Slc6a6 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Slc6a6
Entrez Gene ID	29464
Full Name	solute carrier family 6 member 6
General protein information	Preferred Names solute carrier family 6 member 6 Names sodium- and chloride-dependent taurine transporter Solute carrier 6 ,member 6 (taurine transporter) solute carrier family 6 (neurotransmitter transporter), member 6 solute carrier family 6 (neurotransmitter transporter, taurine), member 6 taurine/beta-alanine transporter
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 4 Map Location: 4q34
Summary	acts as a sodium and chloride dependent taurine transporter; plays a role in taurine transport; may play a role in neurotransmitter metabolism [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_008763123.2	XP_008761345.1	sodium- and chloride-dependent taurine transporter isoform X1
XM_006236903.3	XP_006236965.1	sodium- and chloride-dependent taurine transporter isoform X2
NM_017206.1	NP_058902.1	sodium- and chloride-dependent taurine transporter

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	SLC6A6	XP_001157641.2
	SLC6A6	XP_001092770.1
Gallus gallus (chicken)	SLC6A6	NP_001025771.1
Homo sapiens (human)	SLC6A6	NP_001127839.1
Canis lupus familiaris (dog)	SLC6A6	NP_001003311.1
Mus musculus (house mouse)	Slc6a6	NP_033346.2
Rattus norvegicus (Norway rat)	Slc6a6	NP_058902.1
Danio rerio (zebrafish)	slc6a6b	NP_001032750.1
Danio rerio (zebrafish)	slc6a6a	NP_001119858.1
Bos taurus (cattle)	SLC6A6	NP_777035.1
Xenopus tropicalis (tropical clawed frog)	slc6a6	XP_004914174.1

Gene Ontology
Bibliography

Related articles in PubMed

Widespread microRNA dysregulation in multiple system atrophy - disease-related alteration in miR-96.
Ubhi K, Rockenstein E, Kragh C, Inglis C, Spencer B, Michael S, Mante M, Adame A, Galasko D, Masliah E
The European journal of neuroscience39(6)1026-41(2014 Mar)

Functional impairment of rat taurine transporter by activation of nitrogen oxide through superoxide.
Koo TS, Kwon HJ, Kim MH, Kim DD, Shim CK, Chung SJ, Chong S
Drug metabolism and pharmacokinetics27(3)286-93(2012)

Roles of TauT and system A in cytoprotection of rat syncytiotrophoblast cell line exposed to hypertonic stress.
Nishimura T, Sai Y, Fujii J, Muta M, Iizasa H, Tomi M, Deureh M, Kose N, Nakashima E
Placenta31(11)1003-9(2010 Nov)

[Hyperglycemia inhibited taurine transport and taurine transporter gene expression in cultured rat cardiomyocytes].
Shi YR, Gao L, Wang SH, Pang YZ, Tang C
Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology19(2)132-6(2003 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

investigation of role of nitric oxide (NO) in regulation of functional activity of taurine transporter in renal brush border
Title: Functional impairment of rat taurine transporter by activation of nitrogen oxide through superoxide.

TauT (along with system A) plays a cytoprotective role in stressed syncytiotrophoblasts. TauT-knockdown using siRNA revealed that TauT is a major contributor to taurine uptake by TR-TBT 18d-1 cells under normal conditions.
Title: Roles of TauT and system A in cytoprotection of rat syncytiotrophoblast cell line exposed to hypertonic stress.

[(14)C]guanidinoacetate was taken up by brain parenchymal cells in a concentrative manner most likely via taurine transporter and creatine transporter
Title: The blood-brain barrier transport and cerebral distribution of guanidinoacetate in rats: involvement of creatine and taurine transporters.

SNAT2 expression is constitutively low in neurons under physiological conditions but potently induced, together with the taurine transporter TauT, in response to depletion of neutral amino acids
Title: SNAT2 amino acid transporter is regulated by amino acids of the SLC6 gamma-aminobutyric acid transporter subfamily in neocortical neurons and may play no role in delivering glutamine for glutamatergic transmission.

Glucose causes dysfunction of taurine uptake and downregulation of TAUT gene expression in cultured rat cardiomyocytes.
Title: [Hyperglycemia inhibited taurine transport and taurine transporter gene expression in cultured rat cardiomyocytes].

The following Slc6a6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Slc6a6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa03236	NM_017206.1 Latest version!	Rattus norvegicus solute carrier family 6 member 6 (Slc6a6), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
ORa03236	XM_006236903.3 Latest version!	Rattus norvegicus solute carrier family 6 member 6 (Slc6a6), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
ORa27479	XM_008763123.2 Latest version!	Rattus norvegicus solute carrier family 6 member 6 (Slc6a6), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Slc6a6 ( NM_017206.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_058902.1 Rattus norvegicus solute carrier family 6 member 6 (Slc6a6), mRNA.

Price & Availability↑

CloneID	ORa03236
Clone ID Related Accession (Same CDS sequence)	XM_006236903.3 , NM_017206.1
Accession Version	NM_017206.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1866bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-03
Organism	Rattus norvegicus(Norway rat)
Product	sodium- and chloride-dependent taurine transporter
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from M96601.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: M96601.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGGCCACCA AGGAGAAGCT TCAATGTCTG AAAGACTTCC ACAAAGACAT CCTGAAGCCT 
TCTCCAGGGA AGAGCCCAGG CACGCGGCCT GAGGATGAGG CTGATGGGAA GCCCCCTCAG 
AGGGAGAAGT GGTCCAGCAA GATCGACTTT GTGCTGTCTG TGGCCGGAGG CTTCGTGGGT 
TTGGGCAATG TCTGGCGTTT CCCGTACCTC TGCTACAAAA ATGGTGGAGG TGCATTCCTC 
ATACCGTATT TTATTTTCCT GTTTGGGAGC GGCCTGCCTG TGTTTTTCCT GGAGGTCATC 
ATAGGCCAGT ACACCTCAGA AGGGGGCATC ACCTGCTGGG AGAAGATCTG CCCCTTGTTC 
TCTGGCATTG GCTACGCGTC CATCGTCATC GTGTCCCTCC TGAATGTGTA CTACATCGTC 
ATCCTGGCCT GGGCCACATA CTACCTATTC CAGTCTTTCC AGAAGGATCT TCCCTGGGCC 
CACTGCAACC ATAGCTGGAA CACGCCACAG TGCATGGAGG ACACCCTGCG TAGGAACGAG 
AGTCACTGGG TCTCCCTTAG CGCCGCCAAC TTCACTTCGC CTGTGATCGA GTTCTGGGAG 
CGCAACGTGC TCAGCCTGTC CTCCGGAATC GACCACCCAG GCAGTCTGAA ATGGGACCTC 
GCGCTCTGCC TCCTCTTAGT CTGGCTCGTC TGTTTTTTCT GCATCTGGAA GGGTGTTCGG 
TCCACAGGCA AGGTTGTCTA CTTCACTGCT ACTTTCCCGT TTGCCATGCT TCTGGTGCTG 
CTGGTCCGTG GACTGACCCT GCCAGGTGCT GGTGAAGGCA TCAAATTCTA CCTGTACCCT 
AACATCAGCC GCCTTGAGGA CCCACAGGTG TGGATCGACG CTGGAACTCA GATATTCTTT 
TCCTACGCTA TCTGCCTGGG GGCCATGACC TCACTGGGAA GCTATAACAA GTACAAGTAT 
AACTCGTACA GGGACTGTAT GCTGCTGGGA TGCCTGAACA GTGGTACCAG TTTTGTGTCT 
GGCTTCGCAA TTTTTTCCAT CCTGGGCTTC ATGGCACAAG AGCAAGGGGT GGACATTGCT 
GATGTGGCTG AGTCAGGTCC TGGCTTGGCC TTCATTGCCT ACCCAAAAGC TGTGACCATG 
ATGCCGCTGC CCACCTTTTG GTCCATTCTG TTTTTTATTA TGCTCCTCTT GCTTGGACTG 
GACAGCCAGT TTGTTGAAGT CGAAGGACAG ATCACATCCT TGGTTGATCT TTACCCGTCC 
TTCCTAAGGA AGGGTTATCG TCGGGAAATC TTCATTGCCA TCGTGTGCAG CATCAGCTAC 
CTGCTGGGGC TGACGATGGT GACGGAGGGT GGCATGTATG TGTTTCAACT CTTTGACTAC 
TATGCAGCTA GTGGTGTATG CCTTTTGTGG GTCGCATTCT TTGAATGTTT TGTTATTGCC 
TGGATATATG GCGGTGATAA CTTATATGAC GGTATTGAGG ACATGATCGG CTATCGGCCT 
GGACCCTGGA TGAAGTACAG CTGGGCTGTC ATCACTCCAG CTCTCTGTGT TGGATGTTTC 
ATCTTCTCTC TCGTCAAGTA TGTACCCCTG ACCTACAACA AAGTCTACCG GTACCCTGAT 
TGGGCAATCG GGCTGGGCTG GGGCCTGGCC CTTTCCTCCA TGGTGTGTAT CCCCTTGGTC 
ATTGTCATCC TCCTCTGCCG GACGGAGGGA CCGCTCCGCG TGAGAATCAA ATACCTGATA 
ACCCCCAGGG AGCCCAACCG CTGGGCTGTG GAGCGTGAAG GGGCTACGCC CTTTCACTCC 
AGAGCAACCC TCATGAACGG TGCACTCATG AAACCCAGTC ACGTCATTGT GGAGACCATG 
ATGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_058902.1
CDS	127..1992
Translation	MATKEKLQCLKDFHKDILKPSPGKSPGTRPEDEADGKPPQREKWSSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIFLFGSGLPVFFLEVIIGQYTSEGGITCWEKICPLFSGIGYASIVIVSLLNVYYIVILAWATYYLFQSFQKDLPWAHCNHSWNTPQCMEDTLRRNESHWVSLSAANFTSPVIEFWERNVLSLSSGIDHPGSLKWDLALCLLLVWLVCFFCIWKGVRSTGKVVYFTATFPFAMLLVLLVRGLTLPGAGEGIKFYLYPNISRLEDPQVWIDAGTQIFFSYAICLGAMTSLGSYNKYKYNSYRDCMLLGCLNSGTSFVSGFAIFSILGFMAQEQGVDIADVAESGPGLAFIAYPKAVTMMPLPTFWSILFFIMLLLLGLDSQFVEVEGQITSLVDLYPSFLRKGYRREIFIAIVCSISYLLGLTMVTEGGMYVFQLFDYYAASGVCLLWVAFFECFVIAWIYGGDNLYDGIEDMIGYRPGPWMKYSWAVITPALCVGCFIFSLVKYVPLTYNKVYRYPDWAIGLGWGLALSSMVCIPLVIVILLCRTEGPLRVRIKYLITPREPNRWAVEREGATPFHSRATLMNGALMKPSHVIVETMM

Target ORF information:

RefSeq Version	NM_017206.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus solute carrier family 6 member 6 (Slc6a6), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_017206.1

ORF Insert Sequence:

ATGGCCACCA AGGAGAAGCT TCAATGTCTG AAAGACTTCC ACAAAGACAT CCTGAAGCCT 
TCTCCAGGGA AGAGCCCAGG CACGCGGCCT GAGGATGAGG CTGATGGGAA GCCCCCTCAG 
AGGGAGAAGT GGTCCAGCAA GATCGACTTT GTGCTGTCTG TGGCCGGAGG CTTCGTGGGT 
TTGGGCAATG TCTGGCGTTT CCCGTACCTC TGCTACAAAA ATGGTGGAGG TGCATTCCTC 
ATACCGTATT TTATTTTCCT GTTTGGGAGC GGCCTGCCTG TGTTTTTCCT GGAGGTCATC 
ATAGGCCAGT ACACCTCAGA AGGGGGCATC ACCTGCTGGG AGAAGATCTG CCCCTTGTTC 
TCTGGCATTG GCTACGCGTC CATCGTCATC GTGTCCCTCC TGAATGTGTA CTACATCGTC 
ATCCTGGCCT GGGCCACATA CTACCTATTC CAGTCTTTCC AGAAGGATCT TCCCTGGGCC 
CACTGCAACC ATAGCTGGAA CACGCCACAG TGCATGGAGG ACACCCTGCG TAGGAACGAG 
AGTCACTGGG TCTCCCTTAG CGCCGCCAAC TTCACTTCGC CTGTGATCGA GTTCTGGGAG 
CGCAACGTGC TCAGCCTGTC CTCCGGAATC GACCACCCAG GCAGTCTGAA ATGGGACCTC 
GCGCTCTGCC TCCTCTTAGT CTGGCTCGTC TGTTTTTTCT GCATCTGGAA GGGTGTTCGG 
TCCACAGGCA AGGTTGTCTA CTTCACTGCT ACTTTCCCGT TTGCCATGCT TCTGGTGCTG 
CTGGTCCGTG GACTGACCCT GCCAGGTGCT GGTGAAGGCA TCAAATTCTA CCTGTACCCT 
AACATCAGCC GCCTTGAGGA CCCACAGGTG TGGATCGACG CTGGAACTCA GATATTCTTT 
TCCTACGCTA TCTGCCTGGG GGCCATGACC TCACTGGGAA GCTATAACAA GTACAAGTAT 
AACTCGTACA GGGACTGTAT GCTGCTGGGA TGCCTGAACA GTGGTACCAG TTTTGTGTCT 
GGCTTCGCAA TTTTTTCCAT CCTGGGCTTC ATGGCACAAG AGCAAGGGGT GGACATTGCT 
GATGTGGCTG AGTCAGGTCC TGGCTTGGCC TTCATTGCCT ACCCAAAAGC TGTGACCATG 
ATGCCGCTGC CCACCTTTTG GTCCATTCTG TTTTTTATTA TGCTCCTCTT GCTTGGACTG 
GACAGCCAGT TTGTTGAAGT CGAAGGACAG ATCACATCCT TGGTTGATCT TTACCCGTCC 
TTCCTAAGGA AGGGTTATCG TCGGGAAATC TTCATTGCCA TCGTGTGCAG CATCAGCTAC 
CTGCTGGGGC TGACGATGGT GACGGAGGGT GGCATGTATG TGTTTCAACT CTTTGACTAC 
TATGCAGCTA GTGGTGTATG CCTTTTGTGG GTCGCATTCT TTGAATGTTT TGTTATTGCC 
TGGATATATG GCGGTGATAA CTTATATGAC GGTATTGAGG ACATGATCGG CTATCGGCCT 
GGACCCTGGA TGAAGTACAG CTGGGCTGTC ATCACTCCAG CTCTCTGTGT TGGATGTTTC 
ATCTTCTCTC TCGTCAAGTA TGTACCCCTG ACCTACAACA AAGTCTACCG GTACCCTGAT 
TGGGCAATCG GGCTGGGCTG GGGCCTGGCC CTTTCCTCCA TGGTGTGTAT CCCCTTGGTC 
ATTGTCATCC TCCTCTGCCG GACGGAGGGA CCGCTCCGCG TGAGAATCAA ATACCTGATA 
ACCCCCAGGG AGCCCAACCG CTGGGCTGTG GAGCGTGAAG GGGCTACGCC CTTTCACTCC 
AGAGCAACCC TCATGAACGG TGCACTCATG AAACCCAGTC ACGTCATTGT GGAGACCATG 
ATGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Slc6a6 ( XM_006236903.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006236965.1 Rattus norvegicus solute carrier family 6 member 6 (Slc6a6), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa03236
Clone ID Related Accession (Same CDS sequence)	XM_006236903.3 , NM_017206.1
Accession Version	XM_006236903.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1866bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	sodium- and chloride-dependent taurine transporter isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005103.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006236903.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCCACCA AGGAGAAGCT TCAATGTCTG AAAGACTTCC ACAAAGACAT CCTGAAGCCT 
TCTCCAGGGA AGAGCCCAGG CACGCGGCCT GAGGATGAGG CTGATGGGAA GCCCCCTCAG 
AGGGAGAAGT GGTCCAGCAA GATCGACTTT GTGCTGTCTG TGGCCGGAGG CTTCGTGGGT 
TTGGGCAATG TCTGGCGTTT CCCGTACCTC TGCTACAAAA ATGGTGGAGG TGCATTCCTC 
ATACCGTATT TTATTTTCCT GTTTGGGAGC GGCCTGCCTG TGTTTTTCCT GGAGGTCATC 
ATAGGCCAGT ACACCTCAGA AGGGGGCATC ACCTGCTGGG AGAAGATCTG CCCCTTGTTC 
TCTGGCATTG GCTACGCGTC CATCGTCATC GTGTCCCTCC TGAATGTGTA CTACATCGTC 
ATCCTGGCCT GGGCCACATA CTACCTATTC CAGTCTTTCC AGAAGGATCT TCCCTGGGCC 
CACTGCAACC ATAGCTGGAA CACGCCACAG TGCATGGAGG ACACCCTGCG TAGGAACGAG 
AGTCACTGGG TCTCCCTTAG CGCCGCCAAC TTCACTTCGC CTGTGATCGA GTTCTGGGAG 
CGCAACGTGC TCAGCCTGTC CTCCGGAATC GACCACCCAG GCAGTCTGAA ATGGGACCTC 
GCGCTCTGCC TCCTCTTAGT CTGGCTCGTC TGTTTTTTCT GCATCTGGAA GGGTGTTCGG 
TCCACAGGCA AGGTTGTCTA CTTCACTGCT ACTTTCCCGT TTGCCATGCT TCTGGTGCTG 
CTGGTCCGTG GACTGACCCT GCCAGGTGCT GGTGAAGGCA TCAAATTCTA CCTGTACCCT 
AACATCAGCC GCCTTGAGGA CCCACAGGTG TGGATCGACG CTGGAACTCA GATATTCTTT 
TCCTACGCTA TCTGCCTGGG GGCCATGACC TCACTGGGAA GCTATAACAA GTACAAGTAT 
AACTCGTACA GGGACTGTAT GCTGCTGGGA TGCCTGAACA GTGGTACCAG TTTTGTGTCT 
GGCTTCGCAA TTTTTTCCAT CCTGGGCTTC ATGGCACAAG AGCAAGGGGT GGACATTGCT 
GATGTGGCTG AGTCAGGTCC TGGCTTGGCC TTCATTGCCT ACCCAAAAGC TGTGACCATG 
ATGCCGCTGC CCACCTTTTG GTCCATTCTG TTTTTTATTA TGCTCCTCTT GCTTGGACTG 
GACAGCCAGT TTGTTGAAGT CGAAGGACAG ATCACATCCT TGGTTGATCT TTACCCGTCC 
TTCCTAAGGA AGGGTTATCG TCGGGAAATC TTCATTGCCA TCGTGTGCAG CATCAGCTAC 
CTGCTGGGGC TGACGATGGT GACGGAGGGT GGCATGTATG TGTTTCAACT CTTTGACTAC 
TATGCAGCTA GTGGTGTATG CCTTTTGTGG GTCGCATTCT TTGAATGTTT TGTTATTGCC 
TGGATATATG GCGGTGATAA CTTATATGAC GGTATTGAGG ACATGATCGG CTATCGGCCT 
GGACCCTGGA TGAAGTACAG CTGGGCTGTC ATCACTCCAG CTCTCTGTGT TGGATGTTTC 
ATCTTCTCTC TCGTCAAGTA TGTACCCCTG ACCTACAACA AAGTCTACCG GTACCCTGAT 
TGGGCAATCG GGCTGGGCTG GGGCCTGGCC CTTTCCTCCA TGGTGTGTAT CCCCTTGGTC 
ATTGTCATCC TCCTCTGCCG GACGGAGGGA CCGCTCCGCG TGAGAATCAA ATACCTGATA 
ACCCCCAGGG AGCCCAACCG CTGGGCTGTG GAGCGTGAAG GGGCTACGCC CTTTCACTCC 
AGAGCAACCC TCATGAACGG TGCACTCATG AAACCCAGTC ACGTCATTGT GGAGACCATG 
ATGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006236965.1
CDS	233..2098
Translation	MATKEKLQCLKDFHKDILKPSPGKSPGTRPEDEADGKPPQREKWSSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIFLFGSGLPVFFLEVIIGQYTSEGGITCWEKICPLFSGIGYASIVIVSLLNVYYIVILAWATYYLFQSFQKDLPWAHCNHSWNTPQCMEDTLRRNESHWVSLSAANFTSPVIEFWERNVLSLSSGIDHPGSLKWDLALCLLLVWLVCFFCIWKGVRSTGKVVYFTATFPFAMLLVLLVRGLTLPGAGEGIKFYLYPNISRLEDPQVWIDAGTQIFFSYAICLGAMTSLGSYNKYKYNSYRDCMLLGCLNSGTSFVSGFAIFSILGFMAQEQGVDIADVAESGPGLAFIAYPKAVTMMPLPTFWSILFFIMLLLLGLDSQFVEVEGQITSLVDLYPSFLRKGYRREIFIAIVCSISYLLGLTMVTEGGMYVFQLFDYYAASGVCLLWVAFFECFVIAWIYGGDNLYDGIEDMIGYRPGPWMKYSWAVITPALCVGCFIFSLVKYVPLTYNKVYRYPDWAIGLGWGLALSSMVCIPLVIVILLCRTEGPLRVRIKYLITPREPNRWAVEREGATPFHSRATLMNGALMKPSHVIVETMM

Target ORF information:

RefSeq Version	XM_006236903.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus solute carrier family 6 member 6 (Slc6a6), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006236903.3

ORF Insert Sequence:

ATGGCCACCA AGGAGAAGCT TCAATGTCTG AAAGACTTCC ACAAAGACAT CCTGAAGCCT 
TCTCCAGGGA AGAGCCCAGG CACGCGGCCT GAGGATGAGG CTGATGGGAA GCCCCCTCAG 
AGGGAGAAGT GGTCCAGCAA GATCGACTTT GTGCTGTCTG TGGCCGGAGG CTTCGTGGGT 
TTGGGCAATG TCTGGCGTTT CCCGTACCTC TGCTACAAAA ATGGTGGAGG TGCATTCCTC 
ATACCGTATT TTATTTTCCT GTTTGGGAGC GGCCTGCCTG TGTTTTTCCT GGAGGTCATC 
ATAGGCCAGT ACACCTCAGA AGGGGGCATC ACCTGCTGGG AGAAGATCTG CCCCTTGTTC 
TCTGGCATTG GCTACGCGTC CATCGTCATC GTGTCCCTCC TGAATGTGTA CTACATCGTC 
ATCCTGGCCT GGGCCACATA CTACCTATTC CAGTCTTTCC AGAAGGATCT TCCCTGGGCC 
CACTGCAACC ATAGCTGGAA CACGCCACAG TGCATGGAGG ACACCCTGCG TAGGAACGAG 
AGTCACTGGG TCTCCCTTAG CGCCGCCAAC TTCACTTCGC CTGTGATCGA GTTCTGGGAG 
CGCAACGTGC TCAGCCTGTC CTCCGGAATC GACCACCCAG GCAGTCTGAA ATGGGACCTC 
GCGCTCTGCC TCCTCTTAGT CTGGCTCGTC TGTTTTTTCT GCATCTGGAA GGGTGTTCGG 
TCCACAGGCA AGGTTGTCTA CTTCACTGCT ACTTTCCCGT TTGCCATGCT TCTGGTGCTG 
CTGGTCCGTG GACTGACCCT GCCAGGTGCT GGTGAAGGCA TCAAATTCTA CCTGTACCCT 
AACATCAGCC GCCTTGAGGA CCCACAGGTG TGGATCGACG CTGGAACTCA GATATTCTTT 
TCCTACGCTA TCTGCCTGGG GGCCATGACC TCACTGGGAA GCTATAACAA GTACAAGTAT 
AACTCGTACA GGGACTGTAT GCTGCTGGGA TGCCTGAACA GTGGTACCAG TTTTGTGTCT 
GGCTTCGCAA TTTTTTCCAT CCTGGGCTTC ATGGCACAAG AGCAAGGGGT GGACATTGCT 
GATGTGGCTG AGTCAGGTCC TGGCTTGGCC TTCATTGCCT ACCCAAAAGC TGTGACCATG 
ATGCCGCTGC CCACCTTTTG GTCCATTCTG TTTTTTATTA TGCTCCTCTT GCTTGGACTG 
GACAGCCAGT TTGTTGAAGT CGAAGGACAG ATCACATCCT TGGTTGATCT TTACCCGTCC 
TTCCTAAGGA AGGGTTATCG TCGGGAAATC TTCATTGCCA TCGTGTGCAG CATCAGCTAC 
CTGCTGGGGC TGACGATGGT GACGGAGGGT GGCATGTATG TGTTTCAACT CTTTGACTAC 
TATGCAGCTA GTGGTGTATG CCTTTTGTGG GTCGCATTCT TTGAATGTTT TGTTATTGCC 
TGGATATATG GCGGTGATAA CTTATATGAC GGTATTGAGG ACATGATCGG CTATCGGCCT 
GGACCCTGGA TGAAGTACAG CTGGGCTGTC ATCACTCCAG CTCTCTGTGT TGGATGTTTC 
ATCTTCTCTC TCGTCAAGTA TGTACCCCTG ACCTACAACA AAGTCTACCG GTACCCTGAT 
TGGGCAATCG GGCTGGGCTG GGGCCTGGCC CTTTCCTCCA TGGTGTGTAT CCCCTTGGTC 
ATTGTCATCC TCCTCTGCCG GACGGAGGGA CCGCTCCGCG TGAGAATCAA ATACCTGATA 
ACCCCCAGGG AGCCCAACCG CTGGGCTGTG GAGCGTGAAG GGGCTACGCC CTTTCACTCC 
AGAGCAACCC TCATGAACGG TGCACTCATG AAACCCAGTC ACGTCATTGT GGAGACCATG 
ATGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Slc6a6 ( XM_008763123.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008761345.1 Rattus norvegicus solute carrier family 6 member 6 (Slc6a6), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa27479
Clone ID Related Accession (Same CDS sequence)	XM_008763123.2
Accession Version	XM_008763123.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1896bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	sodium- and chloride-dependent taurine transporter isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005103.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008763123.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACTCCCG TGCACCCAGA AAACGAGGAG ATGGCCACCA AGGAGAAGCT TCAATGTCTG 
AAAGACTTCC ACAAAGACAT CCTGAAGCCT TCTCCAGGGA AGAGCCCAGG CACGCGGCCT 
GAGGATGAGG CTGATGGGAA GCCCCCTCAG AGGGAGAAGT GGTCCAGCAA GATCGACTTT 
GTGCTGTCTG TGGCCGGAGG CTTCGTGGGT TTGGGCAATG TCTGGCGTTT CCCGTACCTC 
TGCTACAAAA ATGGTGGAGG TGCATTCCTC ATACCGTATT TTATTTTCCT GTTTGGGAGC 
GGCCTGCCTG TGTTTTTCCT GGAGGTCATC ATAGGCCAGT ACACCTCAGA AGGGGGCATC 
ACCTGCTGGG AGAAGATCTG CCCCTTGTTC TCTGGCATTG GCTACGCGTC CATCGTCATC 
GTGTCCCTCC TGAATGTGTA CTACATCGTC ATCCTGGCCT GGGCCACATA CTACCTATTC 
CAGTCTTTCC AGAAGGATCT TCCCTGGGCC CACTGCAACC ATAGCTGGAA CACGCCACAG 
TGCATGGAGG ACACCCTGCG TAGGAACGAG AGTCACTGGG TCTCCCTTAG CGCCGCCAAC 
TTCACTTCGC CTGTGATCGA GTTCTGGGAG CGCAACGTGC TCAGCCTGTC CTCCGGAATC 
GACCACCCAG GCAGTCTGAA ATGGGACCTC GCGCTCTGCC TCCTCTTAGT CTGGCTCGTC 
TGTTTTTTCT GCATCTGGAA GGGTGTTCGG TCCACAGGCA AGGTTGTCTA CTTCACTGCT 
ACTTTCCCGT TTGCCATGCT TCTGGTGCTG CTGGTCCGTG GACTGACCCT GCCAGGTGCT 
GGTGAAGGCA TCAAATTCTA CCTGTACCCT AACATCAGCC GCCTTGAGGA CCCACAGGTG 
TGGATCGACG CTGGAACTCA GATATTCTTT TCCTACGCTA TCTGCCTGGG GGCCATGACC 
TCACTGGGAA GCTATAACAA GTACAAGTAT AACTCGTACA GGGACTGTAT GCTGCTGGGA 
TGCCTGAACA GTGGTACCAG TTTTGTGTCT GGCTTCGCAA TTTTTTCCAT CCTGGGCTTC 
ATGGCACAAG AGCAAGGGGT GGACATTGCT GATGTGGCTG AGTCAGGTCC TGGCTTGGCC 
TTCATTGCCT ACCCAAAAGC TGTGACCATG ATGCCGCTGC CCACCTTTTG GTCCATTCTG 
TTTTTTATTA TGCTCCTCTT GCTTGGACTG GACAGCCAGT TTGTTGAAGT CGAAGGACAG 
ATCACATCCT TGGTTGATCT TTACCCGTCC TTCCTAAGGA AGGGTTATCG TCGGGAAATC 
TTCATTGCCA TCGTGTGCAG CATCAGCTAC CTGCTGGGGC TGACGATGGT GACGGAGGGT 
GGCATGTATG TGTTTCAACT CTTTGACTAC TATGCAGCTA GTGGTGTATG CCTTTTGTGG 
GTCGCATTCT TTGAATGTTT TGTTATTGCC TGGATATATG GCGGTGATAA CTTATATGAC 
GGTATTGAGG ACATGATCGG CTATCGGCCT GGACCCTGGA TGAAGTACAG CTGGGCTGTC 
ATCACTCCAG CTCTCTGTGT TGGATGTTTC ATCTTCTCTC TCGTCAAGTA TGTACCCCTG 
ACCTACAACA AAGTCTACCG GTACCCTGAT TGGGCAATCG GGCTGGGCTG GGGCCTGGCC 
CTTTCCTCCA TGGTGTGTAT CCCCTTGGTC ATTGTCATCC TCCTCTGCCG GACGGAGGGA 
CCGCTCCGCG TGAGAATCAA ATACCTGATA ACCCCCAGGG AGCCCAACCG CTGGGCTGTG 
GAGCGTGAAG GGGCTACGCC CTTTCACTCC AGAGCAACCC TCATGAACGG TGCACTCATG 
AAACCCAGTC ACGTCATTGT GGAGACCATG ATGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008761345.1
CDS	364..2259
Translation	MTPVHPENEEMATKEKLQCLKDFHKDILKPSPGKSPGTRPEDEADGKPPQREKWSSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIFLFGSGLPVFFLEVIIGQYTSEGGITCWEKICPLFSGIGYASIVIVSLLNVYYIVILAWATYYLFQSFQKDLPWAHCNHSWNTPQCMEDTLRRNESHWVSLSAANFTSPVIEFWERNVLSLSSGIDHPGSLKWDLALCLLLVWLVCFFCIWKGVRSTGKVVYFTATFPFAMLLVLLVRGLTLPGAGEGIKFYLYPNISRLEDPQVWIDAGTQIFFSYAICLGAMTSLGSYNKYKYNSYRDCMLLGCLNSGTSFVSGFAIFSILGFMAQEQGVDIADVAESGPGLAFIAYPKAVTMMPLPTFWSILFFIMLLLLGLDSQFVEVEGQITSLVDLYPSFLRKGYRREIFIAIVCSISYLLGLTMVTEGGMYVFQLFDYYAASGVCLLWVAFFECFVIAWIYGGDNLYDGIEDMIGYRPGPWMKYSWAVITPALCVGCFIFSLVKYVPLTYNKVYRYPDWAIGLGWGLALSSMVCIPLVIVILLCRTEGPLRVRIKYLITPREPNRWAVEREGATPFHSRATLMNGALMKPSHVIVETMM

Target ORF information:

RefSeq Version	XM_008763123.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus solute carrier family 6 member 6 (Slc6a6), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008763123.2

ORF Insert Sequence:

ATGACTCCCG TGCACCCAGA AAACGAGGAG ATGGCCACCA AGGAGAAGCT TCAATGTCTG 
AAAGACTTCC ACAAAGACAT CCTGAAGCCT TCTCCAGGGA AGAGCCCAGG CACGCGGCCT 
GAGGATGAGG CTGATGGGAA GCCCCCTCAG AGGGAGAAGT GGTCCAGCAA GATCGACTTT 
GTGCTGTCTG TGGCCGGAGG CTTCGTGGGT TTGGGCAATG TCTGGCGTTT CCCGTACCTC 
TGCTACAAAA ATGGTGGAGG TGCATTCCTC ATACCGTATT TTATTTTCCT GTTTGGGAGC 
GGCCTGCCTG TGTTTTTCCT GGAGGTCATC ATAGGCCAGT ACACCTCAGA AGGGGGCATC 
ACCTGCTGGG AGAAGATCTG CCCCTTGTTC TCTGGCATTG GCTACGCGTC CATCGTCATC 
GTGTCCCTCC TGAATGTGTA CTACATCGTC ATCCTGGCCT GGGCCACATA CTACCTATTC 
CAGTCTTTCC AGAAGGATCT TCCCTGGGCC CACTGCAACC ATAGCTGGAA CACGCCACAG 
TGCATGGAGG ACACCCTGCG TAGGAACGAG AGTCACTGGG TCTCCCTTAG CGCCGCCAAC 
TTCACTTCGC CTGTGATCGA GTTCTGGGAG CGCAACGTGC TCAGCCTGTC CTCCGGAATC 
GACCACCCAG GCAGTCTGAA ATGGGACCTC GCGCTCTGCC TCCTCTTAGT CTGGCTCGTC 
TGTTTTTTCT GCATCTGGAA GGGTGTTCGG TCCACAGGCA AGGTTGTCTA CTTCACTGCT 
ACTTTCCCGT TTGCCATGCT TCTGGTGCTG CTGGTCCGTG GACTGACCCT GCCAGGTGCT 
GGTGAAGGCA TCAAATTCTA CCTGTACCCT AACATCAGCC GCCTTGAGGA CCCACAGGTG 
TGGATCGACG CTGGAACTCA GATATTCTTT TCCTACGCTA TCTGCCTGGG GGCCATGACC 
TCACTGGGAA GCTATAACAA GTACAAGTAT AACTCGTACA GGGACTGTAT GCTGCTGGGA 
TGCCTGAACA GTGGTACCAG TTTTGTGTCT GGCTTCGCAA TTTTTTCCAT CCTGGGCTTC 
ATGGCACAAG AGCAAGGGGT GGACATTGCT GATGTGGCTG AGTCAGGTCC TGGCTTGGCC 
TTCATTGCCT ACCCAAAAGC TGTGACCATG ATGCCGCTGC CCACCTTTTG GTCCATTCTG 
TTTTTTATTA TGCTCCTCTT GCTTGGACTG GACAGCCAGT TTGTTGAAGT CGAAGGACAG 
ATCACATCCT TGGTTGATCT TTACCCGTCC TTCCTAAGGA AGGGTTATCG TCGGGAAATC 
TTCATTGCCA TCGTGTGCAG CATCAGCTAC CTGCTGGGGC TGACGATGGT GACGGAGGGT 
GGCATGTATG TGTTTCAACT CTTTGACTAC TATGCAGCTA GTGGTGTATG CCTTTTGTGG 
GTCGCATTCT TTGAATGTTT TGTTATTGCC TGGATATATG GCGGTGATAA CTTATATGAC 
GGTATTGAGG ACATGATCGG CTATCGGCCT GGACCCTGGA TGAAGTACAG CTGGGCTGTC 
ATCACTCCAG CTCTCTGTGT TGGATGTTTC ATCTTCTCTC TCGTCAAGTA TGTACCCCTG 
ACCTACAACA AAGTCTACCG GTACCCTGAT TGGGCAATCG GGCTGGGCTG GGGCCTGGCC 
CTTTCCTCCA TGGTGTGTAT CCCCTTGGTC ATTGTCATCC TCCTCTGCCG GACGGAGGGA 
CCGCTCCGCG TGAGAATCAA ATACCTGATA ACCCCCAGGG AGCCCAACCG CTGGGCTGTG 
GAGCGTGAAG GGGCTACGCC CTTTCACTCC AGAGCAACCC TCATGAACGG TGCACTCATG 
AAACCCAGTC ACGTCATTGT GGAGACCATG ATGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Widespread microRNA dysregulation in multiple system atrophy - disease-related alteration in miR-96.
The European journal of neuroscience39(6)1026-41(2014 Mar)
Ubhi K,Rockenstein E,Kragh C,Inglis C,Spencer B,Michael S,Mante M,Adame A,Galasko D,Masliah E

Functional impairment of rat taurine transporter by activation of nitrogen oxide through superoxide.
Drug metabolism and pharmacokinetics27(3)286-93(2012)
Koo TS,Kwon HJ,Kim MH,Kim DD,Shim CK,Chung SJ,Chong S

Roles of TauT and system A in cytoprotection of rat syncytiotrophoblast cell line exposed to hypertonic stress.
Placenta31(11)1003-9(2010 Nov)
Nishimura T,Sai Y,Fujii J,Muta M,Iizasa H,Tomi M,Deureh M,Kose N,Nakashima E

[Hyperglycemia inhibited taurine transport and taurine transporter gene expression in cultured rat cardiomyocytes].
Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology19(2)132-6(2003 May)
Shi YR,Gao L,Wang SH,Pang YZ,Tang C

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Slc6a6 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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