Ptpn7 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Ptpn7
Entrez Gene ID	246781
Full Name	protein tyrosine phosphatase, non-receptor type 7
Synonyms	Heptp,Lcptp
General protein information	Preferred Names protein tyrosine phosphatase, non-receptor type 7 Names tyrosine-protein phosphatase non-receptor type 7 hematopoietic protein-tyrosine phosphatase protein-tyrosine phosphatase LC-PTP
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 13 Map Location: 13q13
Summary	tyrosine phosphatase found in T cells, B cells and mast cells [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_006249821.3	XP_006249883.1	tyrosine-protein phosphatase non-receptor type 7 isoform X2
NM_145683.1	NP_663716.1	tyrosine-protein phosphatase non-receptor type 7
XM_006249820.3	XP_006249882.1	tyrosine-protein phosphatase non-receptor type 7 isoform X1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	PTPN7	XP_001140385.2
Mus musculus (house mouse)	Ptpn7	NP_796055.1
Rattus norvegicus (Norway rat)	Ptpn7	NP_663716.1
Gallus gallus (chicken)	PTPN7	XP_004934878.1
	PTPN7	XP_001106613.1
Bos taurus (cattle)	PTPN7	NP_001035666.1
Homo sapiens (human)	PTPN7	NP_002823.3
Canis lupus familiaris (dog)	PTPN7	XP_005622245.1

Gene Ontology
Bibliography

Related articles in PubMed

Haematopoietic protein tyrosine phosphatase (HePTP) phosphorylation by cAMP-dependent protein kinase in T-cells: dynamics and subcellular location.
Nika K, Hyunh H, Williams S, Paul S, Bottini N, Task?n K, Lombroso PJ, Mustelin T
The Biochemical journal378(Pt 2)335-42(2004 Mar)

Hematopoietic protein tyrosine phosphatase suppresses extracellular stimulus-regulated kinase activation.
Gronda M, Arab S, Iafrate B, Suzuki H, Zanke BW
Molecular and cellular biology21(20)6851-8(2001 Oct)

Subcellular localization of intracellular protein tyrosine phosphatases in T cells.
Gj?rloff-Wingren A, Saxena M, Han S, Wang X, Alonso A, Renedo M, Oh P, Williams S, Schnitzer J, Mustelin T
European journal of immunology30(8)2412-21(2000 Aug)

Aggregation of IgE receptors in rat basophilic leukemia 2H3 cells induces tyrosine phosphorylation of the cytosolic protein-tyrosine phosphatase HePTP.
Swieter M, Berenstein EH, Swaim WD, Siraganian RP
The Journal of biological chemistry270(37)21902-6(1995 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Ptpn7 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ptpn7 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa02626	NM_145683.1 Latest version!	Rattus norvegicus protein tyrosine phosphatase, non-receptor type 7 (Ptpn7), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
ORa02626	XM_006249821.3 Latest version!	Rattus norvegicus protein tyrosine phosphatase, non-receptor type 7 (Ptpn7), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
ORa35336	XM_006249820.3 Latest version!	Rattus norvegicus protein tyrosine phosphatase, non-receptor type 7 (Ptpn7), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Ptpn7 ( NM_145683.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_663716.1 Rattus norvegicus protein tyrosine phosphatase, non-receptor type 7 (Ptpn7), mRNA.

Price & Availability↑

CloneID	ORa02626
Clone ID Related Accession (Same CDS sequence)	XM_006249821.3 , NM_145683.1
Accession Version	NM_145683.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1080bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-25
Organism	Rattus norvegicus(Norway rat)
Product	tyrosine-protein phosphatase non-receptor type 7
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from U28356.1. ##Evidence-Data-START## Transcript exon combination :: U28356.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2689594, SAMEA2689599 [ECO:0000348] ##Evidence-Data-END##

ATGGTCCAGG CCTGTGAGGG GCGCTCCAGA GCACAGCTGC CGACCTTGTC TTTGGGGGCA 
GACATGACTC AGCCTCCACC CGCCAAAGCT CCAGCCAAGA AGCATGTGCG GCTGCAGGAG 
AGAAGGGGCT CCAGTGTGGC TCTGATGCTG GATGTGCGGT CACTGGGCAC TGTCGAGCCC 
ATCTGCTCAG TGAACACACC CCGTGAAGTC ACCCTGCACT TCCTGCGCAC AGCCGGGCAC 
CCCCTTACAC GCTGGACTCT ACAGCACCAG CCTCCCAGCC CCAAGCAGCT AGAAGAGGAA 
TTCTTGAAGA TCCCCTCAAA CTTTGTCAAC CCTGAAGACC TGGATATCCC TGGCCATGCC 
TCCAAAGACC GATACAAGAC CATCTTGCCA AATCCCCAGA GCCGTGTCTG TCTTGGCCGG 
GCACACAGCC AGGAGGACAG CGACTACATC AATGCCAATT ACATCCGGGG CTATGATGGA 
AAGGAGAAGG TCTACATTGC TACCCAGGGC CCCATGCCCA ACACTGTAGC AGACTTCTGG 
GAGATGGTGT GGCAGGAAGA TGTATCCCTC ATTGTCATGC TCACCCAGCT CCGAGAGGGC 
AAGGAGAAAT GTGTACACTA CTGGCCCACA GAAGAGGAAG CCTATGGGCC CTTCCAGATC 
CGCATCCAGG GCATGAAAGA GCACCCAGAA TATACTGTGA GGCACCTCAC CATTCAGCAC 
CAACAGGAAT GCCGGTCAGT GAAACACATC CTCTTCTCAG CCTGGCCAGA CCACCAGACG 
CCAGAATCAG CCGGGCCCCT GCTGCGCCTG GTGGCTGAGG TGGAGACCCC AGAGACAGCT 
GCCAACTCCG GGCCTATAGT GGTCCACTGC AGCGCAGGGA TCGGTCGGAC AGGCTGCTTC 
ATCGCCACCC GAATCGGCTG CCAGCAGCTG AAGGCCCGAG GGGAGGTGGA CATTCTGGGC 
ATTGTGTGCC AACTTCGCCT AGACAGAGGA GGCATGATCC AGACGGCGGA GCAGTACCAG 
TTCCTACACC ACACTTTGGC CCTGTATGCA GCCCAGCTGC CCCCGGAGAC CGACCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_663716.1
CDS	107..1186
Translation	MVQACEGRSRAQLPTLSLGADMTQPPPAKAPAKKHVRLQERRGSSVALMLDVRSLGTVEPICSVNTPREVTLHFLRTAGHPLTRWTLQHQPPSPKQLEEEFLKIPSNFVNPEDLDIPGHASKDRYKTILPNPQSRVCLGRAHSQEDSDYINANYIRGYDGKEKVYIATQGPMPNTVADFWEMVWQEDVSLIVMLTQLREGKEKCVHYWPTEEEAYGPFQIRIQGMKEHPEYTVRHLTIQHQQECRSVKHILFSAWPDHQTPESAGPLLRLVAEVETPETAANSGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAAQLPPETDP

Target ORF information:

RefSeq Version	NM_145683.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus protein tyrosine phosphatase, non-receptor type 7 (Ptpn7), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_145683.1

ORF Insert Sequence:

ATGGTCCAGG CCTGTGAGGG GCGCTCCAGA GCACAGCTGC CGACCTTGTC TTTGGGGGCA 
GACATGACTC AGCCTCCACC CGCCAAAGCT CCAGCCAAGA AGCATGTGCG GCTGCAGGAG 
AGAAGGGGCT CCAGTGTGGC TCTGATGCTG GATGTGCGGT CACTGGGCAC TGTCGAGCCC 
ATCTGCTCAG TGAACACACC CCGTGAAGTC ACCCTGCACT TCCTGCGCAC AGCCGGGCAC 
CCCCTTACAC GCTGGACTCT ACAGCACCAG CCTCCCAGCC CCAAGCAGCT AGAAGAGGAA 
TTCTTGAAGA TCCCCTCAAA CTTTGTCAAC CCTGAAGACC TGGATATCCC TGGCCATGCC 
TCCAAAGACC GATACAAGAC CATCTTGCCA AATCCCCAGA GCCGTGTCTG TCTTGGCCGG 
GCACACAGCC AGGAGGACAG CGACTACATC AATGCCAATT ACATCCGGGG CTATGATGGA 
AAGGAGAAGG TCTACATTGC TACCCAGGGC CCCATGCCCA ACACTGTAGC AGACTTCTGG 
GAGATGGTGT GGCAGGAAGA TGTATCCCTC ATTGTCATGC TCACCCAGCT CCGAGAGGGC 
AAGGAGAAAT GTGTACACTA CTGGCCCACA GAAGAGGAAG CCTATGGGCC CTTCCAGATC 
CGCATCCAGG GCATGAAAGA GCACCCAGAA TATACTGTGA GGCACCTCAC CATTCAGCAC 
CAACAGGAAT GCCGGTCAGT GAAACACATC CTCTTCTCAG CCTGGCCAGA CCACCAGACG 
CCAGAATCAG CCGGGCCCCT GCTGCGCCTG GTGGCTGAGG TGGAGACCCC AGAGACAGCT 
GCCAACTCCG GGCCTATAGT GGTCCACTGC AGCGCAGGGA TCGGTCGGAC AGGCTGCTTC 
ATCGCCACCC GAATCGGCTG CCAGCAGCTG AAGGCCCGAG GGGAGGTGGA CATTCTGGGC 
ATTGTGTGCC AACTTCGCCT AGACAGAGGA GGCATGATCC AGACGGCGGA GCAGTACCAG 
TTCCTACACC ACACTTTGGC CCTGTATGCA GCCCAGCTGC CCCCGGAGAC CGACCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ptpn7 ( XM_006249821.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006249883.1 Rattus norvegicus protein tyrosine phosphatase, non-receptor type 7 (Ptpn7), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa02626
Clone ID Related Accession (Same CDS sequence)	XM_006249821.3 , NM_145683.1
Accession Version	XM_006249821.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1080bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	tyrosine-protein phosphatase non-receptor type 7 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005112.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006249821.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTCCAGG CCTGTGAGGG GCGCTCCAGA GCACAGCTGC CGACCTTGTC TTTGGGGGCA 
GACATGACTC AGCCTCCACC CGCCAAAGCT CCAGCCAAGA AGCATGTGCG GCTGCAGGAG 
AGAAGGGGCT CCAGTGTGGC TCTGATGCTG GATGTGCGGT CACTGGGCAC TGTCGAGCCC 
ATCTGCTCAG TGAACACACC CCGTGAAGTC ACCCTGCACT TCCTGCGCAC AGCCGGGCAC 
CCCCTTACAC GCTGGACTCT ACAGCACCAG CCTCCCAGCC CCAAGCAGCT AGAAGAGGAA 
TTCTTGAAGA TCCCCTCAAA CTTTGTCAAC CCTGAAGACC TGGATATCCC TGGCCATGCC 
TCCAAAGACC GATACAAGAC CATCTTGCCA AATCCCCAGA GCCGTGTCTG TCTTGGCCGG 
GCACACAGCC AGGAGGACAG CGACTACATC AATGCCAATT ACATCCGGGG CTATGATGGA 
AAGGAGAAGG TCTACATTGC TACCCAGGGC CCCATGCCCA ACACTGTAGC AGACTTCTGG 
GAGATGGTGT GGCAGGAAGA TGTATCCCTC ATTGTCATGC TCACCCAGCT CCGAGAGGGC 
AAGGAGAAAT GTGTACACTA CTGGCCCACA GAAGAGGAAG CCTATGGGCC CTTCCAGATC 
CGCATCCAGG GCATGAAAGA GCACCCAGAA TATACTGTGA GGCACCTCAC CATTCAGCAC 
CAACAGGAAT GCCGGTCAGT GAAACACATC CTCTTCTCAG CCTGGCCAGA CCACCAGACG 
CCAGAATCAG CCGGGCCCCT GCTGCGCCTG GTGGCTGAGG TGGAGACCCC AGAGACAGCT 
GCCAACTCCG GGCCTATAGT GGTCCACTGC AGCGCAGGGA TCGGTCGGAC AGGCTGCTTC 
ATCGCCACCC GAATCGGCTG CCAGCAGCTG AAGGCCCGAG GGGAGGTGGA CATTCTGGGC 
ATTGTGTGCC AACTTCGCCT AGACAGAGGA GGCATGATCC AGACGGCGGA GCAGTACCAG 
TTCCTACACC ACACTTTGGC CCTGTATGCA GCCCAGCTGC CCCCGGAGAC CGACCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006249883.1
CDS	239..1318
Translation	MVQACEGRSRAQLPTLSLGADMTQPPPAKAPAKKHVRLQERRGSSVALMLDVRSLGTVEPICSVNTPREVTLHFLRTAGHPLTRWTLQHQPPSPKQLEEEFLKIPSNFVNPEDLDIPGHASKDRYKTILPNPQSRVCLGRAHSQEDSDYINANYIRGYDGKEKVYIATQGPMPNTVADFWEMVWQEDVSLIVMLTQLREGKEKCVHYWPTEEEAYGPFQIRIQGMKEHPEYTVRHLTIQHQQECRSVKHILFSAWPDHQTPESAGPLLRLVAEVETPETAANSGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAAQLPPETDP

Target ORF information:

RefSeq Version	XM_006249821.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus protein tyrosine phosphatase, non-receptor type 7 (Ptpn7), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006249821.3

ORF Insert Sequence:

ATGGTCCAGG CCTGTGAGGG GCGCTCCAGA GCACAGCTGC CGACCTTGTC TTTGGGGGCA 
GACATGACTC AGCCTCCACC CGCCAAAGCT CCAGCCAAGA AGCATGTGCG GCTGCAGGAG 
AGAAGGGGCT CCAGTGTGGC TCTGATGCTG GATGTGCGGT CACTGGGCAC TGTCGAGCCC 
ATCTGCTCAG TGAACACACC CCGTGAAGTC ACCCTGCACT TCCTGCGCAC AGCCGGGCAC 
CCCCTTACAC GCTGGACTCT ACAGCACCAG CCTCCCAGCC CCAAGCAGCT AGAAGAGGAA 
TTCTTGAAGA TCCCCTCAAA CTTTGTCAAC CCTGAAGACC TGGATATCCC TGGCCATGCC 
TCCAAAGACC GATACAAGAC CATCTTGCCA AATCCCCAGA GCCGTGTCTG TCTTGGCCGG 
GCACACAGCC AGGAGGACAG CGACTACATC AATGCCAATT ACATCCGGGG CTATGATGGA 
AAGGAGAAGG TCTACATTGC TACCCAGGGC CCCATGCCCA ACACTGTAGC AGACTTCTGG 
GAGATGGTGT GGCAGGAAGA TGTATCCCTC ATTGTCATGC TCACCCAGCT CCGAGAGGGC 
AAGGAGAAAT GTGTACACTA CTGGCCCACA GAAGAGGAAG CCTATGGGCC CTTCCAGATC 
CGCATCCAGG GCATGAAAGA GCACCCAGAA TATACTGTGA GGCACCTCAC CATTCAGCAC 
CAACAGGAAT GCCGGTCAGT GAAACACATC CTCTTCTCAG CCTGGCCAGA CCACCAGACG 
CCAGAATCAG CCGGGCCCCT GCTGCGCCTG GTGGCTGAGG TGGAGACCCC AGAGACAGCT 
GCCAACTCCG GGCCTATAGT GGTCCACTGC AGCGCAGGGA TCGGTCGGAC AGGCTGCTTC 
ATCGCCACCC GAATCGGCTG CCAGCAGCTG AAGGCCCGAG GGGAGGTGGA CATTCTGGGC 
ATTGTGTGCC AACTTCGCCT AGACAGAGGA GGCATGATCC AGACGGCGGA GCAGTACCAG 
TTCCTACACC ACACTTTGGC CCTGTATGCA GCCCAGCTGC CCCCGGAGAC CGACCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ptpn7 ( XM_006249820.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006249882.1 Rattus norvegicus protein tyrosine phosphatase, non-receptor type 7 (Ptpn7), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa35336
Clone ID Related Accession (Same CDS sequence)	XM_006249820.3
Accession Version	XM_006249820.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1218bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	tyrosine-protein phosphatase non-receptor type 7 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005112.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006249820.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGAAGGA GGAGGGAGGA AGCACCCCTG GCCTACTGCC CTGGACAGAG ACCCCATGAG 
CCACAACTGA TCTTGGAGCG GAACTGGCAG GCCTCATGGC TGAGTGAGCC TCCCTTGGGC 
CCAGCAACCT ACCCCAGCAT GGTCCAGGCC TGTGAGGGGC GCTCCAGAGC ACAGCTGCCG 
ACCTTGTCTT TGGGGGCAGA CATGACTCAG CCTCCACCCG CCAAAGCTCC AGCCAAGAAG 
CATGTGCGGC TGCAGGAGAG AAGGGGCTCC AGTGTGGCTC TGATGCTGGA TGTGCGGTCA 
CTGGGCACTG TCGAGCCCAT CTGCTCAGTG AACACACCCC GTGAAGTCAC CCTGCACTTC 
CTGCGCACAG CCGGGCACCC CCTTACACGC TGGACTCTAC AGCACCAGCC TCCCAGCCCC 
AAGCAGCTAG AAGAGGAATT CTTGAAGATC CCCTCAAACT TTGTCAACCC TGAAGACCTG 
GATATCCCTG GCCATGCCTC CAAAGACCGA TACAAGACCA TCTTGCCAAA TCCCCAGAGC 
CGTGTCTGTC TTGGCCGGGC ACACAGCCAG GAGGACAGCG ACTACATCAA TGCCAATTAC 
ATCCGGGGCT ATGATGGAAA GGAGAAGGTC TACATTGCTA CCCAGGGCCC CATGCCCAAC 
ACTGTAGCAG ACTTCTGGGA GATGGTGTGG CAGGAAGATG TATCCCTCAT TGTCATGCTC 
ACCCAGCTCC GAGAGGGCAA GGAGAAATGT GTACACTACT GGCCCACAGA AGAGGAAGCC 
TATGGGCCCT TCCAGATCCG CATCCAGGGC ATGAAAGAGC ACCCAGAATA TACTGTGAGG 
CACCTCACCA TTCAGCACCA ACAGGAATGC CGGTCAGTGA AACACATCCT CTTCTCAGCC 
TGGCCAGACC ACCAGACGCC AGAATCAGCC GGGCCCCTGC TGCGCCTGGT GGCTGAGGTG 
GAGACCCCAG AGACAGCTGC CAACTCCGGG CCTATAGTGG TCCACTGCAG CGCAGGGATC 
GGTCGGACAG GCTGCTTCAT CGCCACCCGA ATCGGCTGCC AGCAGCTGAA GGCCCGAGGG 
GAGGTGGACA TTCTGGGCAT TGTGTGCCAA CTTCGCCTAG ACAGAGGAGG CATGATCCAG 
ACGGCGGAGC AGTACCAGTT CCTACACCAC ACTTTGGCCC TGTATGCAGC CCAGCTGCCC 
CCGGAGACCG ACCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006249882.1
CDS	441..1658
Translation	MGRRREEAPLAYCPGQRPHEPQLILERNWQASWLSEPPLGPATYPSMVQACEGRSRAQLPTLSLGADMTQPPPAKAPAKKHVRLQERRGSSVALMLDVRSLGTVEPICSVNTPREVTLHFLRTAGHPLTRWTLQHQPPSPKQLEEEFLKIPSNFVNPEDLDIPGHASKDRYKTILPNPQSRVCLGRAHSQEDSDYINANYIRGYDGKEKVYIATQGPMPNTVADFWEMVWQEDVSLIVMLTQLREGKEKCVHYWPTEEEAYGPFQIRIQGMKEHPEYTVRHLTIQHQQECRSVKHILFSAWPDHQTPESAGPLLRLVAEVETPETAANSGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAAQLPPETDP

Target ORF information:

RefSeq Version	XM_006249820.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus protein tyrosine phosphatase, non-receptor type 7 (Ptpn7), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006249820.3

ORF Insert Sequence:

ATGGGAAGGA GGAGGGAGGA AGCACCCCTG GCCTACTGCC CTGGACAGAG ACCCCATGAG 
CCACAACTGA TCTTGGAGCG GAACTGGCAG GCCTCATGGC TGAGTGAGCC TCCCTTGGGC 
CCAGCAACCT ACCCCAGCAT GGTCCAGGCC TGTGAGGGGC GCTCCAGAGC ACAGCTGCCG 
ACCTTGTCTT TGGGGGCAGA CATGACTCAG CCTCCACCCG CCAAAGCTCC AGCCAAGAAG 
CATGTGCGGC TGCAGGAGAG AAGGGGCTCC AGTGTGGCTC TGATGCTGGA TGTGCGGTCA 
CTGGGCACTG TCGAGCCCAT CTGCTCAGTG AACACACCCC GTGAAGTCAC CCTGCACTTC 
CTGCGCACAG CCGGGCACCC CCTTACACGC TGGACTCTAC AGCACCAGCC TCCCAGCCCC 
AAGCAGCTAG AAGAGGAATT CTTGAAGATC CCCTCAAACT TTGTCAACCC TGAAGACCTG 
GATATCCCTG GCCATGCCTC CAAAGACCGA TACAAGACCA TCTTGCCAAA TCCCCAGAGC 
CGTGTCTGTC TTGGCCGGGC ACACAGCCAG GAGGACAGCG ACTACATCAA TGCCAATTAC 
ATCCGGGGCT ATGATGGAAA GGAGAAGGTC TACATTGCTA CCCAGGGCCC CATGCCCAAC 
ACTGTAGCAG ACTTCTGGGA GATGGTGTGG CAGGAAGATG TATCCCTCAT TGTCATGCTC 
ACCCAGCTCC GAGAGGGCAA GGAGAAATGT GTACACTACT GGCCCACAGA AGAGGAAGCC 
TATGGGCCCT TCCAGATCCG CATCCAGGGC ATGAAAGAGC ACCCAGAATA TACTGTGAGG 
CACCTCACCA TTCAGCACCA ACAGGAATGC CGGTCAGTGA AACACATCCT CTTCTCAGCC 
TGGCCAGACC ACCAGACGCC AGAATCAGCC GGGCCCCTGC TGCGCCTGGT GGCTGAGGTG 
GAGACCCCAG AGACAGCTGC CAACTCCGGG CCTATAGTGG TCCACTGCAG CGCAGGGATC 
GGTCGGACAG GCTGCTTCAT CGCCACCCGA ATCGGCTGCC AGCAGCTGAA GGCCCGAGGG 
GAGGTGGACA TTCTGGGCAT TGTGTGCCAA CTTCGCCTAG ACAGAGGAGG CATGATCCAG 
ACGGCGGAGC AGTACCAGTT CCTACACCAC ACTTTGGCCC TGTATGCAGC CCAGCTGCCC 
CCGGAGACCG ACCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Haematopoietic protein tyrosine phosphatase (HePTP) phosphorylation by cAMP-dependent protein kinase in T-cells: dynamics and subcellular location.
The Biochemical journal378(Pt 2)335-42(2004 Mar)
Nika K,Hyunh H,Williams S,Paul S,Bottini N,Task?n K,Lombroso PJ,Mustelin T

Hematopoietic protein tyrosine phosphatase suppresses extracellular stimulus-regulated kinase activation.
Molecular and cellular biology21(20)6851-8(2001 Oct)
Gronda M,Arab S,Iafrate B,Suzuki H,Zanke BW

Subcellular localization of intracellular protein tyrosine phosphatases in T cells.
European journal of immunology30(8)2412-21(2000 Aug)
Gj?rloff-Wingren A,Saxena M,Han S,Wang X,Alonso A,Renedo M,Oh P,Williams S,Schnitzer J,Mustelin T

Aggregation of IgE receptors in rat basophilic leukemia 2H3 cells induces tyrosine phosphorylation of the cytosolic protein-tyrosine phosphatase HePTP.
The Journal of biological chemistry270(37)21902-6(1995 Sep)
Swieter M,Berenstein EH,Swaim WD,Siraganian RP

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Ptpn7 cDNA ORF clone, Rattus norvegicus(Norway rat)

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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