Cyp2b1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Cyp2b1
Entrez Gene ID	24300
Full Name	cytochrome P450, family 2, subfamily b, polypeptide 1
Synonyms	Cyp2b-1,Cypbe
General protein information	Preferred Names cytochrome P450, family 2, subfamily b, polypeptide 1 Names cytochrome P450 2B1 CYPIIB1 Cytochrome P450, subfamily IIB (phenobarbital-inducible) (b, e) P450-B P450-LM2 P450-PB1 and P450-PB2 P450b cytochrome P450-B cytochrome P450-LM2 cytochrome P450-PB1 cytochrome P450-PB2 cytochrome P450b
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 7 Map Location: 7q33
Summary	phenobarbitol-inducible member of the p450 xenobiotic-inducible superfamily involved in hydroxylation of decanoic and other fatty acids [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_008765492.1	XP_008763714.1	cytochrome P450 2B1 isoform X2
NM_001134844.1	NP_001128316.1	cytochrome P450 2B1 precursor
XM_008765493.1	XP_008763715.1	cytochrome P450 2B1 isoform X3
XM_017594657.1	XP_017450146.1	cytochrome P450 2B1 isoform X1
XM_008765491.1	XP_008763713.1	cytochrome P450 2B1 isoform X1

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Cyp2b10	NP_034129.1
	CYP2B6	NP_001035302.1
Homo sapiens (human)	CYP2B6	NP_000758.1
Rattus norvegicus (Norway rat)	Cyp2b1	NP_001128316.1
Bos taurus (cattle)	CYP2B6	NP_001068641.1
Rattus norvegicus (Norway rat)	Cyp2b2	NP_001185605.1
Pan troglodytes (chimpanzee)	LOC456052	XP_003316405.1
Canis lupus familiaris (dog)	CYP2B6	NP_001006653.1

Gene Ontology
Bibliography

Related articles in PubMed

Bromuconazole-induced hepatotoxicity is accompanied by upregulation of PXR/CYP3A1 and downregulation of CAR/CYP2B1 gene expression.
Abdelhadya DH, El-Magd MA, Elbialy ZI, Saleh AA
Toxicology mechanisms and methods27(7)544-550(2017 Sep)

Impacts of Blast-Induced Traumatic Brain Injury on Expressions of Hepatic Cytochrome P450 1A2, 2B1, 2D1, and 3A2 in Rats.
Ma J, Wang J, Cheng J, Xiao W, Fan K, Gu J, Yu B, Yin G, Wu J, Ren J, Hou J, Jiang Y, Tan Y, Jin W
Cellular and molecular neurobiology37(1)111-120(2017 Jan)

Expression of microRNAs, CYP1A1 and CYP2B1 in the livers and ovaries of female rats treated with DDT and PAHs.
Chanyshev MD, Kosorotikov NI, Titov SE, Kolesnikov NN, Gulyaeva LF
Life sciences103(2)95-100(2014 May)

Clofibric acid induces hepatic CYP 2B1/2 via constitutive androstane receptor not via peroxisome proliferator activated receptor alpha in rat.
Ibrahim ZS, Ahmed MM, El-Shazly SA, Ishizuka M, Fujita S
Bioscience, biotechnology, and biochemistry78(9)1550-9(2014)

Ascorbic acid deficiency decreases hepatic cytochrome P-450, especially CYP2B1/2B2, and simultaneously induces heme oxygenase-1 gene expression in scurvy-prone ODS rats.
Kobayashi M, Hoshinaga Y, Miura N, Tokuda Y, Shigeoka S, Murai A, Horio F
Bioscience, biotechnology, and biochemistry78(6)1060-6(2014)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Blast-induced traumatic brain injury was found to have a significant impact on CYP2B1 expression in liver.
Title: Impacts of Blast-Induced Traumatic Brain Injury on Expressions of Hepatic Cytochrome P450 1A2, 2B1, 2D1, and 3A2 in Rats.

Following chemical induction, both microRNA and CYP2B1 expression is increased in liver and ovaries.
Title: Expression of microRNAs, CYP1A1 and CYP2B1 in the livers and ovaries of female rats treated with DDT and PAHs.

After brain injury, hepatic CYP2B1 may be down-regulated via induction of constitutive androstane receptor (CAR)1 disassociation from thyroid hormone receptors.
Title: Reduction of thyroid hormones triggers down-regulation of hepatic CYP2B through nuclear receptors CAR and TR in a rat model of acute stroke.

The induction of CYP2B by PB or CFA was comparable to nuclear CAR levels. CAR nuclear translocation was induced by CFA in both rat strains
Title: Clofibric acid induces hepatic CYP 2B1/2 via constitutive androstane receptor not via peroxisome proliferator activated receptor alpha in rat.

stimulation of hepatic heme oxygenase-1 expression by ascorbic acid deficiency caused the decrease in CYP content in liver
Title: Ascorbic acid deficiency decreases hepatic cytochrome P-450, especially CYP2B1/2B2, and simultaneously induces heme oxygenase-1 gene expression in scurvy-prone ODS rats.

The following Cyp2b1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cyp2b1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa12633	NM_001134844.1 Latest version!	Rattus norvegicus cytochrome P450, family 2, subfamily b, polypeptide 1 (Cyp2b1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
ORa12633	XM_008765492.1 Latest version!	Rattus norvegicus cytochrome P450, family 2, subfamily b, polypeptide 1 (Cyp2b1), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
ORa30380	XM_017594657.1 Latest version!	Rattus norvegicus cytochrome P450, family 2, subfamily b, polypeptide 1 (Cyp2b1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
ORa30380	XM_008765491.1 Latest version!	Rattus norvegicus cytochrome P450, family 2, subfamily b, polypeptide 1 (Cyp2b1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
ORa42885	XM_008765493.1 Latest version!	Rattus norvegicus cytochrome P450, family 2, subfamily b, polypeptide 1 (Cyp2b1), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Cyp2b1 ( NM_001134844.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001128316.1 Rattus norvegicus cytochrome P450, family 2, subfamily b, polypeptide 1 (Cyp2b1), mRNA.

Price & Availability↑

CloneID	ORa12633
Clone ID Related Accession (Same CDS sequence)	XM_008765492.1 , NM_001134844.1
Accession Version	NM_001134844.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1476bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-03
Organism	Rattus norvegicus(Norway rat)
Product	cytochrome P450 2B1 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC166502.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC166502.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2689599, SAMEA2689602 [ECO:0000348] ##Evidence-Data-END##

ATGGAGCCCA GTATCTTGCT CCTCCTTGCT CTCCTCGTGG GCTTCTTGTT ACTCTTAGTC 
AGGGGACACC CAAAGTCCCG TGGCAACTTC CCACCAGGAC CTCGTCCCCT TCCCCTCTTG 
GGGAACCTCC TGCAGTTGGA CAGAGGGGGC CTCCTCAATT CCTTCATGCA GCTTCGAGAA 
AAATATGGAG ATGTGTTCAC AGTACACCTG GGACCAAGGC CTGTGGTCAT GCTATGTGGG 
ACAGACACCA TAAAGGAGGC TCTGGTGGGC CAAGCTGAGG ATTTCTCTGG TCGGGGAACA 
ATCGCTGTGA TTGAGCCAAT CTTCAAGGAA TATGGTGTGA TCTTTGCCAA TGGGGAACGC 
TGGAAGGCCC TTCGGCGATT CTCTCTGGCT ACCATGAGAG ACTTTGGGAT GGGAAAGAGG 
AGTGTGGAAG AACGGATTCA GGAGGAAGCC CAATGTTTGG TGGAGGAACT GCGGAAATCC 
CAGGGAGCCC CACTGGATCC CACCTTCCTC TTCCAGTGCA TCACAGCCAA CATCATCTGC 
TCCATTGTGT TTGGAGAGCG CTTTGACTAC ACAGACCGCC AGTTCCTGCG CCTGTTGGAG 
CTGTTCTACC GGACCTTTTC CCTCCTAAGT TCATTCTCCA GCCAGGTGTT TGAGTTCTTC 
TCTGGGTTCC TGAAATACTT TCCTGGTGCC CACAGACAAA TCTCCAAAAA CCTCCAGGAA 
ATCCTCGATT ACATTGGCCA TATTGTGGAG AAGCACAGGG CCACCTTAGA CCCAAGCGCT 
CCACGAGACT TCATCGACAC TTACCTTCTG CGCATGGAGA AGGAGAAGTC GAACCACCAC 
ACAGTGTTCC ATCATGAGAA CCTCATGATC TCCCTGCTCT CTCTCTTCTT TGCTGGCACT 
GAGACCAGCA GCACCACACT CCGCTATGGT TTCCTGCTGA TGCTCAAGTA CCCCCATGTC 
GCAGAGAAAG TCCAAAAGGA GATTGATCAG GTGATCGGCT CACACCGGCT ACCAACCCTT 
GATGACCGCA GTAAAATGCC ATACACTGAT GCAGTTATCC ATGAGATTCA GAGGTTTTCA 
GATCTTGTCC CTATTGGAGT ACCACACAGA GTCACCAAAG ACACCATGTT CCGAGGGTAC 
CTGCTTCCCA AGAACACTGA AGTGTACCCC ATCCTGAGTT CAGCTCTCCA TGACCCACAG 
TACTTTGACC ACCCAGACAG CTTCAATCCT GAACACTTCC TGGATGCCAA TGGGGCACTG 
AAAAAGAGTG AAGCTTTCAT GCCCTTCTCC ACAGGAAAGC GCATTTGTCT TGGCGAAGGC 
ATTGCCCGAA ATGAATTGTT CCTCTTCTTC ACCACCATCC TCCAGAACTT CTCTGTGTCA 
AGCCATTTGG CTCCCAAGGA CATTGACCTC ACGCCCAAGG AGAGTGGCAT TGGAAAAATA 
CCTCCAACGT ACCAGATCTG CTTCTCAGCT CGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001128316.1
CDS	18..1493
Translation	MEPSILLLLALLVGFLLLLVRGHPKSRGNFPPGPRPLPLLGNLLQLDRGGLLNSFMQLREKYGDVFTVHLGPRPVVMLCGTDTIKEALVGQAEDFSGRGTIAVIEPIFKEYGVIFANGERWKALRRFSLATMRDFGMGKRSVEERIQEEAQCLVEELRKSQGAPLDPTFLFQCITANIICSIVFGERFDYTDRQFLRLLELFYRTFSLLSSFSSQVFEFFSGFLKYFPGAHRQISKNLQEILDYIGHIVEKHRATLDPSAPRDFIDTYLLRMEKEKSNHHTVFHHENLMISLLSLFFAGTETSSTTLRYGFLLMLKYPHVAEKVQKEIDQVIGSHRLPTLDDRSKMPYTDAVIHEIQRFSDLVPIGVPHRVTKDTMFRGYLLPKNTEVYPILSSALHDPQYFDHPDSFNPEHFLDANGALKKSEAFMPFSTGKRICLGEGIARNELFLFFTTILQNFSVSSHLAPKDIDLTPKESGIGKIPPTYQICFSAR

Target ORF information:

RefSeq Version	NM_001134844.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus cytochrome P450, family 2, subfamily b, polypeptide 1 (Cyp2b1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001134844.1

ORF Insert Sequence:

ATGGAGCCCA GTATCTTGCT CCTCCTTGCT CTCCTCGTGG GCTTCTTGTT ACTCTTAGTC 
AGGGGACACC CAAAGTCCCG TGGCAACTTC CCACCAGGAC CTCGTCCCCT TCCCCTCTTG 
GGGAACCTCC TGCAGTTGGA CAGAGGGGGC CTCCTCAATT CCTTCATGCA GCTTCGAGAA 
AAATATGGAG ATGTGTTCAC AGTACACCTG GGACCAAGGC CTGTGGTCAT GCTATGTGGG 
ACAGACACCA TAAAGGAGGC TCTGGTGGGC CAAGCTGAGG ATTTCTCTGG TCGGGGAACA 
ATCGCTGTGA TTGAGCCAAT CTTCAAGGAA TATGGTGTGA TCTTTGCCAA TGGGGAACGC 
TGGAAGGCCC TTCGGCGATT CTCTCTGGCT ACCATGAGAG ACTTTGGGAT GGGAAAGAGG 
AGTGTGGAAG AACGGATTCA GGAGGAAGCC CAATGTTTGG TGGAGGAACT GCGGAAATCC 
CAGGGAGCCC CACTGGATCC CACCTTCCTC TTCCAGTGCA TCACAGCCAA CATCATCTGC 
TCCATTGTGT TTGGAGAGCG CTTTGACTAC ACAGACCGCC AGTTCCTGCG CCTGTTGGAG 
CTGTTCTACC GGACCTTTTC CCTCCTAAGT TCATTCTCCA GCCAGGTGTT TGAGTTCTTC 
TCTGGGTTCC TGAAATACTT TCCTGGTGCC CACAGACAAA TCTCCAAAAA CCTCCAGGAA 
ATCCTCGATT ACATTGGCCA TATTGTGGAG AAGCACAGGG CCACCTTAGA CCCAAGCGCT 
CCACGAGACT TCATCGACAC TTACCTTCTG CGCATGGAGA AGGAGAAGTC GAACCACCAC 
ACAGTGTTCC ATCATGAGAA CCTCATGATC TCCCTGCTCT CTCTCTTCTT TGCTGGCACT 
GAGACCAGCA GCACCACACT CCGCTATGGT TTCCTGCTGA TGCTCAAGTA CCCCCATGTC 
GCAGAGAAAG TCCAAAAGGA GATTGATCAG GTGATCGGCT CACACCGGCT ACCAACCCTT 
GATGACCGCA GTAAAATGCC ATACACTGAT GCAGTTATCC ATGAGATTCA GAGGTTTTCA 
GATCTTGTCC CTATTGGAGT ACCACACAGA GTCACCAAAG ACACCATGTT CCGAGGGTAC 
CTGCTTCCCA AGAACACTGA AGTGTACCCC ATCCTGAGTT CAGCTCTCCA TGACCCACAG 
TACTTTGACC ACCCAGACAG CTTCAATCCT GAACACTTCC TGGATGCCAA TGGGGCACTG 
AAAAAGAGTG AAGCTTTCAT GCCCTTCTCC ACAGGAAAGC GCATTTGTCT TGGCGAAGGC 
ATTGCCCGAA ATGAATTGTT CCTCTTCTTC ACCACCATCC TCCAGAACTT CTCTGTGTCA 
AGCCATTTGG CTCCCAAGGA CATTGACCTC ACGCCCAAGG AGAGTGGCAT TGGAAAAATA 
CCTCCAACGT ACCAGATCTG CTTCTCAGCT CGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cyp2b1 ( XM_008765492.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008763714.1 Rattus norvegicus cytochrome P450, family 2, subfamily b, polypeptide 1 (Cyp2b1), transcript variant X3, mRNA.

Price & Availability↑

CloneID	ORa12633
Clone ID Related Accession (Same CDS sequence)	XM_008765492.1 , NM_001134844.1
Accession Version	XM_008765492.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1476bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	cytochrome P450 2B1 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005106.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGCCCA GTATCTTGCT CCTCCTTGCT CTCCTCGTGG GCTTCTTGTT ACTCTTAGTC 
AGGGGACACC CAAAGTCCCG TGGCAACTTC CCACCAGGAC CTCGTCCCCT TCCCCTCTTG 
GGGAACCTCC TGCAGTTGGA CAGAGGGGGC CTCCTCAATT CCTTCATGCA GCTTCGAGAA 
AAATATGGAG ATGTGTTCAC AGTACACCTG GGACCAAGGC CTGTGGTCAT GCTATGTGGG 
ACAGACACCA TAAAGGAGGC TCTGGTGGGC CAAGCTGAGG ATTTCTCTGG TCGGGGAACA 
ATCGCTGTGA TTGAGCCAAT CTTCAAGGAA TATGGTGTGA TCTTTGCCAA TGGGGAACGC 
TGGAAGGCCC TTCGGCGATT CTCTCTGGCT ACCATGAGAG ACTTTGGGAT GGGAAAGAGG 
AGTGTGGAAG AACGGATTCA GGAGGAAGCC CAATGTTTGG TGGAGGAACT GCGGAAATCC 
CAGGGAGCCC CACTGGATCC CACCTTCCTC TTCCAGTGCA TCACAGCCAA CATCATCTGC 
TCCATTGTGT TTGGAGAGCG CTTTGACTAC ACAGACCGCC AGTTCCTGCG CCTGTTGGAG 
CTGTTCTACC GGACCTTTTC CCTCCTAAGT TCATTCTCCA GCCAGGTGTT TGAGTTCTTC 
TCTGGGTTCC TGAAATACTT TCCTGGTGCC CACAGACAAA TCTCCAAAAA CCTCCAGGAA 
ATCCTCGATT ACATTGGCCA TATTGTGGAG AAGCACAGGG CCACCTTAGA CCCAAGCGCT 
CCACGAGACT TCATCGACAC TTACCTTCTG CGCATGGAGA AGGAGAAGTC GAACCACCAC 
ACAGTGTTCC ATCATGAGAA CCTCATGATC TCCCTGCTCT CTCTCTTCTT TGCTGGCACT 
GAGACCAGCA GCACCACACT CCGCTATGGT TTCCTGCTGA TGCTCAAGTA CCCCCATGTC 
GCAGAGAAAG TCCAAAAGGA GATTGATCAG GTGATCGGCT CACACCGGCT ACCAACCCTT 
GATGACCGCA GTAAAATGCC ATACACTGAT GCAGTTATCC ATGAGATTCA GAGGTTTTCA 
GATCTTGTCC CTATTGGAGT ACCACACAGA GTCACCAAAG ACACCATGTT CCGAGGGTAC 
CTGCTTCCCA AGAACACTGA AGTGTACCCC ATCCTGAGTT CAGCTCTCCA TGACCCACAG 
TACTTTGACC ACCCAGACAG CTTCAATCCT GAACACTTCC TGGATGCCAA TGGGGCACTG 
AAAAAGAGTG AAGCTTTCAT GCCCTTCTCC ACAGGAAAGC GCATTTGTCT TGGCGAAGGC 
ATTGCCCGAA ATGAATTGTT CCTCTTCTTC ACCACCATCC TCCAGAACTT CTCTGTGTCA 
AGCCATTTGG CTCCCAAGGA CATTGACCTC ACGCCCAAGG AGAGTGGCAT TGGAAAAATA 
CCTCCAACGT ACCAGATCTG CTTCTCAGCT CGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008763714.1
CDS	37..1512
Translation	MEPSILLLLALLVGFLLLLVRGHPKSRGNFPPGPRPLPLLGNLLQLDRGGLLNSFMQLREKYGDVFTVHLGPRPVVMLCGTDTIKEALVGQAEDFSGRGTIAVIEPIFKEYGVIFANGERWKALRRFSLATMRDFGMGKRSVEERIQEEAQCLVEELRKSQGAPLDPTFLFQCITANIICSIVFGERFDYTDRQFLRLLELFYRTFSLLSSFSSQVFEFFSGFLKYFPGAHRQISKNLQEILDYIGHIVEKHRATLDPSAPRDFIDTYLLRMEKEKSNHHTVFHHENLMISLLSLFFAGTETSSTTLRYGFLLMLKYPHVAEKVQKEIDQVIGSHRLPTLDDRSKMPYTDAVIHEIQRFSDLVPIGVPHRVTKDTMFRGYLLPKNTEVYPILSSALHDPQYFDHPDSFNPEHFLDANGALKKSEAFMPFSTGKRICLGEGIARNELFLFFTTILQNFSVSSHLAPKDIDLTPKESGIGKIPPTYQICFSAR

Target ORF information:

RefSeq Version	XM_008765492.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus cytochrome P450, family 2, subfamily b, polypeptide 1 (Cyp2b1), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008765492.1

ORF Insert Sequence:

ATGGAGCCCA GTATCTTGCT CCTCCTTGCT CTCCTCGTGG GCTTCTTGTT ACTCTTAGTC 
AGGGGACACC CAAAGTCCCG TGGCAACTTC CCACCAGGAC CTCGTCCCCT TCCCCTCTTG 
GGGAACCTCC TGCAGTTGGA CAGAGGGGGC CTCCTCAATT CCTTCATGCA GCTTCGAGAA 
AAATATGGAG ATGTGTTCAC AGTACACCTG GGACCAAGGC CTGTGGTCAT GCTATGTGGG 
ACAGACACCA TAAAGGAGGC TCTGGTGGGC CAAGCTGAGG ATTTCTCTGG TCGGGGAACA 
ATCGCTGTGA TTGAGCCAAT CTTCAAGGAA TATGGTGTGA TCTTTGCCAA TGGGGAACGC 
TGGAAGGCCC TTCGGCGATT CTCTCTGGCT ACCATGAGAG ACTTTGGGAT GGGAAAGAGG 
AGTGTGGAAG AACGGATTCA GGAGGAAGCC CAATGTTTGG TGGAGGAACT GCGGAAATCC 
CAGGGAGCCC CACTGGATCC CACCTTCCTC TTCCAGTGCA TCACAGCCAA CATCATCTGC 
TCCATTGTGT TTGGAGAGCG CTTTGACTAC ACAGACCGCC AGTTCCTGCG CCTGTTGGAG 
CTGTTCTACC GGACCTTTTC CCTCCTAAGT TCATTCTCCA GCCAGGTGTT TGAGTTCTTC 
TCTGGGTTCC TGAAATACTT TCCTGGTGCC CACAGACAAA TCTCCAAAAA CCTCCAGGAA 
ATCCTCGATT ACATTGGCCA TATTGTGGAG AAGCACAGGG CCACCTTAGA CCCAAGCGCT 
CCACGAGACT TCATCGACAC TTACCTTCTG CGCATGGAGA AGGAGAAGTC GAACCACCAC 
ACAGTGTTCC ATCATGAGAA CCTCATGATC TCCCTGCTCT CTCTCTTCTT TGCTGGCACT 
GAGACCAGCA GCACCACACT CCGCTATGGT TTCCTGCTGA TGCTCAAGTA CCCCCATGTC 
GCAGAGAAAG TCCAAAAGGA GATTGATCAG GTGATCGGCT CACACCGGCT ACCAACCCTT 
GATGACCGCA GTAAAATGCC ATACACTGAT GCAGTTATCC ATGAGATTCA GAGGTTTTCA 
GATCTTGTCC CTATTGGAGT ACCACACAGA GTCACCAAAG ACACCATGTT CCGAGGGTAC 
CTGCTTCCCA AGAACACTGA AGTGTACCCC ATCCTGAGTT CAGCTCTCCA TGACCCACAG 
TACTTTGACC ACCCAGACAG CTTCAATCCT GAACACTTCC TGGATGCCAA TGGGGCACTG 
AAAAAGAGTG AAGCTTTCAT GCCCTTCTCC ACAGGAAAGC GCATTTGTCT TGGCGAAGGC 
ATTGCCCGAA ATGAATTGTT CCTCTTCTTC ACCACCATCC TCCAGAACTT CTCTGTGTCA 
AGCCATTTGG CTCCCAAGGA CATTGACCTC ACGCCCAAGG AGAGTGGCAT TGGAAAAATA 
CCTCCAACGT ACCAGATCTG CTTCTCAGCT CGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cyp2b1 ( XM_017594657.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017450146.1 Rattus norvegicus cytochrome P450, family 2, subfamily b, polypeptide 1 (Cyp2b1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa30380
Clone ID Related Accession (Same CDS sequence)	XM_017594657.1 , XM_008765491.1
Accession Version	XM_017594657.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1500bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	cytochrome P450 2B1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005106.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGCCCA GTATCTTGCT CCTCCTTGCT CTCCTCGTGG GCTTCTTGTT ACTCTTAGTC 
AGGGGACACC CAAAGTCCCG TGGCAACTTC CCACCAGGAC CTCGTCCCCT TCCCCTCTTG 
GGGAACCTCC TGCAGTTGGA CAGAGGGGGC CTCCTCAATT CCTTCATGCA GCTTCGAGAA 
AAATATGGAG ATGTGTTCAC AGTACACCTG GGACCAAGGC CTGTGGTCAT GCTATGTGGG 
ACAGACACCA TAAAGGAGGC TCTGGTGGGC CAAGCTGAGG ATTTCTCTGG TCGGGGAACA 
ATCGCTGTGA TTGAGCCAAT CTTCAAGGAA TATGGTGTGA TCTTTGCCAA TGGGGAACGC 
TGGAAGGCCC TTCGGCGATT CTCTCTGGCT ACCATGAGAG ACTTTGGGAT GGGAAAGAGG 
AGTGTGGAAG AACGGATTCA GGAGGAAGCC CAATGTTTGG TGGAGGAACT GCGGAAATCC 
CAGGGAGCCC CACTGGATCC CACCTTCCTC TTCCAGTGCA TCACAGCCAA CATCATCTGC 
TCCATTGTGT TTGGAGAGCG CTTTGACTAC ACAGACCGCC AGTTCCTGCG CCTGTTGGAG 
CTGTTCTACC GGACCTTTTC CCTCCTAAGT TCATTCTCCA GCCAGGTGTT TGAGTTCTTC 
TCTGGGTTCC TGAAATACTT TCCTGGTGCC CACAGACAAA TCTCCAAAAA CCTCCAGGAA 
ATCCTCGATT ACATTGGCCA TATTGTGGAG AAGCACAGGG CCACCTTAGA CCCAAGCGCT 
CCACGAGACT TCATCGACAC TTACCTTCTG CGCATGGAGA AGGTGAGTCC TGCATGGATG 
AGAGAGGAGA AGTCGAACCA CCACACAGTG TTCCATCATG AGAACCTCAT GATCTCCCTG 
CTCTCTCTCT TCTTTGCTGG CACTGAGACC AGCAGCACCA CACTCCGCTA TGGTTTCCTG 
CTGATGCTCA AGTACCCCCA TGTCGCAGAG AAAGTCCAAA AGGAGATTGA TCAGGTGATC 
GGCTCACACC GGCTACCAAC CCTTGATGAC CGCAGTAAAA TGCCATACAC TGATGCAGTT 
ATCCATGAGA TTCAGAGGTT TTCAGATCTT GTCCCTATTG GAGTACCACA CAGAGTCACC 
AAAGACACCA TGTTCCGAGG GTACCTGCTT CCCAAGAACA CTGAAGTGTA CCCCATCCTG 
AGTTCAGCTC TCCATGACCC ACAGTACTTT GACCACCCAG ACAGCTTCAA TCCTGAACAC 
TTCCTGGATG CCAATGGGGC ACTGAAAAAG AGTGAAGCTT TCATGCCCTT CTCCACAGGA 
AAGCGCATTT GTCTTGGCGA AGGCATTGCC CGAAATGAAT TGTTCCTCTT CTTCACCACC 
ATCCTCCAGA ACTTCTCTGT GTCAAGCCAT TTGGCTCCCA AGGACATTGA CCTCACGCCC 
AAGGAGAGTG GCATTGGAAA AATACCTCCA ACGTACCAGA TCTGCTTCTC AGCTCGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017450146.1
CDS	37..1536
Translation	MEPSILLLLALLVGFLLLLVRGHPKSRGNFPPGPRPLPLLGNLLQLDRGGLLNSFMQLREKYGDVFTVHLGPRPVVMLCGTDTIKEALVGQAEDFSGRGTIAVIEPIFKEYGVIFANGERWKALRRFSLATMRDFGMGKRSVEERIQEEAQCLVEELRKSQGAPLDPTFLFQCITANIICSIVFGERFDYTDRQFLRLLELFYRTFSLLSSFSSQVFEFFSGFLKYFPGAHRQISKNLQEILDYIGHIVEKHRATLDPSAPRDFIDTYLLRMEKVSPAWMREEKSNHHTVFHHENLMISLLSLFFAGTETSSTTLRYGFLLMLKYPHVAEKVQKEIDQVIGSHRLPTLDDRSKMPYTDAVIHEIQRFSDLVPIGVPHRVTKDTMFRGYLLPKNTEVYPILSSALHDPQYFDHPDSFNPEHFLDANGALKKSEAFMPFSTGKRICLGEGIARNELFLFFTTILQNFSVSSHLAPKDIDLTPKESGIGKIPPTYQICFSAR

Target ORF information:

RefSeq Version	XM_017594657.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus cytochrome P450, family 2, subfamily b, polypeptide 1 (Cyp2b1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017594657.1

ORF Insert Sequence:

ATGGAGCCCA GTATCTTGCT CCTCCTTGCT CTCCTCGTGG GCTTCTTGTT ACTCTTAGTC 
AGGGGACACC CAAAGTCCCG TGGCAACTTC CCACCAGGAC CTCGTCCCCT TCCCCTCTTG 
GGGAACCTCC TGCAGTTGGA CAGAGGGGGC CTCCTCAATT CCTTCATGCA GCTTCGAGAA 
AAATATGGAG ATGTGTTCAC AGTACACCTG GGACCAAGGC CTGTGGTCAT GCTATGTGGG 
ACAGACACCA TAAAGGAGGC TCTGGTGGGC CAAGCTGAGG ATTTCTCTGG TCGGGGAACA 
ATCGCTGTGA TTGAGCCAAT CTTCAAGGAA TATGGTGTGA TCTTTGCCAA TGGGGAACGC 
TGGAAGGCCC TTCGGCGATT CTCTCTGGCT ACCATGAGAG ACTTTGGGAT GGGAAAGAGG 
AGTGTGGAAG AACGGATTCA GGAGGAAGCC CAATGTTTGG TGGAGGAACT GCGGAAATCC 
CAGGGAGCCC CACTGGATCC CACCTTCCTC TTCCAGTGCA TCACAGCCAA CATCATCTGC 
TCCATTGTGT TTGGAGAGCG CTTTGACTAC ACAGACCGCC AGTTCCTGCG CCTGTTGGAG 
CTGTTCTACC GGACCTTTTC CCTCCTAAGT TCATTCTCCA GCCAGGTGTT TGAGTTCTTC 
TCTGGGTTCC TGAAATACTT TCCTGGTGCC CACAGACAAA TCTCCAAAAA CCTCCAGGAA 
ATCCTCGATT ACATTGGCCA TATTGTGGAG AAGCACAGGG CCACCTTAGA CCCAAGCGCT 
CCACGAGACT TCATCGACAC TTACCTTCTG CGCATGGAGA AGGTGAGTCC TGCATGGATG 
AGAGAGGAGA AGTCGAACCA CCACACAGTG TTCCATCATG AGAACCTCAT GATCTCCCTG 
CTCTCTCTCT TCTTTGCTGG CACTGAGACC AGCAGCACCA CACTCCGCTA TGGTTTCCTG 
CTGATGCTCA AGTACCCCCA TGTCGCAGAG AAAGTCCAAA AGGAGATTGA TCAGGTGATC 
GGCTCACACC GGCTACCAAC CCTTGATGAC CGCAGTAAAA TGCCATACAC TGATGCAGTT 
ATCCATGAGA TTCAGAGGTT TTCAGATCTT GTCCCTATTG GAGTACCACA CAGAGTCACC 
AAAGACACCA TGTTCCGAGG GTACCTGCTT CCCAAGAACA CTGAAGTGTA CCCCATCCTG 
AGTTCAGCTC TCCATGACCC ACAGTACTTT GACCACCCAG ACAGCTTCAA TCCTGAACAC 
TTCCTGGATG CCAATGGGGC ACTGAAAAAG AGTGAAGCTT TCATGCCCTT CTCCACAGGA 
AAGCGCATTT GTCTTGGCGA AGGCATTGCC CGAAATGAAT TGTTCCTCTT CTTCACCACC 
ATCCTCCAGA ACTTCTCTGT GTCAAGCCAT TTGGCTCCCA AGGACATTGA CCTCACGCCC 
AAGGAGAGTG GCATTGGAAA AATACCTCCA ACGTACCAGA TCTGCTTCTC AGCTCGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cyp2b1 ( XM_008765491.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008763713.1 Rattus norvegicus cytochrome P450, family 2, subfamily b, polypeptide 1 (Cyp2b1), transcript variant X2, mRNA.

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CloneID	ORa30380
Clone ID Related Accession (Same CDS sequence)	XM_017594657.1 , XM_008765491.1
Accession Version	XM_008765491.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1500bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	cytochrome P450 2B1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005106.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGCCCA GTATCTTGCT CCTCCTTGCT CTCCTCGTGG GCTTCTTGTT ACTCTTAGTC 
AGGGGACACC CAAAGTCCCG TGGCAACTTC CCACCAGGAC CTCGTCCCCT TCCCCTCTTG 
GGGAACCTCC TGCAGTTGGA CAGAGGGGGC CTCCTCAATT CCTTCATGCA GCTTCGAGAA 
AAATATGGAG ATGTGTTCAC AGTACACCTG GGACCAAGGC CTGTGGTCAT GCTATGTGGG 
ACAGACACCA TAAAGGAGGC TCTGGTGGGC CAAGCTGAGG ATTTCTCTGG TCGGGGAACA 
ATCGCTGTGA TTGAGCCAAT CTTCAAGGAA TATGGTGTGA TCTTTGCCAA TGGGGAACGC 
TGGAAGGCCC TTCGGCGATT CTCTCTGGCT ACCATGAGAG ACTTTGGGAT GGGAAAGAGG 
AGTGTGGAAG AACGGATTCA GGAGGAAGCC CAATGTTTGG TGGAGGAACT GCGGAAATCC 
CAGGGAGCCC CACTGGATCC CACCTTCCTC TTCCAGTGCA TCACAGCCAA CATCATCTGC 
TCCATTGTGT TTGGAGAGCG CTTTGACTAC ACAGACCGCC AGTTCCTGCG CCTGTTGGAG 
CTGTTCTACC GGACCTTTTC CCTCCTAAGT TCATTCTCCA GCCAGGTGTT TGAGTTCTTC 
TCTGGGTTCC TGAAATACTT TCCTGGTGCC CACAGACAAA TCTCCAAAAA CCTCCAGGAA 
ATCCTCGATT ACATTGGCCA TATTGTGGAG AAGCACAGGG CCACCTTAGA CCCAAGCGCT 
CCACGAGACT TCATCGACAC TTACCTTCTG CGCATGGAGA AGGTGAGTCC TGCATGGATG 
AGAGAGGAGA AGTCGAACCA CCACACAGTG TTCCATCATG AGAACCTCAT GATCTCCCTG 
CTCTCTCTCT TCTTTGCTGG CACTGAGACC AGCAGCACCA CACTCCGCTA TGGTTTCCTG 
CTGATGCTCA AGTACCCCCA TGTCGCAGAG AAAGTCCAAA AGGAGATTGA TCAGGTGATC 
GGCTCACACC GGCTACCAAC CCTTGATGAC CGCAGTAAAA TGCCATACAC TGATGCAGTT 
ATCCATGAGA TTCAGAGGTT TTCAGATCTT GTCCCTATTG GAGTACCACA CAGAGTCACC 
AAAGACACCA TGTTCCGAGG GTACCTGCTT CCCAAGAACA CTGAAGTGTA CCCCATCCTG 
AGTTCAGCTC TCCATGACCC ACAGTACTTT GACCACCCAG ACAGCTTCAA TCCTGAACAC 
TTCCTGGATG CCAATGGGGC ACTGAAAAAG AGTGAAGCTT TCATGCCCTT CTCCACAGGA 
AAGCGCATTT GTCTTGGCGA AGGCATTGCC CGAAATGAAT TGTTCCTCTT CTTCACCACC 
ATCCTCCAGA ACTTCTCTGT GTCAAGCCAT TTGGCTCCCA AGGACATTGA CCTCACGCCC 
AAGGAGAGTG GCATTGGAAA AATACCTCCA ACGTACCAGA TCTGCTTCTC AGCTCGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008763713.1
CDS	37..1536
Translation	MEPSILLLLALLVGFLLLLVRGHPKSRGNFPPGPRPLPLLGNLLQLDRGGLLNSFMQLREKYGDVFTVHLGPRPVVMLCGTDTIKEALVGQAEDFSGRGTIAVIEPIFKEYGVIFANGERWKALRRFSLATMRDFGMGKRSVEERIQEEAQCLVEELRKSQGAPLDPTFLFQCITANIICSIVFGERFDYTDRQFLRLLELFYRTFSLLSSFSSQVFEFFSGFLKYFPGAHRQISKNLQEILDYIGHIVEKHRATLDPSAPRDFIDTYLLRMEKVSPAWMREEKSNHHTVFHHENLMISLLSLFFAGTETSSTTLRYGFLLMLKYPHVAEKVQKEIDQVIGSHRLPTLDDRSKMPYTDAVIHEIQRFSDLVPIGVPHRVTKDTMFRGYLLPKNTEVYPILSSALHDPQYFDHPDSFNPEHFLDANGALKKSEAFMPFSTGKRICLGEGIARNELFLFFTTILQNFSVSSHLAPKDIDLTPKESGIGKIPPTYQICFSAR

Target ORF information:

RefSeq Version	XM_008765491.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus cytochrome P450, family 2, subfamily b, polypeptide 1 (Cyp2b1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008765491.1

ORF Insert Sequence:

ATGGAGCCCA GTATCTTGCT CCTCCTTGCT CTCCTCGTGG GCTTCTTGTT ACTCTTAGTC 
AGGGGACACC CAAAGTCCCG TGGCAACTTC CCACCAGGAC CTCGTCCCCT TCCCCTCTTG 
GGGAACCTCC TGCAGTTGGA CAGAGGGGGC CTCCTCAATT CCTTCATGCA GCTTCGAGAA 
AAATATGGAG ATGTGTTCAC AGTACACCTG GGACCAAGGC CTGTGGTCAT GCTATGTGGG 
ACAGACACCA TAAAGGAGGC TCTGGTGGGC CAAGCTGAGG ATTTCTCTGG TCGGGGAACA 
ATCGCTGTGA TTGAGCCAAT CTTCAAGGAA TATGGTGTGA TCTTTGCCAA TGGGGAACGC 
TGGAAGGCCC TTCGGCGATT CTCTCTGGCT ACCATGAGAG ACTTTGGGAT GGGAAAGAGG 
AGTGTGGAAG AACGGATTCA GGAGGAAGCC CAATGTTTGG TGGAGGAACT GCGGAAATCC 
CAGGGAGCCC CACTGGATCC CACCTTCCTC TTCCAGTGCA TCACAGCCAA CATCATCTGC 
TCCATTGTGT TTGGAGAGCG CTTTGACTAC ACAGACCGCC AGTTCCTGCG CCTGTTGGAG 
CTGTTCTACC GGACCTTTTC CCTCCTAAGT TCATTCTCCA GCCAGGTGTT TGAGTTCTTC 
TCTGGGTTCC TGAAATACTT TCCTGGTGCC CACAGACAAA TCTCCAAAAA CCTCCAGGAA 
ATCCTCGATT ACATTGGCCA TATTGTGGAG AAGCACAGGG CCACCTTAGA CCCAAGCGCT 
CCACGAGACT TCATCGACAC TTACCTTCTG CGCATGGAGA AGGTGAGTCC TGCATGGATG 
AGAGAGGAGA AGTCGAACCA CCACACAGTG TTCCATCATG AGAACCTCAT GATCTCCCTG 
CTCTCTCTCT TCTTTGCTGG CACTGAGACC AGCAGCACCA CACTCCGCTA TGGTTTCCTG 
CTGATGCTCA AGTACCCCCA TGTCGCAGAG AAAGTCCAAA AGGAGATTGA TCAGGTGATC 
GGCTCACACC GGCTACCAAC CCTTGATGAC CGCAGTAAAA TGCCATACAC TGATGCAGTT 
ATCCATGAGA TTCAGAGGTT TTCAGATCTT GTCCCTATTG GAGTACCACA CAGAGTCACC 
AAAGACACCA TGTTCCGAGG GTACCTGCTT CCCAAGAACA CTGAAGTGTA CCCCATCCTG 
AGTTCAGCTC TCCATGACCC ACAGTACTTT GACCACCCAG ACAGCTTCAA TCCTGAACAC 
TTCCTGGATG CCAATGGGGC ACTGAAAAAG AGTGAAGCTT TCATGCCCTT CTCCACAGGA 
AAGCGCATTT GTCTTGGCGA AGGCATTGCC CGAAATGAAT TGTTCCTCTT CTTCACCACC 
ATCCTCCAGA ACTTCTCTGT GTCAAGCCAT TTGGCTCCCA AGGACATTGA CCTCACGCCC 
AAGGAGAGTG GCATTGGAAA AATACCTCCA ACGTACCAGA TCTGCTTCTC AGCTCGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cyp2b1 ( XM_008765493.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008763715.1 Rattus norvegicus cytochrome P450, family 2, subfamily b, polypeptide 1 (Cyp2b1), transcript variant X4, mRNA.

Price & Availability↑

CloneID	ORa42885
Clone ID Related Accession (Same CDS sequence)	XM_008765493.1
Accession Version	XM_008765493.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1356bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	cytochrome P450 2B1 isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005106.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCAGCATC TTTCCCCTGC AGTGAAGCTT CGAGAAAAAT ATGGAGATGT GTTCACAGTA 
CACCTGGGAC CAAGGCCTGT GGTCATGCTA TGTGGGACAG ACACCATAAA GGAGGCTCTG 
GTGGGCCAAG CTGAGGATTT CTCTGGTCGG GGAACAATCG CTGTGATTGA GCCAATCTTC 
AAGGAATATG GTGTGATCTT TGCCAATGGG GAACGCTGGA AGGCCCTTCG GCGATTCTCT 
CTGGCTACCA TGAGAGACTT TGGGATGGGA AAGAGGAGTG TGGAAGAACG GATTCAGGAG 
GAAGCCCAAT GTTTGGTGGA GGAACTGCGG AAATCCCAGG GAGCCCCACT GGATCCCACC 
TTCCTCTTCC AGTGCATCAC AGCCAACATC ATCTGCTCCA TTGTGTTTGG AGAGCGCTTT 
GACTACACAG ACCGCCAGTT CCTGCGCCTG TTGGAGCTGT TCTACCGGAC CTTTTCCCTC 
CTAAGTTCAT TCTCCAGCCA GGTGTTTGAG TTCTTCTCTG GGTTCCTGAA ATACTTTCCT 
GGTGCCCACA GACAAATCTC CAAAAACCTC CAGGAAATCC TCGATTACAT TGGCCATATT 
GTGGAGAAGC ACAGGGCCAC CTTAGACCCA AGCGCTCCAC GAGACTTCAT CGACACTTAC 
CTTCTGCGCA TGGAGAAGGT GAGTCCTGCA TGGATGAGAG AGGAGAAGTC GAACCACCAC 
ACAGTGTTCC ATCATGAGAA CCTCATGATC TCCCTGCTCT CTCTCTTCTT TGCTGGCACT 
GAGACCAGCA GCACCACACT CCGCTATGGT TTCCTGCTGA TGCTCAAGTA CCCCCATGTC 
GCAGAGAAAG TCCAAAAGGA GATTGATCAG GTGATCGGCT CACACCGGCT ACCAACCCTT 
GATGACCGCA GTAAAATGCC ATACACTGAT GCAGTTATCC ATGAGATTCA GAGGTTTTCA 
GATCTTGTCC CTATTGGAGT ACCACACAGA GTCACCAAAG ACACCATGTT CCGAGGGTAC 
CTGCTTCCCA AGAACACTGA AGTGTACCCC ATCCTGAGTT CAGCTCTCCA TGACCCACAG 
TACTTTGACC ACCCAGACAG CTTCAATCCT GAACACTTCC TGGATGCCAA TGGGGCACTG 
AAAAAGAGTG AAGCTTTCAT GCCCTTCTCC ACAGGAAAGC GCATTTGTCT TGGCGAAGGC 
ATTGCCCGAA ATGAATTGTT CCTCTTCTTC ACCACCATCC TCCAGAACTT CTCTGTGTCA 
AGCCATTTGG CTCCCAAGGA CATTGACCTC ACGCCCAAGG AGAGTGGCAT TGGAAAAATA 
CCTCCAACGT ACCAGATCTG CTTCTCAGCT CGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008763715.1
CDS	543..1898
Translation	MQHLSPAVKLREKYGDVFTVHLGPRPVVMLCGTDTIKEALVGQAEDFSGRGTIAVIEPIFKEYGVIFANGERWKALRRFSLATMRDFGMGKRSVEERIQEEAQCLVEELRKSQGAPLDPTFLFQCITANIICSIVFGERFDYTDRQFLRLLELFYRTFSLLSSFSSQVFEFFSGFLKYFPGAHRQISKNLQEILDYIGHIVEKHRATLDPSAPRDFIDTYLLRMEKVSPAWMREEKSNHHTVFHHENLMISLLSLFFAGTETSSTTLRYGFLLMLKYPHVAEKVQKEIDQVIGSHRLPTLDDRSKMPYTDAVIHEIQRFSDLVPIGVPHRVTKDTMFRGYLLPKNTEVYPILSSALHDPQYFDHPDSFNPEHFLDANGALKKSEAFMPFSTGKRICLGEGIARNELFLFFTTILQNFSVSSHLAPKDIDLTPKESGIGKIPPTYQICFSAR

Target ORF information:

RefSeq Version	XM_008765493.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus cytochrome P450, family 2, subfamily b, polypeptide 1 (Cyp2b1), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008765493.1

ORF Insert Sequence:

ATGCAGCATC TTTCCCCTGC AGTGAAGCTT CGAGAAAAAT ATGGAGATGT GTTCACAGTA 
CACCTGGGAC CAAGGCCTGT GGTCATGCTA TGTGGGACAG ACACCATAAA GGAGGCTCTG 
GTGGGCCAAG CTGAGGATTT CTCTGGTCGG GGAACAATCG CTGTGATTGA GCCAATCTTC 
AAGGAATATG GTGTGATCTT TGCCAATGGG GAACGCTGGA AGGCCCTTCG GCGATTCTCT 
CTGGCTACCA TGAGAGACTT TGGGATGGGA AAGAGGAGTG TGGAAGAACG GATTCAGGAG 
GAAGCCCAAT GTTTGGTGGA GGAACTGCGG AAATCCCAGG GAGCCCCACT GGATCCCACC 
TTCCTCTTCC AGTGCATCAC AGCCAACATC ATCTGCTCCA TTGTGTTTGG AGAGCGCTTT 
GACTACACAG ACCGCCAGTT CCTGCGCCTG TTGGAGCTGT TCTACCGGAC CTTTTCCCTC 
CTAAGTTCAT TCTCCAGCCA GGTGTTTGAG TTCTTCTCTG GGTTCCTGAA ATACTTTCCT 
GGTGCCCACA GACAAATCTC CAAAAACCTC CAGGAAATCC TCGATTACAT TGGCCATATT 
GTGGAGAAGC ACAGGGCCAC CTTAGACCCA AGCGCTCCAC GAGACTTCAT CGACACTTAC 
CTTCTGCGCA TGGAGAAGGT GAGTCCTGCA TGGATGAGAG AGGAGAAGTC GAACCACCAC 
ACAGTGTTCC ATCATGAGAA CCTCATGATC TCCCTGCTCT CTCTCTTCTT TGCTGGCACT 
GAGACCAGCA GCACCACACT CCGCTATGGT TTCCTGCTGA TGCTCAAGTA CCCCCATGTC 
GCAGAGAAAG TCCAAAAGGA GATTGATCAG GTGATCGGCT CACACCGGCT ACCAACCCTT 
GATGACCGCA GTAAAATGCC ATACACTGAT GCAGTTATCC ATGAGATTCA GAGGTTTTCA 
GATCTTGTCC CTATTGGAGT ACCACACAGA GTCACCAAAG ACACCATGTT CCGAGGGTAC 
CTGCTTCCCA AGAACACTGA AGTGTACCCC ATCCTGAGTT CAGCTCTCCA TGACCCACAG 
TACTTTGACC ACCCAGACAG CTTCAATCCT GAACACTTCC TGGATGCCAA TGGGGCACTG 
AAAAAGAGTG AAGCTTTCAT GCCCTTCTCC ACAGGAAAGC GCATTTGTCT TGGCGAAGGC 
ATTGCCCGAA ATGAATTGTT CCTCTTCTTC ACCACCATCC TCCAGAACTT CTCTGTGTCA 
AGCCATTTGG CTCCCAAGGA CATTGACCTC ACGCCCAAGG AGAGTGGCAT TGGAAAAATA 
CCTCCAACGT ACCAGATCTG CTTCTCAGCT CGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Bromuconazole-induced hepatotoxicity is accompanied by upregulation of PXR/CYP3A1 and downregulation of CAR/CYP2B1 gene expression.
Toxicology mechanisms and methods27(7)544-550(2017 Sep)
Abdelhadya DH,El-Magd MA,Elbialy ZI,Saleh AA

Impacts of Blast-Induced Traumatic Brain Injury on Expressions of Hepatic Cytochrome P450 1A2, 2B1, 2D1, and 3A2 in Rats.
Cellular and molecular neurobiology37(1)111-120(2017 Jan)
Ma J,Wang J,Cheng J,Xiao W,Fan K,Gu J,Yu B,Yin G,Wu J,Ren J,Hou J,Jiang Y,Tan Y,Jin W

Expression of microRNAs, CYP1A1 and CYP2B1 in the livers and ovaries of female rats treated with DDT and PAHs.
Life sciences103(2)95-100(2014 May)
Chanyshev MD,Kosorotikov NI,Titov SE,Kolesnikov NN,Gulyaeva LF

Clofibric acid induces hepatic CYP 2B1/2 via constitutive androstane receptor not via peroxisome proliferator activated receptor alpha in rat.
Bioscience, biotechnology, and biochemistry78(9)1550-9(2014)
Ibrahim ZS,Ahmed MM,El-Shazly SA,Ishizuka M,Fujita S

Ascorbic acid deficiency decreases hepatic cytochrome P-450, especially CYP2B1/2B2, and simultaneously induces heme oxygenase-1 gene expression in scurvy-prone ODS rats.
Bioscience, biotechnology, and biochemistry78(6)1060-6(2014)
Kobayashi M,Hoshinaga Y,Miura N,Tokuda Y,Shigeoka S,Murai A,Horio F

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Cyp2b1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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