Pbk cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Pbk
Entrez Gene ID	290326
Full Name	PDZ binding kinase
General protein information	Preferred Names PDZ binding kinase Names lymphokine-activated killer T-cell-originated protein kinase
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 15 Map Location: 15p12

mRNA and Protein(s)

mRNA	Protein	Name
XM_006252105.2	XP_006252167.1	lymphokine-activated killer T-cell-originated protein kinase isoform X1
NM_001079937.1	NP_001073406.1	lymphokine-activated killer T-cell-originated protein kinase
XM_006252106.3	XP_006252168.1	lymphokine-activated killer T-cell-originated protein kinase isoform X1
XM_006252104.3	XP_006252166.1	lymphokine-activated killer T-cell-originated protein kinase isoform X1
XM_006252103.3	XP_006252165.1	lymphokine-activated killer T-cell-originated protein kinase isoform X1

Pathways from BioSystems

Homologies

Drosophila melanogaster (fruit fly)	CG8173	NP_573239.1
Homo sapiens (human)	PBK	NP_060962.2
Canis lupus familiaris (dog)	PBK	XP_534564.1
Danio rerio (zebrafish)	pbk	NP_001002387.1
	PBK	XP_001109768.1
Xenopus tropicalis (tropical clawed frog)	pbk	NP_001011346.1
Bos taurus (cattle)	PBK	NP_001095648.1
Rattus norvegicus (Norway rat)	Pbk	NP_001073406.1
Pan troglodytes (chimpanzee)	PBK	NP_001233441.1
Mus musculus (house mouse)	Pbk	NP_075698.1
Gallus gallus (chicken)	PBK	NP_001264928.1

Gene Ontology
Bibliography

Related articles in PubMed

Identification of the oncogenic kinase TOPK/PBK as a master mitotic regulator of C2H2 zinc finger proteins.
Rizkallah R, Batsomboon P, Dudley GB, Hurt MM
Oncotarget6(3)1446-61(2015 Jan)

Activation of T-LAK-cell-originated protein kinase-mediated antioxidation protects against focal cerebral ischemia-reperfusion injury.
Zhao H, Wang R, Tao Z, Yan F, Gao L, Liu X, Wang N, Min L, Jia Y, Zhao Y, Ji X, Luo Y
The FEBS journal281(19)4411-20(2014 Oct)

T-LAK cell-originated protein kinase (TOPK) phosphorylation of MKP1 protein prevents solar ultraviolet light-induced inflammation through inhibition of the p38 protein signaling pathway.
Li S, Zhu F, Zykova T, Kim MO, Cho YY, Bode AM, Peng C, Ma W, Carper A, Langfald A, Dong Z
The Journal of biological chemistry286(34)29601-9(2011 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

TOPK confers neuroprotection against focal cerebral ischemia-reperfusion injury by antioxidative function.
Title: Activation of T-LAK-cell-originated protein kinase-mediated antioxidation protects against focal cerebral ischemia-reperfusion injury.

The following Pbk gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Pbk cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa10604	NM_001079937.1 Latest version!	Rattus norvegicus PDZ binding kinase (Pbk), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
ORa10604	XM_006252103.3 Latest version!	Rattus norvegicus PDZ binding kinase (Pbk), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
ORa10604	XM_006252105.2 Latest version!	Rattus norvegicus PDZ binding kinase (Pbk), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
ORa10604	XM_006252106.3 Latest version!	Rattus norvegicus PDZ binding kinase (Pbk), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
ORa10604	XM_006252104.3 Latest version!	Rattus norvegicus PDZ binding kinase (Pbk), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Pbk ( NM_001079937.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001073406.1 Rattus norvegicus PDZ binding kinase (Pbk), mRNA.

Price & Availability↑

CloneID	ORa10604
Clone ID Related Accession (Same CDS sequence)	XM_006252105.2 , NM_001079937.1 , XM_006252106.3 , XM_006252104.3 , XM_006252103.3
Accession Version	NM_001079937.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1014bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Rattus norvegicus(Norway rat)
Product	lymphokine-activated killer T-cell-originated protein kinase
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC129099.1. On or before Jan 11, 2007 this sequence version replaced XM_224300.4, XM_001066776.1. ##Evidence-Data-START## Transcript exon combination :: BC129099.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2689599, SAMEA2689604 [ECO:0000348] ##Evidence-Data-END##

ATGGAAGGAA TCAGTAATTT CAAGACGCCA AACAAATTAT CTGAAAAAAG GAAATCTGTA 
TTATGTTCAA CTCCATGTGT AAATATCCCT GCCTCTCCAT TTATGCAGAA GCTCGGCTTT 
GGGACTGGGG TCAGTGTTTA CCTAATGAAA AGATCTCCGA GAGGGTTGTC CCATTCTCCT 
TGGGCTGTGA AAAAGATAAA TCCTTTATGC GATGATCATT ATCGAACTGT GTATCAGAAG 
AGACTAACTG ATGAAGCTAA GATTTTAAAA AACCTTAATC ACCCAAACAT TGTAGGCTAT 
CGTGCTTTTA CTGAAGCCAG TGATGGTAGT CTGTGCCTTG CTATGGAGTA TGGAGGTGAA 
AAGTCTCTGA ATGACTTAAT AGAAGAGCGG AACAAAGACA GTGGAAGTCC TTTTCCAGCA 
GCTGTAATTC TCAGAGTTGC TTTGCACATG GCAAGAGGGC TAAAGTATCT GCATCAGGAA 
AAGAAGCTGC TGCATGGAGA CATAAAGTCT TCAAATGTTG TAATTAAAGG TGACTTTGAA 
ACAATTAAAA TCTGTGATGT AGGAGTCTCT CTGCCATTGG ATGAAAATAT GACTGTGACT 
GATCCTGAGG CCTGTTATAT TGGTACTGAG CCATGGAAAC CCAAAGAAGC ATTGGAGGAA 
AATGGCATTA TTACTGACAA GGCAGATATG TTTGCTTTTG GCCTTACTCT TTGGGAAATG 
ATGACTTTAT GTATTCCACA CATCAACCTT CCAGATGATG ATGATGATGA AGATGCAACA 
TTTGATGAGA GTGACTTCGA TGATGAAGCT TACTATGCAG CTCTGGGGAC AAGACCATCC 
ATCAATATGG AAGAACTGGA TGAATCCTAC CAGAAGGTCA TTGAACTCTT CTGTGTGTGT 
ACTAATGAGG ATCCTAAAGA TCGCCCATCT GCTGCACACA TCGTTGAAGC TTTGGAACTA 
GATGGCCAAT GTTGTGGTCT AAGCTCGAAG CATAGCTTGT ATGGGAACTG TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001073406.1
CDS	250..1263
Translation	MEGISNFKTPNKLSEKRKSVLCSTPCVNIPASPFMQKLGFGTGVSVYLMKRSPRGLSHSPWAVKKINPLCDDHYRTVYQKRLTDEAKILKNLNHPNIVGYRAFTEASDGSLCLAMEYGGEKSLNDLIEERNKDSGSPFPAAVILRVALHMARGLKYLHQEKKLLHGDIKSSNVVIKGDFETIKICDVGVSLPLDENMTVTDPEACYIGTEPWKPKEALEENGIITDKADMFAFGLTLWEMMTLCIPHINLPDDDDDEDATFDESDFDDEAYYAALGTRPSINMEELDESYQKVIELFCVCTNEDPKDRPSAAHIVEALELDGQCCGLSSKHSLYGNC

Target ORF information:

RefSeq Version	NM_001079937.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus PDZ binding kinase (Pbk), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001079937.1

ORF Insert Sequence:

ATGGAAGGAA TCAGTAATTT CAAGACGCCA AACAAATTAT CTGAAAAAAG GAAATCTGTA 
TTATGTTCAA CTCCATGTGT AAATATCCCT GCCTCTCCAT TTATGCAGAA GCTCGGCTTT 
GGGACTGGGG TCAGTGTTTA CCTAATGAAA AGATCTCCGA GAGGGTTGTC CCATTCTCCT 
TGGGCTGTGA AAAAGATAAA TCCTTTATGC GATGATCATT ATCGAACTGT GTATCAGAAG 
AGACTAACTG ATGAAGCTAA GATTTTAAAA AACCTTAATC ACCCAAACAT TGTAGGCTAT 
CGTGCTTTTA CTGAAGCCAG TGATGGTAGT CTGTGCCTTG CTATGGAGTA TGGAGGTGAA 
AAGTCTCTGA ATGACTTAAT AGAAGAGCGG AACAAAGACA GTGGAAGTCC TTTTCCAGCA 
GCTGTAATTC TCAGAGTTGC TTTGCACATG GCAAGAGGGC TAAAGTATCT GCATCAGGAA 
AAGAAGCTGC TGCATGGAGA CATAAAGTCT TCAAATGTTG TAATTAAAGG TGACTTTGAA 
ACAATTAAAA TCTGTGATGT AGGAGTCTCT CTGCCATTGG ATGAAAATAT GACTGTGACT 
GATCCTGAGG CCTGTTATAT TGGTACTGAG CCATGGAAAC CCAAAGAAGC ATTGGAGGAA 
AATGGCATTA TTACTGACAA GGCAGATATG TTTGCTTTTG GCCTTACTCT TTGGGAAATG 
ATGACTTTAT GTATTCCACA CATCAACCTT CCAGATGATG ATGATGATGA AGATGCAACA 
TTTGATGAGA GTGACTTCGA TGATGAAGCT TACTATGCAG CTCTGGGGAC AAGACCATCC 
ATCAATATGG AAGAACTGGA TGAATCCTAC CAGAAGGTCA TTGAACTCTT CTGTGTGTGT 
ACTAATGAGG ATCCTAAAGA TCGCCCATCT GCTGCACACA TCGTTGAAGC TTTGGAACTA 
GATGGCCAAT GTTGTGGTCT AAGCTCGAAG CATAGCTTGT ATGGGAACTG TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Pbk ( XM_006252105.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006252167.1 Rattus norvegicus PDZ binding kinase (Pbk), transcript variant X4, mRNA.

Price & Availability↑

CloneID	ORa10604
Clone ID Related Accession (Same CDS sequence)	XM_006252105.2 , NM_001079937.1 , XM_006252106.3 , XM_006252104.3 , XM_006252103.3
Accession Version	XM_006252105.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1014bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	lymphokine-activated killer T-cell-originated protein kinase isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005114.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 7, 2014 this sequence version replaced XM_006252105.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAAGGAA TCAGTAATTT CAAGACGCCA AACAAATTAT CTGAAAAAAG GAAATCTGTA 
TTATGTTCAA CTCCATGTGT AAATATCCCT GCCTCTCCAT TTATGCAGAA GCTCGGCTTT 
GGGACTGGGG TCAGTGTTTA CCTAATGAAA AGATCTCCGA GAGGGTTGTC CCATTCTCCT 
TGGGCTGTGA AAAAGATAAA TCCTTTATGC GATGATCATT ATCGAACTGT GTATCAGAAG 
AGACTAACTG ATGAAGCTAA GATTTTAAAA AACCTTAATC ACCCAAACAT TGTAGGCTAT 
CGTGCTTTTA CTGAAGCCAG TGATGGTAGT CTGTGCCTTG CTATGGAGTA TGGAGGTGAA 
AAGTCTCTGA ATGACTTAAT AGAAGAGCGG AACAAAGACA GTGGAAGTCC TTTTCCAGCA 
GCTGTAATTC TCAGAGTTGC TTTGCACATG GCAAGAGGGC TAAAGTATCT GCATCAGGAA 
AAGAAGCTGC TGCATGGAGA CATAAAGTCT TCAAATGTTG TAATTAAAGG TGACTTTGAA 
ACAATTAAAA TCTGTGATGT AGGAGTCTCT CTGCCATTGG ATGAAAATAT GACTGTGACT 
GATCCTGAGG CCTGTTATAT TGGTACTGAG CCATGGAAAC CCAAAGAAGC ATTGGAGGAA 
AATGGCATTA TTACTGACAA GGCAGATATG TTTGCTTTTG GCCTTACTCT TTGGGAAATG 
ATGACTTTAT GTATTCCACA CATCAACCTT CCAGATGATG ATGATGATGA AGATGCAACA 
TTTGATGAGA GTGACTTCGA TGATGAAGCT TACTATGCAG CTCTGGGGAC AAGACCATCC 
ATCAATATGG AAGAACTGGA TGAATCCTAC CAGAAGGTCA TTGAACTCTT CTGTGTGTGT 
ACTAATGAGG ATCCTAAAGA TCGCCCATCT GCTGCACACA TCGTTGAAGC TTTGGAACTA 
GATGGCCAAT GTTGTGGTCT AAGCTCGAAG CATAGCTTGT ATGGGAACTG TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006252167.1
CDS	389..1402
Translation	MEGISNFKTPNKLSEKRKSVLCSTPCVNIPASPFMQKLGFGTGVSVYLMKRSPRGLSHSPWAVKKINPLCDDHYRTVYQKRLTDEAKILKNLNHPNIVGYRAFTEASDGSLCLAMEYGGEKSLNDLIEERNKDSGSPFPAAVILRVALHMARGLKYLHQEKKLLHGDIKSSNVVIKGDFETIKICDVGVSLPLDENMTVTDPEACYIGTEPWKPKEALEENGIITDKADMFAFGLTLWEMMTLCIPHINLPDDDDDEDATFDESDFDDEAYYAALGTRPSINMEELDESYQKVIELFCVCTNEDPKDRPSAAHIVEALELDGQCCGLSSKHSLYGNC

Target ORF information:

RefSeq Version	XM_006252105.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus PDZ binding kinase (Pbk), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006252105.2

ORF Insert Sequence:

ATGGAAGGAA TCAGTAATTT CAAGACGCCA AACAAATTAT CTGAAAAAAG GAAATCTGTA 
TTATGTTCAA CTCCATGTGT AAATATCCCT GCCTCTCCAT TTATGCAGAA GCTCGGCTTT 
GGGACTGGGG TCAGTGTTTA CCTAATGAAA AGATCTCCGA GAGGGTTGTC CCATTCTCCT 
TGGGCTGTGA AAAAGATAAA TCCTTTATGC GATGATCATT ATCGAACTGT GTATCAGAAG 
AGACTAACTG ATGAAGCTAA GATTTTAAAA AACCTTAATC ACCCAAACAT TGTAGGCTAT 
CGTGCTTTTA CTGAAGCCAG TGATGGTAGT CTGTGCCTTG CTATGGAGTA TGGAGGTGAA 
AAGTCTCTGA ATGACTTAAT AGAAGAGCGG AACAAAGACA GTGGAAGTCC TTTTCCAGCA 
GCTGTAATTC TCAGAGTTGC TTTGCACATG GCAAGAGGGC TAAAGTATCT GCATCAGGAA 
AAGAAGCTGC TGCATGGAGA CATAAAGTCT TCAAATGTTG TAATTAAAGG TGACTTTGAA 
ACAATTAAAA TCTGTGATGT AGGAGTCTCT CTGCCATTGG ATGAAAATAT GACTGTGACT 
GATCCTGAGG CCTGTTATAT TGGTACTGAG CCATGGAAAC CCAAAGAAGC ATTGGAGGAA 
AATGGCATTA TTACTGACAA GGCAGATATG TTTGCTTTTG GCCTTACTCT TTGGGAAATG 
ATGACTTTAT GTATTCCACA CATCAACCTT CCAGATGATG ATGATGATGA AGATGCAACA 
TTTGATGAGA GTGACTTCGA TGATGAAGCT TACTATGCAG CTCTGGGGAC AAGACCATCC 
ATCAATATGG AAGAACTGGA TGAATCCTAC CAGAAGGTCA TTGAACTCTT CTGTGTGTGT 
ACTAATGAGG ATCCTAAAGA TCGCCCATCT GCTGCACACA TCGTTGAAGC TTTGGAACTA 
GATGGCCAAT GTTGTGGTCT AAGCTCGAAG CATAGCTTGT ATGGGAACTG TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Pbk ( XM_006252106.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006252168.1 Rattus norvegicus PDZ binding kinase (Pbk), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa10604
Clone ID Related Accession (Same CDS sequence)	XM_006252105.2 , NM_001079937.1 , XM_006252106.3 , XM_006252104.3 , XM_006252103.3
Accession Version	XM_006252106.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1014bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	lymphokine-activated killer T-cell-originated protein kinase isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005114.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006252106.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAAGGAA TCAGTAATTT CAAGACGCCA AACAAATTAT CTGAAAAAAG GAAATCTGTA 
TTATGTTCAA CTCCATGTGT AAATATCCCT GCCTCTCCAT TTATGCAGAA GCTCGGCTTT 
GGGACTGGGG TCAGTGTTTA CCTAATGAAA AGATCTCCGA GAGGGTTGTC CCATTCTCCT 
TGGGCTGTGA AAAAGATAAA TCCTTTATGC GATGATCATT ATCGAACTGT GTATCAGAAG 
AGACTAACTG ATGAAGCTAA GATTTTAAAA AACCTTAATC ACCCAAACAT TGTAGGCTAT 
CGTGCTTTTA CTGAAGCCAG TGATGGTAGT CTGTGCCTTG CTATGGAGTA TGGAGGTGAA 
AAGTCTCTGA ATGACTTAAT AGAAGAGCGG AACAAAGACA GTGGAAGTCC TTTTCCAGCA 
GCTGTAATTC TCAGAGTTGC TTTGCACATG GCAAGAGGGC TAAAGTATCT GCATCAGGAA 
AAGAAGCTGC TGCATGGAGA CATAAAGTCT TCAAATGTTG TAATTAAAGG TGACTTTGAA 
ACAATTAAAA TCTGTGATGT AGGAGTCTCT CTGCCATTGG ATGAAAATAT GACTGTGACT 
GATCCTGAGG CCTGTTATAT TGGTACTGAG CCATGGAAAC CCAAAGAAGC ATTGGAGGAA 
AATGGCATTA TTACTGACAA GGCAGATATG TTTGCTTTTG GCCTTACTCT TTGGGAAATG 
ATGACTTTAT GTATTCCACA CATCAACCTT CCAGATGATG ATGATGATGA AGATGCAACA 
TTTGATGAGA GTGACTTCGA TGATGAAGCT TACTATGCAG CTCTGGGGAC AAGACCATCC 
ATCAATATGG AAGAACTGGA TGAATCCTAC CAGAAGGTCA TTGAACTCTT CTGTGTGTGT 
ACTAATGAGG ATCCTAAAGA TCGCCCATCT GCTGCACACA TCGTTGAAGC TTTGGAACTA 
GATGGCCAAT GTTGTGGTCT AAGCTCGAAG CATAGCTTGT ATGGGAACTG TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006252168.1
CDS	330..1343
Translation	MEGISNFKTPNKLSEKRKSVLCSTPCVNIPASPFMQKLGFGTGVSVYLMKRSPRGLSHSPWAVKKINPLCDDHYRTVYQKRLTDEAKILKNLNHPNIVGYRAFTEASDGSLCLAMEYGGEKSLNDLIEERNKDSGSPFPAAVILRVALHMARGLKYLHQEKKLLHGDIKSSNVVIKGDFETIKICDVGVSLPLDENMTVTDPEACYIGTEPWKPKEALEENGIITDKADMFAFGLTLWEMMTLCIPHINLPDDDDDEDATFDESDFDDEAYYAALGTRPSINMEELDESYQKVIELFCVCTNEDPKDRPSAAHIVEALELDGQCCGLSSKHSLYGNC

Target ORF information:

RefSeq Version	XM_006252106.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus PDZ binding kinase (Pbk), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006252106.3

ORF Insert Sequence:

ATGGAAGGAA TCAGTAATTT CAAGACGCCA AACAAATTAT CTGAAAAAAG GAAATCTGTA 
TTATGTTCAA CTCCATGTGT AAATATCCCT GCCTCTCCAT TTATGCAGAA GCTCGGCTTT 
GGGACTGGGG TCAGTGTTTA CCTAATGAAA AGATCTCCGA GAGGGTTGTC CCATTCTCCT 
TGGGCTGTGA AAAAGATAAA TCCTTTATGC GATGATCATT ATCGAACTGT GTATCAGAAG 
AGACTAACTG ATGAAGCTAA GATTTTAAAA AACCTTAATC ACCCAAACAT TGTAGGCTAT 
CGTGCTTTTA CTGAAGCCAG TGATGGTAGT CTGTGCCTTG CTATGGAGTA TGGAGGTGAA 
AAGTCTCTGA ATGACTTAAT AGAAGAGCGG AACAAAGACA GTGGAAGTCC TTTTCCAGCA 
GCTGTAATTC TCAGAGTTGC TTTGCACATG GCAAGAGGGC TAAAGTATCT GCATCAGGAA 
AAGAAGCTGC TGCATGGAGA CATAAAGTCT TCAAATGTTG TAATTAAAGG TGACTTTGAA 
ACAATTAAAA TCTGTGATGT AGGAGTCTCT CTGCCATTGG ATGAAAATAT GACTGTGACT 
GATCCTGAGG CCTGTTATAT TGGTACTGAG CCATGGAAAC CCAAAGAAGC ATTGGAGGAA 
AATGGCATTA TTACTGACAA GGCAGATATG TTTGCTTTTG GCCTTACTCT TTGGGAAATG 
ATGACTTTAT GTATTCCACA CATCAACCTT CCAGATGATG ATGATGATGA AGATGCAACA 
TTTGATGAGA GTGACTTCGA TGATGAAGCT TACTATGCAG CTCTGGGGAC AAGACCATCC 
ATCAATATGG AAGAACTGGA TGAATCCTAC CAGAAGGTCA TTGAACTCTT CTGTGTGTGT 
ACTAATGAGG ATCCTAAAGA TCGCCCATCT GCTGCACACA TCGTTGAAGC TTTGGAACTA 
GATGGCCAAT GTTGTGGTCT AAGCTCGAAG CATAGCTTGT ATGGGAACTG TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Pbk ( XM_006252104.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006252166.1 Rattus norvegicus PDZ binding kinase (Pbk), transcript variant X3, mRNA.

Price & Availability↑

CloneID	ORa10604
Clone ID Related Accession (Same CDS sequence)	XM_006252105.2 , NM_001079937.1 , XM_006252106.3 , XM_006252104.3 , XM_006252103.3
Accession Version	XM_006252104.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1014bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	lymphokine-activated killer T-cell-originated protein kinase isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005114.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006252104.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAAGGAA TCAGTAATTT CAAGACGCCA AACAAATTAT CTGAAAAAAG GAAATCTGTA 
TTATGTTCAA CTCCATGTGT AAATATCCCT GCCTCTCCAT TTATGCAGAA GCTCGGCTTT 
GGGACTGGGG TCAGTGTTTA CCTAATGAAA AGATCTCCGA GAGGGTTGTC CCATTCTCCT 
TGGGCTGTGA AAAAGATAAA TCCTTTATGC GATGATCATT ATCGAACTGT GTATCAGAAG 
AGACTAACTG ATGAAGCTAA GATTTTAAAA AACCTTAATC ACCCAAACAT TGTAGGCTAT 
CGTGCTTTTA CTGAAGCCAG TGATGGTAGT CTGTGCCTTG CTATGGAGTA TGGAGGTGAA 
AAGTCTCTGA ATGACTTAAT AGAAGAGCGG AACAAAGACA GTGGAAGTCC TTTTCCAGCA 
GCTGTAATTC TCAGAGTTGC TTTGCACATG GCAAGAGGGC TAAAGTATCT GCATCAGGAA 
AAGAAGCTGC TGCATGGAGA CATAAAGTCT TCAAATGTTG TAATTAAAGG TGACTTTGAA 
ACAATTAAAA TCTGTGATGT AGGAGTCTCT CTGCCATTGG ATGAAAATAT GACTGTGACT 
GATCCTGAGG CCTGTTATAT TGGTACTGAG CCATGGAAAC CCAAAGAAGC ATTGGAGGAA 
AATGGCATTA TTACTGACAA GGCAGATATG TTTGCTTTTG GCCTTACTCT TTGGGAAATG 
ATGACTTTAT GTATTCCACA CATCAACCTT CCAGATGATG ATGATGATGA AGATGCAACA 
TTTGATGAGA GTGACTTCGA TGATGAAGCT TACTATGCAG CTCTGGGGAC AAGACCATCC 
ATCAATATGG AAGAACTGGA TGAATCCTAC CAGAAGGTCA TTGAACTCTT CTGTGTGTGT 
ACTAATGAGG ATCCTAAAGA TCGCCCATCT GCTGCACACA TCGTTGAAGC TTTGGAACTA 
GATGGCCAAT GTTGTGGTCT AAGCTCGAAG CATAGCTTGT ATGGGAACTG TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006252166.1
CDS	116..1129
Translation	MEGISNFKTPNKLSEKRKSVLCSTPCVNIPASPFMQKLGFGTGVSVYLMKRSPRGLSHSPWAVKKINPLCDDHYRTVYQKRLTDEAKILKNLNHPNIVGYRAFTEASDGSLCLAMEYGGEKSLNDLIEERNKDSGSPFPAAVILRVALHMARGLKYLHQEKKLLHGDIKSSNVVIKGDFETIKICDVGVSLPLDENMTVTDPEACYIGTEPWKPKEALEENGIITDKADMFAFGLTLWEMMTLCIPHINLPDDDDDEDATFDESDFDDEAYYAALGTRPSINMEELDESYQKVIELFCVCTNEDPKDRPSAAHIVEALELDGQCCGLSSKHSLYGNC

Target ORF information:

RefSeq Version	XM_006252104.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus PDZ binding kinase (Pbk), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006252104.3

ORF Insert Sequence:

ATGGAAGGAA TCAGTAATTT CAAGACGCCA AACAAATTAT CTGAAAAAAG GAAATCTGTA 
TTATGTTCAA CTCCATGTGT AAATATCCCT GCCTCTCCAT TTATGCAGAA GCTCGGCTTT 
GGGACTGGGG TCAGTGTTTA CCTAATGAAA AGATCTCCGA GAGGGTTGTC CCATTCTCCT 
TGGGCTGTGA AAAAGATAAA TCCTTTATGC GATGATCATT ATCGAACTGT GTATCAGAAG 
AGACTAACTG ATGAAGCTAA GATTTTAAAA AACCTTAATC ACCCAAACAT TGTAGGCTAT 
CGTGCTTTTA CTGAAGCCAG TGATGGTAGT CTGTGCCTTG CTATGGAGTA TGGAGGTGAA 
AAGTCTCTGA ATGACTTAAT AGAAGAGCGG AACAAAGACA GTGGAAGTCC TTTTCCAGCA 
GCTGTAATTC TCAGAGTTGC TTTGCACATG GCAAGAGGGC TAAAGTATCT GCATCAGGAA 
AAGAAGCTGC TGCATGGAGA CATAAAGTCT TCAAATGTTG TAATTAAAGG TGACTTTGAA 
ACAATTAAAA TCTGTGATGT AGGAGTCTCT CTGCCATTGG ATGAAAATAT GACTGTGACT 
GATCCTGAGG CCTGTTATAT TGGTACTGAG CCATGGAAAC CCAAAGAAGC ATTGGAGGAA 
AATGGCATTA TTACTGACAA GGCAGATATG TTTGCTTTTG GCCTTACTCT TTGGGAAATG 
ATGACTTTAT GTATTCCACA CATCAACCTT CCAGATGATG ATGATGATGA AGATGCAACA 
TTTGATGAGA GTGACTTCGA TGATGAAGCT TACTATGCAG CTCTGGGGAC AAGACCATCC 
ATCAATATGG AAGAACTGGA TGAATCCTAC CAGAAGGTCA TTGAACTCTT CTGTGTGTGT 
ACTAATGAGG ATCCTAAAGA TCGCCCATCT GCTGCACACA TCGTTGAAGC TTTGGAACTA 
GATGGCCAAT GTTGTGGTCT AAGCTCGAAG CATAGCTTGT ATGGGAACTG TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Pbk ( XM_006252103.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006252165.1 Rattus norvegicus PDZ binding kinase (Pbk), transcript variant X2, mRNA.

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CloneID	ORa10604
Clone ID Related Accession (Same CDS sequence)	XM_006252105.2 , NM_001079937.1 , XM_006252106.3 , XM_006252104.3 , XM_006252103.3
Accession Version	XM_006252103.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1014bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	lymphokine-activated killer T-cell-originated protein kinase isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005114.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006252103.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAAGGAA TCAGTAATTT CAAGACGCCA AACAAATTAT CTGAAAAAAG GAAATCTGTA 
TTATGTTCAA CTCCATGTGT AAATATCCCT GCCTCTCCAT TTATGCAGAA GCTCGGCTTT 
GGGACTGGGG TCAGTGTTTA CCTAATGAAA AGATCTCCGA GAGGGTTGTC CCATTCTCCT 
TGGGCTGTGA AAAAGATAAA TCCTTTATGC GATGATCATT ATCGAACTGT GTATCAGAAG 
AGACTAACTG ATGAAGCTAA GATTTTAAAA AACCTTAATC ACCCAAACAT TGTAGGCTAT 
CGTGCTTTTA CTGAAGCCAG TGATGGTAGT CTGTGCCTTG CTATGGAGTA TGGAGGTGAA 
AAGTCTCTGA ATGACTTAAT AGAAGAGCGG AACAAAGACA GTGGAAGTCC TTTTCCAGCA 
GCTGTAATTC TCAGAGTTGC TTTGCACATG GCAAGAGGGC TAAAGTATCT GCATCAGGAA 
AAGAAGCTGC TGCATGGAGA CATAAAGTCT TCAAATGTTG TAATTAAAGG TGACTTTGAA 
ACAATTAAAA TCTGTGATGT AGGAGTCTCT CTGCCATTGG ATGAAAATAT GACTGTGACT 
GATCCTGAGG CCTGTTATAT TGGTACTGAG CCATGGAAAC CCAAAGAAGC ATTGGAGGAA 
AATGGCATTA TTACTGACAA GGCAGATATG TTTGCTTTTG GCCTTACTCT TTGGGAAATG 
ATGACTTTAT GTATTCCACA CATCAACCTT CCAGATGATG ATGATGATGA AGATGCAACA 
TTTGATGAGA GTGACTTCGA TGATGAAGCT TACTATGCAG CTCTGGGGAC AAGACCATCC 
ATCAATATGG AAGAACTGGA TGAATCCTAC CAGAAGGTCA TTGAACTCTT CTGTGTGTGT 
ACTAATGAGG ATCCTAAAGA TCGCCCATCT GCTGCACACA TCGTTGAAGC TTTGGAACTA 
GATGGCCAAT GTTGTGGTCT AAGCTCGAAG CATAGCTTGT ATGGGAACTG TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006252165.1
CDS	113..1126
Translation	MEGISNFKTPNKLSEKRKSVLCSTPCVNIPASPFMQKLGFGTGVSVYLMKRSPRGLSHSPWAVKKINPLCDDHYRTVYQKRLTDEAKILKNLNHPNIVGYRAFTEASDGSLCLAMEYGGEKSLNDLIEERNKDSGSPFPAAVILRVALHMARGLKYLHQEKKLLHGDIKSSNVVIKGDFETIKICDVGVSLPLDENMTVTDPEACYIGTEPWKPKEALEENGIITDKADMFAFGLTLWEMMTLCIPHINLPDDDDDEDATFDESDFDDEAYYAALGTRPSINMEELDESYQKVIELFCVCTNEDPKDRPSAAHIVEALELDGQCCGLSSKHSLYGNC

Target ORF information:

RefSeq Version	XM_006252103.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus PDZ binding kinase (Pbk), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006252103.3

ORF Insert Sequence:

ATGGAAGGAA TCAGTAATTT CAAGACGCCA AACAAATTAT CTGAAAAAAG GAAATCTGTA 
TTATGTTCAA CTCCATGTGT AAATATCCCT GCCTCTCCAT TTATGCAGAA GCTCGGCTTT 
GGGACTGGGG TCAGTGTTTA CCTAATGAAA AGATCTCCGA GAGGGTTGTC CCATTCTCCT 
TGGGCTGTGA AAAAGATAAA TCCTTTATGC GATGATCATT ATCGAACTGT GTATCAGAAG 
AGACTAACTG ATGAAGCTAA GATTTTAAAA AACCTTAATC ACCCAAACAT TGTAGGCTAT 
CGTGCTTTTA CTGAAGCCAG TGATGGTAGT CTGTGCCTTG CTATGGAGTA TGGAGGTGAA 
AAGTCTCTGA ATGACTTAAT AGAAGAGCGG AACAAAGACA GTGGAAGTCC TTTTCCAGCA 
GCTGTAATTC TCAGAGTTGC TTTGCACATG GCAAGAGGGC TAAAGTATCT GCATCAGGAA 
AAGAAGCTGC TGCATGGAGA CATAAAGTCT TCAAATGTTG TAATTAAAGG TGACTTTGAA 
ACAATTAAAA TCTGTGATGT AGGAGTCTCT CTGCCATTGG ATGAAAATAT GACTGTGACT 
GATCCTGAGG CCTGTTATAT TGGTACTGAG CCATGGAAAC CCAAAGAAGC ATTGGAGGAA 
AATGGCATTA TTACTGACAA GGCAGATATG TTTGCTTTTG GCCTTACTCT TTGGGAAATG 
ATGACTTTAT GTATTCCACA CATCAACCTT CCAGATGATG ATGATGATGA AGATGCAACA 
TTTGATGAGA GTGACTTCGA TGATGAAGCT TACTATGCAG CTCTGGGGAC AAGACCATCC 
ATCAATATGG AAGAACTGGA TGAATCCTAC CAGAAGGTCA TTGAACTCTT CTGTGTGTGT 
ACTAATGAGG ATCCTAAAGA TCGCCCATCT GCTGCACACA TCGTTGAAGC TTTGGAACTA 
GATGGCCAAT GTTGTGGTCT AAGCTCGAAG CATAGCTTGT ATGGGAACTG TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Identification of the oncogenic kinase TOPK/PBK as a master mitotic regulator of C2H2 zinc finger proteins.
Oncotarget6(3)1446-61(2015 Jan)
Rizkallah R,Batsomboon P,Dudley GB,Hurt MM

Activation of T-LAK-cell-originated protein kinase-mediated antioxidation protects against focal cerebral ischemia-reperfusion injury.
The FEBS journal281(19)4411-20(2014 Oct)
Zhao H,Wang R,Tao Z,Yan F,Gao L,Liu X,Wang N,Min L,Jia Y,Zhao Y,Ji X,Luo Y

T-LAK cell-originated protein kinase (TOPK) phosphorylation of MKP1 protein prevents solar ultraviolet light-induced inflammation through inhibition of the p38 protein signaling pathway.
The Journal of biological chemistry286(34)29601-9(2011 Aug)
Li S,Zhu F,Zykova T,Kim MO,Cho YY,Bode AM,Peng C,Ma W,Carper A,Langfald A,Dong Z

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Pbk cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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