Uck2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Uck2
Entrez Gene ID	304944
Full Name	uridine-cytidine kinase 2
Synonyms	Umpk
General protein information	Preferred Names uridine-cytidine kinase 2 Names uridine-cytidine kinase 2 UCK 2 cytidine monophosphokinase 2 uridine monophosphate kinase uridine monophosphokinase 2
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 13 Map Location: 13q24
Summary	rate-limiting enzyme of the salvage pathway in pyrimidine synthesis; converts uridine into uridine-59-mono-phosphate in the presence of ATP; may play a role in nerve regeneration and maturation [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_001102408.1	NP_001095878.1	uridine-cytidine kinase 2

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Uck2	NP_001095878.1
Gallus gallus (chicken)	UCK2	NP_001153543.1
	UCK2	XP_001086347.1
Canis lupus familiaris (dog)	UCK2	XP_005640995.1
Mus musculus (house mouse)	Uck2	NP_109649.1
Danio rerio (zebrafish)	uck2a	NP_001164538.1
Drosophila melanogaster (fruit fly)	CG6364	NP_001247281.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP003874	XP_003436642.1
Xenopus tropicalis (tropical clawed frog)	uck2	NP_001120241.1
Homo sapiens (human)	UCK2	NP_036606.2
Pan troglodytes (chimpanzee)	UCK2	XP_001174667.1
Bos taurus (cattle)	UCK2	NP_001179741.1

Gene Ontology
Bibliography

Related articles in PubMed

Gene and alternative splicing annotation with AIR.
Florea L, Di Francesco V, Miller J, Turner R, Yao A, Harris M, Walenz B, Mobarry C, Merkulov GV, Charlab R, Dew I, Deng Z, Istrail S, Li P, Sutton G
Genome research15(1)54-66(2005 Jan)

Structural basis for the specificity, catalysis, and regulation of human uridine-cytidine kinase.
Suzuki NN, Koizumi K, Fukushima M, Matsuda A, Inagaki F
Structure (London, England : 1993)12(5)751-64(2004 May)

Sensitivity of human cancer cells to the new anticancer ribo-nucleoside TAS-106 is correlated with expression of uridine-cytidine kinase 2.
Shimamoto Y, Koizumi K, Okabe H, Kazuno H, Murakami Y, Nakagawa F, Matsuda A, Sasaki T, Fukushima M
Japanese journal of cancer research : Gann93(7)825-33(2002 Jul)

Up-regulated uridine kinase gene identified by RLCS in the ventral horn after crush injury to rat sciatic nerves.
Yuh I, Yaoi T, Watanabe S, Okajima S, Hirasawa Y, Fushiki S
Biochemical and biophysical research communications266(1)104-9(1999 Dec)

Postnatal ontogeny of uridine kinase in the cerebellum, hypothalamus, and cerebral cortex of the rat.
Litteria M, Popoff CG
Neurochemical research10(1)63-75(1985 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Uck2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Uck2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa39876	NM_001102408.1 Latest version!	Rattus norvegicus uridine-cytidine kinase 2 (Uck2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Uck2 ( NM_001102408.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001095878.1 Rattus norvegicus uridine-cytidine kinase 2 (Uck2), mRNA.

Price & Availability↑

CloneID	ORa39876
Clone ID Related Accession (Same CDS sequence)	NM_001102408.1
Accession Version	NM_001102408.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 786bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-06-07
Organism	Rattus norvegicus(Norway rat)
Product	uridine-cytidine kinase 2
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AABR07021684.1 and AABR07021682.1. On Aug 22, 2007 this sequence version replaced XM_222855.4. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.

ATGGCCGGGG ACAGCGAGCA GACCCTGCAG AACCACCAGC AGCCCAACGG CGGCGAGCCC 
TTCCTGATCG GCGTGAGCGG GGGCACGGCC AGCGGGAAGT CTTCCGTGTG TGCTAAGATC 
GTCCAGCTTC TGGGGCAGAA TGAGGTGGAT TACCACCAGA AGCAGGTGGT CATCCTGAGC 
CAGGATAGCT TCTACCGAGT CCTCACTTCA GAGCAGAAGG CCAAAGCCCT GAAGGGCCAA 
TTCAACTTCG ATCACCCGGA TGCCTTTGAC AACGAACTGA TCTTCAAAAC ACTCAAAGAA 
ATCACCGAAG GAAAAACAGT TCAGATCCCT GTGTATGACT TCGTCTCCCA CTCACGGAAA 
GAGGAGACAG TCACCATCTA CCCCGCAGAT GTGGTGCTCT TTGAAGGGAT CCTAGCCTTC 
TATTCCCAGG AGGTCCGAGA CCTGTTCCAG ATGAAGCTTT TCGTGGACAC CGATGCAGAT 
ACCCGTCTGT CTCGCAGAGT TTTGAGGGAC ATCAGTGAAA GAGGGAGGGA CCTTGAGCAG 
ATTTTATCTC AGTACATTAC ATTCGTGAAA CCTGCCTTCG AGGAGTTCTG CTTGCCAAAG 
TTGGAGCTTA GACCAGTTCT TTTGGGAAGA TCTTTTGGGA AGGGTGTGGC CATCAACCTC 
ATCGTGCAGC ATATACAGGA CATCCTGAAC GGCGGGCTCT CCAAGCGGCA GACGAACGGC 
TATCTCAACG GCTATACCCC TTCCCGCAAG AGGCAGGCGT CAGAGTCCAG CAGCCGGCCA 
CATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001095878.1
CDS	446..1231
Translation	MAGDSEQTLQNHQQPNGGEPFLIGVSGGTASGKSSVCAKIVQLLGQNEVDYHQKQVVILSQDSFYRVLTSEQKAKALKGQFNFDHPDAFDNELIFKTLKEITEGKTVQIPVYDFVSHSRKEETVTIYPADVVLFEGILAFYSQEVRDLFQMKLFVDTDADTRLSRRVLRDISERGRDLEQILSQYITFVKPAFEEFCLPKLELRPVLLGRSFGKGVAINLIVQHIQDILNGGLSKRQTNGYLNGYTPSRKRQASESSSRPH

Target ORF information:

RefSeq Version	NM_001102408.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus uridine-cytidine kinase 2 (Uck2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001102408.1

ORF Insert Sequence:

ATGGCCGGGG ACAGCGAGCA GACCCTGCAG AACCACCAGC AGCCCAACGG CGGCGAGCCC 
TTCCTGATCG GCGTGAGCGG GGGCACGGCC AGCGGGAAGT CTTCCGTGTG TGCTAAGATC 
GTCCAGCTTC TGGGGCAGAA TGAGGTGGAT TACCACCAGA AGCAGGTGGT CATCCTGAGC 
CAGGATAGCT TCTACCGAGT CCTCACTTCA GAGCAGAAGG CCAAAGCCCT GAAGGGCCAA 
TTCAACTTCG ATCACCCGGA TGCCTTTGAC AACGAACTGA TCTTCAAAAC ACTCAAAGAA 
ATCACCGAAG GAAAAACAGT TCAGATCCCT GTGTATGACT TCGTCTCCCA CTCACGGAAA 
GAGGAGACAG TCACCATCTA CCCCGCAGAT GTGGTGCTCT TTGAAGGGAT CCTAGCCTTC 
TATTCCCAGG AGGTCCGAGA CCTGTTCCAG ATGAAGCTTT TCGTGGACAC CGATGCAGAT 
ACCCGTCTGT CTCGCAGAGT TTTGAGGGAC ATCAGTGAAA GAGGGAGGGA CCTTGAGCAG 
ATTTTATCTC AGTACATTAC ATTCGTGAAA CCTGCCTTCG AGGAGTTCTG CTTGCCAAAG 
TTGGAGCTTA GACCAGTTCT TTTGGGAAGA TCTTTTGGGA AGGGTGTGGC CATCAACCTC 
ATCGTGCAGC ATATACAGGA CATCCTGAAC GGCGGGCTCT CCAAGCGGCA GACGAACGGC 
TATCTCAACG GCTATACCCC TTCCCGCAAG AGGCAGGCGT CAGAGTCCAG CAGCCGGCCA 
CATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Gene and alternative splicing annotation with AIR.
Genome research15(1)54-66(2005 Jan)
Florea L,Di Francesco V,Miller J,Turner R,Yao A,Harris M,Walenz B,Mobarry C,Merkulov GV,Charlab R,Dew I,Deng Z,Istrail S,Li P,Sutton G

Structural basis for the specificity, catalysis, and regulation of human uridine-cytidine kinase.
Structure (London, England : 1993)12(5)751-64(2004 May)
Suzuki NN,Koizumi K,Fukushima M,Matsuda A,Inagaki F

Sensitivity of human cancer cells to the new anticancer ribo-nucleoside TAS-106 is correlated with expression of uridine-cytidine kinase 2.
Japanese journal of cancer research : Gann93(7)825-33(2002 Jul)
Shimamoto Y,Koizumi K,Okabe H,Kazuno H,Murakami Y,Nakagawa F,Matsuda A,Sasaki T,Fukushima M

Up-regulated uridine kinase gene identified by RLCS in the ventral horn after crush injury to rat sciatic nerves.
Biochemical and biophysical research communications266(1)104-9(1999 Dec)
Yuh I,Yaoi T,Watanabe S,Okajima S,Hirasawa Y,Fushiki S

Postnatal ontogeny of uridine kinase in the cerebellum, hypothalamus, and cerebral cortex of the rat.
Neurochemical research10(1)63-75(1985 Jan)
Litteria M,Popoff CG

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Uck2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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