Stat3 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Stat3
Entrez Gene ID	25125
Full Name	signal transducer and activator of transcription 3
General protein information	Preferred Names signal transducer and activator of transcription 3 Names signal transducer and activator of transcription 3 signal transducer and activator of transcription 3 (acute-phase response factor)
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 10 Map Location: 10q31
Summary	transcription factor that plays a role in induction of gene expression during acute phase response [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_006247257.3	XP_006247319.1	signal transducer and activator of transcription 3 isoform X1
XM_006247258.3	XP_006247320.1	signal transducer and activator of transcription 3 isoform X2
XM_006247259.3	XP_006247321.1	signal transducer and activator of transcription 3 isoform X3
NM_012747.2	NP_036879.1	signal transducer and activator of transcription 3

Pathways from BioSystems

Homologies

	STAT3	XP_002800523.1
Bos taurus (cattle)	STAT3	NP_001012689.2
Mus musculus (house mouse)	Stat3	NP_998824.1
Homo sapiens (human)	STAT3	NP_644805.1
Gallus gallus (chicken)	STAT3	NP_001026102.1
Xenopus tropicalis (tropical clawed frog)	LOC100498278	XP_002941970.2
Pan troglodytes (chimpanzee)	STAT3	XP_001165417.2
Canis lupus familiaris (dog)	STAT3	XP_005624514.1
Danio rerio (zebrafish)	stat3	NP_571554.1
Rattus norvegicus (Norway rat)	Stat3	NP_036879.1

Gene Ontology
Bibliography

Related articles in PubMed

Gene-based anchoring of the rat genetic linkage and cytogenetic maps: new regional localizations, orientation of the linkage groups, and insights into mammalian chromosome evolution.
Szpirer C, Szpirer J, Van Vooren P, Tissir F, Simon JS, Koike G, Jacob HJ, Lander ES, Helou K, Klinga-Levan K, Levan G
Mammalian genome : official journal of the International Mammalian Genome Society9(9)721-34(1998 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

These findings suggest anti-inflammatory roles of CTGF-stimulated tendon stem cells that are likely associated with improved tendon healing.
Title: Tendon stem/progenitor cells regulate inflammation in tendon healing

Studied the fibrotic actions of STAT3 suppression in endothelial cells (ECs); investigated TGF-beta1/ALK5/Smad4 signaling pathway participation; found signaling pathway involvement dependent on TGF-beta1 secretion, the ALK5 activation pathway, and Smad4 translocation into the nucleus.Conclude that suppressed STAT3 expression converts ECs into activated fibroblasts via TGF-beta1/ALK5/Smad4 signaling pathway.
Title: Endothelial fibrosis induced by suppressed STAT3 expression mediated by signaling involving the TGF-?1/ALK5/Smad pathway.

Aldosterone -induced ERK1/2 activation is responsible for STAT3 activation.
Title: Aldosterone activates the oncogenic signals ERK1/2 and STAT3 via redox-regulated mechanisms.

miR-21 overexpression promotes cardiac fibrosis via STAT3 signaling pathway by decrease CADM1 expression, indicating miR-21 as an important signaling molecule for cardiac fibrotic remodeling and atrial fibrillation.
Title: miR-21 enhances cardiac fibrotic remodeling and fibroblast proliferation via CADM1/STAT3 pathway.

Together, these data indicate that novel nongenomic effects of STAT3 influence myocyte energy status and modulate AMPKalpha/mTOR signaling and autophagy to balance the transcriptional hypertrophic response to Ang II stimulation.
Title: STAT3 balances myocyte hypertrophy vis-?-vis autophagy in response to Angiotensin II by modulating the AMPK?/mTOR axis.

The following Stat3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Stat3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa13103	NM_012747.2 Latest version!	Rattus norvegicus signal transducer and activator of transcription 3 (Stat3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$391.30 $559.00
ORa33647	XM_006247257.3 Latest version!	Rattus norvegicus signal transducer and activator of transcription 3 (Stat3), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
ORa33648	XM_006247258.3 Latest version!	Rattus norvegicus signal transducer and activator of transcription 3 (Stat3), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
ORa33649	XM_006247259.3 Latest version!	Rattus norvegicus signal transducer and activator of transcription 3 (Stat3), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Stat3 ( NM_012747.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_036879.1 Rattus norvegicus signal transducer and activator of transcription 3 (Stat3), mRNA.

Price & Availability↑

CloneID	ORa13103
Clone ID Related Accession (Same CDS sequence)	NM_012747.2
Accession Version	NM_012747.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2313bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-15
Organism	Rattus norvegicus(Norway rat)
Product	signal transducer and activator of transcription 3
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC087025.1. On Dec 26, 2004 this sequence version replaced NM_012747.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC087025.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGGCTCAGT GGAACCAGCT CCAGCAGCTG GACACGCGCT ACCTGGAGCA GCTTCATCAG 
CTGTACAGCG ATAGCTTCCC CATGGAGCTG CGGCAGTTCC TGGCGCCTTG GATTGAGAGC 
CAAGATTGGG CATATGCAGC CAGCAAAGAG TCACACGCCA CTCTGGTGTT TCATAACCTC 
TTGGGCGAGA TCGACCAGCA GTATAGCCGA TTCCTGCAGG AGTCCAATGT CCTCTATCAG 
CACAACCTGC GAAGAATCAA GCAGTTCCTG CAGAGCAGGT ATCTTGAGAA GCCAATGGAA 
ATTGCCCGGA TTGTGGCCCG ATGCCTGTGG GAAGAGTCTC GCCTCCTCCA GACGGCAGCC 
ACGGCAGCCC AGCAAGGGGG CCAGGCCAAC CACCCCACAG CTGCCGTAGT GACGGAGAAG 
CAGCAGATGC TGGAACAGCA TCTTCAGGAT GTCCGGAAGC GTGTGCAGGA TCTAGAACAG 
AAAATGAAAG TGGTGGAGAA TCTCCAGGAT GACTTTGATT TCAACTATAA AACCCTCAAG 
AGTCAAGGAG ACATGCAGGA TCTGAATGGA AACAACCAGT CTGTGACCAG ACAGAAGATG 
CAGCAGCTGG AGCAGATGCT CACGGCCCTG GACCAGATGC GGAGGAGCAT CGTGAGCGAG 
CTGGCAGGGC TCTTGTCAGC AATGGAGTAC GTGCAGAAGA CACTGACCGA TGAAGAGCTG 
GCTGACTGGA AGAGGCGGCA GCAGATAGCG TGCATCGGAG GCCCTCCCAA CATCTGCCTG 
GACCGTCTGG AAAACTGGAT AACTTCATTA GCAGAATCTC AACTTCAGAC CCGCCAACAA 
ATTAAGAAAC TGGAGGAGCT GCAGCAGAAA GTGTCCTACA AGGGGGACCC TATTGTGCAG 
CACCGGCCAA TGCTGGAGGA GAGGATCGTG GATCTGTTCA GAAACTTAAT GAAGAGTGCC 
TTCGTGGTGG AGCGGCAGCC CTGTATGCCC ATGCACCCGG ACCGGCCCTT AGTCATCAAG 
ACTGGTGTCC AGTTTACCAC AAAAGTCAGG TTGCTGGTCA AATTTCCTGA GTTGAATTAT 
CAGCTTAAAA TTAAAGTGTG CATTGATAAG GACTCTGGGG ATGTTGCTGC CCTCAGAGGG 
TCTCGGAAAT TTAACATTCT GGGCACGAAC ACAAAGGTGA TGAACATGGA GGAGTCCAAC 
AACGGCAGCC TGTCTGCAGA GTTCAAGCAC CTGACCCTGA GGGAGCAGAG ATGTGGGAAT 
GGGGGCCGTG CCAATTGTGA TGCCTCCTTG ATTGTCACTG AGGAGCTGCA CCTGATCACC 
TTTGAGACAG AGGTGTACCA CCAAGGTCTC AAGATCGACC TAGAGACCCA CTCCTTGCCA 
GTCGTGGTGA TCTCCAACAT CTGTCAGATG CCTAATGCTT GGGCATCAAT CCTGTGGTAT 
AACATGCTGA CCAATAACCC CAAGAACGTG AACTTCTTCA CTAAGCCTCC GATTGGAACC 
TGGGACCAAG TGGCCGAGGT GCTGAGCTGG CAGTTCTCGT CCACCACCAA GCGAGGGCTG 
AGCATCGAGC AGCTGACCAC GCTGGCCGAG AAGCTCTTAG GGCCTGGTGT GAACTACTCA 
GGGTGTCAGA TCACATGGGC TAAGTTTTGC AAAGAAAACA TGGCCGGCAA GGGCTTCTCG 
TTCTGGGTCT GGCTAGACAA TATCATCGAC CTTGTGAAAA AGTATATCTT GGCCCTTTGG 
AATGAAGGGT ACATCATGGG TTTCATCAGC AAGGAGCGGG AGAGGGCCAT CCTAAGCACA 
AAGCCCCCGG GCACCTTCCT GCTGCGGTTC AGTGAGAGCA GCAAGGAAGG AGGGGTCACT 
TTCACTTGGG TGGAAAAGGA CATCAGTGGC AAGACCCAGA TCCAGTCTGT AGAACCATAT 
ACCAAGCAGC AGCTGAACAA CATGTCATTT GCTGAAATCA TCATGGGCTA TAAGATCATG 
GACGCTACCA ACATCCTGGT ATCCCCACTG GTCTACCTCT ACCCTGACAT TCCCAAGGAG 
GAGGCATTCG GAAAGTATTG TCGCCCCGAG AGCCAGGAGC ACCCTGAAGC TGACCCAGGT 
AGTGCTGCCC CTTACCTGAA GACCAAGTTC ATCTGTGTGA CACCAACGAC CTGCAGCAAT 
ACCATTGACC TGCCGATGTC CCCCCGCACT TTAGATTCAT TGATGCAGTT TGGAAATAAC 
GGGGAAGGCG CTGAGCCCTC AGCAGGAGGG CAGTTTGAGT CGCTCACGTT TGACATGGAT 
CTGACCTCGG AGTGTGCTAC CTCCCCGATG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_036879.1
CDS	207..2519
Translation	MAQWNQLQQLDTRYLEQLHQLYSDSFPMELRQFLAPWIESQDWAYAASKESHATLVFHNLLGEIDQQYSRFLQESNVLYQHNLRRIKQFLQSRYLEKPMEIARIVARCLWEESRLLQTAATAAQQGGQANHPTAAVVTEKQQMLEQHLQDVRKRVQDLEQKMKVVENLQDDFDFNYKTLKSQGDMQDLNGNNQSVTRQKMQQLEQMLTALDQMRRSIVSELAGLLSAMEYVQKTLTDEELADWKRRQQIACIGGPPNICLDRLENWITSLAESQLQTRQQIKKLEELQQKVSYKGDPIVQHRPMLEERIVDLFRNLMKSAFVVERQPCMPMHPDRPLVIKTGVQFTTKVRLLVKFPELNYQLKIKVCIDKDSGDVAALRGSRKFNILGTNTKVMNMEESNNGSLSAEFKHLTLREQRCGNGGRANCDASLIVTEELHLITFETEVYHQGLKIDLETHSLPVVVISNICQMPNAWASILWYNMLTNNPKNVNFFTKPPIGTWDQVAEVLSWQFSSTTKRGLSIEQLTTLAEKLLGPGVNYSGCQITWAKFCKENMAGKGFSFWVWLDNIIDLVKKYILALWNEGYIMGFISKERERAILSTKPPGTFLLRFSESSKEGGVTFTWVEKDISGKTQIQSVEPYTKQQLNNMSFAEIIMGYKIMDATNILVSPLVYLYPDIPKEEAFGKYCRPESQEHPEADPGSAAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNNGEGAEPSAGGQFESLTFDMDLTSECATSPM

Target ORF information:

RefSeq Version	NM_012747.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus signal transducer and activator of transcription 3 (Stat3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_012747.2

ORF Insert Sequence:

ATGGCTCAGT GGAACCAGCT CCAGCAGCTG GACACGCGCT ACCTGGAGCA GCTTCATCAG 
CTGTACAGCG ATAGCTTCCC CATGGAGCTG CGGCAGTTCC TGGCGCCTTG GATTGAGAGC 
CAAGATTGGG CATATGCAGC CAGCAAAGAG TCACACGCCA CTCTGGTGTT TCATAACCTC 
TTGGGCGAGA TCGACCAGCA GTATAGCCGA TTCCTGCAGG AGTCCAATGT CCTCTATCAG 
CACAACCTGC GAAGAATCAA GCAGTTCCTG CAGAGCAGGT ATCTTGAGAA GCCAATGGAA 
ATTGCCCGGA TTGTGGCCCG ATGCCTGTGG GAAGAGTCTC GCCTCCTCCA GACGGCAGCC 
ACGGCAGCCC AGCAAGGGGG CCAGGCCAAC CACCCCACAG CTGCCGTAGT GACGGAGAAG 
CAGCAGATGC TGGAACAGCA TCTTCAGGAT GTCCGGAAGC GTGTGCAGGA TCTAGAACAG 
AAAATGAAAG TGGTGGAGAA TCTCCAGGAT GACTTTGATT TCAACTATAA AACCCTCAAG 
AGTCAAGGAG ACATGCAGGA TCTGAATGGA AACAACCAGT CTGTGACCAG ACAGAAGATG 
CAGCAGCTGG AGCAGATGCT CACGGCCCTG GACCAGATGC GGAGGAGCAT CGTGAGCGAG 
CTGGCAGGGC TCTTGTCAGC AATGGAGTAC GTGCAGAAGA CACTGACCGA TGAAGAGCTG 
GCTGACTGGA AGAGGCGGCA GCAGATAGCG TGCATCGGAG GCCCTCCCAA CATCTGCCTG 
GACCGTCTGG AAAACTGGAT AACTTCATTA GCAGAATCTC AACTTCAGAC CCGCCAACAA 
ATTAAGAAAC TGGAGGAGCT GCAGCAGAAA GTGTCCTACA AGGGGGACCC TATTGTGCAG 
CACCGGCCAA TGCTGGAGGA GAGGATCGTG GATCTGTTCA GAAACTTAAT GAAGAGTGCC 
TTCGTGGTGG AGCGGCAGCC CTGTATGCCC ATGCACCCGG ACCGGCCCTT AGTCATCAAG 
ACTGGTGTCC AGTTTACCAC AAAAGTCAGG TTGCTGGTCA AATTTCCTGA GTTGAATTAT 
CAGCTTAAAA TTAAAGTGTG CATTGATAAG GACTCTGGGG ATGTTGCTGC CCTCAGAGGG 
TCTCGGAAAT TTAACATTCT GGGCACGAAC ACAAAGGTGA TGAACATGGA GGAGTCCAAC 
AACGGCAGCC TGTCTGCAGA GTTCAAGCAC CTGACCCTGA GGGAGCAGAG ATGTGGGAAT 
GGGGGCCGTG CCAATTGTGA TGCCTCCTTG ATTGTCACTG AGGAGCTGCA CCTGATCACC 
TTTGAGACAG AGGTGTACCA CCAAGGTCTC AAGATCGACC TAGAGACCCA CTCCTTGCCA 
GTCGTGGTGA TCTCCAACAT CTGTCAGATG CCTAATGCTT GGGCATCAAT CCTGTGGTAT 
AACATGCTGA CCAATAACCC CAAGAACGTG AACTTCTTCA CTAAGCCTCC GATTGGAACC 
TGGGACCAAG TGGCCGAGGT GCTGAGCTGG CAGTTCTCGT CCACCACCAA GCGAGGGCTG 
AGCATCGAGC AGCTGACCAC GCTGGCCGAG AAGCTCTTAG GGCCTGGTGT GAACTACTCA 
GGGTGTCAGA TCACATGGGC TAAGTTTTGC AAAGAAAACA TGGCCGGCAA GGGCTTCTCG 
TTCTGGGTCT GGCTAGACAA TATCATCGAC CTTGTGAAAA AGTATATCTT GGCCCTTTGG 
AATGAAGGGT ACATCATGGG TTTCATCAGC AAGGAGCGGG AGAGGGCCAT CCTAAGCACA 
AAGCCCCCGG GCACCTTCCT GCTGCGGTTC AGTGAGAGCA GCAAGGAAGG AGGGGTCACT 
TTCACTTGGG TGGAAAAGGA CATCAGTGGC AAGACCCAGA TCCAGTCTGT AGAACCATAT 
ACCAAGCAGC AGCTGAACAA CATGTCATTT GCTGAAATCA TCATGGGCTA TAAGATCATG 
GACGCTACCA ACATCCTGGT ATCCCCACTG GTCTACCTCT ACCCTGACAT TCCCAAGGAG 
GAGGCATTCG GAAAGTATTG TCGCCCCGAG AGCCAGGAGC ACCCTGAAGC TGACCCAGGT 
AGTGCTGCCC CTTACCTGAA GACCAAGTTC ATCTGTGTGA CACCAACGAC CTGCAGCAAT 
ACCATTGACC TGCCGATGTC CCCCCGCACT TTAGATTCAT TGATGCAGTT TGGAAATAAC 
GGGGAAGGCG CTGAGCCCTC AGCAGGAGGG CAGTTTGAGT CGCTCACGTT TGACATGGAT 
CTGACCTCGG AGTGTGCTAC CTCCCCGATG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Stat3 ( XM_006247257.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006247319.1 Rattus norvegicus signal transducer and activator of transcription 3 (Stat3), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa33647
Clone ID Related Accession (Same CDS sequence)	XM_006247257.3
Accession Version	XM_006247257.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2310bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	signal transducer and activator of transcription 3 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005109.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006247257.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTCAGT GGAACCAGCT CCAGCAGCTG GACACGCGCT ACCTGGAGCA GCTTCATCAG 
CTGTACAGCG ATAGCTTCCC CATGGAGCTG CGGCAGTTCC TGGCGCCTTG GATTGAGAGC 
CAAGATTGGG CATATGCAGC CAGCAAAGAG TCACACGCCA CTCTGGTGTT TCATAACCTC 
TTGGGCGAGA TCGACCAGCA GTATAGCCGA TTCCTGCAGG AGTCCAATGT CCTCTATCAG 
CACAACCTGC GAAGAATCAA GCAGTTCCTG CAGAGCAGGT ATCTTGAGAA GCCAATGGAA 
ATTGCCCGGA TTGTGGCCCG ATGCCTGTGG GAAGAGTCTC GCCTCCTCCA GACGGCAGCC 
ACGGCAGCCC AGCAAGGGGG CCAGGCCAAC CACCCCACAG CTGCCGTAGT GACGGAGAAG 
CAGCAGATGC TGGAACAGCA TCTTCAGGAT GTCCGGAAGC GTGTGCAGGA TCTAGAACAG 
AAAATGAAAG TGGTGGAGAA TCTCCAGGAT GACTTTGATT TCAACTATAA AACCCTCAAG 
AGTCAAGGAG ACATGCAGGA TCTGAATGGA AACAACCAGT CTGTGACCAG ACAGAAGATG 
CAGCAGCTGG AGCAGATGCT CACGGCCCTG GACCAGATGC GGAGGAGCAT CGTGAGCGAG 
CTGGCAGGGC TCTTGTCAGC AATGGAGTAC GTGCAGAAGA CACTGACCGA TGAAGAGCTG 
GCTGACTGGA AGAGGCGGCA GCAGATAGCG TGCATCGGAG GCCCTCCCAA CATCTGCCTG 
GACCGTCTGG AAAACTGGAT AACTTCATTA GCAGAATCTC AACTTCAGAC CCGCCAACAA 
ATTAAGAAAC TGGAGGAGCT GCAGCAGAAA GTGTCCTACA AGGGGGACCC TATTGTGCAG 
CACCGGCCAA TGCTGGAGGA GAGGATCGTG GATCTGTTCA GAAACTTAAT GAAGAGTGCC 
TTCGTGGTGG AGCGGCAGCC CTGTATGCCC ATGCACCCGG ACCGGCCCTT AGTCATCAAG 
ACTGGTGTCC AGTTTACCAC AAAAGTCAGG TTGCTGGTCA AATTTCCTGA GTTGAATTAT 
CAGCTTAAAA TTAAAGTGTG CATTGATAAG GACTCTGGGG ATGTTGCTGC CCTCAGAGGG 
TCTCGGAAAT TTAACATTCT GGGCACGAAC ACAAAGGTGA TGAACATGGA GGAGTCCAAC 
AACGGCAGCC TGTCTGCAGA GTTCAAGCAC CTGACCCTGA GGGAGCAGAG ATGTGGGAAT 
GGGGGCCGTG CCAATTGTGA TGCCTCCTTG ATTGTCACTG AGGAGCTGCA CCTGATCACC 
TTTGAGACAG AGGTGTACCA CCAAGGTCTC AAGATCGACC TAGAGACCCA CTCCTTGCCA 
GTCGTGGTGA TCTCCAACAT CTGTCAGATG CCTAATGCTT GGGCATCAAT CCTGTGGTAT 
AACATGCTGA CCAATAACCC CAAGAACGTG AACTTCTTCA CTAAGCCTCC GATTGGAACC 
TGGGACCAAG TGGCCGAGGT GCTGAGCTGG CAGTTCTCGT CCACCACCAA GCGAGGGCTG 
AGCATCGAGC AGCTGACCAC GCTGGCCGAG AAGCTCTTAG GGCCTGGTGT GAACTACTCA 
GGGTGTCAGA TCACATGGGC TAAGTTTTGC AAAGAAAACA TGGCCGGCAA GGGCTTCTCG 
TTCTGGGTCT GGCTAGACAA TATCATCGAC CTTGTGAAAA AGTATATCTT GGCCCTTTGG 
AATGAAGGGT ACATCATGGG TTTCATCAGC AAGGAGCGGG AGAGGGCCAT CCTAAGCACA 
AAGCCCCCGG GCACCTTCCT GCTGCGGTTC AGTGAGAGCA GCAAGGAAGG AGGGGTCACT 
TTCACTTGGG TGGAAAAGGA CATCAGTGGC AAGACCCAGA TCCAGTCTGT AGAACCATAT 
ACCAAGCAGC AGCTGAACAA CATGTCATTT GCTGAAATCA TCATGGGCTA TAAGATCATG 
GACGCTACCA ACATCCTGGT ATCCCCACTG GTCTACCTCT ACCCTGACAT TCCCAAGGAG 
GAGGCATTCG GAAAGTATTG TCGCCCCGAG AGCCAGGAGC ACCCTGAAGC TGACCCAGGT 
GCTGCCCCTT ACCTGAAGAC CAAGTTCATC TGTGTGACAC CAACGACCTG CAGCAATACC 
ATTGACCTGC CGATGTCCCC CCGCACTTTA GATTCATTGA TGCAGTTTGG AAATAACGGG 
GAAGGCGCTG AGCCCTCAGC AGGAGGGCAG TTTGAGTCGC TCACGTTTGA CATGGATCTG 
ACCTCGGAGT GTGCTACCTC CCCGATGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006247319.1
CDS	237..2546
Translation	MAQWNQLQQLDTRYLEQLHQLYSDSFPMELRQFLAPWIESQDWAYAASKESHATLVFHNLLGEIDQQYSRFLQESNVLYQHNLRRIKQFLQSRYLEKPMEIARIVARCLWEESRLLQTAATAAQQGGQANHPTAAVVTEKQQMLEQHLQDVRKRVQDLEQKMKVVENLQDDFDFNYKTLKSQGDMQDLNGNNQSVTRQKMQQLEQMLTALDQMRRSIVSELAGLLSAMEYVQKTLTDEELADWKRRQQIACIGGPPNICLDRLENWITSLAESQLQTRQQIKKLEELQQKVSYKGDPIVQHRPMLEERIVDLFRNLMKSAFVVERQPCMPMHPDRPLVIKTGVQFTTKVRLLVKFPELNYQLKIKVCIDKDSGDVAALRGSRKFNILGTNTKVMNMEESNNGSLSAEFKHLTLREQRCGNGGRANCDASLIVTEELHLITFETEVYHQGLKIDLETHSLPVVVISNICQMPNAWASILWYNMLTNNPKNVNFFTKPPIGTWDQVAEVLSWQFSSTTKRGLSIEQLTTLAEKLLGPGVNYSGCQITWAKFCKENMAGKGFSFWVWLDNIIDLVKKYILALWNEGYIMGFISKERERAILSTKPPGTFLLRFSESSKEGGVTFTWVEKDISGKTQIQSVEPYTKQQLNNMSFAEIIMGYKIMDATNILVSPLVYLYPDIPKEEAFGKYCRPESQEHPEADPGAAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNNGEGAEPSAGGQFESLTFDMDLTSECATSPM

Target ORF information:

RefSeq Version	XM_006247257.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus signal transducer and activator of transcription 3 (Stat3), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006247257.3

ORF Insert Sequence:

ATGGCTCAGT GGAACCAGCT CCAGCAGCTG GACACGCGCT ACCTGGAGCA GCTTCATCAG 
CTGTACAGCG ATAGCTTCCC CATGGAGCTG CGGCAGTTCC TGGCGCCTTG GATTGAGAGC 
CAAGATTGGG CATATGCAGC CAGCAAAGAG TCACACGCCA CTCTGGTGTT TCATAACCTC 
TTGGGCGAGA TCGACCAGCA GTATAGCCGA TTCCTGCAGG AGTCCAATGT CCTCTATCAG 
CACAACCTGC GAAGAATCAA GCAGTTCCTG CAGAGCAGGT ATCTTGAGAA GCCAATGGAA 
ATTGCCCGGA TTGTGGCCCG ATGCCTGTGG GAAGAGTCTC GCCTCCTCCA GACGGCAGCC 
ACGGCAGCCC AGCAAGGGGG CCAGGCCAAC CACCCCACAG CTGCCGTAGT GACGGAGAAG 
CAGCAGATGC TGGAACAGCA TCTTCAGGAT GTCCGGAAGC GTGTGCAGGA TCTAGAACAG 
AAAATGAAAG TGGTGGAGAA TCTCCAGGAT GACTTTGATT TCAACTATAA AACCCTCAAG 
AGTCAAGGAG ACATGCAGGA TCTGAATGGA AACAACCAGT CTGTGACCAG ACAGAAGATG 
CAGCAGCTGG AGCAGATGCT CACGGCCCTG GACCAGATGC GGAGGAGCAT CGTGAGCGAG 
CTGGCAGGGC TCTTGTCAGC AATGGAGTAC GTGCAGAAGA CACTGACCGA TGAAGAGCTG 
GCTGACTGGA AGAGGCGGCA GCAGATAGCG TGCATCGGAG GCCCTCCCAA CATCTGCCTG 
GACCGTCTGG AAAACTGGAT AACTTCATTA GCAGAATCTC AACTTCAGAC CCGCCAACAA 
ATTAAGAAAC TGGAGGAGCT GCAGCAGAAA GTGTCCTACA AGGGGGACCC TATTGTGCAG 
CACCGGCCAA TGCTGGAGGA GAGGATCGTG GATCTGTTCA GAAACTTAAT GAAGAGTGCC 
TTCGTGGTGG AGCGGCAGCC CTGTATGCCC ATGCACCCGG ACCGGCCCTT AGTCATCAAG 
ACTGGTGTCC AGTTTACCAC AAAAGTCAGG TTGCTGGTCA AATTTCCTGA GTTGAATTAT 
CAGCTTAAAA TTAAAGTGTG CATTGATAAG GACTCTGGGG ATGTTGCTGC CCTCAGAGGG 
TCTCGGAAAT TTAACATTCT GGGCACGAAC ACAAAGGTGA TGAACATGGA GGAGTCCAAC 
AACGGCAGCC TGTCTGCAGA GTTCAAGCAC CTGACCCTGA GGGAGCAGAG ATGTGGGAAT 
GGGGGCCGTG CCAATTGTGA TGCCTCCTTG ATTGTCACTG AGGAGCTGCA CCTGATCACC 
TTTGAGACAG AGGTGTACCA CCAAGGTCTC AAGATCGACC TAGAGACCCA CTCCTTGCCA 
GTCGTGGTGA TCTCCAACAT CTGTCAGATG CCTAATGCTT GGGCATCAAT CCTGTGGTAT 
AACATGCTGA CCAATAACCC CAAGAACGTG AACTTCTTCA CTAAGCCTCC GATTGGAACC 
TGGGACCAAG TGGCCGAGGT GCTGAGCTGG CAGTTCTCGT CCACCACCAA GCGAGGGCTG 
AGCATCGAGC AGCTGACCAC GCTGGCCGAG AAGCTCTTAG GGCCTGGTGT GAACTACTCA 
GGGTGTCAGA TCACATGGGC TAAGTTTTGC AAAGAAAACA TGGCCGGCAA GGGCTTCTCG 
TTCTGGGTCT GGCTAGACAA TATCATCGAC CTTGTGAAAA AGTATATCTT GGCCCTTTGG 
AATGAAGGGT ACATCATGGG TTTCATCAGC AAGGAGCGGG AGAGGGCCAT CCTAAGCACA 
AAGCCCCCGG GCACCTTCCT GCTGCGGTTC AGTGAGAGCA GCAAGGAAGG AGGGGTCACT 
TTCACTTGGG TGGAAAAGGA CATCAGTGGC AAGACCCAGA TCCAGTCTGT AGAACCATAT 
ACCAAGCAGC AGCTGAACAA CATGTCATTT GCTGAAATCA TCATGGGCTA TAAGATCATG 
GACGCTACCA ACATCCTGGT ATCCCCACTG GTCTACCTCT ACCCTGACAT TCCCAAGGAG 
GAGGCATTCG GAAAGTATTG TCGCCCCGAG AGCCAGGAGC ACCCTGAAGC TGACCCAGGT 
GCTGCCCCTT ACCTGAAGAC CAAGTTCATC TGTGTGACAC CAACGACCTG CAGCAATACC 
ATTGACCTGC CGATGTCCCC CCGCACTTTA GATTCATTGA TGCAGTTTGG AAATAACGGG 
GAAGGCGCTG AGCCCTCAGC AGGAGGGCAG TTTGAGTCGC TCACGTTTGA CATGGATCTG 
ACCTCGGAGT GTGCTACCTC CCCGATGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Stat3 ( XM_006247258.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006247320.1 Rattus norvegicus signal transducer and activator of transcription 3 (Stat3), transcript variant X2, mRNA.

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CloneID	ORa33648
Clone ID Related Accession (Same CDS sequence)	XM_006247258.3
Accession Version	XM_006247258.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2169bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	signal transducer and activator of transcription 3 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005109.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006247258.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTCAGT GGAACCAGCT CCAGCAGCTG GACACGCGCT ACCTGGAGCA GCTTCATCAG 
CTGTACAGCG ATAGCTTCCC CATGGAGCTG CGGCAGTTCC TGGCGCCTTG GATTGAGAGC 
CAAGATTGGG CATATGCAGC CAGCAAAGAG TCACACGCCA CTCTGGTGTT TCATAACCTC 
TTGGGCGAGA TCGACCAGCA GTATAGCCGA TTCCTGCAGG AGTCCAATGT CCTCTATCAG 
CACAACCTGC GAAGAATCAA GCAGTTCCTG CAGAGCAGGT ATCTTGAGAA GCCAATGGAA 
ATTGCCCGGA TTGTGGCCCG ATGCCTGTGG GAAGAGTCTC GCCTCCTCCA GACGGCAGCC 
ACGGCAGCCC AGCAAGGGGG CCAGGCCAAC CACCCCACAG CTGCCGTAGT GACGGAGAAG 
CAGCAGATGC TGGAACAGCA TCTTCAGGAT GTCCGGAAGC GTGTGCAGGA TCTAGAACAG 
AAAATGAAAG TGGTGGAGAA TCTCCAGGAT GACTTTGATT TCAACTATAA AACCCTCAAG 
AGTCAAGGAG ACATGCAGGA TCTGAATGGA AACAACCAGT CTGTGACCAG ACAGAAGATG 
CAGCAGCTGG AGCAGATGCT CACGGCCCTG GACCAGATGC GGAGGAGCAT CGTGAGCGAG 
CTGGCAGGGC TCTTGTCAGC AATGGAGTAC GTGCAGAAGA CACTGACCGA TGAAGAGCTG 
GCTGACTGGA AGAGGCGGCA GCAGATAGCG TGCATCGGAG GCCCTCCCAA CATCTGCCTG 
GACCGTCTGG AAAACTGGAT AACTTCATTA GCAGAATCTC AACTTCAGAC CCGCCAACAA 
ATTAAGAAAC TGGAGGAGCT GCAGCAGAAA GTGTCCTACA AGGGGGACCC TATTGTGCAG 
CACCGGCCAA TGCTGGAGGA GAGGATCGTG GATCTGTTCA GAAACTTAAT GAAGAGTGCC 
TTCGTGGTGG AGCGGCAGCC CTGTATGCCC ATGCACCCGG ACCGGCCCTT AGTCATCAAG 
ACTGGTGTCC AGTTTACCAC AAAAGTCAGG TTGCTGGTCA AATTTCCTGA GTTGAATTAT 
CAGCTTAAAA TTAAAGTGTG CATTGATAAG GACTCTGGGG ATGTTGCTGC CCTCAGAGGG 
TCTCGGAAAT TTAACATTCT GGGCACGAAC ACAAAGGTGA TGAACATGGA GGAGTCCAAC 
AACGGCAGCC TGTCTGCAGA GTTCAAGCAC CTGACCCTGA GGGAGCAGAG ATGTGGGAAT 
GGGGGCCGTG CCAATTGTGA TGCCTCCTTG ATTGTCACTG AGGAGCTGCA CCTGATCACC 
TTTGAGACAG AGGTGTACCA CCAAGGTCTC AAGATCGACC TAGAGACCCA CTCCTTGCCA 
GTCGTGGTGA TCTCCAACAT CTGTCAGATG CCTAATGCTT GGGCATCAAT CCTGTGGTAT 
AACATGCTGA CCAATAACCC CAAGAACGTG AACTTCTTCA CTAAGCCTCC GATTGGAACC 
TGGGACCAAG TGGCCGAGGT GCTGAGCTGG CAGTTCTCGT CCACCACCAA GCGAGGGCTG 
AGCATCGAGC AGCTGACCAC GCTGGCCGAG AAGCTCTTAG GGCCTGGTGT GAACTACTCA 
GGGTGTCAGA TCACATGGGC TAAGTTTTGC AAAGAAAACA TGGCCGGCAA GGGCTTCTCG 
TTCTGGGTCT GGCTAGACAA TATCATCGAC CTTGTGAAAA AGTATATCTT GGCCCTTTGG 
AATGAAGGGT ACATCATGGG TTTCATCAGC AAGGAGCGGG AGAGGGCCAT CCTAAGCACA 
AAGCCCCCGG GCACCTTCCT GCTGCGGTTC AGTGAGAGCA GCAAGGAAGG AGGGGTCACT 
TTCACTTGGG TGGAAAAGGA CATCAGTGGC AAGACCCAGA TCCAGTCTGT AGAACCATAT 
ACCAAGCAGC AGCTGAACAA CATGTCATTT GCTGAAATCA TCATGGGCTA TAAGATCATG 
GACGCTACCA ACATCCTGGT ATCCCCACTG GTCTACCTCT ACCCTGACAT TCCCAAGGAG 
GAGGCATTCG GAAAGTATTG TCGCCCCGAG AGCCAGGAGC ACCCTGAAGC TGACCCAGGT 
AGTGCTGCCC CTTACCTGAA GACCAAGTTC ATCTGTGTGA CACCATTCAT TGATGCAGTT 
TGGAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006247320.1
CDS	237..2405
Translation	MAQWNQLQQLDTRYLEQLHQLYSDSFPMELRQFLAPWIESQDWAYAASKESHATLVFHNLLGEIDQQYSRFLQESNVLYQHNLRRIKQFLQSRYLEKPMEIARIVARCLWEESRLLQTAATAAQQGGQANHPTAAVVTEKQQMLEQHLQDVRKRVQDLEQKMKVVENLQDDFDFNYKTLKSQGDMQDLNGNNQSVTRQKMQQLEQMLTALDQMRRSIVSELAGLLSAMEYVQKTLTDEELADWKRRQQIACIGGPPNICLDRLENWITSLAESQLQTRQQIKKLEELQQKVSYKGDPIVQHRPMLEERIVDLFRNLMKSAFVVERQPCMPMHPDRPLVIKTGVQFTTKVRLLVKFPELNYQLKIKVCIDKDSGDVAALRGSRKFNILGTNTKVMNMEESNNGSLSAEFKHLTLREQRCGNGGRANCDASLIVTEELHLITFETEVYHQGLKIDLETHSLPVVVISNICQMPNAWASILWYNMLTNNPKNVNFFTKPPIGTWDQVAEVLSWQFSSTTKRGLSIEQLTTLAEKLLGPGVNYSGCQITWAKFCKENMAGKGFSFWVWLDNIIDLVKKYILALWNEGYIMGFISKERERAILSTKPPGTFLLRFSESSKEGGVTFTWVEKDISGKTQIQSVEPYTKQQLNNMSFAEIIMGYKIMDATNILVSPLVYLYPDIPKEEAFGKYCRPESQEHPEADPGSAAPYLKTKFICVTPFIDAVWK

Target ORF information:

RefSeq Version	XM_006247258.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus signal transducer and activator of transcription 3 (Stat3), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006247258.3

ORF Insert Sequence:

ATGGCTCAGT GGAACCAGCT CCAGCAGCTG GACACGCGCT ACCTGGAGCA GCTTCATCAG 
CTGTACAGCG ATAGCTTCCC CATGGAGCTG CGGCAGTTCC TGGCGCCTTG GATTGAGAGC 
CAAGATTGGG CATATGCAGC CAGCAAAGAG TCACACGCCA CTCTGGTGTT TCATAACCTC 
TTGGGCGAGA TCGACCAGCA GTATAGCCGA TTCCTGCAGG AGTCCAATGT CCTCTATCAG 
CACAACCTGC GAAGAATCAA GCAGTTCCTG CAGAGCAGGT ATCTTGAGAA GCCAATGGAA 
ATTGCCCGGA TTGTGGCCCG ATGCCTGTGG GAAGAGTCTC GCCTCCTCCA GACGGCAGCC 
ACGGCAGCCC AGCAAGGGGG CCAGGCCAAC CACCCCACAG CTGCCGTAGT GACGGAGAAG 
CAGCAGATGC TGGAACAGCA TCTTCAGGAT GTCCGGAAGC GTGTGCAGGA TCTAGAACAG 
AAAATGAAAG TGGTGGAGAA TCTCCAGGAT GACTTTGATT TCAACTATAA AACCCTCAAG 
AGTCAAGGAG ACATGCAGGA TCTGAATGGA AACAACCAGT CTGTGACCAG ACAGAAGATG 
CAGCAGCTGG AGCAGATGCT CACGGCCCTG GACCAGATGC GGAGGAGCAT CGTGAGCGAG 
CTGGCAGGGC TCTTGTCAGC AATGGAGTAC GTGCAGAAGA CACTGACCGA TGAAGAGCTG 
GCTGACTGGA AGAGGCGGCA GCAGATAGCG TGCATCGGAG GCCCTCCCAA CATCTGCCTG 
GACCGTCTGG AAAACTGGAT AACTTCATTA GCAGAATCTC AACTTCAGAC CCGCCAACAA 
ATTAAGAAAC TGGAGGAGCT GCAGCAGAAA GTGTCCTACA AGGGGGACCC TATTGTGCAG 
CACCGGCCAA TGCTGGAGGA GAGGATCGTG GATCTGTTCA GAAACTTAAT GAAGAGTGCC 
TTCGTGGTGG AGCGGCAGCC CTGTATGCCC ATGCACCCGG ACCGGCCCTT AGTCATCAAG 
ACTGGTGTCC AGTTTACCAC AAAAGTCAGG TTGCTGGTCA AATTTCCTGA GTTGAATTAT 
CAGCTTAAAA TTAAAGTGTG CATTGATAAG GACTCTGGGG ATGTTGCTGC CCTCAGAGGG 
TCTCGGAAAT TTAACATTCT GGGCACGAAC ACAAAGGTGA TGAACATGGA GGAGTCCAAC 
AACGGCAGCC TGTCTGCAGA GTTCAAGCAC CTGACCCTGA GGGAGCAGAG ATGTGGGAAT 
GGGGGCCGTG CCAATTGTGA TGCCTCCTTG ATTGTCACTG AGGAGCTGCA CCTGATCACC 
TTTGAGACAG AGGTGTACCA CCAAGGTCTC AAGATCGACC TAGAGACCCA CTCCTTGCCA 
GTCGTGGTGA TCTCCAACAT CTGTCAGATG CCTAATGCTT GGGCATCAAT CCTGTGGTAT 
AACATGCTGA CCAATAACCC CAAGAACGTG AACTTCTTCA CTAAGCCTCC GATTGGAACC 
TGGGACCAAG TGGCCGAGGT GCTGAGCTGG CAGTTCTCGT CCACCACCAA GCGAGGGCTG 
AGCATCGAGC AGCTGACCAC GCTGGCCGAG AAGCTCTTAG GGCCTGGTGT GAACTACTCA 
GGGTGTCAGA TCACATGGGC TAAGTTTTGC AAAGAAAACA TGGCCGGCAA GGGCTTCTCG 
TTCTGGGTCT GGCTAGACAA TATCATCGAC CTTGTGAAAA AGTATATCTT GGCCCTTTGG 
AATGAAGGGT ACATCATGGG TTTCATCAGC AAGGAGCGGG AGAGGGCCAT CCTAAGCACA 
AAGCCCCCGG GCACCTTCCT GCTGCGGTTC AGTGAGAGCA GCAAGGAAGG AGGGGTCACT 
TTCACTTGGG TGGAAAAGGA CATCAGTGGC AAGACCCAGA TCCAGTCTGT AGAACCATAT 
ACCAAGCAGC AGCTGAACAA CATGTCATTT GCTGAAATCA TCATGGGCTA TAAGATCATG 
GACGCTACCA ACATCCTGGT ATCCCCACTG GTCTACCTCT ACCCTGACAT TCCCAAGGAG 
GAGGCATTCG GAAAGTATTG TCGCCCCGAG AGCCAGGAGC ACCCTGAAGC TGACCCAGGT 
AGTGCTGCCC CTTACCTGAA GACCAAGTTC ATCTGTGTGA CACCATTCAT TGATGCAGTT 
TGGAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Stat3 ( XM_006247259.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006247321.1 Rattus norvegicus signal transducer and activator of transcription 3 (Stat3), transcript variant X3, mRNA.

Price & Availability↑

CloneID	ORa33649
Clone ID Related Accession (Same CDS sequence)	XM_006247259.3
Accession Version	XM_006247259.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2166bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	signal transducer and activator of transcription 3 isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005109.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006247259.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTCAGT GGAACCAGCT CCAGCAGCTG GACACGCGCT ACCTGGAGCA GCTTCATCAG 
CTGTACAGCG ATAGCTTCCC CATGGAGCTG CGGCAGTTCC TGGCGCCTTG GATTGAGAGC 
CAAGATTGGG CATATGCAGC CAGCAAAGAG TCACACGCCA CTCTGGTGTT TCATAACCTC 
TTGGGCGAGA TCGACCAGCA GTATAGCCGA TTCCTGCAGG AGTCCAATGT CCTCTATCAG 
CACAACCTGC GAAGAATCAA GCAGTTCCTG CAGAGCAGGT ATCTTGAGAA GCCAATGGAA 
ATTGCCCGGA TTGTGGCCCG ATGCCTGTGG GAAGAGTCTC GCCTCCTCCA GACGGCAGCC 
ACGGCAGCCC AGCAAGGGGG CCAGGCCAAC CACCCCACAG CTGCCGTAGT GACGGAGAAG 
CAGCAGATGC TGGAACAGCA TCTTCAGGAT GTCCGGAAGC GTGTGCAGGA TCTAGAACAG 
AAAATGAAAG TGGTGGAGAA TCTCCAGGAT GACTTTGATT TCAACTATAA AACCCTCAAG 
AGTCAAGGAG ACATGCAGGA TCTGAATGGA AACAACCAGT CTGTGACCAG ACAGAAGATG 
CAGCAGCTGG AGCAGATGCT CACGGCCCTG GACCAGATGC GGAGGAGCAT CGTGAGCGAG 
CTGGCAGGGC TCTTGTCAGC AATGGAGTAC GTGCAGAAGA CACTGACCGA TGAAGAGCTG 
GCTGACTGGA AGAGGCGGCA GCAGATAGCG TGCATCGGAG GCCCTCCCAA CATCTGCCTG 
GACCGTCTGG AAAACTGGAT AACTTCATTA GCAGAATCTC AACTTCAGAC CCGCCAACAA 
ATTAAGAAAC TGGAGGAGCT GCAGCAGAAA GTGTCCTACA AGGGGGACCC TATTGTGCAG 
CACCGGCCAA TGCTGGAGGA GAGGATCGTG GATCTGTTCA GAAACTTAAT GAAGAGTGCC 
TTCGTGGTGG AGCGGCAGCC CTGTATGCCC ATGCACCCGG ACCGGCCCTT AGTCATCAAG 
ACTGGTGTCC AGTTTACCAC AAAAGTCAGG TTGCTGGTCA AATTTCCTGA GTTGAATTAT 
CAGCTTAAAA TTAAAGTGTG CATTGATAAG GACTCTGGGG ATGTTGCTGC CCTCAGAGGG 
TCTCGGAAAT TTAACATTCT GGGCACGAAC ACAAAGGTGA TGAACATGGA GGAGTCCAAC 
AACGGCAGCC TGTCTGCAGA GTTCAAGCAC CTGACCCTGA GGGAGCAGAG ATGTGGGAAT 
GGGGGCCGTG CCAATTGTGA TGCCTCCTTG ATTGTCACTG AGGAGCTGCA CCTGATCACC 
TTTGAGACAG AGGTGTACCA CCAAGGTCTC AAGATCGACC TAGAGACCCA CTCCTTGCCA 
GTCGTGGTGA TCTCCAACAT CTGTCAGATG CCTAATGCTT GGGCATCAAT CCTGTGGTAT 
AACATGCTGA CCAATAACCC CAAGAACGTG AACTTCTTCA CTAAGCCTCC GATTGGAACC 
TGGGACCAAG TGGCCGAGGT GCTGAGCTGG CAGTTCTCGT CCACCACCAA GCGAGGGCTG 
AGCATCGAGC AGCTGACCAC GCTGGCCGAG AAGCTCTTAG GGCCTGGTGT GAACTACTCA 
GGGTGTCAGA TCACATGGGC TAAGTTTTGC AAAGAAAACA TGGCCGGCAA GGGCTTCTCG 
TTCTGGGTCT GGCTAGACAA TATCATCGAC CTTGTGAAAA AGTATATCTT GGCCCTTTGG 
AATGAAGGGT ACATCATGGG TTTCATCAGC AAGGAGCGGG AGAGGGCCAT CCTAAGCACA 
AAGCCCCCGG GCACCTTCCT GCTGCGGTTC AGTGAGAGCA GCAAGGAAGG AGGGGTCACT 
TTCACTTGGG TGGAAAAGGA CATCAGTGGC AAGACCCAGA TCCAGTCTGT AGAACCATAT 
ACCAAGCAGC AGCTGAACAA CATGTCATTT GCTGAAATCA TCATGGGCTA TAAGATCATG 
GACGCTACCA ACATCCTGGT ATCCCCACTG GTCTACCTCT ACCCTGACAT TCCCAAGGAG 
GAGGCATTCG GAAAGTATTG TCGCCCCGAG AGCCAGGAGC ACCCTGAAGC TGACCCAGGT 
GCTGCCCCTT ACCTGAAGAC CAAGTTCATC TGTGTGACAC CATTCATTGA TGCAGTTTGG 
AAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006247321.1
CDS	237..2402
Translation	MAQWNQLQQLDTRYLEQLHQLYSDSFPMELRQFLAPWIESQDWAYAASKESHATLVFHNLLGEIDQQYSRFLQESNVLYQHNLRRIKQFLQSRYLEKPMEIARIVARCLWEESRLLQTAATAAQQGGQANHPTAAVVTEKQQMLEQHLQDVRKRVQDLEQKMKVVENLQDDFDFNYKTLKSQGDMQDLNGNNQSVTRQKMQQLEQMLTALDQMRRSIVSELAGLLSAMEYVQKTLTDEELADWKRRQQIACIGGPPNICLDRLENWITSLAESQLQTRQQIKKLEELQQKVSYKGDPIVQHRPMLEERIVDLFRNLMKSAFVVERQPCMPMHPDRPLVIKTGVQFTTKVRLLVKFPELNYQLKIKVCIDKDSGDVAALRGSRKFNILGTNTKVMNMEESNNGSLSAEFKHLTLREQRCGNGGRANCDASLIVTEELHLITFETEVYHQGLKIDLETHSLPVVVISNICQMPNAWASILWYNMLTNNPKNVNFFTKPPIGTWDQVAEVLSWQFSSTTKRGLSIEQLTTLAEKLLGPGVNYSGCQITWAKFCKENMAGKGFSFWVWLDNIIDLVKKYILALWNEGYIMGFISKERERAILSTKPPGTFLLRFSESSKEGGVTFTWVEKDISGKTQIQSVEPYTKQQLNNMSFAEIIMGYKIMDATNILVSPLVYLYPDIPKEEAFGKYCRPESQEHPEADPGAAPYLKTKFICVTPFIDAVWK

Target ORF information:

RefSeq Version	XM_006247259.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus signal transducer and activator of transcription 3 (Stat3), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006247259.3

ORF Insert Sequence:

ATGGCTCAGT GGAACCAGCT CCAGCAGCTG GACACGCGCT ACCTGGAGCA GCTTCATCAG 
CTGTACAGCG ATAGCTTCCC CATGGAGCTG CGGCAGTTCC TGGCGCCTTG GATTGAGAGC 
CAAGATTGGG CATATGCAGC CAGCAAAGAG TCACACGCCA CTCTGGTGTT TCATAACCTC 
TTGGGCGAGA TCGACCAGCA GTATAGCCGA TTCCTGCAGG AGTCCAATGT CCTCTATCAG 
CACAACCTGC GAAGAATCAA GCAGTTCCTG CAGAGCAGGT ATCTTGAGAA GCCAATGGAA 
ATTGCCCGGA TTGTGGCCCG ATGCCTGTGG GAAGAGTCTC GCCTCCTCCA GACGGCAGCC 
ACGGCAGCCC AGCAAGGGGG CCAGGCCAAC CACCCCACAG CTGCCGTAGT GACGGAGAAG 
CAGCAGATGC TGGAACAGCA TCTTCAGGAT GTCCGGAAGC GTGTGCAGGA TCTAGAACAG 
AAAATGAAAG TGGTGGAGAA TCTCCAGGAT GACTTTGATT TCAACTATAA AACCCTCAAG 
AGTCAAGGAG ACATGCAGGA TCTGAATGGA AACAACCAGT CTGTGACCAG ACAGAAGATG 
CAGCAGCTGG AGCAGATGCT CACGGCCCTG GACCAGATGC GGAGGAGCAT CGTGAGCGAG 
CTGGCAGGGC TCTTGTCAGC AATGGAGTAC GTGCAGAAGA CACTGACCGA TGAAGAGCTG 
GCTGACTGGA AGAGGCGGCA GCAGATAGCG TGCATCGGAG GCCCTCCCAA CATCTGCCTG 
GACCGTCTGG AAAACTGGAT AACTTCATTA GCAGAATCTC AACTTCAGAC CCGCCAACAA 
ATTAAGAAAC TGGAGGAGCT GCAGCAGAAA GTGTCCTACA AGGGGGACCC TATTGTGCAG 
CACCGGCCAA TGCTGGAGGA GAGGATCGTG GATCTGTTCA GAAACTTAAT GAAGAGTGCC 
TTCGTGGTGG AGCGGCAGCC CTGTATGCCC ATGCACCCGG ACCGGCCCTT AGTCATCAAG 
ACTGGTGTCC AGTTTACCAC AAAAGTCAGG TTGCTGGTCA AATTTCCTGA GTTGAATTAT 
CAGCTTAAAA TTAAAGTGTG CATTGATAAG GACTCTGGGG ATGTTGCTGC CCTCAGAGGG 
TCTCGGAAAT TTAACATTCT GGGCACGAAC ACAAAGGTGA TGAACATGGA GGAGTCCAAC 
AACGGCAGCC TGTCTGCAGA GTTCAAGCAC CTGACCCTGA GGGAGCAGAG ATGTGGGAAT 
GGGGGCCGTG CCAATTGTGA TGCCTCCTTG ATTGTCACTG AGGAGCTGCA CCTGATCACC 
TTTGAGACAG AGGTGTACCA CCAAGGTCTC AAGATCGACC TAGAGACCCA CTCCTTGCCA 
GTCGTGGTGA TCTCCAACAT CTGTCAGATG CCTAATGCTT GGGCATCAAT CCTGTGGTAT 
AACATGCTGA CCAATAACCC CAAGAACGTG AACTTCTTCA CTAAGCCTCC GATTGGAACC 
TGGGACCAAG TGGCCGAGGT GCTGAGCTGG CAGTTCTCGT CCACCACCAA GCGAGGGCTG 
AGCATCGAGC AGCTGACCAC GCTGGCCGAG AAGCTCTTAG GGCCTGGTGT GAACTACTCA 
GGGTGTCAGA TCACATGGGC TAAGTTTTGC AAAGAAAACA TGGCCGGCAA GGGCTTCTCG 
TTCTGGGTCT GGCTAGACAA TATCATCGAC CTTGTGAAAA AGTATATCTT GGCCCTTTGG 
AATGAAGGGT ACATCATGGG TTTCATCAGC AAGGAGCGGG AGAGGGCCAT CCTAAGCACA 
AAGCCCCCGG GCACCTTCCT GCTGCGGTTC AGTGAGAGCA GCAAGGAAGG AGGGGTCACT 
TTCACTTGGG TGGAAAAGGA CATCAGTGGC AAGACCCAGA TCCAGTCTGT AGAACCATAT 
ACCAAGCAGC AGCTGAACAA CATGTCATTT GCTGAAATCA TCATGGGCTA TAAGATCATG 
GACGCTACCA ACATCCTGGT ATCCCCACTG GTCTACCTCT ACCCTGACAT TCCCAAGGAG 
GAGGCATTCG GAAAGTATTG TCGCCCCGAG AGCCAGGAGC ACCCTGAAGC TGACCCAGGT 
GCTGCCCCTT ACCTGAAGAC CAAGTTCATC TGTGTGACAC CATTCATTGA TGCAGTTTGG 
AAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Gene-based anchoring of the rat genetic linkage and cytogenetic maps: new regional localizations, orientation of the linkage groups, and insights into mammalian chromosome evolution.
Mammalian genome : official journal of the International Mammalian Genome Society9(9)721-34(1998 Sep)
Szpirer C,Szpirer J,Van Vooren P,Tissir F,Simon JS,Koike G,Jacob HJ,Lander ES,Helou K,Klinga-Levan K,Levan G

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Stat3 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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