Tnip2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Tnip2
Entrez Gene ID	305451
Full Name	TNFAIP3 interacting protein 2
General protein information	Preferred Names TNFAIP3 interacting protein 2 Names TNFAIP3-interacting protein 2
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 14 Map Location: 14q21

mRNA and Protein(s)

mRNA	Protein	Name
NM_001024771.1	NP_001019942.1	TNFAIP3-interacting protein 2
XM_006251255.3	XP_006251317.1	TNFAIP3-interacting protein 2 isoform X1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	TNIP2	XP_517075.4
Danio rerio (zebrafish)	LOC564279	XP_692717.4
Canis lupus familiaris (dog)	TNIP2	XP_005618568.1
Mus musculus (house mouse)	Tnip2	NP_620703.1
Gallus gallus (chicken)	TNIP2	NP_001026337.1
Bos taurus (cattle)	TNIP2	NP_001231520.1
Rattus norvegicus (Norway rat)	Tnip2	NP_001019942.1
Xenopus tropicalis (tropical clawed frog)	tnip2	XP_002941000.1
Homo sapiens (human)	TNIP2	NP_077285.3

Gene Ontology
Bibliography

Related articles in PubMed

A20-binding inhibitor of nuclear factor-kappaB (NF-kappaB)-2 (ABIN-2) is an activator of inhibitor of NF-kappaB (IkappaB) kinase alpha (IKKalpha)-mediated NF-kappaB transcriptional activity.
Leotoing L, Chereau F, Baron S, Hube F, Valencia HJ, Bordereaux D, Demmers JA, Strouboulis J, Baud V
The Journal of biological chemistry286(37)32277-88(2011 Sep)

Ubiquitin binding mediates the NF-kappaB inhibitory potential of ABIN proteins.
Wagner S, Carpentier I, Rogov V, Kreike M, Ikeda F, L?hr F, Wu CJ, Ashwell JD, D?tsch V, Dikic I, Beyaert R
Oncogene27(26)3739-45(2008 Jun)

ABIN-2 is required for optimal activation of Erk MAP kinase in innate immune responses.
Papoutsopoulou S, Symons A, Tharmalingham T, Belich MP, Kaiser F, Kioussis D, O'Garra A, Tybulewicz V, Ley SC
Nature immunology7(6)606-15(2006 Jun)

ABIN-2 protects endothelial cells from death and has a role in the antiapoptotic effect of angiopoietin-1.
Tadros A, Hughes DP, Dunmore BJ, Brindle NP
Blood102(13)4407-9(2003 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Tnip2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Tnip2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa06615	NM_001024771.1 Latest version!	Rattus norvegicus TNFAIP3 interacting protein 2 (Tnip2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$188.30 $269.00
ORa36273	XM_006251255.3 Latest version!	Rattus norvegicus TNFAIP3 interacting protein 2 (Tnip2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Tnip2 ( NM_001024771.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001019942.1 Rattus norvegicus TNFAIP3 interacting protein 2 (Tnip2), mRNA.

Price & Availability↑

CloneID	ORa06615
Clone ID Related Accession (Same CDS sequence)	NM_001024771.1
Accession Version	NM_001024771.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 936bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-06
Organism	Rattus norvegicus(Norway rat)
Product	TNFAIP3-interacting protein 2
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC097956.1. On Jun 10, 2005 this sequence version replaced XM_223535.3. ##Evidence-Data-START## Transcript exon combination :: BC097956.1, BC085912.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGTCGTCTG GGGACGCAAG GTCTGGTAGA CAGGACGAGG CCCCGAGCGC GGCCTCAGCG 
CTCTGTGGCC TGTACCACGA GGCAGGCCAG CAACTACAGC TCCTGAAGGA TCAGCTGGCT 
GCGCGTGACG CCCTTATCGC GAGCCTCCGC ACCCGCCTCG CGGCTCTGGA AGGGCACACG 
GCACCATCAC TTGTGGACGC ACTTCTGGAT CAGGTGGAGC GCTTCCGTGA GCAGCTGCGG 
CGACAGGAGG ATGGTGCCTC GGAGTCCCAA CTGCGGCAGG AAGTTGAAAG ACTTACTGAG 
TGTCTAGAAG AAAAAGAGAG GGAGATGCAG CAGCTGATGA GCCAGCCTCA GCATGAGCAA 
GAGAAGGAGG TGGTCTTGCT TCGGAGAAGT GTGGTAGAGA AGGAAAAAGC CAGGGCGGCC 
AGTGACATTC TGTGCCGCTC CTTGACTGAT GAGACCCACC AACTGCGCAG GACATTGGCT 
GCCACTGCCC ACATGTGCCA ACATCTGGCC AAATGTCTGG ATGAGCGACA ACGTGTGCAG 
GGAGACGCTG GGGAGAAAAG CCCTGCTGAG CTAGAGCATA CAAGCAGGGA TACCTCTGGC 
CAGAGTGTTA TTAAGAAGTT ACAGGAAGAA AATCGACTGT TAAAACAGAA GGTGATTCAT 
GTGGAAGACC TCAATGCCAA GTGGCAGCGT TATGATGCAA GTAGGGATGA ATACGTGAAG 
GGGTTACATG CACAGCTGAA GAGGCGGCAG GTTCCTCTTG AGCCTGAGCT TATGAAGAAG 
GAGATTTCCC GGCTTAACAG ACAGTTGGAG GAGAAAATAA GTGACTGTGC CGAAGCAAAA 
CAGGAGCTGG CAGCCGTGAA GATGGCCCGG GACACTGCGC TGGAGCGAGT GCAGATGCTG 
GAGCAGCAGG TGTCCTCAGG CTCTGAGCAG CCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001019942.1
CDS	103..1038
Translation	MSSGDARSGRQDEAPSAASALCGLYHEAGQQLQLLKDQLAARDALIASLRTRLAALEGHTAPSLVDALLDQVERFREQLRRQEDGASESQLRQEVERLTECLEEKEREMQQLMSQPQHEQEKEVVLLRRSVVEKEKARAASDILCRSLTDETHQLRRTLAATAHMCQHLAKCLDERQRVQGDAGEKSPAELEHTSRDTSGQSVIKKLQEENRLLKQKVIHVEDLNAKWQRYDASRDEYVKGLHAQLKRRQVPLEPELMKKEISRLNRQLEEKISDCAEAKQELAAVKMARDTALERVQMLEQQVSSGSEQP

Target ORF information:

RefSeq Version	NM_001024771.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus TNFAIP3 interacting protein 2 (Tnip2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001024771.1

ORF Insert Sequence:

ATGTCGTCTG GGGACGCAAG GTCTGGTAGA CAGGACGAGG CCCCGAGCGC GGCCTCAGCG 
CTCTGTGGCC TGTACCACGA GGCAGGCCAG CAACTACAGC TCCTGAAGGA TCAGCTGGCT 
GCGCGTGACG CCCTTATCGC GAGCCTCCGC ACCCGCCTCG CGGCTCTGGA AGGGCACACG 
GCACCATCAC TTGTGGACGC ACTTCTGGAT CAGGTGGAGC GCTTCCGTGA GCAGCTGCGG 
CGACAGGAGG ATGGTGCCTC GGAGTCCCAA CTGCGGCAGG AAGTTGAAAG ACTTACTGAG 
TGTCTAGAAG AAAAAGAGAG GGAGATGCAG CAGCTGATGA GCCAGCCTCA GCATGAGCAA 
GAGAAGGAGG TGGTCTTGCT TCGGAGAAGT GTGGTAGAGA AGGAAAAAGC CAGGGCGGCC 
AGTGACATTC TGTGCCGCTC CTTGACTGAT GAGACCCACC AACTGCGCAG GACATTGGCT 
GCCACTGCCC ACATGTGCCA ACATCTGGCC AAATGTCTGG ATGAGCGACA ACGTGTGCAG 
GGAGACGCTG GGGAGAAAAG CCCTGCTGAG CTAGAGCATA CAAGCAGGGA TACCTCTGGC 
CAGAGTGTTA TTAAGAAGTT ACAGGAAGAA AATCGACTGT TAAAACAGAA GGTGATTCAT 
GTGGAAGACC TCAATGCCAA GTGGCAGCGT TATGATGCAA GTAGGGATGA ATACGTGAAG 
GGGTTACATG CACAGCTGAA GAGGCGGCAG GTTCCTCTTG AGCCTGAGCT TATGAAGAAG 
GAGATTTCCC GGCTTAACAG ACAGTTGGAG GAGAAAATAA GTGACTGTGC CGAAGCAAAA 
CAGGAGCTGG CAGCCGTGAA GATGGCCCGG GACACTGCGC TGGAGCGAGT GCAGATGCTG 
GAGCAGCAGG TGTCCTCAGG CTCTGAGCAG CCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Tnip2 ( XM_006251255.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006251317.1 Rattus norvegicus TNFAIP3 interacting protein 2 (Tnip2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa36273
Clone ID Related Accession (Same CDS sequence)	XM_006251255.3
Accession Version	XM_006251255.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1293bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	TNFAIP3-interacting protein 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005113.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006251255.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCGTCTG GGGACGCAAG GTCTGGTAGA CAGGACGAGG CCCCGAGCGC GGCCTCAGCG 
CTCTGTGGCC TGTACCACGA GGCAGGCCAG CAACTACAGC TCCTGAAGGA TCAGCTGGCT 
GCGCGTGACG CCCTTATCGC GAGCCTCCGC ACCCGCCTCG CGGCTCTGGA AGGGCACACG 
GCACCATCAC TTGTGGACGC ACTTCTGGAT CAGGTGGAGC GCTTCCGTGA GCAGCTGCGG 
CGACAGGAGG ATGGTGCCTC GGAGTCCCAA CTGCGGCAGG AAGTTGAAAG ACTTACTGAG 
TGTCTAGAAG AAAAAGAGAG GGAGATGCAG CAGCTGATGA GCCAGCCTCA GCATGAGCAA 
GAGAAGGAGG TGGTCTTGCT TCGGAGAAGT GTGGTAGAGA AGGAAAAAGC CAGGGCGGCC 
AGTGACATTC TGTGCCGCTC CTTGACTGAT GAGACCCACC AACTGCGCAG GACATTGGCT 
GCCACTGCCC ACATGTGCCA ACATCTGGCC AAATGTCTGG ATGAGCGACA ACGTGTGCAG 
GGAGACGCTG GGGAGAAAAG CCCTGCTGAG CTAGAGCATA CAAGCAGGGA TACCTCTGGC 
CAGAGTGTTA TTAAGAAGTT ACAGGAAGAA AATCGACTGT TAAAACAGAA GGTGATTCAT 
GTGGAAGACC TCAATGCCAA GTGGCAGCGT TATGATGCAA GTAGGGATGA ATACGTGAAG 
GGGTTACATG CACAGCTGAA GAGGCGGCAG GTTCCTCTTG AGCCTGAGCT TATGAAGAAG 
GAGATTTCCC GGCTTAACAG ACAGTTGGAG GAGAAAATAA GTGACTGTGC CGAAGCAAAA 
CAGGAGCTGG CAGCCGTGAA GATGGCCCGG GACACTGCGC TGGAGCGAGT GCAGATGCTG 
GAGCAGCAGA TTCTTGCTTA CAAGGATGAC TTCAAATCAG AAAGGGCAGA TCGGGAACGA 
GCTCATAGTA GGATTCAGGA GCTGGAGGAA AAGGTCATGT CCTTGATGTA CCAAGTTTCC 
CAGAGACAGG ACTCCCGGGA GCCAGGACCC TGTCGGATTC ATACGGGGAG CAAAACTGCC 
AAGTACTTAG AGATGGATGC ACTGGAGCAT GTGGCGCCGG GCGGCTGGAG GCCTGAGTCT 
AGGTCCCAAC AGATGGAACC TTCTGCAGAG GGTGGGCATG TCTGTACAAC CCAGAGAGGT 
CAGGGTGATC TTCAGTGTCC TCATTGCCTG CGGTGTTTCA GTGATGAGCA AGGCGAGGCA 
TTCCTCAGGC ACCTTTCTGA GTGCTGCCAA TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006251317.1
CDS	181..1473
Translation	MSSGDARSGRQDEAPSAASALCGLYHEAGQQLQLLKDQLAARDALIASLRTRLAALEGHTAPSLVDALLDQVERFREQLRRQEDGASESQLRQEVERLTECLEEKEREMQQLMSQPQHEQEKEVVLLRRSVVEKEKARAASDILCRSLTDETHQLRRTLAATAHMCQHLAKCLDERQRVQGDAGEKSPAELEHTSRDTSGQSVIKKLQEENRLLKQKVIHVEDLNAKWQRYDASRDEYVKGLHAQLKRRQVPLEPELMKKEISRLNRQLEEKISDCAEAKQELAAVKMARDTALERVQMLEQQILAYKDDFKSERADRERAHSRIQELEEKVMSLMYQVSQRQDSREPGPCRIHTGSKTAKYLEMDALEHVAPGGWRPESRSQQMEPSAEGGHVCTTQRGQGDLQCPHCLRCFSDEQGEAFLRHLSECCQ

Target ORF information:

RefSeq Version	XM_006251255.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus TNFAIP3 interacting protein 2 (Tnip2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006251255.3

ORF Insert Sequence:

ATGTCGTCTG GGGACGCAAG GTCTGGTAGA CAGGACGAGG CCCCGAGCGC GGCCTCAGCG 
CTCTGTGGCC TGTACCACGA GGCAGGCCAG CAACTACAGC TCCTGAAGGA TCAGCTGGCT 
GCGCGTGACG CCCTTATCGC GAGCCTCCGC ACCCGCCTCG CGGCTCTGGA AGGGCACACG 
GCACCATCAC TTGTGGACGC ACTTCTGGAT CAGGTGGAGC GCTTCCGTGA GCAGCTGCGG 
CGACAGGAGG ATGGTGCCTC GGAGTCCCAA CTGCGGCAGG AAGTTGAAAG ACTTACTGAG 
TGTCTAGAAG AAAAAGAGAG GGAGATGCAG CAGCTGATGA GCCAGCCTCA GCATGAGCAA 
GAGAAGGAGG TGGTCTTGCT TCGGAGAAGT GTGGTAGAGA AGGAAAAAGC CAGGGCGGCC 
AGTGACATTC TGTGCCGCTC CTTGACTGAT GAGACCCACC AACTGCGCAG GACATTGGCT 
GCCACTGCCC ACATGTGCCA ACATCTGGCC AAATGTCTGG ATGAGCGACA ACGTGTGCAG 
GGAGACGCTG GGGAGAAAAG CCCTGCTGAG CTAGAGCATA CAAGCAGGGA TACCTCTGGC 
CAGAGTGTTA TTAAGAAGTT ACAGGAAGAA AATCGACTGT TAAAACAGAA GGTGATTCAT 
GTGGAAGACC TCAATGCCAA GTGGCAGCGT TATGATGCAA GTAGGGATGA ATACGTGAAG 
GGGTTACATG CACAGCTGAA GAGGCGGCAG GTTCCTCTTG AGCCTGAGCT TATGAAGAAG 
GAGATTTCCC GGCTTAACAG ACAGTTGGAG GAGAAAATAA GTGACTGTGC CGAAGCAAAA 
CAGGAGCTGG CAGCCGTGAA GATGGCCCGG GACACTGCGC TGGAGCGAGT GCAGATGCTG 
GAGCAGCAGA TTCTTGCTTA CAAGGATGAC TTCAAATCAG AAAGGGCAGA TCGGGAACGA 
GCTCATAGTA GGATTCAGGA GCTGGAGGAA AAGGTCATGT CCTTGATGTA CCAAGTTTCC 
CAGAGACAGG ACTCCCGGGA GCCAGGACCC TGTCGGATTC ATACGGGGAG CAAAACTGCC 
AAGTACTTAG AGATGGATGC ACTGGAGCAT GTGGCGCCGG GCGGCTGGAG GCCTGAGTCT 
AGGTCCCAAC AGATGGAACC TTCTGCAGAG GGTGGGCATG TCTGTACAAC CCAGAGAGGT 
CAGGGTGATC TTCAGTGTCC TCATTGCCTG CGGTGTTTCA GTGATGAGCA AGGCGAGGCA 
TTCCTCAGGC ACCTTTCTGA GTGCTGCCAA TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A20-binding inhibitor of nuclear factor-kappaB (NF-kappaB)-2 (ABIN-2) is an activator of inhibitor of NF-kappaB (IkappaB) kinase alpha (IKKalpha)-mediated NF-kappaB transcriptional activity.
The Journal of biological chemistry286(37)32277-88(2011 Sep)
Leotoing L,Chereau F,Baron S,Hube F,Valencia HJ,Bordereaux D,Demmers JA,Strouboulis J,Baud V

Ubiquitin binding mediates the NF-kappaB inhibitory potential of ABIN proteins.
Oncogene27(26)3739-45(2008 Jun)
Wagner S,Carpentier I,Rogov V,Kreike M,Ikeda F,L?hr F,Wu CJ,Ashwell JD,D?tsch V,Dikic I,Beyaert R

ABIN-2 is required for optimal activation of Erk MAP kinase in innate immune responses.
Nature immunology7(6)606-15(2006 Jun)
Papoutsopoulou S,Symons A,Tharmalingham T,Belich MP,Kaiser F,Kioussis D,O'Garra A,Tybulewicz V,Ley SC

ABIN-2 protects endothelial cells from death and has a role in the antiapoptotic effect of angiopoietin-1.
Blood102(13)4407-9(2003 Dec)
Tadros A,Hughes DP,Dunmore BJ,Brindle NP

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Tnip2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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