Wdr81 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Wdr81
Entrez Gene ID	303312
Full Name	WD repeat domain 81
Synonyms	RGD1311334
General protein information	Preferred Names WD repeat domain 81 Names WD repeat-containing protein 81
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 10 Map Location: 10q24

mRNA and Protein(s)

mRNA	Protein	Name
NM_001134360.1	NP_001127832.1	WD repeat-containing protein 81

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Wdr81	NP_001127832.1
Homo sapiens (human)	WDR81	NP_001157281.1
Canis lupus familiaris (dog)	WDR81	XP_854000.2
Mus musculus (house mouse)	Wdr81	NP_620400.2
Gallus gallus (chicken)	WDR81	XP_004946596.1
Danio rerio (zebrafish)	LOC100333062	XP_005157714.1
Xenopus tropicalis (tropical clawed frog)	wdr81	XP_002937192.1
Drosophila melanogaster (fruit fly)	CG6734	NP_609535.1
Bos taurus (cattle)	WDR81	XP_005220210.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP007731	XP_317789.4
Pan troglodytes (chimpanzee)	WDR81	XP_003952981.1

Gene Ontology
Bibliography

Related articles in PubMed

The BEACH-containing protein WDR81 coordinates p62 and LC3C to promote aggrephagy.
Liu X, Li Y, Wang X, Xing R, Liu K, Gan Q, Tang C, Gao Z, Jian Y, Luo S, Guo W, Yang C
The Journal of cell biology216(5)1301-1320(2017 May)

A Genetic Screen Identifies a Critical Role for the WDR81-WDR91 Complex in the Trafficking and Degradation of Tetherin.
Rapiteanu R, Davis LJ, Williamson JC, Timms RT, Paul Luzio J, Lehner PJ
Traffic (Copenhagen, Denmark)17(8)940-58(2016 08)

Negative regulation of phosphatidylinositol 3-phosphate levels in early-to-late endosome conversion.
Liu K, Jian Y, Sun X, Yang C, Gao Z, Zhang Z, Liu X, Li Y, Xu J, Jing Y, Mitani S, He S, Yang C
The Journal of cell biology212(2)181-98(2016 Jan)

WDR81 is necessary for purkinje and photoreceptor cell survival.
Traka M, Millen KJ, Collins D, Elbaz B, Kidd GJ, Gomez CM, Popko B
The Journal of neuroscience : the official journal of the Society for Neuroscience33(16)6834-44(2013 Apr)

Docking motif-guided mapping of the interactome of protein phosphatase-1.
Hendrickx A, Beullens M, Ceulemans H, Den Abt T, Van Eynde A, Nicolaescu E, Lesage B, Bollen M
Chemistry & biology16(4)365-71(2009 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Wdr81 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Wdr81 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa02632	NM_001134360.1 Latest version!	Rattus norvegicus WD repeat domain 81 (Wdr81), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$951.30 $1359.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Wdr81 ( NM_001134360.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001127832.1 Rattus norvegicus WD repeat domain 81 (Wdr81), mRNA.

Price & Availability↑

CloneID	ORa02632
Clone ID Related Accession (Same CDS sequence)	NM_001134360.1
Accession Version	NM_001134360.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 5802bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-09-16
Organism	Rattus norvegicus(Norway rat)
Product	WD repeat-containing protein 81
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473948.1. On or before Aug 26, 2008 this sequence version replaced XM_001080687.1, XM_220710.4. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMN01906353 [ECO:0000348] ##Evidence-Data-END##

ATGGCCCAGG GGAGCAGAAG GCGGAAAGTG GTTCTTACAG CAGGGGCCGA GGGCTGCTCC 
TCCTCCTCAG GACCTGACAT GGAGGAGCTG CTCCGGTGCG CGGAGAGAGA TCTGAACATC 
GATGCCCGGC AGCTGGCCCT GGCGCCGGGG GGCACCCACG TGGTGGCCCT AGTGTCCACG 
CGTTGGTTAG CTAGTCTCCG GGAGCGCCGG CTGGGACCCT GTCCCCGGGC TGAGGGCCTG 
GGTGAAGCGG AAGTCAGGAC TCTACTGCAA CGTTCGGTAC AGAGGCTACC CCAGGGCTGG 
ACGCGAGTGG AGGTGCACGG GCTGCGGAAA CGGAGACTGT CCTACCCGCT GAGCAGAGTC 
TTGCCCTTTG AGGAGGGGTC CTGTAGCCCT GAGACTCTCA CTCGTTTCAT GCAGGAGGTG 
GCTGCCCAGA ATTACCGGAA CCTGTGGCGC CATGCATATC ACACTTATGG GCAGCCCTAT 
AGCCACAGCA CTGCCCCCTC AGCTATACCT GCCCTAGACT CTATCAGACA AGCTCTACAG 
AGGGTCTATG GATGCACCTT CCTGCCAGTG GGTGAATCCA TGCAATGTCT ATCAAATGTC 
AGGGATGGGC CCTCTCGGGG CAGCTCTGCC TGCCCCAGCC TTTTGCGAGC TGAGGCCCTG 
CTGGAGTCAC CCGAGATGCT CTATGTGGTA CACCCTTATG TGCAGTTCTC CCTGCATGAT 
GTAGTTACCT TCAGCCCTGC CAAACTGACC AACAGTCAAG CCAAGGTGCT TTTCATTCTC 
TTCCGTGTTC TGAGGGCCAT GGATGCCTGT CACCGCCAGG GTCTGGCCTG TGGGGCCCTG 
TCTTTGCACC ACATCGCTGT AGACGAGAAG CTTTGCAGCG AGCTCCGGCT GGACCTGAGT 
GCTTATGAGA TGCCTTCTGA GGATGAGAAT CAGGAGGTCT CTGAAGAGAA AGACAGGACA 
GGTGTTAAGT CTGAAAAAGA CGGGGAAGGG AGACCTGGGT GTCCCACCTG CCAGAAAGAA 
CTTAGGGGCC TTGTGCTAGA CTGGGTCCAT GGCCGCGTCA GCAACTTCTA CTACCTCATG 
CAGCTGAATC GGTTGGCAGG TCGACGGCAG GGGGATCCCA ACTATCACCC AGTGCTGCCC 
TGGGTGGTGG ATTTTACCAC GCCTTACGGG CGCTTCCGAG ACCTTCGTAA ATCCAAGTTC 
CGACTCAACA AGGGAGATAA GCAATTGGAC TTCACCTATG AGATGACACG GCAGGCATTT 
GTAGCCGGTG GTGCGGGAAG TGGGGAGCCA CTTCATGTTC CTCACCACAT CTCCGATGTG 
CTCTCTGACA TCACATACTA TGTATACAAG GCCCGTCGCA CACCCCGATC GGTGCTCTGT 
GGACATGTCC GGGCACAGTG GGAGCCCCAC GAGTATCCTG CCACCATGGA GCGGATGCAG 
ACCTGGACAC CAGATGAGTG CATACCCGAA TTCTACACGG ATCCCTCTAT CTTTTGCTCC 
ATCCACCCTG ACATGCCTGA CCTGGACGTG CCAGCCTGGT GCAGTTCTAA CCAGGAATTT 
GTGACTGCCC ATAGAGCACT GCTGGAGAGC TGGGAGGTGT CCCAAGACCT GCATCATTGG 
ATTGACCTTA CTTTTGGCTA CAAACTCCAG GGCAAAGAAG CTGTGAAGGA GAAGAATGTG 
TGTCTGCACC TGGTGGATGC TCACACCCAT CTGACCAGCT ATGGCGTGGT ACAGCTGTTT 
GATCAGCCAC ACCCCCAACG CCTGGCTGGG GCTCCTGCCC TGGCCCCTGA ACCTCCACTC 
ATACCCCGGC TGTTGGTCCA GCCTATTCAG GAGGCCACGG GCCAGGAGGA CATCTCAGGA 
CAACTTATTA ATGGTGCGGG CAGGCATGTT GTAGAGGTCA CTCCATGTGA GAGTGGCTGG 
ACTAGAGAGA GGCCCACGGC AGGGGAAGAT GACTTAGAAC AGGCTACAGA AGCTCTGGAT 
TCCATTTCCA TCCCTGGGAA AGCAGGTGAC CAGCCAGGCT CTTCCTCCAG TCAGGCCTCA 
CCTGGTCTGT TGCCTTTTTC TGCACCCTCA GGCTCTCGGC CAGGCCGCAG GAGCAAAGCT 
ACCGGGTTGG ACTCCGGGGA GGGCGACGAG GGCAAGATTG TTCTTCCAGA AGGCTTCAGT 
CCCATACAGG CCTTGGAAGA GCTAGAGAAA GTGGGTAACT TCCTGGCCAG AGGCCTAGGG 
AGCCAGTTGG AGGAACCCGA GAAGCCTCAA GCCCAGCCAC CTGTGTACCT GCAGAGTCTC 
TTCCATCGAG ACATGCAGGT GCTGGGTGTC CTGTTGGCTG AGATGGTGTT TGCCACCAGG 
GTCCGGATAC TGCAGCCCGA TGCACCTTTG TGGGTACGCT TTGAGGCTGT TAGGGGCCTC 
TGCACACGCC ACTCCAAGGA CATCCCCGTG TCTCTGCAGC CTGTGCTGGA CACACTCCTA 
CAGCTGAGTG GACCCAAAAG TCCCTTAGTG GTGAAGAAGG GCAAGCTAGA CCCACTGTTT 
GAGTACAGGC CTGTTTCCCA AGGATTGCCC CCACCCAGCC CAGCTCAGCT CCTCAGTCCC 
TTCAGCTCTG TGGTCCCCTT CCCTACCTAC TTCCCAGCGC TGCACAAGTT CATTCTTTTA 
TATCAGGCCC GGCGTGTGGA GGATGAGGTC CAGGGACGGG AGCTGGTGTT TGCTCTATGG 
CAGCAGCTGG GTGCCGTGTT AAACGAAATC ACTCCCGAGG GCTTGGAGAT CCTCCTGCCT 
TTTGTGCTGT CACTCATGTC AGAGGAGCAC ACGGCTGTGT ACACAGCCTG GTACCTATTT 
GAACCTGTTG CCAAGGCCCT GGGCCCCAAA AATACCATTA AGTACCTCCT GAAGCCTCTC 
ATTGGTGCCT ATGAGAACCC CTGCCGCCTG CATGGCCGCT TCTACCTGTA CACTGACTGT 
TTTGTAGCCC AGTTGGTGGT GCGGTTGGGC TTGCAGGCCT TCCTTATCCA CCTGCTGCCC 
CACGTCCTAC AGGTACTGGC TGGGGTGGAG GCCTCCCAAG AGGAGGGCAA AGGCCTGGTT 
GGGACCACTG AGGATGAGGA AAACGAGCTC CCAGTGCCTG GGCCTGGCTC CTGTGCCTTT 
GGGGAGGAGA TTCAAATGGG TGGACAGCCG GCTGCTTCCT CAGGACTGGG GCTCCCAGAC 
TACAGGTCAG GCGTCAGCTT CCATGACCAG GCTGACCTGC CAGACACCGA GGACTTCCAA 
GCTGGACTCT ATGTGGCCGA GTCTCCACAG CCCCAGGAGG CTGAGGCCGT GAGCCTGGGC 
CAGCTGAGCG ACAAGAGCAG CACTAGTGAA GCCTCACAGG GCGAGGAGAG GGGTGGGGAT 
GATGGGGGTG CCCCTGTGGA CAAGAACAGC GTGAAGTCAG GGGACAGCAG CCAGGACTTG 
AAGCAAAGTG AAGGCTCTGA GGAAGAGGAG GAGGAGGAGG AAGGCTGTGT GGTGTTGGAG 
GAGGAGGAGC AGGATGAAGT CACAGGAACA TCTGAGCTCA CTCTGTCTGA CACAATACTG 
TCCATGGAGA CGGTTGTGGC TCCCGGCGAT GGGAGAGACA GAGAAGAGGA AGAGGAGCCC 
CTGCCAGAGC AGACAGAGGG CAAAGAGCAG AAGATCCTCC TTGATACAGC CTGCAAGATG 
GTCCGCTGGC TGTCCGCCAA GCTTGGCCCC ACTGTAGCCT CTCGCCACGT GGCCCGGAAC 
CTGTTGCGCC TGCTGACATC TTGTTATGTT GGGCCCACTA GGCAGCAGTT CACAGTCAGC 
TGTGATGACA GCCCCCCACT GAACGCCGGC AACATCTACC AGAAGAGGCC AGTACTAGGT 
GACATCGTGT CCGGGCCTGT GCTCAGCTGT CTTCTCCATA TTGCCCACCT ATATGGAGAA 
CCCGTTCTCA CCTACCAGTA CCTGCCCTAC ATCAGCTACC TGGTAGCCCC GGGGAGCAAC 
TCAAGCCCCA GCCGACTGAA CAGCCGCAAG GAGGCCGGGC TGCTGGCTGC GGTGACACTG 
ACTCAGAAAA TCATCGTATA CCTCTCCGAC ACTACCCTCA TGGACATTCT GCCCCGCATT 
AGCCACGAGG TCTTGCTGCC TGTGCTCAGC TTCCTCACCT CCTTTGTTAC AGGGTTCCCA 
AGCGGGGCCC AGGCCCGGAC TGTCCTGTGT GTGAAGACCA TTAGTCTAAT TGCCCTCATC 
TGCCTGCGCA TCGGACAGGA GATGGTCCAG CAGCACCTCA GTGAGCCGGT GGCCACCTTC 
TTTCAAGTCT TCTCTCATCT GCATGAGCTT CGGCAGCAGG ATCTGCAGCT GGATCTCAAG 
GGCTGTACTG AGGGCCAACT GCCAGAGGCA ACCTTCTCTG ATGGGCAGCG ACGGCCAGTG 
GACCCCACCC TGCTGGAGGA GCTGCAGAAG GTGTTCACCC TGGAAATGGC GTACACAATC 
TACGTACCTT TCTCCTGCCT GTTGGGTGAC ATCATCCGGA AAATTATCCC CAACCACGAG 
TTGGTCGGGG AGCTGGCAGG GCTATATCTG GAGAGCATGA GCCCGAGCTC TCTTCGAAAC 
CCAGCCAGCA TGGAACCCGT CACGCCTAGT GCTGGCCCTG AATGGAACCC TCAGAGTGGG 
AGCTGTCTCC AGGATGATGG CCACTCGGGG ACCTTTGGGA GTGTCCTGGT TGGAAATCGC 
ATCCAGATCC CCGACTCTCA GCCCCAGAGT TCCGGGCCAC TGGGCTCCAT CTCTGGAGTG 
GGTAGTGGAG GCCTCAGCAG CAGGAATGAA GACAATGCTC TGAAGCGGGA GCTGCCCCGG 
AGTGCCCACG GCCTGAGCGG GAACTGGCTA GCATACTGGC AATACGAGAT CGGTGTGAGC 
CAGCAGGATG CCCACTTCCA CTTCCACCAG ATCCGCCTGC AGAGCTTTCC AGGCCACACC 
GGGGCTGTCA AGTGTGTGGC CGCCCTGAGC AGTGAAGACT TCTTTCTGAG TGGCAGCAAG 
GACCGTACGG TGCGTCTTTG GCCACTGTAC AACTATGGGG ATGGGACCAG TGAGACGGCT 
CCCCGTCTCA TCTACGCCCA GCACCGCAAA AGTGTCTTCT ACGTGGGCCA GCTTGAGGCC 
CCGCAGTATG TGGTGAGCTG TGATGGGGCA GTGCACGTCT GGGACCCCTT CACAGGGAAG 
ACCCTTCGCA CAGTGGATCC TTCAGACAGC CGGGTGCCCC TGACTGCTGT AGCTGTCATG 
CCTGCCCCCC ACACCAGCAT CACCATGGCC AGCTCTGACT CCACCCTGCG CTTTGTGGAT 
TGCAGGAAGC CTGGCTTGCA GCATGAGTTC CGACTGGGTG GAGGGCTGAA CCCTGGGCTT 
GTTCGCTCCT TGGCTGTCAG CCCCAGTGGC CGGAGTGTTG TGGCTGGCTT CTCCTCTGGC 
TTCATGGTGC TTCTAGATAC CCGCACGGGC CTGGTTCTCC GAGGCTGGCC GGCCCATGAA 
GGGGACATTC TACAGATCAA GGCTGTAGAG GGCAGTGTGA TAGTCAGCTC CTCTTCCGAC 
CATTCCTTGA CTGTTTGGAA GGAGCTGGAG CAGAAGCCCA CGCACCACTA CAAGTCAGCA 
TCGGACCCAA TCCACACCTT CGACCTGTAC GGCAGCGAGG TGGTCACTGG CACTGTGGCC 
AACAAGATTG GTGTCTGTTC CCTGCTTGAA CCACCCTCTC AGGCCACCAC AAAGCTCAGT 
TCCGAGAACT TCCGTGGTAC ACTCACCAGT CTGGCTTTGC TGCCCACGAA ACGCCACCTC 
CTGCTGGGCT CTGACAATGG CATCATCCGC CTCCTGGCAT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001127832.1
CDS	211..6012
Translation	MAQGSRRRKVVLTAGAEGCSSSSGPDMEELLRCAERDLNIDARQLALAPGGTHVVALVSTRWLASLRERRLGPCPRAEGLGEAEVRTLLQRSVQRLPQGWTRVEVHGLRKRRLSYPLSRVLPFEEGSCSPETLTRFMQEVAAQNYRNLWRHAYHTYGQPYSHSTAPSAIPALDSIRQALQRVYGCTFLPVGESMQCLSNVRDGPSRGSSACPSLLRAEALLESPEMLYVVHPYVQFSLHDVVTFSPAKLTNSQAKVLFILFRVLRAMDACHRQGLACGALSLHHIAVDEKLCSELRLDLSAYEMPSEDENQEVSEEKDRTGVKSEKDGEGRPGCPTCQKELRGLVLDWVHGRVSNFYYLMQLNRLAGRRQGDPNYHPVLPWVVDFTTPYGRFRDLRKSKFRLNKGDKQLDFTYEMTRQAFVAGGAGSGEPLHVPHHISDVLSDITYYVYKARRTPRSVLCGHVRAQWEPHEYPATMERMQTWTPDECIPEFYTDPSIFCSIHPDMPDLDVPAWCSSNQEFVTAHRALLESWEVSQDLHHWIDLTFGYKLQGKEAVKEKNVCLHLVDAHTHLTSYGVVQLFDQPHPQRLAGAPALAPEPPLIPRLLVQPIQEATGQEDISGQLINGAGRHVVEVTPCESGWTRERPTAGEDDLEQATEALDSISIPGKAGDQPGSSSSQASPGLLPFSAPSGSRPGRRSKATGLDSGEGDEGKIVLPEGFSPIQALEELEKVGNFLARGLGSQLEEPEKPQAQPPVYLQSLFHRDMQVLGVLLAEMVFATRVRILQPDAPLWVRFEAVRGLCTRHSKDIPVSLQPVLDTLLQLSGPKSPLVVKKGKLDPLFEYRPVSQGLPPPSPAQLLSPFSSVVPFPTYFPALHKFILLYQARRVEDEVQGRELVFALWQQLGAVLNEITPEGLEILLPFVLSLMSEEHTAVYTAWYLFEPVAKALGPKNTIKYLLKPLIGAYENPCRLHGRFYLYTDCFVAQLVVRLGLQAFLIHLLPHVLQVLAGVEASQEEGKGLVGTTEDEENELPVPGPGSCAFGEEIQMGGQPAASSGLGLPDYRSGVSFHDQADLPDTEDFQAGLYVAESPQPQEAEAVSLGQLSDKSSTSEASQGEERGGDDGGAPVDKNSVKSGDSSQDLKQSEGSEEEEEEEEGCVVLEEEEQDEVTGTSELTLSDTILSMETVVAPGDGRDREEEEEPLPEQTEGKEQKILLDTACKMVRWLSAKLGPTVASRHVARNLLRLLTSCYVGPTRQQFTVSCDDSPPLNAGNIYQKRPVLGDIVSGPVLSCLLHIAHLYGEPVLTYQYLPYISYLVAPGSNSSPSRLNSRKEAGLLAAVTLTQKIIVYLSDTTLMDILPRISHEVLLPVLSFLTSFVTGFPSGAQARTVLCVKTISLIALICLRIGQEMVQQHLSEPVATFFQVFSHLHELRQQDLQLDLKGCTEGQLPEATFSDGQRRPVDPTLLEELQKVFTLEMAYTIYVPFSCLLGDIIRKIIPNHELVGELAGLYLESMSPSSLRNPASMEPVTPSAGPEWNPQSGSCLQDDGHSGTFGSVLVGNRIQIPDSQPQSSGPLGSISGVGSGGLSSRNEDNALKRELPRSAHGLSGNWLAYWQYEIGVSQQDAHFHFHQIRLQSFPGHTGAVKCVAALSSEDFFLSGSKDRTVRLWPLYNYGDGTSETAPRLIYAQHRKSVFYVGQLEAPQYVVSCDGAVHVWDPFTGKTLRTVDPSDSRVPLTAVAVMPAPHTSITMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRSLAVSPSGRSVVAGFSSGFMVLLDTRTGLVLRGWPAHEGDILQIKAVEGSVIVSSSSDHSLTVWKELEQKPTHHYKSASDPIHTFDLYGSEVVTGTVANKIGVCSLLEPPSQATTKLSSENFRGTLTSLALLPTKRHLLLGSDNGIIRLLA

Target ORF information:

RefSeq Version	NM_001134360.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus WD repeat domain 81 (Wdr81), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001134360.1

ORF Insert Sequence:

ATGGCCCAGG GGAGCAGAAG GCGGAAAGTG GTTCTTACAG CAGGGGCCGA GGGCTGCTCC 
TCCTCCTCAG GACCTGACAT GGAGGAGCTG CTCCGGTGCG CGGAGAGAGA TCTGAACATC 
GATGCCCGGC AGCTGGCCCT GGCGCCGGGG GGCACCCACG TGGTGGCCCT AGTGTCCACG 
CGTTGGTTAG CTAGTCTCCG GGAGCGCCGG CTGGGACCCT GTCCCCGGGC TGAGGGCCTG 
GGTGAAGCGG AAGTCAGGAC TCTACTGCAA CGTTCGGTAC AGAGGCTACC CCAGGGCTGG 
ACGCGAGTGG AGGTGCACGG GCTGCGGAAA CGGAGACTGT CCTACCCGCT GAGCAGAGTC 
TTGCCCTTTG AGGAGGGGTC CTGTAGCCCT GAGACTCTCA CTCGTTTCAT GCAGGAGGTG 
GCTGCCCAGA ATTACCGGAA CCTGTGGCGC CATGCATATC ACACTTATGG GCAGCCCTAT 
AGCCACAGCA CTGCCCCCTC AGCTATACCT GCCCTAGACT CTATCAGACA AGCTCTACAG 
AGGGTCTATG GATGCACCTT CCTGCCAGTG GGTGAATCCA TGCAATGTCT ATCAAATGTC 
AGGGATGGGC CCTCTCGGGG CAGCTCTGCC TGCCCCAGCC TTTTGCGAGC TGAGGCCCTG 
CTGGAGTCAC CCGAGATGCT CTATGTGGTA CACCCTTATG TGCAGTTCTC CCTGCATGAT 
GTAGTTACCT TCAGCCCTGC CAAACTGACC AACAGTCAAG CCAAGGTGCT TTTCATTCTC 
TTCCGTGTTC TGAGGGCCAT GGATGCCTGT CACCGCCAGG GTCTGGCCTG TGGGGCCCTG 
TCTTTGCACC ACATCGCTGT AGACGAGAAG CTTTGCAGCG AGCTCCGGCT GGACCTGAGT 
GCTTATGAGA TGCCTTCTGA GGATGAGAAT CAGGAGGTCT CTGAAGAGAA AGACAGGACA 
GGTGTTAAGT CTGAAAAAGA CGGGGAAGGG AGACCTGGGT GTCCCACCTG CCAGAAAGAA 
CTTAGGGGCC TTGTGCTAGA CTGGGTCCAT GGCCGCGTCA GCAACTTCTA CTACCTCATG 
CAGCTGAATC GGTTGGCAGG TCGACGGCAG GGGGATCCCA ACTATCACCC AGTGCTGCCC 
TGGGTGGTGG ATTTTACCAC GCCTTACGGG CGCTTCCGAG ACCTTCGTAA ATCCAAGTTC 
CGACTCAACA AGGGAGATAA GCAATTGGAC TTCACCTATG AGATGACACG GCAGGCATTT 
GTAGCCGGTG GTGCGGGAAG TGGGGAGCCA CTTCATGTTC CTCACCACAT CTCCGATGTG 
CTCTCTGACA TCACATACTA TGTATACAAG GCCCGTCGCA CACCCCGATC GGTGCTCTGT 
GGACATGTCC GGGCACAGTG GGAGCCCCAC GAGTATCCTG CCACCATGGA GCGGATGCAG 
ACCTGGACAC CAGATGAGTG CATACCCGAA TTCTACACGG ATCCCTCTAT CTTTTGCTCC 
ATCCACCCTG ACATGCCTGA CCTGGACGTG CCAGCCTGGT GCAGTTCTAA CCAGGAATTT 
GTGACTGCCC ATAGAGCACT GCTGGAGAGC TGGGAGGTGT CCCAAGACCT GCATCATTGG 
ATTGACCTTA CTTTTGGCTA CAAACTCCAG GGCAAAGAAG CTGTGAAGGA GAAGAATGTG 
TGTCTGCACC TGGTGGATGC TCACACCCAT CTGACCAGCT ATGGCGTGGT ACAGCTGTTT 
GATCAGCCAC ACCCCCAACG CCTGGCTGGG GCTCCTGCCC TGGCCCCTGA ACCTCCACTC 
ATACCCCGGC TGTTGGTCCA GCCTATTCAG GAGGCCACGG GCCAGGAGGA CATCTCAGGA 
CAACTTATTA ATGGTGCGGG CAGGCATGTT GTAGAGGTCA CTCCATGTGA GAGTGGCTGG 
ACTAGAGAGA GGCCCACGGC AGGGGAAGAT GACTTAGAAC AGGCTACAGA AGCTCTGGAT 
TCCATTTCCA TCCCTGGGAA AGCAGGTGAC CAGCCAGGCT CTTCCTCCAG TCAGGCCTCA 
CCTGGTCTGT TGCCTTTTTC TGCACCCTCA GGCTCTCGGC CAGGCCGCAG GAGCAAAGCT 
ACCGGGTTGG ACTCCGGGGA GGGCGACGAG GGCAAGATTG TTCTTCCAGA AGGCTTCAGT 
CCCATACAGG CCTTGGAAGA GCTAGAGAAA GTGGGTAACT TCCTGGCCAG AGGCCTAGGG 
AGCCAGTTGG AGGAACCCGA GAAGCCTCAA GCCCAGCCAC CTGTGTACCT GCAGAGTCTC 
TTCCATCGAG ACATGCAGGT GCTGGGTGTC CTGTTGGCTG AGATGGTGTT TGCCACCAGG 
GTCCGGATAC TGCAGCCCGA TGCACCTTTG TGGGTACGCT TTGAGGCTGT TAGGGGCCTC 
TGCACACGCC ACTCCAAGGA CATCCCCGTG TCTCTGCAGC CTGTGCTGGA CACACTCCTA 
CAGCTGAGTG GACCCAAAAG TCCCTTAGTG GTGAAGAAGG GCAAGCTAGA CCCACTGTTT 
GAGTACAGGC CTGTTTCCCA AGGATTGCCC CCACCCAGCC CAGCTCAGCT CCTCAGTCCC 
TTCAGCTCTG TGGTCCCCTT CCCTACCTAC TTCCCAGCGC TGCACAAGTT CATTCTTTTA 
TATCAGGCCC GGCGTGTGGA GGATGAGGTC CAGGGACGGG AGCTGGTGTT TGCTCTATGG 
CAGCAGCTGG GTGCCGTGTT AAACGAAATC ACTCCCGAGG GCTTGGAGAT CCTCCTGCCT 
TTTGTGCTGT CACTCATGTC AGAGGAGCAC ACGGCTGTGT ACACAGCCTG GTACCTATTT 
GAACCTGTTG CCAAGGCCCT GGGCCCCAAA AATACCATTA AGTACCTCCT GAAGCCTCTC 
ATTGGTGCCT ATGAGAACCC CTGCCGCCTG CATGGCCGCT TCTACCTGTA CACTGACTGT 
TTTGTAGCCC AGTTGGTGGT GCGGTTGGGC TTGCAGGCCT TCCTTATCCA CCTGCTGCCC 
CACGTCCTAC AGGTACTGGC TGGGGTGGAG GCCTCCCAAG AGGAGGGCAA AGGCCTGGTT 
GGGACCACTG AGGATGAGGA AAACGAGCTC CCAGTGCCTG GGCCTGGCTC CTGTGCCTTT 
GGGGAGGAGA TTCAAATGGG TGGACAGCCG GCTGCTTCCT CAGGACTGGG GCTCCCAGAC 
TACAGGTCAG GCGTCAGCTT CCATGACCAG GCTGACCTGC CAGACACCGA GGACTTCCAA 
GCTGGACTCT ATGTGGCCGA GTCTCCACAG CCCCAGGAGG CTGAGGCCGT GAGCCTGGGC 
CAGCTGAGCG ACAAGAGCAG CACTAGTGAA GCCTCACAGG GCGAGGAGAG GGGTGGGGAT 
GATGGGGGTG CCCCTGTGGA CAAGAACAGC GTGAAGTCAG GGGACAGCAG CCAGGACTTG 
AAGCAAAGTG AAGGCTCTGA GGAAGAGGAG GAGGAGGAGG AAGGCTGTGT GGTGTTGGAG 
GAGGAGGAGC AGGATGAAGT CACAGGAACA TCTGAGCTCA CTCTGTCTGA CACAATACTG 
TCCATGGAGA CGGTTGTGGC TCCCGGCGAT GGGAGAGACA GAGAAGAGGA AGAGGAGCCC 
CTGCCAGAGC AGACAGAGGG CAAAGAGCAG AAGATCCTCC TTGATACAGC CTGCAAGATG 
GTCCGCTGGC TGTCCGCCAA GCTTGGCCCC ACTGTAGCCT CTCGCCACGT GGCCCGGAAC 
CTGTTGCGCC TGCTGACATC TTGTTATGTT GGGCCCACTA GGCAGCAGTT CACAGTCAGC 
TGTGATGACA GCCCCCCACT GAACGCCGGC AACATCTACC AGAAGAGGCC AGTACTAGGT 
GACATCGTGT CCGGGCCTGT GCTCAGCTGT CTTCTCCATA TTGCCCACCT ATATGGAGAA 
CCCGTTCTCA CCTACCAGTA CCTGCCCTAC ATCAGCTACC TGGTAGCCCC GGGGAGCAAC 
TCAAGCCCCA GCCGACTGAA CAGCCGCAAG GAGGCCGGGC TGCTGGCTGC GGTGACACTG 
ACTCAGAAAA TCATCGTATA CCTCTCCGAC ACTACCCTCA TGGACATTCT GCCCCGCATT 
AGCCACGAGG TCTTGCTGCC TGTGCTCAGC TTCCTCACCT CCTTTGTTAC AGGGTTCCCA 
AGCGGGGCCC AGGCCCGGAC TGTCCTGTGT GTGAAGACCA TTAGTCTAAT TGCCCTCATC 
TGCCTGCGCA TCGGACAGGA GATGGTCCAG CAGCACCTCA GTGAGCCGGT GGCCACCTTC 
TTTCAAGTCT TCTCTCATCT GCATGAGCTT CGGCAGCAGG ATCTGCAGCT GGATCTCAAG 
GGCTGTACTG AGGGCCAACT GCCAGAGGCA ACCTTCTCTG ATGGGCAGCG ACGGCCAGTG 
GACCCCACCC TGCTGGAGGA GCTGCAGAAG GTGTTCACCC TGGAAATGGC GTACACAATC 
TACGTACCTT TCTCCTGCCT GTTGGGTGAC ATCATCCGGA AAATTATCCC CAACCACGAG 
TTGGTCGGGG AGCTGGCAGG GCTATATCTG GAGAGCATGA GCCCGAGCTC TCTTCGAAAC 
CCAGCCAGCA TGGAACCCGT CACGCCTAGT GCTGGCCCTG AATGGAACCC TCAGAGTGGG 
AGCTGTCTCC AGGATGATGG CCACTCGGGG ACCTTTGGGA GTGTCCTGGT TGGAAATCGC 
ATCCAGATCC CCGACTCTCA GCCCCAGAGT TCCGGGCCAC TGGGCTCCAT CTCTGGAGTG 
GGTAGTGGAG GCCTCAGCAG CAGGAATGAA GACAATGCTC TGAAGCGGGA GCTGCCCCGG 
AGTGCCCACG GCCTGAGCGG GAACTGGCTA GCATACTGGC AATACGAGAT CGGTGTGAGC 
CAGCAGGATG CCCACTTCCA CTTCCACCAG ATCCGCCTGC AGAGCTTTCC AGGCCACACC 
GGGGCTGTCA AGTGTGTGGC CGCCCTGAGC AGTGAAGACT TCTTTCTGAG TGGCAGCAAG 
GACCGTACGG TGCGTCTTTG GCCACTGTAC AACTATGGGG ATGGGACCAG TGAGACGGCT 
CCCCGTCTCA TCTACGCCCA GCACCGCAAA AGTGTCTTCT ACGTGGGCCA GCTTGAGGCC 
CCGCAGTATG TGGTGAGCTG TGATGGGGCA GTGCACGTCT GGGACCCCTT CACAGGGAAG 
ACCCTTCGCA CAGTGGATCC TTCAGACAGC CGGGTGCCCC TGACTGCTGT AGCTGTCATG 
CCTGCCCCCC ACACCAGCAT CACCATGGCC AGCTCTGACT CCACCCTGCG CTTTGTGGAT 
TGCAGGAAGC CTGGCTTGCA GCATGAGTTC CGACTGGGTG GAGGGCTGAA CCCTGGGCTT 
GTTCGCTCCT TGGCTGTCAG CCCCAGTGGC CGGAGTGTTG TGGCTGGCTT CTCCTCTGGC 
TTCATGGTGC TTCTAGATAC CCGCACGGGC CTGGTTCTCC GAGGCTGGCC GGCCCATGAA 
GGGGACATTC TACAGATCAA GGCTGTAGAG GGCAGTGTGA TAGTCAGCTC CTCTTCCGAC 
CATTCCTTGA CTGTTTGGAA GGAGCTGGAG CAGAAGCCCA CGCACCACTA CAAGTCAGCA 
TCGGACCCAA TCCACACCTT CGACCTGTAC GGCAGCGAGG TGGTCACTGG CACTGTGGCC 
AACAAGATTG GTGTCTGTTC CCTGCTTGAA CCACCCTCTC AGGCCACCAC AAAGCTCAGT 
TCCGAGAACT TCCGTGGTAC ACTCACCAGT CTGGCTTTGC TGCCCACGAA ACGCCACCTC 
CTGCTGGGCT CTGACAATGG CATCATCCGC CTCCTGGCAT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The BEACH-containing protein WDR81 coordinates p62 and LC3C to promote aggrephagy.
The Journal of cell biology216(5)1301-1320(2017 May)
Liu X,Li Y,Wang X,Xing R,Liu K,Gan Q,Tang C,Gao Z,Jian Y,Luo S,Guo W,Yang C

A Genetic Screen Identifies a Critical Role for the WDR81-WDR91 Complex in the Trafficking and Degradation of Tetherin.
Traffic (Copenhagen, Denmark)17(8)940-58(2016 08)
Rapiteanu R,Davis LJ,Williamson JC,Timms RT,Paul Luzio J,Lehner PJ

Negative regulation of phosphatidylinositol 3-phosphate levels in early-to-late endosome conversion.
The Journal of cell biology212(2)181-98(2016 Jan)
Liu K,Jian Y,Sun X,Yang C,Gao Z,Zhang Z,Liu X,Li Y,Xu J,Jing Y,Mitani S,He S,Yang C

WDR81 is necessary for purkinje and photoreceptor cell survival.
The Journal of neuroscience : the official journal of the Society for Neuroscience33(16)6834-44(2013 Apr)
Traka M,Millen KJ,Collins D,Elbaz B,Kidd GJ,Gomez CM,Popko B

Docking motif-guided mapping of the interactome of protein phosphatase-1.
Chemistry & biology16(4)365-71(2009 Apr)
Hendrickx A,Beullens M,Ceulemans H,Den Abt T,Van Eynde A,Nicolaescu E,Lesage B,Bollen M

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Wdr81 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

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