Atf5 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Atf5
Entrez Gene ID	282840
Full Name	activating transcription factor 5
General protein information	Preferred Names activating transcription factor 5 Names cyclic AMP-dependent transcription factor ATF-5 cAMP-dependent transcription factor ATF-5 transcription factor ATFx
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 1 Map Location: 1q22
Summary	plays a role in inhibition of nerve growth factor-induced neuronal outgrowth and regulation of neurogenesis [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_017588845.1	XP_017444334.1	cyclic AMP-dependent transcription factor ATF-5 isoform X1
NM_172336.3	NP_758839.3	cyclic AMP-dependent transcription factor ATF-5
XM_006228980.2	XP_006229042.1	cyclic AMP-dependent transcription factor ATF-5 isoform X1

Pathways from BioSystems

Homologies

	LOC719150	XP_001115871.1
Homo sapiens (human)	ATF5	NP_036200.2
Pan troglodytes (chimpanzee)	ATF5	XP_001173538.1
Mus musculus (house mouse)	Atf5	NP_109618.1
Rattus norvegicus (Norway rat)	Atf5	NP_758839.3
Bos taurus (cattle)	ATF5	NP_001179351.1
Canis lupus familiaris (dog)	ATF5	XP_003638861.1

Gene Ontology
Bibliography

Related articles in PubMed

ATF5 Connects the Pericentriolar Materials to the Proximal End of the Mother Centriole.
Madarampalli B, Yuan Y, Liu D, Lengel K, Xu Y, Li G, Yang J, Liu X, Lu Z, Liu DX
Cell162(3)580-92(2015 Jul)

Stabilization of ATF5 by TAK1-Nemo-like kinase critically regulates the interleukin-1?-stimulated C/EBP signaling pathway.
Zhang ZY, Li SZ, Zhang HH, Wu QR, Gong J, Liang T, Gao L, Xing NN, Liu WB, Du RL, Zhang XD
Molecular and cellular biology35(5)778-88(2015 Mar)

p300-dependent acetylation of activating transcription factor 5 enhances C/EBP? transactivation of C/EBP? during 3T3-L1 differentiation.
Zhao Y, Zhang YD, Zhang YY, Qian SW, Zhang ZC, Li SF, Guo L, Liu Y, Wen B, Lei QY, Tang QQ, Li X
Molecular and cellular biology34(3)315-24(2014 Feb)

Transcription factor ATF5 is required for terminal differentiation and survival of olfactory sensory neurons.
Wang SZ, Ou J, Zhu LJ, Green MR
Proceedings of the National Academy of Sciences of the United States of America109(45)18589-94(2012 Nov)

Nucleophosmin (NPM1/B23) interacts with activating transcription factor 5 (ATF5) protein and promotes proteasome- and caspase-dependent ATF5 degradation in hepatocellular carcinoma cells.
Liu X, Liu D, Qian D, Dai J, An Y, Jiang S, Stanley B, Yang J, Wang B, Liu X, Liu DX
The Journal of biological chemistry287(23)19599-609(2012 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

an essential role for HSP70 in maintaining high levels of ATF5 expression in glioma cells and support the conclusion that ATF5 is an important substrate protein of HSP70 that mediates HSP70-promoted cell survival in glioma cells.
Title: HSP70 protein promotes survival of C6 and U87 glioma cells by inhibition of ATF5 degradation.

Identified a novel ATF5 consensus DNA binding sequence. Demonstrate in C6 glioma and MCF-7 breast cancer cells that ATF5 occupies this sequence and that ATF5 activates reporter gene expression driven by this site.
Title: Identification of a novel DNA binding site and a transcriptional target for activating transcription factor 5 in c6 glioma and mcf-7 breast cancer cells.

Results show that serum shock of PC12 cells triggered circadian expression of Atf5.
Title: Evidence for circadian regulation of activating transcription factor 5 but not tyrosine hydroxylase by the chromaffin cell clock.

Results indicat that ATF5 promoted H9c2 cell survival in heat shock stress at least through activation of Hsp27.
Title: ATF5 promotes cell survival through transcriptional activation of Hsp27 in H9c2 cells.

ATF5 blocks the differentiation of neuroprogenitor cells into neurons and must be downregulated to permit this process to occur.
Title: Regulated expression of ATF5 is required for the progression of neural progenitor cells to neurons.

The following Atf5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Atf5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa03336	NM_172336.3 Latest version!	Rattus norvegicus activating transcription factor 5 (Atf5), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
ORa03336	XM_017588845.1 Latest version!	Rattus norvegicus activating transcription factor 5 (Atf5), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
ORa03336	XM_006228980.2 Latest version!	Rattus norvegicus activating transcription factor 5 (Atf5), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Atf5 ( NM_172336.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_758839.3 Rattus norvegicus activating transcription factor 5 (Atf5), mRNA.

Price & Availability↑

CloneID	ORa03336
Clone ID Related Accession (Same CDS sequence)	XM_017588845.1 , NM_172336.3 , XM_006228980.2
Accession Version	NM_172336.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 846bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-23
Organism	Rattus norvegicus(Norway rat)
Product	cyclic AMP-dependent transcription factor ATF-5
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AY123225.1. On Jul 1, 2007 this sequence version replaced NM_172336.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY123225.1, CK366581.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGTCACTCC TGGCGACCCT GGGACTGGAG CTGGACAGGG CCCTGCTCCC AGCTAGCGGG 
CTGGGCTGGC TCGTAGACTA TGGGAAACTC CCCCTGGCCC CTGCCCCCCT GGGCCCCTAT 
GAGGTCCTTG GGGGTGCCCT GGAGGGCGGG CTTCCAGGGG GGGGAGAGCC CCTGGCAGGT 
GACGGCTTCT CTGATTGGAT GACCGAGCGG GTGGACTTCA CAGCCCTCCT TCCTCTGGAG 
GCCCCTCTGC CCCCAGGCAC TCTCCCCCCA CCCTCCCCTG CCCCCCCTGA CCTGGAAGCC 
ATGGCATCCC TACTCAAGAA GGAGCTAGAA CAGATGGAAG ACTTCTTCCT TGATGCCCCA 
CTCCTTCCAC CGCCCTCCCC ACCTCCACCC CCACCCCCAG CACCCTCTCT GCCCCTGCCC 
TTACCCTTGC CCACCTTTGA TCTCCCGCAG CCTCCTACCC TGGATACCCT GGACTTGCTA 
GCTGTTTACT GCCGCAGTGA GGCTGGGCCA GGGGATTCAG GCTTGACAAC CCTGCCTGTC 
CCCCAGCAGC CTCCTCCTCT GGCCCCTCTG CCTTCACCCT CCCGACCAGC CCCCTATCCT 
AGTCCTGCCA GCACCCGAGG GGACCGCAAG CAAAAGAAGA GAGACCAGAA TAAGTCAGCT 
GCTCTCAGGT ACCGCCAGAG GAAGCGGGCA GAGGGCGAGG CCCTGGAGGG CGAGTGCCAA 
GGGCTAGAGG CGCGGAATCG GGAGCTGAGG GAGAGGGCAG AGTCAGTGGA ACGGGAGATC 
CAGTATGTGA AGGATCTGCT AATTGAGGTG TATAAGGCAC GAAGCCAGAG GACCCGCAGT 
GCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_758839.3
CDS	18..863
Translation	MSLLATLGLELDRALLPASGLGWLVDYGKLPLAPAPLGPYEVLGGALEGGLPGGGEPLAGDGFSDWMTERVDFTALLPLEAPLPPGTLPPPSPAPPDLEAMASLLKKELEQMEDFFLDAPLLPPPSPPPPPPPAPSLPLPLPLPTFDLPQPPTLDTLDLLAVYCRSEAGPGDSGLTTLPVPQQPPPLAPLPSPSRPAPYPSPASTRGDRKQKKRDQNKSAALRYRQRKRAEGEALEGECQGLEARNRELRERAESVEREIQYVKDLLIEVYKARSQRTRSA

Target ORF information:

RefSeq Version	NM_172336.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus activating transcription factor 5 (Atf5), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_172336.3

ORF Insert Sequence:

ATGTCACTCC TGGCGACCCT GGGACTGGAG CTGGACAGGG CCCTGCTCCC AGCTAGCGGG 
CTGGGCTGGC TCGTAGACTA TGGGAAACTC CCCCTGGCCC CTGCCCCCCT GGGCCCCTAT 
GAGGTCCTTG GGGGTGCCCT GGAGGGCGGG CTTCCAGGGG GGGGAGAGCC CCTGGCAGGT 
GACGGCTTCT CTGATTGGAT GACCGAGCGG GTGGACTTCA CAGCCCTCCT TCCTCTGGAG 
GCCCCTCTGC CCCCAGGCAC TCTCCCCCCA CCCTCCCCTG CCCCCCCTGA CCTGGAAGCC 
ATGGCATCCC TACTCAAGAA GGAGCTAGAA CAGATGGAAG ACTTCTTCCT TGATGCCCCA 
CTCCTTCCAC CGCCCTCCCC ACCTCCACCC CCACCCCCAG CACCCTCTCT GCCCCTGCCC 
TTACCCTTGC CCACCTTTGA TCTCCCGCAG CCTCCTACCC TGGATACCCT GGACTTGCTA 
GCTGTTTACT GCCGCAGTGA GGCTGGGCCA GGGGATTCAG GCTTGACAAC CCTGCCTGTC 
CCCCAGCAGC CTCCTCCTCT GGCCCCTCTG CCTTCACCCT CCCGACCAGC CCCCTATCCT 
AGTCCTGCCA GCACCCGAGG GGACCGCAAG CAAAAGAAGA GAGACCAGAA TAAGTCAGCT 
GCTCTCAGGT ACCGCCAGAG GAAGCGGGCA GAGGGCGAGG CCCTGGAGGG CGAGTGCCAA 
GGGCTAGAGG CGCGGAATCG GGAGCTGAGG GAGAGGGCAG AGTCAGTGGA ACGGGAGATC 
CAGTATGTGA AGGATCTGCT AATTGAGGTG TATAAGGCAC GAAGCCAGAG GACCCGCAGT 
GCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Atf5 ( XM_017588845.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017444334.1 Rattus norvegicus activating transcription factor 5 (Atf5), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa03336
Clone ID Related Accession (Same CDS sequence)	XM_017588845.1 , NM_172336.3 , XM_006228980.2
Accession Version	XM_017588845.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 846bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	cyclic AMP-dependent transcription factor ATF-5 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCACTCC TGGCGACCCT GGGACTGGAG CTGGACAGGG CCCTGCTCCC AGCTAGCGGG 
CTGGGCTGGC TCGTAGACTA TGGGAAACTC CCCCTGGCCC CTGCCCCCCT GGGCCCCTAT 
GAGGTCCTTG GGGGTGCCCT GGAGGGCGGG CTTCCAGGGG GGGGAGAGCC CCTGGCAGGT 
GACGGCTTCT CTGATTGGAT GACCGAGCGG GTGGACTTCA CAGCCCTCCT TCCTCTGGAG 
GCCCCTCTGC CCCCAGGCAC TCTCCCCCCA CCCTCCCCTG CCCCCCCTGA CCTGGAAGCC 
ATGGCATCCC TACTCAAGAA GGAGCTAGAA CAGATGGAAG ACTTCTTCCT TGATGCCCCA 
CTCCTTCCAC CGCCCTCCCC ACCTCCACCC CCACCCCCAG CACCCTCTCT GCCCCTGCCC 
TTACCCTTGC CCACCTTTGA TCTCCCGCAG CCTCCTACCC TGGATACCCT GGACTTGCTA 
GCTGTTTACT GCCGCAGTGA GGCTGGGCCA GGGGATTCAG GCTTGACAAC CCTGCCTGTC 
CCCCAGCAGC CTCCTCCTCT GGCCCCTCTG CCTTCACCCT CCCGACCAGC CCCCTATCCT 
AGTCCTGCCA GCACCCGAGG GGACCGCAAG CAAAAGAAGA GAGACCAGAA TAAGTCAGCT 
GCTCTCAGGT ACCGCCAGAG GAAGCGGGCA GAGGGCGAGG CCCTGGAGGG CGAGTGCCAA 
GGGCTAGAGG CGCGGAATCG GGAGCTGAGG GAGAGGGCAG AGTCAGTGGA ACGGGAGATC 
CAGTATGTGA AGGATCTGCT AATTGAGGTG TATAAGGCAC GAAGCCAGAG GACCCGCAGT 
GCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017444334.1
CDS	210..1055
Translation	MSLLATLGLELDRALLPASGLGWLVDYGKLPLAPAPLGPYEVLGGALEGGLPGGGEPLAGDGFSDWMTERVDFTALLPLEAPLPPGTLPPPSPAPPDLEAMASLLKKELEQMEDFFLDAPLLPPPSPPPPPPPAPSLPLPLPLPTFDLPQPPTLDTLDLLAVYCRSEAGPGDSGLTTLPVPQQPPPLAPLPSPSRPAPYPSPASTRGDRKQKKRDQNKSAALRYRQRKRAEGEALEGECQGLEARNRELRERAESVEREIQYVKDLLIEVYKARSQRTRSA

Target ORF information:

RefSeq Version	XM_017588845.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus activating transcription factor 5 (Atf5), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017588845.1

ORF Insert Sequence:

ATGTCACTCC TGGCGACCCT GGGACTGGAG CTGGACAGGG CCCTGCTCCC AGCTAGCGGG 
CTGGGCTGGC TCGTAGACTA TGGGAAACTC CCCCTGGCCC CTGCCCCCCT GGGCCCCTAT 
GAGGTCCTTG GGGGTGCCCT GGAGGGCGGG CTTCCAGGGG GGGGAGAGCC CCTGGCAGGT 
GACGGCTTCT CTGATTGGAT GACCGAGCGG GTGGACTTCA CAGCCCTCCT TCCTCTGGAG 
GCCCCTCTGC CCCCAGGCAC TCTCCCCCCA CCCTCCCCTG CCCCCCCTGA CCTGGAAGCC 
ATGGCATCCC TACTCAAGAA GGAGCTAGAA CAGATGGAAG ACTTCTTCCT TGATGCCCCA 
CTCCTTCCAC CGCCCTCCCC ACCTCCACCC CCACCCCCAG CACCCTCTCT GCCCCTGCCC 
TTACCCTTGC CCACCTTTGA TCTCCCGCAG CCTCCTACCC TGGATACCCT GGACTTGCTA 
GCTGTTTACT GCCGCAGTGA GGCTGGGCCA GGGGATTCAG GCTTGACAAC CCTGCCTGTC 
CCCCAGCAGC CTCCTCCTCT GGCCCCTCTG CCTTCACCCT CCCGACCAGC CCCCTATCCT 
AGTCCTGCCA GCACCCGAGG GGACCGCAAG CAAAAGAAGA GAGACCAGAA TAAGTCAGCT 
GCTCTCAGGT ACCGCCAGAG GAAGCGGGCA GAGGGCGAGG CCCTGGAGGG CGAGTGCCAA 
GGGCTAGAGG CGCGGAATCG GGAGCTGAGG GAGAGGGCAG AGTCAGTGGA ACGGGAGATC 
CAGTATGTGA AGGATCTGCT AATTGAGGTG TATAAGGCAC GAAGCCAGAG GACCCGCAGT 
GCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Atf5 ( XM_006228980.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006229042.1 Rattus norvegicus activating transcription factor 5 (Atf5), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa03336
Clone ID Related Accession (Same CDS sequence)	XM_017588845.1 , NM_172336.3 , XM_006228980.2
Accession Version	XM_006228980.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 846bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	cyclic AMP-dependent transcription factor ATF-5 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006228980.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCACTCC TGGCGACCCT GGGACTGGAG CTGGACAGGG CCCTGCTCCC AGCTAGCGGG 
CTGGGCTGGC TCGTAGACTA TGGGAAACTC CCCCTGGCCC CTGCCCCCCT GGGCCCCTAT 
GAGGTCCTTG GGGGTGCCCT GGAGGGCGGG CTTCCAGGGG GGGGAGAGCC CCTGGCAGGT 
GACGGCTTCT CTGATTGGAT GACCGAGCGG GTGGACTTCA CAGCCCTCCT TCCTCTGGAG 
GCCCCTCTGC CCCCAGGCAC TCTCCCCCCA CCCTCCCCTG CCCCCCCTGA CCTGGAAGCC 
ATGGCATCCC TACTCAAGAA GGAGCTAGAA CAGATGGAAG ACTTCTTCCT TGATGCCCCA 
CTCCTTCCAC CGCCCTCCCC ACCTCCACCC CCACCCCCAG CACCCTCTCT GCCCCTGCCC 
TTACCCTTGC CCACCTTTGA TCTCCCGCAG CCTCCTACCC TGGATACCCT GGACTTGCTA 
GCTGTTTACT GCCGCAGTGA GGCTGGGCCA GGGGATTCAG GCTTGACAAC CCTGCCTGTC 
CCCCAGCAGC CTCCTCCTCT GGCCCCTCTG CCTTCACCCT CCCGACCAGC CCCCTATCCT 
AGTCCTGCCA GCACCCGAGG GGACCGCAAG CAAAAGAAGA GAGACCAGAA TAAGTCAGCT 
GCTCTCAGGT ACCGCCAGAG GAAGCGGGCA GAGGGCGAGG CCCTGGAGGG CGAGTGCCAA 
GGGCTAGAGG CGCGGAATCG GGAGCTGAGG GAGAGGGCAG AGTCAGTGGA ACGGGAGATC 
CAGTATGTGA AGGATCTGCT AATTGAGGTG TATAAGGCAC GAAGCCAGAG GACCCGCAGT 
GCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006229042.1
CDS	796..1641
Translation	MSLLATLGLELDRALLPASGLGWLVDYGKLPLAPAPLGPYEVLGGALEGGLPGGGEPLAGDGFSDWMTERVDFTALLPLEAPLPPGTLPPPSPAPPDLEAMASLLKKELEQMEDFFLDAPLLPPPSPPPPPPPAPSLPLPLPLPTFDLPQPPTLDTLDLLAVYCRSEAGPGDSGLTTLPVPQQPPPLAPLPSPSRPAPYPSPASTRGDRKQKKRDQNKSAALRYRQRKRAEGEALEGECQGLEARNRELRERAESVEREIQYVKDLLIEVYKARSQRTRSA

Target ORF information:

RefSeq Version	XM_006228980.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus activating transcription factor 5 (Atf5), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006228980.2

ORF Insert Sequence:

ATGTCACTCC TGGCGACCCT GGGACTGGAG CTGGACAGGG CCCTGCTCCC AGCTAGCGGG 
CTGGGCTGGC TCGTAGACTA TGGGAAACTC CCCCTGGCCC CTGCCCCCCT GGGCCCCTAT 
GAGGTCCTTG GGGGTGCCCT GGAGGGCGGG CTTCCAGGGG GGGGAGAGCC CCTGGCAGGT 
GACGGCTTCT CTGATTGGAT GACCGAGCGG GTGGACTTCA CAGCCCTCCT TCCTCTGGAG 
GCCCCTCTGC CCCCAGGCAC TCTCCCCCCA CCCTCCCCTG CCCCCCCTGA CCTGGAAGCC 
ATGGCATCCC TACTCAAGAA GGAGCTAGAA CAGATGGAAG ACTTCTTCCT TGATGCCCCA 
CTCCTTCCAC CGCCCTCCCC ACCTCCACCC CCACCCCCAG CACCCTCTCT GCCCCTGCCC 
TTACCCTTGC CCACCTTTGA TCTCCCGCAG CCTCCTACCC TGGATACCCT GGACTTGCTA 
GCTGTTTACT GCCGCAGTGA GGCTGGGCCA GGGGATTCAG GCTTGACAAC CCTGCCTGTC 
CCCCAGCAGC CTCCTCCTCT GGCCCCTCTG CCTTCACCCT CCCGACCAGC CCCCTATCCT 
AGTCCTGCCA GCACCCGAGG GGACCGCAAG CAAAAGAAGA GAGACCAGAA TAAGTCAGCT 
GCTCTCAGGT ACCGCCAGAG GAAGCGGGCA GAGGGCGAGG CCCTGGAGGG CGAGTGCCAA 
GGGCTAGAGG CGCGGAATCG GGAGCTGAGG GAGAGGGCAG AGTCAGTGGA ACGGGAGATC 
CAGTATGTGA AGGATCTGCT AATTGAGGTG TATAAGGCAC GAAGCCAGAG GACCCGCAGT 
GCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

ATF5 Connects the Pericentriolar Materials to the Proximal End of the Mother Centriole.
Cell162(3)580-92(2015 Jul)
Madarampalli B,Yuan Y,Liu D,Lengel K,Xu Y,Li G,Yang J,Liu X,Lu Z,Liu DX

Stabilization of ATF5 by TAK1-Nemo-like kinase critically regulates the interleukin-1?-stimulated C/EBP signaling pathway.
Molecular and cellular biology35(5)778-88(2015 Mar)
Zhang ZY,Li SZ,Zhang HH,Wu QR,Gong J,Liang T,Gao L,Xing NN,Liu WB,Du RL,Zhang XD

p300-dependent acetylation of activating transcription factor 5 enhances C/EBP? transactivation of C/EBP? during 3T3-L1 differentiation.
Molecular and cellular biology34(3)315-24(2014 Feb)
Zhao Y,Zhang YD,Zhang YY,Qian SW,Zhang ZC,Li SF,Guo L,Liu Y,Wen B,Lei QY,Tang QQ,Li X

Transcription factor ATF5 is required for terminal differentiation and survival of olfactory sensory neurons.
Proceedings of the National Academy of Sciences of the United States of America109(45)18589-94(2012 Nov)
Wang SZ,Ou J,Zhu LJ,Green MR

Nucleophosmin (NPM1/B23) interacts with activating transcription factor 5 (ATF5) protein and promotes proteasome- and caspase-dependent ATF5 degradation in hepatocellular carcinoma cells.
The Journal of biological chemistry287(23)19599-609(2012 Jun)
Liu X,Liu D,Qian D,Dai J,An Y,Jiang S,Stanley B,Yang J,Wang B,Liu X,Liu DX

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Atf5 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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