Cyld cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Cyld
Entrez Gene ID	312937
Full Name	CYLD lysine 63 deubiquitinase
Synonyms	LRRGT00003,Rp1,Rp1h
General protein information	Preferred Names CYLD lysine 63 deubiquitinase Names ubiquitin carboxyl-terminal hydrolase CYLD cylindromatosis (turban tumor syndrome) deubiquitinating enzyme CYLD probable ubiquitin carboxyl-terminal hydrolase CYLD probable ubiquitin carboxyl-terminal hydrolase CYLD-like retinitis pigmentosa 1 homolog ubiquitin thioesterase CYLD ubiquitin thiolesterase CYLD ubiquitin-specific-processing protease CYLD
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 19 Map Location: 19p11

mRNA and Protein(s)

mRNA	Protein	Name
NM_001017380.1	NP_001017380.1	ubiquitin carboxyl-terminal hydrolase CYLD

Pathways from BioSystems

Homologies

Gallus gallus (chicken)	CYLD	XP_004944232.1
Drosophila melanogaster (fruit fly)	CYLD	NP_723556.1
Homo sapiens (human)	CYLD	NP_056062.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP008412	XP_317037.4
	CYLD	XP_002802521.1
Mus musculus (house mouse)	Cyld	NP_001121642.1
Pan troglodytes (chimpanzee)	CYLD	XP_001164783.2
Canis lupus familiaris (dog)	CYLD	XP_854436.1
Bos taurus (cattle)	CYLD	NP_001039882.1
Rattus norvegicus (Norway rat)	Cyld	NP_001017380.1
Danio rerio (zebrafish)	cylda	XP_684817.3
Xenopus tropicalis (tropical clawed frog)	cyld	NP_001116960.1

Gene Ontology
Bibliography

Related articles in PubMed

The deubiquitinating enzyme cylindromatosis mitigates nonalcoholic steatohepatitis.
Ji YX, Huang Z, Yang X, Wang X, Zhao LP, Wang PX, Zhang XJ, Alves-Bezerra M, Cai L, Zhang P, Lu YX, Bai L, Gao MM, Zhao H, Tian S, Wang Y, Huang ZX, Zhu XY, Zhang Y, Gong J, She ZG, Li F, Cohen DE, Li H
Nature medicine(2018 Jan)

CYLD Deubiquitinates Nicotinamide Adenine Dinucleotide Phosphate Oxidase 4 Contributing to Adventitial Remodeling.
Yu B, Liu Z, Fu Y, Wang Y, Zhang L, Cai Z, Yu F, Wang X, Zhou J, Kong W
Arteriosclerosis, thrombosis, and vascular biology37(9)1698-1709(2017 Sep)

RNA Interference Reveals the Coregulatory Effects of Cylindromatosis on Apoptosis and Necroptosis of Photoreceptor Cells in Experimental Retinal Detachment.
Dong K, Han L, Liu J, Wang F, Sun X
The American journal of pathology187(8)1763-1771(2017 Aug)

SPATA2 regulates the activation of RIPK1 by modulating linear ubiquitination.
Wei R, Xu LW, Liu J, Li Y, Zhang P, Shan B, Lu X, Qian L, Wu Z, Dong K, Zhu H, Pan L, Yuan J, Pan H
Genes & development31(11)1162-1176(2017 Jun)

SPATA2 Links CYLD to LUBAC, Activates CYLD, and Controls LUBAC Signaling.
Elliott PR, Leske D, Hrdinka M, Bagola K, Fiil BK, McLaughlin SH, Wagstaff J, Volkmar N, Christianson JC, Kessler BM, Freund SM, Komander D, Gyrd-Hansen M
Molecular cell63(6)990-1005(2016 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

CYLD contributes to the transdifferentiation of adventitial fibroblasts via deubiquitinating Nox4 and may play a role in vascular remodeling.
Title: CYLD Deubiquitinates Nicotinamide Adenine Dinucleotide Phosphate Oxidase 4 Contributing to Adventitial Remodeling.

Cylindromatosis coregulates the apoptosis and necroptosis of photoreceptor cells by regulating the ubiquitination of receptor-interacting protein 1 after retinal detachment.
Title: RNA Interference Reveals the Coregulatory Effects of Cylindromatosis on Apoptosis and Necroptosis of Photoreceptor Cells in Experimental Retinal Detachment.

CYLD interrupts the ERK- and p38-/AP-1 and c-Myc pathways to suppress Nrf2-operated antioxidative capacity, thereby enhancing oxidative stress in the heart.
Title: Deubiquitinating enzyme CYLD mediates pressure overload-induced cardiac maladaptive remodeling and dysfunction via downregulating Nrf2.

Altogether, the results suggest that in the absence of excitatory conditions, constitutive IKK activity at the PSD regulates CYLD and maintains basal levels of K63-linkage specific deubiquitination at the synapse.
Title: IKK regulates the deubiquitinase CYLD at the postsynaptic density.

this study investigates the presence of CYLD at postsynaptic density by immunoblotting and immunoEM, and test whether there are changes in PSD-associated CYLD levels following synaptic activity.
Title: CYLD, a deubiquitinase specific for lysine63-linked polyubiquitins, accumulates at the postsynaptic density in an activity-dependent manner.

The following Cyld gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cyld cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa05803	NM_001017380.1 Latest version!	Rattus norvegicus CYLD lysine 63 deubiquitinase (Cyld), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$559.30 $799.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Cyld ( NM_001017380.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001017380.1 Rattus norvegicus CYLD lysine 63 deubiquitinase (Cyld), mRNA.

Price & Availability↑

CloneID	ORa05803
Clone ID Related Accession (Same CDS sequence)	NM_001017380.1
Accession Version	NM_001017380.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2862bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-26
Organism	Rattus norvegicus(Norway rat)
Product	ubiquitin carboxyl-terminal hydrolase CYLD
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC082001.1. On Apr 22, 2005 this sequence version replaced XM_232641.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC082001.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN01906352 [ECO:0000350] ##Evidence-Data-END##

ATGAGTTCAG GCCTGTGGAA CCAAGAGAAA GTTACTTCAC CCTACTGGGA AGAACGGCTT 
TTTTATCTGC TTCTTCAAGA ATGCAGTGTA ACAGACAAAC AGACACAGAA GCTCCTGAGA 
GTACCCAAAG GGAGCATAGG ACAGTACATC CAAGACCGTT CCGTGGGGCA TTCAAGAGTT 
CCTTCTGCTA AAGGCAAGAA AAATCAGATT GGATTAAAAA TCTTAGAGCA ACCGCATGCA 
GTTCTGTTTG TTGATGAAAA GGATGTTGTA GAAATAAATG AAAAATTCAC AGAGTTACTG 
TTGGCAATTA CCAACTGTGA GGAGAGGCTC AGCCTATTTA GAAACAGAAT CCGACTAAGT 
AAAGGCCTCC AGGTAGACGT GGGCAGTCCT GTGAGAGTAC AGCTGCGATC TGGGGAGGAG 
AAGTTTCCAG GAGTTGTACG CTTCAGAGGA CCTTTATTAG CGGAGAGGAC GGTGTCGGGG 
ATTTTCTTTG GAGTAGAATT ACTGGAAGAA GGTCGTGGCC AAGGTTTCAC TGATGGGGTG 
TATCAAGGAA AACAGCTCTT CCAGTGTGAT GAGGACTGTG GCGTTTTTGT TGCATTGGAC 
AAGCTGGAGC TTATAGAAGA TGATGACAAT GGGTTGGAAA GTGATTTTGC AGGCCCAGGA 
GATACAGTCC AGGTTGAACC TCCCCCTTTG GAAATAAACT CCAGAGTTTC TTTGAAGGTT 
GGAGAAAGTA CAGAATCTGG AACAGTGATA TTCTGTGATG TTTTACCAGG AAAAGAGAGT 
CTAGGATATT TTGTTGGTGT GGACATGGAT AACCCTATTG GCAACTGGGA CGGAAGGTTT 
GATGGGGTTC AGCTTTGCAG TTTTGCAAGT GTTGAGAGTA CAGTTCTCCT ACACATCAAT 
GACATCATCC CAGATAGCGT GACACAGGAA AGGAGACCTC CCAAACTTGC CTTTATGTCA 
AGAGGTGTAG GTGACAAAGG TTCATCTAGT CATAATAAAC CAAAGGTTAC AGGATCTACC 
TCAGACCCTG GAAGTAGAAA CAGATCTGAA TTATTTTATA CCTTAAATGG GTCATCTGTT 
GACTCACAAC AACAATCCAA GTCCAAAAAC CCATGGTACA TTGATGAAGT TGCAGAAGAC 
CCTGCAAAGT CACTTACAGA GATGTCTTCA GACTTCGGAC ATTCATCGCC TCCACCGCAA 
CCTCCTTCCA TGAACTCCTT GTCTAGCGAG AACAGATTCC ACTCCTTACC CTTCAGCCTG 
ACAAAGATGC CCAACACTAA TGGCAGCATG GCTCACAGTC CACTCTCTCT GTCAGTGCAG 
TCTGTGATGG GAGAGCTGAA CAGCACTCCT GTCCAGGAGA GTCCACCCAT GCCCAGCTCT 
TCTGGGAATG CACACGGGCT AGAGGTGGGC TCACTGGCTG AAGTAAAAGA GAACCCCCCG 
TTCTATGGGG TTATCCGTTG GATTGGCCAG CCACCAGGGC TCAGTGACGT GCTTGCTGGA 
TTGGAACTGG AAGATGAATG CGCAGGTTGT ACGGATGGAA CTTTCAGGGG CACGCGCTAT 
TTCACCTGTG CCCTGAAGAA AGCACTGTTC GTGAAACTGA AGAGCTGCAG ACCAGACTCT 
AGGTTTGCAT CCTTGCAGCC TGTTTCCAAT CAGATCGAAA GGTGTAACTC TTTAGCATTT 
GGGGGCTACT TAAGTGAAGT AGTAGAAGAA AATACGCCAC CTAAAATGGA AAAGGAAGGT 
TTAGAGATAA TGATTGGAAA GAAGAAAGGC ATCCAGGGCC ATTACAATTC TTGTTACTTA 
GACTCAACTT TATTCTGCTT ATTTGCTTTT AGTTCTGCCC TGGACACTGT ATTACTTAGA 
CCCAAAGAGA AGAATGATGT AGAGTATTAC AGTGAGACTC AAGAGCTACT GAGGACAGAG 
ATAGTCAATC CTCTGAGAAT ATATGGATAT GTGTGTGCCA CAAAGATTAT GAAGCTGAGG 
AAAATACTTG AAAAAGTTGA GGCTGCATCA GGATTTACCT CTGAGGAAAA AGATCCTGAA 
GAATTTCTAA ACATCCTGTT TCATGATATT TTAAGGGTTG AACCATTGTT AAAAATAAGG 
TCAGCAGGTC AAAAAGTTCA AGACTGTAAC TTCTATCAAA TTTTTATGGA AAAAAATGAG 
AAAGTCGGAG TACCCACAAT CCAGCAGTTA TTAGAATGGT CTTTTATCAA CAGCAACCTG 
AAATTTGCAG AGGCACCATC ATGCTTGATT ATCCAGATGC CTCGGTTTGG GAAAGACTTT 
AAACTATTTA AAAAAATTTT TCCTTCCCTG GAATTAAATA TAACAGATTT ACTTGAAGAC 
ACTCCCAGGC AGTGCCGCAT CTGTGGAGGA CTCGCCATGT ATGAGTGTAG AGAGTGCTAT 
GATGACCCGG ACATCTCGGC AGGGAAGATC AAGCAGTTCT GTAAGACCTG CAGCACTCAG 
GTTCACCTTC ATCCCAGAAG ACTGAATCAC ACTTACCATC CAGTATCACT TCCCAAAGAC 
TTGCCCGACT GGGACTGGAG ACACGGCTGC ATCCCGTGTC AGAAGATGGA GTTATTTGCT 
GTGCTCTGCA TAGAAACCAG CCACTATGTT GCTTTTGTGA AGTACGGGAA GGATGACTCT 
GCCTGGCTCT TCTTTGACAG CATGGCTGAT CGAGATGGTG GTCAGAATGG CTTCAACATT 
CCACAAGTGA CACCCTGCCC AGAAGTAGGA GAGTACTTGA AGATGTCTCT GGAGGACCTG 
CACTCTTTGG ACTCCAGAAG GATTCAAGGC TGTGCGCGCA GACTTCTTTG CGATGCATAC 
ATGTGCATGT ACCAGAGTCC AACCATGAGC TTGTACAAAT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001017380.1
CDS	196..3057
Translation	MSSGLWNQEKVTSPYWEERLFYLLLQECSVTDKQTQKLLRVPKGSIGQYIQDRSVGHSRVPSAKGKKNQIGLKILEQPHAVLFVDEKDVVEINEKFTELLLAITNCEERLSLFRNRIRLSKGLQVDVGSPVRVQLRSGEEKFPGVVRFRGPLLAERTVSGIFFGVELLEEGRGQGFTDGVYQGKQLFQCDEDCGVFVALDKLELIEDDDNGLESDFAGPGDTVQVEPPPLEINSRVSLKVGESTESGTVIFCDVLPGKESLGYFVGVDMDNPIGNWDGRFDGVQLCSFASVESTVLLHINDIIPDSVTQERRPPKLAFMSRGVGDKGSSSHNKPKVTGSTSDPGSRNRSELFYTLNGSSVDSQQQSKSKNPWYIDEVAEDPAKSLTEMSSDFGHSSPPPQPPSMNSLSSENRFHSLPFSLTKMPNTNGSMAHSPLSLSVQSVMGELNSTPVQESPPMPSSSGNAHGLEVGSLAEVKENPPFYGVIRWIGQPPGLSDVLAGLELEDECAGCTDGTFRGTRYFTCALKKALFVKLKSCRPDSRFASLQPVSNQIERCNSLAFGGYLSEVVEENTPPKMEKEGLEIMIGKKKGIQGHYNSCYLDSTLFCLFAFSSALDTVLLRPKEKNDVEYYSETQELLRTEIVNPLRIYGYVCATKIMKLRKILEKVEAASGFTSEEKDPEEFLNILFHDILRVEPLLKIRSAGQKVQDCNFYQIFMEKNEKVGVPTIQQLLEWSFINSNLKFAEAPSCLIIQMPRFGKDFKLFKKIFPSLELNITDLLEDTPRQCRICGGLAMYECRECYDDPDISAGKIKQFCKTCSTQVHLHPRRLNHTYHPVSLPKDLPDWDWRHGCIPCQKMELFAVLCIETSHYVAFVKYGKDDSAWLFFDSMADRDGGQNGFNIPQVTPCPEVGEYLKMSLEDLHSLDSRRIQGCARRLLCDAYMCMYQSPTMSLYK

Target ORF information:

RefSeq Version	NM_001017380.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus CYLD lysine 63 deubiquitinase (Cyld), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001017380.1

ORF Insert Sequence:

ATGAGTTCAG GCCTGTGGAA CCAAGAGAAA GTTACTTCAC CCTACTGGGA AGAACGGCTT 
TTTTATCTGC TTCTTCAAGA ATGCAGTGTA ACAGACAAAC AGACACAGAA GCTCCTGAGA 
GTACCCAAAG GGAGCATAGG ACAGTACATC CAAGACCGTT CCGTGGGGCA TTCAAGAGTT 
CCTTCTGCTA AAGGCAAGAA AAATCAGATT GGATTAAAAA TCTTAGAGCA ACCGCATGCA 
GTTCTGTTTG TTGATGAAAA GGATGTTGTA GAAATAAATG AAAAATTCAC AGAGTTACTG 
TTGGCAATTA CCAACTGTGA GGAGAGGCTC AGCCTATTTA GAAACAGAAT CCGACTAAGT 
AAAGGCCTCC AGGTAGACGT GGGCAGTCCT GTGAGAGTAC AGCTGCGATC TGGGGAGGAG 
AAGTTTCCAG GAGTTGTACG CTTCAGAGGA CCTTTATTAG CGGAGAGGAC GGTGTCGGGG 
ATTTTCTTTG GAGTAGAATT ACTGGAAGAA GGTCGTGGCC AAGGTTTCAC TGATGGGGTG 
TATCAAGGAA AACAGCTCTT CCAGTGTGAT GAGGACTGTG GCGTTTTTGT TGCATTGGAC 
AAGCTGGAGC TTATAGAAGA TGATGACAAT GGGTTGGAAA GTGATTTTGC AGGCCCAGGA 
GATACAGTCC AGGTTGAACC TCCCCCTTTG GAAATAAACT CCAGAGTTTC TTTGAAGGTT 
GGAGAAAGTA CAGAATCTGG AACAGTGATA TTCTGTGATG TTTTACCAGG AAAAGAGAGT 
CTAGGATATT TTGTTGGTGT GGACATGGAT AACCCTATTG GCAACTGGGA CGGAAGGTTT 
GATGGGGTTC AGCTTTGCAG TTTTGCAAGT GTTGAGAGTA CAGTTCTCCT ACACATCAAT 
GACATCATCC CAGATAGCGT GACACAGGAA AGGAGACCTC CCAAACTTGC CTTTATGTCA 
AGAGGTGTAG GTGACAAAGG TTCATCTAGT CATAATAAAC CAAAGGTTAC AGGATCTACC 
TCAGACCCTG GAAGTAGAAA CAGATCTGAA TTATTTTATA CCTTAAATGG GTCATCTGTT 
GACTCACAAC AACAATCCAA GTCCAAAAAC CCATGGTACA TTGATGAAGT TGCAGAAGAC 
CCTGCAAAGT CACTTACAGA GATGTCTTCA GACTTCGGAC ATTCATCGCC TCCACCGCAA 
CCTCCTTCCA TGAACTCCTT GTCTAGCGAG AACAGATTCC ACTCCTTACC CTTCAGCCTG 
ACAAAGATGC CCAACACTAA TGGCAGCATG GCTCACAGTC CACTCTCTCT GTCAGTGCAG 
TCTGTGATGG GAGAGCTGAA CAGCACTCCT GTCCAGGAGA GTCCACCCAT GCCCAGCTCT 
TCTGGGAATG CACACGGGCT AGAGGTGGGC TCACTGGCTG AAGTAAAAGA GAACCCCCCG 
TTCTATGGGG TTATCCGTTG GATTGGCCAG CCACCAGGGC TCAGTGACGT GCTTGCTGGA 
TTGGAACTGG AAGATGAATG CGCAGGTTGT ACGGATGGAA CTTTCAGGGG CACGCGCTAT 
TTCACCTGTG CCCTGAAGAA AGCACTGTTC GTGAAACTGA AGAGCTGCAG ACCAGACTCT 
AGGTTTGCAT CCTTGCAGCC TGTTTCCAAT CAGATCGAAA GGTGTAACTC TTTAGCATTT 
GGGGGCTACT TAAGTGAAGT AGTAGAAGAA AATACGCCAC CTAAAATGGA AAAGGAAGGT 
TTAGAGATAA TGATTGGAAA GAAGAAAGGC ATCCAGGGCC ATTACAATTC TTGTTACTTA 
GACTCAACTT TATTCTGCTT ATTTGCTTTT AGTTCTGCCC TGGACACTGT ATTACTTAGA 
CCCAAAGAGA AGAATGATGT AGAGTATTAC AGTGAGACTC AAGAGCTACT GAGGACAGAG 
ATAGTCAATC CTCTGAGAAT ATATGGATAT GTGTGTGCCA CAAAGATTAT GAAGCTGAGG 
AAAATACTTG AAAAAGTTGA GGCTGCATCA GGATTTACCT CTGAGGAAAA AGATCCTGAA 
GAATTTCTAA ACATCCTGTT TCATGATATT TTAAGGGTTG AACCATTGTT AAAAATAAGG 
TCAGCAGGTC AAAAAGTTCA AGACTGTAAC TTCTATCAAA TTTTTATGGA AAAAAATGAG 
AAAGTCGGAG TACCCACAAT CCAGCAGTTA TTAGAATGGT CTTTTATCAA CAGCAACCTG 
AAATTTGCAG AGGCACCATC ATGCTTGATT ATCCAGATGC CTCGGTTTGG GAAAGACTTT 
AAACTATTTA AAAAAATTTT TCCTTCCCTG GAATTAAATA TAACAGATTT ACTTGAAGAC 
ACTCCCAGGC AGTGCCGCAT CTGTGGAGGA CTCGCCATGT ATGAGTGTAG AGAGTGCTAT 
GATGACCCGG ACATCTCGGC AGGGAAGATC AAGCAGTTCT GTAAGACCTG CAGCACTCAG 
GTTCACCTTC ATCCCAGAAG ACTGAATCAC ACTTACCATC CAGTATCACT TCCCAAAGAC 
TTGCCCGACT GGGACTGGAG ACACGGCTGC ATCCCGTGTC AGAAGATGGA GTTATTTGCT 
GTGCTCTGCA TAGAAACCAG CCACTATGTT GCTTTTGTGA AGTACGGGAA GGATGACTCT 
GCCTGGCTCT TCTTTGACAG CATGGCTGAT CGAGATGGTG GTCAGAATGG CTTCAACATT 
CCACAAGTGA CACCCTGCCC AGAAGTAGGA GAGTACTTGA AGATGTCTCT GGAGGACCTG 
CACTCTTTGG ACTCCAGAAG GATTCAAGGC TGTGCGCGCA GACTTCTTTG CGATGCATAC 
ATGTGCATGT ACCAGAGTCC AACCATGAGC TTGTACAAAT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The deubiquitinating enzyme cylindromatosis mitigates nonalcoholic steatohepatitis.
Nature medicine(2018 Jan)
Ji YX,Huang Z,Yang X,Wang X,Zhao LP,Wang PX,Zhang XJ,Alves-Bezerra M,Cai L,Zhang P,Lu YX,Bai L,Gao MM,Zhao H,Tian S,Wang Y,Huang ZX,Zhu XY,Zhang Y,Gong J,She ZG,Li F,Cohen DE,Li H

CYLD Deubiquitinates Nicotinamide Adenine Dinucleotide Phosphate Oxidase 4 Contributing to Adventitial Remodeling.
Arteriosclerosis, thrombosis, and vascular biology37(9)1698-1709(2017 Sep)
Yu B,Liu Z,Fu Y,Wang Y,Zhang L,Cai Z,Yu F,Wang X,Zhou J,Kong W

RNA Interference Reveals the Coregulatory Effects of Cylindromatosis on Apoptosis and Necroptosis of Photoreceptor Cells in Experimental Retinal Detachment.
The American journal of pathology187(8)1763-1771(2017 Aug)
Dong K,Han L,Liu J,Wang F,Sun X

SPATA2 regulates the activation of RIPK1 by modulating linear ubiquitination.
Genes & development31(11)1162-1176(2017 Jun)
Wei R,Xu LW,Liu J,Li Y,Zhang P,Shan B,Lu X,Qian L,Wu Z,Dong K,Zhu H,Pan L,Yuan J,Pan H

SPATA2 Links CYLD to LUBAC, Activates CYLD, and Controls LUBAC Signaling.
Molecular cell63(6)990-1005(2016 Sep)
Elliott PR,Leske D,Hrdinka M,Bagola K,Fiil BK,McLaughlin SH,Wagstaff J,Volkmar N,Christianson JC,Kessler BM,Freund SM,Komander D,Gyrd-Hansen M

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Cyld cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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