Cnih2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Cnih2
Entrez Gene ID	361705
Full Name	cornichon family AMPA receptor auxiliary protein 2
Synonyms	CNIH-2,Cnih3,RGD1304930
General protein information	Preferred Names cornichon family AMPA receptor auxiliary protein 2 Names protein cornichon homolog 2 cornichon homolog 2 cornichon homolog 3 cornichon-like protein
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 1 Map Location: 1q43

mRNA and Protein(s)

mRNA	Protein	Name
XM_017589439.1	XP_017444928.1	protein cornichon homolog 2 isoform X2
XM_017589438.1	XP_017444927.1	protein cornichon homolog 2 isoform X1
XM_017589440.1	XP_017444929.1	protein cornichon homolog 2 isoform X3
NM_001025132.1	NP_001020303.1	protein cornichon homolog 2
XM_017589437.1	XP_017444926.1	protein cornichon homolog 2 isoform X1
XM_008760154.2	XP_008758376.1	protein cornichon homolog 2 isoform X4

Pathways from BioSystems

Homologies

Homo sapiens (human)	CNIH2	NP_872359.1
Rattus norvegicus (Norway rat)	Cnih2	NP_001020303.1
	LOC721848	XP_001118044.1
Xenopus tropicalis (tropical clawed frog)	cnih2	NP_001072219.1
Canis lupus familiaris (dog)	CNIH2	XP_003432365.1
Mus musculus (house mouse)	Cnih2	NP_034050.1
Danio rerio (zebrafish)	cnih2	NP_001013542.1
Pan troglodytes (chimpanzee)	CNIH2	XP_001150473.2

Gene Ontology
Bibliography

Related articles in PubMed

Cornichon2 dictates the time course of excitatory transmission at individual hippocampal synapses.
Boudkkazi S, Brechet A, Schwenk J, Fakler B
Neuron82(4)848-58(2014 May)

Cornichons control ER export of AMPA receptors to regulate synaptic excitability.
Brockie PJ, Jensen M, Mellem JE, Jensen E, Yamasaki T, Wang R, Maxfield D, Thacker C, Hoerndli F, Dunn PJ, Tomita S, Madsen DM, Maricq AV
Neuron80(1)129-42(2013 Oct)

AMPA receptors commandeer an ancient cargo exporter for use as an auxiliary subunit for signaling.
Harmel N, Cokic B, Zolles G, Berkefeld H, Mauric V, Fakler B, Stein V, Kl?cker N
PloS one7(1)e30681(2012)

Cornichon-2 modulates AMPA receptor-transmembrane AMPA receptor regulatory protein assembly to dictate gating and pharmacology.
Gill MB, Kato AS, Roberts MF, Yu H, Wang H, Tomita S, Bredt DS
The Journal of neuroscience : the official journal of the Society for Neuroscience31(18)6928-38(2011 May)

Hippocampal AMPA receptor gating controlled by both TARP and cornichon proteins.
Kato AS, Gill MB, Ho MT, Yu H, Tu Y, Siuda ER, Wang H, Qian YW, Nisenbaum ES, Tomita S, Bredt DS
Neuron68(6)1082-96(2010 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Mammalian AMPARs commandeer CNIH-2 for use as a bona fide auxiliary subunit that is able to modify receptor signaling.
Title: AMPA receptors commandeer an ancient cargo exporter for use as an auxiliary subunit for signaling.

CNIH-2 modulates neuronal AMPA receptor auxiliary subunit assembly by regulating the number of transmembrane AMPA receptor regulatory proteins within an AMPA receptor complex to modulate receptor gating and pharmacology.
Title: Cornichon-2 modulates AMPA receptor-transmembrane AMPA receptor regulatory protein assembly to dictate gating and pharmacology.

findings show that the majority of AMPARs in the brain are coassembled with CNIH-2 & CNIH-3; cornichons increase surface expression of AMPARs, & alter channel gating by markedly slowing deactivation & desensitization kinetics
Title: Functional proteomics identify cornichon proteins as auxiliary subunits of AMPA receptors.

The following Cnih2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cnih2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa07305	NM_001025132.1 Latest version!	Rattus norvegicus cornichon family AMPA receptor auxiliary protein 2 (Cnih2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
ORa47992	XM_008760154.2 Latest version!	Rattus norvegicus cornichon family AMPA receptor auxiliary protein 2 (Cnih2), transcript variant X5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
ORa56729	XM_017589437.1 Latest version!	Rattus norvegicus cornichon family AMPA receptor auxiliary protein 2 (Cnih2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
ORa56729	XM_017589438.1 Latest version!	Rattus norvegicus cornichon family AMPA receptor auxiliary protein 2 (Cnih2), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
ORa56730	XM_017589439.1 Latest version!	Rattus norvegicus cornichon family AMPA receptor auxiliary protein 2 (Cnih2), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
ORa56731	XM_017589440.1 Latest version!	Rattus norvegicus cornichon family AMPA receptor auxiliary protein 2 (Cnih2), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Cnih2 ( NM_001025132.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001020303.1 Rattus norvegicus cornichon family AMPA receptor auxiliary protein 2 (Cnih2), mRNA.

Price & Availability↑

CloneID	ORa07305
Clone ID Related Accession (Same CDS sequence)	NM_001025132.1
Accession Version	NM_001025132.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 483bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-08-03
Organism	Rattus norvegicus(Norway rat)
Product	protein cornichon homolog 2
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC091325.1. On Jul 1, 2005 this sequence version replaced XM_341989.2. ##Evidence-Data-START## Transcript exon combination :: BC091325.1, DY311867.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296 [ECO:0000348] ##Evidence-Data-END##

ATGGCGTTCA CCTTCGCAGC ATTCTGCTAC ATGCTCACCC TGGTGCTGTG CGCCTCCCTC 
ATCTTCTTTG TCATCTGGCA CATCATAGCC TTTGATGAGC TGCGGACTGA CTTCAAGAAC 
CCCATCGACC AGGGGAACCC AGCGCGGGCA CGCGAGCGTT TGAAAAACAT CGAACGCATC 
TGCTGCCTCC TGAGGAAGCT GGTGGTCCCG GAATATTCCA TCCACGGCCT CTTCTGTCTG 
ATGTTTCTGT GTGCAGCAGA GTGGGTGACC CTGGGCCTCA ACATCCCCCT CCTCTTCTAC 
CACCTCTGGA GGTACTTCCA CCGTCCTGCG GATGGCTCTG AGGTCATGTA TGATGCGGTC 
TCTATCATGA ATGCTGACAT CCTCAACTAC TGCCAGAAGG AGTCCTGGTG CAAACTCGCC 
TTCTACCTGC TCTCCTTCTT CTATTACCTG TACAGTATGG TTTATACGTT GGTGAGCTTC 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001020303.1
CDS	252..734
Translation	MAFTFAAFCYMLTLVLCASLIFFVIWHIIAFDELRTDFKNPIDQGNPARARERLKNIERICCLLRKLVVPEYSIHGLFCLMFLCAAEWVTLGLNIPLLFYHLWRYFHRPADGSEVMYDAVSIMNADILNYCQKESWCKLAFYLLSFFYYLYSMVYTLVSF

Target ORF information:

RefSeq Version	NM_001025132.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus cornichon family AMPA receptor auxiliary protein 2 (Cnih2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001025132.1

ORF Insert Sequence:

ATGGCGTTCA CCTTCGCAGC ATTCTGCTAC ATGCTCACCC TGGTGCTGTG CGCCTCCCTC 
ATCTTCTTTG TCATCTGGCA CATCATAGCC TTTGATGAGC TGCGGACTGA CTTCAAGAAC 
CCCATCGACC AGGGGAACCC AGCGCGGGCA CGCGAGCGTT TGAAAAACAT CGAACGCATC 
TGCTGCCTCC TGAGGAAGCT GGTGGTCCCG GAATATTCCA TCCACGGCCT CTTCTGTCTG 
ATGTTTCTGT GTGCAGCAGA GTGGGTGACC CTGGGCCTCA ACATCCCCCT CCTCTTCTAC 
CACCTCTGGA GGTACTTCCA CCGTCCTGCG GATGGCTCTG AGGTCATGTA TGATGCGGTC 
TCTATCATGA ATGCTGACAT CCTCAACTAC TGCCAGAAGG AGTCCTGGTG CAAACTCGCC 
TTCTACCTGC TCTCCTTCTT CTATTACCTG TACAGTATGG TTTATACGTT GGTGAGCTTC 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cnih2 ( XM_008760154.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008758376.1 Rattus norvegicus cornichon family AMPA receptor auxiliary protein 2 (Cnih2), transcript variant X5, mRNA.

Price & Availability↑

CloneID	ORa47992
Clone ID Related Accession (Same CDS sequence)	XM_008760154.2
Accession Version	XM_008760154.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 513bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	protein cornichon homolog 2 isoform X4
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008760154.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGTTCA CCTTCGCAGC ATTCTGCTAC ATGCTCACCC TGGTGCTGTG CGCCTCCCTC 
ATCTTCTTTG TCATCTGGCA CATCATAGCC TTTGATGAGC TGCGGACTGA CTTCAAGAAC 
CCCATCGACC AGGGGAACCC AGCGCGGGCA CGCGAGCGTT TGAAAAACAT CGAACGCATC 
TGCTGCCTCC TGAGGAAGAC TACTGACGTC TCACCCTCAC TCCCTCAGCT GGTGGTCCCG 
GAATATTCCA TCCACGGCCT CTTCTGTCTG ATGTTTCTGT GTGCAGCAGA GTGGGTGACC 
CTGGGCCTCA ACATCCCCCT CCTCTTCTAC CACCTCTGGA GGTACTTCCA CCGTCCTGCG 
GATGGCTCTG AGGTCATGTA TGATGCGGTC TCTATCATGA ATGCTGACAT CCTCAACTAC 
TGCCAGAAGG AGTCCTGGTG CAAACTCGCC TTCTACCTGC TCTCCTTCTT CTATTACCTG 
TACAGTATGG TTTATACGTT GGTGAGCTTC TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008758376.1
CDS	843..1355
Translation	MAFTFAAFCYMLTLVLCASLIFFVIWHIIAFDELRTDFKNPIDQGNPARARERLKNIERICCLLRKTTDVSPSLPQLVVPEYSIHGLFCLMFLCAAEWVTLGLNIPLLFYHLWRYFHRPADGSEVMYDAVSIMNADILNYCQKESWCKLAFYLLSFFYYLYSMVYTLVSF

Target ORF information:

RefSeq Version	XM_008760154.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus cornichon family AMPA receptor auxiliary protein 2 (Cnih2), transcript variant X5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008760154.2

ORF Insert Sequence:

ATGGCGTTCA CCTTCGCAGC ATTCTGCTAC ATGCTCACCC TGGTGCTGTG CGCCTCCCTC 
ATCTTCTTTG TCATCTGGCA CATCATAGCC TTTGATGAGC TGCGGACTGA CTTCAAGAAC 
CCCATCGACC AGGGGAACCC AGCGCGGGCA CGCGAGCGTT TGAAAAACAT CGAACGCATC 
TGCTGCCTCC TGAGGAAGAC TACTGACGTC TCACCCTCAC TCCCTCAGCT GGTGGTCCCG 
GAATATTCCA TCCACGGCCT CTTCTGTCTG ATGTTTCTGT GTGCAGCAGA GTGGGTGACC 
CTGGGCCTCA ACATCCCCCT CCTCTTCTAC CACCTCTGGA GGTACTTCCA CCGTCCTGCG 
GATGGCTCTG AGGTCATGTA TGATGCGGTC TCTATCATGA ATGCTGACAT CCTCAACTAC 
TGCCAGAAGG AGTCCTGGTG CAAACTCGCC TTCTACCTGC TCTCCTTCTT CTATTACCTG 
TACAGTATGG TTTATACGTT GGTGAGCTTC TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cnih2 ( XM_017589438.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017444927.1 Rattus norvegicus cornichon family AMPA receptor auxiliary protein 2 (Cnih2), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa56729
Clone ID Related Accession (Same CDS sequence)	XM_017589438.1 , XM_017589437.1
Accession Version	XM_017589438.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 513bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	protein cornichon homolog 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGATGC GGGTGAAGGC CCCTCCATGG CGACAGTCAC CATGGGGACG GCGGGCTGCT 
TTCCTGAGAA GACACCGCAG AGAGTTCTGG CGCCCTCTGG TGACCACACT CGGGGCCGTG 
GGAGGCGCCC TGGTTTCTGC TCCTTGGCTT CCCTTATCTA GGCCCTTTCC TTCCCTACAG 
CGCGAGCGTT TGAAAAACAT CGAACGCATC TGCTGCCTCC TGAGGAAGCT GGTGGTCCCG 
GAATATTCCA TCCACGGCCT CTTCTGTCTG ATGTTTCTGT GTGCAGCAGA GTGGGTGACC 
CTGGGCCTCA ACATCCCCCT CCTCTTCTAC CACCTCTGGA GGTACTTCCA CCGTCCTGCG 
GATGGCTCTG AGGTCATGTA TGATGCGGTC TCTATCATGA ATGCTGACAT CCTCAACTAC 
TGCCAGAAGG AGTCCTGGTG CAAACTCGCC TTCTACCTGC TCTCCTTCTT CTATTACCTG 
TACAGTATGG TTTATACGTT GGTGAGCTTC TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017444927.1
CDS	464..976
Translation	MEMRVKAPPWRQSPWGRRAAFLRRHRREFWRPLVTTLGAVGGALVSAPWLPLSRPFPSLQRERLKNIERICCLLRKLVVPEYSIHGLFCLMFLCAAEWVTLGLNIPLLFYHLWRYFHRPADGSEVMYDAVSIMNADILNYCQKESWCKLAFYLLSFFYYLYSMVYTLVSF

Target ORF information:

RefSeq Version	XM_017589438.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus cornichon family AMPA receptor auxiliary protein 2 (Cnih2), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017589438.1

ORF Insert Sequence:

ATGGAGATGC GGGTGAAGGC CCCTCCATGG CGACAGTCAC CATGGGGACG GCGGGCTGCT 
TTCCTGAGAA GACACCGCAG AGAGTTCTGG CGCCCTCTGG TGACCACACT CGGGGCCGTG 
GGAGGCGCCC TGGTTTCTGC TCCTTGGCTT CCCTTATCTA GGCCCTTTCC TTCCCTACAG 
CGCGAGCGTT TGAAAAACAT CGAACGCATC TGCTGCCTCC TGAGGAAGCT GGTGGTCCCG 
GAATATTCCA TCCACGGCCT CTTCTGTCTG ATGTTTCTGT GTGCAGCAGA GTGGGTGACC 
CTGGGCCTCA ACATCCCCCT CCTCTTCTAC CACCTCTGGA GGTACTTCCA CCGTCCTGCG 
GATGGCTCTG AGGTCATGTA TGATGCGGTC TCTATCATGA ATGCTGACAT CCTCAACTAC 
TGCCAGAAGG AGTCCTGGTG CAAACTCGCC TTCTACCTGC TCTCCTTCTT CTATTACCTG 
TACAGTATGG TTTATACGTT GGTGAGCTTC TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cnih2 ( XM_017589437.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017444926.1 Rattus norvegicus cornichon family AMPA receptor auxiliary protein 2 (Cnih2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa56729
Clone ID Related Accession (Same CDS sequence)	XM_017589438.1 , XM_017589437.1
Accession Version	XM_017589437.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 513bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	protein cornichon homolog 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGATGC GGGTGAAGGC CCCTCCATGG CGACAGTCAC CATGGGGACG GCGGGCTGCT 
TTCCTGAGAA GACACCGCAG AGAGTTCTGG CGCCCTCTGG TGACCACACT CGGGGCCGTG 
GGAGGCGCCC TGGTTTCTGC TCCTTGGCTT CCCTTATCTA GGCCCTTTCC TTCCCTACAG 
CGCGAGCGTT TGAAAAACAT CGAACGCATC TGCTGCCTCC TGAGGAAGCT GGTGGTCCCG 
GAATATTCCA TCCACGGCCT CTTCTGTCTG ATGTTTCTGT GTGCAGCAGA GTGGGTGACC 
CTGGGCCTCA ACATCCCCCT CCTCTTCTAC CACCTCTGGA GGTACTTCCA CCGTCCTGCG 
GATGGCTCTG AGGTCATGTA TGATGCGGTC TCTATCATGA ATGCTGACAT CCTCAACTAC 
TGCCAGAAGG AGTCCTGGTG CAAACTCGCC TTCTACCTGC TCTCCTTCTT CTATTACCTG 
TACAGTATGG TTTATACGTT GGTGAGCTTC TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017444926.1
CDS	321..833
Translation	MEMRVKAPPWRQSPWGRRAAFLRRHRREFWRPLVTTLGAVGGALVSAPWLPLSRPFPSLQRERLKNIERICCLLRKLVVPEYSIHGLFCLMFLCAAEWVTLGLNIPLLFYHLWRYFHRPADGSEVMYDAVSIMNADILNYCQKESWCKLAFYLLSFFYYLYSMVYTLVSF

Target ORF information:

RefSeq Version	XM_017589437.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus cornichon family AMPA receptor auxiliary protein 2 (Cnih2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017589437.1

ORF Insert Sequence:

ATGGAGATGC GGGTGAAGGC CCCTCCATGG CGACAGTCAC CATGGGGACG GCGGGCTGCT 
TTCCTGAGAA GACACCGCAG AGAGTTCTGG CGCCCTCTGG TGACCACACT CGGGGCCGTG 
GGAGGCGCCC TGGTTTCTGC TCCTTGGCTT CCCTTATCTA GGCCCTTTCC TTCCCTACAG 
CGCGAGCGTT TGAAAAACAT CGAACGCATC TGCTGCCTCC TGAGGAAGCT GGTGGTCCCG 
GAATATTCCA TCCACGGCCT CTTCTGTCTG ATGTTTCTGT GTGCAGCAGA GTGGGTGACC 
CTGGGCCTCA ACATCCCCCT CCTCTTCTAC CACCTCTGGA GGTACTTCCA CCGTCCTGCG 
GATGGCTCTG AGGTCATGTA TGATGCGGTC TCTATCATGA ATGCTGACAT CCTCAACTAC 
TGCCAGAAGG AGTCCTGGTG CAAACTCGCC TTCTACCTGC TCTCCTTCTT CTATTACCTG 
TACAGTATGG TTTATACGTT GGTGAGCTTC TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cnih2 ( XM_017589439.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017444928.1 Rattus norvegicus cornichon family AMPA receptor auxiliary protein 2 (Cnih2), transcript variant X3, mRNA.

Price & Availability↑

CloneID	ORa56730
Clone ID Related Accession (Same CDS sequence)	XM_017589439.1
Accession Version	XM_017589439.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 435bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	protein cornichon homolog 2 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGTTCA CCTTCGCAGC ATTCTGCTAC ATGCTCACCC TGGTGCTGTG CGCCTCCCTC 
ATCTTCTTTG TCATCTGGCA CATCATAGCC TTTGATGAGC TGCGGACTGA CTTCAAGAAC 
CCCATCGACC AGGGGAACCC AGCGCGGGCA CTGGTGGTCC CGGAATATTC CATCCACGGC 
CTCTTCTGTC TGATGTTTCT GTGTGCAGCA GAGTGGGTGA CCCTGGGCCT CAACATCCCC 
CTCCTCTTCT ACCACCTCTG GAGGTACTTC CACCGTCCTG CGGATGGCTC TGAGGTCATG 
TATGATGCGG TCTCTATCAT GAATGCTGAC ATCCTCAACT ACTGCCAGAA GGAGTCCTGG 
TGCAAACTCG CCTTCTACCT GCTCTCCTTC TTCTATTACC TGTACAGTAT GGTTTATACG 
TTGGTGAGCT TCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017444928.1
CDS	843..1277
Translation	MAFTFAAFCYMLTLVLCASLIFFVIWHIIAFDELRTDFKNPIDQGNPARALVVPEYSIHGLFCLMFLCAAEWVTLGLNIPLLFYHLWRYFHRPADGSEVMYDAVSIMNADILNYCQKESWCKLAFYLLSFFYYLYSMVYTLVSF

Target ORF information:

RefSeq Version	XM_017589439.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus cornichon family AMPA receptor auxiliary protein 2 (Cnih2), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017589439.1

ORF Insert Sequence:

ATGGCGTTCA CCTTCGCAGC ATTCTGCTAC ATGCTCACCC TGGTGCTGTG CGCCTCCCTC 
ATCTTCTTTG TCATCTGGCA CATCATAGCC TTTGATGAGC TGCGGACTGA CTTCAAGAAC 
CCCATCGACC AGGGGAACCC AGCGCGGGCA CTGGTGGTCC CGGAATATTC CATCCACGGC 
CTCTTCTGTC TGATGTTTCT GTGTGCAGCA GAGTGGGTGA CCCTGGGCCT CAACATCCCC 
CTCCTCTTCT ACCACCTCTG GAGGTACTTC CACCGTCCTG CGGATGGCTC TGAGGTCATG 
TATGATGCGG TCTCTATCAT GAATGCTGAC ATCCTCAACT ACTGCCAGAA GGAGTCCTGG 
TGCAAACTCG CCTTCTACCT GCTCTCCTTC TTCTATTACC TGTACAGTAT GGTTTATACG 
TTGGTGAGCT TCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cnih2 ( XM_017589440.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017444929.1 Rattus norvegicus cornichon family AMPA receptor auxiliary protein 2 (Cnih2), transcript variant X4, mRNA.

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CloneID	ORa56731
Clone ID Related Accession (Same CDS sequence)	XM_017589440.1
Accession Version	XM_017589440.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 348bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	protein cornichon homolog 2 isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTGCTGTG CTGAGCGCGA GCGTTTGAAA AACATCGAAC GCATCTGCTG CCTCCTGAGG 
AAGCTGGTGG TCCCGGAATA TTCCATCCAC GGCCTCTTCT GTCTGATGTT TCTGTGTGCA 
GCAGAGTGGG TGACCCTGGG CCTCAACATC CCCCTCCTCT TCTACCACCT CTGGAGGTAC 
TTCCACCGTC CTGCGGATGG CTCTGAGGTC ATGTATGATG CGGTCTCTAT CATGAATGCT 
GACATCCTCA ACTACTGCCA GAAGGAGTCC TGGTGCAAAC TCGCCTTCTA CCTGCTCTCC 
TTCTTCTATT ACCTGTACAG TATGGTTTAT ACGTTGGTGA GCTTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017444929.1
CDS	105..452
Translation	MCCAERERLKNIERICCLLRKLVVPEYSIHGLFCLMFLCAAEWVTLGLNIPLLFYHLWRYFHRPADGSEVMYDAVSIMNADILNYCQKESWCKLAFYLLSFFYYLYSMVYTLVSF

Target ORF information:

RefSeq Version	XM_017589440.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus cornichon family AMPA receptor auxiliary protein 2 (Cnih2), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017589440.1

ORF Insert Sequence:

ATGTGCTGTG CTGAGCGCGA GCGTTTGAAA AACATCGAAC GCATCTGCTG CCTCCTGAGG 
AAGCTGGTGG TCCCGGAATA TTCCATCCAC GGCCTCTTCT GTCTGATGTT TCTGTGTGCA 
GCAGAGTGGG TGACCCTGGG CCTCAACATC CCCCTCCTCT TCTACCACCT CTGGAGGTAC 
TTCCACCGTC CTGCGGATGG CTCTGAGGTC ATGTATGATG CGGTCTCTAT CATGAATGCT 
GACATCCTCA ACTACTGCCA GAAGGAGTCC TGGTGCAAAC TCGCCTTCTA CCTGCTCTCC 
TTCTTCTATT ACCTGTACAG TATGGTTTAT ACGTTGGTGA GCTTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Cornichon2 dictates the time course of excitatory transmission at individual hippocampal synapses.
Neuron82(4)848-58(2014 May)
Boudkkazi S,Brechet A,Schwenk J,Fakler B

Cornichons control ER export of AMPA receptors to regulate synaptic excitability.
Neuron80(1)129-42(2013 Oct)
Brockie PJ,Jensen M,Mellem JE,Jensen E,Yamasaki T,Wang R,Maxfield D,Thacker C,Hoerndli F,Dunn PJ,Tomita S,Madsen DM,Maricq AV

AMPA receptors commandeer an ancient cargo exporter for use as an auxiliary subunit for signaling.
PloS one7(1)e30681(2012)
Harmel N,Cokic B,Zolles G,Berkefeld H,Mauric V,Fakler B,Stein V,Kl?cker N

Cornichon-2 modulates AMPA receptor-transmembrane AMPA receptor regulatory protein assembly to dictate gating and pharmacology.
The Journal of neuroscience : the official journal of the Society for Neuroscience31(18)6928-38(2011 May)
Gill MB,Kato AS,Roberts MF,Yu H,Wang H,Tomita S,Bredt DS

Hippocampal AMPA receptor gating controlled by both TARP and cornichon proteins.
Neuron68(6)1082-96(2010 Dec)
Kato AS,Gill MB,Ho MT,Yu H,Tu Y,Siuda ER,Wang H,Qian YW,Nisenbaum ES,Tomita S,Bredt DS

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Cnih2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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