Cdc6 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Cdc6
Entrez Gene ID	360621
Full Name	cell division cycle 6
General protein information	Preferred Names cell division cycle 6 Names cell division control protein 6 homolog cell division cycle 6 homolog
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 10 Map Location: 10q31

mRNA and Protein(s)

mRNA	Protein	Name
XM_006247355.3	XP_006247417.1	cell division control protein 6 homolog isoform X2
XM_006247354.3	XP_006247416.1	cell division control protein 6 homolog isoform X1
NM_001108298.1	NP_001101768.1	cell division control protein 6 homolog

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Cdc6	NP_001101768.1
Oryza sativa (rice)	Os01g0856000	NP_001044845.2
Homo sapiens (human)	CDC6	NP_001245.1
Pan troglodytes (chimpanzee)	CDC6	XP_001170494.1
	CDC6	XP_001096984.1
Mus musculus (house mouse)	Cdc6	NP_001020950.1
Gallus gallus (chicken)	LOC100857489	XP_004948700.1
Danio rerio (zebrafish)	cdc6	NP_001120805.1
Arabidopsis thaliana (thale cress)	AT1G07270	NP_172207.2
Xenopus tropicalis (tropical clawed frog)	cdc6	NP_001007994.1
Canis lupus familiaris (dog)	CDC6	XP_005624591.1
Bos taurus (cattle)	CDC6	NP_001179336.1
Drosophila melanogaster (fruit fly)	Cdc6	NP_648247.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP005176	XP_314072.3
Arabidopsis thaliana (thale cress)	CDC6	NP_850137.1

Gene Ontology
Bibliography

Related articles in PubMed

Expression of CDc6 after acute spinal cord injury in adult rats.
Chen C, Lu J, Yu Q, Xiao JR, Wei HF, Song XJ, Ge JB, Tao WD, Qian R, Yu XW, Zhao J
Neuropeptides5659-67(2016 Apr)

Recruitment of the human Cdt1 replication licensing protein by the loop domain of Hec1 is required for stable kinetochore-microtubule attachment.
Varma D, Chandrasekaran S, Sundin LJ, Reidy KT, Wan X, Chasse DA, Nevis KR, DeLuca JG, Salmon ED, Cook JG
Nature cell biology14(6)593-603(2012 May)

Cdc6 protein activates p27KIP1-bound Cdk2 protein only after the bound p27 protein undergoes C-terminal phosphorylation.
Uranbileg B, Yamamoto H, Park JH, Mohanty AR, Arakawa-Takeuchi S, Jinno S, Okayama H
The Journal of biological chemistry287(9)6275-83(2012 Feb)

Interactions of MCP1 with components of the replication machinery in mammalian cells.
Bronze-da-Rocha E, Lin CM, Shimura T, Aladjem MI
International journal of biological sciences7(2)193-208(2011 Feb)

Cell division cycle 6, a mitotic substrate of polo-like kinase 1, regulates chromosomal segregation mediated by cyclin-dependent kinase 1 and separase.
Yim H, Erikson RL
Proceedings of the National Academy of Sciences of the United States of America107(46)19742-7(2010 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Cell division cycle 6 might play crucial roles in central nervous system pathophysiology after spinal cord injury.
Title: Expression of CDc6 after acute spinal cord injury in adult rats.

Activation of mTORC1 overrides the absence of the anchorage and stabilizes Cdc6 at least partly via activating Cdk4/6 that induces Emi1, an APC/C(Cdh1) ubiquitin ligase inhibitor.
Title: Mammalian target of rapamycin complex 1 signaling opposes the effects of anchorage loss, leading to activation of Cdk4 and Cdc6 stabilization.

Cdc6 protein can activate p21-associated Cdk2 in an ATP-dependent manner in vitro.
Title: ATP-dependent activation of p21WAF1/CIP1-associated Cdk2 by Cdc6.

The following Cdc6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cdc6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa07090	NM_001108298.1 Latest version!	Rattus norvegicus cell division cycle 6 (Cdc6), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
ORa33714	XM_006247354.3 Latest version!	Rattus norvegicus cell division cycle 6 (Cdc6), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
ORa33715	XM_006247355.3 Latest version!	Rattus norvegicus cell division cycle 6 (Cdc6), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Cdc6 ( NM_001108298.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001101768.1 Rattus norvegicus cell division cycle 6 (Cdc6), mRNA.

Price & Availability↑

CloneID	ORa07090
Clone ID Related Accession (Same CDS sequence)	NM_001108298.1
Accession Version	NM_001108298.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1686bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-26
Organism	Rattus norvegicus(Norway rat)
Product	cell division control protein 6 homolog
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473948.1. On or before Oct 4, 2007 this sequence version replaced XM_340896.3, XM_001081412.1. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMN01906347, SAMN02642645 [ECO:0000348] ##Evidence-Data-END##

ATGCCTCAAA CCCGATCCCA GACACAAGCT ACCATCGACT TTCCGAAAAA GAAGCAATCT 
AAGACCCTGA GCAAGACAAA CTCCCGTGAC AGTGAAGTAA AACTTAGAAA CGTCCAGCCT 
GTACCCACCA CTCCGTGTGC GGACATAAAA ATTCTGCCTC TCAGTCCCCG AAAACGTTTG 
GGTGATGACA ATCTGTGCAA CACTCCCCAT TTATCTCCAT GTTCTCCGCC CAAGCTGGGC 
AGGAAGGAAA ACGGCCCCCC TCGCTCACAT ACACGGAAGG GATGCAGATT AATATTCGAT 
GATGAGCTGG CAGTTAAGGC TTCCGCCCCA AAAGAACAAG ACAGAGTTCC CCAGCACCAA 
ATACTTTCCT CCGCTCAAAG AGGTCAAGAG AGCGAAACAA ATCCTGAGCA GAAATGCCCA 
CCAGAGAAGG AATCCGCGTG TATGCGACTG TTCAAGCAGG AAGGCACTTG CTATCAACAG 
GCAAAGCTTG TCCTGAATAC AGCTGTCCCG GACCGGCTGC CTGCCAGAGA ACAGGAGATG 
GGTGTCATCA GGGATTTCCT GAAGGAGCAC ATCTGTGGGA AAAAAGCTGG GAGTCTCTAC 
CTTTCTGGCG CTCCTGGAAC TGGGAAAACT GCCTGTTTAA GCCGGATTCT GCAGGACTTC 
AAGAAGGAAG TGAAAGGCTT TAAAACTATC GTGCTGAATT GCATGTCCCT GAGGAACGCT 
CAGGCCGTGT TCCCAGCCAT TGCTCAGGAG ATTGGTCGGG AGGAACTCTG CAGACCCACC 
GGGAAGGACT TGATGAGAAA GCTGGAAAAG CACTTGACAG CCGAGAGGGG CCCCATGATT 
GTGTTGGTGT TGGACGAGAT GGATCAGCTG GACAGCAAAG GGCAGGATGT GTTATACACC 
CTGTTTGAGT GGCCGTGGTT AAGCAATTCC CGATTGGTGC TCATTGGTAT TGCTAATACC 
CTGGATCTCA CGGACAGAAT TCTGCCGAGA CTTGAAGCTA GAGAAGGCTG TAAGCCGAAG 
CTACTGAACT TCCCACCTTA CACCAGGAAT CAGATAGCTG CGATCTTGCA GGATAGGCTT 
AGTCAGGTAT CAAAAGACCA GGTTCTGGAC AGTGCTGCGA TTCAGTTCTG TGCCCGCAAA 
GTATCTGCTG TCTCAGGGGA CATCCGGAAA GCGCTGGATG TTTGCAGGCG AGCTATTGAA 
ATTGTGGAGT CGGATGTCAG GAGCCAGACA GTCCTCAAAC CACTCTCCGA ATGTAAATCA 
CCCTGCGAGT CGCTGGTTCC CAAGCGTGTC GGTCTCGCTC ACATATCCCA AGTCATTTCG 
GGAGTTGATG GTAACAGGGT GACTTTGAGC CAAGAAAACA CACAGGATTC CCTTCCTCTC 
CAGCAGAAGA TCTTGGTTTG CTCTTTGCTG CTCTTGACCA AGCGGCTAAA AATCAAAGAG 
GTCACCCTGG GGAAGTTATA TGAAGCCTAC AGTAGTGTCT GTCGTAAACA GCAGGTGGCA 
GCCGTAGACC AGTCTGAGTG TTTGTCCCTT TCTGGACTCC TGGAATCCAG GGGCATTGTG 
GGACTGAAGA AAAACAAGGA GAGCCGCCTC ACCAAGGTGT CTCTGAAGAT TGAAGAAAAG 
GAGATAGAGC ATGTCCTAAA AGGCAAAGCT TTCATTGGGA ACATCCTCGC TGCCGGGCTG 
CCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001101768.1
CDS	187..1872
Translation	MPQTRSQTQATIDFPKKKQSKTLSKTNSRDSEVKLRNVQPVPTTPCADIKILPLSPRKRLGDDNLCNTPHLSPCSPPKLGRKENGPPRSHTRKGCRLIFDDELAVKASAPKEQDRVPQHQILSSAQRGQESETNPEQKCPPEKESACMRLFKQEGTCYQQAKLVLNTAVPDRLPAREQEMGVIRDFLKEHICGKKAGSLYLSGAPGTGKTACLSRILQDFKKEVKGFKTIVLNCMSLRNAQAVFPAIAQEIGREELCRPTGKDLMRKLEKHLTAERGPMIVLVLDEMDQLDSKGQDVLYTLFEWPWLSNSRLVLIGIANTLDLTDRILPRLEAREGCKPKLLNFPPYTRNQIAAILQDRLSQVSKDQVLDSAAIQFCARKVSAVSGDIRKALDVCRRAIEIVESDVRSQTVLKPLSECKSPCESLVPKRVGLAHISQVISGVDGNRVTLSQENTQDSLPLQQKILVCSLLLLTKRLKIKEVTLGKLYEAYSSVCRKQQVAAVDQSECLSLSGLLESRGIVGLKKNKESRLTKVSLKIEEKEIEHVLKGKAFIGNILAAGLP

Target ORF information:

RefSeq Version	NM_001108298.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus cell division cycle 6 (Cdc6), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001108298.1

ORF Insert Sequence:

ATGCCTCAAA CCCGATCCCA GACACAAGCT ACCATCGACT TTCCGAAAAA GAAGCAATCT 
AAGACCCTGA GCAAGACAAA CTCCCGTGAC AGTGAAGTAA AACTTAGAAA CGTCCAGCCT 
GTACCCACCA CTCCGTGTGC GGACATAAAA ATTCTGCCTC TCAGTCCCCG AAAACGTTTG 
GGTGATGACA ATCTGTGCAA CACTCCCCAT TTATCTCCAT GTTCTCCGCC CAAGCTGGGC 
AGGAAGGAAA ACGGCCCCCC TCGCTCACAT ACACGGAAGG GATGCAGATT AATATTCGAT 
GATGAGCTGG CAGTTAAGGC TTCCGCCCCA AAAGAACAAG ACAGAGTTCC CCAGCACCAA 
ATACTTTCCT CCGCTCAAAG AGGTCAAGAG AGCGAAACAA ATCCTGAGCA GAAATGCCCA 
CCAGAGAAGG AATCCGCGTG TATGCGACTG TTCAAGCAGG AAGGCACTTG CTATCAACAG 
GCAAAGCTTG TCCTGAATAC AGCTGTCCCG GACCGGCTGC CTGCCAGAGA ACAGGAGATG 
GGTGTCATCA GGGATTTCCT GAAGGAGCAC ATCTGTGGGA AAAAAGCTGG GAGTCTCTAC 
CTTTCTGGCG CTCCTGGAAC TGGGAAAACT GCCTGTTTAA GCCGGATTCT GCAGGACTTC 
AAGAAGGAAG TGAAAGGCTT TAAAACTATC GTGCTGAATT GCATGTCCCT GAGGAACGCT 
CAGGCCGTGT TCCCAGCCAT TGCTCAGGAG ATTGGTCGGG AGGAACTCTG CAGACCCACC 
GGGAAGGACT TGATGAGAAA GCTGGAAAAG CACTTGACAG CCGAGAGGGG CCCCATGATT 
GTGTTGGTGT TGGACGAGAT GGATCAGCTG GACAGCAAAG GGCAGGATGT GTTATACACC 
CTGTTTGAGT GGCCGTGGTT AAGCAATTCC CGATTGGTGC TCATTGGTAT TGCTAATACC 
CTGGATCTCA CGGACAGAAT TCTGCCGAGA CTTGAAGCTA GAGAAGGCTG TAAGCCGAAG 
CTACTGAACT TCCCACCTTA CACCAGGAAT CAGATAGCTG CGATCTTGCA GGATAGGCTT 
AGTCAGGTAT CAAAAGACCA GGTTCTGGAC AGTGCTGCGA TTCAGTTCTG TGCCCGCAAA 
GTATCTGCTG TCTCAGGGGA CATCCGGAAA GCGCTGGATG TTTGCAGGCG AGCTATTGAA 
ATTGTGGAGT CGGATGTCAG GAGCCAGACA GTCCTCAAAC CACTCTCCGA ATGTAAATCA 
CCCTGCGAGT CGCTGGTTCC CAAGCGTGTC GGTCTCGCTC ACATATCCCA AGTCATTTCG 
GGAGTTGATG GTAACAGGGT GACTTTGAGC CAAGAAAACA CACAGGATTC CCTTCCTCTC 
CAGCAGAAGA TCTTGGTTTG CTCTTTGCTG CTCTTGACCA AGCGGCTAAA AATCAAAGAG 
GTCACCCTGG GGAAGTTATA TGAAGCCTAC AGTAGTGTCT GTCGTAAACA GCAGGTGGCA 
GCCGTAGACC AGTCTGAGTG TTTGTCCCTT TCTGGACTCC TGGAATCCAG GGGCATTGTG 
GGACTGAAGA AAAACAAGGA GAGCCGCCTC ACCAAGGTGT CTCTGAAGAT TGAAGAAAAG 
GAGATAGAGC ATGTCCTAAA AGGCAAAGCT TTCATTGGGA ACATCCTCGC TGCCGGGCTG 
CCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cdc6 ( XM_006247354.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006247416.1 Rattus norvegicus cell division cycle 6 (Cdc6), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa33714
Clone ID Related Accession (Same CDS sequence)	XM_006247354.3
Accession Version	XM_006247354.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1686bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	cell division control protein 6 homolog isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005109.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006247354.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCTCAAA CCCGATCCCA GACACAAGCT ACCATCGACT TTCCGAAAAA GAAGCAATCT 
AAGACCCTGA GCAAGACAAA CTCCCGTGAC AGTGAAGTAA AACTTAGAAA CGTCCAGCCT 
GTACCCACCA CTCCGTGTGC GGACATAAAA ATTCTGCCTC TCAGTCCCCG AAAACGTTTG 
GGTGATGACA ATCTGTGCAA CACTCCCCAT TTATCTCCAT GTTCTCCGCC CAAGCTGGGC 
AGGAAGGAAA ACGGCCCCCC TCGCTCACAT ACACGGAAGG GATGCAGATT AATATTCGAT 
GATGAGCTGG CAGTTAAGGC TTCCGCCCCA AAAGAACAAG ACAGAGTTCC CCAGCACCAA 
ATACTTTCCT CCGCTCAAAG AGGTCAAGAG AGCGAAACAA ATCCTGAGCA GAAATGCCCA 
CCAGAGAAGG AATCCGCGTG TATGCGACTG TTCAAGCAGG AAGGCACTTG CTATCAACAG 
GCAAAGCTTG TCCTGAATAC AGCTGTCCCG GACCGGCTGC CTGCCAGAGA ACAGGAGATG 
GGTGTCATCA GGGATTTCCT GAAGGAGCAC ATCTGTGGGA AAAAAGCTGG GAGTCTCTAC 
CTTTCTGGCG CTCCTGGAAC TGGGAAAACT GCCTGTTTAA GCCGGATTCT GCAGGACTTC 
AAGAAGGAAG TGAAAGGCTT TAAAACTATC GTGCTGAATT GCATGTCCCT GAGGAACGCT 
CAGGCCGTGT TCCCAGCCAT TGCTCAGGAG ATTGGTCGGG AGGAACTCTG CAGACCCACC 
GGGAAGGACT TGATGAGAAA GCTGGAAAAG CACTTGACAG CCGAGAGGGG CCCCATGATT 
GTGTTGGTGT TGGACGAGAT GGATCAGCTG GACAGCAAAG GGCAGGATGT GTTATACACA 
CTGTTTGAGT GGCCGTGGTT AAGCAATTCC CGATTGGTGC TCATTGGTAT TGCTAATACC 
CTGGATCTCA CGGACAGAAT TCTGCCGAGA CTTGAAGCTA GAGAAGGCTG TAAGCCGAAG 
CTACTGAACT TCCCACCTTA CACCAGGAAT CAGATAGCTG CGATCTTGCA GGATAGGCTT 
AGTCAGGTAT CAAAAGACCA GGTTCTGGAC AGTGCTGCGA TTCAGTTCTG TGCCCGCAAA 
GTATCTGCTG TCTCAGGGGA CATCCGGAAA GCGCTGGATG TTTGCAGGCG AGCTATTGAA 
ATTGTGGAGT CGGATGTCAG GAGCCAGACA GTCCTCAAAC CACTCTCCGA ATGTAAATCA 
CCCTGCGAGT CGCTGGTTCC CAAGCGTGTC GGTCTCGCTC ACATATCCCA AGTCATTTCG 
GGAGTTGATG GTAACAGGGT GACTTTGAGC CAAGAAAACA CACAGGATTC CCTTCCTCTC 
CAGCAGAAGA TCTTGGTTTG CTCTTTGCTG CTCTTGACCA AGCGGCTAAA AATCAAAGAG 
GTCACCCTGG GGAAGTTATA TGAAGCCTAC AGTAGTGTCT GTCGTAAACA GCAGGTGGCA 
GCCGTAGACC AGTCTGAGTG TTTGTCCCTT TCTGGACTCC TGGAATCCAG GGGCATTGTG 
GGACTGAAGA AAAACAAGGA GAGCCGCCTC ACCAAGGTGT CTCTGAAGAT TGAAGAAAAG 
GAGATAGAGC ATGTCCTAAA AGGCAAAGCT TTCATTGGGA ACATCCTCGC TGCCGGGCTG 
CCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006247416.1
CDS	285..1970
Translation	MPQTRSQTQATIDFPKKKQSKTLSKTNSRDSEVKLRNVQPVPTTPCADIKILPLSPRKRLGDDNLCNTPHLSPCSPPKLGRKENGPPRSHTRKGCRLIFDDELAVKASAPKEQDRVPQHQILSSAQRGQESETNPEQKCPPEKESACMRLFKQEGTCYQQAKLVLNTAVPDRLPAREQEMGVIRDFLKEHICGKKAGSLYLSGAPGTGKTACLSRILQDFKKEVKGFKTIVLNCMSLRNAQAVFPAIAQEIGREELCRPTGKDLMRKLEKHLTAERGPMIVLVLDEMDQLDSKGQDVLYTLFEWPWLSNSRLVLIGIANTLDLTDRILPRLEAREGCKPKLLNFPPYTRNQIAAILQDRLSQVSKDQVLDSAAIQFCARKVSAVSGDIRKALDVCRRAIEIVESDVRSQTVLKPLSECKSPCESLVPKRVGLAHISQVISGVDGNRVTLSQENTQDSLPLQQKILVCSLLLLTKRLKIKEVTLGKLYEAYSSVCRKQQVAAVDQSECLSLSGLLESRGIVGLKKNKESRLTKVSLKIEEKEIEHVLKGKAFIGNILAAGLP

Target ORF information:

RefSeq Version	XM_006247354.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus cell division cycle 6 (Cdc6), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006247354.3

ORF Insert Sequence:

ATGCCTCAAA CCCGATCCCA GACACAAGCT ACCATCGACT TTCCGAAAAA GAAGCAATCT 
AAGACCCTGA GCAAGACAAA CTCCCGTGAC AGTGAAGTAA AACTTAGAAA CGTCCAGCCT 
GTACCCACCA CTCCGTGTGC GGACATAAAA ATTCTGCCTC TCAGTCCCCG AAAACGTTTG 
GGTGATGACA ATCTGTGCAA CACTCCCCAT TTATCTCCAT GTTCTCCGCC CAAGCTGGGC 
AGGAAGGAAA ACGGCCCCCC TCGCTCACAT ACACGGAAGG GATGCAGATT AATATTCGAT 
GATGAGCTGG CAGTTAAGGC TTCCGCCCCA AAAGAACAAG ACAGAGTTCC CCAGCACCAA 
ATACTTTCCT CCGCTCAAAG AGGTCAAGAG AGCGAAACAA ATCCTGAGCA GAAATGCCCA 
CCAGAGAAGG AATCCGCGTG TATGCGACTG TTCAAGCAGG AAGGCACTTG CTATCAACAG 
GCAAAGCTTG TCCTGAATAC AGCTGTCCCG GACCGGCTGC CTGCCAGAGA ACAGGAGATG 
GGTGTCATCA GGGATTTCCT GAAGGAGCAC ATCTGTGGGA AAAAAGCTGG GAGTCTCTAC 
CTTTCTGGCG CTCCTGGAAC TGGGAAAACT GCCTGTTTAA GCCGGATTCT GCAGGACTTC 
AAGAAGGAAG TGAAAGGCTT TAAAACTATC GTGCTGAATT GCATGTCCCT GAGGAACGCT 
CAGGCCGTGT TCCCAGCCAT TGCTCAGGAG ATTGGTCGGG AGGAACTCTG CAGACCCACC 
GGGAAGGACT TGATGAGAAA GCTGGAAAAG CACTTGACAG CCGAGAGGGG CCCCATGATT 
GTGTTGGTGT TGGACGAGAT GGATCAGCTG GACAGCAAAG GGCAGGATGT GTTATACACA 
CTGTTTGAGT GGCCGTGGTT AAGCAATTCC CGATTGGTGC TCATTGGTAT TGCTAATACC 
CTGGATCTCA CGGACAGAAT TCTGCCGAGA CTTGAAGCTA GAGAAGGCTG TAAGCCGAAG 
CTACTGAACT TCCCACCTTA CACCAGGAAT CAGATAGCTG CGATCTTGCA GGATAGGCTT 
AGTCAGGTAT CAAAAGACCA GGTTCTGGAC AGTGCTGCGA TTCAGTTCTG TGCCCGCAAA 
GTATCTGCTG TCTCAGGGGA CATCCGGAAA GCGCTGGATG TTTGCAGGCG AGCTATTGAA 
ATTGTGGAGT CGGATGTCAG GAGCCAGACA GTCCTCAAAC CACTCTCCGA ATGTAAATCA 
CCCTGCGAGT CGCTGGTTCC CAAGCGTGTC GGTCTCGCTC ACATATCCCA AGTCATTTCG 
GGAGTTGATG GTAACAGGGT GACTTTGAGC CAAGAAAACA CACAGGATTC CCTTCCTCTC 
CAGCAGAAGA TCTTGGTTTG CTCTTTGCTG CTCTTGACCA AGCGGCTAAA AATCAAAGAG 
GTCACCCTGG GGAAGTTATA TGAAGCCTAC AGTAGTGTCT GTCGTAAACA GCAGGTGGCA 
GCCGTAGACC AGTCTGAGTG TTTGTCCCTT TCTGGACTCC TGGAATCCAG GGGCATTGTG 
GGACTGAAGA AAAACAAGGA GAGCCGCCTC ACCAAGGTGT CTCTGAAGAT TGAAGAAAAG 
GAGATAGAGC ATGTCCTAAA AGGCAAAGCT TTCATTGGGA ACATCCTCGC TGCCGGGCTG 
CCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cdc6 ( XM_006247355.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006247417.1 Rattus norvegicus cell division cycle 6 (Cdc6), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa33715
Clone ID Related Accession (Same CDS sequence)	XM_006247355.3
Accession Version	XM_006247355.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1683bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	cell division control protein 6 homolog isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005109.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006247355.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCTCAAA CCCGATCCCA GACACAAGCT ACCATCGACT TTCCGAAAAA GAAGCAATCT 
AAGACCCTGA GCAAGACAAA CTCCCGTGAC AGTGAAGTAA AACTTAGAAA CGTCCAGCCT 
GTACCCACCA CTCCGTGTGC GGACATAAAA ATTCTGCCTC TCAGTCCCCG AAAACGTTTG 
GGTGATGACA ATCTGTGCAA CACTCCCCAT TTATCTCCAT GTTCTCCGCC CAAGCTGGGC 
AGGAAGGAAA ACGGCCCCCC TCGCTCACAT ACACGGAAGG GATGCAGATT AATATTCGAT 
GATGAGCTGG CAGTTAAGGC TTCCGCCCCA AAAGAACAAG ACAGAGTTCC CCAGCACCAA 
ATACTTTCCT CCGCTCAAAG AGGTCAAGAG AGCGAAACAA ATCCTGAGCA GAAATGCCCA 
CCAGAGAAGG AATCCGCGTG TATGCGACTG TTCAAGCAGG AAGGCACTTG CTATCAACAG 
GCAAAGCTTG TCCTGAATAC AGCTGTCCCG GACCGGCTGC CTGCCAGAGA ACAGGAGATG 
GGTGTCATCA GGGATTTCCT GAAGGAGCAC ATCTGTGGGA AAAAAGCTGG GAGTCTCTAC 
CTTTCTGGCG CTCCTGGAAC TGGGAAAACT GCCTGTTTAA GCCGGATTCT GCAGGACTTC 
AAGGAAGTGA AAGGCTTTAA AACTATCGTG CTGAATTGCA TGTCCCTGAG GAACGCTCAG 
GCCGTGTTCC CAGCCATTGC TCAGGAGATT GGTCGGGAGG AACTCTGCAG ACCCACCGGG 
AAGGACTTGA TGAGAAAGCT GGAAAAGCAC TTGACAGCCG AGAGGGGCCC CATGATTGTG 
TTGGTGTTGG ACGAGATGGA TCAGCTGGAC AGCAAAGGGC AGGATGTGTT ATACACACTG 
TTTGAGTGGC CGTGGTTAAG CAATTCCCGA TTGGTGCTCA TTGGTATTGC TAATACCCTG 
GATCTCACGG ACAGAATTCT GCCGAGACTT GAAGCTAGAG AAGGCTGTAA GCCGAAGCTA 
CTGAACTTCC CACCTTACAC CAGGAATCAG ATAGCTGCGA TCTTGCAGGA TAGGCTTAGT 
CAGGTATCAA AAGACCAGGT TCTGGACAGT GCTGCGATTC AGTTCTGTGC CCGCAAAGTA 
TCTGCTGTCT CAGGGGACAT CCGGAAAGCG CTGGATGTTT GCAGGCGAGC TATTGAAATT 
GTGGAGTCGG ATGTCAGGAG CCAGACAGTC CTCAAACCAC TCTCCGAATG TAAATCACCC 
TGCGAGTCGC TGGTTCCCAA GCGTGTCGGT CTCGCTCACA TATCCCAAGT CATTTCGGGA 
GTTGATGGTA ACAGGGTGAC TTTGAGCCAA GAAAACACAC AGGATTCCCT TCCTCTCCAG 
CAGAAGATCT TGGTTTGCTC TTTGCTGCTC TTGACCAAGC GGCTAAAAAT CAAAGAGGTC 
ACCCTGGGGA AGTTATATGA AGCCTACAGT AGTGTCTGTC GTAAACAGCA GGTGGCAGCC 
GTAGACCAGT CTGAGTGTTT GTCCCTTTCT GGACTCCTGG AATCCAGGGG CATTGTGGGA 
CTGAAGAAAA ACAAGGAGAG CCGCCTCACC AAGGTGTCTC TGAAGATTGA AGAAAAGGAG 
ATAGAGCATG TCCTAAAAGG CAAAGCTTTC ATTGGGAACA TCCTCGCTGC CGGGCTGCCC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006247417.1
CDS	286..1968
Translation	MPQTRSQTQATIDFPKKKQSKTLSKTNSRDSEVKLRNVQPVPTTPCADIKILPLSPRKRLGDDNLCNTPHLSPCSPPKLGRKENGPPRSHTRKGCRLIFDDELAVKASAPKEQDRVPQHQILSSAQRGQESETNPEQKCPPEKESACMRLFKQEGTCYQQAKLVLNTAVPDRLPAREQEMGVIRDFLKEHICGKKAGSLYLSGAPGTGKTACLSRILQDFKEVKGFKTIVLNCMSLRNAQAVFPAIAQEIGREELCRPTGKDLMRKLEKHLTAERGPMIVLVLDEMDQLDSKGQDVLYTLFEWPWLSNSRLVLIGIANTLDLTDRILPRLEAREGCKPKLLNFPPYTRNQIAAILQDRLSQVSKDQVLDSAAIQFCARKVSAVSGDIRKALDVCRRAIEIVESDVRSQTVLKPLSECKSPCESLVPKRVGLAHISQVISGVDGNRVTLSQENTQDSLPLQQKILVCSLLLLTKRLKIKEVTLGKLYEAYSSVCRKQQVAAVDQSECLSLSGLLESRGIVGLKKNKESRLTKVSLKIEEKEIEHVLKGKAFIGNILAAGLP

Target ORF information:

RefSeq Version	XM_006247355.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus cell division cycle 6 (Cdc6), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006247355.3

ORF Insert Sequence:

ATGCCTCAAA CCCGATCCCA GACACAAGCT ACCATCGACT TTCCGAAAAA GAAGCAATCT 
AAGACCCTGA GCAAGACAAA CTCCCGTGAC AGTGAAGTAA AACTTAGAAA CGTCCAGCCT 
GTACCCACCA CTCCGTGTGC GGACATAAAA ATTCTGCCTC TCAGTCCCCG AAAACGTTTG 
GGTGATGACA ATCTGTGCAA CACTCCCCAT TTATCTCCAT GTTCTCCGCC CAAGCTGGGC 
AGGAAGGAAA ACGGCCCCCC TCGCTCACAT ACACGGAAGG GATGCAGATT AATATTCGAT 
GATGAGCTGG CAGTTAAGGC TTCCGCCCCA AAAGAACAAG ACAGAGTTCC CCAGCACCAA 
ATACTTTCCT CCGCTCAAAG AGGTCAAGAG AGCGAAACAA ATCCTGAGCA GAAATGCCCA 
CCAGAGAAGG AATCCGCGTG TATGCGACTG TTCAAGCAGG AAGGCACTTG CTATCAACAG 
GCAAAGCTTG TCCTGAATAC AGCTGTCCCG GACCGGCTGC CTGCCAGAGA ACAGGAGATG 
GGTGTCATCA GGGATTTCCT GAAGGAGCAC ATCTGTGGGA AAAAAGCTGG GAGTCTCTAC 
CTTTCTGGCG CTCCTGGAAC TGGGAAAACT GCCTGTTTAA GCCGGATTCT GCAGGACTTC 
AAGGAAGTGA AAGGCTTTAA AACTATCGTG CTGAATTGCA TGTCCCTGAG GAACGCTCAG 
GCCGTGTTCC CAGCCATTGC TCAGGAGATT GGTCGGGAGG AACTCTGCAG ACCCACCGGG 
AAGGACTTGA TGAGAAAGCT GGAAAAGCAC TTGACAGCCG AGAGGGGCCC CATGATTGTG 
TTGGTGTTGG ACGAGATGGA TCAGCTGGAC AGCAAAGGGC AGGATGTGTT ATACACACTG 
TTTGAGTGGC CGTGGTTAAG CAATTCCCGA TTGGTGCTCA TTGGTATTGC TAATACCCTG 
GATCTCACGG ACAGAATTCT GCCGAGACTT GAAGCTAGAG AAGGCTGTAA GCCGAAGCTA 
CTGAACTTCC CACCTTACAC CAGGAATCAG ATAGCTGCGA TCTTGCAGGA TAGGCTTAGT 
CAGGTATCAA AAGACCAGGT TCTGGACAGT GCTGCGATTC AGTTCTGTGC CCGCAAAGTA 
TCTGCTGTCT CAGGGGACAT CCGGAAAGCG CTGGATGTTT GCAGGCGAGC TATTGAAATT 
GTGGAGTCGG ATGTCAGGAG CCAGACAGTC CTCAAACCAC TCTCCGAATG TAAATCACCC 
TGCGAGTCGC TGGTTCCCAA GCGTGTCGGT CTCGCTCACA TATCCCAAGT CATTTCGGGA 
GTTGATGGTA ACAGGGTGAC TTTGAGCCAA GAAAACACAC AGGATTCCCT TCCTCTCCAG 
CAGAAGATCT TGGTTTGCTC TTTGCTGCTC TTGACCAAGC GGCTAAAAAT CAAAGAGGTC 
ACCCTGGGGA AGTTATATGA AGCCTACAGT AGTGTCTGTC GTAAACAGCA GGTGGCAGCC 
GTAGACCAGT CTGAGTGTTT GTCCCTTTCT GGACTCCTGG AATCCAGGGG CATTGTGGGA 
CTGAAGAAAA ACAAGGAGAG CCGCCTCACC AAGGTGTCTC TGAAGATTGA AGAAAAGGAG 
ATAGAGCATG TCCTAAAAGG CAAAGCTTTC ATTGGGAACA TCCTCGCTGC CGGGCTGCCC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Expression of CDc6 after acute spinal cord injury in adult rats.
Neuropeptides5659-67(2016 Apr)
Chen C,Lu J,Yu Q,Xiao JR,Wei HF,Song XJ,Ge JB,Tao WD,Qian R,Yu XW,Zhao J

Recruitment of the human Cdt1 replication licensing protein by the loop domain of Hec1 is required for stable kinetochore-microtubule attachment.
Nature cell biology14(6)593-603(2012 May)
Varma D,Chandrasekaran S,Sundin LJ,Reidy KT,Wan X,Chasse DA,Nevis KR,DeLuca JG,Salmon ED,Cook JG

Cdc6 protein activates p27KIP1-bound Cdk2 protein only after the bound p27 protein undergoes C-terminal phosphorylation.
The Journal of biological chemistry287(9)6275-83(2012 Feb)
Uranbileg B,Yamamoto H,Park JH,Mohanty AR,Arakawa-Takeuchi S,Jinno S,Okayama H

Interactions of MCP1 with components of the replication machinery in mammalian cells.
International journal of biological sciences7(2)193-208(2011 Feb)
Bronze-da-Rocha E,Lin CM,Shimura T,Aladjem MI

Cell division cycle 6, a mitotic substrate of polo-like kinase 1, regulates chromosomal segregation mediated by cyclin-dependent kinase 1 and separase.
Proceedings of the National Academy of Sciences of the United States of America107(46)19742-7(2010 Nov)
Yim H,Erikson RL

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Cdc6 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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