Slc6a15 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Slc6a15
Entrez Gene ID	282712
Full Name	solute carrier family 6 member 15
Synonyms	Ntt73
General protein information	Preferred Names solute carrier family 6 member 15 Names sodium-dependent neutral amino acid transporter B(0)AT2 orphan sodium- and chloride-dependent neurotransmitter transporter NTT73 orphan transporter v7-3 sodium- and chloride-dependent neurotransmitter transporter NTT73 solute carrier family 6 (neurotransmitter transporter), member 15 solute carrier family 6 (neutral amino acid transporter), member 15 transporter v7-3
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 7 Map Location: 7q21
Summary	human homolog is a sodium:neurotransmitter symporter [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_172321.1	NP_758824.1	sodium-dependent neutral amino acid transporter B(0)AT2

Pathways from BioSystems

Homologies

Gallus gallus (chicken)	SLC6A15	XP_004937654.1
Xenopus tropicalis (tropical clawed frog)	slc6a15	XP_004912967.1
Danio rerio (zebrafish)	slc6a15	NP_001232001.1
Homo sapiens (human)	SLC6A15	NP_877499.1
Mus musculus (house mouse)	Slc6a15	NP_001239259.1
Canis lupus familiaris (dog)	SLC6A15	XP_005629249.1
Bos taurus (cattle)	SLC6A15	NP_851366.1
Rattus norvegicus (Norway rat)	Slc6a15	NP_758824.1

Gene Ontology
Bibliography

Related articles in PubMed

Synaptic Vesicle Protein NTT4/XT1 (SLC6A17) Catalyzes Na+-coupled Neutral Amino Acid Transport.
Zaia KA, Reimer RJ
The Journal of biological chemistry284(13)8439-48(2009 Mar)

Deletion of v7-3 (SLC6A15) transporter allows assessment of its roles in synaptosomal proline uptake, leucine uptake and behaviors.
Drgonova J, Liu QR, Hall FS, Krieger RM, Uhl GR
Brain research118310-20(2007 Dec)

Characterization of a branched-chain amino-acid transporter SBAT1 (SLC6A15) that is expressed in human brain.
Takanaga H, Mackenzie B, Peng JB, Hediger MA
Biochemical and biophysical research communications337(3)892-900(2005 Nov)

Neurotransmitter transporter family cDNAs in a rat midbrain library: 'orphan transporters' suggest sizable structural variations.
Uhl GR, Kitayama S, Gregor P, Nanthakumar E, Persico A, Shimada S
Brain research. Molecular brain research16(3-4)353-9(1992 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The substrate profile of the NTT4/XT1-dependent activity is similar to that of the closely related B(0)AT2/SBAT1 (SLC6A15), including a submillimolar apparent affinity for proline and leucine and a low millimolar apparent affinity for glutamine.
Title: Synaptic Vesicle Protein NTT4/XT1 (SLC6A17) Catalyzes Na+-coupled Neutral Amino Acid Transport.

The following Slc6a15 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Slc6a15 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa03270	NM_172321.1 Latest version!	Rattus norvegicus solute carrier family 6 member 15 (Slc6a15), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Slc6a15 ( NM_172321.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_758824.1 Rattus norvegicus solute carrier family 6 member 15 (Slc6a15), mRNA.

Price & Availability↑

CloneID	ORa03270
Clone ID Related Accession (Same CDS sequence)	NM_172321.1
Accession Version	NM_172321.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2190bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-23
Organism	Rattus norvegicus(Norway rat)
Product	sodium-dependent neutral amino acid transporter B(0)AT2
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from L22022.1. ##Evidence-Data-START## Transcript exon combination :: L22022.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGCCTAAGA ATAGCAAAGT AGTAAAGAGA GATTTGGATG ATGATGTCAT TGAATCTGTC 
AAAGACCTCC TGTCCAATGA AGACTCAGTG GAAGATGTTT CTAAGAAGAG CGAACTAATT 
GTTGATGTTC AAGAAGAGAA AGATACAGAT GCTGAAGATG GATCTGAAGT TGATGATGAA 
AGGCCAGCTT GGAACAGTAA GCTGCAATAC ATCCTGGCGC AAGTTGGATT TTCTGTAGGT 
CTGGGGAATG TGTGGCGGTT CCCATACCTC TGCCAAAAGA ATGGCGGTGG TGCATATCTT 
TTGCCATATT TAATACTACT TCTGGTGATA GGAATTCCAC TCTTCTTCTT GGAACTTTCT 
GTGGGTCAAA GAATTCGGAG AGGCAGCATC GGGGTTTGGA ATTACATAAG CCCTAAACTG 
GGTGGGATTG GATTCGCAAG CTGTGTAGTG TGCTATTTTG TGGCTCTCTA CTACAATGTC 
ATCATTGGCT GGACATTGTT TTACTTTTCT CAGTCTTTTC AACAACCTCT CCCTTGGGAT 
CAATGCCCCC TGGTGAAAAA CGCATCTCAT ACTTATATTG AGCCAGAATG TGAAAAAAGT 
TCTGCCACCA CTTATTACTG GTACCGGGAA GCACTGGCTA TCAGCAGCTC CATCTCTGAA 
AGTGGGGGCT TAAACTGGAA GATGACTGGC TGCCTGCTGG CTGCCTGGGT CATGGTTTGT 
CTGGCCATGA TCAAAGGCAT TCAGTCCTCT GGAAAAATCA TGTATTTTAG TTCTCTGTTC 
CCCTACGTGG TACTTATATG CTTCCTAATA AGATCTCTCC TTTTAAATGG TTCAATTGAT 
GGCATCCGAC ACATGTTCAC CCCTAAGCTT GAAATGATGC TGGAGCCCAA GGTTTGGAGA 
GAGGCAGCGA CTCAAGTCTT CTTTGCCTTG GGTTTGGGAT TTGGTGGAGT CATCGCGTTT 
TCCAGTTACA ACAAGAGAGA CAACAACTGC CACTTCGACG CTGTCCTCGT GTCTTTTATC 
AACTTTTTCA CTTCAGTCCT GGCAACACTG GTGGTGTTCG CAGTTCTGGG GTTCAAAGCC 
AATATCGTAA ATGAAAAGTG CATTTCACAA AATTCTGAGA TGATCTTGAA ACTTTTGAAA 
ACGGGAAACG TTAGTTGGGA TGTCATTCCC CGTCACATCA ACCTTTCAGC TGTCACTGCG 
GAAGATTATC ATGTAGTTTA CGACATCATT CAAAAAGTGA AGGAGGAGGA GTTTGCTGTT 
CTCCATCTCA AAGCCTGTCA AATTGAGGAT GAGCTAAATA AAGCTGTGCA GGGCACTGGC 
TTGGCTTTCA TTGCCTTTAC AGAGGCCATG ACACATTTTC CTGCATCTCC CTTCTGGTCA 
GTGATGTTTT TCCTCATGCT GATAAATCTC GGGCTCGGCA GCATGTTTGG AACCATTGAA 
GGAATCATCA CTCCTGTTGT GGACACATTC AAAGTGAGGA AGGAAATACT CACCGTTATC 
TGTTGCCTCC TAGCATTTTG TATCGGCTTG ATGTTTGTGC AGCGCTCTGG AAATTACTTC 
GTTACAATGT TTGATGATTA TTCTGCCACA TTGCCTCTGT TAATCGTGGT CATCTTGGAG 
AATATTGCTG TAAGCTTCGT TTACGGCATA GATAAGTTTC TAGAAGACCT AACAGACATG 
TTAGGATTTG CTCCAAGCAA ATATTACTAT TACATGTGGA AATACATTTC TCCTCTAATG 
CTAGTAACAT TGTTAATAGC TAGCATTGTG AATATGGGAT TAAGTCCTCC GGGATATAAT 
GCATGGATCA AGGAGAAGGC ATCCGAAGAA TTTCTGAGCT ACCCGATGTG GGGGATGGTG 
GTCTGTTTCT CTCTGATGGT GCTGGCTATA CTTCCTGTCC CAGTCGTTTT CGTCATTCGT 
CGCTGCAACC TCATAGATGA TAGTTCTGGT AACTTGGCCT CTGTGACCTA TAAGAGAGGA 
AGAGTCCTGA AAGAACCCGT GAACTTAGAC GGAGATGATG CAAGCCTCAT TCACGGAAAG 
ATACCAAGTG AAATGTCGTC TCCAAATTTT GGTAAAAATA TCTATCGAAA ACAGAGTGGT 
TCTCCGACCC TGGACACTGC TCCCAATGGA CGCTATGGGA TTGGGTATTT GATGGCAGAT 
ATGCCAGATA TGCCCGAGTC TGACTTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_758824.1
CDS	890..3079
Translation	MPKNSKVVKRDLDDDVIESVKDLLSNEDSVEDVSKKSELIVDVQEEKDTDAEDGSEVDDERPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLLPYLILLLVIGIPLFFLELSVGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWTLFYFSQSFQQPLPWDQCPLVKNASHTYIEPECEKSSATTYYWYREALAISSSISESGGLNWKMTGCLLAAWVMVCLAMIKGIQSSGKIMYFSSLFPYVVLICFLIRSLLLNGSIDGIRHMFTPKLEMMLEPKVWREAATQVFFALGLGFGGVIAFSSYNKRDNNCHFDAVLVSFINFFTSVLATLVVFAVLGFKANIVNEKCISQNSEMILKLLKTGNVSWDVIPRHINLSAVTAEDYHVVYDIIQKVKEEEFAVLHLKACQIEDELNKAVQGTGLAFIAFTEAMTHFPASPFWSVMFFLMLINLGLGSMFGTIEGIITPVVDTFKVRKEILTVICCLLAFCIGLMFVQRSGNYFVTMFDDYSATLPLLIVVILENIAVSFVYGIDKFLEDLTDMLGFAPSKYYYYMWKYISPLMLVTLLIASIVNMGLSPPGYNAWIKEKASEEFLSYPMWGMVVCFSLMVLAILPVPVVFVIRRCNLIDDSSGNLASVTYKRGRVLKEPVNLDGDDASLIHGKIPSEMSSPNFGKNIYRKQSGSPTLDTAPNGRYGIGYLMADMPDMPESDL

Target ORF information:

RefSeq Version	NM_172321.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus solute carrier family 6 member 15 (Slc6a15), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_172321.1

ORF Insert Sequence:

ATGCCTAAGA ATAGCAAAGT AGTAAAGAGA GATTTGGATG ATGATGTCAT TGAATCTGTC 
AAAGACCTCC TGTCCAATGA AGACTCAGTG GAAGATGTTT CTAAGAAGAG CGAACTAATT 
GTTGATGTTC AAGAAGAGAA AGATACAGAT GCTGAAGATG GATCTGAAGT TGATGATGAA 
AGGCCAGCTT GGAACAGTAA GCTGCAATAC ATCCTGGCGC AAGTTGGATT TTCTGTAGGT 
CTGGGGAATG TGTGGCGGTT CCCATACCTC TGCCAAAAGA ATGGCGGTGG TGCATATCTT 
TTGCCATATT TAATACTACT TCTGGTGATA GGAATTCCAC TCTTCTTCTT GGAACTTTCT 
GTGGGTCAAA GAATTCGGAG AGGCAGCATC GGGGTTTGGA ATTACATAAG CCCTAAACTG 
GGTGGGATTG GATTCGCAAG CTGTGTAGTG TGCTATTTTG TGGCTCTCTA CTACAATGTC 
ATCATTGGCT GGACATTGTT TTACTTTTCT CAGTCTTTTC AACAACCTCT CCCTTGGGAT 
CAATGCCCCC TGGTGAAAAA CGCATCTCAT ACTTATATTG AGCCAGAATG TGAAAAAAGT 
TCTGCCACCA CTTATTACTG GTACCGGGAA GCACTGGCTA TCAGCAGCTC CATCTCTGAA 
AGTGGGGGCT TAAACTGGAA GATGACTGGC TGCCTGCTGG CTGCCTGGGT CATGGTTTGT 
CTGGCCATGA TCAAAGGCAT TCAGTCCTCT GGAAAAATCA TGTATTTTAG TTCTCTGTTC 
CCCTACGTGG TACTTATATG CTTCCTAATA AGATCTCTCC TTTTAAATGG TTCAATTGAT 
GGCATCCGAC ACATGTTCAC CCCTAAGCTT GAAATGATGC TGGAGCCCAA GGTTTGGAGA 
GAGGCAGCGA CTCAAGTCTT CTTTGCCTTG GGTTTGGGAT TTGGTGGAGT CATCGCGTTT 
TCCAGTTACA ACAAGAGAGA CAACAACTGC CACTTCGACG CTGTCCTCGT GTCTTTTATC 
AACTTTTTCA CTTCAGTCCT GGCAACACTG GTGGTGTTCG CAGTTCTGGG GTTCAAAGCC 
AATATCGTAA ATGAAAAGTG CATTTCACAA AATTCTGAGA TGATCTTGAA ACTTTTGAAA 
ACGGGAAACG TTAGTTGGGA TGTCATTCCC CGTCACATCA ACCTTTCAGC TGTCACTGCG 
GAAGATTATC ATGTAGTTTA CGACATCATT CAAAAAGTGA AGGAGGAGGA GTTTGCTGTT 
CTCCATCTCA AAGCCTGTCA AATTGAGGAT GAGCTAAATA AAGCTGTGCA GGGCACTGGC 
TTGGCTTTCA TTGCCTTTAC AGAGGCCATG ACACATTTTC CTGCATCTCC CTTCTGGTCA 
GTGATGTTTT TCCTCATGCT GATAAATCTC GGGCTCGGCA GCATGTTTGG AACCATTGAA 
GGAATCATCA CTCCTGTTGT GGACACATTC AAAGTGAGGA AGGAAATACT CACCGTTATC 
TGTTGCCTCC TAGCATTTTG TATCGGCTTG ATGTTTGTGC AGCGCTCTGG AAATTACTTC 
GTTACAATGT TTGATGATTA TTCTGCCACA TTGCCTCTGT TAATCGTGGT CATCTTGGAG 
AATATTGCTG TAAGCTTCGT TTACGGCATA GATAAGTTTC TAGAAGACCT AACAGACATG 
TTAGGATTTG CTCCAAGCAA ATATTACTAT TACATGTGGA AATACATTTC TCCTCTAATG 
CTAGTAACAT TGTTAATAGC TAGCATTGTG AATATGGGAT TAAGTCCTCC GGGATATAAT 
GCATGGATCA AGGAGAAGGC ATCCGAAGAA TTTCTGAGCT ACCCGATGTG GGGGATGGTG 
GTCTGTTTCT CTCTGATGGT GCTGGCTATA CTTCCTGTCC CAGTCGTTTT CGTCATTCGT 
CGCTGCAACC TCATAGATGA TAGTTCTGGT AACTTGGCCT CTGTGACCTA TAAGAGAGGA 
AGAGTCCTGA AAGAACCCGT GAACTTAGAC GGAGATGATG CAAGCCTCAT TCACGGAAAG 
ATACCAAGTG AAATGTCGTC TCCAAATTTT GGTAAAAATA TCTATCGAAA ACAGAGTGGT 
TCTCCGACCC TGGACACTGC TCCCAATGGA CGCTATGGGA TTGGGTATTT GATGGCAGAT 
ATGCCAGATA TGCCCGAGTC TGACTTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Synaptic Vesicle Protein NTT4/XT1 (SLC6A17) Catalyzes Na+-coupled Neutral Amino Acid Transport.
The Journal of biological chemistry284(13)8439-48(2009 Mar)
Zaia KA,Reimer RJ

Deletion of v7-3 (SLC6A15) transporter allows assessment of its roles in synaptosomal proline uptake, leucine uptake and behaviors.
Brain research118310-20(2007 Dec)
Drgonova J,Liu QR,Hall FS,Krieger RM,Uhl GR

Characterization of a branched-chain amino-acid transporter SBAT1 (SLC6A15) that is expressed in human brain.
Biochemical and biophysical research communications337(3)892-900(2005 Nov)
Takanaga H,Mackenzie B,Peng JB,Hediger MA

Neurotransmitter transporter family cDNAs in a rat midbrain library: 'orphan transporters' suggest sizable structural variations.
Brain research. Molecular brain research16(3-4)353-9(1992 Dec)
Uhl GR,Kitayama S,Gregor P,Nanthakumar E,Persico A,Shimada S

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Slc6a15 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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