCTATCA AGGTGAAGAA 
TTACCACATC CCAAATCCAT GTTACAGGCC ACAGCAGAAG CTAACAATTT AGCAGCCGTG 
GCAACTGCCA AGGACACATA CAACAAAAAA ATGGAAGAGA TTTGTGGTGG TGACAAACCA 
TTTCTGGCCC CAAATGACTT GCAGACCAAA CACCTGCAAC TTAAGGAAGA ATCTGTGAAG 
CTATTCCGAG GGGTGAAGAA GATGGGTGGG GAAGAATTTA GCCGGCGTTA CCTGCAGCAG 
TTGGAGAGTG AAATAGATGA ACTTTACATC CAATATATCA AGCACAATGA TAGCAAAAAT 
ATCTTCCATG CAGCTCGTAC CCCAGCCACA CTGTTTGTAG TCATCTTTAT CACATATGTG 
ATTGCTGGTG TGACTGGATT CATTGGTTTG GACATCATAG CTAGCCTATG CAATATGATA 
ATGGGACTGA CCCTTATCAC CCTGTGCACT TGGGCATATA TCCGGTACTC TGGAGAATAC 
CGAGAGCTGG GAGCTGTAAT AGACCAGGTG GCTGCAGCTC TGTGGGACCA GGGAAGTACA 
AATGAGGCTT TGTACAAGCT TTACAGTGCA GCAGCAACCC ACAGACATCT GTATCATCAA 
GCTTTCCCTA CACCAAAGTC GGAATCTACT GAACAATCAG AAAAGAAAAA AATGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ATL1 ( NM_015915.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_056999.2 Homo sapiens atlastin GTPase 1 (ATL1), transcript variant 1, mRNA.

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CloneID	OHu18832
Clone ID Related Accession (Same CDS sequence)	NM_015915.5 , NM_015915.4
Accession Version	NM_015915.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1677bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-19
Organism	Homo sapiens(human)
Product	atlastin-1 isoform a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA088230.1, AK290185.1 and AK223436.1. On Nov 20, 2019 this sequence version replaced NM_015915.4. Transcript Variant: This variant (1) encodes the longer isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK223436.1, AK290185.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on manual assertion, conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCCAAGA ACCGCAGGGA CAGAAACAGT TGGGGTGGAT TTTCGGAAAA GACATATGAA 
TGGAGCTCAG AAGAGGAGGA GCCAGTGAAA AAGGCAGGAC CAGTCCAAGT CCTCATTGTC 
AAAGATGACC ATTCCTTTGA GTTAGATGAA ACTGCATTAA ATCGGATCCT TCTCTCGGAG 
GCTGTCAGAG ACAAGGAGGT TGTTGCTGTA TCTGTTGCTG GAGCATTTAG AAAAGGAAAA 
TCATTCCTGA TGGACTTCAT GTTGAGATAC ATGTACAACC AGGAATCAGT TGATTGGGTT 
GGAGACTACA ATGAACCATT GACTGGTTTT TCATGGAGAG GTGGATCTGA GCGAGAGACC 
ACAGGAATTC AGATATGGAG TGAAATCTTC CTTATCAATA AACCTGATGG TAAAAAGGTT 
GCAGTGTTAT TGATGGATAC TCAGGGAACC TTTGATAGTC AGTCAACTTT GAGAGATTCA 
GCCACAGTAT TTGCCCTTAG CACAATGATC AGCTCAATAC AGGTATATAA CTTATCCCAA 
AATGTCCAGG AGGATGATCT TCAGCACCTC CAGCTTTTCA CTGAGTATGG CAGACTGGCA 
ATGGAGGAAA CATTCCTGAA GCCATTTCAG AGTCTGATAT TTCTTGTTCG AGACTGGAGT 
TTCCCATACG AATTTTCATA TGGAGCCGAT GGTGGTGCCA AATTCTTGGA AAAACGCCTC 
AAGGTCTCAG GGAACCAGCA TGAAGAACTA CAGAACGTCA GAAAACACAT CCATTCCTGT 
TTCACCAACA TTTCCTGTTT TCTGCTACCT CATCCTGGCT TAAAAGTAGC TACCAATCCA 
AACTTTGATG GAAAATTGAA AGAAATAGAT GATGAATTCA TCAAAAACTT GAAAATACTG 
ATTCCTTGGC TACTTAGTCC CGAGAGCCTA GATATTAAAG AGATCAATGG GAATAAAATC 
ACCTGCCGGG GTCTGGTGGA GTACTTCAAG GCTTATATAA AGATCTATCA AGGTGAAGAA 
TTACCACATC CCAAATCCAT GTTACAGGCC ACAGCAGAAG CTAACAATTT AGCAGCCGTG 
GCAACTGCCA AGGACACATA CAACAAAAAA ATGGAAGAGA TTTGTGGTGG TGACAAACCA 
TTTCTGGCCC CAAATGACTT GCAGACCAAA CACCTGCAAC TTAAGGAAGA ATCTGTGAAG 
CTATTCCGAG GGGTGAAGAA GATGGGTGGG GAAGAATTTA GCCGGCGTTA CCTGCAGCAG 
TTGGAGAGTG AAATAGATGA ACTTTACATC CAATATATCA AGCACAATGA TAGCAAAAAT 
ATCTTCCATG CAGCTCGTAC CCCAGCCACA CTGTTTGTAG TCATCTTTAT CACATATGTG 
ATTGCTGGTG TGACTGGATT CATTGGTTTG GACATCATAG CTAGCCTATG CAATATGATA 
ATGGGACTGA CCCTTATCAC CCTGTGCACT TGGGCATATA TCCGGTACTC TGGAGAATAC 
CGAGAGCTGG GAGCTGTAAT AGACCAGGTG GCTGCAGCTC TGTGGGACCA GGGAAGTACA 
AATGAGGCTT TGTACAAGCT TTACAGTGCA GCAGCAACCC ACAGACATCT GTATCATCAA 
GCTTTCCCTA CACCAAAGTC GGAATCTACT GAACAATCAG AAAAGAAAAA AATGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_056999.2
CDS	122..1798
Translation	MAKNRRDRNSWGGFSEKTYEWSSEEEEPVKKAGPVQVLIVKDDHSFELDETALNRILLSEAVRDKEVVAVSVAGAFRKGKSFLMDFMLRYMYNQESVDWVGDYNEPLTGFSWRGGSERETTGIQIWSEIFLINKPDGKKVAVLLMDTQGTFDSQSTLRDSATVFALSTMISSIQVYNLSQNVQEDDLQHLQLFTEYGRLAMEETFLKPFQSLIFLVRDWSFPYEFSYGADGGAKFLEKRLKVSGNQHEELQNVRKHIHSCFTNISCFLLPHPGLKVATNPNFDGKLKEIDDEFIKNLKILIPWLLSPESLDIKEINGNKITCRGLVEYFKAYIKIYQGEELPHPKSMLQATAEANNLAAVATAKDTYNKKMEEICGGDKPFLAPNDLQTKHLQLKEESVKLFRGVKKMGGEEFSRRYLQQLESEIDELYIQYIKHNDSKNIFHAARTPATLFVVIFITYVIAGVTGFIGLDIIASLCNMIMGLTLITLCTWAYIRYSGEYRELGAVIDQVAAALWDQGSTNEALYKLYSAAATHRHLYHQAFPTPKSESTEQSEKKKM

Target ORF information:

RefSeq Version	NM_015915.5
Organism	Homo sapiens(human)
Definition	Homo sapiens atlastin GTPase 1 (ATL1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_015915.5

ORF Insert Sequence:

ATGGCCAAGA ACCGCAGGGA CAGAAACAGT TGGGGTGGAT TTTCGGAAAA GACATATGAA 
TGGAGCTCAG AAGAGGAGGA GCCAGTGAAA AAGGCAGGAC CAGTCCAAGT CCTCATTGTC 
AAAGATGACC ATTCCTTTGA GTTAGATGAA ACTGCATTAA ATCGGATCCT TCTCTCGGAG 
GCTGTCAGAG ACAAGGAGGT TGTTGCTGTA TCTGTTGCTG GAGCATTTAG AAAAGGAAAA 
TCATTCCTGA TGGACTTCAT GTTGAGATAC ATGTACAACC AGGAATCAGT TGATTGGGTT 
GGAGACTACA ATGAACCATT GACTGGTTTT TCATGGAGAG GTGGATCTGA GCGAGAGACC 
ACAGGAATTC AGATATGGAG TGAAATCTTC CTTATCAATA AACCTGATGG TAAAAAGGTT 
GCAGTGTTAT TGATGGATAC TCAGGGAACC TTTGATAGTC AGTCAACTTT GAGAGATTCA 
GCCACAGTAT TTGCCCTTAG CACAATGATC AGCTCAATAC AGGTATATAA CTTATCCCAA 
AATGTCCAGG AGGATGATCT TCAGCACCTC CAGCTTTTCA CTGAGTATGG CAGACTGGCA 
ATGGAGGAAA CATTCCTGAA GCCATTTCAG AGTCTGATAT TTCTTGTTCG AGACTGGAGT 
TTCCCATACG AATTTTCATA TGGAGCCGAT GGTGGTGCCA AATTCTTGGA AAAACGCCTC 
AAGGTCTCAG GGAACCAGCA TGAAGAACTA CAGAACGTCA GAAAACACAT CCATTCCTGT 
TTCACCAACA TTTCCTGTTT TCTGCTACCT CATCCTGGCT TAAAAGTAGC TACCAATCCA 
AACTTTGATG GAAAATTGAA AGAAATAGAT GATGAATTCA TCAAAAACTT GAAAATACTG 
ATTCCTTGGC TACTTAGTCC CGAGAGCCTA GATATTAAAG AGATCAATGG GAATAAAATC 
ACCTGCCGGG GTCTGGTGGA GTACTTCAAG GCTTATATAA AGATCTATCA AGGTGAAGAA 
TTACCACATC CCAAATCCAT GTTACAGGCC ACAGCAGAAG CTAACAATTT AGCAGCCGTG 
GCAACTGCCA AGGACACATA CAACAAAAAA ATGGAAGAGA TTTGTGGTGG TGACAAACCA 
TTTCTGGCCC CAAATGACTT GCAGACCAAA CACCTGCAAC TTAAGGAAGA ATCTGTGAAG 
CTATTCCGAG GGGTGAAGAA GATGGGTGGG GAAGAATTTA GCCGGCGTTA CCTGCAGCAG 
TTGGAGAGTG AAATAGATGA ACTTTACATC CAATATATCA AGCACAATGA TAGCAAAAAT 
ATCTTCCATG CAGCTCGTAC CCCAGCCACA CTGTTTGTAG TCATCTTTAT CACATATGTG 
ATTGCTGGTG TGACTGGATT CATTGGTTTG GACATCATAG CTAGCCTATG CAATATGATA 
ATGGGACTGA CCCTTATCAC CCTGTGCACT TGGGCATATA TCCGGTACTC TGGAGAATAC 
CGAGAGCTGG GAGCTGTAAT AGACCAGGTG GCTGCAGCTC TGTGGGACCA GGGAAGTACA 
AATGAGGCTT TGTACAAGCT TTACAGTGCA GCAGCAACCC ACAGACATCT GTATCATCAA 
GCTTTCCCTA CACCAAAGTC GGAATCTACT GAACAATCAG AAAAGAAAAA AATGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Disease-Causing Variants in the ATL1 Gene Are a Rare Cause of Hereditary Spastic Paraplegia among Czech Patients.
Annals of human genetics81(6)249-257(2017 Nov)
M?sz?rosov? AU,Gre?malov? D,Br?zdilov? M,Dvo???kov? N,Kalina Z,?erm?kov? M,V?vrov? D,Smetanov? I,Stan?k D,Seeman P

The crossover conformational shift of the GTPase atlastin provides the energy driving ER fusion.
The Journal of cell biology216(5)1321-1335(2017 May)
Winsor J,Hackney DD,Lee TH

Atlastin regulates store-operated calcium entry for nerve growth factor-induced neurite outgrowth.
Scientific reports743490(2017 Feb)
Li J,Yan B,Si H,Peng X,Zhang SL,Hu J

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ATL1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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