Irak4 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Irak4
Entrez Gene ID	300177
Full Name	interleukin-1 receptor-associated kinase 4
General protein information	Preferred Names interleukin-1 receptor-associated kinase 4 Names interleukin-1 receptor-associated kinase 4
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 7 Map Location: 7q35

mRNA and Protein(s)

mRNA	Protein	Name
XM_006242193.3	XP_006242255.1	interleukin-1 receptor-associated kinase 4 isoform X1
NM_001106791.2	NP_001100261.2	interleukin-1 receptor-associated kinase 4

Pathways from BioSystems

Homologies

Bos taurus (cattle)	IRAK4	NP_001069466.1
Gallus gallus (chicken)	IRAK4	NP_001025909.1
Arabidopsis thaliana (thale cress)	APK2A	NP_172889.1
	IRAK4	NP_001129573.1
Xenopus tropicalis (tropical clawed frog)	irak4	NP_001116877.1
Pan troglodytes (chimpanzee)	IRAK4	XP_001166075.1
Homo sapiens (human)	IRAK4	NP_001107654.1
Rattus norvegicus (Norway rat)	Irak4	NP_001100261.2
Arabidopsis thaliana (thale cress)	APK2B	NP_178383.1
Oryza sativa (rice)	Os10g0405100	NP_001064557.1
Canis lupus familiaris (dog)	IRAK4	XP_543727.1
Mus musculus (house mouse)	Irak4	NP_084202.2
Danio rerio (zebrafish)	irak4	NP_956457.1

Gene Ontology
Bibliography

Related articles in PubMed

Interleukin-1 Receptor-Associated Kinase 1/4 as a Novel Target for Inhibiting Neointimal Formation After Carotid Balloon Injury.
Bai S, Li D, Zhou Z, Cao J, Xu T, Zhang X, Wang Y, Guo J, Zhang Y
Journal of atherosclerosis and thrombosis22(12)1317-37(2015)

Effects of PMA (PHORBOL-12-MYRISTATE-13-ACETATE) on the Developing Rodent Brain.
Dzietko M, Hahnemann M, Polley O, Sifringer M, Felderhoff-Mueser U, B?hrer C
BioMed research international2015318306(2015)

Protective effect of diallyl trisulfide on liver in rats with sepsis and the mechanism.
Chen H, Zhu W, Feng J, Li S
Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban32(5)657-62(2012 Oct)

Effect of taurine on IRAK4 and NF-kappa B in Kupffer cells from rat liver grafts after ischemia-reperfusion injury.
Sun K, Chen Y, Liang SY, Liu ZJ, Liao WY, Ou ZB, Tu B, Gong JP
American journal of surgery204(3)389-95(2012 Sep)

The death domain-containing protein Unc5CL is a novel MyD88-independent activator of the pro-inflammatory IRAK signaling cascade.
Heinz LX, Rebsamen M, Rossi DC, Staehli F, Schroder K, Quadroni M, Gross O, Schneider P, Tschopp J
Cell death and differentiation19(4)722-31(2012 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

IRAK1/4 could serve as a potential therapeutic target to suppress neointimal formation in carotid arteries after balloon injury through the TLR4/NFkappaB signaling pathway
Title: Interleukin-1 Receptor-Associated Kinase 1/4 as a Novel Target for Inhibiting Neointimal Formation After Carotid Balloon Injury.

PMA treatment during a vulnerable period can alter brain development. IL-18 and IRAK-4 appear to be important for the development of PMA induced injury.
Title: Effects of PMA (PHORBOL-12-MYRISTATE-13-ACETATE) on the Developing Rodent Brain.

Data suggest that taurine could protect against hepatic ischemia/reperfusion injury after liver transplantation, and the protective effects may be through downregulation of IRAK-4 in Kupffer cells.
Title: Effect of taurine on IRAK4 and NF-kappa B in Kupffer cells from rat liver grafts after ischemia-reperfusion injury.

expression of IRAK-4 in Kupffer cells may play an important role in the formation of endotoxin tolerance
Title: Endotoxin tolerance attenuates liver ischemia/reperfusion injury by down-regulation of interleukin-1 receptor-associated kinase 4 in kupffer cells.

Data show that LXR agonists can effectively up-regulate the level of LXR gene and protein and down-regulate the levels of IRAK4 and NF-kappaB mRNA and protein expression.
Title: [Effect of the liver X receptor agonist on LPS-induced inflammatory response associated factor IRAK-4 and NF-kappaB].

The following Irak4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Irak4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa11974	NM_001106791.2 Latest version!	Rattus norvegicus interleukin-1 receptor-associated kinase 4 (Irak4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
ORa11974	XM_006242193.3 Latest version!	Rattus norvegicus interleukin-1 receptor-associated kinase 4 (Irak4), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Irak4 ( NM_001106791.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001100261.2 Rattus norvegicus interleukin-1 receptor-associated kinase 4 (Irak4), mRNA.

Price & Availability↑

CloneID	ORa11974
Clone ID Related Accession (Same CDS sequence)	XM_006242193.3 , NM_001106791.2
Accession Version	NM_001106791.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1386bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-27
Organism	Rattus norvegicus(Norway rat)
Product	interleukin-1 receptor-associated kinase 4
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AABR07058739.1 and AABR07058740.1. On Feb 18, 2009 this sequence version replaced NM_001106791.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGAGCAAGC CTTTGACACC GTCAACGTAC GTACGCAGCC TCAATGTTGG AATCCTCAGG 
AAGCTGTCGG ATTTTATTGA TCCCCAAGAA GGCTGGAAGA AACTAGCAGT AGCTATTAAA 
AAGCCATCGG GTGATGACAG ATACAATCAG TTCCATATAA GGAGATTCGA AGCCCTACTT 
CAGACTGGAA AGAGCCCCAC TTGTGAACTG CTGTTTGACT GGGGCACCAC GAACTGCACA 
GTGGGCGACC TTGTGGATCT TCTGATCCAG ATTGAGCTGT TTGCCCCTGC CACTCTCCTG 
CTGCCAGATG CTGTTCCCCA AGCCGTCCAC AGCCTACCTC CTAGAGAAGC AGCAACAGTG 
GCGCAGGCAC ACAGGCCCTG CCAGGAAAAG AACAGGACAA CCGTAACGCC TGCGCTTGCG 
CAGAAGCTAG AACCCAGCTG TGAGCTGCCC GACTCCTCCA GTCCAGGCCA TCAAAGTGTA 
GAATTTAGCG ACACTCGATT TCACAGTTTC TCATTTTATG AACTGAAGAG CATCACGAAT 
GACTTCGACG AGCGACCTGT GTCTATCGGG GGCAACCGAA TGGGAGAGGG GGGATTTGGA 
GTGGTGTACA AAGGCTGTGT GAACAACACA ACCGTAGCGG TGAAGAAGCT TGGAGCAATG 
GTGGAAATCA GTACTGAAGA ACTAAAGCAA CAGTTTGACC AAGAAATTAA AGTAATGGCC 
AAGTGTCAGC ACGAAAACCT GGTGGAGCTG CTGGGCTTCT CGAGCGACAG TGACAACCTG 
TGCTTAGTGT ATGCTTACAT GCCCAATGGT TCCTTGCTAG ACAGACTGTC CTGCCTGGAC 
GGAACGCCAC CACTTTCCTG GCACATGAGA TGCAAGATTG CTCGGGGTGC AGCAAACGGC 
ATCCGTTTTT TGCATGAAAA TCATCATATT CACAGAGATA TTAAAAGTGC AAATATCTTA 
CTAGACCAAG ACTTTACTGC CAAAATATCT GACTTTGGGC TTGCACGGGC TTCCGCGAAG 
CTTGCACAAA CGGTCATGAC CAGCCGAATT GTGGGCACAA CGGCTTATAT GGCACCTGAA 
GCTTTGCGAG GAGAAATAAC ACCCAAATCT GACATCTACA GCTTCGGTGT GGTTTTATTG 
GAGCTGATAA CCGGACTTGC GGCTGTGGAT GAAAACCGCG AACCTCAACT ACTACTGGAT 
ATTAAAGAAG AGATTGAAGA CAAGGAGAAG ACGATCGAAG ATTGCACAGA CGAGAAGATG 
AGCGATGCGG ACCCTGCGTC GGTCGAGGCG ATGTACTCTG TTGCTAGCCA GTGTCTGCAC 
GAGAAGAAAA ACAGACGGCC AGACATTGCA AAGGTTCAAC AGCTGCTACA AGAGACCTCT 
GCATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001100261.2
CDS	167..1552
Translation	MSKPLTPSTYVRSLNVGILRKLSDFIDPQEGWKKLAVAIKKPSGDDRYNQFHIRRFEALLQTGKSPTCELLFDWGTTNCTVGDLVDLLIQIELFAPATLLLPDAVPQAVHSLPPREAATVAQAHRPCQEKNRTTVTPALAQKLEPSCELPDSSSPGHQSVEFSDTRFHSFSFYELKSITNDFDERPVSIGGNRMGEGGFGVVYKGCVNNTTVAVKKLGAMVEISTEELKQQFDQEIKVMAKCQHENLVELLGFSSDSDNLCLVYAYMPNGSLLDRLSCLDGTPPLSWHMRCKIARGAANGIRFLHENHHIHRDIKSANILLDQDFTAKISDFGLARASAKLAQTVMTSRIVGTTAYMAPEALRGEITPKSDIYSFGVVLLELITGLAAVDENREPQLLLDIKEEIEDKEKTIEDCTDEKMSDADPASVEAMYSVASQCLHEKKNRRPDIAKVQQLLQETSA

Target ORF information:

RefSeq Version	NM_001106791.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus interleukin-1 receptor-associated kinase 4 (Irak4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001106791.2

ORF Insert Sequence:

ATGAGCAAGC CTTTGACACC GTCAACGTAC GTACGCAGCC TCAATGTTGG AATCCTCAGG 
AAGCTGTCGG ATTTTATTGA TCCCCAAGAA GGCTGGAAGA AACTAGCAGT AGCTATTAAA 
AAGCCATCGG GTGATGACAG ATACAATCAG TTCCATATAA GGAGATTCGA AGCCCTACTT 
CAGACTGGAA AGAGCCCCAC TTGTGAACTG CTGTTTGACT GGGGCACCAC GAACTGCACA 
GTGGGCGACC TTGTGGATCT TCTGATCCAG ATTGAGCTGT TTGCCCCTGC CACTCTCCTG 
CTGCCAGATG CTGTTCCCCA AGCCGTCCAC AGCCTACCTC CTAGAGAAGC AGCAACAGTG 
GCGCAGGCAC ACAGGCCCTG CCAGGAAAAG AACAGGACAA CCGTAACGCC TGCGCTTGCG 
CAGAAGCTAG AACCCAGCTG TGAGCTGCCC GACTCCTCCA GTCCAGGCCA TCAAAGTGTA 
GAATTTAGCG ACACTCGATT TCACAGTTTC TCATTTTATG AACTGAAGAG CATCACGAAT 
GACTTCGACG AGCGACCTGT GTCTATCGGG GGCAACCGAA TGGGAGAGGG GGGATTTGGA 
GTGGTGTACA AAGGCTGTGT GAACAACACA ACCGTAGCGG TGAAGAAGCT TGGAGCAATG 
GTGGAAATCA GTACTGAAGA ACTAAAGCAA CAGTTTGACC AAGAAATTAA AGTAATGGCC 
AAGTGTCAGC ACGAAAACCT GGTGGAGCTG CTGGGCTTCT CGAGCGACAG TGACAACCTG 
TGCTTAGTGT ATGCTTACAT GCCCAATGGT TCCTTGCTAG ACAGACTGTC CTGCCTGGAC 
GGAACGCCAC CACTTTCCTG GCACATGAGA TGCAAGATTG CTCGGGGTGC AGCAAACGGC 
ATCCGTTTTT TGCATGAAAA TCATCATATT CACAGAGATA TTAAAAGTGC AAATATCTTA 
CTAGACCAAG ACTTTACTGC CAAAATATCT GACTTTGGGC TTGCACGGGC TTCCGCGAAG 
CTTGCACAAA CGGTCATGAC CAGCCGAATT GTGGGCACAA CGGCTTATAT GGCACCTGAA 
GCTTTGCGAG GAGAAATAAC ACCCAAATCT GACATCTACA GCTTCGGTGT GGTTTTATTG 
GAGCTGATAA CCGGACTTGC GGCTGTGGAT GAAAACCGCG AACCTCAACT ACTACTGGAT 
ATTAAAGAAG AGATTGAAGA CAAGGAGAAG ACGATCGAAG ATTGCACAGA CGAGAAGATG 
AGCGATGCGG ACCCTGCGTC GGTCGAGGCG ATGTACTCTG TTGCTAGCCA GTGTCTGCAC 
GAGAAGAAAA ACAGACGGCC AGACATTGCA AAGGTTCAAC AGCTGCTACA AGAGACCTCT 
GCATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Irak4 ( XM_006242193.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006242255.1 Rattus norvegicus interleukin-1 receptor-associated kinase 4 (Irak4), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa11974
Clone ID Related Accession (Same CDS sequence)	XM_006242193.3 , NM_001106791.2
Accession Version	XM_006242193.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1386bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	interleukin-1 receptor-associated kinase 4 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005106.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006242193.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGCAAGC CTTTGACACC GTCAACGTAC GTACGCAGCC TCAATGTTGG AATCCTCAGG 
AAGCTGTCGG ATTTTATTGA TCCCCAAGAA GGCTGGAAGA AACTAGCAGT AGCTATTAAA 
AAGCCATCGG GTGATGACAG ATACAATCAG TTCCATATAA GGAGATTCGA AGCCCTACTT 
CAGACTGGAA AGAGCCCCAC TTGTGAACTG CTGTTTGACT GGGGCACCAC GAACTGCACA 
GTGGGCGACC TTGTGGATCT TCTGATCCAG ATTGAGCTGT TTGCCCCTGC CACTCTCCTG 
CTGCCAGATG CTGTTCCCCA AGCCGTCCAC AGCCTACCTC CTAGAGAAGC AGCAACAGTG 
GCGCAGGCAC ACAGGCCCTG CCAGGAAAAG AACAGGACAA CCGTAACGCC TGCGCTTGCG 
CAGAAGCTAG AACCCAGCTG TGAGCTGCCC GACTCCTCCA GTCCAGGCCA TCAAAGTGTA 
GAATTTAGCG ACACTCGATT TCACAGTTTC TCATTTTATG AACTGAAGAG CATCACGAAT 
GACTTCGACG AGCGACCTGT GTCTATCGGG GGCAACCGAA TGGGAGAGGG GGGATTTGGA 
GTGGTGTACA AAGGCTGTGT GAACAACACA ACCGTAGCGG TGAAGAAGCT TGGAGCAATG 
GTGGAAATCA GTACTGAAGA ACTAAAGCAA CAGTTTGACC AAGAAATTAA AGTAATGGCC 
AAGTGTCAGC ACGAAAACCT GGTGGAGCTG CTGGGCTTCT CGAGCGACAG TGACAACCTG 
TGCTTAGTGT ATGCTTACAT GCCCAATGGT TCCTTGCTAG ACAGACTGTC CTGCCTGGAC 
GGAACGCCAC CACTTTCCTG GCACATGAGA TGCAAGATTG CTCGGGGTGC AGCAAACGGC 
ATCCGTTTTT TGCATGAAAA TCATCATATT CACAGAGATA TTAAAAGTGC AAATATCTTA 
CTAGACCAAG ACTTTACTGC CAAAATATCT GACTTTGGGC TTGCACGGGC TTCCGCGAAG 
CTTGCACAAA CGGTCATGAC CAGCCGAATT GTGGGCACAA CGGCTTATAT GGCACCTGAA 
GCTTTGCGAG GAGAAATAAC ACCCAAATCT GACATCTACA GCTTCGGTGT GGTTTTATTG 
GAGCTGATAA CCGGACTTGC GGCTGTGGAT GAAAACCGCG AACCTCAACT ACTACTGGAT 
ATTAAAGAAG AGATTGAAGA CAAGGAGAAG ACGATCGAAG ATTGCACAGA CGAGAAGATG 
AGCGATGCGG ACCCTGCGTC GGTCGAGGCG ATGTACTCTG TTGCTAGCCA GTGTCTGCAC 
GAGAAGAAAA ACAGACGGCC AGACATTGCA AAGGTTCAAC AGCTGCTACA AGAGACCTCT 
GCATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006242255.1
CDS	91..1476
Translation	MSKPLTPSTYVRSLNVGILRKLSDFIDPQEGWKKLAVAIKKPSGDDRYNQFHIRRFEALLQTGKSPTCELLFDWGTTNCTVGDLVDLLIQIELFAPATLLLPDAVPQAVHSLPPREAATVAQAHRPCQEKNRTTVTPALAQKLEPSCELPDSSSPGHQSVEFSDTRFHSFSFYELKSITNDFDERPVSIGGNRMGEGGFGVVYKGCVNNTTVAVKKLGAMVEISTEELKQQFDQEIKVMAKCQHENLVELLGFSSDSDNLCLVYAYMPNGSLLDRLSCLDGTPPLSWHMRCKIARGAANGIRFLHENHHIHRDIKSANILLDQDFTAKISDFGLARASAKLAQTVMTSRIVGTTAYMAPEALRGEITPKSDIYSFGVVLLELITGLAAVDENREPQLLLDIKEEIEDKEKTIEDCTDEKMSDADPASVEAMYSVASQCLHEKKNRRPDIAKVQQLLQETSA

Target ORF information:

RefSeq Version	XM_006242193.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus interleukin-1 receptor-associated kinase 4 (Irak4), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006242193.3

ORF Insert Sequence:

ATGAGCAAGC CTTTGACACC GTCAACGTAC GTACGCAGCC TCAATGTTGG AATCCTCAGG 
AAGCTGTCGG ATTTTATTGA TCCCCAAGAA GGCTGGAAGA AACTAGCAGT AGCTATTAAA 
AAGCCATCGG GTGATGACAG ATACAATCAG TTCCATATAA GGAGATTCGA AGCCCTACTT 
CAGACTGGAA AGAGCCCCAC TTGTGAACTG CTGTTTGACT GGGGCACCAC GAACTGCACA 
GTGGGCGACC TTGTGGATCT TCTGATCCAG ATTGAGCTGT TTGCCCCTGC CACTCTCCTG 
CTGCCAGATG CTGTTCCCCA AGCCGTCCAC AGCCTACCTC CTAGAGAAGC AGCAACAGTG 
GCGCAGGCAC ACAGGCCCTG CCAGGAAAAG AACAGGACAA CCGTAACGCC TGCGCTTGCG 
CAGAAGCTAG AACCCAGCTG TGAGCTGCCC GACTCCTCCA GTCCAGGCCA TCAAAGTGTA 
GAATTTAGCG ACACTCGATT TCACAGTTTC TCATTTTATG AACTGAAGAG CATCACGAAT 
GACTTCGACG AGCGACCTGT GTCTATCGGG GGCAACCGAA TGGGAGAGGG GGGATTTGGA 
GTGGTGTACA AAGGCTGTGT GAACAACACA ACCGTAGCGG TGAAGAAGCT TGGAGCAATG 
GTGGAAATCA GTACTGAAGA ACTAAAGCAA CAGTTTGACC AAGAAATTAA AGTAATGGCC 
AAGTGTCAGC ACGAAAACCT GGTGGAGCTG CTGGGCTTCT CGAGCGACAG TGACAACCTG 
TGCTTAGTGT ATGCTTACAT GCCCAATGGT TCCTTGCTAG ACAGACTGTC CTGCCTGGAC 
GGAACGCCAC CACTTTCCTG GCACATGAGA TGCAAGATTG CTCGGGGTGC AGCAAACGGC 
ATCCGTTTTT TGCATGAAAA TCATCATATT CACAGAGATA TTAAAAGTGC AAATATCTTA 
CTAGACCAAG ACTTTACTGC CAAAATATCT GACTTTGGGC TTGCACGGGC TTCCGCGAAG 
CTTGCACAAA CGGTCATGAC CAGCCGAATT GTGGGCACAA CGGCTTATAT GGCACCTGAA 
GCTTTGCGAG GAGAAATAAC ACCCAAATCT GACATCTACA GCTTCGGTGT GGTTTTATTG 
GAGCTGATAA CCGGACTTGC GGCTGTGGAT GAAAACCGCG AACCTCAACT ACTACTGGAT 
ATTAAAGAAG AGATTGAAGA CAAGGAGAAG ACGATCGAAG ATTGCACAGA CGAGAAGATG 
AGCGATGCGG ACCCTGCGTC GGTCGAGGCG ATGTACTCTG TTGCTAGCCA GTGTCTGCAC 
GAGAAGAAAA ACAGACGGCC AGACATTGCA AAGGTTCAAC AGCTGCTACA AGAGACCTCT 
GCATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Interleukin-1 Receptor-Associated Kinase 1/4 as a Novel Target for Inhibiting Neointimal Formation After Carotid Balloon Injury.
Journal of atherosclerosis and thrombosis22(12)1317-37(2015)
Bai S,Li D,Zhou Z,Cao J,Xu T,Zhang X,Wang Y,Guo J,Zhang Y

Effects of PMA (PHORBOL-12-MYRISTATE-13-ACETATE) on the Developing Rodent Brain.
BioMed research international2015318306(2015)
Dzietko M,Hahnemann M,Polley O,Sifringer M,Felderhoff-Mueser U,B?hrer C

Protective effect of diallyl trisulfide on liver in rats with sepsis and the mechanism.
Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban32(5)657-62(2012 Oct)
Chen H,Zhu W,Feng J,Li S

Effect of taurine on IRAK4 and NF-kappa B in Kupffer cells from rat liver grafts after ischemia-reperfusion injury.
American journal of surgery204(3)389-95(2012 Sep)
Sun K,Chen Y,Liang SY,Liu ZJ,Liao WY,Ou ZB,Tu B,Gong JP

The death domain-containing protein Unc5CL is a novel MyD88-independent activator of the pro-inflammatory IRAK signaling cascade.
Cell death and differentiation19(4)722-31(2012 Apr)
Heinz LX,Rebsamen M,Rossi DC,Staehli F,Schroder K,Quadroni M,Gross O,Schneider P,Tschopp J

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Irak4 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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