Itgb6 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Itgb6
Entrez Gene ID	311061
Full Name	integrin beta 6
General protein information	Preferred Names integrin beta 6 Names integrin beta-6 integrin subunit beta 6
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 3 Map Location: 3q21
Summary	mouse homolog is involved in TGF-beta activation and regulation of macrophage metalloproteinase Mmp12 expression [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_006234233.3	XP_006234295.1	integrin beta-6 isoform X1
XM_008761846.2	XP_008760068.1	integrin beta-6 isoform X2
NM_001004263.1	NP_001004263.1	integrin beta-6 precursor
XM_006234232.2	XP_006234294.1	integrin beta-6 isoform X1
XM_008761845.2	XP_008760067.1	integrin beta-6 isoform X2
XM_017591686.1	XP_017447175.1	integrin beta-6 isoform X2

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	ITGB6	XP_001149234.1
Bos taurus (cattle)	ITGB6	NP_777123.1
Homo sapiens (human)	ITGB6	NP_001269282.1
Gallus gallus (chicken)	ITGB6	XP_004942881.1
Danio rerio (zebrafish)	itgb6	XP_003199474.1
	ITGB6	XP_001094740.2
Mus musculus (house mouse)	Itgb6	NP_001153036.1
Xenopus tropicalis (tropical clawed frog)	itgb6	NP_001090775.1
Canis lupus familiaris (dog)	ITGB6	XP_005640289.1
Rattus norvegicus (Norway rat)	Itgb6	NP_001004263.1

Gene Ontology
Bibliography

Related articles in PubMed

Interleukin-1? Promotes Epithelial-Derived Alveolar Elastogenesis via ?v?6 Integrin-Dependent TGF-? Activation.
Wang J, Bao L, Yu B, Liu Z, Han W, Deng C, Guo C
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology36(6)2198-216(2015)

Kindlin-1 controls Wnt and TGF-? availability to regulate cutaneous stem cell proliferation.
Rognoni E, Widmaier M, Jakobson M, Ruppert R, Ussar S, Katsougkri D, B?ttcher RT, Lai-Cheong JE, Rifkin DB, McGrath JA, F?ssler R
Nature medicine20(4)350-9(2014 Apr)

Role of integrin ?v?6 in the pathogenesis of ischemia-related biliary fibrosis after liver transplantation.
Chen G, Zhang L, Chen L, Wang H, Zhang Y, Bie P
Transplantation95(9)1092-9(2013 May)

Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.
Ghai R, Bugarcic A, Liu H, Norwood SJ, Skeldal S, Coulson EJ, Li SS, Teasdale RD, Collins BM
Proceedings of the National Academy of Sciences of the United States of America110(8)E643-52(2013 Feb)

Lysophosphatidic acid increases proximal tubule cell secretion of profibrotic cytokines PDGF-B and CTGF through LPA2- and G?q-mediated Rho and ?v?6 integrin-dependent activation of TGF-?.
Geng H, Lan R, Singha PK, Gilchrist A, Weinreb PH, Violette SM, Weinberg JM, Saikumar P, Venkatachalam MA
The American journal of pathology181(4)1236-49(2012 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

These data support the hypothesis that IL-1beta was initially induced by hyperoxia; alphavbeta6 subsequently interacted with and activated TGF-beta1.
Title: Interleukin-1? Promotes Epithelial-Derived Alveolar Elastogenesis via ?v?6 Integrin-Dependent TGF-? Activation.

Integrin alphavbeta6 is strongly induced de novo in newly formed bile ducts because of cholangiocyte proliferation during ischemia-related biliary fibrogenesis after liver transplantation.
Title: Role of integrin ?v?6 in the pathogenesis of ischemia-related biliary fibrosis after liver transplantation.

Lysophosphatidic acid signals through LPA2 receptors and Galphaq proteins of cultured proximal tubule cells to transactivate latent TGF-beta in a Rho/Rho-kinase and alphavbeta6 integrin-dependent manner.
Title: Lysophosphatidic acid increases proximal tubule cell secretion of profibrotic cytokines PDGF-B and CTGF through LPA2- and G?q-mediated Rho and ?v?6 integrin-dependent activation of TGF-?.

Integrin alphavbeta6 is strongly up-regulated in proliferating bile duct epithelia and drives fibrogenesis via adhesion to fibronectin and auto/paracrine TGF-beta1 activation.
Title: Inhibition of integrin alphavbeta6 on cholangiocytes blocks transforming growth factor-beta activation and retards biliary fibrosis progression.

Integrin alphavbeta6 is induced de novo in rodent and human liver fibrosis, where it is expressed on activated bile duct epithelia and (transitional) hepatocytes during fibrosis progression.
Title: Integrin alphavbeta6 is a marker of the progression of biliary and portal liver fibrosis and a novel target for antifibrotic therapies.

The following Itgb6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Itgb6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa10289	NM_001004263.1 Latest version!	Rattus norvegicus integrin subunit beta 6 (Itgb6), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
ORa10289	XM_006234232.2 Latest version!	Rattus norvegicus integrin subunit beta 6 (Itgb6), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
ORa10289	XM_006234233.3 Latest version!	Rattus norvegicus integrin subunit beta 6 (Itgb6), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
ORa46938	XM_008761845.2 Latest version!	Rattus norvegicus integrin subunit beta 6 (Itgb6), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
ORa46938	XM_017591686.1 Latest version!	Rattus norvegicus integrin subunit beta 6 (Itgb6), transcript variant X5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
ORa46938	XM_008761846.2 Latest version!	Rattus norvegicus integrin subunit beta 6 (Itgb6), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Itgb6 ( NM_001004263.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001004263.1 Rattus norvegicus integrin subunit beta 6 (Itgb6), mRNA.

Price & Availability↑

CloneID	ORa10289
Clone ID Related Accession (Same CDS sequence)	XM_006234233.3 , NM_001004263.1 , XM_006234232.2
Accession Version	NM_001004263.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2364bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-26
Organism	Rattus norvegicus(Norway rat)
Product	integrin beta-6 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC079069.1. On Sep 10, 2004 this sequence version replaced XM_229949.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC079069.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGGGGATTG AGCTGGTCTG CCTGTTCCTG CTACTTCTAG GAAGGAATGA TCACGTCCAA 
GGTGGCTGTG CCTGGAGTGG TGCAGAAACC TGCTCAGACT GCCTGCTCAC AGGACCTCAC 
TGCGCCTGGT GCTCCCAGGA GAATTTCACC CACCTGTCCG GAGCTGGCGA AAGGTGCGAC 
ACCCCCGAGA ATCTTTTAGC CAAAGGATGT CAGTTACCCT TCATCGAAAA CCCTGTCTCC 
CAAGTAGAAA TACTTCAAAA TAAGCCTCTC AGCGTAGGTC GACAGAAAAA CAGTTCTGAC 
ATTGTTCAGA TTGCTCCTCA AAGCTTGGTT CTTAAGTTGA GACCAGGGGG TGAGCAGACT 
CTGCAAGTGC AGGTCCGCCA GACGGAAGAT TACCCAGTAG ATCTGTATTA CCTCATGGAC 
CTCTCGGCCT CCATGGATGA TGACCTCAAC ACAATCAAAG AGCTTGGCTC CCGGCTGGCC 
AAAGAGATGT CTAAATTAAC CAGCAACTTT AGACTGGGCT TTGGCTCTTT TGTGGAAAAG 
CCCGTTTCTC CTTTTATGAA AACAACACCA GAGGAAATCA CCAACCCTTG CAGTAGTATC 
CCCTATTTCT GCTTACCTAC ATTTGGATTC AAGCACATTT TGCCATTGAC TGATGATGCT 
GAGAGATTCA ATGAAATTGT GAGGAAACAG AAGATTTCCG CTAATATTGA CACGCCTGAA 
GGCGGATTCG ATGCCATCAT GCAAGCTGCT GTGTGTAAGG AAAAGATTGG CTGGCGCAAC 
GACTCGCTCC ACCTCCTGGT TTTTGTGAGT GATGCTGATT CTCATTTTGG AATGGACAGC 
AAGCTGGCAG GCATTGTGAT TCCCAACGAT GGGCTCTGTC ACTTGGACAA CAGGAATGAA 
TACTCCATGT CAACTGTCTT GGAATATCCA ACGATCGGCC AACTCATTGA TAAACTGGTA 
CAAAACAACG TGCTACTGAT CTTTGCGGTC ACCCAAGAAC AAGTCCATCT CTATGAGAAT 
TATGCGAAAC TCATCCCTGG AGCGACTGTG GGACTGCTTC AGAAGGATTC TGGGAACATT 
CTTCAGCTGA TCATCTCCGC TTACGAAGAA CTGCGGTCTG AGGTGGAACT AGAAGTATTA 
GGAGACACAG AAGGACTCAA CCTGTCTTTC ACAGCTCTCT GTAGCAATGG CATCCTCTTC 
CCACACCAAA AGAAGTGTTC CCACATGAAA GTCGGAGATA CAGCATCCTT CAACGTGTCT 
GTGAGCATAA CAAACTGTGA GAAAAGAAGC AGGAAACTTA TCATCAAGCC TGTGGGACTT 
GGGGACACCC TGGAAATACT CGTCAGCGCA GAATGTGACT GCGACTGCCA GAGAGAAGTA 
GAAGCCAACA GTTCTAAGTG CCACCACGGG AATGGCTCCT TCCAGTGTGG GGTGTGTGCC 
TGCAACCCTG GCCACATGGG TCCTCGCTGC GAGTGCGGCG AGGACATGGT GAGCACGGAT 
TCCTGCAAGG AGTCCCCAGG TCACCCCTCC TGCAGCGGAA GGGGTGACTG CTATTGTGGG 
CAGTGTGTCT GCCACTTGTC TCCCTATGGA AGCATCTATG GACCTTACTG CCAGTGTGAC 
AACTTCTCCT GTCTGAGACA CAAAGGCCTG CTCTGTGGAG ATAATGGTGA CTGTGACTGT 
GGTGAATGCG TGTGCCGGGA TGGCTGGACG GGCGAGTACT GCAACTGTAC AACCAGCAGG 
GATGCGTGTG CATCGGAAGA TGGCGTGCTG TGCAGCGGGC GTGGGGACTG TGTCTGCGGC 
AAGTGTGTCT GCAGAAACCC TGGAGCCTCG GGACCCACCT GTGAACGCTG CCCTACCTGT 
GGAGACCCCT GTAACTCGAG ACGGAGCTGC ATCGAGTGCT ACCTGTCTGC AGATGGCCAG 
GCCCAAGAAG AGTGCGAGGA CAAGTGCAAA GCCACCGGTG CCACCATCAG TGAGGAAGAG 
TTTTCAAAGG ATACTTCTGT CCCCTGCTCG CTACAAGGAG AAAATGAATG TCTTATTACA 
TTCCTAATAA CTGCGGATAA TGAAGGGAAA ACCATCATTC ACAACATCAG TGAAAAAGAC 
TGCCCCAAAC CTCCAAACAT TCCCATGATC ATGTTGGGGG TGTCACTGGC TATCCTGCTC 
ATCGGTGTCG TGCTACTGTG CATTTGGAAG CTGCTGGTAT CCTTTCACGA CCGGAAAGAA 
GTTGCTAAAT TTGAAGCAGA ACGATCAAAG GCCAAGTGGC AAACGGGAAC CAATCCGCTG 
TACCGAGGCT CCACCAGCAC TTTTAAGAAC GTGACCTACA AACACAGGGA GAAGCACAAA 
GTGGGCCTTT CTTCAGATGG GTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001004263.1
CDS	67..2430
Translation	MGIELVCLFLLLLGRNDHVQGGCAWSGAETCSDCLLTGPHCAWCSQENFTHLSGAGERCDTPENLLAKGCQLPFIENPVSQVEILQNKPLSVGRQKNSSDIVQIAPQSLVLKLRPGGEQTLQVQVRQTEDYPVDLYYLMDLSASMDDDLNTIKELGSRLAKEMSKLTSNFRLGFGSFVEKPVSPFMKTTPEEITNPCSSIPYFCLPTFGFKHILPLTDDAERFNEIVRKQKISANIDTPEGGFDAIMQAAVCKEKIGWRNDSLHLLVFVSDADSHFGMDSKLAGIVIPNDGLCHLDNRNEYSMSTVLEYPTIGQLIDKLVQNNVLLIFAVTQEQVHLYENYAKLIPGATVGLLQKDSGNILQLIISAYEELRSEVELEVLGDTEGLNLSFTALCSNGILFPHQKKCSHMKVGDTASFNVSVSITNCEKRSRKLIIKPVGLGDTLEILVSAECDCDCQREVEANSSKCHHGNGSFQCGVCACNPGHMGPRCECGEDMVSTDSCKESPGHPSCSGRGDCYCGQCVCHLSPYGSIYGPYCQCDNFSCLRHKGLLCGDNGDCDCGECVCRDGWTGEYCNCTTSRDACASEDGVLCSGRGDCVCGKCVCRNPGASGPTCERCPTCGDPCNSRRSCIECYLSADGQAQEECEDKCKATGATISEEEFSKDTSVPCSLQGENECLITFLITADNEGKTIIHNISEKDCPKPPNIPMIMLGVSLAILLIGVVLLCIWKLLVSFHDRKEVAKFEAERSKAKWQTGTNPLYRGSTSTFKNVTYKHREKHKVGLSSDG

Target ORF information:

RefSeq Version	NM_001004263.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus integrin subunit beta 6 (Itgb6), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001004263.1

ORF Insert Sequence:

ATGGGGATTG AGCTGGTCTG CCTGTTCCTG CTACTTCTAG GAAGGAATGA TCACGTCCAA 
GGTGGCTGTG CCTGGAGTGG TGCAGAAACC TGCTCAGACT GCCTGCTCAC AGGACCTCAC 
TGCGCCTGGT GCTCCCAGGA GAATTTCACC CACCTGTCCG GAGCTGGCGA AAGGTGCGAC 
ACCCCCGAGA ATCTTTTAGC CAAAGGATGT CAGTTACCCT TCATCGAAAA CCCTGTCTCC 
CAAGTAGAAA TACTTCAAAA TAAGCCTCTC AGCGTAGGTC GACAGAAAAA CAGTTCTGAC 
ATTGTTCAGA TTGCTCCTCA AAGCTTGGTT CTTAAGTTGA GACCAGGGGG TGAGCAGACT 
CTGCAAGTGC AGGTCCGCCA GACGGAAGAT TACCCAGTAG ATCTGTATTA CCTCATGGAC 
CTCTCGGCCT CCATGGATGA TGACCTCAAC ACAATCAAAG AGCTTGGCTC CCGGCTGGCC 
AAAGAGATGT CTAAATTAAC CAGCAACTTT AGACTGGGCT TTGGCTCTTT TGTGGAAAAG 
CCCGTTTCTC CTTTTATGAA AACAACACCA GAGGAAATCA CCAACCCTTG CAGTAGTATC 
CCCTATTTCT GCTTACCTAC ATTTGGATTC AAGCACATTT TGCCATTGAC TGATGATGCT 
GAGAGATTCA ATGAAATTGT GAGGAAACAG AAGATTTCCG CTAATATTGA CACGCCTGAA 
GGCGGATTCG ATGCCATCAT GCAAGCTGCT GTGTGTAAGG AAAAGATTGG CTGGCGCAAC 
GACTCGCTCC ACCTCCTGGT TTTTGTGAGT GATGCTGATT CTCATTTTGG AATGGACAGC 
AAGCTGGCAG GCATTGTGAT TCCCAACGAT GGGCTCTGTC ACTTGGACAA CAGGAATGAA 
TACTCCATGT CAACTGTCTT GGAATATCCA ACGATCGGCC AACTCATTGA TAAACTGGTA 
CAAAACAACG TGCTACTGAT CTTTGCGGTC ACCCAAGAAC AAGTCCATCT CTATGAGAAT 
TATGCGAAAC TCATCCCTGG AGCGACTGTG GGACTGCTTC AGAAGGATTC TGGGAACATT 
CTTCAGCTGA TCATCTCCGC TTACGAAGAA CTGCGGTCTG AGGTGGAACT AGAAGTATTA 
GGAGACACAG AAGGACTCAA CCTGTCTTTC ACAGCTCTCT GTAGCAATGG CATCCTCTTC 
CCACACCAAA AGAAGTGTTC CCACATGAAA GTCGGAGATA CAGCATCCTT CAACGTGTCT 
GTGAGCATAA CAAACTGTGA GAAAAGAAGC AGGAAACTTA TCATCAAGCC TGTGGGACTT 
GGGGACACCC TGGAAATACT CGTCAGCGCA GAATGTGACT GCGACTGCCA GAGAGAAGTA 
GAAGCCAACA GTTCTAAGTG CCACCACGGG AATGGCTCCT TCCAGTGTGG GGTGTGTGCC 
TGCAACCCTG GCCACATGGG TCCTCGCTGC GAGTGCGGCG AGGACATGGT GAGCACGGAT 
TCCTGCAAGG AGTCCCCAGG TCACCCCTCC TGCAGCGGAA GGGGTGACTG CTATTGTGGG 
CAGTGTGTCT GCCACTTGTC TCCCTATGGA AGCATCTATG GACCTTACTG CCAGTGTGAC 
AACTTCTCCT GTCTGAGACA CAAAGGCCTG CTCTGTGGAG ATAATGGTGA CTGTGACTGT 
GGTGAATGCG TGTGCCGGGA TGGCTGGACG GGCGAGTACT GCAACTGTAC AACCAGCAGG 
GATGCGTGTG CATCGGAAGA TGGCGTGCTG TGCAGCGGGC GTGGGGACTG TGTCTGCGGC 
AAGTGTGTCT GCAGAAACCC TGGAGCCTCG GGACCCACCT GTGAACGCTG CCCTACCTGT 
GGAGACCCCT GTAACTCGAG ACGGAGCTGC ATCGAGTGCT ACCTGTCTGC AGATGGCCAG 
GCCCAAGAAG AGTGCGAGGA CAAGTGCAAA GCCACCGGTG CCACCATCAG TGAGGAAGAG 
TTTTCAAAGG ATACTTCTGT CCCCTGCTCG CTACAAGGAG AAAATGAATG TCTTATTACA 
TTCCTAATAA CTGCGGATAA TGAAGGGAAA ACCATCATTC ACAACATCAG TGAAAAAGAC 
TGCCCCAAAC CTCCAAACAT TCCCATGATC ATGTTGGGGG TGTCACTGGC TATCCTGCTC 
ATCGGTGTCG TGCTACTGTG CATTTGGAAG CTGCTGGTAT CCTTTCACGA CCGGAAAGAA 
GTTGCTAAAT TTGAAGCAGA ACGATCAAAG GCCAAGTGGC AAACGGGAAC CAATCCGCTG 
TACCGAGGCT CCACCAGCAC TTTTAAGAAC GTGACCTACA AACACAGGGA GAAGCACAAA 
GTGGGCCTTT CTTCAGATGG GTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Itgb6 ( XM_006234233.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006234295.1 Rattus norvegicus integrin subunit beta 6 (Itgb6), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa10289
Clone ID Related Accession (Same CDS sequence)	XM_006234233.3 , NM_001004263.1 , XM_006234232.2
Accession Version	XM_006234233.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2364bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	integrin beta-6 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005102.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006234233.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGGATTG AGCTGGTCTG CCTGTTCCTG CTACTTCTAG GAAGGAATGA TCACGTCCAA 
GGTGGCTGTG CCTGGAGTGG TGCAGAAACC TGCTCAGACT GCCTGCTCAC AGGACCTCAC 
TGCGCCTGGT GCTCCCAGGA GAATTTCACC CACCTGTCCG GAGCTGGCGA AAGGTGCGAC 
ACCCCCGAGA ATCTTTTAGC CAAAGGATGT CAGTTACCCT TCATCGAAAA CCCTGTCTCC 
CAAGTAGAAA TACTTCAAAA TAAGCCTCTC AGCGTAGGTC GACAGAAAAA CAGTTCTGAC 
ATTGTTCAGA TTGCTCCTCA AAGCTTGGTT CTTAAGTTGA GACCAGGGGG TGAGCAGACT 
CTGCAAGTGC AGGTCCGCCA GACGGAAGAT TACCCAGTAG ATCTGTATTA CCTCATGGAC 
CTCTCGGCCT CCATGGATGA TGACCTCAAC ACAATCAAAG AGCTTGGCTC CCGGCTGGCC 
AAAGAGATGT CTAAATTAAC CAGCAACTTT AGACTGGGCT TTGGCTCTTT TGTGGAAAAG 
CCCGTTTCTC CTTTTATGAA AACAACACCA GAGGAAATCA CCAACCCTTG CAGTAGTATC 
CCCTATTTCT GCTTACCTAC ATTTGGATTC AAGCACATTT TGCCATTGAC TGATGATGCT 
GAGAGATTCA ATGAAATTGT GAGGAAACAG AAGATTTCCG CTAATATTGA CACGCCTGAA 
GGCGGATTCG ATGCCATCAT GCAAGCTGCT GTGTGTAAGG AAAAGATTGG CTGGCGCAAC 
GACTCGCTCC ACCTCCTGGT TTTTGTGAGT GATGCTGATT CTCATTTTGG AATGGACAGC 
AAGCTGGCAG GCATTGTGAT TCCCAACGAT GGGCTCTGTC ACTTGGACAA CAGGAATGAA 
TACTCCATGT CAACTGTCTT GGAATATCCA ACGATCGGCC AACTCATTGA TAAACTGGTA 
CAAAACAACG TGCTACTGAT CTTTGCGGTC ACCCAAGAAC AAGTCCATCT CTATGAGAAT 
TATGCGAAAC TCATCCCTGG AGCGACTGTG GGACTGCTTC AGAAGGATTC TGGGAACATT 
CTTCAGCTGA TCATCTCCGC TTACGAAGAA CTGCGGTCTG AGGTGGAACT AGAAGTATTA 
GGAGACACAG AAGGACTCAA CCTGTCTTTC ACAGCTCTCT GTAGCAATGG CATCCTCTTC 
CCACACCAAA AGAAGTGTTC CCACATGAAA GTCGGAGATA CAGCATCCTT CAACGTGTCT 
GTGAGCATAA CAAACTGTGA GAAAAGAAGC AGGAAACTTA TCATCAAGCC TGTGGGACTT 
GGGGACACCC TGGAAATACT CGTCAGCGCA GAATGTGACT GCGACTGCCA GAGAGAAGTA 
GAAGCCAACA GTTCTAAGTG CCACCACGGG AATGGCTCCT TCCAGTGTGG GGTGTGTGCC 
TGCAACCCTG GCCACATGGG TCCTCGCTGC GAGTGCGGCG AGGACATGGT GAGCACGGAT 
TCCTGCAAGG AGTCCCCAGG TCACCCCTCC TGCAGCGGAA GGGGTGACTG CTATTGTGGG 
CAGTGTGTCT GCCACTTGTC TCCCTATGGA AGCATCTATG GACCTTACTG CCAGTGTGAC 
AACTTCTCCT GTCTGAGACA CAAAGGCCTG CTCTGTGGAG ATAATGGTGA CTGTGACTGT 
GGTGAATGCG TGTGCCGGGA TGGCTGGACG GGCGAGTACT GCAACTGTAC AACCAGCAGG 
GATGCGTGTG CATCGGAAGA TGGCGTGCTG TGCAGCGGGC GTGGGGACTG TGTCTGCGGC 
AAGTGTGTCT GCAGAAACCC TGGAGCCTCG GGACCCACCT GTGAACGCTG CCCTACCTGT 
GGAGACCCCT GTAACTCGAG ACGGAGCTGC ATCGAGTGCT ACCTGTCTGC AGATGGCCAG 
GCCCAAGAAG AGTGCGAGGA CAAGTGCAAA GCCACCGGTG CCACCATCAG TGAGGAAGAG 
TTTTCAAAGG ATACTTCTGT CCCCTGCTCG CTACAAGGAG AAAATGAATG TCTTATTACA 
TTCCTAATAA CTGCGGATAA TGAAGGGAAA ACCATCATTC ACAACATCAG TGAAAAAGAC 
TGCCCCAAAC CTCCAAACAT TCCCATGATC ATGTTGGGGG TGTCACTGGC TATCCTGCTC 
ATCGGTGTCG TGCTACTGTG CATTTGGAAG CTGCTGGTAT CCTTTCACGA CCGGAAAGAA 
GTTGCTAAAT TTGAAGCAGA ACGATCAAAG GCCAAGTGGC AAACGGGAAC CAATCCGCTG 
TACCGAGGCT CCACCAGCAC TTTTAAGAAC GTGACCTACA AACACAGGGA GAAGCACAAA 
GTGGGCCTTT CTTCAGATGG GTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006234295.1
CDS	314..2677
Translation	MGIELVCLFLLLLGRNDHVQGGCAWSGAETCSDCLLTGPHCAWCSQENFTHLSGAGERCDTPENLLAKGCQLPFIENPVSQVEILQNKPLSVGRQKNSSDIVQIAPQSLVLKLRPGGEQTLQVQVRQTEDYPVDLYYLMDLSASMDDDLNTIKELGSRLAKEMSKLTSNFRLGFGSFVEKPVSPFMKTTPEEITNPCSSIPYFCLPTFGFKHILPLTDDAERFNEIVRKQKISANIDTPEGGFDAIMQAAVCKEKIGWRNDSLHLLVFVSDADSHFGMDSKLAGIVIPNDGLCHLDNRNEYSMSTVLEYPTIGQLIDKLVQNNVLLIFAVTQEQVHLYENYAKLIPGATVGLLQKDSGNILQLIISAYEELRSEVELEVLGDTEGLNLSFTALCSNGILFPHQKKCSHMKVGDTASFNVSVSITNCEKRSRKLIIKPVGLGDTLEILVSAECDCDCQREVEANSSKCHHGNGSFQCGVCACNPGHMGPRCECGEDMVSTDSCKESPGHPSCSGRGDCYCGQCVCHLSPYGSIYGPYCQCDNFSCLRHKGLLCGDNGDCDCGECVCRDGWTGEYCNCTTSRDACASEDGVLCSGRGDCVCGKCVCRNPGASGPTCERCPTCGDPCNSRRSCIECYLSADGQAQEECEDKCKATGATISEEEFSKDTSVPCSLQGENECLITFLITADNEGKTIIHNISEKDCPKPPNIPMIMLGVSLAILLIGVVLLCIWKLLVSFHDRKEVAKFEAERSKAKWQTGTNPLYRGSTSTFKNVTYKHREKHKVGLSSDG

Target ORF information:

RefSeq Version	XM_006234233.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus integrin subunit beta 6 (Itgb6), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006234233.3

ORF Insert Sequence:

ATGGGGATTG AGCTGGTCTG CCTGTTCCTG CTACTTCTAG GAAGGAATGA TCACGTCCAA 
GGTGGCTGTG CCTGGAGTGG TGCAGAAACC TGCTCAGACT GCCTGCTCAC AGGACCTCAC 
TGCGCCTGGT GCTCCCAGGA GAATTTCACC CACCTGTCCG GAGCTGGCGA AAGGTGCGAC 
ACCCCCGAGA ATCTTTTAGC CAAAGGATGT CAGTTACCCT TCATCGAAAA CCCTGTCTCC 
CAAGTAGAAA TACTTCAAAA TAAGCCTCTC AGCGTAGGTC GACAGAAAAA CAGTTCTGAC 
ATTGTTCAGA TTGCTCCTCA AAGCTTGGTT CTTAAGTTGA GACCAGGGGG TGAGCAGACT 
CTGCAAGTGC AGGTCCGCCA GACGGAAGAT TACCCAGTAG ATCTGTATTA CCTCATGGAC 
CTCTCGGCCT CCATGGATGA TGACCTCAAC ACAATCAAAG AGCTTGGCTC CCGGCTGGCC 
AAAGAGATGT CTAAATTAAC CAGCAACTTT AGACTGGGCT TTGGCTCTTT TGTGGAAAAG 
CCCGTTTCTC CTTTTATGAA AACAACACCA GAGGAAATCA CCAACCCTTG CAGTAGTATC 
CCCTATTTCT GCTTACCTAC ATTTGGATTC AAGCACATTT TGCCATTGAC TGATGATGCT 
GAGAGATTCA ATGAAATTGT GAGGAAACAG AAGATTTCCG CTAATATTGA CACGCCTGAA 
GGCGGATTCG ATGCCATCAT GCAAGCTGCT GTGTGTAAGG AAAAGATTGG CTGGCGCAAC 
GACTCGCTCC ACCTCCTGGT TTTTGTGAGT GATGCTGATT CTCATTTTGG AATGGACAGC 
AAGCTGGCAG GCATTGTGAT TCCCAACGAT GGGCTCTGTC ACTTGGACAA CAGGAATGAA 
TACTCCATGT CAACTGTCTT GGAATATCCA ACGATCGGCC AACTCATTGA TAAACTGGTA 
CAAAACAACG TGCTACTGAT CTTTGCGGTC ACCCAAGAAC AAGTCCATCT CTATGAGAAT 
TATGCGAAAC TCATCCCTGG AGCGACTGTG GGACTGCTTC AGAAGGATTC TGGGAACATT 
CTTCAGCTGA TCATCTCCGC TTACGAAGAA CTGCGGTCTG AGGTGGAACT AGAAGTATTA 
GGAGACACAG AAGGACTCAA CCTGTCTTTC ACAGCTCTCT GTAGCAATGG CATCCTCTTC 
CCACACCAAA AGAAGTGTTC CCACATGAAA GTCGGAGATA CAGCATCCTT CAACGTGTCT 
GTGAGCATAA CAAACTGTGA GAAAAGAAGC AGGAAACTTA TCATCAAGCC TGTGGGACTT 
GGGGACACCC TGGAAATACT CGTCAGCGCA GAATGTGACT GCGACTGCCA GAGAGAAGTA 
GAAGCCAACA GTTCTAAGTG CCACCACGGG AATGGCTCCT TCCAGTGTGG GGTGTGTGCC 
TGCAACCCTG GCCACATGGG TCCTCGCTGC GAGTGCGGCG AGGACATGGT GAGCACGGAT 
TCCTGCAAGG AGTCCCCAGG TCACCCCTCC TGCAGCGGAA GGGGTGACTG CTATTGTGGG 
CAGTGTGTCT GCCACTTGTC TCCCTATGGA AGCATCTATG GACCTTACTG CCAGTGTGAC 
AACTTCTCCT GTCTGAGACA CAAAGGCCTG CTCTGTGGAG ATAATGGTGA CTGTGACTGT 
GGTGAATGCG TGTGCCGGGA TGGCTGGACG GGCGAGTACT GCAACTGTAC AACCAGCAGG 
GATGCGTGTG CATCGGAAGA TGGCGTGCTG TGCAGCGGGC GTGGGGACTG TGTCTGCGGC 
AAGTGTGTCT GCAGAAACCC TGGAGCCTCG GGACCCACCT GTGAACGCTG CCCTACCTGT 
GGAGACCCCT GTAACTCGAG ACGGAGCTGC ATCGAGTGCT ACCTGTCTGC AGATGGCCAG 
GCCCAAGAAG AGTGCGAGGA CAAGTGCAAA GCCACCGGTG CCACCATCAG TGAGGAAGAG 
TTTTCAAAGG ATACTTCTGT CCCCTGCTCG CTACAAGGAG AAAATGAATG TCTTATTACA 
TTCCTAATAA CTGCGGATAA TGAAGGGAAA ACCATCATTC ACAACATCAG TGAAAAAGAC 
TGCCCCAAAC CTCCAAACAT TCCCATGATC ATGTTGGGGG TGTCACTGGC TATCCTGCTC 
ATCGGTGTCG TGCTACTGTG CATTTGGAAG CTGCTGGTAT CCTTTCACGA CCGGAAAGAA 
GTTGCTAAAT TTGAAGCAGA ACGATCAAAG GCCAAGTGGC AAACGGGAAC CAATCCGCTG 
TACCGAGGCT CCACCAGCAC TTTTAAGAAC GTGACCTACA AACACAGGGA GAAGCACAAA 
GTGGGCCTTT CTTCAGATGG GTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Itgb6 ( XM_006234232.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006234294.1 Rattus norvegicus integrin subunit beta 6 (Itgb6), transcript variant X1, mRNA.

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CloneID	ORa10289
Clone ID Related Accession (Same CDS sequence)	XM_006234233.3 , NM_001004263.1 , XM_006234232.2
Accession Version	XM_006234232.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2364bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	integrin beta-6 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005102.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006234232.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGGATTG AGCTGGTCTG CCTGTTCCTG CTACTTCTAG GAAGGAATGA TCACGTCCAA 
GGTGGCTGTG CCTGGAGTGG TGCAGAAACC TGCTCAGACT GCCTGCTCAC AGGACCTCAC 
TGCGCCTGGT GCTCCCAGGA GAATTTCACC CACCTGTCCG GAGCTGGCGA AAGGTGCGAC 
ACCCCCGAGA ATCTTTTAGC CAAAGGATGT CAGTTACCCT TCATCGAAAA CCCTGTCTCC 
CAAGTAGAAA TACTTCAAAA TAAGCCTCTC AGCGTAGGTC GACAGAAAAA CAGTTCTGAC 
ATTGTTCAGA TTGCTCCTCA AAGCTTGGTT CTTAAGTTGA GACCAGGGGG TGAGCAGACT 
CTGCAAGTGC AGGTCCGCCA GACGGAAGAT TACCCAGTAG ATCTGTATTA CCTCATGGAC 
CTCTCGGCCT CCATGGATGA TGACCTCAAC ACAATCAAAG AGCTTGGCTC CCGGCTGGCC 
AAAGAGATGT CTAAATTAAC CAGCAACTTT AGACTGGGCT TTGGCTCTTT TGTGGAAAAG 
CCCGTTTCTC CTTTTATGAA AACAACACCA GAGGAAATCA CCAACCCTTG CAGTAGTATC 
CCCTATTTCT GCTTACCTAC ATTTGGATTC AAGCACATTT TGCCATTGAC TGATGATGCT 
GAGAGATTCA ATGAAATTGT GAGGAAACAG AAGATTTCCG CTAATATTGA CACGCCTGAA 
GGCGGATTCG ATGCCATCAT GCAAGCTGCT GTGTGTAAGG AAAAGATTGG CTGGCGCAAC 
GACTCGCTCC ACCTCCTGGT TTTTGTGAGT GATGCTGATT CTCATTTTGG AATGGACAGC 
AAGCTGGCAG GCATTGTGAT TCCCAACGAT GGGCTCTGTC ACTTGGACAA CAGGAATGAA 
TACTCCATGT CAACTGTCTT GGAATATCCA ACGATCGGCC AACTCATTGA TAAACTGGTA 
CAAAACAACG TGCTACTGAT CTTTGCGGTC ACCCAAGAAC AAGTCCATCT CTATGAGAAT 
TATGCGAAAC TCATCCCTGG AGCGACTGTG GGACTGCTTC AGAAGGATTC TGGGAACATT 
CTTCAGCTGA TCATCTCCGC TTACGAAGAA CTGCGGTCTG AGGTGGAACT AGAAGTATTA 
GGAGACACAG AAGGACTCAA CCTGTCTTTC ACAGCTCTCT GTAGCAATGG CATCCTCTTC 
CCACACCAAA AGAAGTGTTC CCACATGAAA GTCGGAGATA CAGCATCCTT CAACGTGTCT 
GTGAGCATAA CAAACTGTGA GAAAAGAAGC AGGAAACTTA TCATCAAGCC TGTGGGACTT 
GGGGACACCC TGGAAATACT CGTCAGCGCA GAATGTGACT GCGACTGCCA GAGAGAAGTA 
GAAGCCAACA GTTCTAAGTG CCACCACGGG AATGGCTCCT TCCAGTGTGG GGTGTGTGCC 
TGCAACCCTG GCCACATGGG TCCTCGCTGC GAGTGCGGCG AGGACATGGT GAGCACGGAT 
TCCTGCAAGG AGTCCCCAGG TCACCCCTCC TGCAGCGGAA GGGGTGACTG CTATTGTGGG 
CAGTGTGTCT GCCACTTGTC TCCCTATGGA AGCATCTATG GACCTTACTG CCAGTGTGAC 
AACTTCTCCT GTCTGAGACA CAAAGGCCTG CTCTGTGGAG ATAATGGTGA CTGTGACTGT 
GGTGAATGCG TGTGCCGGGA TGGCTGGACG GGCGAGTACT GCAACTGTAC AACCAGCAGG 
GATGCGTGTG CATCGGAAGA TGGCGTGCTG TGCAGCGGGC GTGGGGACTG TGTCTGCGGC 
AAGTGTGTCT GCAGAAACCC TGGAGCCTCG GGACCCACCT GTGAACGCTG CCCTACCTGT 
GGAGACCCCT GTAACTCGAG ACGGAGCTGC ATCGAGTGCT ACCTGTCTGC AGATGGCCAG 
GCCCAAGAAG AGTGCGAGGA CAAGTGCAAA GCCACCGGTG CCACCATCAG TGAGGAAGAG 
TTTTCAAAGG ATACTTCTGT CCCCTGCTCG CTACAAGGAG AAAATGAATG TCTTATTACA 
TTCCTAATAA CTGCGGATAA TGAAGGGAAA ACCATCATTC ACAACATCAG TGAAAAAGAC 
TGCCCCAAAC CTCCAAACAT TCCCATGATC ATGTTGGGGG TGTCACTGGC TATCCTGCTC 
ATCGGTGTCG TGCTACTGTG CATTTGGAAG CTGCTGGTAT CCTTTCACGA CCGGAAAGAA 
GTTGCTAAAT TTGAAGCAGA ACGATCAAAG GCCAAGTGGC AAACGGGAAC CAATCCGCTG 
TACCGAGGCT CCACCAGCAC TTTTAAGAAC GTGACCTACA AACACAGGGA GAAGCACAAA 
GTGGGCCTTT CTTCAGATGG GTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006234294.1
CDS	409..2772
Translation	MGIELVCLFLLLLGRNDHVQGGCAWSGAETCSDCLLTGPHCAWCSQENFTHLSGAGERCDTPENLLAKGCQLPFIENPVSQVEILQNKPLSVGRQKNSSDIVQIAPQSLVLKLRPGGEQTLQVQVRQTEDYPVDLYYLMDLSASMDDDLNTIKELGSRLAKEMSKLTSNFRLGFGSFVEKPVSPFMKTTPEEITNPCSSIPYFCLPTFGFKHILPLTDDAERFNEIVRKQKISANIDTPEGGFDAIMQAAVCKEKIGWRNDSLHLLVFVSDADSHFGMDSKLAGIVIPNDGLCHLDNRNEYSMSTVLEYPTIGQLIDKLVQNNVLLIFAVTQEQVHLYENYAKLIPGATVGLLQKDSGNILQLIISAYEELRSEVELEVLGDTEGLNLSFTALCSNGILFPHQKKCSHMKVGDTASFNVSVSITNCEKRSRKLIIKPVGLGDTLEILVSAECDCDCQREVEANSSKCHHGNGSFQCGVCACNPGHMGPRCECGEDMVSTDSCKESPGHPSCSGRGDCYCGQCVCHLSPYGSIYGPYCQCDNFSCLRHKGLLCGDNGDCDCGECVCRDGWTGEYCNCTTSRDACASEDGVLCSGRGDCVCGKCVCRNPGASGPTCERCPTCGDPCNSRRSCIECYLSADGQAQEECEDKCKATGATISEEEFSKDTSVPCSLQGENECLITFLITADNEGKTIIHNISEKDCPKPPNIPMIMLGVSLAILLIGVVLLCIWKLLVSFHDRKEVAKFEAERSKAKWQTGTNPLYRGSTSTFKNVTYKHREKHKVGLSSDG

Target ORF information:

RefSeq Version	XM_006234232.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus integrin subunit beta 6 (Itgb6), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006234232.2

ORF Insert Sequence:

ATGGGGATTG AGCTGGTCTG CCTGTTCCTG CTACTTCTAG GAAGGAATGA TCACGTCCAA 
GGTGGCTGTG CCTGGAGTGG TGCAGAAACC TGCTCAGACT GCCTGCTCAC AGGACCTCAC 
TGCGCCTGGT GCTCCCAGGA GAATTTCACC CACCTGTCCG GAGCTGGCGA AAGGTGCGAC 
ACCCCCGAGA ATCTTTTAGC CAAAGGATGT CAGTTACCCT TCATCGAAAA CCCTGTCTCC 
CAAGTAGAAA TACTTCAAAA TAAGCCTCTC AGCGTAGGTC GACAGAAAAA CAGTTCTGAC 
ATTGTTCAGA TTGCTCCTCA AAGCTTGGTT CTTAAGTTGA GACCAGGGGG TGAGCAGACT 
CTGCAAGTGC AGGTCCGCCA GACGGAAGAT TACCCAGTAG ATCTGTATTA CCTCATGGAC 
CTCTCGGCCT CCATGGATGA TGACCTCAAC ACAATCAAAG AGCTTGGCTC CCGGCTGGCC 
AAAGAGATGT CTAAATTAAC CAGCAACTTT AGACTGGGCT TTGGCTCTTT TGTGGAAAAG 
CCCGTTTCTC CTTTTATGAA AACAACACCA GAGGAAATCA CCAACCCTTG CAGTAGTATC 
CCCTATTTCT GCTTACCTAC ATTTGGATTC AAGCACATTT TGCCATTGAC TGATGATGCT 
GAGAGATTCA ATGAAATTGT GAGGAAACAG AAGATTTCCG CTAATATTGA CACGCCTGAA 
GGCGGATTCG ATGCCATCAT GCAAGCTGCT GTGTGTAAGG AAAAGATTGG CTGGCGCAAC 
GACTCGCTCC ACCTCCTGGT TTTTGTGAGT GATGCTGATT CTCATTTTGG AATGGACAGC 
AAGCTGGCAG GCATTGTGAT TCCCAACGAT GGGCTCTGTC ACTTGGACAA CAGGAATGAA 
TACTCCATGT CAACTGTCTT GGAATATCCA ACGATCGGCC AACTCATTGA TAAACTGGTA 
CAAAACAACG TGCTACTGAT CTTTGCGGTC ACCCAAGAAC AAGTCCATCT CTATGAGAAT 
TATGCGAAAC TCATCCCTGG AGCGACTGTG GGACTGCTTC AGAAGGATTC TGGGAACATT 
CTTCAGCTGA TCATCTCCGC TTACGAAGAA CTGCGGTCTG AGGTGGAACT AGAAGTATTA 
GGAGACACAG AAGGACTCAA CCTGTCTTTC ACAGCTCTCT GTAGCAATGG CATCCTCTTC 
CCACACCAAA AGAAGTGTTC CCACATGAAA GTCGGAGATA CAGCATCCTT CAACGTGTCT 
GTGAGCATAA CAAACTGTGA GAAAAGAAGC AGGAAACTTA TCATCAAGCC TGTGGGACTT 
GGGGACACCC TGGAAATACT CGTCAGCGCA GAATGTGACT GCGACTGCCA GAGAGAAGTA 
GAAGCCAACA GTTCTAAGTG CCACCACGGG AATGGCTCCT TCCAGTGTGG GGTGTGTGCC 
TGCAACCCTG GCCACATGGG TCCTCGCTGC GAGTGCGGCG AGGACATGGT GAGCACGGAT 
TCCTGCAAGG AGTCCCCAGG TCACCCCTCC TGCAGCGGAA GGGGTGACTG CTATTGTGGG 
CAGTGTGTCT GCCACTTGTC TCCCTATGGA AGCATCTATG GACCTTACTG CCAGTGTGAC 
AACTTCTCCT GTCTGAGACA CAAAGGCCTG CTCTGTGGAG ATAATGGTGA CTGTGACTGT 
GGTGAATGCG TGTGCCGGGA TGGCTGGACG GGCGAGTACT GCAACTGTAC AACCAGCAGG 
GATGCGTGTG CATCGGAAGA TGGCGTGCTG TGCAGCGGGC GTGGGGACTG TGTCTGCGGC 
AAGTGTGTCT GCAGAAACCC TGGAGCCTCG GGACCCACCT GTGAACGCTG CCCTACCTGT 
GGAGACCCCT GTAACTCGAG ACGGAGCTGC ATCGAGTGCT ACCTGTCTGC AGATGGCCAG 
GCCCAAGAAG AGTGCGAGGA CAAGTGCAAA GCCACCGGTG CCACCATCAG TGAGGAAGAG 
TTTTCAAAGG ATACTTCTGT CCCCTGCTCG CTACAAGGAG AAAATGAATG TCTTATTACA 
TTCCTAATAA CTGCGGATAA TGAAGGGAAA ACCATCATTC ACAACATCAG TGAAAAAGAC 
TGCCCCAAAC CTCCAAACAT TCCCATGATC ATGTTGGGGG TGTCACTGGC TATCCTGCTC 
ATCGGTGTCG TGCTACTGTG CATTTGGAAG CTGCTGGTAT CCTTTCACGA CCGGAAAGAA 
GTTGCTAAAT TTGAAGCAGA ACGATCAAAG GCCAAGTGGC AAACGGGAAC CAATCCGCTG 
TACCGAGGCT CCACCAGCAC TTTTAAGAAC GTGACCTACA AACACAGGGA GAAGCACAAA 
GTGGGCCTTT CTTCAGATGG GTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Itgb6 ( XM_008761846.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008760068.1 Rattus norvegicus integrin subunit beta 6 (Itgb6), transcript variant X3, mRNA.

Price & Availability↑

CloneID	ORa46938
Clone ID Related Accession (Same CDS sequence)	XM_008761846.2 , XM_008761845.2 , XM_017591686.1
Accession Version	XM_008761846.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2145bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	integrin beta-6 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005102.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008761846.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATCACGT CCAAGGTGGC TGTGCCTGGA GTGGTGCAGA AACCTGCTCA GACTGCCTGC 
TCACAGGACC TCACTGCGCC TGGTGCTCCC AGGAGAATTT CACCCACCTG TCCGGAGCTG 
GCGAAAGGGG GTGAGCAGAC TCTGCAAGTG CAGGTCCGCC AGACGGAAGA TTACCCAGTA 
GATCTGTATT ACCTCATGGA CCTCTCGGCC TCCATGGATG ATGACCTCAA CACAATCAAA 
GAGCTTGGCT CCCGGCTGGC CAAAGAGATG TCTAAATTAA CCAGCAACTT TAGACTGGGC 
TTTGGCTCTT TTGTGGAAAA GCCCGTTTCT CCTTTTATGA AAACAACACC AGAGGAAATC 
ACCAACCCTT GCAGTAGTAT CCCCTATTTC TGCTTACCTA CATTTGGATT CAAGCACATT 
TTGCCATTGA CTGATGATGC TGAGAGATTC AATGAAATTG TGAGGAAACA GAAGATTTCC 
GCTAATATTG ACACGCCTGA AGGCGGATTC GATGCCATCA TGCAAGCTGC TGTGTGTAAG 
GAAAAGATTG GCTGGCGCAA CGACTCGCTC CACCTCCTGG TTTTTGTGAG TGATGCTGAT 
TCTCATTTTG GAATGGACAG CAAGCTGGCA GGCATTGTGA TTCCCAACGA TGGGCTCTGT 
CACTTGGACA ACAGGAATGA ATACTCCATG TCAACTGTCT TGGAATATCC AACGATCGGC 
CAACTCATTG ATAAACTGGT ACAAAACAAC GTGCTACTGA TCTTTGCGGT CACCCAAGAA 
CAAGTCCATC TCTATGAGAA TTATGCGAAA CTCATCCCTG GAGCGACTGT GGGACTGCTT 
CAGAAGGATT CTGGGAACAT TCTTCAGCTG ATCATCTCCG CTTACGAAGA ACTGCGGTCT 
GAGGTGGAAC TAGAAGTATT AGGAGACACA GAAGGACTCA ACCTGTCTTT CACAGCTCTC 
TGTAGCAATG GCATCCTCTT CCCACACCAA AAGAAGTGTT CCCACATGAA AGTCGGAGAT 
ACAGCATCCT TCAACGTGTC TGTGAGCATA ACAAACTGTG AGAAAAGAAG CAGGAAACTT 
ATCATCAAGC CTGTGGGACT TGGGGACACC CTGGAAATAC TCGTCAGCGC AGAATGTGAC 
TGCGACTGCC AGAGAGAAGT AGAAGCCAAC AGTTCTAAGT GCCACCACGG GAATGGCTCC 
TTCCAGTGTG GGGTGTGTGC CTGCAACCCT GGCCACATGG GTCCTCGCTG CGAGTGCGGC 
GAGGACATGG TGAGCACGGA TTCCTGCAAG GAGTCCCCAG GTCACCCCTC CTGCAGCGGA 
AGGGGTGACT GCTATTGTGG GCAGTGTGTC TGCCACTTGT CTCCCTATGG AAGCATCTAT 
GGACCTTACT GCCAGTGTGA CAACTTCTCC TGTCTGAGAC ACAAAGGCCT GCTCTGTGGA 
GATAATGGTG ACTGTGACTG TGGTGAATGC GTGTGCCGGG ATGGCTGGAC GGGCGAGTAC 
TGCAACTGTA CAACCAGCAG GGATGCGTGT GCATCGGAAG ATGGCGTGCT GTGCAGCGGG 
CGTGGGGACT GTGTCTGCGG CAAGTGTGTC TGCAGAAACC CTGGAGCCTC GGGACCCACC 
TGTGAACGCT GCCCTACCTG TGGAGACCCC TGTAACTCGA GACGGAGCTG CATCGAGTGC 
TACCTGTCTG CAGATGGCCA GGCCCAAGAA GAGTGCGAGG ACAAGTGCAA AGCCACCGGT 
GCCACCATCA GTGAGGAAGA GTTTTCAAAG GATACTTCTG TCCCCTGCTC GCTACAAGGA 
GAAAATGAAT GTCTTATTAC ATTCCTAATA ACTGCGGATA ATGAAGGGAA AACCATCATT 
CACAACATCA GTGAAAAAGA CTGCCCCAAA CCTCCAAACA TTCCCATGAT CATGTTGGGG 
GTGTCACTGG CTATCCTGCT CATCGGTGTC GTGCTACTGT GCATTTGGAA GCTGCTGGTA 
TCCTTTCACG ACCGGAAAGA AGTTGCTAAA TTTGAAGCAG AACGATCAAA GGCCAAGTGG 
CAAACGGGAA CCAATCCGCT GTACCGAGGC TCCACCAGCA CTTTTAAGAA CGTGACCTAC 
AAACACAGGG AGAAGCACAA AGTGGGCCTT TCTTCAGATG GGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008760068.1
CDS	431..2575
Translation	MITSKVAVPGVVQKPAQTACSQDLTAPGAPRRISPTCPELAKGGEQTLQVQVRQTEDYPVDLYYLMDLSASMDDDLNTIKELGSRLAKEMSKLTSNFRLGFGSFVEKPVSPFMKTTPEEITNPCSSIPYFCLPTFGFKHILPLTDDAERFNEIVRKQKISANIDTPEGGFDAIMQAAVCKEKIGWRNDSLHLLVFVSDADSHFGMDSKLAGIVIPNDGLCHLDNRNEYSMSTVLEYPTIGQLIDKLVQNNVLLIFAVTQEQVHLYENYAKLIPGATVGLLQKDSGNILQLIISAYEELRSEVELEVLGDTEGLNLSFTALCSNGILFPHQKKCSHMKVGDTASFNVSVSITNCEKRSRKLIIKPVGLGDTLEILVSAECDCDCQREVEANSSKCHHGNGSFQCGVCACNPGHMGPRCECGEDMVSTDSCKESPGHPSCSGRGDCYCGQCVCHLSPYGSIYGPYCQCDNFSCLRHKGLLCGDNGDCDCGECVCRDGWTGEYCNCTTSRDACASEDGVLCSGRGDCVCGKCVCRNPGASGPTCERCPTCGDPCNSRRSCIECYLSADGQAQEECEDKCKATGATISEEEFSKDTSVPCSLQGENECLITFLITADNEGKTIIHNISEKDCPKPPNIPMIMLGVSLAILLIGVVLLCIWKLLVSFHDRKEVAKFEAERSKAKWQTGTNPLYRGSTSTFKNVTYKHREKHKVGLSSDG

Target ORF information:

RefSeq Version	XM_008761846.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus integrin subunit beta 6 (Itgb6), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008761846.2

ORF Insert Sequence:

ATGATCACGT CCAAGGTGGC TGTGCCTGGA GTGGTGCAGA AACCTGCTCA GACTGCCTGC 
TCACAGGACC TCACTGCGCC TGGTGCTCCC AGGAGAATTT CACCCACCTG TCCGGAGCTG 
GCGAAAGGGG GTGAGCAGAC TCTGCAAGTG CAGGTCCGCC AGACGGAAGA TTACCCAGTA 
GATCTGTATT ACCTCATGGA CCTCTCGGCC TCCATGGATG ATGACCTCAA CACAATCAAA 
GAGCTTGGCT CCCGGCTGGC CAAAGAGATG TCTAAATTAA CCAGCAACTT TAGACTGGGC 
TTTGGCTCTT TTGTGGAAAA GCCCGTTTCT CCTTTTATGA AAACAACACC AGAGGAAATC 
ACCAACCCTT GCAGTAGTAT CCCCTATTTC TGCTTACCTA CATTTGGATT CAAGCACATT 
TTGCCATTGA CTGATGATGC TGAGAGATTC AATGAAATTG TGAGGAAACA GAAGATTTCC 
GCTAATATTG ACACGCCTGA AGGCGGATTC GATGCCATCA TGCAAGCTGC TGTGTGTAAG 
GAAAAGATTG GCTGGCGCAA CGACTCGCTC CACCTCCTGG TTTTTGTGAG TGATGCTGAT 
TCTCATTTTG GAATGGACAG CAAGCTGGCA GGCATTGTGA TTCCCAACGA TGGGCTCTGT 
CACTTGGACA ACAGGAATGA ATACTCCATG TCAACTGTCT TGGAATATCC AACGATCGGC 
CAACTCATTG ATAAACTGGT ACAAAACAAC GTGCTACTGA TCTTTGCGGT CACCCAAGAA 
CAAGTCCATC TCTATGAGAA TTATGCGAAA CTCATCCCTG GAGCGACTGT GGGACTGCTT 
CAGAAGGATT CTGGGAACAT TCTTCAGCTG ATCATCTCCG CTTACGAAGA ACTGCGGTCT 
GAGGTGGAAC TAGAAGTATT AGGAGACACA GAAGGACTCA ACCTGTCTTT CACAGCTCTC 
TGTAGCAATG GCATCCTCTT CCCACACCAA AAGAAGTGTT CCCACATGAA AGTCGGAGAT 
ACAGCATCCT TCAACGTGTC TGTGAGCATA ACAAACTGTG AGAAAAGAAG CAGGAAACTT 
ATCATCAAGC CTGTGGGACT TGGGGACACC CTGGAAATAC TCGTCAGCGC AGAATGTGAC 
TGCGACTGCC AGAGAGAAGT AGAAGCCAAC AGTTCTAAGT GCCACCACGG GAATGGCTCC 
TTCCAGTGTG GGGTGTGTGC CTGCAACCCT GGCCACATGG GTCCTCGCTG CGAGTGCGGC 
GAGGACATGG TGAGCACGGA TTCCTGCAAG GAGTCCCCAG GTCACCCCTC CTGCAGCGGA 
AGGGGTGACT GCTATTGTGG GCAGTGTGTC TGCCACTTGT CTCCCTATGG AAGCATCTAT 
GGACCTTACT GCCAGTGTGA CAACTTCTCC TGTCTGAGAC ACAAAGGCCT GCTCTGTGGA 
GATAATGGTG ACTGTGACTG TGGTGAATGC GTGTGCCGGG ATGGCTGGAC GGGCGAGTAC 
TGCAACTGTA CAACCAGCAG GGATGCGTGT GCATCGGAAG ATGGCGTGCT GTGCAGCGGG 
CGTGGGGACT GTGTCTGCGG CAAGTGTGTC TGCAGAAACC CTGGAGCCTC GGGACCCACC 
TGTGAACGCT GCCCTACCTG TGGAGACCCC TGTAACTCGA GACGGAGCTG CATCGAGTGC 
TACCTGTCTG CAGATGGCCA GGCCCAAGAA GAGTGCGAGG ACAAGTGCAA AGCCACCGGT 
GCCACCATCA GTGAGGAAGA GTTTTCAAAG GATACTTCTG TCCCCTGCTC GCTACAAGGA 
GAAAATGAAT GTCTTATTAC ATTCCTAATA ACTGCGGATA ATGAAGGGAA AACCATCATT 
CACAACATCA GTGAAAAAGA CTGCCCCAAA CCTCCAAACA TTCCCATGAT CATGTTGGGG 
GTGTCACTGG CTATCCTGCT CATCGGTGTC GTGCTACTGT GCATTTGGAA GCTGCTGGTA 
TCCTTTCACG ACCGGAAAGA AGTTGCTAAA TTTGAAGCAG AACGATCAAA GGCCAAGTGG 
CAAACGGGAA CCAATCCGCT GTACCGAGGC TCCACCAGCA CTTTTAAGAA CGTGACCTAC 
AAACACAGGG AGAAGCACAA AGTGGGCCTT TCTTCAGATG GGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Itgb6 ( XM_008761845.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008760067.1 Rattus norvegicus integrin subunit beta 6 (Itgb6), transcript variant X4, mRNA.

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CloneID	ORa46938
Clone ID Related Accession (Same CDS sequence)	XM_008761846.2 , XM_008761845.2 , XM_017591686.1
Accession Version	XM_008761845.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2145bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	integrin beta-6 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005102.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008761845.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATCACGT CCAAGGTGGC TGTGCCTGGA GTGGTGCAGA AACCTGCTCA GACTGCCTGC 
TCACAGGACC TCACTGCGCC TGGTGCTCCC AGGAGAATTT CACCCACCTG TCCGGAGCTG 
GCGAAAGGGG GTGAGCAGAC TCTGCAAGTG CAGGTCCGCC AGACGGAAGA TTACCCAGTA 
GATCTGTATT ACCTCATGGA CCTCTCGGCC TCCATGGATG ATGACCTCAA CACAATCAAA 
GAGCTTGGCT CCCGGCTGGC CAAAGAGATG TCTAAATTAA CCAGCAACTT TAGACTGGGC 
TTTGGCTCTT TTGTGGAAAA GCCCGTTTCT CCTTTTATGA AAACAACACC AGAGGAAATC 
ACCAACCCTT GCAGTAGTAT CCCCTATTTC TGCTTACCTA CATTTGGATT CAAGCACATT 
TTGCCATTGA CTGATGATGC TGAGAGATTC AATGAAATTG TGAGGAAACA GAAGATTTCC 
GCTAATATTG ACACGCCTGA AGGCGGATTC GATGCCATCA TGCAAGCTGC TGTGTGTAAG 
GAAAAGATTG GCTGGCGCAA CGACTCGCTC CACCTCCTGG TTTTTGTGAG TGATGCTGAT 
TCTCATTTTG GAATGGACAG CAAGCTGGCA GGCATTGTGA TTCCCAACGA TGGGCTCTGT 
CACTTGGACA ACAGGAATGA ATACTCCATG TCAACTGTCT TGGAATATCC AACGATCGGC 
CAACTCATTG ATAAACTGGT ACAAAACAAC GTGCTACTGA TCTTTGCGGT CACCCAAGAA 
CAAGTCCATC TCTATGAGAA TTATGCGAAA CTCATCCCTG GAGCGACTGT GGGACTGCTT 
CAGAAGGATT CTGGGAACAT TCTTCAGCTG ATCATCTCCG CTTACGAAGA ACTGCGGTCT 
GAGGTGGAAC TAGAAGTATT AGGAGACACA GAAGGACTCA ACCTGTCTTT CACAGCTCTC 
TGTAGCAATG GCATCCTCTT CCCACACCAA AAGAAGTGTT CCCACATGAA AGTCGGAGAT 
ACAGCATCCT TCAACGTGTC TGTGAGCATA ACAAACTGTG AGAAAAGAAG CAGGAAACTT 
ATCATCAAGC CTGTGGGACT TGGGGACACC CTGGAAATAC TCGTCAGCGC AGAATGTGAC 
TGCGACTGCC AGAGAGAAGT AGAAGCCAAC AGTTCTAAGT GCCACCACGG GAATGGCTCC 
TTCCAGTGTG GGGTGTGTGC CTGCAACCCT GGCCACATGG GTCCTCGCTG CGAGTGCGGC 
GAGGACATGG TGAGCACGGA TTCCTGCAAG GAGTCCCCAG GTCACCCCTC CTGCAGCGGA 
AGGGGTGACT GCTATTGTGG GCAGTGTGTC TGCCACTTGT CTCCCTATGG AAGCATCTAT 
GGACCTTACT GCCAGTGTGA CAACTTCTCC TGTCTGAGAC ACAAAGGCCT GCTCTGTGGA 
GATAATGGTG ACTGTGACTG TGGTGAATGC GTGTGCCGGG ATGGCTGGAC GGGCGAGTAC 
TGCAACTGTA CAACCAGCAG GGATGCGTGT GCATCGGAAG ATGGCGTGCT GTGCAGCGGG 
CGTGGGGACT GTGTCTGCGG CAAGTGTGTC TGCAGAAACC CTGGAGCCTC GGGACCCACC 
TGTGAACGCT GCCCTACCTG TGGAGACCCC TGTAACTCGA GACGGAGCTG CATCGAGTGC 
TACCTGTCTG CAGATGGCCA GGCCCAAGAA GAGTGCGAGG ACAAGTGCAA AGCCACCGGT 
GCCACCATCA GTGAGGAAGA GTTTTCAAAG GATACTTCTG TCCCCTGCTC GCTACAAGGA 
GAAAATGAAT GTCTTATTAC ATTCCTAATA ACTGCGGATA ATGAAGGGAA AACCATCATT 
CACAACATCA GTGAAAAAGA CTGCCCCAAA CCTCCAAACA TTCCCATGAT CATGTTGGGG 
GTGTCACTGG CTATCCTGCT CATCGGTGTC GTGCTACTGT GCATTTGGAA GCTGCTGGTA 
TCCTTTCACG ACCGGAAAGA AGTTGCTAAA TTTGAAGCAG AACGATCAAA GGCCAAGTGG 
CAAACGGGAA CCAATCCGCT GTACCGAGGC TCCACCAGCA CTTTTAAGAA CGTGACCTAC 
AAACACAGGG AGAAGCACAA AGTGGGCCTT TCTTCAGATG GGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008760067.1
CDS	455..2599
Translation	MITSKVAVPGVVQKPAQTACSQDLTAPGAPRRISPTCPELAKGGEQTLQVQVRQTEDYPVDLYYLMDLSASMDDDLNTIKELGSRLAKEMSKLTSNFRLGFGSFVEKPVSPFMKTTPEEITNPCSSIPYFCLPTFGFKHILPLTDDAERFNEIVRKQKISANIDTPEGGFDAIMQAAVCKEKIGWRNDSLHLLVFVSDADSHFGMDSKLAGIVIPNDGLCHLDNRNEYSMSTVLEYPTIGQLIDKLVQNNVLLIFAVTQEQVHLYENYAKLIPGATVGLLQKDSGNILQLIISAYEELRSEVELEVLGDTEGLNLSFTALCSNGILFPHQKKCSHMKVGDTASFNVSVSITNCEKRSRKLIIKPVGLGDTLEILVSAECDCDCQREVEANSSKCHHGNGSFQCGVCACNPGHMGPRCECGEDMVSTDSCKESPGHPSCSGRGDCYCGQCVCHLSPYGSIYGPYCQCDNFSCLRHKGLLCGDNGDCDCGECVCRDGWTGEYCNCTTSRDACASEDGVLCSGRGDCVCGKCVCRNPGASGPTCERCPTCGDPCNSRRSCIECYLSADGQAQEECEDKCKATGATISEEEFSKDTSVPCSLQGENECLITFLITADNEGKTIIHNISEKDCPKPPNIPMIMLGVSLAILLIGVVLLCIWKLLVSFHDRKEVAKFEAERSKAKWQTGTNPLYRGSTSTFKNVTYKHREKHKVGLSSDG

Target ORF information:

RefSeq Version	XM_008761845.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus integrin subunit beta 6 (Itgb6), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008761845.2

ORF Insert Sequence:

ATGATCACGT CCAAGGTGGC TGTGCCTGGA GTGGTGCAGA AACCTGCTCA GACTGCCTGC 
TCACAGGACC TCACTGCGCC TGGTGCTCCC AGGAGAATTT CACCCACCTG TCCGGAGCTG 
GCGAAAGGGG GTGAGCAGAC TCTGCAAGTG CAGGTCCGCC AGACGGAAGA TTACCCAGTA 
GATCTGTATT ACCTCATGGA CCTCTCGGCC TCCATGGATG ATGACCTCAA CACAATCAAA 
GAGCTTGGCT CCCGGCTGGC CAAAGAGATG TCTAAATTAA CCAGCAACTT TAGACTGGGC 
TTTGGCTCTT TTGTGGAAAA GCCCGTTTCT CCTTTTATGA AAACAACACC AGAGGAAATC 
ACCAACCCTT GCAGTAGTAT CCCCTATTTC TGCTTACCTA CATTTGGATT CAAGCACATT 
TTGCCATTGA CTGATGATGC TGAGAGATTC AATGAAATTG TGAGGAAACA GAAGATTTCC 
GCTAATATTG ACACGCCTGA AGGCGGATTC GATGCCATCA TGCAAGCTGC TGTGTGTAAG 
GAAAAGATTG GCTGGCGCAA CGACTCGCTC CACCTCCTGG TTTTTGTGAG TGATGCTGAT 
TCTCATTTTG GAATGGACAG CAAGCTGGCA GGCATTGTGA TTCCCAACGA TGGGCTCTGT 
CACTTGGACA ACAGGAATGA ATACTCCATG TCAACTGTCT TGGAATATCC AACGATCGGC 
CAACTCATTG ATAAACTGGT ACAAAACAAC GTGCTACTGA TCTTTGCGGT CACCCAAGAA 
CAAGTCCATC TCTATGAGAA TTATGCGAAA CTCATCCCTG GAGCGACTGT GGGACTGCTT 
CAGAAGGATT CTGGGAACAT TCTTCAGCTG ATCATCTCCG CTTACGAAGA ACTGCGGTCT 
GAGGTGGAAC TAGAAGTATT AGGAGACACA GAAGGACTCA ACCTGTCTTT CACAGCTCTC 
TGTAGCAATG GCATCCTCTT CCCACACCAA AAGAAGTGTT CCCACATGAA AGTCGGAGAT 
ACAGCATCCT TCAACGTGTC TGTGAGCATA ACAAACTGTG AGAAAAGAAG CAGGAAACTT 
ATCATCAAGC CTGTGGGACT TGGGGACACC CTGGAAATAC TCGTCAGCGC AGAATGTGAC 
TGCGACTGCC AGAGAGAAGT AGAAGCCAAC AGTTCTAAGT GCCACCACGG GAATGGCTCC 
TTCCAGTGTG GGGTGTGTGC CTGCAACCCT GGCCACATGG GTCCTCGCTG CGAGTGCGGC 
GAGGACATGG TGAGCACGGA TTCCTGCAAG GAGTCCCCAG GTCACCCCTC CTGCAGCGGA 
AGGGGTGACT GCTATTGTGG GCAGTGTGTC TGCCACTTGT CTCCCTATGG AAGCATCTAT 
GGACCTTACT GCCAGTGTGA CAACTTCTCC TGTCTGAGAC ACAAAGGCCT GCTCTGTGGA 
GATAATGGTG ACTGTGACTG TGGTGAATGC GTGTGCCGGG ATGGCTGGAC GGGCGAGTAC 
TGCAACTGTA CAACCAGCAG GGATGCGTGT GCATCGGAAG ATGGCGTGCT GTGCAGCGGG 
CGTGGGGACT GTGTCTGCGG CAAGTGTGTC TGCAGAAACC CTGGAGCCTC GGGACCCACC 
TGTGAACGCT GCCCTACCTG TGGAGACCCC TGTAACTCGA GACGGAGCTG CATCGAGTGC 
TACCTGTCTG CAGATGGCCA GGCCCAAGAA GAGTGCGAGG ACAAGTGCAA AGCCACCGGT 
GCCACCATCA GTGAGGAAGA GTTTTCAAAG GATACTTCTG TCCCCTGCTC GCTACAAGGA 
GAAAATGAAT GTCTTATTAC ATTCCTAATA ACTGCGGATA ATGAAGGGAA AACCATCATT 
CACAACATCA GTGAAAAAGA CTGCCCCAAA CCTCCAAACA TTCCCATGAT CATGTTGGGG 
GTGTCACTGG CTATCCTGCT CATCGGTGTC GTGCTACTGT GCATTTGGAA GCTGCTGGTA 
TCCTTTCACG ACCGGAAAGA AGTTGCTAAA TTTGAAGCAG AACGATCAAA GGCCAAGTGG 
CAAACGGGAA CCAATCCGCT GTACCGAGGC TCCACCAGCA CTTTTAAGAA CGTGACCTAC 
AAACACAGGG AGAAGCACAA AGTGGGCCTT TCTTCAGATG GGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Itgb6 ( XM_017591686.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017447175.1 Rattus norvegicus integrin subunit beta 6 (Itgb6), transcript variant X5, mRNA.

Price & Availability↑

CloneID	ORa46938
Clone ID Related Accession (Same CDS sequence)	XM_008761846.2 , XM_008761845.2 , XM_017591686.1
Accession Version	XM_017591686.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2145bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	integrin beta-6 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005102.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATCACGT CCAAGGTGGC TGTGCCTGGA GTGGTGCAGA AACCTGCTCA GACTGCCTGC 
TCACAGGACC TCACTGCGCC TGGTGCTCCC AGGAGAATTT CACCCACCTG TCCGGAGCTG 
GCGAAAGGGG GTGAGCAGAC TCTGCAAGTG CAGGTCCGCC AGACGGAAGA TTACCCAGTA 
GATCTGTATT ACCTCATGGA CCTCTCGGCC TCCATGGATG ATGACCTCAA CACAATCAAA 
GAGCTTGGCT CCCGGCTGGC CAAAGAGATG TCTAAATTAA CCAGCAACTT TAGACTGGGC 
TTTGGCTCTT TTGTGGAAAA GCCCGTTTCT CCTTTTATGA AAACAACACC AGAGGAAATC 
ACCAACCCTT GCAGTAGTAT CCCCTATTTC TGCTTACCTA CATTTGGATT CAAGCACATT 
TTGCCATTGA CTGATGATGC TGAGAGATTC AATGAAATTG TGAGGAAACA GAAGATTTCC 
GCTAATATTG ACACGCCTGA AGGCGGATTC GATGCCATCA TGCAAGCTGC TGTGTGTAAG 
GAAAAGATTG GCTGGCGCAA CGACTCGCTC CACCTCCTGG TTTTTGTGAG TGATGCTGAT 
TCTCATTTTG GAATGGACAG CAAGCTGGCA GGCATTGTGA TTCCCAACGA TGGGCTCTGT 
CACTTGGACA ACAGGAATGA ATACTCCATG TCAACTGTCT TGGAATATCC AACGATCGGC 
CAACTCATTG ATAAACTGGT ACAAAACAAC GTGCTACTGA TCTTTGCGGT CACCCAAGAA 
CAAGTCCATC TCTATGAGAA TTATGCGAAA CTCATCCCTG GAGCGACTGT GGGACTGCTT 
CAGAAGGATT CTGGGAACAT TCTTCAGCTG ATCATCTCCG CTTACGAAGA ACTGCGGTCT 
GAGGTGGAAC TAGAAGTATT AGGAGACACA GAAGGACTCA ACCTGTCTTT CACAGCTCTC 
TGTAGCAATG GCATCCTCTT CCCACACCAA AAGAAGTGTT CCCACATGAA AGTCGGAGAT 
ACAGCATCCT TCAACGTGTC TGTGAGCATA ACAAACTGTG AGAAAAGAAG CAGGAAACTT 
ATCATCAAGC CTGTGGGACT TGGGGACACC CTGGAAATAC TCGTCAGCGC AGAATGTGAC 
TGCGACTGCC AGAGAGAAGT AGAAGCCAAC AGTTCTAAGT GCCACCACGG GAATGGCTCC 
TTCCAGTGTG GGGTGTGTGC CTGCAACCCT GGCCACATGG GTCCTCGCTG CGAGTGCGGC 
GAGGACATGG TGAGCACGGA TTCCTGCAAG GAGTCCCCAG GTCACCCCTC CTGCAGCGGA 
AGGGGTGACT GCTATTGTGG GCAGTGTGTC TGCCACTTGT CTCCCTATGG AAGCATCTAT 
GGACCTTACT GCCAGTGTGA CAACTTCTCC TGTCTGAGAC ACAAAGGCCT GCTCTGTGGA 
GATAATGGTG ACTGTGACTG TGGTGAATGC GTGTGCCGGG ATGGCTGGAC GGGCGAGTAC 
TGCAACTGTA CAACCAGCAG GGATGCGTGT GCATCGGAAG ATGGCGTGCT GTGCAGCGGG 
CGTGGGGACT GTGTCTGCGG CAAGTGTGTC TGCAGAAACC CTGGAGCCTC GGGACCCACC 
TGTGAACGCT GCCCTACCTG TGGAGACCCC TGTAACTCGA GACGGAGCTG CATCGAGTGC 
TACCTGTCTG CAGATGGCCA GGCCCAAGAA GAGTGCGAGG ACAAGTGCAA AGCCACCGGT 
GCCACCATCA GTGAGGAAGA GTTTTCAAAG GATACTTCTG TCCCCTGCTC GCTACAAGGA 
GAAAATGAAT GTCTTATTAC ATTCCTAATA ACTGCGGATA ATGAAGGGAA AACCATCATT 
CACAACATCA GTGAAAAAGA CTGCCCCAAA CCTCCAAACA TTCCCATGAT CATGTTGGGG 
GTGTCACTGG CTATCCTGCT CATCGGTGTC GTGCTACTGT GCATTTGGAA GCTGCTGGTA 
TCCTTTCACG ACCGGAAAGA AGTTGCTAAA TTTGAAGCAG AACGATCAAA GGCCAAGTGG 
CAAACGGGAA CCAATCCGCT GTACCGAGGC TCCACCAGCA CTTTTAAGAA CGTGACCTAC 
AAACACAGGG AGAAGCACAA AGTGGGCCTT TCTTCAGATG GGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017447175.1
CDS	163..2307
Translation	MITSKVAVPGVVQKPAQTACSQDLTAPGAPRRISPTCPELAKGGEQTLQVQVRQTEDYPVDLYYLMDLSASMDDDLNTIKELGSRLAKEMSKLTSNFRLGFGSFVEKPVSPFMKTTPEEITNPCSSIPYFCLPTFGFKHILPLTDDAERFNEIVRKQKISANIDTPEGGFDAIMQAAVCKEKIGWRNDSLHLLVFVSDADSHFGMDSKLAGIVIPNDGLCHLDNRNEYSMSTVLEYPTIGQLIDKLVQNNVLLIFAVTQEQVHLYENYAKLIPGATVGLLQKDSGNILQLIISAYEELRSEVELEVLGDTEGLNLSFTALCSNGILFPHQKKCSHMKVGDTASFNVSVSITNCEKRSRKLIIKPVGLGDTLEILVSAECDCDCQREVEANSSKCHHGNGSFQCGVCACNPGHMGPRCECGEDMVSTDSCKESPGHPSCSGRGDCYCGQCVCHLSPYGSIYGPYCQCDNFSCLRHKGLLCGDNGDCDCGECVCRDGWTGEYCNCTTSRDACASEDGVLCSGRGDCVCGKCVCRNPGASGPTCERCPTCGDPCNSRRSCIECYLSADGQAQEECEDKCKATGATISEEEFSKDTSVPCSLQGENECLITFLITADNEGKTIIHNISEKDCPKPPNIPMIMLGVSLAILLIGVVLLCIWKLLVSFHDRKEVAKFEAERSKAKWQTGTNPLYRGSTSTFKNVTYKHREKHKVGLSSDG

Target ORF information:

RefSeq Version	XM_017591686.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus integrin subunit beta 6 (Itgb6), transcript variant X5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017591686.1

ORF Insert Sequence:

ATGATCACGT CCAAGGTGGC TGTGCCTGGA GTGGTGCAGA AACCTGCTCA GACTGCCTGC 
TCACAGGACC TCACTGCGCC TGGTGCTCCC AGGAGAATTT CACCCACCTG TCCGGAGCTG 
GCGAAAGGGG GTGAGCAGAC TCTGCAAGTG CAGGTCCGCC AGACGGAAGA TTACCCAGTA 
GATCTGTATT ACCTCATGGA CCTCTCGGCC TCCATGGATG ATGACCTCAA CACAATCAAA 
GAGCTTGGCT CCCGGCTGGC CAAAGAGATG TCTAAATTAA CCAGCAACTT TAGACTGGGC 
TTTGGCTCTT TTGTGGAAAA GCCCGTTTCT CCTTTTATGA AAACAACACC AGAGGAAATC 
ACCAACCCTT GCAGTAGTAT CCCCTATTTC TGCTTACCTA CATTTGGATT CAAGCACATT 
TTGCCATTGA CTGATGATGC TGAGAGATTC AATGAAATTG TGAGGAAACA GAAGATTTCC 
GCTAATATTG ACACGCCTGA AGGCGGATTC GATGCCATCA TGCAAGCTGC TGTGTGTAAG 
GAAAAGATTG GCTGGCGCAA CGACTCGCTC CACCTCCTGG TTTTTGTGAG TGATGCTGAT 
TCTCATTTTG GAATGGACAG CAAGCTGGCA GGCATTGTGA TTCCCAACGA TGGGCTCTGT 
CACTTGGACA ACAGGAATGA ATACTCCATG TCAACTGTCT TGGAATATCC AACGATCGGC 
CAACTCATTG ATAAACTGGT ACAAAACAAC GTGCTACTGA TCTTTGCGGT CACCCAAGAA 
CAAGTCCATC TCTATGAGAA TTATGCGAAA CTCATCCCTG GAGCGACTGT GGGACTGCTT 
CAGAAGGATT CTGGGAACAT TCTTCAGCTG ATCATCTCCG CTTACGAAGA ACTGCGGTCT 
GAGGTGGAAC TAGAAGTATT AGGAGACACA GAAGGACTCA ACCTGTCTTT CACAGCTCTC 
TGTAGCAATG GCATCCTCTT CCCACACCAA AAGAAGTGTT CCCACATGAA AGTCGGAGAT 
ACAGCATCCT TCAACGTGTC TGTGAGCATA ACAAACTGTG AGAAAAGAAG CAGGAAACTT 
ATCATCAAGC CTGTGGGACT TGGGGACACC CTGGAAATAC TCGTCAGCGC AGAATGTGAC 
TGCGACTGCC AGAGAGAAGT AGAAGCCAAC AGTTCTAAGT GCCACCACGG GAATGGCTCC 
TTCCAGTGTG GGGTGTGTGC CTGCAACCCT GGCCACATGG GTCCTCGCTG CGAGTGCGGC 
GAGGACATGG TGAGCACGGA TTCCTGCAAG GAGTCCCCAG GTCACCCCTC CTGCAGCGGA 
AGGGGTGACT GCTATTGTGG GCAGTGTGTC TGCCACTTGT CTCCCTATGG AAGCATCTAT 
GGACCTTACT GCCAGTGTGA CAACTTCTCC TGTCTGAGAC ACAAAGGCCT GCTCTGTGGA 
GATAATGGTG ACTGTGACTG TGGTGAATGC GTGTGCCGGG ATGGCTGGAC GGGCGAGTAC 
TGCAACTGTA CAACCAGCAG GGATGCGTGT GCATCGGAAG ATGGCGTGCT GTGCAGCGGG 
CGTGGGGACT GTGTCTGCGG CAAGTGTGTC TGCAGAAACC CTGGAGCCTC GGGACCCACC 
TGTGAACGCT GCCCTACCTG TGGAGACCCC TGTAACTCGA GACGGAGCTG CATCGAGTGC 
TACCTGTCTG CAGATGGCCA GGCCCAAGAA GAGTGCGAGG ACAAGTGCAA AGCCACCGGT 
GCCACCATCA GTGAGGAAGA GTTTTCAAAG GATACTTCTG TCCCCTGCTC GCTACAAGGA 
GAAAATGAAT GTCTTATTAC ATTCCTAATA ACTGCGGATA ATGAAGGGAA AACCATCATT 
CACAACATCA GTGAAAAAGA CTGCCCCAAA CCTCCAAACA TTCCCATGAT CATGTTGGGG 
GTGTCACTGG CTATCCTGCT CATCGGTGTC GTGCTACTGT GCATTTGGAA GCTGCTGGTA 
TCCTTTCACG ACCGGAAAGA AGTTGCTAAA TTTGAAGCAG AACGATCAAA GGCCAAGTGG 
CAAACGGGAA CCAATCCGCT GTACCGAGGC TCCACCAGCA CTTTTAAGAA CGTGACCTAC 
AAACACAGGG AGAAGCACAA AGTGGGCCTT TCTTCAGATG GGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Interleukin-1? Promotes Epithelial-Derived Alveolar Elastogenesis via ?v?6 Integrin-Dependent TGF-? Activation.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology36(6)2198-216(2015)
Wang J,Bao L,Yu B,Liu Z,Han W,Deng C,Guo C

Kindlin-1 controls Wnt and TGF-? availability to regulate cutaneous stem cell proliferation.
Nature medicine20(4)350-9(2014 Apr)
Rognoni E,Widmaier M,Jakobson M,Ruppert R,Ussar S,Katsougkri D,B?ttcher RT,Lai-Cheong JE,Rifkin DB,McGrath JA,F?ssler R

Role of integrin ?v?6 in the pathogenesis of ischemia-related biliary fibrosis after liver transplantation.
Transplantation95(9)1092-9(2013 May)
Chen G,Zhang L,Chen L,Wang H,Zhang Y,Bie P

Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.
Proceedings of the National Academy of Sciences of the United States of America110(8)E643-52(2013 Feb)
Ghai R,Bugarcic A,Liu H,Norwood SJ,Skeldal S,Coulson EJ,Li SS,Teasdale RD,Collins BM

Lysophosphatidic acid increases proximal tubule cell secretion of profibrotic cytokines PDGF-B and CTGF through LPA2- and G?q-mediated Rho and ?v?6 integrin-dependent activation of TGF-?.
The American journal of pathology181(4)1236-49(2012 Oct)
Geng H,Lan R,Singha PK,Gilchrist A,Weinreb PH,Violette SM,Weinberg JM,Saikumar P,Venkatachalam MA

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Itgb6 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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