Kcnc1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Kcnc1
Entrez Gene ID	25327
Full Name	potassium voltage-gated channel subfamily C member 1
Synonyms	KShIIIB,Kv3.1,Kv4,NGK2-KV4
General protein information	Preferred Names potassium voltage-gated channel subfamily C member 1 Names potassium voltage-gated channel subfamily C member 1 NGK2 Potassium channel gene 1 (alternative splicing product described in Luneau et al 1991) RAW2 potassium channel, voltage gated Shaw-related subfamily C, member 1 potassium voltage gated channel, Shaw-related subfamily, member 1 voltage-gated potassium channel subunit Kv3.1 voltage-gated potassium channel subunit Kv4
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 1 Map Location: 1q22
Summary	voltage gated potassium channel; functions as a delayed rectifier K+ channel [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_017588821.1	XP_017444310.1	potassium voltage-gated channel subfamily C member 1 isoform X1
NM_012856.1	NP_036988.1	potassium voltage-gated channel subfamily C member 1

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	KCNC1	NP_001003113.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP008201	XP_317267.4
Homo sapiens (human)	KCNC1	NP_001106212.1
Gallus gallus (chicken)	KCNC1	XP_004941483.1
Pan troglodytes (chimpanzee)	KCNC1	XP_001172719.2
Rattus norvegicus (Norway rat)	Kcnc1	NP_036988.1
Caenorhabditis elegans (roundworm)	egl-36	NP_509795.1
Bos taurus (cattle)	KCNC1	NP_001106752.1
Danio rerio (zebrafish)	kcnc1a	NP_001122197.1
	KCNC1	XP_001087915.1
Mus musculus (house mouse)	Kcnc1	NP_001106210.1

Gene Ontology
Bibliography

Related articles in PubMed

Identification and characterization of site-specific N-glycosylation in the potassium channel Kv3.1b.
Vicente PC, Kim JY, Ha JJ, Song MY, Lee HK, Kim DH, Choi JS, Park KS
Journal of cellular physiology233(1)549-558(2018 Jan)

Expression of Kv3.1b potassium channel is widespread in macaque motor cortex pyramidal cells: A histological comparison between rat and macaque.
Soares D, Goldrick I, Lemon RN, Kraskov A, Greensmith L, Kalmar B
The Journal of comparative neurology525(9)2164-2174(2017 Jun)

Complex N-Glycans Influence the Spatial Arrangement of Voltage Gated Potassium Channels in Membranes of Neuronal-Derived Cells.
Hall MK, Weidner DA, Edwards MA, Schwalbe RA
PloS one10(9)e0137138(2015)

Src regulates membrane trafficking of the Kv3.1b channel.
Bae SH, Kim DH, Shin SK, Choi JS, Park KS
FEBS letters588(1)86-91(2014 Jan)

Spinocerebellar ataxia-13 Kv3.3 potassium channels: arginine-to-histidine mutations affect both functional and protein expression on the cell surface.
Zhao J, Zhu J, Thornhill WB
The Biochemical journal454(2)259-65(2013 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Trafficking-dependent roles of the Kv3.1b potassium channel are dependent on N229 site-specific glycosylation and N-glycan structure, and operate through a mechanism whereby specific N-glycan structures regulate cell surface expression.
Title: Identification and characterization of site-specific N-glycosylation in the potassium channel Kv3.1b.

This study demonstrated that Kv3.1b potassium channel expression in motor cortex pyramidal cells.
Title: Expression of Kv3.1b potassium channel is widespread in macaque motor cortex pyramidal cells: A histological comparison between rat and macaque.

Our findings provide direct evidence that N-glycans of Kv3.1 splice variants contribute to the placement of these glycoproteins in the plasma membrane of neuronal-derived cells while those of Kv1.1 were absent.
Title: Complex N-Glycans Influence the Spatial Arrangement of Voltage Gated Potassium Channels in Membranes of Neuronal-Derived Cells.

Results indicate that Src kinase may play an important role in regulating membrane trafficking of Kv3.1b channels.
Title: Src regulates membrane trafficking of the Kv3.1b channel.

high-affinity multimeric binding between the Kv3.1 T1 domain and KIF5B requires three basic residues in the KIF5B tail. Kv3.1 T1 competes with the motor domain and microtubules, but not with kinesin light chain 1 (KLC1), for binding to the KIF5B tail.
Title: Activation of conventional kinesin motors in clusters by Shaw voltage-gated K+ channels.

The following Kcnc1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Kcnc1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa13905	NM_012856.1 Latest version!	Rattus norvegicus potassium voltage-gated channel subfamily C member 1 (Kcnc1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$342.30 $489.00
ORa56404	XM_017588821.1 Latest version!	Rattus norvegicus potassium voltage-gated channel subfamily C member 1 (Kcnc1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Kcnc1 ( NM_012856.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_036988.1 Rattus norvegicus potassium voltage-gated channel subfamily C member 1 (Kcnc1), mRNA.

Price & Availability↑

CloneID	ORa13905
Clone ID Related Accession (Same CDS sequence)	NM_012856.1
Accession Version	NM_012856.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1758bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-26
Organism	Rattus norvegicus(Norway rat)
Product	potassium voltage-gated channel subfamily C member 1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from M68880.1. On or before Jun 25, 2006 this sequence version replaced XM_001080138.1, XM_001080128.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: M68880.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGGGCCAAG GGGACGAGAG CGAGCGCATC GTGATCAACG TGGGCGGCAC GCGCCACCAG 
ACGTACCGCT CGACGCTGCG CACGCTGCCC GGCACGCGGC TTGCCTGGCT GGCGGAGCCG 
GACGCCCACA GCCACTTCGA CTATGACCCG CGCGCTGACG AGTTCTTCTT CGACCGCCAC 
CCGGGCGTCT TCGCTCACAT CCTGAACTAT TACCGCACCG GCAAGCTACA CTGCCCGGCC 
GACGTGTGCG GGCCGCTCTA CGAGGAGGAG CTGGCCTTCT GGGGCATCGA CGAGACGGAC 
GTGGAGCCCT GCTGCTGGAT GACGTATCGC CAGCACCGCG ACGCTGAGGA GGCGCTGGAC 
AGCTTTGGTG GCGCGCCCTT GGACAACAGC GCCGACGACG CGGACGCCGA CGGCCCCGGC 
GACTCGGGCG ACGGCGAGGA CGAGCTGGAG ATGACCAAGA GATTGGCGCT CAGTGACTCC 
CCAGATGGCC GGCCTGGCGG CTTCTGGCGC CGCTGGCAGC CACGCATCTG GGCACTGTTC 
GAGGACCCCT ACTCATCCCG CTATGCGCGG TACGTGGCCT TTGCCTCCCT CTTCTTCATC 
CTGGTCTCCA TCACAACCTT CTGTCTGGAG ACCCACGAGC GCTTCAACCC CATCGTGAAC 
AAGACAGAAA TTGAGAACGT TCGAAATGGC ACACAAGTGC GGTACTACCG GGAAGCGGAG 
ACGGAGGCCT TCCTCACCTA CATCGAGGGT GTCTGCGTGG TCTGGTTCAC CTTCGAGTTC 
CTCATGCGTG TTGTCTTCTG TCCCAACAAG GTGGAGTTCA TCAAGAACTC CCTCAATATC 
ATTGACTTCG TGGCCATCCT CCCCTTCTAC CTGGAGGTGG GCCTAAGTGG CCTGTCCTCC 
AAAGCTGCCA AGGACGTGCT AGGCTTCCTG CGCGTCGTGC GCTTCGTGCG CATCCTCCGT 
ATCTTCAAGC TGACCCGCCA TTTTGTGGGC CTGCGGGTCC TGGGCCACAC GCTCCGTGCC 
AGCACCAACG AGTTCCTGCT GCTTATCATC TTCCTGGCCC TGGGTGTGCT CATCTTTGCC 
ACCATGATCT ACTATGCTGA GAGGATAGGG GCACAGCCCA ATGACCCCAG CGCCAGCGAA 
CACACACACT TTAAAAATAT CCCCATCGGC TTCTGGTGGG CTGTGGTCAC CATGACGACA 
CTGGGCTATG GAGACATGTA TCCTCAGACG TGGTCTGGGA TGTTGGTGGG AGCACTGTGC 
GCCCTGGCTG GTGTGCTGAC CATTGCCATG CCGGTGCCCG TCATCGTGAA CAATTTTGGG 
ATGTACTACT CTTTAGCCAT GGCTAAGCAG AAACTACCAA AGAAAAAAAA GAAGCATATT 
CCGCGGCCAC CACAGCTGGG ATCTCCCAAT TATTGTAAAT CTGTCGTAAA CTCTCCACAC 
CACAGTACTC AGAGTGACAC ATGTCCGCTG GCCCAGGAAG AAATTTTAGA AATTAACAGA 
GCAGATTCCA AACTGAATGG GGAGGTGGCG AAGGCCGCGC TGGCGAACGA AGACTGCCCC 
CACATAGACC AGGCCCTCAC TCCCGATGAG GGCCTGCCCT TTACCCGCTC GGGCACCCGC 
GAGAGATACG GACCCTGCTT CCTCTTATCA ACCGGGGAGT ACGCGTGCCC GCCTGGTGGA 
GGAATGAGAA AGGATCTTTG CAAAGAAAGC CCTGTCATTG CTAAGTATAT GCCGACAGAG 
GCTGTGAGAG TGACTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_036988.1
CDS	1162..2919
Translation	MGQGDESERIVINVGGTRHQTYRSTLRTLPGTRLAWLAEPDAHSHFDYDPRADEFFFDRHPGVFAHILNYYRTGKLHCPADVCGPLYEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDSFGGAPLDNSADDADADGPGDSGDGEDELEMTKRLALSDSPDGRPGGFWRRWQPRIWALFEDPYSSRYARYVAFASLFFILVSITTFCLETHERFNPIVNKTEIENVRNGTQVRYYREAETEAFLTYIEGVCVVWFTFEFLMRVVFCPNKVEFIKNSLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGAQPNDPSASEHTHFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKKKHIPRPPQLGSPNYCKSVVNSPHHSTQSDTCPLAQEEILEINRADSKLNGEVAKAALANEDCPHIDQALTPDEGLPFTRSGTRERYGPCFLLSTGEYACPPGGGMRKDLCKESPVIAKYMPTEAVRVT

Target ORF information:

RefSeq Version	NM_012856.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus potassium voltage-gated channel subfamily C member 1 (Kcnc1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_012856.1

ORF Insert Sequence:

ATGGGCCAAG GGGACGAGAG CGAGCGCATC GTGATCAACG TGGGCGGCAC GCGCCACCAG 
ACGTACCGCT CGACGCTGCG CACGCTGCCC GGCACGCGGC TTGCCTGGCT GGCGGAGCCG 
GACGCCCACA GCCACTTCGA CTATGACCCG CGCGCTGACG AGTTCTTCTT CGACCGCCAC 
CCGGGCGTCT TCGCTCACAT CCTGAACTAT TACCGCACCG GCAAGCTACA CTGCCCGGCC 
GACGTGTGCG GGCCGCTCTA CGAGGAGGAG CTGGCCTTCT GGGGCATCGA CGAGACGGAC 
GTGGAGCCCT GCTGCTGGAT GACGTATCGC CAGCACCGCG ACGCTGAGGA GGCGCTGGAC 
AGCTTTGGTG GCGCGCCCTT GGACAACAGC GCCGACGACG CGGACGCCGA CGGCCCCGGC 
GACTCGGGCG ACGGCGAGGA CGAGCTGGAG ATGACCAAGA GATTGGCGCT CAGTGACTCC 
CCAGATGGCC GGCCTGGCGG CTTCTGGCGC CGCTGGCAGC CACGCATCTG GGCACTGTTC 
GAGGACCCCT ACTCATCCCG CTATGCGCGG TACGTGGCCT TTGCCTCCCT CTTCTTCATC 
CTGGTCTCCA TCACAACCTT CTGTCTGGAG ACCCACGAGC GCTTCAACCC CATCGTGAAC 
AAGACAGAAA TTGAGAACGT TCGAAATGGC ACACAAGTGC GGTACTACCG GGAAGCGGAG 
ACGGAGGCCT TCCTCACCTA CATCGAGGGT GTCTGCGTGG TCTGGTTCAC CTTCGAGTTC 
CTCATGCGTG TTGTCTTCTG TCCCAACAAG GTGGAGTTCA TCAAGAACTC CCTCAATATC 
ATTGACTTCG TGGCCATCCT CCCCTTCTAC CTGGAGGTGG GCCTAAGTGG CCTGTCCTCC 
AAAGCTGCCA AGGACGTGCT AGGCTTCCTG CGCGTCGTGC GCTTCGTGCG CATCCTCCGT 
ATCTTCAAGC TGACCCGCCA TTTTGTGGGC CTGCGGGTCC TGGGCCACAC GCTCCGTGCC 
AGCACCAACG AGTTCCTGCT GCTTATCATC TTCCTGGCCC TGGGTGTGCT CATCTTTGCC 
ACCATGATCT ACTATGCTGA GAGGATAGGG GCACAGCCCA ATGACCCCAG CGCCAGCGAA 
CACACACACT TTAAAAATAT CCCCATCGGC TTCTGGTGGG CTGTGGTCAC CATGACGACA 
CTGGGCTATG GAGACATGTA TCCTCAGACG TGGTCTGGGA TGTTGGTGGG AGCACTGTGC 
GCCCTGGCTG GTGTGCTGAC CATTGCCATG CCGGTGCCCG TCATCGTGAA CAATTTTGGG 
ATGTACTACT CTTTAGCCAT GGCTAAGCAG AAACTACCAA AGAAAAAAAA GAAGCATATT 
CCGCGGCCAC CACAGCTGGG ATCTCCCAAT TATTGTAAAT CTGTCGTAAA CTCTCCACAC 
CACAGTACTC AGAGTGACAC ATGTCCGCTG GCCCAGGAAG AAATTTTAGA AATTAACAGA 
GCAGATTCCA AACTGAATGG GGAGGTGGCG AAGGCCGCGC TGGCGAACGA AGACTGCCCC 
CACATAGACC AGGCCCTCAC TCCCGATGAG GGCCTGCCCT TTACCCGCTC GGGCACCCGC 
GAGAGATACG GACCCTGCTT CCTCTTATCA ACCGGGGAGT ACGCGTGCCC GCCTGGTGGA 
GGAATGAGAA AGGATCTTTG CAAAGAAAGC CCTGTCATTG CTAAGTATAT GCCGACAGAG 
GCTGTGAGAG TGACTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Kcnc1 ( XM_017588821.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017444310.1 Rattus norvegicus potassium voltage-gated channel subfamily C member 1 (Kcnc1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa56404
Clone ID Related Accession (Same CDS sequence)	XM_017588821.1
Accession Version	XM_017588821.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1863bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	potassium voltage-gated channel subfamily C member 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGCCAAG GGGACGAGAG CGAGCGCATC GTGATCAACG TGGGCGGCAC GCGCCACCAG 
ACGTACCGCT CGACGCTGCG CACGCTGCCC GGCACGCGGC TTGCCTGGCT GGCGGAGCCG 
GACGCCCACA GCCACTTCGA CTATGACCCG CGCGCTGACG AGTTCTTCTT CGACCGCCAC 
CCGGGCGTCT TCGCTCACAT CCTGAACTAT TACCGCACCG GCAAGCTACA CTGCCCGGCC 
GACGTGTGCG GGCCGCTCTA CGAGGAGGAG CTGGCCTTCT GGGGCATCGA CGAGACGGAC 
GTGGAGCCCT GCTGCTGGAT GACGTATCGC CAGCACCGCG ACGCTGAGGA GGCGCTGGAC 
AGCTTTGGTG GCGCGCCCTT GGACAACAGC GCCGACGACG CGGACGCCGA CGGCCCCGGC 
GACTCGGGCG ACGGCGAGGA CGAGCTGGAG ATGACCAAGA GATTGGCGCT CAGTGACTCC 
CCAGATGGCC GGCCTGGCGG CTTCTGGCGC CGCTGGCAGC CACGCATCTG GGCACTGTTC 
GAGGACCCCT ACTCATCCCG CTATGCGCGG TACGTGGCCT TTGCCTCCCT CTTCTTCATC 
CTGGTCTCCA TCACAACCTT CTGTCTGGAG ACCCACGAGC GCTTCAACCC CATCGTGAAC 
AAGACAGAAA TTGAGAACGT TCGAAATGGC ACACAAGTGC GGTACTACCG GGAAGCGGAG 
ACGGAGGCCT TCCTCACCTA CATCGAGGGT GTCTGCGTGG TCTGGTTCAC CTTCGAGTTC 
CTCATGCGTG TTGTCTTCTG TCCCAACAAG GTGGAGTTCA TCAAGAACTC CCTCAATATC 
ATTGACTTCG TGGCCATCCT CCCCTTCTAC CTGGAGGTGG GCCTAAGTGG CCTGTCCTCC 
AAAGCTGCCA AGGACGTGCT AGGCTTCCTG CGCGTCGTGC GCTTCGTGCG CATCCTCCGT 
ATCTTCAAGC TGACCCGCCA TTTTGTGGGC CTGCGGGTCC TGGGCCACAC GCTCCGTGCC 
AGCACCAACG AGTTCCTGCT GCTTATCATC TTCCTGGCCC TGGGTGTGCT CATCTTTGCC 
ACCATGATCT ACTATGCTGA GAGGATAGGG GCACAGCCCA ATGACCCCAG CGCCAGCGAA 
CACACACACT TTAAAAATAT CCCCATCGGC TTCTGGTGGG CTGTGGTCAC CATGACGACA 
CTGGGCTATG GAGACATGTA TCCTCAGACG TGGTCTGGGA TGTTGGTGGG AGCACTGTGC 
GCCCTGGCTG GTGTGCTGAC CATTGCCATG CCGGTGCCCG TCATCGTGAA CAATTTTGGG 
ATGTACTACT CTTTAGCCAT GGCTAAGCAG AAACTACCAA AGAAAAAAAA GAAGCATATT 
CCGCGGCCAC CACAGCTGGG ATCTCCCAAT TATTGTAAAT CTGTCGTAAA CTCTCCACAC 
CACAGTACTC AGAGTGACAC ATGTCCGCTG GCCCAGGAAG AAATTTTAGA AATTAACAGA 
GCAGATTCCA AACTGAATGG GGAGGTGGCG AAGGCCGCGC TGGCGAACGA AGACTGCCCC 
CACATAGACC AGGCCCTCAC TCCCGATGAG GGCCTGCCCT TTACCCGCTC GGGCACCCGC 
GAGAGATACG GACCCTGCTT CCTCTTATCA ACCGGGGAGT ACGCGTGCCC GCCTGGTGGA 
GGAATGAGAA AGGGAGGGAA GAGAGAGAGG CTGCTAGGCT GGTCCGCTGC ATGGGAAACA 
AGCCAGCTGG AGAAGAACCT GCCTGCCTCT GCATGCGGCT GTTCAGTCTC TCCTCCTCCT 
TCCTTAACAA CTAAGCACCG AGCGAGCGGG AGGGGAAAGC GAGAAGAGGA GCTCAAGTGT 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017444310.1
CDS	1434..3296
Translation	MGQGDESERIVINVGGTRHQTYRSTLRTLPGTRLAWLAEPDAHSHFDYDPRADEFFFDRHPGVFAHILNYYRTGKLHCPADVCGPLYEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDSFGGAPLDNSADDADADGPGDSGDGEDELEMTKRLALSDSPDGRPGGFWRRWQPRIWALFEDPYSSRYARYVAFASLFFILVSITTFCLETHERFNPIVNKTEIENVRNGTQVRYYREAETEAFLTYIEGVCVVWFTFEFLMRVVFCPNKVEFIKNSLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGAQPNDPSASEHTHFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKKKHIPRPPQLGSPNYCKSVVNSPHHSTQSDTCPLAQEEILEINRADSKLNGEVAKAALANEDCPHIDQALTPDEGLPFTRSGTRERYGPCFLLSTGEYACPPGGGMRKGGKRERLLGWSAAWETSQLEKNLPASACGCSVSPPPSLTTKHRASGRGKREEELKC

Target ORF information:

RefSeq Version	XM_017588821.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus potassium voltage-gated channel subfamily C member 1 (Kcnc1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017588821.1

ORF Insert Sequence:

ATGGGCCAAG GGGACGAGAG CGAGCGCATC GTGATCAACG TGGGCGGCAC GCGCCACCAG 
ACGTACCGCT CGACGCTGCG CACGCTGCCC GGCACGCGGC TTGCCTGGCT GGCGGAGCCG 
GACGCCCACA GCCACTTCGA CTATGACCCG CGCGCTGACG AGTTCTTCTT CGACCGCCAC 
CCGGGCGTCT TCGCTCACAT CCTGAACTAT TACCGCACCG GCAAGCTACA CTGCCCGGCC 
GACGTGTGCG GGCCGCTCTA CGAGGAGGAG CTGGCCTTCT GGGGCATCGA CGAGACGGAC 
GTGGAGCCCT GCTGCTGGAT GACGTATCGC CAGCACCGCG ACGCTGAGGA GGCGCTGGAC 
AGCTTTGGTG GCGCGCCCTT GGACAACAGC GCCGACGACG CGGACGCCGA CGGCCCCGGC 
GACTCGGGCG ACGGCGAGGA CGAGCTGGAG ATGACCAAGA GATTGGCGCT CAGTGACTCC 
CCAGATGGCC GGCCTGGCGG CTTCTGGCGC CGCTGGCAGC CACGCATCTG GGCACTGTTC 
GAGGACCCCT ACTCATCCCG CTATGCGCGG TACGTGGCCT TTGCCTCCCT CTTCTTCATC 
CTGGTCTCCA TCACAACCTT CTGTCTGGAG ACCCACGAGC GCTTCAACCC CATCGTGAAC 
AAGACAGAAA TTGAGAACGT TCGAAATGGC ACACAAGTGC GGTACTACCG GGAAGCGGAG 
ACGGAGGCCT TCCTCACCTA CATCGAGGGT GTCTGCGTGG TCTGGTTCAC CTTCGAGTTC 
CTCATGCGTG TTGTCTTCTG TCCCAACAAG GTGGAGTTCA TCAAGAACTC CCTCAATATC 
ATTGACTTCG TGGCCATCCT CCCCTTCTAC CTGGAGGTGG GCCTAAGTGG CCTGTCCTCC 
AAAGCTGCCA AGGACGTGCT AGGCTTCCTG CGCGTCGTGC GCTTCGTGCG CATCCTCCGT 
ATCTTCAAGC TGACCCGCCA TTTTGTGGGC CTGCGGGTCC TGGGCCACAC GCTCCGTGCC 
AGCACCAACG AGTTCCTGCT GCTTATCATC TTCCTGGCCC TGGGTGTGCT CATCTTTGCC 
ACCATGATCT ACTATGCTGA GAGGATAGGG GCACAGCCCA ATGACCCCAG CGCCAGCGAA 
CACACACACT TTAAAAATAT CCCCATCGGC TTCTGGTGGG CTGTGGTCAC CATGACGACA 
CTGGGCTATG GAGACATGTA TCCTCAGACG TGGTCTGGGA TGTTGGTGGG AGCACTGTGC 
GCCCTGGCTG GTGTGCTGAC CATTGCCATG CCGGTGCCCG TCATCGTGAA CAATTTTGGG 
ATGTACTACT CTTTAGCCAT GGCTAAGCAG AAACTACCAA AGAAAAAAAA GAAGCATATT 
CCGCGGCCAC CACAGCTGGG ATCTCCCAAT TATTGTAAAT CTGTCGTAAA CTCTCCACAC 
CACAGTACTC AGAGTGACAC ATGTCCGCTG GCCCAGGAAG AAATTTTAGA AATTAACAGA 
GCAGATTCCA AACTGAATGG GGAGGTGGCG AAGGCCGCGC TGGCGAACGA AGACTGCCCC 
CACATAGACC AGGCCCTCAC TCCCGATGAG GGCCTGCCCT TTACCCGCTC GGGCACCCGC 
GAGAGATACG GACCCTGCTT CCTCTTATCA ACCGGGGAGT ACGCGTGCCC GCCTGGTGGA 
GGAATGAGAA AGGGAGGGAA GAGAGAGAGG CTGCTAGGCT GGTCCGCTGC ATGGGAAACA 
AGCCAGCTGG AGAAGAACCT GCCTGCCTCT GCATGCGGCT GTTCAGTCTC TCCTCCTCCT 
TCCTTAACAA CTAAGCACCG AGCGAGCGGG AGGGGAAAGC GAGAAGAGGA GCTCAAGTGT 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Identification and characterization of site-specific N-glycosylation in the potassium channel Kv3.1b.
Journal of cellular physiology233(1)549-558(2018 Jan)
Vicente PC,Kim JY,Ha JJ,Song MY,Lee HK,Kim DH,Choi JS,Park KS

Expression of Kv3.1b potassium channel is widespread in macaque motor cortex pyramidal cells: A histological comparison between rat and macaque.
The Journal of comparative neurology525(9)2164-2174(2017 Jun)
Soares D,Goldrick I,Lemon RN,Kraskov A,Greensmith L,Kalmar B

Complex N-Glycans Influence the Spatial Arrangement of Voltage Gated Potassium Channels in Membranes of Neuronal-Derived Cells.
PloS one10(9)e0137138(2015)
Hall MK,Weidner DA,Edwards MA,Schwalbe RA

Src regulates membrane trafficking of the Kv3.1b channel.
FEBS letters588(1)86-91(2014 Jan)
Bae SH,Kim DH,Shin SK,Choi JS,Park KS

Spinocerebellar ataxia-13 Kv3.3 potassium channels: arginine-to-histidine mutations affect both functional and protein expression on the cell surface.
The Biochemical journal454(2)259-65(2013 Sep)
Zhao J,Zhu J,Thornhill WB

見積依頼

Eメール

japanmarket@genscript.com

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

Kcnc1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

見積依頼

Eメール

電話

FAX

オンラインフォーム

サポート

会社情報

サポート

会社情報