Cnga2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Cnga2
Entrez Gene ID	25411
Full Name	cyclic nucleotide gated channel alpha 2
Synonyms	Cncg4,OLFCH
General protein information	Preferred Names cyclic nucleotide gated channel alpha 2 Names cyclic nucleotide-gated olfactory channel CNG channel alpha-2 CNG-2 CNG2 cyclic nucleotide gated channel 4 cyclic nucleotide-gated cation channel 2 cyclic nucleotide-gated olfactory channel subunit OCNC1 cyclic nucleotide-gated olfactory channel-like
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 16 Map Location: 16q12.4
Summary	cyclic nucleotide-gated ion channel involved in signal transduction; may participate in neural communication and plasticity [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_012928.1	NP_037060.1	cyclic nucleotide-gated olfactory channel
XM_017588414.1	XP_017443903.1	cyclic nucleotide-gated olfactory channel isoform X1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	CNGA2	XP_529195.2
Bos taurus (cattle)	CNGA2	NP_001001139.1
Danio rerio (zebrafish)	cnga5	NP_001038211.1
Rattus norvegicus (Norway rat)	Cnga2	NP_037060.1
Xenopus tropicalis (tropical clawed frog)	cnga2	XP_002939246.1
	LOC704486	XP_001092844.2
Homo sapiens (human)	CNGA2	NP_005131.1
Canis lupus familiaris (dog)	CNGA2	XP_005642014.1
Mus musculus (house mouse)	Cnga2	NP_031750.2
Gallus gallus (chicken)	CNGA2	XP_001234866.3

Gene Ontology
Bibliography

Related articles in PubMed

'Smelling' the cerebrospinal fluid: olfactory signaling molecules are expressed in and mediate chemosensory signaling from the choroid plexus.
Gon?alves I, Hubbard PC, Tom?s J, Quintela T, Tavares G, Caria S, Barreiros D, Santos CR
The FEBS journal283(9)1748-66(2016 05)

Binding orientation and specificity of calmodulin to rat olfactory cyclic nucleotide-gated ion channel.
Irene D, Huang JW, Chung TY, Li FY, Tzen JT, Lin TH, Chyan CL
Journal of biomolecular structure & dynamics31(4)414-25(2013 Apr)

Differential regulation by cyclic nucleotides of the CNGA4 and CNGB1b subunits in olfactory cyclic nucleotide-gated channels.
Nache V, Zimmer T, Wongsamitkul N, Schmauder R, Kusch J, Reinhardt L, B?nigk W, Seifert R, Biskup C, Schwede F, Benndorf K
Science signaling5(232)ra48(2012 Jul)

Calcium signalling remodelling and disease.
Berridge MJ
Biochemical Society transactions40(2)297-309(2012 Apr)

Ca2+-activated Cl? currents are dispensable for olfaction.
Billig GM, P?l B, Fidzinski P, Jentsch TJ
Nature neuroscience14(6)763-9(2011 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The major components of the olfactory transduction pathway in the rat choroid plexus have been determined, including odorant receptors, Galphaolf, adenylate cyclase 3 and CNGA2.
Title: 'Smelling' the cerebrospinal fluid: olfactory signaling molecules are expressed in and mediate chemosensory signaling from the choroid plexus.

Data indicate that the two distinct CaM/OLFp complexes existed simultaneously with stable structures.
Title: Binding orientation and specificity of calmodulin to rat olfactory cyclic nucleotide-gated ion channel.

cGMP activated olfactory CNG channels by binding to the two CNGA2 subunits and the CNGA4 subunit.
Title: Differential regulation by cyclic nucleotides of the CNGA4 and CNGB1b subunits in olfactory cyclic nucleotide-gated channels.

Data show that Cnga2 is enriched in the ciliary membrane fraction.
Title: Scaffolding proteins in highly purified rat olfactory cilia membranes.

Cyclic nucleotide-gated channels (CNG1 and CNG2 A subunits) affect membrane potential and excitability of rat medial vestibular nucleus.
Title: Functional role of cyclic nucleotide-gated channels in rat medial vestibular nucleus neurons.

The following Cnga2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cnga2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa01346	NM_012928.1 Latest version!	Rattus norvegicus cyclic nucleotide gated channel alpha 2 (Cnga2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
ORa43107	XM_017588414.1 Latest version!	Rattus norvegicus cyclic nucleotide gated channel alpha 2 (Cnga2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Cnga2 ( NM_012928.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_037060.1 Rattus norvegicus cyclic nucleotide gated channel alpha 2 (Cnga2), mRNA.

Price & Availability↑

CloneID	ORa01346
Clone ID Related Accession (Same CDS sequence)	NM_012928.1
Accession Version	NM_012928.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1995bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-25
Organism	Rattus norvegicus(Norway rat)
Product	cyclic nucleotide-gated olfactory channel
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from X55519.1. On or before Aug 24, 2014 this sequence version replaced XM_008771338.1, XM_003751618.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: X55519.1 [ECO:0000332] ##Evidence-Data-END##

ATGATGACCG AAAAATCCAA TGGTGTGAAA AGCTCTCCAG CTAATAACCA TAACCATCAT 
CCTCCTCCTT CTATCAAGGC CAATGGCAAA GATGACCACA GGGCAGGAAG CAGACCACAG 
TCTGTGGCAG CTGATGATGA CACTTCTCCA GAACTACAAA GGCTGGCAGA GATGGATACC 
CCTCGGAGGG GGAGGGGTGG CTTCCAAAGG ATTGTTCGCC TGGTGGGGGT CATCAGGGAC 
TGGGCCAACA AGAATTTCCG TGAAGAGGAA CCAAGGCCTG ACTCCTTCCT AGAGCGTTTC 
CGTGGGCCAG AACTCCAGAC TGTGACAACC CATCAGGGGG ATGACAAAGG CGGCAAGGAC 
GGCGAGGGAA AGGGCACCAA AAAGAAATTT GAACTGTTTG TTTTGGACCC AGCCGGAGAC 
TGGTATTACC GTTGGTTGTT TGTCATTGCC ATGCCTGTTC TTTACAACTG GTGCCTGTTG 
GTGGCCAGAG CCTGCTTCAG TGATCTACAG AGAAACTATT TTGTGGTATG GCTGGTGCTG 
GACTACTTCT CAGACACTGT CTATATCGCA GACCTCATCA TTCGGCTGCG CACAGGCTTC 
CTAGAACAGG GGCTCTTGGT CAAAGATCCC AAGAAATTGC GAGACAACTA TATTCACACT 
TTGCAGTTCA AATTGGATGT GGCTTCTATC ATTCCCACTG ACCTTATCTA TTTTGCTGTG 
GGTATCCACA GCCCTGAGGT ACGCTTCAAC CGTCTATTAC ACTTTGCCCG TATGTTTGAG 
TTCTTTGACC GCACTGAGAC ACGCACCAGC TACCCCAACA TCTTCCGAAT CAGCAATCTG 
GTCCTTTACA TCTTGGTCAT CATCCACTGG AATGCTTGTA TTTATTATGT TATTTCTAAG 
TCCATTGGCT TTGGAGTTGA CACCTGGGTT TACCCCAACA TTACTGACCC TGAATATGGC 
TACCTGGCTA GAGAGTACAT TTACTGTCTT TACTGGTCCA CACTGACCCT CACCACCATT 
GGAGAGACAC CACCCCCTGT AAAGGATGAG GAGTACCTAT TTGTCATCTT TGACTTCTTG 
ATTGGTGTCC TCATCTTTGC CACTATTGTG GGAAATGTGG GCTCCATGAT CTCCAACATG 
AATGCCACAC GAGCAGAGTT CCAGGCCAAG ATTGATGCTG TCAAACACTA CATGCAGTTC 
CGAAAGGTCA GCAAAGACAT GGAAGCCAAG GTCATCAAAT GGTTTGACTA CTTGTGGACC 
AATAAGAAGA CAGTAGATGA ACGAGAAGTC CTCAAGAACC TGCCAGCAAA GCTCAGGGCT 
GAGATAGCCA TTAATGTTCA CTTGTCCACT CTGAAGAAAG TGCGCATATT CCAGGATTGT 
GAAGCTGGCC TACTGGTGGA ACTGGTACTG AAGCTTCGTC CTCAGGTCTT TAGTCCTGGA 
GATTATATTT GCCGTAAGGG GGACATTGGC AAGGAAATGT ACATCATCAA GGAGGGCAAG 
TTGGCAGTGG TAGCTGATGA TGGCGTGACT CAGTATGCCT TGCTCTCAGC TGGGAGCTGC 
TTTGGTGAGA TTAGTATCCT TAACATTAAG GGTAGCAAAA TGGGCAATCG ACGTACTGCT 
AATATCCGTA GCCTGGGCTA CTCAGATCTC TTCTGCTTGT CCAAGGACGA TCTTATGGAA 
GCTGTAACTG AGTATCCTGA TGCCAAGAAG GTCCTGGAGG AACGGGGTAG GGAGATCCTG 
ATGAAGGAAG GTCTACTGGA TGAGAATGAA GTGGCAGCTA GTATGGAGGT AGATGTTCAG 
GAGAAGCTGG AACAGTTGGA GACAAACATG GATACCTTGT ACACTCGCTT TGCCCGCCTG 
CTGGCTGAGT ACACTGGGGC CCAGCAGAAG CTCAAGCAAC GCATCACAGT GCTAGAGACC 
AAGATGAAAC AGAACCATGA GGATGATTAT CTATCAGATG GGATAAACAC TCCTGAGCCA 
ACTGCTGCTG AATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_037060.1
CDS	340..2334
Translation	MMTEKSNGVKSSPANNHNHHPPPSIKANGKDDHRAGSRPQSVAADDDTSPELQRLAEMDTPRRGRGGFQRIVRLVGVIRDWANKNFREEEPRPDSFLERFRGPELQTVTTHQGDDKGGKDGEGKGTKKKFELFVLDPAGDWYYRWLFVIAMPVLYNWCLLVARACFSDLQRNYFVVWLVLDYFSDTVYIADLIIRLRTGFLEQGLLVKDPKKLRDNYIHTLQFKLDVASIIPTDLIYFAVGIHSPEVRFNRLLHFARMFEFFDRTETRTSYPNIFRISNLVLYILVIIHWNACIYYVISKSIGFGVDTWVYPNITDPEYGYLAREYIYCLYWSTLTLTTIGETPPPVKDEEYLFVIFDFLIGVLIFATIVGNVGSMISNMNATRAEFQAKIDAVKHYMQFRKVSKDMEAKVIKWFDYLWTNKKTVDEREVLKNLPAKLRAEIAINVHLSTLKKVRIFQDCEAGLLVELVLKLRPQVFSPGDYICRKGDIGKEMYIIKEGKLAVVADDGVTQYALLSAGSCFGEISILNIKGSKMGNRRTANIRSLGYSDLFCLSKDDLMEAVTEYPDAKKVLEERGREILMKEGLLDENEVAASMEVDVQEKLEQLETNMDTLYTRFARLLAEYTGAQQKLKQRITVLETKMKQNHEDDYLSDGINTPEPTAAE

Target ORF information:

RefSeq Version	NM_012928.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus cyclic nucleotide gated channel alpha 2 (Cnga2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_012928.1

ORF Insert Sequence:

ATGATGACCG AAAAATCCAA TGGTGTGAAA AGCTCTCCAG CTAATAACCA TAACCATCAT 
CCTCCTCCTT CTATCAAGGC CAATGGCAAA GATGACCACA GGGCAGGAAG CAGACCACAG 
TCTGTGGCAG CTGATGATGA CACTTCTCCA GAACTACAAA GGCTGGCAGA GATGGATACC 
CCTCGGAGGG GGAGGGGTGG CTTCCAAAGG ATTGTTCGCC TGGTGGGGGT CATCAGGGAC 
TGGGCCAACA AGAATTTCCG TGAAGAGGAA CCAAGGCCTG ACTCCTTCCT AGAGCGTTTC 
CGTGGGCCAG AACTCCAGAC TGTGACAACC CATCAGGGGG ATGACAAAGG CGGCAAGGAC 
GGCGAGGGAA AGGGCACCAA AAAGAAATTT GAACTGTTTG TTTTGGACCC AGCCGGAGAC 
TGGTATTACC GTTGGTTGTT TGTCATTGCC ATGCCTGTTC TTTACAACTG GTGCCTGTTG 
GTGGCCAGAG CCTGCTTCAG TGATCTACAG AGAAACTATT TTGTGGTATG GCTGGTGCTG 
GACTACTTCT CAGACACTGT CTATATCGCA GACCTCATCA TTCGGCTGCG CACAGGCTTC 
CTAGAACAGG GGCTCTTGGT CAAAGATCCC AAGAAATTGC GAGACAACTA TATTCACACT 
TTGCAGTTCA AATTGGATGT GGCTTCTATC ATTCCCACTG ACCTTATCTA TTTTGCTGTG 
GGTATCCACA GCCCTGAGGT ACGCTTCAAC CGTCTATTAC ACTTTGCCCG TATGTTTGAG 
TTCTTTGACC GCACTGAGAC ACGCACCAGC TACCCCAACA TCTTCCGAAT CAGCAATCTG 
GTCCTTTACA TCTTGGTCAT CATCCACTGG AATGCTTGTA TTTATTATGT TATTTCTAAG 
TCCATTGGCT TTGGAGTTGA CACCTGGGTT TACCCCAACA TTACTGACCC TGAATATGGC 
TACCTGGCTA GAGAGTACAT TTACTGTCTT TACTGGTCCA CACTGACCCT CACCACCATT 
GGAGAGACAC CACCCCCTGT AAAGGATGAG GAGTACCTAT TTGTCATCTT TGACTTCTTG 
ATTGGTGTCC TCATCTTTGC CACTATTGTG GGAAATGTGG GCTCCATGAT CTCCAACATG 
AATGCCACAC GAGCAGAGTT CCAGGCCAAG ATTGATGCTG TCAAACACTA CATGCAGTTC 
CGAAAGGTCA GCAAAGACAT GGAAGCCAAG GTCATCAAAT GGTTTGACTA CTTGTGGACC 
AATAAGAAGA CAGTAGATGA ACGAGAAGTC CTCAAGAACC TGCCAGCAAA GCTCAGGGCT 
GAGATAGCCA TTAATGTTCA CTTGTCCACT CTGAAGAAAG TGCGCATATT CCAGGATTGT 
GAAGCTGGCC TACTGGTGGA ACTGGTACTG AAGCTTCGTC CTCAGGTCTT TAGTCCTGGA 
GATTATATTT GCCGTAAGGG GGACATTGGC AAGGAAATGT ACATCATCAA GGAGGGCAAG 
TTGGCAGTGG TAGCTGATGA TGGCGTGACT CAGTATGCCT TGCTCTCAGC TGGGAGCTGC 
TTTGGTGAGA TTAGTATCCT TAACATTAAG GGTAGCAAAA TGGGCAATCG ACGTACTGCT 
AATATCCGTA GCCTGGGCTA CTCAGATCTC TTCTGCTTGT CCAAGGACGA TCTTATGGAA 
GCTGTAACTG AGTATCCTGA TGCCAAGAAG GTCCTGGAGG AACGGGGTAG GGAGATCCTG 
ATGAAGGAAG GTCTACTGGA TGAGAATGAA GTGGCAGCTA GTATGGAGGT AGATGTTCAG 
GAGAAGCTGG AACAGTTGGA GACAAACATG GATACCTTGT ACACTCGCTT TGCCCGCCTG 
CTGGCTGAGT ACACTGGGGC CCAGCAGAAG CTCAAGCAAC GCATCACAGT GCTAGAGACC 
AAGATGAAAC AGAACCATGA GGATGATTAT CTATCAGATG GGATAAACAC TCCTGAGCCA 
ACTGCTGCTG AATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cnga2 ( XM_017588414.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017443903.1 Rattus norvegicus cyclic nucleotide gated channel alpha 2 (Cnga2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa43107
Clone ID Related Accession (Same CDS sequence)	XM_017588414.1
Accession Version	XM_017588414.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1995bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	cyclic nucleotide-gated olfactory channel isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_001084896.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATGACCG AAAAATCCAA TGGTGTGAAA AGCTCTCCAG CTAATAACCA TAACCATCAT 
CCTCCTCCTT CTATCAAGGC CAATGGCAAA GATGACCACA GGGCAGGAAG CAGACCACAG 
TCTGTGGCAG CTGATGATGA CACTTCCTCA GAACTACAAA GGCTGGCAGA GATGGATACC 
CCTCGGAGGG GGAGGGGTGG CTTCCAAAGG ATTGTTCGCC TGGTGGGGGT CATCAGGGAC 
TGGGCCAACA AGAATTTCCG TGAAGAGGAA CCAAGGCCTG ACTCCTTCCT AGAGCGTTTC 
CGTGGGCCAG AACTCCAGAC TGTGACAACC CATCAGGGGG ATGACAAAGG CGGCAAGGAC 
GGCGAGGGAA AGGGACCCTT TGCTAAATTT GAACTGTTTG TTTTGGACCC AGCCGGAGAC 
TGGTATTACC GTTGGTTGTT TGTCATTGCC ATGCCTGTTC TTTACAACTG GTGCCTGTTG 
GTGGCCAGAG CCTGCTTCAG TGATCTACAG AGAAACTATT TTGTGGTATG GCTGGTGCTG 
GACTACTTCT CAGACACTGT CTATATCGCA GACCTCATCA TTCGGCTGCG CACAGGCTTC 
CTAGAACAGG GGCTCTTGGT CAAAGATCCC AAGAAATTGC GAGACAACTA TATTCACACT 
TTGCAGTTCA AATTGGATGT GGCTTCTATC ATTCCCACTG ACCTTATCTA TTTTGCTGTG 
GGTATCCACA GCCCTGAGGT ACGCTTCAAC CGTCTATTAC ACTTTGCCCG TATGTTTGAG 
TTCTTTGACC GCACTGAGAC ACGCACCAGC TACCCCAACA TCTTCCGAAT CAGCAATCTG 
GTCCTTTACA TCTTGGTCAT CATCCACTGG AATGCTTGTA TTTATTATGT TATTTCTAAG 
TCCATTGGCT TTGGAGTTGA CACCTGGGTT TACCCCAACA TTACTGACCC TGAATATGGC 
TACCTGGCTA GAGAGTACAT TTACTGTCTT TACTGGTCCA CACTGACCCT CACCACCATT 
GGAGAGACAC CACCCCCTGT AAAGGATGAG GAGTACCTAT TTGTCATCTT TGACTTCTTG 
ATTGGTGTCC TCATCTTTGC CACTATTGTG GGAAATGTGG GCTCCATGAT CTCCAACATG 
AATGCCACAC GAGCAGAGTT CCAGGCCAAG ATTGATGCTG TCAAACACTA CATGCAGTTC 
CGAAAGGTCA GCAAAGACAT GGAAGCCAAG GTCATCAAAT GGTTTGACTA CTTGTGGACC 
AATAAGAAGA CAGTAGATGA ACGAGAAGTC CTCAAGAACC TGCCAGCAAA GCTCAGGGCT 
GAGATAGCCA TTAATGTTCA CTTGTCCACT CTGAAGAAAG TGCGCATATT CCAGGATTGT 
GAAGCTGGCC TACTGGTGGA ACTGGTACTG AAGCTTCGTC CTCAGGTCTT TAGTCCTGGA 
GATTATATTT GCCGTAAGGG GGACATTGGC AAGGAAATGT ACATCATCAA GGAGGGCAAG 
TTGGCAGTGG TAGCTGATGA TGGCGTGACT CAGTATGCCT TGCTCTCAGC TGGGAGCTGC 
TTTGGTGAGA TTAGTATCCT TAACATTAAG GGTAGCAAAA TGGGCAATCG ACGTACTGCT 
AATATCCGTA GCCTGGGCTA CTCAGATCTC TTCTGCTTGT CCAAGGACGA TCTTATGGAA 
GCTGTAACTG AGTATCCTGA TGCCAAGAAG GTCCTGGAGG AACGGGGTAG GGAGATCCTG 
ATGAAGGAAG GTCTACTGGA TGAGAATGAA GTGGCAGCTA GTATGGAGGT AGATGTTCAG 
GAGAAGCTGG AACAGTTGGA GACAAACATG GATACCTTGT ACACTCGCTT TGCCCGCCTG 
CTGGCTGAGT ACACTGGGGC CCAGCAGAAG CTCAAGCAAC GCATCACAGT GCTAGAGACC 
AAGATGAAAC AGAACCATGA GGATGATTAT CTATCAGATG GGATAAACAC TCCTGAGCCA 
ACTGCTGCTG AATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017443903.1
CDS	116..2110
Translation	MMTEKSNGVKSSPANNHNHHPPPSIKANGKDDHRAGSRPQSVAADDDTSSELQRLAEMDTPRRGRGGFQRIVRLVGVIRDWANKNFREEEPRPDSFLERFRGPELQTVTTHQGDDKGGKDGEGKGPFAKFELFVLDPAGDWYYRWLFVIAMPVLYNWCLLVARACFSDLQRNYFVVWLVLDYFSDTVYIADLIIRLRTGFLEQGLLVKDPKKLRDNYIHTLQFKLDVASIIPTDLIYFAVGIHSPEVRFNRLLHFARMFEFFDRTETRTSYPNIFRISNLVLYILVIIHWNACIYYVISKSIGFGVDTWVYPNITDPEYGYLAREYIYCLYWSTLTLTTIGETPPPVKDEEYLFVIFDFLIGVLIFATIVGNVGSMISNMNATRAEFQAKIDAVKHYMQFRKVSKDMEAKVIKWFDYLWTNKKTVDEREVLKNLPAKLRAEIAINVHLSTLKKVRIFQDCEAGLLVELVLKLRPQVFSPGDYICRKGDIGKEMYIIKEGKLAVVADDGVTQYALLSAGSCFGEISILNIKGSKMGNRRTANIRSLGYSDLFCLSKDDLMEAVTEYPDAKKVLEERGREILMKEGLLDENEVAASMEVDVQEKLEQLETNMDTLYTRFARLLAEYTGAQQKLKQRITVLETKMKQNHEDDYLSDGINTPEPTAAE

Target ORF information:

RefSeq Version	XM_017588414.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus cyclic nucleotide gated channel alpha 2 (Cnga2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017588414.1

ORF Insert Sequence:

ATGATGACCG AAAAATCCAA TGGTGTGAAA AGCTCTCCAG CTAATAACCA TAACCATCAT 
CCTCCTCCTT CTATCAAGGC CAATGGCAAA GATGACCACA GGGCAGGAAG CAGACCACAG 
TCTGTGGCAG CTGATGATGA CACTTCCTCA GAACTACAAA GGCTGGCAGA GATGGATACC 
CCTCGGAGGG GGAGGGGTGG CTTCCAAAGG ATTGTTCGCC TGGTGGGGGT CATCAGGGAC 
TGGGCCAACA AGAATTTCCG TGAAGAGGAA CCAAGGCCTG ACTCCTTCCT AGAGCGTTTC 
CGTGGGCCAG AACTCCAGAC TGTGACAACC CATCAGGGGG ATGACAAAGG CGGCAAGGAC 
GGCGAGGGAA AGGGACCCTT TGCTAAATTT GAACTGTTTG TTTTGGACCC AGCCGGAGAC 
TGGTATTACC GTTGGTTGTT TGTCATTGCC ATGCCTGTTC TTTACAACTG GTGCCTGTTG 
GTGGCCAGAG CCTGCTTCAG TGATCTACAG AGAAACTATT TTGTGGTATG GCTGGTGCTG 
GACTACTTCT CAGACACTGT CTATATCGCA GACCTCATCA TTCGGCTGCG CACAGGCTTC 
CTAGAACAGG GGCTCTTGGT CAAAGATCCC AAGAAATTGC GAGACAACTA TATTCACACT 
TTGCAGTTCA AATTGGATGT GGCTTCTATC ATTCCCACTG ACCTTATCTA TTTTGCTGTG 
GGTATCCACA GCCCTGAGGT ACGCTTCAAC CGTCTATTAC ACTTTGCCCG TATGTTTGAG 
TTCTTTGACC GCACTGAGAC ACGCACCAGC TACCCCAACA TCTTCCGAAT CAGCAATCTG 
GTCCTTTACA TCTTGGTCAT CATCCACTGG AATGCTTGTA TTTATTATGT TATTTCTAAG 
TCCATTGGCT TTGGAGTTGA CACCTGGGTT TACCCCAACA TTACTGACCC TGAATATGGC 
TACCTGGCTA GAGAGTACAT TTACTGTCTT TACTGGTCCA CACTGACCCT CACCACCATT 
GGAGAGACAC CACCCCCTGT AAAGGATGAG GAGTACCTAT TTGTCATCTT TGACTTCTTG 
ATTGGTGTCC TCATCTTTGC CACTATTGTG GGAAATGTGG GCTCCATGAT CTCCAACATG 
AATGCCACAC GAGCAGAGTT CCAGGCCAAG ATTGATGCTG TCAAACACTA CATGCAGTTC 
CGAAAGGTCA GCAAAGACAT GGAAGCCAAG GTCATCAAAT GGTTTGACTA CTTGTGGACC 
AATAAGAAGA CAGTAGATGA ACGAGAAGTC CTCAAGAACC TGCCAGCAAA GCTCAGGGCT 
GAGATAGCCA TTAATGTTCA CTTGTCCACT CTGAAGAAAG TGCGCATATT CCAGGATTGT 
GAAGCTGGCC TACTGGTGGA ACTGGTACTG AAGCTTCGTC CTCAGGTCTT TAGTCCTGGA 
GATTATATTT GCCGTAAGGG GGACATTGGC AAGGAAATGT ACATCATCAA GGAGGGCAAG 
TTGGCAGTGG TAGCTGATGA TGGCGTGACT CAGTATGCCT TGCTCTCAGC TGGGAGCTGC 
TTTGGTGAGA TTAGTATCCT TAACATTAAG GGTAGCAAAA TGGGCAATCG ACGTACTGCT 
AATATCCGTA GCCTGGGCTA CTCAGATCTC TTCTGCTTGT CCAAGGACGA TCTTATGGAA 
GCTGTAACTG AGTATCCTGA TGCCAAGAAG GTCCTGGAGG AACGGGGTAG GGAGATCCTG 
ATGAAGGAAG GTCTACTGGA TGAGAATGAA GTGGCAGCTA GTATGGAGGT AGATGTTCAG 
GAGAAGCTGG AACAGTTGGA GACAAACATG GATACCTTGT ACACTCGCTT TGCCCGCCTG 
CTGGCTGAGT ACACTGGGGC CCAGCAGAAG CTCAAGCAAC GCATCACAGT GCTAGAGACC 
AAGATGAAAC AGAACCATGA GGATGATTAT CTATCAGATG GGATAAACAC TCCTGAGCCA 
ACTGCTGCTG AATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

'Smelling' the cerebrospinal fluid: olfactory signaling molecules are expressed in and mediate chemosensory signaling from the choroid plexus.
The FEBS journal283(9)1748-66(2016 05)
Gon?alves I,Hubbard PC,Tom?s J,Quintela T,Tavares G,Caria S,Barreiros D,Santos CR

Binding orientation and specificity of calmodulin to rat olfactory cyclic nucleotide-gated ion channel.
Journal of biomolecular structure & dynamics31(4)414-25(2013 Apr)
Irene D,Huang JW,Chung TY,Li FY,Tzen JT,Lin TH,Chyan CL

Differential regulation by cyclic nucleotides of the CNGA4 and CNGB1b subunits in olfactory cyclic nucleotide-gated channels.
Science signaling5(232)ra48(2012 Jul)
Nache V,Zimmer T,Wongsamitkul N,Schmauder R,Kusch J,Reinhardt L,B?nigk W,Seifert R,Biskup C,Schwede F,Benndorf K

Calcium signalling remodelling and disease.
Biochemical Society transactions40(2)297-309(2012 Apr)
Berridge MJ

Ca2+-activated Cl? currents are dispensable for olfaction.
Nature neuroscience14(6)763-9(2011 Jun)
Billig GM,P?l B,Fidzinski P,Jentsch TJ

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