Cnga2 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Cnga2
Entrez Gene ID	12789
Full Name	cyclic nucleotide gated channel alpha 2
Synonyms	CNG2,Cnca,Cncg4,OCNC1
General protein information	Preferred Names cyclic nucleotide gated channel alpha 2 Names cyclic nucleotide-gated olfactory channel CNG channel alpha-2 cyclic nucleotide gated channel 4 cyclic nucleotide-gated cation channel 2
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: X Map Location: X\|X A7.3
Summary	This gene encodes a transmembrane protein that is a subunit of the nucleotide-gated olfactory ion channel. Knock out of this gene affects development of the olfactory epithelium and olfactory bulb. [provided by RefSeq, May 2015].

mRNA and Protein(s)

mRNA	Protein	Name
NM_007724.3	NP_031750.2	cyclic nucleotide-gated olfactory channel
XM_006527761.1	XP_006527824.1	cyclic nucleotide-gated olfactory channel isoform X1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	CNGA2	XP_529195.2
Bos taurus (cattle)	CNGA2	NP_001001139.1
Danio rerio (zebrafish)	cnga5	NP_001038211.1
Rattus norvegicus (Norway rat)	Cnga2	NP_037060.1
Xenopus tropicalis (tropical clawed frog)	cnga2	XP_002939246.1
	LOC704486	XP_001092844.2
Homo sapiens (human)	CNGA2	NP_005131.1
Canis lupus familiaris (dog)	CNGA2	XP_005642014.1
Mus musculus (house mouse)	Cnga2	NP_031750.2
Gallus gallus (chicken)	CNGA2	XP_001234866.3

Gene Ontology
Bibliography

Related articles in PubMed

Hedgehog signaling regulates ciliary localization of mouse odorant receptors.
Maurya DK, Bohm S, Alenius M
Proceedings of the National Academy of Sciences of the United States of America114(44)E9386-E9394(2017 Oct)

Social Control of Hypothalamus-Mediated Male Aggression.
Yang T, Yang CF, Chizari MD, Maheswaranathan N, Burke KJ Jr, Borius M, Inoue S, Chiang MC, Bender KJ, Ganguli S, Shah NM
Neuron95(4)955-970.e4(2017 Aug)

A Sensor for Low Environmental Oxygen in the Mouse Main Olfactory Epithelium.
Bleymehl K, P?rez-G?mez A, Omura M, Moreno-P?rez A, Mac?as D, Bai Z, Johnson RS, Leinders-Zufall T, Zufall F, Mombaerts P
Neuron92(6)1196-1203(2016 Dec)

Cnga2 Knockout Mice Display Alzheimer's-Like Behavior Abnormities and Pathological Changes.
Xie AJ, Liu EJ, Huang HZ, Hu Y, Li K, Lu Y, Wang JZ, Zhu LQ
Molecular neurobiology53(7)4992-9(2016 Sep)

Formation of precise connections in the olfactory bulb occurs in the absence of odorant-evoked neuronal activity.
Lin DM, Wang F, Lowe G, Gold GH, Axel R, Ngai J, Brunet L
Neuron26(1)69-80(2000 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

In Cnga2 knock-out mice there was an overproduction of Amyloid beta protein, tau hyper-phosphorylation, and behavioral abnormalities.
Title: Cnga2 Knockout Mice Display Alzheimer's-Like Behavior Abnormities and Pathological Changes.

This study found that Cnga2 mice showed increased anxiety- and depressive-like behaviors than their wide type siblings.
Title: Anxiety- and depressive-like behaviors in olfactory deficient Cnga2 knockout mice.

Retinoic acid receptor and CNGA2 channel signaling are part of a regulatory feedback loop controlling axonal convergence and survival of olfactory sensory neurons.
Title: Retinoic acid receptor and CNGA2 channel signaling are part of a regulatory feedback loop controlling axonal convergence and survival of olfactory sensory neurons.

CNGA2 channels contribute to ATP-induced non-capacitative calcium influx in vascular endothelial cells. It is likely that ATP acts through P2Y(1)receptors and adenylyl cyclases to stimulate CNGA2.
Title: CNGA2 contributes to ATP-induced noncapacitative Ca2+ influx in vascular endothelial cells.

Mediates epinephrine-induced endothelial calcium influx and subsequent vascular dilation.
Title: Epinephrine-induced Ca2+ influx in vascular endothelial cells is mediated by CNGA2 channels.

The following Cnga2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cnga2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu19184	NM_007724.3 Latest version!	Mus musculus cyclic nucleotide gated channel alpha 2 (Cnga2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$307.30 $439.00
OMu19184	XM_006527761.1 Latest version!	Mus musculus cyclic nucleotide gated channel alpha 2 (Cnga2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$307.30 $439.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Cnga2 ( NM_007724.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_031750.2 Mus musculus cyclic nucleotide gated channel alpha 2 (Cnga2), mRNA.

Price & Availability↑

CloneID	OMu19184
Clone ID Related Accession (Same CDS sequence)	NM_007724.3 , XM_006527761.1
Accession Version	NM_007724.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1995bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-28
Organism	Mus musculus(house mouse)
Product	cyclic nucleotide-gated olfactory channel
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK132574.1 and BC048775.1. On May 7, 2015 this sequence version replaced NM_007724.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC048775.1, AK132574.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849381, SAMN01164131 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGATGACCG AAAAATCCAA CGGTGTGAAG AGCTCTCCAG CTAATAACCA TAACCATCAT 
CCTCCTCCTT CTATCAAGGC CAATGGCAAA GATGACCACA GGGCAGGTAG CAGACCACAG 
TCTGTGGCAG CTGATGATGA CACTTCCTCA GAACTGCAAA GGTTGGCAGA GATGGATACT 
CCACGCAGGG GAAGGGGTGG CTTCCGAAGG ATTGTCCGCC TGGTGGGGAT CATCAGAGAC 
TGGGCCAACA AAAATTTCCG TGAGGAGGAA CCAAGACCTG ACTCCTTCCT AGAGCGTTTC 
CGTGGGCCTG AGCTCCAGAC TGTGACAACC CATCAGGGGG ATGGCAAAGG CGACAAGGAC 
GGCGAGGGAA AGGGCACCAA AAAGAAATTT GAACTGTTTG TTTTGGACCC AGCTGGAGAC 
TGGTATTACC GTTGGTTGTT TGTCATTGCC ATGCCTGTTC TTTACAACTG GTGTCTGTTG 
GTAGCCAGAG CCTGCTTCAG TGATCTACAG AGAAACTATT TTGTGGTATG GCTGGTGCTG 
GATTACTTCT CAGACACTGT TTATATTGCA GACCTCATCA TTCGGCTGCG CACAGGCTTC 
CTAGAACAAG GGCTCCTGGT CAAAGACCCC AAGAAATTGC GAGACAACTA TATCCACACT 
TTGCAGTTCA AATTGGATGT GGCTTCTATC ATCCCCACTG ACCTCATTTA TTTTGCTGTG 
GGTATCCACA GCCCTGAGGT ACGCTTTAAT CGTCTGTTAC ACTTTGCCCG TATGTTTGAG 
TTCTTTGACC GCACTGAGAC ACGTACAAGC TACCCCAACA TCTTCCGAAT CAGCAACCTG 
GTCCTCTACA TCTTGGTCAT CATCCACTGG AATGCTTGTA TTTACTATGC TATCTCTAAG 
TCCATTGGCT TTGGGGTTGA CACCTGGGTT TACCCCAACA TTACTGACCC TGAATATGGC 
TACCTGGCTA GGGAGTACAT TTACTGCCTT TACTGGTCCA CACTGACCCT CACCACCATT 
GGAGAGACAC CACCCCCTGT AAAGGATGAG GAGTACCTAT TTGTCATCTT TGACTTCCTG 
ATTGGTGTCC TCATCTTTGC CACTATTGTG GGAAATGTGG GCTCCATGAT CTCCAACATG 
AATGCCACAC GAGCAGAGTT CCAGGCCAAG ATTGATGCTG TCAAACACTA CATGCAGTTC 
CGAAAGGTCA GTAAAGACAT GGAAGCCAAG GTCATCAAAT GGTTTGACTA CTTGTGGACC 
AATAAGAAGA CAGTAGATGA ACGAGAAGTC CTAAAGAACC TGCCTGCAAA GCTTAGGGCA 
GAGATAGCCA TTAATGTTCA TTTGTCCACT CTGAAGAAAG TGCGCATATT CCAGGATTGT 
GAAGCTGGCC TGCTGGTGGA ACTGGTACTG AAGCTTCGTC CTCAGGTCTT TAGTCCTGGA 
GATTATATTT GCCGTAAGGG GGACATTGGC AAGGAAATGT ACATCATCAA GGAGGGCAAA 
TTGGCAGTGG TAGCTGATGA TGGTGTGACT CAGTATGCCT TGCTGTCAGC TGGGAGCTGC 
TTTGGTGAGA TTAGTATCCT TAACATTAAG GGTAGCAAAA TGGGCAATCG GCGCACTGCC 
AATATCCGTA GTCTGGGCTA CTCAGATCTC TTCTGCTTGT CCAAGGATGA TCTTATGGAA 
GCTGTGACTG AGTATCCTGA TGCCAAGAAA GTCCTGGAAG AACGGGGTAG GGAGATCCTG 
ATGAAGGAAG GTCTACTGGA TGAGAATGAA GTGGCAGCTA GTATGGAGGT AGATGTTCAG 
GAGAAGCTGG AGCAGCTGGA GACAAACATG GAGACCTTGT ACACTCGTTT TGCCCGCCTG 
CTGGCTGAGT ACACTGGAGC CCAGCAGAAG CTCAAACAGC GCATCACAGT GCTGGAGACC 
AAGATGAAAC AGAACCATGA GGATGATTAC CTATCAGATG GGATAAACAC CCCTGAGCCA 
GCTGTTGCTG AATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_031750.2
CDS	367..2361
Translation	MMTEKSNGVKSSPANNHNHHPPPSIKANGKDDHRAGSRPQSVAADDDTSSELQRLAEMDTPRRGRGGFRRIVRLVGIIRDWANKNFREEEPRPDSFLERFRGPELQTVTTHQGDGKGDKDGEGKGTKKKFELFVLDPAGDWYYRWLFVIAMPVLYNWCLLVARACFSDLQRNYFVVWLVLDYFSDTVYIADLIIRLRTGFLEQGLLVKDPKKLRDNYIHTLQFKLDVASIIPTDLIYFAVGIHSPEVRFNRLLHFARMFEFFDRTETRTSYPNIFRISNLVLYILVIIHWNACIYYAISKSIGFGVDTWVYPNITDPEYGYLAREYIYCLYWSTLTLTTIGETPPPVKDEEYLFVIFDFLIGVLIFATIVGNVGSMISNMNATRAEFQAKIDAVKHYMQFRKVSKDMEAKVIKWFDYLWTNKKTVDEREVLKNLPAKLRAEIAINVHLSTLKKVRIFQDCEAGLLVELVLKLRPQVFSPGDYICRKGDIGKEMYIIKEGKLAVVADDGVTQYALLSAGSCFGEISILNIKGSKMGNRRTANIRSLGYSDLFCLSKDDLMEAVTEYPDAKKVLEERGREILMKEGLLDENEVAASMEVDVQEKLEQLETNMETLYTRFARLLAEYTGAQQKLKQRITVLETKMKQNHEDDYLSDGINTPEPAVAE

Target ORF information:

RefSeq Version	NM_007724.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus cyclic nucleotide gated channel alpha 2 (Cnga2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_007724.3

ORF Insert Sequence:

ATGATGACCG AAAAATCCAA CGGTGTGAAG AGCTCTCCAG CTAATAACCA TAACCATCAT 
CCTCCTCCTT CTATCAAGGC CAATGGCAAA GATGACCACA GGGCAGGTAG CAGACCACAG 
TCTGTGGCAG CTGATGATGA CACTTCCTCA GAACTGCAAA GGTTGGCAGA GATGGATACT 
CCACGCAGGG GAAGGGGTGG CTTCCGAAGG ATTGTCCGCC TGGTGGGGAT CATCAGAGAC 
TGGGCCAACA AAAATTTCCG TGAGGAGGAA CCAAGACCTG ACTCCTTCCT AGAGCGTTTC 
CGTGGGCCTG AGCTCCAGAC TGTGACAACC CATCAGGGGG ATGGCAAAGG CGACAAGGAC 
GGCGAGGGAA AGGGCACCAA AAAGAAATTT GAACTGTTTG TTTTGGACCC AGCTGGAGAC 
TGGTATTACC GTTGGTTGTT TGTCATTGCC ATGCCTGTTC TTTACAACTG GTGTCTGTTG 
GTAGCCAGAG CCTGCTTCAG TGATCTACAG AGAAACTATT TTGTGGTATG GCTGGTGCTG 
GATTACTTCT CAGACACTGT TTATATTGCA GACCTCATCA TTCGGCTGCG CACAGGCTTC 
CTAGAACAAG GGCTCCTGGT CAAAGACCCC AAGAAATTGC GAGACAACTA TATCCACACT 
TTGCAGTTCA AATTGGATGT GGCTTCTATC ATCCCCACTG ACCTCATTTA TTTTGCTGTG 
GGTATCCACA GCCCTGAGGT ACGCTTTAAT CGTCTGTTAC ACTTTGCCCG TATGTTTGAG 
TTCTTTGACC GCACTGAGAC ACGTACAAGC TACCCCAACA TCTTCCGAAT CAGCAACCTG 
GTCCTCTACA TCTTGGTCAT CATCCACTGG AATGCTTGTA TTTACTATGC TATCTCTAAG 
TCCATTGGCT TTGGGGTTGA CACCTGGGTT TACCCCAACA TTACTGACCC TGAATATGGC 
TACCTGGCTA GGGAGTACAT TTACTGCCTT TACTGGTCCA CACTGACCCT CACCACCATT 
GGAGAGACAC CACCCCCTGT AAAGGATGAG GAGTACCTAT TTGTCATCTT TGACTTCCTG 
ATTGGTGTCC TCATCTTTGC CACTATTGTG GGAAATGTGG GCTCCATGAT CTCCAACATG 
AATGCCACAC GAGCAGAGTT CCAGGCCAAG ATTGATGCTG TCAAACACTA CATGCAGTTC 
CGAAAGGTCA GTAAAGACAT GGAAGCCAAG GTCATCAAAT GGTTTGACTA CTTGTGGACC 
AATAAGAAGA CAGTAGATGA ACGAGAAGTC CTAAAGAACC TGCCTGCAAA GCTTAGGGCA 
GAGATAGCCA TTAATGTTCA TTTGTCCACT CTGAAGAAAG TGCGCATATT CCAGGATTGT 
GAAGCTGGCC TGCTGGTGGA ACTGGTACTG AAGCTTCGTC CTCAGGTCTT TAGTCCTGGA 
GATTATATTT GCCGTAAGGG GGACATTGGC AAGGAAATGT ACATCATCAA GGAGGGCAAA 
TTGGCAGTGG TAGCTGATGA TGGTGTGACT CAGTATGCCT TGCTGTCAGC TGGGAGCTGC 
TTTGGTGAGA TTAGTATCCT TAACATTAAG GGTAGCAAAA TGGGCAATCG GCGCACTGCC 
AATATCCGTA GTCTGGGCTA CTCAGATCTC TTCTGCTTGT CCAAGGATGA TCTTATGGAA 
GCTGTGACTG AGTATCCTGA TGCCAAGAAA GTCCTGGAAG AACGGGGTAG GGAGATCCTG 
ATGAAGGAAG GTCTACTGGA TGAGAATGAA GTGGCAGCTA GTATGGAGGT AGATGTTCAG 
GAGAAGCTGG AGCAGCTGGA GACAAACATG GAGACCTTGT ACACTCGTTT TGCCCGCCTG 
CTGGCTGAGT ACACTGGAGC CCAGCAGAAG CTCAAACAGC GCATCACAGT GCTGGAGACC 
AAGATGAAAC AGAACCATGA GGATGATTAC CTATCAGATG GGATAAACAC CCCTGAGCCA 
GCTGTTGCTG AATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cnga2 ( XM_006527761.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006527824.1 Mus musculus cyclic nucleotide gated channel alpha 2 (Cnga2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu19184
Clone ID Related Accession (Same CDS sequence)	NM_007724.3 , XM_006527761.1
Accession Version	XM_006527761.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1995bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	cyclic nucleotide-gated olfactory channel isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000086.7) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATGACCG AAAAATCCAA CGGTGTGAAG AGCTCTCCAG CTAATAACCA TAACCATCAT 
CCTCCTCCTT CTATCAAGGC CAATGGCAAA GATGACCACA GGGCAGGTAG CAGACCACAG 
TCTGTGGCAG CTGATGATGA CACTTCCTCA GAACTGCAAA GGTTGGCAGA GATGGATACT 
CCACGCAGGG GAAGGGGTGG CTTCCGAAGG ATTGTCCGCC TGGTGGGGAT CATCAGAGAC 
TGGGCCAACA AAAATTTCCG TGAGGAGGAA CCAAGACCTG ACTCCTTCCT AGAGCGTTTC 
CGTGGGCCTG AGCTCCAGAC TGTGACAACC CATCAGGGGG ATGGCAAAGG CGACAAGGAC 
GGCGAGGGAA AGGGCACCAA AAAGAAATTT GAACTGTTTG TTTTGGACCC AGCTGGAGAC 
TGGTATTACC GTTGGTTGTT TGTCATTGCC ATGCCTGTTC TTTACAACTG GTGTCTGTTG 
GTAGCCAGAG CCTGCTTCAG TGATCTACAG AGAAACTATT TTGTGGTATG GCTGGTGCTG 
GATTACTTCT CAGACACTGT TTATATTGCA GACCTCATCA TTCGGCTGCG CACAGGCTTC 
CTAGAACAAG GGCTCCTGGT CAAAGACCCC AAGAAATTGC GAGACAACTA TATCCACACT 
TTGCAGTTCA AATTGGATGT GGCTTCTATC ATCCCCACTG ACCTCATTTA TTTTGCTGTG 
GGTATCCACA GCCCTGAGGT ACGCTTTAAT CGTCTGTTAC ACTTTGCCCG TATGTTTGAG 
TTCTTTGACC GCACTGAGAC ACGTACAAGC TACCCCAACA TCTTCCGAAT CAGCAACCTG 
GTCCTCTACA TCTTGGTCAT CATCCACTGG AATGCTTGTA TTTACTATGC TATCTCTAAG 
TCCATTGGCT TTGGGGTTGA CACCTGGGTT TACCCCAACA TTACTGACCC TGAATATGGC 
TACCTGGCTA GGGAGTACAT TTACTGCCTT TACTGGTCCA CACTGACCCT CACCACCATT 
GGAGAGACAC CACCCCCTGT AAAGGATGAG GAGTACCTAT TTGTCATCTT TGACTTCCTG 
ATTGGTGTCC TCATCTTTGC CACTATTGTG GGAAATGTGG GCTCCATGAT CTCCAACATG 
AATGCCACAC GAGCAGAGTT CCAGGCCAAG ATTGATGCTG TCAAACACTA CATGCAGTTC 
CGAAAGGTCA GTAAAGACAT GGAAGCCAAG GTCATCAAAT GGTTTGACTA CTTGTGGACC 
AATAAGAAGA CAGTAGATGA ACGAGAAGTC CTAAAGAACC TGCCTGCAAA GCTTAGGGCA 
GAGATAGCCA TTAATGTTCA TTTGTCCACT CTGAAGAAAG TGCGCATATT CCAGGATTGT 
GAAGCTGGCC TGCTGGTGGA ACTGGTACTG AAGCTTCGTC CTCAGGTCTT TAGTCCTGGA 
GATTATATTT GCCGTAAGGG GGACATTGGC AAGGAAATGT ACATCATCAA GGAGGGCAAA 
TTGGCAGTGG TAGCTGATGA TGGTGTGACT CAGTATGCCT TGCTGTCAGC TGGGAGCTGC 
TTTGGTGAGA TTAGTATCCT TAACATTAAG GGTAGCAAAA TGGGCAATCG GCGCACTGCC 
AATATCCGTA GTCTGGGCTA CTCAGATCTC TTCTGCTTGT CCAAGGATGA TCTTATGGAA 
GCTGTGACTG AGTATCCTGA TGCCAAGAAA GTCCTGGAAG AACGGGGTAG GGAGATCCTG 
ATGAAGGAAG GTCTACTGGA TGAGAATGAA GTGGCAGCTA GTATGGAGGT AGATGTTCAG 
GAGAAGCTGG AGCAGCTGGA GACAAACATG GAGACCTTGT ACACTCGTTT TGCCCGCCTG 
CTGGCTGAGT ACACTGGAGC CCAGCAGAAG CTCAAACAGC GCATCACAGT GCTGGAGACC 
AAGATGAAAC AGAACCATGA GGATGATTAC CTATCAGATG GGATAAACAC CCCTGAGCCA 
GCTGTTGCTG AATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006527824.1
CDS	207..2201
Translation	MMTEKSNGVKSSPANNHNHHPPPSIKANGKDDHRAGSRPQSVAADDDTSSELQRLAEMDTPRRGRGGFRRIVRLVGIIRDWANKNFREEEPRPDSFLERFRGPELQTVTTHQGDGKGDKDGEGKGTKKKFELFVLDPAGDWYYRWLFVIAMPVLYNWCLLVARACFSDLQRNYFVVWLVLDYFSDTVYIADLIIRLRTGFLEQGLLVKDPKKLRDNYIHTLQFKLDVASIIPTDLIYFAVGIHSPEVRFNRLLHFARMFEFFDRTETRTSYPNIFRISNLVLYILVIIHWNACIYYAISKSIGFGVDTWVYPNITDPEYGYLAREYIYCLYWSTLTLTTIGETPPPVKDEEYLFVIFDFLIGVLIFATIVGNVGSMISNMNATRAEFQAKIDAVKHYMQFRKVSKDMEAKVIKWFDYLWTNKKTVDEREVLKNLPAKLRAEIAINVHLSTLKKVRIFQDCEAGLLVELVLKLRPQVFSPGDYICRKGDIGKEMYIIKEGKLAVVADDGVTQYALLSAGSCFGEISILNIKGSKMGNRRTANIRSLGYSDLFCLSKDDLMEAVTEYPDAKKVLEERGREILMKEGLLDENEVAASMEVDVQEKLEQLETNMETLYTRFARLLAEYTGAQQKLKQRITVLETKMKQNHEDDYLSDGINTPEPAVAE

Target ORF information:

RefSeq Version	XM_006527761.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus cyclic nucleotide gated channel alpha 2 (Cnga2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006527761.1

ORF Insert Sequence:

ATGATGACCG AAAAATCCAA CGGTGTGAAG AGCTCTCCAG CTAATAACCA TAACCATCAT 
CCTCCTCCTT CTATCAAGGC CAATGGCAAA GATGACCACA GGGCAGGTAG CAGACCACAG 
TCTGTGGCAG CTGATGATGA CACTTCCTCA GAACTGCAAA GGTTGGCAGA GATGGATACT 
CCACGCAGGG GAAGGGGTGG CTTCCGAAGG ATTGTCCGCC TGGTGGGGAT CATCAGAGAC 
TGGGCCAACA AAAATTTCCG TGAGGAGGAA CCAAGACCTG ACTCCTTCCT AGAGCGTTTC 
CGTGGGCCTG AGCTCCAGAC TGTGACAACC CATCAGGGGG ATGGCAAAGG CGACAAGGAC 
GGCGAGGGAA AGGGCACCAA AAAGAAATTT GAACTGTTTG TTTTGGACCC AGCTGGAGAC 
TGGTATTACC GTTGGTTGTT TGTCATTGCC ATGCCTGTTC TTTACAACTG GTGTCTGTTG 
GTAGCCAGAG CCTGCTTCAG TGATCTACAG AGAAACTATT TTGTGGTATG GCTGGTGCTG 
GATTACTTCT CAGACACTGT TTATATTGCA GACCTCATCA TTCGGCTGCG CACAGGCTTC 
CTAGAACAAG GGCTCCTGGT CAAAGACCCC AAGAAATTGC GAGACAACTA TATCCACACT 
TTGCAGTTCA AATTGGATGT GGCTTCTATC ATCCCCACTG ACCTCATTTA TTTTGCTGTG 
GGTATCCACA GCCCTGAGGT ACGCTTTAAT CGTCTGTTAC ACTTTGCCCG TATGTTTGAG 
TTCTTTGACC GCACTGAGAC ACGTACAAGC TACCCCAACA TCTTCCGAAT CAGCAACCTG 
GTCCTCTACA TCTTGGTCAT CATCCACTGG AATGCTTGTA TTTACTATGC TATCTCTAAG 
TCCATTGGCT TTGGGGTTGA CACCTGGGTT TACCCCAACA TTACTGACCC TGAATATGGC 
TACCTGGCTA GGGAGTACAT TTACTGCCTT TACTGGTCCA CACTGACCCT CACCACCATT 
GGAGAGACAC CACCCCCTGT AAAGGATGAG GAGTACCTAT TTGTCATCTT TGACTTCCTG 
ATTGGTGTCC TCATCTTTGC CACTATTGTG GGAAATGTGG GCTCCATGAT CTCCAACATG 
AATGCCACAC GAGCAGAGTT CCAGGCCAAG ATTGATGCTG TCAAACACTA CATGCAGTTC 
CGAAAGGTCA GTAAAGACAT GGAAGCCAAG GTCATCAAAT GGTTTGACTA CTTGTGGACC 
AATAAGAAGA CAGTAGATGA ACGAGAAGTC CTAAAGAACC TGCCTGCAAA GCTTAGGGCA 
GAGATAGCCA TTAATGTTCA TTTGTCCACT CTGAAGAAAG TGCGCATATT CCAGGATTGT 
GAAGCTGGCC TGCTGGTGGA ACTGGTACTG AAGCTTCGTC CTCAGGTCTT TAGTCCTGGA 
GATTATATTT GCCGTAAGGG GGACATTGGC AAGGAAATGT ACATCATCAA GGAGGGCAAA 
TTGGCAGTGG TAGCTGATGA TGGTGTGACT CAGTATGCCT TGCTGTCAGC TGGGAGCTGC 
TTTGGTGAGA TTAGTATCCT TAACATTAAG GGTAGCAAAA TGGGCAATCG GCGCACTGCC 
AATATCCGTA GTCTGGGCTA CTCAGATCTC TTCTGCTTGT CCAAGGATGA TCTTATGGAA 
GCTGTGACTG AGTATCCTGA TGCCAAGAAA GTCCTGGAAG AACGGGGTAG GGAGATCCTG 
ATGAAGGAAG GTCTACTGGA TGAGAATGAA GTGGCAGCTA GTATGGAGGT AGATGTTCAG 
GAGAAGCTGG AGCAGCTGGA GACAAACATG GAGACCTTGT ACACTCGTTT TGCCCGCCTG 
CTGGCTGAGT ACACTGGAGC CCAGCAGAAG CTCAAACAGC GCATCACAGT GCTGGAGACC 
AAGATGAAAC AGAACCATGA GGATGATTAC CTATCAGATG GGATAAACAC CCCTGAGCCA 
GCTGTTGCTG AATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Hedgehog signaling regulates ciliary localization of mouse odorant receptors.
Proceedings of the National Academy of Sciences of the United States of America114(44)E9386-E9394(2017 Oct)
Maurya DK,Bohm S,Alenius M

Social Control of Hypothalamus-Mediated Male Aggression.
Neuron95(4)955-970.e4(2017 Aug)
Yang T,Yang CF,Chizari MD,Maheswaranathan N,Burke KJ Jr,Borius M,Inoue S,Chiang MC,Bender KJ,Ganguli S,Shah NM

A Sensor for Low Environmental Oxygen in the Mouse Main Olfactory Epithelium.
Neuron92(6)1196-1203(2016 Dec)
Bleymehl K,P?rez-G?mez A,Omura M,Moreno-P?rez A,Mac?as D,Bai Z,Johnson RS,Leinders-Zufall T,Zufall F,Mombaerts P

Cnga2 Knockout Mice Display Alzheimer's-Like Behavior Abnormities and Pathological Changes.
Molecular neurobiology53(7)4992-9(2016 Sep)
Xie AJ,Liu EJ,Huang HZ,Hu Y,Li K,Lu Y,Wang JZ,Zhu LQ

Formation of precise connections in the olfactory bulb occurs in the absence of odorant-evoked neuronal activity.
Neuron26(1)69-80(2000 Apr)
Lin DM,Wang F,Lowe G,Gold GH,Axel R,Ngai J,Brunet L

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Cnga2 cDNA ORF clone, Mus musculus(house mouse)

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ORF Insert Sequence:

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