Adora3 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Adora3
Entrez Gene ID	25370
Full Name	adenosine A3 receptor
Synonyms	Tgpcr1
General protein information	Preferred Names adenosine A3 receptor Names adenosine receptor A3
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 2 Map Location: 2q34
Summary	may play a role in remodelling after myocardial cell injury; may be involved in male reproduction [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_006233067.3	XP_006233129.1	adenosine receptor A3 isoform X1
NM_012896.3	NP_037028.2	adenosine receptor A3 isoform b
NM_001302755.1	NP_001289684.1	adenosine receptor A3 isoform a

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Adora3	NP_037028.2
Rattus norvegicus (Norway rat)	LOC100911796	XP_003749422.1

Gene Ontology
Bibliography

Related articles in PubMed

Genome-wide RNAi screening identifies TMIGD3 isoform1 as a suppressor of NF-?B and osteosarcoma progression.
Iyer SV, Ranjan A, Elias HK, Parrales A, Sasaki H, Roy BC, Umar S, Tawfik OW, Iwakuma T
Nature communications713561(2016 Nov)

Adenosine A3 receptor activation is neuroprotective against retinal neurodegeneration.
Galvao J, Elvas F, Martins T, Cordeiro MF, Ambr?sio AF, Santiago AR
Experimental eye research14065-74(2015 Nov)

Evidence for A1 and A 3 receptors mediating adenosine-induced intracellular calcium release in the dorsal root ganglion neurons by using confocal microscopy imaging.
Zheng L, Chen J, Huang Y, Wang Y, Yang H, Zhang Y, Xie S
Lasers in medical science29(3)1209-15(2014 May)

A3 Adenosine receptors mediate oligodendrocyte death and ischemic damage to optic nerve.
Gonz?lez-Fern?ndez E, S?nchez-G?mez MV, P?rez-Samart?n A, Arellano RO, Matute C
Glia62(2)199-216(2014 Feb)

Oxygen/glucose deprivation induces a reduction in synaptic AMPA receptors on hippocampal CA3 neurons mediated by mGluR1 and adenosine A3 receptors.
Dennis SH, Jaafari N, Cimarosti H, Hanley JG, Henley JM, Mellor JR
The Journal of neuroscience : the official journal of the Society for Neuroscience31(33)11941-52(2011 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Activation of A3R may have great potential in the management of retinal neurodegenerative diseases.
Title: Adenosine A3 receptor activation is neuroprotective against retinal neurodegeneration.

A1R and A3R, were identified to be involved in the adenosine-induced Ca(2+) release from intracellular stores in neurons.
Title: Evidence for A1 and A 3 receptors mediating adenosine-induced intracellular calcium release in the dorsal root ganglion neurons by using confocal microscopy imaging.

adenosine may trigger oligodendrocyte death via activation of A3 receptors
Title: A3 Adenosine receptors mediate oligodendrocyte death and ischemic damage to optic nerve.

[review] Activation of both Adora1 and Adora3 receptors prior to ischemia has been shown in multiple experimental models to reduce ischemia/reperfusion-induced cardiac injury.
Title: Adenosine receptor-mediated cardioprotection: are all 4 subtypes required or redundant?

Oxygen/glucose deprivation induces a reduction in synaptic AMPA receptors mediated by adenosine A3 and mGluR1 receptors.
Title: Oxygen/glucose deprivation induces a reduction in synaptic AMPA receptors on hippocampal CA3 neurons mediated by mGluR1 and adenosine A3 receptors.

The following Adora3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Adora3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa01242	NM_012896.3 Latest version!	Rattus norvegicus adenosine A3 receptor (Adora3), transcript variant A3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
ORa25131	XM_006233067.3 Latest version!	Rattus norvegicus adenosine A3 receptor (Adora3), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
ORa25130	NM_001302755.1 Latest version!	Rattus norvegicus adenosine A3 receptor (Adora3), transcript variant A3i, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Adora3 ( NM_012896.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_037028.2 Rattus norvegicus adenosine A3 receptor (Adora3), transcript variant A3, mRNA.

Price & Availability↑

CloneID	ORa01242
Clone ID Related Accession (Same CDS sequence)	NM_012896.3
Accession Version	NM_012896.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 963bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-24
Organism	Rattus norvegicus(Norway rat)
Product	adenosine receptor A3 isoform b
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AABR07012777.1. On Nov 11, 2014 this sequence version replaced NM_012896.2. Transcript Variant: This variant (A3) uses an alternate in-frame splice site in the 3' terminal exon, compared to variant A3i, resulting in an isoform (b) that is shorter than isoform a. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: X59249.1, DQ075463.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMEA2689594 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAAGCCA ACAATACCAC GACGAGTGCC TTGTGGTTGC AAATCACCTA CATCACCATG 
GAGGCTGCCA TTGGTCTCTG TGCTGTAGTG GGCAACATGC TGGTCATCTG GGTGGTCAAG 
CTGAACCGCA CTCTGAGGAC CACCACCTTC TATTTCATCG TCTCCCTAGC ACTGGCTGAC 
ATTGCTGTTG GGGTGCTGGT CATACCCTTG GCCATTGCCG TCAGCCTGGA GGTCCAGATG 
CACTTCTATG CCTGCCTTTT CATGTCCTGT GTGCTTCTGG TCTTCACCCA CGCTTCCATC 
ATGTCCTTGC TGGCCATTGC TGTAGACCGA TACCTGCGAG TCAAGCTGAC AGTCAGATAT 
AGAACGGTTA CCACTCAAAG AAGAATATGG CTATTCCTGG GCCTCTGCTG GCTAGTGTCC 
TTTCTGGTGG GACTGACCCC CATGTTTGGC TGGAATAGAA AAGTGACCTT AGAGCTCTCT 
CAAAACAGCT CCACCCTCTC ATGCCACTTC CGTTCCGTGG TCGGCTTGGA TTACATGGTC 
TTCTTCAGCT TCATCACCTG GATCCTCATC CCCCTGGTTG TCATGTGCAT CATCTATCTG 
GACATCTTCT ACATCATCCG AAACAAACTC AGTCAAAATC TGACTGGCTT CAGAGAGACG 
CGTGCATTTT ACGGTCGGGA GTTCAAGACC GCTAAGTCCC TGTTTCTGGT TCTCTTCTTG 
TTTGCCTTGT GCTGGCTGCC TTTGTCCATC ATCAATTTTG TTTCCTACTT TAATGTGAAG 
ATACCAGAGA TTGCAATGTG CCTGGGCATC CTGTTGTCCC ATGCGAACTC CATGATGAAC 
CCTATTGTCT ACGCCTGCAA AATAAAAAAG TTCAAAGAAA CCTACTTTGT GATCCTCAGA 
GCTTGCAGGC TCTGTCAGAC CTCGGATTCT TTGGACTCAA ACCTTGAACA GACTACTGAG 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_037028.2
CDS	316..1278
Translation	MKANNTTTSALWLQITYITMEAAIGLCAVVGNMLVIWVVKLNRTLRTTTFYFIVSLALADIAVGVLVIPLAIAVSLEVQMHFYACLFMSCVLLVFTHASIMSLLAIAVDRYLRVKLTVRYRTVTTQRRIWLFLGLCWLVSFLVGLTPMFGWNRKVTLELSQNSSTLSCHFRSVVGLDYMVFFSFITWILIPLVVMCIIYLDIFYIIRNKLSQNLTGFRETRAFYGREFKTAKSLFLVLFLFALCWLPLSIINFVSYFNVKIPEIAMCLGILLSHANSMMNPIVYACKIKKFKETYFVILRACRLCQTSDSLDSNLEQTTE

Target ORF information:

RefSeq Version	NM_012896.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus adenosine A3 receptor (Adora3), transcript variant A3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_012896.3

ORF Insert Sequence:

ATGAAAGCCA ACAATACCAC GACGAGTGCC TTGTGGTTGC AAATCACCTA CATCACCATG 
GAGGCTGCCA TTGGTCTCTG TGCTGTAGTG GGCAACATGC TGGTCATCTG GGTGGTCAAG 
CTGAACCGCA CTCTGAGGAC CACCACCTTC TATTTCATCG TCTCCCTAGC ACTGGCTGAC 
ATTGCTGTTG GGGTGCTGGT CATACCCTTG GCCATTGCCG TCAGCCTGGA GGTCCAGATG 
CACTTCTATG CCTGCCTTTT CATGTCCTGT GTGCTTCTGG TCTTCACCCA CGCTTCCATC 
ATGTCCTTGC TGGCCATTGC TGTAGACCGA TACCTGCGAG TCAAGCTGAC AGTCAGATAT 
AGAACGGTTA CCACTCAAAG AAGAATATGG CTATTCCTGG GCCTCTGCTG GCTAGTGTCC 
TTTCTGGTGG GACTGACCCC CATGTTTGGC TGGAATAGAA AAGTGACCTT AGAGCTCTCT 
CAAAACAGCT CCACCCTCTC ATGCCACTTC CGTTCCGTGG TCGGCTTGGA TTACATGGTC 
TTCTTCAGCT TCATCACCTG GATCCTCATC CCCCTGGTTG TCATGTGCAT CATCTATCTG 
GACATCTTCT ACATCATCCG AAACAAACTC AGTCAAAATC TGACTGGCTT CAGAGAGACG 
CGTGCATTTT ACGGTCGGGA GTTCAAGACC GCTAAGTCCC TGTTTCTGGT TCTCTTCTTG 
TTTGCCTTGT GCTGGCTGCC TTTGTCCATC ATCAATTTTG TTTCCTACTT TAATGTGAAG 
ATACCAGAGA TTGCAATGTG CCTGGGCATC CTGTTGTCCC ATGCGAACTC CATGATGAAC 
CCTATTGTCT ACGCCTGCAA AATAAAAAAG TTCAAAGAAA CCTACTTTGT GATCCTCAGA 
GCTTGCAGGC TCTGTCAGAC CTCGGATTCT TTGGACTCAA ACCTTGAACA GACTACTGAG 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Adora3 ( XM_006233067.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006233129.1 Rattus norvegicus adenosine A3 receptor (Adora3), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa25131
Clone ID Related Accession (Same CDS sequence)	XM_006233067.3
Accession Version	XM_006233067.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 522bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	adenosine receptor A3 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005101.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006233067.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTTTGGCT GGAATAGAAA AGTGACCTTA GAGCTCTCTC AAAACAGCTC CACCCTCTCA 
TGCCACTTCC GTTCCGTGGT CGGCTTGGAT TACATGGTCT TCTTCAGCTT CATCACCTGG 
ATCCTCATCC CCCTGGTTGT CATGTGCATC ATCTATCTGG ACATCTTCTA CATCATCCGA 
AACAAACTCA GTCAAAATCT GACTGGCTTC AGAGAGACGC GTGCATTTTA CGGTCGGGAG 
TTCAAGACCG CTAAGTCCCT GTTTCTGGTT CTCTTCTTGT TTGCCTTGTG CTGGCTGCCT 
TTGTCCATCA TCAATTTTGT TTCCTACTTT AATGTGAAGA TACCAGAGAT TGCAATGTGC 
CTGGGCATCC TGTTGTCCCA TGCGAACTCC ATGATGAACC CTATTGTCTA CGCCTGCAAA 
ATAAAAAAGT TCAAAGAAAC CTACTTTGTG ATCCTCAGAG CTTGCAGGCT CTGTCAGACC 
TCGGATTCTT TGGACTCAAA CCTTGAACAG ACTACTGAGT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006233129.1
CDS	847..1368
Translation	MFGWNRKVTLELSQNSSTLSCHFRSVVGLDYMVFFSFITWILIPLVVMCIIYLDIFYIIRNKLSQNLTGFRETRAFYGREFKTAKSLFLVLFLFALCWLPLSIINFVSYFNVKIPEIAMCLGILLSHANSMMNPIVYACKIKKFKETYFVILRACRLCQTSDSLDSNLEQTTE

Target ORF information:

RefSeq Version	XM_006233067.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus adenosine A3 receptor (Adora3), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006233067.3

ORF Insert Sequence:

ATGTTTGGCT GGAATAGAAA AGTGACCTTA GAGCTCTCTC AAAACAGCTC CACCCTCTCA 
TGCCACTTCC GTTCCGTGGT CGGCTTGGAT TACATGGTCT TCTTCAGCTT CATCACCTGG 
ATCCTCATCC CCCTGGTTGT CATGTGCATC ATCTATCTGG ACATCTTCTA CATCATCCGA 
AACAAACTCA GTCAAAATCT GACTGGCTTC AGAGAGACGC GTGCATTTTA CGGTCGGGAG 
TTCAAGACCG CTAAGTCCCT GTTTCTGGTT CTCTTCTTGT TTGCCTTGTG CTGGCTGCCT 
TTGTCCATCA TCAATTTTGT TTCCTACTTT AATGTGAAGA TACCAGAGAT TGCAATGTGC 
CTGGGCATCC TGTTGTCCCA TGCGAACTCC ATGATGAACC CTATTGTCTA CGCCTGCAAA 
ATAAAAAAGT TCAAAGAAAC CTACTTTGTG ATCCTCAGAG CTTGCAGGCT CTGTCAGACC 
TCGGATTCTT TGGACTCAAA CCTTGAACAG ACTACTGAGT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Adora3 ( NM_001302755.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001289684.1 Rattus norvegicus adenosine A3 receptor (Adora3), transcript variant A3i, mRNA.

Price & Availability↑

CloneID	ORa25130
Clone ID Related Accession (Same CDS sequence)	NM_001302755.1
Accession Version	NM_001302755.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1014bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-24
Organism	Rattus norvegicus(Norway rat)
Product	adenosine receptor A3 isoform a
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AABR07012777.1. Transcript Variant: This variant (A3i) represents the longer transcript and encodes the longer isoform (a). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMN00632259, SAMN02642650 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAAGCCA ACAATACCAC GACGAGTGCC TTGTGGTTGC AAATCACCTA CATCACCATG 
GAGGCTGCCA TTGGTCTCTG TGCTGTAGTG GGCAACATGC TGGTCATCTG GGTGGTCAAG 
CTGAACCGCA CTCTGAGGAC CACCACCTTC TATTTCATCG TCTCCCTAGC ACTGGCTGAC 
ATTGCTGTTG GGGTGCTGGT CATACCCTTG GCCATTGCCG TCAGCCTGGA GGTCCAGATG 
CACTTCTATG CCTGCCTTTT CATGTCCTGT GTGCTTCTGG TCTTCACCCA CGCTTCCATC 
ATGTCCTTGC TGGCCATTGC TGTAGACCGA TACCTGCGAG TCAAGCTGAC AGTCAGGTTG 
TCATTTCTTG TTGTGAACTT ACCGTTTTCC TCCCCCCATT CAAACAGATA TAGAACGGTT 
ACCACTCAAA GAAGAATATG GCTATTCCTG GGCCTCTGCT GGCTAGTGTC CTTTCTGGTG 
GGACTGACCC CCATGTTTGG CTGGAATAGA AAAGTGACCT TAGAGCTCTC TCAAAACAGC 
TCCACCCTCT CATGCCACTT CCGTTCCGTG GTCGGCTTGG ATTACATGGT CTTCTTCAGC 
TTCATCACCT GGATCCTCAT CCCCCTGGTT GTCATGTGCA TCATCTATCT GGACATCTTC 
TACATCATCC GAAACAAACT CAGTCAAAAT CTGACTGGCT TCAGAGAGAC GCGTGCATTT 
TACGGTCGGG AGTTCAAGAC CGCTAAGTCC CTGTTTCTGG TTCTCTTCTT GTTTGCCTTG 
TGCTGGCTGC CTTTGTCCAT CATCAATTTT GTTTCCTACT TTAATGTGAA GATACCAGAG 
ATTGCAATGT GCCTGGGCAT CCTGTTGTCC CATGCGAACT CCATGATGAA CCCTATTGTC 
TACGCCTGCA AAATAAAAAA GTTCAAAGAA ACCTACTTTG TGATCCTCAG AGCTTGCAGG 
CTCTGTCAGA CCTCGGATTC TTTGGACTCA AACCTTGAAC AGACTACTGA GTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001289684.1
CDS	316..1329
Translation	MKANNTTTSALWLQITYITMEAAIGLCAVVGNMLVIWVVKLNRTLRTTTFYFIVSLALADIAVGVLVIPLAIAVSLEVQMHFYACLFMSCVLLVFTHASIMSLLAIAVDRYLRVKLTVRLSFLVVNLPFSSPHSNRYRTVTTQRRIWLFLGLCWLVSFLVGLTPMFGWNRKVTLELSQNSSTLSCHFRSVVGLDYMVFFSFITWILIPLVVMCIIYLDIFYIIRNKLSQNLTGFRETRAFYGREFKTAKSLFLVLFLFALCWLPLSIINFVSYFNVKIPEIAMCLGILLSHANSMMNPIVYACKIKKFKETYFVILRACRLCQTSDSLDSNLEQTTE

Target ORF information:

RefSeq Version	NM_001302755.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus adenosine A3 receptor (Adora3), transcript variant A3i, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001302755.1

ORF Insert Sequence:

ATGAAAGCCA ACAATACCAC GACGAGTGCC TTGTGGTTGC AAATCACCTA CATCACCATG 
GAGGCTGCCA TTGGTCTCTG TGCTGTAGTG GGCAACATGC TGGTCATCTG GGTGGTCAAG 
CTGAACCGCA CTCTGAGGAC CACCACCTTC TATTTCATCG TCTCCCTAGC ACTGGCTGAC 
ATTGCTGTTG GGGTGCTGGT CATACCCTTG GCCATTGCCG TCAGCCTGGA GGTCCAGATG 
CACTTCTATG CCTGCCTTTT CATGTCCTGT GTGCTTCTGG TCTTCACCCA CGCTTCCATC 
ATGTCCTTGC TGGCCATTGC TGTAGACCGA TACCTGCGAG TCAAGCTGAC AGTCAGGTTG 
TCATTTCTTG TTGTGAACTT ACCGTTTTCC TCCCCCCATT CAAACAGATA TAGAACGGTT 
ACCACTCAAA GAAGAATATG GCTATTCCTG GGCCTCTGCT GGCTAGTGTC CTTTCTGGTG 
GGACTGACCC CCATGTTTGG CTGGAATAGA AAAGTGACCT TAGAGCTCTC TCAAAACAGC 
TCCACCCTCT CATGCCACTT CCGTTCCGTG GTCGGCTTGG ATTACATGGT CTTCTTCAGC 
TTCATCACCT GGATCCTCAT CCCCCTGGTT GTCATGTGCA TCATCTATCT GGACATCTTC 
TACATCATCC GAAACAAACT CAGTCAAAAT CTGACTGGCT TCAGAGAGAC GCGTGCATTT 
TACGGTCGGG AGTTCAAGAC CGCTAAGTCC CTGTTTCTGG TTCTCTTCTT GTTTGCCTTG 
TGCTGGCTGC CTTTGTCCAT CATCAATTTT GTTTCCTACT TTAATGTGAA GATACCAGAG 
ATTGCAATGT GCCTGGGCAT CCTGTTGTCC CATGCGAACT CCATGATGAA CCCTATTGTC 
TACGCCTGCA AAATAAAAAA GTTCAAAGAA ACCTACTTTG TGATCCTCAG AGCTTGCAGG 
CTCTGTCAGA CCTCGGATTC TTTGGACTCA AACCTTGAAC AGACTACTGA GTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Genome-wide RNAi screening identifies TMIGD3 isoform1 as a suppressor of NF-?B and osteosarcoma progression.
Nature communications713561(2016 Nov)
Iyer SV,Ranjan A,Elias HK,Parrales A,Sasaki H,Roy BC,Umar S,Tawfik OW,Iwakuma T

Adenosine A3 receptor activation is neuroprotective against retinal neurodegeneration.
Experimental eye research14065-74(2015 Nov)
Galvao J,Elvas F,Martins T,Cordeiro MF,Ambr?sio AF,Santiago AR

Evidence for A1 and A 3 receptors mediating adenosine-induced intracellular calcium release in the dorsal root ganglion neurons by using confocal microscopy imaging.
Lasers in medical science29(3)1209-15(2014 May)
Zheng L,Chen J,Huang Y,Wang Y,Yang H,Zhang Y,Xie S

A3 Adenosine receptors mediate oligodendrocyte death and ischemic damage to optic nerve.
Glia62(2)199-216(2014 Feb)
Gonz?lez-Fern?ndez E,S?nchez-G?mez MV,P?rez-Samart?n A,Arellano RO,Matute C

Oxygen/glucose deprivation induces a reduction in synaptic AMPA receptors on hippocampal CA3 neurons mediated by mGluR1 and adenosine A3 receptors.
The Journal of neuroscience : the official journal of the Society for Neuroscience31(33)11941-52(2011 Aug)
Dennis SH,Jaafari N,Cimarosti H,Hanley JG,Henley JM,Mellor JR

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Adora3 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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