Kdm8 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Kdm8
Entrez Gene ID	308976
Full Name	lysine demethylase 8
Synonyms	Jmjd5,RGD1304823
General protein information	Preferred Names lysine demethylase 8 Names jmjC domain-containing protein 5 lysine-specific demethylase 8 jumonji domain containing 5 jumonji domain-containing protein 5 lysine (K)-specific demethylase 8
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 1 Map Location: 1q36

mRNA and Protein(s)

mRNA	Protein	Name
XM_006230258.3	XP_006230320.1	lysine-specific demethylase 8 isoform X1
NM_001037196.1	NP_001032273.1	bifunctional peptidase and arginyl-hydroxylase JMJD5
XM_006230259.3	XP_006230321.1	lysine-specific demethylase 8 isoform X2

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	JMJD5	XP_003315073.1
Danio rerio (zebrafish)	kdm8	NP_001103339.2
Drosophila melanogaster (fruit fly)	CG13902	NP_612063.2
	JMJD5	XP_001100489.1
Xenopus tropicalis (tropical clawed frog)	kdm8	NP_001121525.1
Homo sapiens (human)	KDM8	NP_001138820.1
Canis lupus familiaris (dog)	KDM8	XP_850038.1
Rattus norvegicus (Norway rat)	Kdm8	NP_001032273.1
Arabidopsis thaliana (thale cress)	AT3G20810	NP_850617.1
Oryza sativa (rice)	Os09g0489200	NP_001063533.2
Mus musculus (house mouse)	Kdm8	NP_084118.1
Oryza sativa (rice)	Os08g0508500	NP_001175654.1
Bos taurus (cattle)	KDM8	NP_001068807.1
Gallus gallus (chicken)	KDM8	XP_414883.3
Caenorhabditis elegans (roundworm)	jmjd-5	NP_505831.1

Gene Ontology
Bibliography

Related articles in PubMed

Clipping of arginine-methylated histone tails by JMJD5 and JMJD7.
Liu H, Wang C, Lee S, Deng Y, Wither M, Oh S, Ning F, Dege C, Zhang Q, Liu X, Johnson AM, Zang J, Chen Z, Janknecht R, Hansen K, Marrack P, Li CY, Kappler JW, Hagman J, Zhang G
Proceedings of the National Academy of Sciences of the United States of America114(37)E7717-E7726(2017 Sep)

Histone lysine methylation dynamics: establishment, regulation, and biological impact.
Black JC, Van Rechem C, Whetstine JR
Molecular cell48(4)491-507(2012 Nov)

Differential proteome profiling of pleural effusions from lung cancer and benign inflammatory disease patients.
Wang Z, Wang C, Huang X, Shen Y, Shen J, Ying K
Biochimica et biophysica acta1824(4)692-700(2012 Apr)

KDM8, a H3K36me2 histone demethylase that acts in the cyclin A1 coding region to regulate cancer cell proliferation.
Hsia DA, Tepper CG, Pochampalli MR, Hsia EY, Izumiya C, Huerta SB, Wright ME, Chen HW, Kung HJ, Izumiya Y
Proceedings of the National Academy of Sciences of the United States of America107(21)9671-6(2010 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Kdm8 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Kdm8 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa09036	NM_001037196.1 Latest version!	Rattus norvegicus lysine demethylase 8 (Kdm8), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00
ORa23430	XM_006230258.3 Latest version!	Rattus norvegicus lysine demethylase 8 (Kdm8), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
ORa23431	XM_006230259.3 Latest version!	Rattus norvegicus lysine demethylase 8 (Kdm8), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Kdm8 ( NM_001037196.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001032273.1 Rattus norvegicus lysine demethylase 8 (Kdm8), mRNA.

Price & Availability↑

CloneID	ORa09036
Clone ID Related Accession (Same CDS sequence)	NM_001037196.1
Accession Version	NM_001037196.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1245bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-09
Organism	Rattus norvegicus(Norway rat)
Product	bifunctional peptidase and arginyl-hydroxylase JMJD5
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC100627.1. On Nov 18, 2005 this sequence version replaced XM_219312.3. ##Evidence-Data-START## Transcript exon combination :: BC100627.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGTCAGAGG ACACTACAGA GCCCCTAGTG GGGCCCAGCA CCCTCTGGAA GGACCTCAGG 
GCGCTCCTGC CAGACACAGA GGAGGAGCTG AAGCTGGATC TCAGTGAGAA GGTGGACAGG 
AGCATGGCTA CGCTGCTACG GCAGGCTTTG GGTCTGTTCT ATGAAGGCCG TTGGCAGAAG 
TGCCTGCAGG CCAGTGAGGC TGTCCTGGAC TACTCCTGGG AAAAGCTCAA CACTGGTCCC 
TGGCGAGATG TAGACAAGGA ATGGCGCCGG GTATATTCCT TCGGCTGCCT CCTGAAGACC 
CTGTGCCTGT GCCAGGCACC ACAGAAGGCC ACTGCTGTGG CTGAAGCACT GCGGGTGTGT 
GACATGGGCC TGTTGATGGG GGCAGCCATC CTTGGGGACA TTCTTCTCAA AGTTGCTACA 
GTCCTCCAGA CACATCTGCT CCCTAGAAAG CAGCCTGCCT GTGGCCCTCA CCAGGATCAG 
CCTGCTACCA AGAAGGCAAA GCATGATGCC AGCTCAACTC CTGATGTGGT ATTAGATCGG 
GAAGTGCCCA GGCTTCGCTG CCCACCTCTG CAGCACTTCA AGAAGCATTT TCTAGTTCCT 
GGGAGACCTG TGATCTTGGA AGGTGTGGCT GACCACTGGC CGTGCATGAA GAAGTGGAGT 
CTACAGTACA TCCAGGAGAT TGCTGGCTGC CGCACTGTCC CCGTGGAAGT GGGTTCAAGA 
TACACAGATG AAGACTGGTC CCAGACTCTC ATGACAGTCA ATGAGTTCAT CCACAAATAC 
ATTCTGAGCG AGGCAAAGGA TGTCGGGTAC CTTGCTCAAC ACCAGCTGTT CGACCAGATC 
CCAGAGTTGA AGCAGGACAT CAGCATCCCC GATTACTGTT GCCTGGGCAA TGGAGAAGAG 
GAAGAGATCA CTATCAATGC CTGGTTTGGT CCTCAAGGAA CCATCTCCCC ATTGCATCAG 
GACCCCCAGC AGAACTTCCT GGTCCAGGTG TTAGGAAGGA AGTACATCCG GCTGTATTCT 
CCGCAAGAGT CTGAGGCAGT GTACCCTCAT GAGACACACA TTCTTCATAA CACCAGCCAG 
GTTGATGTGG AAAACCCCGA CCTAGAGAAG TTCCCCAAGT TCACCGAGGC CCCGTTTCTG 
TCCTGCATTC TGTCCCCAGG AGACACCCTC TTTATACCTG CTAAGTACTG GCATTACGTG 
CGCTCCCTGG ACCTGAGCTT CTCTGTCAGC TTCTGGTGGT CATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001032273.1
CDS	274..1518
Translation	MSEDTTEPLVGPSTLWKDLRALLPDTEEELKLDLSEKVDRSMATLLRQALGLFYEGRWQKCLQASEAVLDYSWEKLNTGPWRDVDKEWRRVYSFGCLLKTLCLCQAPQKATAVAEALRVCDMGLLMGAAILGDILLKVATVLQTHLLPRKQPACGPHQDQPATKKAKHDASSTPDVVLDREVPRLRCPPLQHFKKHFLVPGRPVILEGVADHWPCMKKWSLQYIQEIAGCRTVPVEVGSRYTDEDWSQTLMTVNEFIHKYILSEAKDVGYLAQHQLFDQIPELKQDISIPDYCCLGNGEEEEITINAWFGPQGTISPLHQDPQQNFLVQVLGRKYIRLYSPQESEAVYPHETHILHNTSQVDVENPDLEKFPKFTEAPFLSCILSPGDTLFIPAKYWHYVRSLDLSFSVSFWWS

Target ORF information:

RefSeq Version	NM_001037196.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus lysine demethylase 8 (Kdm8), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001037196.1

ORF Insert Sequence:

ATGTCAGAGG ACACTACAGA GCCCCTAGTG GGGCCCAGCA CCCTCTGGAA GGACCTCAGG 
GCGCTCCTGC CAGACACAGA GGAGGAGCTG AAGCTGGATC TCAGTGAGAA GGTGGACAGG 
AGCATGGCTA CGCTGCTACG GCAGGCTTTG GGTCTGTTCT ATGAAGGCCG TTGGCAGAAG 
TGCCTGCAGG CCAGTGAGGC TGTCCTGGAC TACTCCTGGG AAAAGCTCAA CACTGGTCCC 
TGGCGAGATG TAGACAAGGA ATGGCGCCGG GTATATTCCT TCGGCTGCCT CCTGAAGACC 
CTGTGCCTGT GCCAGGCACC ACAGAAGGCC ACTGCTGTGG CTGAAGCACT GCGGGTGTGT 
GACATGGGCC TGTTGATGGG GGCAGCCATC CTTGGGGACA TTCTTCTCAA AGTTGCTACA 
GTCCTCCAGA CACATCTGCT CCCTAGAAAG CAGCCTGCCT GTGGCCCTCA CCAGGATCAG 
CCTGCTACCA AGAAGGCAAA GCATGATGCC AGCTCAACTC CTGATGTGGT ATTAGATCGG 
GAAGTGCCCA GGCTTCGCTG CCCACCTCTG CAGCACTTCA AGAAGCATTT TCTAGTTCCT 
GGGAGACCTG TGATCTTGGA AGGTGTGGCT GACCACTGGC CGTGCATGAA GAAGTGGAGT 
CTACAGTACA TCCAGGAGAT TGCTGGCTGC CGCACTGTCC CCGTGGAAGT GGGTTCAAGA 
TACACAGATG AAGACTGGTC CCAGACTCTC ATGACAGTCA ATGAGTTCAT CCACAAATAC 
ATTCTGAGCG AGGCAAAGGA TGTCGGGTAC CTTGCTCAAC ACCAGCTGTT CGACCAGATC 
CCAGAGTTGA AGCAGGACAT CAGCATCCCC GATTACTGTT GCCTGGGCAA TGGAGAAGAG 
GAAGAGATCA CTATCAATGC CTGGTTTGGT CCTCAAGGAA CCATCTCCCC ATTGCATCAG 
GACCCCCAGC AGAACTTCCT GGTCCAGGTG TTAGGAAGGA AGTACATCCG GCTGTATTCT 
CCGCAAGAGT CTGAGGCAGT GTACCCTCAT GAGACACACA TTCTTCATAA CACCAGCCAG 
GTTGATGTGG AAAACCCCGA CCTAGAGAAG TTCCCCAAGT TCACCGAGGC CCCGTTTCTG 
TCCTGCATTC TGTCCCCAGG AGACACCCTC TTTATACCTG CTAAGTACTG GCATTACGTG 
CGCTCCCTGG ACCTGAGCTT CTCTGTCAGC TTCTGGTGGT CATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Kdm8 ( XM_006230258.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006230320.1 Rattus norvegicus lysine demethylase 8 (Kdm8), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa23430
Clone ID Related Accession (Same CDS sequence)	XM_006230258.3
Accession Version	XM_006230258.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1245bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	lysine-specific demethylase 8 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006230258.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCAGAGG ACACTACAGA GCCCCTAGTG GGGCCCAGCA TCCTCTGGAA GGACCTCAGG 
GTGCTCCTGC CAGACACAGA GGAGGAGCTG AAGCTGGATC TCAGTGAGAA GGTGGACAGG 
AGCGTGGCTA CGCTGCTACG GCAGGCTTTG GGTCTGTTCT ATGAAGGCCG TTGGCAGAAG 
TGCCTGCAGG CCAGTGAGGC TGTCCTGGAC TACTCCTGGG AAAAGCTCAA CACTGGTCCC 
TGGCGAGATG TAGACAAGGA ATGGCGCCGG GTATATTCCT TCGGCTGCCT CCTGAAGACC 
CTGTGCCTGT GCCAGGCACC ACAGAAGGCC ACTGCTGTGG CTGAAGCACT GCGGGTGTGT 
GACATGGGCC TGTTGATGGG GGCAGCCATC CTTGGGGACA TTCTTCTCAA AGTTGCTACA 
GTCCTCCAGA CACATCTGCT CCCTAGAAAG CAGCCTGCCT GTGGCCCTCA CCAGGATCAG 
CCTGCTACCA AGAAGGCAAA GCATGATGCC AGCTCAACTC CTGATGTGGT ATTAGATCGG 
GAAGTGCCCA GGCTTCGCTG CCCACCTCTG CAGCACTTCA AGAAGCATTT TCTAGTTCCT 
GGGAGACCTG TGATCTTGGA AGGTGTGGCT GACCACTGGC CGTGCATGAA GAAGTGGAGT 
CTACAGTACA TCCAGGAGAT TGCTGGCTGC CGCACTGTCC CCGTGGAAGT GGGTTCAAGA 
TACACAGATG AAGACTGGTC CCAGACTCTC ATGACAGTCA ATGAGTTCAT CCACAAATAC 
ATTCTGAGCG AGGCAAAGGA TGTCGGGTAC CTTGCTCAAC ACCAGCTGTT CGACCAGATC 
CCAGAGTTGA AGCAGGACAT CAGCATCCCC GATTACTGTT GCCTGGGCAA TGGAGAAGAG 
GAAGAGATCA CTATCAATGC CTGGTTTGGT CCTCAAGGAA CCATCTCCCC ATTGCATCAG 
GACCCCCAGC AGAACTTCCT GGTCCAGGTG TTAGGAAGGA AGTACATCCG GCTGTATTCT 
CCGCAAGAGT CTGAGGCAGT GTACCCTCAT GAGACACACA TTCTTCATAA CACCAGCCAG 
GTTGATGTGG AAAACCCCGA CCTAGAGAAG TTCCCCAAGT TCACCGAGGC CCCGTTTCTG 
TCCTGCATTC TGTCCCCAGG AGACACCCTC TTTATACCTG CTAAGTACTG GCATTACGTG 
CGCTCCCTGG ACCTGAGCTT CTCTGTCAGC TTCTGGTGGT CATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006230320.1
CDS	957..2201
Translation	MSEDTTEPLVGPSILWKDLRVLLPDTEEELKLDLSEKVDRSVATLLRQALGLFYEGRWQKCLQASEAVLDYSWEKLNTGPWRDVDKEWRRVYSFGCLLKTLCLCQAPQKATAVAEALRVCDMGLLMGAAILGDILLKVATVLQTHLLPRKQPACGPHQDQPATKKAKHDASSTPDVVLDREVPRLRCPPLQHFKKHFLVPGRPVILEGVADHWPCMKKWSLQYIQEIAGCRTVPVEVGSRYTDEDWSQTLMTVNEFIHKYILSEAKDVGYLAQHQLFDQIPELKQDISIPDYCCLGNGEEEEITINAWFGPQGTISPLHQDPQQNFLVQVLGRKYIRLYSPQESEAVYPHETHILHNTSQVDVENPDLEKFPKFTEAPFLSCILSPGDTLFIPAKYWHYVRSLDLSFSVSFWWS

Target ORF information:

RefSeq Version	XM_006230258.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus lysine demethylase 8 (Kdm8), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006230258.3

ORF Insert Sequence:

ATGTCAGAGG ACACTACAGA GCCCCTAGTG GGGCCCAGCA TCCTCTGGAA GGACCTCAGG 
GTGCTCCTGC CAGACACAGA GGAGGAGCTG AAGCTGGATC TCAGTGAGAA GGTGGACAGG 
AGCGTGGCTA CGCTGCTACG GCAGGCTTTG GGTCTGTTCT ATGAAGGCCG TTGGCAGAAG 
TGCCTGCAGG CCAGTGAGGC TGTCCTGGAC TACTCCTGGG AAAAGCTCAA CACTGGTCCC 
TGGCGAGATG TAGACAAGGA ATGGCGCCGG GTATATTCCT TCGGCTGCCT CCTGAAGACC 
CTGTGCCTGT GCCAGGCACC ACAGAAGGCC ACTGCTGTGG CTGAAGCACT GCGGGTGTGT 
GACATGGGCC TGTTGATGGG GGCAGCCATC CTTGGGGACA TTCTTCTCAA AGTTGCTACA 
GTCCTCCAGA CACATCTGCT CCCTAGAAAG CAGCCTGCCT GTGGCCCTCA CCAGGATCAG 
CCTGCTACCA AGAAGGCAAA GCATGATGCC AGCTCAACTC CTGATGTGGT ATTAGATCGG 
GAAGTGCCCA GGCTTCGCTG CCCACCTCTG CAGCACTTCA AGAAGCATTT TCTAGTTCCT 
GGGAGACCTG TGATCTTGGA AGGTGTGGCT GACCACTGGC CGTGCATGAA GAAGTGGAGT 
CTACAGTACA TCCAGGAGAT TGCTGGCTGC CGCACTGTCC CCGTGGAAGT GGGTTCAAGA 
TACACAGATG AAGACTGGTC CCAGACTCTC ATGACAGTCA ATGAGTTCAT CCACAAATAC 
ATTCTGAGCG AGGCAAAGGA TGTCGGGTAC CTTGCTCAAC ACCAGCTGTT CGACCAGATC 
CCAGAGTTGA AGCAGGACAT CAGCATCCCC GATTACTGTT GCCTGGGCAA TGGAGAAGAG 
GAAGAGATCA CTATCAATGC CTGGTTTGGT CCTCAAGGAA CCATCTCCCC ATTGCATCAG 
GACCCCCAGC AGAACTTCCT GGTCCAGGTG TTAGGAAGGA AGTACATCCG GCTGTATTCT 
CCGCAAGAGT CTGAGGCAGT GTACCCTCAT GAGACACACA TTCTTCATAA CACCAGCCAG 
GTTGATGTGG AAAACCCCGA CCTAGAGAAG TTCCCCAAGT TCACCGAGGC CCCGTTTCTG 
TCCTGCATTC TGTCCCCAGG AGACACCCTC TTTATACCTG CTAAGTACTG GCATTACGTG 
CGCTCCCTGG ACCTGAGCTT CTCTGTCAGC TTCTGGTGGT CATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Kdm8 ( XM_006230259.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006230321.1 Rattus norvegicus lysine demethylase 8 (Kdm8), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa23431
Clone ID Related Accession (Same CDS sequence)	XM_006230259.3
Accession Version	XM_006230259.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1152bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	lysine-specific demethylase 8 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006230259.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCAGAGG ACACTACAGA GCCCCTAGTG GGGCCCAGCA TCCTCTGGAA GGACCTCAGG 
GTGCTCCTGC CAGACACAGA GGAGGAGCTG AAGCTGGATC TCAGTGAGAA GGTGGACAGG 
AGCGTGGCTA CGCTGCTACG GCAGGCTTTG GGTCTGTTCT ATGAAGGCCG TTGGCAGAAG 
TGCCTGCAGG CCAGTGAGGC TGTCCTGGAC TACTCCTGGG AAAAGCTCAA CACTGGTCCC 
TGGCGAGATG TAGACAAGGA ATGGCGCCGG GTATATTCCT TCGGCTGCCT CCTGAAGACC 
CTGTGCCTGT GCCAGGCACC ACAGAAGGCC ACTGCTGTGG CTGAAGCACT GCGGGTGTGT 
GACATGGGCC TGTTGATGGG GGCAGCCATC CTTGGGGACA TTCTTCTCAA AGTTGCTACA 
GTCCTCCAGA CACATCTGCT CCCTAGAAAG CAGCCTGCCT GTGGCCCTCA CCAGGATCAG 
CCTGCTACCA AGAAGGCAAA GCATGATGCC AGCTCAACTC CTGATGTGGT ATTAGATCGG 
GAAGTGCCCA GGCTTCGCTG CCCACCTCTG CAGCACTTCA AGAAGCATTT TCTAGTTCCT 
GGGAGACCTG TGATCTTGGA AGGTGTGGCT GACCACTGGC CGTGCATGAA GAAGTGGAGT 
CTACAGTACA TCCAGGAGAT TGCTGGCTGC CGCACTGTCC CCGTGGAAGT GGGTTCAAGA 
TACACAGATG AAGACTGGTC CCAGACTCTC ATGACAGTCA ATGAGTTCAT CCACAAATAC 
ATTCTGAGCG AGGCAAAGGA TGTCGGGTAC CTTGCTCAAC ACCAGCTGTT CGACCAGATC 
CCAGAGTTGA AGCAGGACAT CAGCATCCCC GATTACTGTT GCCTGGGCAA TGGAGAAGAG 
GAAGAGATCA CTATCAATGC CTGGTTTGGT CCTCAAGGAA CCATCTCCCC ATTGCATCAG 
GACCCCCAGC AGAACTTCCT GGTCCAGGTT GATGTGGAAA ACCCCGACCT AGAGAAGTTC 
CCCAAGTTCA CCGAGGCCCC GTTTCTGTCC TGCATTCTGT CCCCAGGAGA CACCCTCTTT 
ATACCTGCTA AGTACTGGCA TTACGTGCGC TCCCTGGACC TGAGCTTCTC TGTCAGCTTC 
TGGTGGTCAT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006230321.1
CDS	1135..2286
Translation	MSEDTTEPLVGPSILWKDLRVLLPDTEEELKLDLSEKVDRSVATLLRQALGLFYEGRWQKCLQASEAVLDYSWEKLNTGPWRDVDKEWRRVYSFGCLLKTLCLCQAPQKATAVAEALRVCDMGLLMGAAILGDILLKVATVLQTHLLPRKQPACGPHQDQPATKKAKHDASSTPDVVLDREVPRLRCPPLQHFKKHFLVPGRPVILEGVADHWPCMKKWSLQYIQEIAGCRTVPVEVGSRYTDEDWSQTLMTVNEFIHKYILSEAKDVGYLAQHQLFDQIPELKQDISIPDYCCLGNGEEEEITINAWFGPQGTISPLHQDPQQNFLVQVDVENPDLEKFPKFTEAPFLSCILSPGDTLFIPAKYWHYVRSLDLSFSVSFWWS

Target ORF information:

RefSeq Version	XM_006230259.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus lysine demethylase 8 (Kdm8), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006230259.3

ORF Insert Sequence:

ATGTCAGAGG ACACTACAGA GCCCCTAGTG GGGCCCAGCA TCCTCTGGAA GGACCTCAGG 
GTGCTCCTGC CAGACACAGA GGAGGAGCTG AAGCTGGATC TCAGTGAGAA GGTGGACAGG 
AGCGTGGCTA CGCTGCTACG GCAGGCTTTG GGTCTGTTCT ATGAAGGCCG TTGGCAGAAG 
TGCCTGCAGG CCAGTGAGGC TGTCCTGGAC TACTCCTGGG AAAAGCTCAA CACTGGTCCC 
TGGCGAGATG TAGACAAGGA ATGGCGCCGG GTATATTCCT TCGGCTGCCT CCTGAAGACC 
CTGTGCCTGT GCCAGGCACC ACAGAAGGCC ACTGCTGTGG CTGAAGCACT GCGGGTGTGT 
GACATGGGCC TGTTGATGGG GGCAGCCATC CTTGGGGACA TTCTTCTCAA AGTTGCTACA 
GTCCTCCAGA CACATCTGCT CCCTAGAAAG CAGCCTGCCT GTGGCCCTCA CCAGGATCAG 
CCTGCTACCA AGAAGGCAAA GCATGATGCC AGCTCAACTC CTGATGTGGT ATTAGATCGG 
GAAGTGCCCA GGCTTCGCTG CCCACCTCTG CAGCACTTCA AGAAGCATTT TCTAGTTCCT 
GGGAGACCTG TGATCTTGGA AGGTGTGGCT GACCACTGGC CGTGCATGAA GAAGTGGAGT 
CTACAGTACA TCCAGGAGAT TGCTGGCTGC CGCACTGTCC CCGTGGAAGT GGGTTCAAGA 
TACACAGATG AAGACTGGTC CCAGACTCTC ATGACAGTCA ATGAGTTCAT CCACAAATAC 
ATTCTGAGCG AGGCAAAGGA TGTCGGGTAC CTTGCTCAAC ACCAGCTGTT CGACCAGATC 
CCAGAGTTGA AGCAGGACAT CAGCATCCCC GATTACTGTT GCCTGGGCAA TGGAGAAGAG 
GAAGAGATCA CTATCAATGC CTGGTTTGGT CCTCAAGGAA CCATCTCCCC ATTGCATCAG 
GACCCCCAGC AGAACTTCCT GGTCCAGGTT GATGTGGAAA ACCCCGACCT AGAGAAGTTC 
CCCAAGTTCA CCGAGGCCCC GTTTCTGTCC TGCATTCTGT CCCCAGGAGA CACCCTCTTT 
ATACCTGCTA AGTACTGGCA TTACGTGCGC TCCCTGGACC TGAGCTTCTC TGTCAGCTTC 
TGGTGGTCAT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Clipping of arginine-methylated histone tails by JMJD5 and JMJD7.
Proceedings of the National Academy of Sciences of the United States of America114(37)E7717-E7726(2017 Sep)
Liu H,Wang C,Lee S,Deng Y,Wither M,Oh S,Ning F,Dege C,Zhang Q,Liu X,Johnson AM,Zang J,Chen Z,Janknecht R,Hansen K,Marrack P,Li CY,Kappler JW,Hagman J,Zhang G

Histone lysine methylation dynamics: establishment, regulation, and biological impact.
Molecular cell48(4)491-507(2012 Nov)
Black JC,Van Rechem C,Whetstine JR

Differential proteome profiling of pleural effusions from lung cancer and benign inflammatory disease patients.
Biochimica et biophysica acta1824(4)692-700(2012 Apr)
Wang Z,Wang C,Huang X,Shen Y,Shen J,Ying K

KDM8, a H3K36me2 histone demethylase that acts in the cyclin A1 coding region to regulate cancer cell proliferation.
Proceedings of the National Academy of Sciences of the United States of America107(21)9671-6(2010 May)
Hsia DA,Tepper CG,Pochampalli MR,Hsia EY,Izumiya C,Huerta SB,Wright ME,Chen HW,Kung HJ,Izumiya Y

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Kdm8 cDNA ORF clone, Rattus norvegicus(Norway rat)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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