Loxl3 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Loxl3
Entrez Gene ID	312478
Full Name	lysyl oxidase-like 3
General protein information	Preferred Names lysyl oxidase-like 3 Names lysyl oxidase homolog 3
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 4 Map Location: 4q34

mRNA and Protein(s)

mRNA	Protein	Name
XM_008763023.2	XP_008761245.1	lysyl oxidase homolog 3 isoform X1
NM_001107866.2	NP_001101336.1	lysyl oxidase homolog 3 precursor

Pathways from BioSystems

Homologies

Homo sapiens (human)	LOXL3	NP_115992.1
Bos taurus (cattle)	LOXL3	NP_001179898.1
Gallus gallus (chicken)	LOXL3	XP_423667.4
Pan troglodytes (chimpanzee)	LOXL3	XP_001161542.1
Canis lupus familiaris (dog)	LOXL3	XP_005630578.1
Danio rerio (zebrafish)	loxl3a	NP_001186799.1
	LOXL3	XP_001110611.1
Mus musculus (house mouse)	Loxl3	NP_038614.2
Rattus norvegicus (Norway rat)	Loxl3	NP_001101336.1

Gene Ontology
Bibliography

Related articles in PubMed

Lysyl Oxidase 3 Is a Dual-Specificity Enzyme Involved in STAT3 Deacetylation and Deacetylimination Modulation.
Ma L, Huang C, Wang XJ, Xin DE, Wang LS, Zou QC, Zhang YS, Tan MD, Wang YM, Zhao TC, Chatterjee D, Altura RA, Wang C, Xu YS, Yang JH, Fan YS, Han BH, Si J, Zhang X, Cheng J, Chang Z, Chin YE
Molecular cell65(2)296-309(2017 Jan)

Loss of Lysyl Oxidase-like 3 Attenuates Embryonic Lung Development in Mice.
Zhang J, Liu Z, Zhang T, Lin Z, Li Z, Zhang A, Sun X, Gao J
Scientific reports633856(2016 Sep)

Localized LoxL3-Dependent Fibronectin Oxidation Regulates Myofiber Stretch and Integrin-Mediated Adhesion.
Kraft-Sheleg O, Zaffryar-Eilot S, Genin O, Yaseen W, Soueid-Baumgarten S, Kessler O, Smolkin T, Akiri G, Neufeld G, Cinnamon Y, Hasson P
Developmental cell36(5)550-61(2016 Mar)

Loss of lysyl oxidase-like 3 causes cleft palate and spinal deformity in mice.
Zhang J, Yang R, Liu Z, Hou C, Zong W, Zhang A, Sun X, Gao J
Human molecular genetics24(21)6174-85(2015 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Loxl3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Loxl3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa34980	NM_001107866.2 Latest version!	Rattus norvegicus lysyl oxidase-like 3 (Loxl3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$440.30 $629.00
ORa47139	XM_008763023.2 Latest version!	Rattus norvegicus lysyl oxidase-like 3 (Loxl3), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Loxl3 ( NM_001107866.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001101336.1 Rattus norvegicus lysyl oxidase-like 3 (Loxl3), mRNA.

Price & Availability↑

CloneID	ORa34980
Clone ID Related Accession (Same CDS sequence)	NM_001107866.2
Accession Version	NM_001107866.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2265bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-03-24
Organism	Rattus norvegicus(Norway rat)
Product	lysyl oxidase homolog 3 precursor
Comment	Comment: INFERRED REFSEQ: This record is predicted by genome sequence analysis and is not yet supported by experimental evidence. The reference sequence was derived from AC130866.5. On Oct 12, 2007 this sequence version replaced NM_001107866.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGAGAGCTG TCAATGTGTG CTATTGCTGC CCGTGGCGAC TACTGCTGCT GCACTTTCTG 
TGCAGCTCCA GTATGGGGTC TCCGTCTCCT TCTACCGACC CAGAGAAGAA GGTAGGAAGC 
CAGGGGCTGA GGTTCCGTCT GGCTGGCTTT CCTAGAAAGC CCTATGAGGG CCGTGTGGAG 
ATACAGCGAG CCGGCGAATG GGGCACCATC TGTGATGATG ACTTCACGCT GCAGGCTGCC 
CACGTCCTCT GCCGGGAGCT GGGCTTCACA GAAGCCACCG GTTGGACCCA CAGTGCCAAA 
TACGGCCCAG GAACAGGCCG AATCTGGTTG GACAATCTGA GCTGCAAGGG TACTGAAGGA 
AGTGTGACTG AATGTGCCTC CCGGGGCTGG GGAAACAGTG ACTGTACCCA TGACGAGGAT 
GCTGGGGTCA TCTGCAAGGA CCAGCGCCTT CCCGGTTTCT CAGACTCCAA CGTCATTGAG 
GTGGATCATC AGCTCCAAGT GGAGGAAGTG CGACTCCGAC CAGCTGTGGA GTGGGGCAGG 
CGACCCCTGC CTGTGACTGA GGGCCTGGTT GAAGTCAGGC TTCCTGAAGG CTGGTCGCAA 
GTGTGTGACA AAGGCTGGAG TGCCCACAAC AGCCACGTAG TCTGCGGTAT GCTGGGTTTC 
CCTGGAGAAA AGAGAGTCAA CATGGCCTTC TACAGGATGC TGGCCCAGAA GAAGCAACAC 
TCCTTTGGTC TACACAGCGT GGCATGTGTG GGCACAGAAG CCCACCTCTC CCTTTGCTCT 
CTGGAGTTCT ATCGTGCCAA TGACACCACC AGATGTGCTG GTGGGAGCCC TGCAGTGGTG 
AGCTGTATGC TGGGCCCTCT TTATGCCACC TCTACTGGTC AGAAGAAGCA GCAACATTCT 
AAGCCTCAAG GGGAGGCCAG TGTGCGTCTA AAGGGCGGTG CCCACCCTGG AGAAGGCCGA 
GTGGAAGTCC TGAAGGCTGG CACATGGGGA ACAGTCTGTG ACCGAAAGTG GGATCTGCAG 
GCAGCCAGTG TAGTGTGTCG AGAGCTGGGC TTTGGCACTG CCCGAGAAGC CCTGAGTGGT 
GCCCGCATGG GGCAGGGCAT GGGTGCCATC CACTTGAGTG AAGTTCGGTG CTCTGGCCAG 
GAACCCTCCC TTTGGAAATG CCCCTCTAAG AACATCACAG CTGAGGACTG TTCCCATAGC 
CAGGATGCAG CTGTCCGGTG CAACCTCCCC TACACTGGGG TGGAGACCAA GATCCGACTC 
AGTGGGGGCC GCAGTCGATA CGAAGGGCGA GTCGAGGTGC AAATAGGGGT ACCTGGGCAT 
CTACGCTGGG GCCTCATCTG TGGGGATGAC TGGGGAACAC TGGAGGCCAT GGTGGCCTGT 
AGGCAACTTG GTCTTGGCTA CGCCAACCAC GGCCTGCAGG AGACCTGGTA CTGGGACTCG 
GGGAATGTAA CTGAGGTGGT GATGAGCGGA GTACGTTGCA CAGGGTCTGA GCTGTCCCTG 
AACCAATGTG CTCACCACAA CACCCACGTC ACCTGCAAGA GGACAGGCAC CCGCTTCACT 
GCAGGAGTCA TCTGTTCTGA GACTGCTTCG GATCTGCTGC TGCACTCAGC ACTGGTACAG 
GAGACTGCTT ATATTGAAGA CCGACCGTTG CACATGTTGT ACTGTGCTGC TGAAGAGAAC 
TGCCTGGCAA GCTCCGCCCG CTCAGCTAAC TGGCCCTACG GCCACAGGCG TCTGCTCCGA 
TTCTCTTCCC AGATCCACAA CCTAGGAAGA GCTGACTTTA GGCCCAAGGC TGGGCGCCAT 
TCCTGGGTGT GGCATGAGTG TCACGGGCAT TACCACAGCA TGGACATCTT CACTCATTAT 
GATATCCTGA CCCCCAACGG CACCAAGGTG GCTGAGGGCC ACAAAGCTAG TTTCTGTCTA 
GAAGACACTG AGTGTCAGGA GGATGTCTCC AAGAGATATG AGTGTGCCAA CTTTGGAGAG 
CAGGGCATCA CTGTGGGATG CTGGGACCTC TACAGGCATG ACATTGACTG TCAGTGGATT 
GACATCACAG ATGTGAAACC AGGAAACTAC ATTCTTCAGG TGGTTATCAA CCCAAATTTT 
GAGGTAGCAG AAAGTGACTT CACCAACAAT GCTATGAAGT GCAACTGCAA ATACGACGGG 
CATCGCATCT GGGTGCACAA CTGCCACATT GGTGATGCCT TCAGTGAAGA AGCCAACAGG 
AGGTTTGAGC GCTACCCAGG CCAGACCAGT AACCAGATTG TCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001101336.1
CDS	144..2408
Translation	MRAVNVCYCCPWRLLLLHFLCSSSMGSPSPSTDPEKKVGSQGLRFRLAGFPRKPYEGRVEIQRAGEWGTICDDDFTLQAAHVLCRELGFTEATGWTHSAKYGPGTGRIWLDNLSCKGTEGSVTECASRGWGNSDCTHDEDAGVICKDQRLPGFSDSNVIEVDHQLQVEEVRLRPAVEWGRRPLPVTEGLVEVRLPEGWSQVCDKGWSAHNSHVVCGMLGFPGEKRVNMAFYRMLAQKKQHSFGLHSVACVGTEAHLSLCSLEFYRANDTTRCAGGSPAVVSCMLGPLYATSTGQKKQQHSKPQGEASVRLKGGAHPGEGRVEVLKAGTWGTVCDRKWDLQAASVVCRELGFGTAREALSGARMGQGMGAIHLSEVRCSGQEPSLWKCPSKNITAEDCSHSQDAAVRCNLPYTGVETKIRLSGGRSRYEGRVEVQIGVPGHLRWGLICGDDWGTLEAMVACRQLGLGYANHGLQETWYWDSGNVTEVVMSGVRCTGSELSLNQCAHHNTHVTCKRTGTRFTAGVICSETASDLLLHSALVQETAYIEDRPLHMLYCAAEENCLASSARSANWPYGHRRLLRFSSQIHNLGRADFRPKAGRHSWVWHECHGHYHSMDIFTHYDILTPNGTKVAEGHKASFCLEDTECQEDVSKRYECANFGEQGITVGCWDLYRHDIDCQWIDITDVKPGNYILQVVINPNFEVAESDFTNNAMKCNCKYDGHRIWVHNCHIGDAFSEEANRRFERYPGQTSNQIV

Target ORF information:

RefSeq Version	NM_001107866.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus lysyl oxidase-like 3 (Loxl3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001107866.2

ORF Insert Sequence:

ATGAGAGCTG TCAATGTGTG CTATTGCTGC CCGTGGCGAC TACTGCTGCT GCACTTTCTG 
TGCAGCTCCA GTATGGGGTC TCCGTCTCCT TCTACCGACC CAGAGAAGAA GGTAGGAAGC 
CAGGGGCTGA GGTTCCGTCT GGCTGGCTTT CCTAGAAAGC CCTATGAGGG CCGTGTGGAG 
ATACAGCGAG CCGGCGAATG GGGCACCATC TGTGATGATG ACTTCACGCT GCAGGCTGCC 
CACGTCCTCT GCCGGGAGCT GGGCTTCACA GAAGCCACCG GTTGGACCCA CAGTGCCAAA 
TACGGCCCAG GAACAGGCCG AATCTGGTTG GACAATCTGA GCTGCAAGGG TACTGAAGGA 
AGTGTGACTG AATGTGCCTC CCGGGGCTGG GGAAACAGTG ACTGTACCCA TGACGAGGAT 
GCTGGGGTCA TCTGCAAGGA CCAGCGCCTT CCCGGTTTCT CAGACTCCAA CGTCATTGAG 
GTGGATCATC AGCTCCAAGT GGAGGAAGTG CGACTCCGAC CAGCTGTGGA GTGGGGCAGG 
CGACCCCTGC CTGTGACTGA GGGCCTGGTT GAAGTCAGGC TTCCTGAAGG CTGGTCGCAA 
GTGTGTGACA AAGGCTGGAG TGCCCACAAC AGCCACGTAG TCTGCGGTAT GCTGGGTTTC 
CCTGGAGAAA AGAGAGTCAA CATGGCCTTC TACAGGATGC TGGCCCAGAA GAAGCAACAC 
TCCTTTGGTC TACACAGCGT GGCATGTGTG GGCACAGAAG CCCACCTCTC CCTTTGCTCT 
CTGGAGTTCT ATCGTGCCAA TGACACCACC AGATGTGCTG GTGGGAGCCC TGCAGTGGTG 
AGCTGTATGC TGGGCCCTCT TTATGCCACC TCTACTGGTC AGAAGAAGCA GCAACATTCT 
AAGCCTCAAG GGGAGGCCAG TGTGCGTCTA AAGGGCGGTG CCCACCCTGG AGAAGGCCGA 
GTGGAAGTCC TGAAGGCTGG CACATGGGGA ACAGTCTGTG ACCGAAAGTG GGATCTGCAG 
GCAGCCAGTG TAGTGTGTCG AGAGCTGGGC TTTGGCACTG CCCGAGAAGC CCTGAGTGGT 
GCCCGCATGG GGCAGGGCAT GGGTGCCATC CACTTGAGTG AAGTTCGGTG CTCTGGCCAG 
GAACCCTCCC TTTGGAAATG CCCCTCTAAG AACATCACAG CTGAGGACTG TTCCCATAGC 
CAGGATGCAG CTGTCCGGTG CAACCTCCCC TACACTGGGG TGGAGACCAA GATCCGACTC 
AGTGGGGGCC GCAGTCGATA CGAAGGGCGA GTCGAGGTGC AAATAGGGGT ACCTGGGCAT 
CTACGCTGGG GCCTCATCTG TGGGGATGAC TGGGGAACAC TGGAGGCCAT GGTGGCCTGT 
AGGCAACTTG GTCTTGGCTA CGCCAACCAC GGCCTGCAGG AGACCTGGTA CTGGGACTCG 
GGGAATGTAA CTGAGGTGGT GATGAGCGGA GTACGTTGCA CAGGGTCTGA GCTGTCCCTG 
AACCAATGTG CTCACCACAA CACCCACGTC ACCTGCAAGA GGACAGGCAC CCGCTTCACT 
GCAGGAGTCA TCTGTTCTGA GACTGCTTCG GATCTGCTGC TGCACTCAGC ACTGGTACAG 
GAGACTGCTT ATATTGAAGA CCGACCGTTG CACATGTTGT ACTGTGCTGC TGAAGAGAAC 
TGCCTGGCAA GCTCCGCCCG CTCAGCTAAC TGGCCCTACG GCCACAGGCG TCTGCTCCGA 
TTCTCTTCCC AGATCCACAA CCTAGGAAGA GCTGACTTTA GGCCCAAGGC TGGGCGCCAT 
TCCTGGGTGT GGCATGAGTG TCACGGGCAT TACCACAGCA TGGACATCTT CACTCATTAT 
GATATCCTGA CCCCCAACGG CACCAAGGTG GCTGAGGGCC ACAAAGCTAG TTTCTGTCTA 
GAAGACACTG AGTGTCAGGA GGATGTCTCC AAGAGATATG AGTGTGCCAA CTTTGGAGAG 
CAGGGCATCA CTGTGGGATG CTGGGACCTC TACAGGCATG ACATTGACTG TCAGTGGATT 
GACATCACAG ATGTGAAACC AGGAAACTAC ATTCTTCAGG TGGTTATCAA CCCAAATTTT 
GAGGTAGCAG AAAGTGACTT CACCAACAAT GCTATGAAGT GCAACTGCAA ATACGACGGG 
CATCGCATCT GGGTGCACAA CTGCCACATT GGTGATGCCT TCAGTGAAGA AGCCAACAGG 
AGGTTTGAGC GCTACCCAGG CCAGACCAGT AACCAGATTG TCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Loxl3 ( XM_008763023.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008761245.1 Rattus norvegicus lysyl oxidase-like 3 (Loxl3), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa47139
Clone ID Related Accession (Same CDS sequence)	XM_008763023.2
Accession Version	XM_008763023.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2382bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	lysyl oxidase homolog 3 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005103.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008763023.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGAGCTG TCAATGTGTG CTATTGCTGC CCGTGGCGAC TACTGCTGCT GCACTTTCTG 
TGCAGCTCCA GTATGGGGTC TCCGTCTCCT TCTACCGACC CAGAGAAGAA GGTAGGAAGC 
CAGGGGCTGA GGTTCCGTCT GGCTGGCTTT CCTAGAAAGC CCTATGAGGG CCGTGTGGAG 
ATACAGCGAG CCGGCGAATG GGGCACCATC TGTGATGATG ACTTCACGCT GCAGGCTGCC 
CACGTCCTCT GCCGGGAGCT GGGCTTCACA GAAGCCACCG GTTGGACCCA CAGTGCCAAA 
TACGGCCCAG GAACAGGCCG AATCTGGTTG GACAATCTGA GCTGCAAGGG TACTGAAGGA 
AGTGTGACTG AATGTGCCTC CCGGGGCTGG GGAAACAGTG ACTGTACCCA TGACGAGGAT 
GCTGGGGTCA TCTGCAAGGA CCAGCGCCTT CCCGGTTTCT CAGACTCCAA CGTCATTGAG 
GTGGATCATC AGCTCCAAGT GGAGGAAGTG CGACTCCGAC CAGCTGTGGA GTGGGGCAGG 
CGACCCCTGC CTGTGACTGA GGGCCTGGTT GAAGTCAGGC TTCCTGAAGG CTGGTCGCAA 
GTGTGTGACA AAGGCTGGAG TGCCCACAAC AGCCACGTAG TCTGCGGTAT GCTGGGTTTC 
CCTGGAGAAA AGAGAGTCAA CATGGCCTTC TACAGAAAGT TGAGGAAGCG AGCAGCCAAA 
GCCTCAGCCC GACACCCCAA GTCCCCTGGA AGAACAATCA ACAAGTTTAA AGTCAAACAC 
AAGCCCCAAT TGGGCAGAGG GCCAAGTAAG AGGATGCTGG CCCAGAAGAA GCAACACTCC 
TTTGGTCTAC ACAGCGTGGC ATGTGTGGGC ACAGAAGCCC ACCTCTCCCT TTGCTCTCTG 
GAGTTCTATC GTGCCAATGA CACCACCAGA TGTGCTGGTG GGAGCCCTGC AGTGGTGAGC 
TGTATGCTGG GCCCTCTTTA TGCCACCTCT ACTGGTCAGA AGAAGCAGCA ACATTCTAAG 
CCTCAAGGGG AGGCCAGTGT GCGTCTAAAG GGCGGTGCCC ACCCTGGAGA AGGCCGAGTG 
GAAGTCCTGA AGGCTGGCAC ATGGGGAACA GTCTGTGACC GAAAGTGGGA TCTGCAGGCA 
GCCAGTGTAG TGTGTCGAGA GCTGGGCTTT GGCACTGCCC GAGAAGCCCT GAGTGGTGCC 
CGCATGGGGC AGGGCATGGG TGCCATCCAC TTGAGTGAAG TTCGGTGCTC TGGCCAGGAA 
CCCTCCCTTT GGAAATGCCC CTCTAAGAAC ATCACAGCTG AGGACTGTTC CCATAGCCAG 
GATGCAGCTG TCCGGTGCAA CCTCCCCTAC ACTGGGGTGG AGACCAAGAT CCGACTCAGT 
GGGGGCCGCA GTCGATACGA AGGGCGAGTC GAGGTGCAAA TAGGGGTACC TGGGCATCTA 
CGCTGGGGCC TCATCTGTGG GGATGACTGG GGAACACTGG AGGCCATGGT GGCCTGTAGG 
CAACTTGGTC TTGGCTACGC CAACCACGGC CTGCAGGAGA CCTGGTACTG GGACTCGGGG 
AATGTAACTG AGGTGGTGAT GAGCGGAGTA CGTTGCACAG GGTCTGAGCT GTCCCTGAAC 
CAATGTGCTC ACCACAACAC CCACGTCACC TGCAAGAGGA CAGGCACCCG CTTCACTGCA 
GGAGTCATCT GTTCTGAGAC TGCTTCGGAT CTGCTGCTGC ACTCAGCACT GGTACAGGAG 
ACTGCTTATA TTGAAGACCG ACCGTTGCAC ATGTTGTACT GTGCTGCTGA AGAGAACTGC 
CTGGCAAGCT CCGCCCGCTC AGCTAACTGG CCCTACGGCC ACAGGCGTCT GCTCCGATTC 
TCTTCCCAGA TCCACAACCT AGGAAGAGCT GACTTTAGGC CCAAGGCTGG GCGCCATTCC 
TGGGTGTGGC ATGAGTGTCA CGGGCATTAC CACAGCATGG ACATCTTCAC TCATTATGAT 
ATCCTGACCC CCAACGGCAC CAAGGTGGCT GAGGGCCACA AAGCTAGTTT CTGTCTAGAA 
GACACTGAGT GTCAGGAGGA TGTCTCCAAG AGATATGAGT GTGCCAACTT TGGAGAGCAG 
GGCATCACTG TGGGATGCTG GGACCTCTAC AGGCATGACA TTGACTGTCA GTGGATTGAC 
ATCACAGATG TGAAACCAGG AAACTACATT CTTCAGGTGG TTATCAACCC AAATTTTGAG 
GTAGCAGAAA GTGACTTCAC CAACAATGCT ATGAAGTGCA ACTGCAAATA CGACGGGCAT 
CGCATCTGGG TGCACAACTG CCACATTGGT GATGCCTTCA GTGAAGAAGC CAACAGGAGG 
TTTGAGCGCT ACCCAGGCCA GACCAGTAAC CAGATTGTCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008761245.1
CDS	760..3141
Translation	MRAVNVCYCCPWRLLLLHFLCSSSMGSPSPSTDPEKKVGSQGLRFRLAGFPRKPYEGRVEIQRAGEWGTICDDDFTLQAAHVLCRELGFTEATGWTHSAKYGPGTGRIWLDNLSCKGTEGSVTECASRGWGNSDCTHDEDAGVICKDQRLPGFSDSNVIEVDHQLQVEEVRLRPAVEWGRRPLPVTEGLVEVRLPEGWSQVCDKGWSAHNSHVVCGMLGFPGEKRVNMAFYRKLRKRAAKASARHPKSPGRTINKFKVKHKPQLGRGPSKRMLAQKKQHSFGLHSVACVGTEAHLSLCSLEFYRANDTTRCAGGSPAVVSCMLGPLYATSTGQKKQQHSKPQGEASVRLKGGAHPGEGRVEVLKAGTWGTVCDRKWDLQAASVVCRELGFGTAREALSGARMGQGMGAIHLSEVRCSGQEPSLWKCPSKNITAEDCSHSQDAAVRCNLPYTGVETKIRLSGGRSRYEGRVEVQIGVPGHLRWGLICGDDWGTLEAMVACRQLGLGYANHGLQETWYWDSGNVTEVVMSGVRCTGSELSLNQCAHHNTHVTCKRTGTRFTAGVICSETASDLLLHSALVQETAYIEDRPLHMLYCAAEENCLASSARSANWPYGHRRLLRFSSQIHNLGRADFRPKAGRHSWVWHECHGHYHSMDIFTHYDILTPNGTKVAEGHKASFCLEDTECQEDVSKRYECANFGEQGITVGCWDLYRHDIDCQWIDITDVKPGNYILQVVINPNFEVAESDFTNNAMKCNCKYDGHRIWVHNCHIGDAFSEEANRRFERYPGQTSNQIV

Target ORF information:

RefSeq Version	XM_008763023.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus lysyl oxidase-like 3 (Loxl3), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008763023.2

ORF Insert Sequence:

ATGAGAGCTG TCAATGTGTG CTATTGCTGC CCGTGGCGAC TACTGCTGCT GCACTTTCTG 
TGCAGCTCCA GTATGGGGTC TCCGTCTCCT TCTACCGACC CAGAGAAGAA GGTAGGAAGC 
CAGGGGCTGA GGTTCCGTCT GGCTGGCTTT CCTAGAAAGC CCTATGAGGG CCGTGTGGAG 
ATACAGCGAG CCGGCGAATG GGGCACCATC TGTGATGATG ACTTCACGCT GCAGGCTGCC 
CACGTCCTCT GCCGGGAGCT GGGCTTCACA GAAGCCACCG GTTGGACCCA CAGTGCCAAA 
TACGGCCCAG GAACAGGCCG AATCTGGTTG GACAATCTGA GCTGCAAGGG TACTGAAGGA 
AGTGTGACTG AATGTGCCTC CCGGGGCTGG GGAAACAGTG ACTGTACCCA TGACGAGGAT 
GCTGGGGTCA TCTGCAAGGA CCAGCGCCTT CCCGGTTTCT CAGACTCCAA CGTCATTGAG 
GTGGATCATC AGCTCCAAGT GGAGGAAGTG CGACTCCGAC CAGCTGTGGA GTGGGGCAGG 
CGACCCCTGC CTGTGACTGA GGGCCTGGTT GAAGTCAGGC TTCCTGAAGG CTGGTCGCAA 
GTGTGTGACA AAGGCTGGAG TGCCCACAAC AGCCACGTAG TCTGCGGTAT GCTGGGTTTC 
CCTGGAGAAA AGAGAGTCAA CATGGCCTTC TACAGAAAGT TGAGGAAGCG AGCAGCCAAA 
GCCTCAGCCC GACACCCCAA GTCCCCTGGA AGAACAATCA ACAAGTTTAA AGTCAAACAC 
AAGCCCCAAT TGGGCAGAGG GCCAAGTAAG AGGATGCTGG CCCAGAAGAA GCAACACTCC 
TTTGGTCTAC ACAGCGTGGC ATGTGTGGGC ACAGAAGCCC ACCTCTCCCT TTGCTCTCTG 
GAGTTCTATC GTGCCAATGA CACCACCAGA TGTGCTGGTG GGAGCCCTGC AGTGGTGAGC 
TGTATGCTGG GCCCTCTTTA TGCCACCTCT ACTGGTCAGA AGAAGCAGCA ACATTCTAAG 
CCTCAAGGGG AGGCCAGTGT GCGTCTAAAG GGCGGTGCCC ACCCTGGAGA AGGCCGAGTG 
GAAGTCCTGA AGGCTGGCAC ATGGGGAACA GTCTGTGACC GAAAGTGGGA TCTGCAGGCA 
GCCAGTGTAG TGTGTCGAGA GCTGGGCTTT GGCACTGCCC GAGAAGCCCT GAGTGGTGCC 
CGCATGGGGC AGGGCATGGG TGCCATCCAC TTGAGTGAAG TTCGGTGCTC TGGCCAGGAA 
CCCTCCCTTT GGAAATGCCC CTCTAAGAAC ATCACAGCTG AGGACTGTTC CCATAGCCAG 
GATGCAGCTG TCCGGTGCAA CCTCCCCTAC ACTGGGGTGG AGACCAAGAT CCGACTCAGT 
GGGGGCCGCA GTCGATACGA AGGGCGAGTC GAGGTGCAAA TAGGGGTACC TGGGCATCTA 
CGCTGGGGCC TCATCTGTGG GGATGACTGG GGAACACTGG AGGCCATGGT GGCCTGTAGG 
CAACTTGGTC TTGGCTACGC CAACCACGGC CTGCAGGAGA CCTGGTACTG GGACTCGGGG 
AATGTAACTG AGGTGGTGAT GAGCGGAGTA CGTTGCACAG GGTCTGAGCT GTCCCTGAAC 
CAATGTGCTC ACCACAACAC CCACGTCACC TGCAAGAGGA CAGGCACCCG CTTCACTGCA 
GGAGTCATCT GTTCTGAGAC TGCTTCGGAT CTGCTGCTGC ACTCAGCACT GGTACAGGAG 
ACTGCTTATA TTGAAGACCG ACCGTTGCAC ATGTTGTACT GTGCTGCTGA AGAGAACTGC 
CTGGCAAGCT CCGCCCGCTC AGCTAACTGG CCCTACGGCC ACAGGCGTCT GCTCCGATTC 
TCTTCCCAGA TCCACAACCT AGGAAGAGCT GACTTTAGGC CCAAGGCTGG GCGCCATTCC 
TGGGTGTGGC ATGAGTGTCA CGGGCATTAC CACAGCATGG ACATCTTCAC TCATTATGAT 
ATCCTGACCC CCAACGGCAC CAAGGTGGCT GAGGGCCACA AAGCTAGTTT CTGTCTAGAA 
GACACTGAGT GTCAGGAGGA TGTCTCCAAG AGATATGAGT GTGCCAACTT TGGAGAGCAG 
GGCATCACTG TGGGATGCTG GGACCTCTAC AGGCATGACA TTGACTGTCA GTGGATTGAC 
ATCACAGATG TGAAACCAGG AAACTACATT CTTCAGGTGG TTATCAACCC AAATTTTGAG 
GTAGCAGAAA GTGACTTCAC CAACAATGCT ATGAAGTGCA ACTGCAAATA CGACGGGCAT 
CGCATCTGGG TGCACAACTG CCACATTGGT GATGCCTTCA GTGAAGAAGC CAACAGGAGG 
TTTGAGCGCT ACCCAGGCCA GACCAGTAAC CAGATTGTCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Lysyl Oxidase 3 Is a Dual-Specificity Enzyme Involved in STAT3 Deacetylation and Deacetylimination Modulation.
Molecular cell65(2)296-309(2017 Jan)
Ma L,Huang C,Wang XJ,Xin DE,Wang LS,Zou QC,Zhang YS,Tan MD,Wang YM,Zhao TC,Chatterjee D,Altura RA,Wang C,Xu YS,Yang JH,Fan YS,Han BH,Si J,Zhang X,Cheng J,Chang Z,Chin YE

Loss of Lysyl Oxidase-like 3 Attenuates Embryonic Lung Development in Mice.
Scientific reports633856(2016 Sep)
Zhang J,Liu Z,Zhang T,Lin Z,Li Z,Zhang A,Sun X,Gao J

Localized LoxL3-Dependent Fibronectin Oxidation Regulates Myofiber Stretch and Integrin-Mediated Adhesion.
Developmental cell36(5)550-61(2016 Mar)
Kraft-Sheleg O,Zaffryar-Eilot S,Genin O,Yaseen W,Soueid-Baumgarten S,Kessler O,Smolkin T,Akiri G,Neufeld G,Cinnamon Y,Hasson P

Loss of lysyl oxidase-like 3 causes cleft palate and spinal deformity in mice.
Human molecular genetics24(21)6174-85(2015 Nov)
Zhang J,Yang R,Liu Z,Hou C,Zong W,Zhang A,Sun X,Gao J

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Loxl3 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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