Kcnq5 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Kcnq5
Entrez Gene ID	259273
Full Name	potassium voltage-gated channel subfamily Q member 5
Synonyms	Kcnq5l
General protein information	Preferred Names potassium voltage-gated channel subfamily Q member 5 Names potassium voltage-gated channel subfamily KQT member 5 potassium channel, voltage-gated KQT-like subfamily Q, member 5 potassium voltage-gated channel, KQT-like subfamily, member 5
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 9 Map Location: 9q13

mRNA and Protein(s)

mRNA	Protein	Name
NM_001134643.2	NP_001128115.2	potassium voltage-gated channel subfamily KQT member 5

Pathways from BioSystems

Homologies

Caenorhabditis elegans (roundworm)	kqt-1	NP_741819.1
Pan troglodytes (chimpanzee)	KCNQ5	XP_003311443.1
Mus musculus (house mouse)	Kcnq5	NP_076361.1
Danio rerio (zebrafish)	kcnq5b	XP_697081.4
Xenopus tropicalis (tropical clawed frog)	kcnq5	XP_002937201.2
Homo sapiens (human)	KCNQ5	NP_001153605.1
	KCNQ5	XP_002803832.1
Canis lupus familiaris (dog)	KCNQ5	XP_003431813.1
Bos taurus (cattle)	KCNQ5	XP_002690062.2
Gallus gallus (chicken)	KCNQ5	XP_004940489.1
Danio rerio (zebrafish)	kcnq5a	XP_684855.4
Rattus norvegicus (Norway rat)	Kcnq5	NP_001128115.2

Gene Ontology
Bibliography

Related articles in PubMed

Loss-of-Function and Gain-of-Function Mutations in KCNQ5 Cause Intellectual Disability or Epileptic Encephalopathy.
Lehman A, Thouta S, Mancini GMS, Naidu S, van Slegtenhorst M, McWalter K, Person R, Mwenifumbo J, Salvarinova R, , , Guella I, McKenzie MB, Datta A, Connolly MB, Kalkhoran SM, Poburko D, Friedman JM, Farrer MJ, Demos M, Desai S, Claydon T
American journal of human genetics101(1)65-74(2017 Jul)

Downregulation of KCNQ5 expression in the rat pulmonary vasculature of nitrofen-induced congenital diaphragmatic hernia.
Zimmer J, Takahashi T, Hofmann AD, Puri P
Journal of pediatric surgery52(5)702-705(2017 May)

Kv7 channels critically determine coronary artery reactivity: left-right differences and down-regulation by hyperglycaemia.
Morales-Cano D, Moreno L, Barreira B, Pandolfi R, Chamorro V, Jimenez R, Villamor E, Duarte J, Perez-Vizcaino F, Cogolludo A
Cardiovascular research106(1)98-108(2015 Apr)

Loss of auditory activity modifies the location of potassium channel KCNQ5 in auditory brainstem neurons.
Caminos E, Garcia-Pino E, Juiz JM
Journal of neuroscience research93(4)604-14(2015 Apr)

Functional assembly of Kv7.1/Kv7.5 channels with emerging properties on vascular muscle physiology.
Oliveras A, Roura-Ferrer M, Sol? L, de la Cruz A, Prieto A, Etxebarria A, Manils J, Morales-Cano D, Condom E, Soler C, Cogolludo A, Valenzuela C, Villarroel A, Comes N, Felipe A
Arteriosclerosis, thrombosis, and vascular biology34(7)1522-30(2014 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Downregulated pulmonary expression of KCNQ5 in rat nitrofen-induced congenital diaphragmatic hernia lungs suggests that this potassium channel may play an important role in the development of pulmonary hypertension in this model. KCNQ1 and KCNQ4 expression was not altered.
Title: Downregulation of KCNQ5 expression in the rat pulmonary vasculature of nitrofen-induced congenital diaphragmatic hernia.

The high expression and function of Kv7 channels in the left coronary artery and their down-regulation by diabetes critically determine the sensitivity to key regulators of coronary tone.
Title: Kv7 channels critically determine coronary artery reactivity: left-right differences and down-regulation by hyperglycaemia.

These results show that peripheral activity from auditory nerve afferents is necessary to maintain the subcellular distribution of KCNQ5 in synaptic endings of the auditory brainstem.
Title: Loss of auditory activity modifies the location of potassium channel KCNQ5 in auditory brainstem neurons.

Kv7.1/Kv7.5 form heterotetrameric channels increasing the diversity of structures which fine-tune blood vessel reactivity. The lipid raft localization of Kv7.1/Kv7.5 heteromers provides efficient spatial and temporal regulation of smooth muscle function.
Title: Functional assembly of Kv7.1/Kv7.5 channels with emerging properties on vascular muscle physiology.

In cerebral arteries, Kv7.4 and Kv7.5 proteins exist predominantly as a functional heterotetramer, which regulates intrinsic myogenicity and vasodilation attributed to CGRP.
Title: Contribution of kv7.4/kv7.5 heteromers to intrinsic and calcitonin gene-related peptide-induced cerebral reactivity.

The following Kcnq5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Kcnq5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa13646	NM_001134643.2 Latest version!	Rattus norvegicus potassium voltage-gated channel subfamily Q member 5 (Kcnq5), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$475.30 $679.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Kcnq5 ( NM_001134643.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001128115.2 Rattus norvegicus potassium voltage-gated channel subfamily Q member 5 (Kcnq5), mRNA.

Price & Availability↑

CloneID	ORa13646
Clone ID Related Accession (Same CDS sequence)	NM_001134643.2
Accession Version	NM_001134643.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2856bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-28
Organism	Rattus norvegicus(Norway rat)
Product	potassium voltage-gated channel subfamily KQT member 5
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AABR07067050.1, AI705051.1, BE103175.1, FQ084615.1, BF523361.1 and AABR07067042.1. On Sep 6, 2012 this sequence version replaced NM_001134643.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMN04563758 [ECO:0000348] ##Evidence-Data-END##

ATGCCCCGCC ACCACGCGGG AGGAGAGGAG GGCGGTGCCG CCGGGCTCTG GGTGAGGAGC 
GGCGCGGCGG CGGCGGCGGG TGGGGGGCGC CCGGGCAGCG GCATGAAGGA TGTGGAGTCC 
GGCCGCGGCA GGGTGCTGCT GAACTCGGCG GCCGCCAGGG GCGACGGCCT GCTGCTGCTC 
GGCACCCGCG CGGCGGCGCT CGGCGGAGGC GGCGGCGGCT TGAGAGAGAG CCGCCGGGGC 
AAGCAGGGGG CCCGGATGAG CCTGCTGGGG AAGCCGCTCT CCTACACCAG CAGCCAGAGC 
TGTCGGCGCA ACGTCAAGTA CCGGAGGGTG CAGAACTATC TGTACAACGT GCTGGAGAGA 
CCCCGCGGCT GGGCGTTCGT CTACCACGCG TTCGTTTTTC TCCTTGTGTT TGGTTGCTTG 
ATTTTGTCAG TGTTTTCTAC CATCCCTGAG CACACAAAGT TGGCTTCAAG TTGCCTCTTA 
ATTCTGGAGT TCGTGATGAT CGTTGTCTTT GGCTTGGAGT TCATCATTCG AATCTGGTCT 
GCAGGTTGCT GTTGTCGTTA TAGAGGATGG CAAGGGAGAC TGAGGTTTGC TCGAAAGCCT 
TTCTGTGTTA TAGATACCAT TGTTCTTATC GCTTCAATAG CAGTTGTTTC TGCAAAAACT 
CAGGGTAATA TTTTCGCCAC GTCAGCGCTC AGAAGTCTCC GGTTCCTACA GATCCTGCGT 
ATGGTGCGCA TGGACAGAAG GGGAGGGACC TGGAAGTTGC TGGGCTCCGT GGTTTACGCT 
CACAGCAAGG AATTAATCAC AGCCTGGTAC ATTGGATTTC TGGTTCTTAT TTTTTCATCC 
TTCCTTGTCT ATCTTGTGGA AAAAGATGCC AATAAAGAGT TTTCAACATA TGCGGATGCT 
CTCTGGTGGG GCACAATTAC ACTGACAACC ATTGGCTATG GAGACAAAAC ACCCCTAACT 
TGGCTGGGAA GATTGCTCTC TGCAGGCTTC GCCCTTCTTG GTATTTCTTT CTTTGCACTT 
CCTGCTGGCA TTCTTGGCTC AGGTTTTGCC TTAAAAGTAC AGGAACAGCA CCGCCAGAAG 
CATTTTGAGA AAAGAAGGAA CCCAGCTGCC AACCTCATCC AGTGTGTCTG GCGTAGCTAT 
GCAGCTGATG AGAAGTCGGT CTCCATCGCA ACCTGGAAGC CACATCTGAA GGCCTTGCAC 
ACCTGCAGCC CTACCAAGAA AGAACAAGGG GAGGCAGCAA GCAGTAAGTT CTGTAGTAAT 
AAGCAGAAGT TCTTCAGAAT GTACACCTCA CGGAAGCAGA GTCAGAAGCT GAGCTTTAAG 
GAGCGAGTGC GCATGGCTAG CCCAAGAGGC CAGAGCATTA AGAGCAGACA AGCATCGGTA 
GGTGACCGGA GATCCCCAAG CACTGACATC ACTGCTGAGG GCAGCCCCAC CAAAGTGCAG 
AAGAGCTGGA GCTTCAACGA CCGAACCCGC TTCAGGCCCT CACTACGCCT CAAGAGTTCC 
CAGCCGAAGA CGGTGATAGA CGCTGACACA GCCCTTGGCA TTGACGACGT ATACGATGAG 
AAAGGATGCC AGTGTGACGT GTCCGTGGAG GACCTCACCC CACCACTCAA AACCGTCATC 
CGAGCCATCA GAATCATGAA GTTTCATGTT GCAAAGCGGA AGTTTAAGGA AACATTACGC 
CCATATGATG TAAAGGATGT CATTGAGCAA TACTCTGCTG GCCATCTGGA CATGCTATGT 
AGAATTAAAA GCCTTCAAAC ACGCGTTGAT CAAATTCTTG GAAAAGGACA AATCACATCA 
GATAAAAAGA GCCGAGAGAA AATAACGGCA GAACACGAGA CAACGACAGA TGACCTCAGC 
ATGCTGGGCC GAGTTGTGAA GGTTGAAAAA CAGGTACAAT CCATTGAATC CAAGCTGGAC 
TGCTTGCTGG ATATCTACCA GCAGGTCCTC CGGAAAGGCT CTGCCTCGGC CCTCACTCTG 
ACGTCCTTCC AGATCCCGCC CTTTGAATGT GAACAGACCT CTGACTATCA AAGTCCCGTG 
GAGAGCAAAG ACCTGTCGAG CTCCGCGCAA AACAGTGGCT GCTTAAGCAG GTCAGCCAGT 
GCCAACATCT CAAGAGGCCT GCAGTTCATC CTAACGCCAA ATGAGTTCAG TGCCCAGACT 
TTCTACGCGC TTAGCCCTAC TATGCACAGC CAAACTACAC AGGTGCCAAT GAGTCAAAAC 
GACGGCTCCT CCGTGGTGGC CACCAATAAC CTTGCAAACC AAATAAGCGC CGCACCCAAG 
CCAGCAGCTC CAACAACTTT ACAGATCCCA CCTCCTCTCT CAGCCATCAA GCATCTATCC 
AGGCCGGAAC CCCTGCTGTC CAACCCCCCT GGCGTACACG AGAGTATTTC TGACGTCACC 
ACCTGCCTTG TTGCCTCCAA GGAAAACGTT CAGTTCGCCC AGTCAAACCT GACCAAGGAC 
CGTTCCCTGA GGAAAAGTTT TGACATGGGA GGGGAAACTC TGTTGTCCGT CCGCCCCATG 
GTGCCCAAGG ACTTGGGCAA ATCTCTGTCT GTACAAAACC TGATCAGATC GACAGAGGAA 
CTGAACTTAC AGTTTTCGGG CAGTGAGTCA AGTGGCTCTC GAGGCAGCCA AGATTTTTAT 
CCCAAGTGGA GAGAATCCAA ATTGTTTATA ACTGATGAGG AGGTCGGTGC CGAGGAGACA 
GAAACAGATA CTTTTGACGG CACCCCACCG CCTGCCGGGG AAGCTGCTTT CTCATCAGAT 
TCTCTAAGGA CTGGAAGGTC ACGGTCATCT CAGAACATTT GTAAGACGGG AGACAGTACG 
GATGCCCTCA GTTTGCCTCA CGTCAAACTG AACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001128115.2
CDS	177..3032
Translation	MPRHHAGGEEGGAAGLWVRSGAAAAAGGGRPGSGMKDVESGRGRVLLNSAAARGDGLLLLGTRAAALGGGGGGLRESRRGKQGARMSLLGKPLSYTSSQSCRRNVKYRRVQNYLYNVLERPRGWAFVYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKEFSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAANLIQCVWRSYAADEKSVSIATWKPHLKALHTCSPTKKEQGEAASSKFCSNKQKFFRMYTSRKQSQKLSFKERVRMASPRGQSIKSRQASVGDRRSPSTDITAEGSPTKVQKSWSFNDRTRFRPSLRLKSSQPKTVIDADTALGIDDVYDEKGCQCDVSVEDLTPPLKTVIRAIRIMKFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQITSDKKSREKITAEHETTTDDLSMLGRVVKVEKQVQSIESKLDCLLDIYQQVLRKGSASALTLTSFQIPPFECEQTSDYQSPVESKDLSSSAQNSGCLSRSASANISRGLQFILTPNEFSAQTFYALSPTMHSQTTQVPMSQNDGSSVVATNNLANQISAAPKPAAPTTLQIPPPLSAIKHLSRPEPLLSNPPGVHESISDVTTCLVASKENVQFAQSNLTKDRSLRKSFDMGGETLLSVRPMVPKDLGKSLSVQNLIRSTEELNLQFSGSESSGSRGSQDFYPKWRESKLFITDEEVGAEETETDTFDGTPPPAGEAAFSSDSLRTGRSRSSQNICKTGDSTDALSLPHVKLN

Target ORF information:

RefSeq Version	NM_001134643.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus potassium voltage-gated channel subfamily Q member 5 (Kcnq5), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001134643.2

ORF Insert Sequence:

ATGCCCCGCC ACCACGCGGG AGGAGAGGAG GGCGGTGCCG CCGGGCTCTG GGTGAGGAGC 
GGCGCGGCGG CGGCGGCGGG TGGGGGGCGC CCGGGCAGCG GCATGAAGGA TGTGGAGTCC 
GGCCGCGGCA GGGTGCTGCT GAACTCGGCG GCCGCCAGGG GCGACGGCCT GCTGCTGCTC 
GGCACCCGCG CGGCGGCGCT CGGCGGAGGC GGCGGCGGCT TGAGAGAGAG CCGCCGGGGC 
AAGCAGGGGG CCCGGATGAG CCTGCTGGGG AAGCCGCTCT CCTACACCAG CAGCCAGAGC 
TGTCGGCGCA ACGTCAAGTA CCGGAGGGTG CAGAACTATC TGTACAACGT GCTGGAGAGA 
CCCCGCGGCT GGGCGTTCGT CTACCACGCG TTCGTTTTTC TCCTTGTGTT TGGTTGCTTG 
ATTTTGTCAG TGTTTTCTAC CATCCCTGAG CACACAAAGT TGGCTTCAAG TTGCCTCTTA 
ATTCTGGAGT TCGTGATGAT CGTTGTCTTT GGCTTGGAGT TCATCATTCG AATCTGGTCT 
GCAGGTTGCT GTTGTCGTTA TAGAGGATGG CAAGGGAGAC TGAGGTTTGC TCGAAAGCCT 
TTCTGTGTTA TAGATACCAT TGTTCTTATC GCTTCAATAG CAGTTGTTTC TGCAAAAACT 
CAGGGTAATA TTTTCGCCAC GTCAGCGCTC AGAAGTCTCC GGTTCCTACA GATCCTGCGT 
ATGGTGCGCA TGGACAGAAG GGGAGGGACC TGGAAGTTGC TGGGCTCCGT GGTTTACGCT 
CACAGCAAGG AATTAATCAC AGCCTGGTAC ATTGGATTTC TGGTTCTTAT TTTTTCATCC 
TTCCTTGTCT ATCTTGTGGA AAAAGATGCC AATAAAGAGT TTTCAACATA TGCGGATGCT 
CTCTGGTGGG GCACAATTAC ACTGACAACC ATTGGCTATG GAGACAAAAC ACCCCTAACT 
TGGCTGGGAA GATTGCTCTC TGCAGGCTTC GCCCTTCTTG GTATTTCTTT CTTTGCACTT 
CCTGCTGGCA TTCTTGGCTC AGGTTTTGCC TTAAAAGTAC AGGAACAGCA CCGCCAGAAG 
CATTTTGAGA AAAGAAGGAA CCCAGCTGCC AACCTCATCC AGTGTGTCTG GCGTAGCTAT 
GCAGCTGATG AGAAGTCGGT CTCCATCGCA ACCTGGAAGC CACATCTGAA GGCCTTGCAC 
ACCTGCAGCC CTACCAAGAA AGAACAAGGG GAGGCAGCAA GCAGTAAGTT CTGTAGTAAT 
AAGCAGAAGT TCTTCAGAAT GTACACCTCA CGGAAGCAGA GTCAGAAGCT GAGCTTTAAG 
GAGCGAGTGC GCATGGCTAG CCCAAGAGGC CAGAGCATTA AGAGCAGACA AGCATCGGTA 
GGTGACCGGA GATCCCCAAG CACTGACATC ACTGCTGAGG GCAGCCCCAC CAAAGTGCAG 
AAGAGCTGGA GCTTCAACGA CCGAACCCGC TTCAGGCCCT CACTACGCCT CAAGAGTTCC 
CAGCCGAAGA CGGTGATAGA CGCTGACACA GCCCTTGGCA TTGACGACGT ATACGATGAG 
AAAGGATGCC AGTGTGACGT GTCCGTGGAG GACCTCACCC CACCACTCAA AACCGTCATC 
CGAGCCATCA GAATCATGAA GTTTCATGTT GCAAAGCGGA AGTTTAAGGA AACATTACGC 
CCATATGATG TAAAGGATGT CATTGAGCAA TACTCTGCTG GCCATCTGGA CATGCTATGT 
AGAATTAAAA GCCTTCAAAC ACGCGTTGAT CAAATTCTTG GAAAAGGACA AATCACATCA 
GATAAAAAGA GCCGAGAGAA AATAACGGCA GAACACGAGA CAACGACAGA TGACCTCAGC 
ATGCTGGGCC GAGTTGTGAA GGTTGAAAAA CAGGTACAAT CCATTGAATC CAAGCTGGAC 
TGCTTGCTGG ATATCTACCA GCAGGTCCTC CGGAAAGGCT CTGCCTCGGC CCTCACTCTG 
ACGTCCTTCC AGATCCCGCC CTTTGAATGT GAACAGACCT CTGACTATCA AAGTCCCGTG 
GAGAGCAAAG ACCTGTCGAG CTCCGCGCAA AACAGTGGCT GCTTAAGCAG GTCAGCCAGT 
GCCAACATCT CAAGAGGCCT GCAGTTCATC CTAACGCCAA ATGAGTTCAG TGCCCAGACT 
TTCTACGCGC TTAGCCCTAC TATGCACAGC CAAACTACAC AGGTGCCAAT GAGTCAAAAC 
GACGGCTCCT CCGTGGTGGC CACCAATAAC CTTGCAAACC AAATAAGCGC CGCACCCAAG 
CCAGCAGCTC CAACAACTTT ACAGATCCCA CCTCCTCTCT CAGCCATCAA GCATCTATCC 
AGGCCGGAAC CCCTGCTGTC CAACCCCCCT GGCGTACACG AGAGTATTTC TGACGTCACC 
ACCTGCCTTG TTGCCTCCAA GGAAAACGTT CAGTTCGCCC AGTCAAACCT GACCAAGGAC 
CGTTCCCTGA GGAAAAGTTT TGACATGGGA GGGGAAACTC TGTTGTCCGT CCGCCCCATG 
GTGCCCAAGG ACTTGGGCAA ATCTCTGTCT GTACAAAACC TGATCAGATC GACAGAGGAA 
CTGAACTTAC AGTTTTCGGG CAGTGAGTCA AGTGGCTCTC GAGGCAGCCA AGATTTTTAT 
CCCAAGTGGA GAGAATCCAA ATTGTTTATA ACTGATGAGG AGGTCGGTGC CGAGGAGACA 
GAAACAGATA CTTTTGACGG CACCCCACCG CCTGCCGGGG AAGCTGCTTT CTCATCAGAT 
TCTCTAAGGA CTGGAAGGTC ACGGTCATCT CAGAACATTT GTAAGACGGG AGACAGTACG 
GATGCCCTCA GTTTGCCTCA CGTCAAACTG AACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Loss-of-Function and Gain-of-Function Mutations in KCNQ5 Cause Intellectual Disability or Epileptic Encephalopathy.
American journal of human genetics101(1)65-74(2017 Jul)
Lehman A,Thouta S,Mancini GMS,Naidu S,van Slegtenhorst M,McWalter K,Person R,Mwenifumbo J,Salvarinova R,,,Guella I,McKenzie MB,Datta A,Connolly MB,Kalkhoran SM,Poburko D,Friedman JM,Farrer MJ,Demos M,Desai S,Claydon T

Downregulation of KCNQ5 expression in the rat pulmonary vasculature of nitrofen-induced congenital diaphragmatic hernia.
Journal of pediatric surgery52(5)702-705(2017 May)
Zimmer J,Takahashi T,Hofmann AD,Puri P

Kv7 channels critically determine coronary artery reactivity: left-right differences and down-regulation by hyperglycaemia.
Cardiovascular research106(1)98-108(2015 Apr)
Morales-Cano D,Moreno L,Barreira B,Pandolfi R,Chamorro V,Jimenez R,Villamor E,Duarte J,Perez-Vizcaino F,Cogolludo A

Loss of auditory activity modifies the location of potassium channel KCNQ5 in auditory brainstem neurons.
Journal of neuroscience research93(4)604-14(2015 Apr)
Caminos E,Garcia-Pino E,Juiz JM

Functional assembly of Kv7.1/Kv7.5 channels with emerging properties on vascular muscle physiology.
Arteriosclerosis, thrombosis, and vascular biology34(7)1522-30(2014 Jul)
Oliveras A,Roura-Ferrer M,Sol? L,de la Cruz A,Prieto A,Etxebarria A,Manils J,Morales-Cano D,Condom E,Soler C,Cogolludo A,Valenzuela C,Villarroel A,Comes N,Felipe A

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Kcnq5 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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